ライフサイエンスコーパス: stage

1 characteristics (i.e., histology, grade, and stage).

2 ygotic genome activation (ZGA) at the 2-cell stage.

3 tal processing on a single high-precision 3D stage.

4 hic lateral sclerosis from the early disease stage.

5 e diseases, with therapy adjusted to disease stage.

6 y develop into the metacyclic trypomastigote stage.

7 CT patients in the early, often asymptomatic stage.

8 eared to be independent of CD4+ count or WHO stage.

9 he nucleolus also appeared around the 8-cell stage.

10 encing or escalating treatment at an earlier stage.

11 ment, including the all-important infectious stage.

12 tonation at the lumirhodopsin I intermediate stage.

13 of an active pyruvate dehydrogenase in this stage.

14 to brain development at early developmental stages.

15 f potential roles during later developmental stages.

16 tissue microarrays across all developmental stages.

17 ival of mDANs during embryonic developmental stages.

18 cident patients with a diagnosis of melanoma stage 0 to III and with continuous insurance enrollment

19 e (American Joint Committee on Cancer [AJCC] stage 0, I, or II), and 48 (51.6%) were diagnosed with l

20 vember 25, 2013, 235 women undergoing PM for Stage 0-III breast cancer were randomized to undergo eit

21 he country by end of 2013; (2) proportion of stage 1 ever diagnosed; (3) proportion of stage 2 that e

22 while genes in Clade 3 are expressed later (stages 10-12).

23 was observed between the treatment groups in stage 2 of the trial.

24 of stage 1 ever diagnosed; (3) proportion of stage 2 that ever initiated ART; and (4) proportion of s

25 national scale connectivity assessments with stage 2 to evaluate possible spread of local outbreaks n

26 2 are expressed earlier than Clade 1 (anther stages 2-9), while genes in Clade 3 are expressed later

27 re infected by means of oral gavage with 200 stage 3 H polygyrus larvae.

28 (suPAR) levels strongly predict incident CKD stage 3 in adults.

29 lant recipients (6 trials), patients who had stage 3 to 5 CKD or were receiving dialysis (3 trials),

30 at ever initiated ART; and (4) proportion of stage 3 who became virally suppressed (</=200 copies/mL)

31 For stage 3, epidemic potential, we combined local and inter

32 The three stage 4 tumors contained mutations in genes encoding pro

33 tation occurred in all four tumors or in all stage 4 tumors.

34 e shafts, progressively increased from Binet stage A to Binet stage C, and was correlated with both l

35 a fission and show that it proceeds in three stages: a local constriction ("waist formation"), pulsat

36 ess vs more than three deliveries), prolapse stage (above the hymen vs at or beyond the hymen), and d

37 mpacts of cyclones on different life-history stages across the annual life cycle.

38 iduals at risk of developing AD and/or early stage AD for which current therapies may be more benefic

39 of Cardiology/American Heart Association HF stages among older individuals in the community.

40 In the acute stage, amusic patients exhibited decreased activation in

41 t parasites at the ring phase of the asexual stage and also gametocytogensis.

42 e host cell toxicity while maintaining blood-stage and gametocytocidal antimalarial activity and prot

43 PrepT-stage and prepN-stage can be estimated reproducibly.

44 c strength of prepN-stage was better than cN-stage and similar to ypN-stage (DeltaAIC 17.9 versus 6.2

45 Braak NFT stage and the presence of neuritic plaques were not sign

46 n of neural invasion in the cancer precursor stage and the resulting delay in the onset of PDAC-assoc

47 identified to be associated with a specific stage and/or type of cancer, which demonstrated the dyna

48 hromatin accessibility between developmental stages and could thereby represent putative enhancers.

49 levels, including at specific developmental stages and in specific tissues.

50 d deficit irrigation, cluster, developmental stages and two seasons (autumn 2015 and spring 2016) on

51 is critical for patient management for tumor staging and assessing treatment response.

52 f numerical metastatic LN burden may augment staging and better inform adjuvant treatment decisions.

53 surveillance, provide a framework for tumor staging and risk stratification, and select candidates f

54 ovements could lead to more accurate disease staging and robust measurements of changes in tau burden

55 edback drive (top-down context from the next stage), and prior drive (expectation).

56 . spinosum is highly depended on development stage, and harvest stage should be considered for altern

57 cantly correlated with T stage, N stage, TNM stage, and histological type of the disease.

58 A two-stage approach was used to estimate relative risks and 9

59 ecified outcome, IPD were analysed using a 1-stage approach.

60 find that beetle oocytes and embryos of all stages are abundant in heterogeneous 28-nucleotide RNA

61 ate (k=0.458) between MRI and histopathology staging assessments.

62 iated with shorter patient delay and earlier stage at breast cancer diagnosis.

63 In this study, we determine the precise stage at which SLs influence nodulation.

64 ations to explore the role of miRNA in early stage BC in young women, including ethnic specific diffe

65 stradiol vaginal ring in patients with early-stage BC receiving an AI; secondary objectives included

66 ns displayed the typical signature of a late stage biofilm, suggesting that biofilm formation is seve

67 20 to 44 years who were diagnosed with early-stage breast cancer and received a CPM increased in many

68 ALYs for all patients regardless of fibrosis stage, but was cost-effective only for patients with F3

69 inducing their proliferation and, at a late stage, by modulating OPC maturation.

70 sively increased from Binet stage A to Binet stage C, and was correlated with both local expansion of

71 f intermediary steps as well as direct, late stage C-7 hydroxylation provides both natural products i

72 PrepT-stage and prepN-stage can be estimated reproducibly.

73 ne expression in myocardial samples from end-stage CCC patients, compared to control samples from org

74 es, and also between cells of different cell stage, cell and tissue types, and organisms.

75 In end-stage chronic kidney disease, the option of organ transp

76 All elective resections for a T1-3N0-2M0 stage colorectal cancer were included between 2010 and 2

77 ed bacterial clearance during the bacteremic stage compared with controls.

78 Early floral stages constitutively accumulate greater amounts of two

79 luate biosynthetic absorbable mesh in single-staged contaminated (Centers for Disease Control class I

80 ytic-site maturation can be divided into two stages corresponding to the arrival of the early and lat

81 ients had more Barcelona Clinic Liver Cancer stage D ( P < .001), higher Model for End-Stage Liver Di

82 was better than cN-stage and similar to ypN-stage (DeltaAIC 17.9 versus 6.2 and 17.2, respectively).

83 Here, we determined disease stage-dependent changes in myocardial efficiency and eff

84 ovo in a rich extracellular environment in a stage-dependent manner producing complex microstructural

85 nase into genomic loci dispensable for blood stage development.

86 ne change in the percent uninsured and early-stage diagnosis among nonelderly patients with newly dia

87 Late-stage diagnosis of lung cancer occurs 95% of the time d

88 II), and 48 (51.6%) were diagnosed with late-stage disease (AJCC stage III or IV).

89 mented, 45 (48.4%) were diagnosed with early-stage disease (American Joint Committee on Cancer [AJCC]

90 odology was successfully applied to the late-stage diversification of natural products and a marketed

91 in classes of macrolide antibiotics via late-stage diversification.

92 where a temperature event during a sensitive stage drives a reduction in yield, or seasonal warming l

93 At later stages, during cancer growth and progression, additional

94 SR in NAFLD increased with advancing disease stage (e.g., higher in NASH than nonalcoholic fatty live

95 ll (iPSC) lines capturing a range of disease stages encompassing preleukemia, low-risk MDS, high-risk

96 CR has confirmed the differential life-cycle stage expression of a set of selected lincRNAs.

97 Our data show the staged expression of a variety of genes and identify mul

98 ent of the remaining patients until reaching stage F3.

99 rive (bottom-up from the previous processing stage), feedback drive (top-down context from the next s

100 onstrate that hepatic inflammation, fibrosis stage, fibrosis progression rate, hepatic infiltration o

101 favorable outcome of patients with advanced-stage FL treated with immunochemotherapy.

102 ene, NaJAZi, specifically expressed in early-stage floral tissues.

103 resent a new therapeutic option for advanced-stage follicular lymphoma.

104 uld be given high priority, and they set the stage for additional research moving forward.

105 a profound immune dysregulation, setting the stage for disease manifestations characteristic of M. ga

106 lding and experiment instructions to set the stage for dissemination and further development in educa

107 This platform provides a simple stage for systematic derivation of the entire range of e

108 lays in specialized metabolism, and sets the stage for understanding and controlling the central bran

109 ganese oxidizing complex, and describe early stage formation of its mineral products.

110 mammography and MR imaging for screening or staging from 2010 through 2014 were included.

111 nate immune response is regulated at various stages, from hematopoiesis to monocyte changes and macro

112 characteristics (i.e., age, gender, dementia stage, function, comorbidity, psychoactive medication us

113 motypes described for the first time as late-stage gametocyte-targeting molecules.

114 verlapping pre- from the post-Aire MHCII(lo) stage has been lacking.

115 ed myocardial samples from patients with end-stage heart failure at time of transplant, with or witho

116 d both imaging techniques to more accurately stage hepatic fibrosis in a rat model.

117 d number of leaves were higher at 4th growth stage; however, at this stage the end-use is not indicat

118 The t-system in end-stage human HF presents a characteristic novel phenotype

119 he majority of patients (80%) presented with stage I disease.

120 (+/- 6.2) kg/m(2), respectively, and 82% had stage I or II breast cancer.

121 e identified women diagnosed with unilateral stage I to III breast cancer between 1998 and 2012 withi

122 A total of 122 patients with stage I to III colon cancer were included.

123 0.878 for CCA versus control, 0.905 for CCA stage I-II versus control, 0.789 for PSC versus control,

124 rol, 0.796 for CCA versus PSC, 0.956 for CCA stage I-II versus PSC, 0.904 for HCC versus control, and

125 gram to identify veterans having surgery for stage I-III colorectal cancer from 1999 to 2010.

126 Complete resection (stages I and II) was achieved in 32 patients, and 28 pat

127 Women with stages I to III breast cancer who received all or part o

128 Patients and Methods Early-stage (I-III) AABCS were randomly assigned to a 6-month

129 For individuals with stage IB, adjuvant cisplatin-based chemotherapy is not r

130 Data on 17600 patients with stage II to III rectal adenocarcinoma from the 2006-2012

131 deep mutational analysis of 676 genes in 107 stages II to IV primary colorectal cancer, of which half

132 achieved in 32 patients, and 28 patients had stage III or IV disease.

133 were diagnosed with late-stage disease (AJCC stage III or IV).

134 ltivariable predictors of NAC treatment were stage (III), younger age (<40 yrs), Black or Hispanic ra

135 The patient's stage was T1bN2M0, stage IIIA.

136 potential therapy for MPS-I at a very early stage in life and represents a novel model to test UCB-b

137 5mg/g dry matter) in the later developmental stages in both forms, mainly ester-bound in the lignan m

138 ric oxide pathways are dysregulated at early stages in HD.

139 e patients with NASH, regardless of fibrosis stage; in overweight patients, surgery increased QALYs f

140 4 of 55; 62%), and were likely to experience stage IVE disease (n = 35 of 55; 64%), with bilateral in

141 eightened risk of developing chronic and end-stage kidney disease, an association that is largely att

142 ts of the major surface antigen of the blood stages known as Pf EMP1 encoded by up to 60 var genes pe

143 lt patients with cirrhosis and Model for End-Stage Liver Disease (MELD) score within 3 months of init

144 but the Lille (P < 0.0001) and Model for End-Stage Liver Disease (P < 0.0001) scores were independent

145 following recurrence included model for end-stage liver disease at LT >23, time to recurrence, >3 re

146 ed liver fibrosis is a critical step for end-stage liver disease progression.

147 er stage D ( P < .001), higher Model for End-Stage Liver Disease Sodium scores ( P < .001), higher Ch

148 nostic accuracy of the imaging parameters in staging liver fibrosis.

149 Exposure to blood-stage malaria infection is often persistent, leading to

150 In end-stage mesothelioma, silencing of p16/Ink4a is sustained

151 /C receptors and abolished spasticity in end-stage mice.

152 a and North Carolina dated to Marine Isotope Stage (MIS) 3, from 50 to 35 ka, are surprisingly high f

153 was estimated at each current age using a 2-stage modelling approach that accounted for both age at

154 ate that, in the case of the three- and four-stage models, several parameters that are theoretically

155 re may be no significant benefit with single-stage MV-PCI compared with CO-PCI.

156 uced PDW was significantly correlated with T stage, N stage, TNM stage, and histological type of the

157 s tumor heterogeneity and evolution in early-stage non-small cell lung cancer.

158 d to platinum-based chemotherapy in advanced-stage non-squamous NSCLC.

159 tiregion whole-exome sequencing on 100 early-stage NSCLC tumors that had been resected before systemi

160 During the liver stage of a malaria infection, Plasmodium parasites are t

161 short course of IVIG administered in the MCI stage of AD reduces brain atrophy, prevents cognitive de

162 iple vaccine strategies have advanced to the stage of clinical evaluation with unprecedented speed.

163 ndependent brain atrophy during the earliest stage of disease.

164 hs were measured repeatedly during the early stage of growth.

165 cle in the clinically relevant asexual blood stage of infection(1).

166 understanding of science, the main goal, the stage of involvement in the research process, and the sc

167 ntal cortex, becomes active during the early stage of learning a novel vocabulary.

168 do PGCCs acquire such stemness, and to which stage of normal development do PGCCs correspond.

169 lucidate the general picture of the advanced stage of plant cell specialization and to reveal novel p

170 ree tool to detect abnormalities at an early stage of pregnancy, a GO-peptide-based surface plasmon r

171 x, birth weight, height, body weight, Tanner stage of pubertal development, axial length, and spheric

172 t on the specific therapeutic target and the stage of PVR.

173 curring during the initiation and maturation stage of reprogramming in partially and fully reprogramm

174 tion can facilitate passage to the succeding stage of the cell cycle.

175 ng movement is widely available at the input stage of the cerebellar cortex, as required by forward m

176 he only DEGs to be expressed during only one stage of the estrous cycle (metestrus).

177 tion of eligible patients who completed each stage of the HCV Continuum of Care.

178 osis/cytokinesis is common in the blastomere stage of the preimplantation embryo.

179 The primary outcome for the phase 3 stage of the trial was overall survival (defined as the

180 ms after stimulus onset at a post-perceptual stage of visual processing.

181 t reliable genes among different tissues and stages of ALB.

182 tify NPC subtypes and critical developmental stages of alternative lineage specifications.

183 ed miRNAs at the intermediate and late Braak stages of Alzheimer's disease (AD), as well as in other

184 motif, play a critical role in the earliest stages of AP2 activation and CCP nucleation.

185 At early stages of Arabidopsis (Arabidopsis thaliana) flowering,

186 aimed to profile the microbiota at different stages of Barrett's carcinogenesis and investigate the C

187 ssociated protein on the motile and invasive stages of both human and rodent parasites.

188 and may target different cells at different stages of brain development.SIGNIFICANCE STATEMENT Zika

189 This isoform is highly expressed in advanced stages of breast and cervical tumors.

190 embrane removal predominates during the late stages of cytokinesis, mediated by both dynamin and the

191 EGFP expression in lymphatic vessels at all stages of development and in adult zebrafish.

192 nts differential effects among four critical stages of development and provides insight into factors

193 ine and NF54 wild-type parasites at multiple stages of development, we show that sexually committed,

194 eneous range of migratory behaviors at later stages of development, with the acquisition of complex m

195 potential of a protein to be toxic at early stages of development.

196 ies, allowing function analyses at different stages of development.

197 oderm with complete epithelial loss at later stages of development.

198 ta; 2 ng/L and 50 ng/L) during four distinct stages of development: gonad development, gonad differen

199 in mammalian stem cells and cells at various stages of differentiation.

200 n vivo, we depleted neutrophils at different stages of disease.

201 opulations of patients with IBD at different stages of disease.

202 criterion for establishing prognosis in all stages of disease.

203 In the early stages of endocytosis, fPlas-gold nanoparticles appear m

204 ith sham control (P=0.028 accounting for all stages of exercise).

205 At advanced stages of FSGS, fawn-hooded hypertensive rat kidneys exh

206 r variable among female mussels at different stages of gonad development.

207 ct observation of nanoparticles in the early stages of growth with unobtrusive laser probes should gi

208 odic memory and motor function with advanced stages of HIV infection suggests that these two domains

209 es across substrates representing maturation stages of human VRC-PG04.

210 isolating certain types of cells at defined stages of in planta development for in-depth analysis.

211 arkers of infection present during different stages of infection (viral nonstructural protein 1 and i

212 s in the cytoskeleton at both early and late stages of infection.

213 te residues, which was installed in the late stages of laboratory evolution, apparently enhances lysi

214 Advanced stages of liver cirrhosis lead to a dramatically increas

215 44 RNA sequencing data sets covering various stages of macronutrient deficiencies and symbiotic inter

216 s a new system with potential to study early stages of NBL oncogenesis, to functionally assess NBL on

217 ochastic models that can both deconvolve the stages of polymerase activity and identify significant c

218 r plant and play a central role in the early stages of programmed cell death (apoptosis).

219 ecially poorly understood are the very early stages of protein folding, which are likely defined by i

220 otamine sulfur-sulfur bonds during the final stages of sperm maturation.

221 DTA had some inhibitory effects in the early stages of storage.

222 tions in transcription rate during the early stages of stress response, indicating orthogonal transcr

223 resource specialization during the incipient stages of sympatric divergence.

224 cillary proteins that intercede at different stages of the assembly pathway.

225 acture risk among T2DM patients in the early stages of the disease.

226 in South Africa, deposited during the early stages of the first rise in atmospheric oxygen on the Ea

227 ebrile to the defervescence and convalescent stages of the infection.

228 okine receptors and ligands control multiple stages of this process, their involvement during early t

229 and invasive cancers and may influence early stages of tumorigenesis.

230 D subtype in linear regression analysis, but staging of alpha-synuclein pathologic changes was unrela

231 Scans were obtained for primary staging of intermediate- and high-risk disease in 25% of

232 ing multiple primaries, allowing appropriate staging of the patient.

233 hip between volume percent of primary growth stage oocytes or gonadosomatic index and rRNA content, d

234 ions between mutated genes and pathways, and stage or subtype of T-ALL.

235 irectly by finding breast cancers at earlier stages or indirectly by heightening women's awareness of

236 2.01 to 75.94; P = .007), and higher Tanner stage (OR, 5.42; 95% CI, 1.75 to 16.78; P = .003) were a

237 ren who were parasite free, harbored asexual stages, or had gametocytes at submicroscopic densities.

238 rough a Friedel-Crafts triflation and a late-stage oxidation of a furan ring.

239 t of age (P < 0.001), T stage (P < 0.001), N stage (P < 0.001), and grade (P = 0.049).

240 P < 0.001) independent of age (P < 0.001), T stage (P < 0.001), N stage (P < 0.001), and grade (P = 0

241 ts Plasmodium falciparum PKG, inhibits blood stage parasite growth in vitro and in mice and blocks tr

242 The paper presents a novel two-stage particle swarm optimization (PSO) for the maximum

243 ic candidates could be developed through a 2-stage path.

244 opportunity for controlled release in higher-stage patients.

245 In this ongoing single-centre, two-stage, phase 2, single-arm trial, patients (aged >/=16 y

246 " treat all patients, regardless of fibrosis stage; policy 2, treat only "prioritized" patients, dela

247 n significantly increases at advanced cancer stages, providing an improved opportunity for controlled

248 on brain function and/or treatment in early-stage psychosis populations are needed.

249 uris longus muscle from male and female late-stage R6/2 mice and age-matched wild-type controls.

250 SABRINA is a two-stage, randomised, open-label phase 3 study at 113 centr

251 ting cells (TIC) is vital to combat advanced-stage recurrent cancers.

252 ECR was associated with development of end-stage renal disease (ESRD).

253 lt of longer survival, the prevalence of end-stage renal disease in HIV is increasing.

254 a reduced risk of future progression to end-stage renal disease.

255 iew, we describe speculative ideas and early stage research concerning the flow of genetic informatio

256 c mechanisms, can substantially affect early-stage sensory signal processing and subsequent behaviora

257 y depended on development stage, and harvest stage should be considered for alternative uses of end-p

258 ogically or histologically confirmed limited-stage small-cell lung cancer, Eastern Cooperative Oncolo

259 Imbalanced early-stage sound level processing could partially explain the

260 urther upregulated in pDCs, correlating with stage-specific activity of multiple enhancer elements.

261 Our data reveal that tissue and stage-specific expression of ankyrin isoforms relies on

262 Stage-specific gene deletion in trophoblasts reveals tha

263 The LTRs function in a stage-specific manner during the oocyte-to-embryo transi

264 The identity of stage-specific metabolic programs and their impact on ad

265 poietic phenotypes of graded severity and/or stage specificity that together delineate a phenotypic r

266 patients with 23 LM or LMM lesions underwent staged surgery and contributed to the analysis.

267 es of advanced disease, higher international staging system score, increased incidence of high-risk c

268 togenetics, and higher revised international staging system score.

269 Only the Nakanuma staging system was independently associated with endpoin

270 r Italian Program, and tumor-node-metastasis staging systems; had no macrovascular invasion; and show

271 efined two major genomic subtypes of primary stage Ta tumors.

272 influence on the time to development of end-stage TB.

273 tudy neonatal hematopoiesis, a developmental stage that has been difficult to analyze to date.

274 higher at 4th growth stage; however, at this stage the end-use is not indicated for raw consumption b

275 waiting LT and treated with bridging or down-staging therapies before LT.

276 was significantly correlated with T stage, N stage, TNM stage, and histological type of the disease.

277 allows disease to progress from a very early stage to a lethal state.

278 it will be done." Moving from a theoretical stage to this hopeful era of possibilities, new challeng

279 potential dispersal and delayed development stages to infer the major forces shaping range edges and

280 lly methylated gene regions (DMGRs) in early stage tumors across eleven genes (AGRN, C1orf170, FAM41C

281 nuclear factor 4A knockout mice; were early-stage tumors by Barcelona Clinic Liver Cancer, Cancer of

282 an invasion ligand that is a potential blood-stage vaccine candidate antigen; however, a naturally oc

283 molgi as a model in the development of blood stage vaccines against vivax malaria.

284 to erosion such that in the early evolution stages, vegetation removal results in gullying, but that

285 rural areas during the complementary feeding stage was associated with a 0.002-SD decrease in HAZ (P

286 In contrast, prognostic strength of prepN-stage was better than cN-stage and similar to ypN-stage

287 Of the 93 women for whom stage was documented, 45 (48.4%) were diagnosed with ear

288 The agreement for T stage was good/substantial (k=0.790) and for N stage was

289 Cytotoxicity at the early stage was investigated on twenty types of polymers (posi

290 age was good/substantial (k=0.790) and for N stage was moderate (k=0.458) between MRI and histopathol

291 The patient's stage was T1bN2M0, stage IIIA.

292 In most tissues and developmental stages we observe a relative contribution of KRas4B > >

293 with beta2m amyloid formation at the monomer stage, we found that doxycycline and rifamycin SV exert

294 ar involvement at presentation, and advanced stage were significantly correlated with shorter PFS (P

295 Stages were defined as (1) number of people living with

296 -stress impacts, both pre- and postflowering stages were identified to be equally important for overa

297 he commercial harvest (CH) or tree-ripe (TR) stages were immediately exposed to cold treatment (40 d,

298 Embryos (1-4 cell stage) were microinjected with either 1 or 10 ng venlafa

299 different genes are reactivated at different stages, with more slowly reactivated genes tending to be

300 At later stages, younger beta-cells join the islet following diff