ライフサイエンスコーパス: staphylococcal enterotoxin B

1 n of peripheral blood mononuclear cells with staphylococcal enterotoxin B.

2 nonimmune rabbits or rabbits immunized with staphylococcal enterotoxin B.

3 induced by the atopic dermatitis-associated staphylococcal enterotoxin B.

4 was reduced by anti-class II MHC Abs and by staphylococcal enterotoxin B.

5 syngeneic T cell-proliferative responses to staphylococcal enterotoxin B.

6 mphocytes in IFN-gamma-/- mice injected with staphylococcal enterotoxin B.

7 cells of mice immunized with a superantigen, staphylococcal enterotoxin B.

8 lood mononuclear cells (PBMCs) stimulated by staphylococcal enterotoxin B.

9 ules (MTs) is described for the detection of staphylococcal enterotoxin B.

10 positive blastospores or Pep(263) but not by staphylococcal enterotoxin B.

11 hen egg lysozyme, cholera toxin, ricin, and staphylococcal enterotoxin B.

12 vivo and in vitro following stimulation with staphylococcal enterotoxin B.

13 s, the loading of an I-A(b)-binding peptide, staphylococcal enterotoxin B 121-136, onto T2-I-A(b) cel

14 In this report, we show that exposure to staphylococcal enterotoxin B, a bacterial superantigen,

15 iber-optic biosensor has been used to detect staphylococcal enterotoxin B, a causative agent of food

16 This phenotype was reproduced with staphylococcal enterotoxin B, a heterologous SAg that al

17 pe mice were injected intraperitoneally with staphylococcal enterotoxin B, a pyrogenic superantigen,

18 ein and the T-cell receptor and can redirect staphylococcal enterotoxin B-activated T cells to kill i

19 In this study, we show that staphylococcal enterotoxin B activates a Galphaq and PLC

20 Animals treated with lipopolysaccharide or Staphylococcal enterotoxin B alone became tolerant and d

21 were treated daily with saline, 50 microg/kg Staphylococcal enterotoxin B alone, 1000 microg/kg lipop

22 n of naive CD4(+) T lymphocytes with soluble staphylococcal enterotoxin B and anti-CD28.

23 ive response of CD3epsilon.PRS(M) T cells to staphylococcal enterotoxin B and anti-CD3 Ab was normal.

24 e was mecA, Panton-Valentine leukocidin, and staphylococcal enterotoxin B and C negative, toxic shock

25 alysis (BIAcore) revealed that scFvs against staphylococcal enterotoxin B and cholera toxin B subunit

26 c-field-driven assay for fluorescein-labeled staphylococcal enterotoxin B and cholera toxin B was dev

27 in the vaccine, as assessed by responses to staphylococcal enterotoxin B and cytomegalovirus antigen

28 respond poorly to the bacterial superantigen staphylococcal enterotoxin B and do not respond to pepti

29 ed with lipid-complexed plasmid DNA encoding staphylococcal enterotoxin B and either GM-CSF or IL-2.

30 bsequently, solutions of fluorescein-labeled staphylococcal enterotoxin B and fluorescein-labeled cho

31 It was determined that neither staphylococcal enterotoxin B and interleukin-2 activatio

32 logous lymphocytes, activated in vitro using staphylococcal enterotoxin B and interleukin-2 and then

33 in model buffer (PBS-BSA) and 0.1 ng/mL for staphylococcal enterotoxin B and LT.

34 lized the clinically important superantigens staphylococcal enterotoxin B and TSS toxin-1 with a sing

35 ssays for detection of both a protein toxin (staphylococcal enterotoxin B) and a small molecule (2,4,

36 potential biological warfare agents, ricin, staphylococcal enterotoxin B, and epsilon toxin, in comp

37 of detection for the toxins (cholera toxin, staphylococcal enterotoxin B, and ricin) were 1.6, 0.064

38 was induced in wild-type mice injected with staphylococcal enterotoxin B, and the administration of

39 iomeningitis virus) infection and bacterial (staphylococcal enterotoxin B) antigen immunization.

40 nd TNF-alpha in CD8(+) T cells responding to staphylococcal enterotoxin B appeared to be largely segr

41 hal doses of staphylococcal enterotoxin A or staphylococcal enterotoxin B at 1 day after burn injury

42 de including the organic photodiode detected Staphylococcal enterotoxin B at concentrations as low as

43 Exposure to the superantigen staphylococcal enterotoxin B augments SLP-76 expression

44 s, including the two MRSA isolates, produced staphylococcal enterotoxins B, C, D, and E on overnight

45 cular permeability, and death in response to staphylococcal enterotoxin B challenge compared with wil

46 In response to staphylococcal enterotoxin B challenge, up-regulation of

47 ccessful in the detection of protein toxins (staphylococcal enterotoxin B, cholera toxin).

48 g viral infection primes mice for subsequent staphylococcal enterotoxin B exposure, possibly via a ga

49 -10 (Fo = 0.16% versus 0.007%; p = 0.04) and staphylococcal enterotoxin B (Fo = 0.49% versus 0.26%; p

50 t mice did not show increased sensitivity to staphylococcal enterotoxin B following adenoviral infect

51 crog/kg lipopolysaccharide with 50 microg/kg Staphylococcal enterotoxin B for 10 days.

52 ecific for CMV pp65(495-503) epitope, or for staphylococcal enterotoxin B, for the expression pattern

53 ystemic adenoviral infection on responses to staphylococcal enterotoxin B in a murine model.

54 epatitis induced by administration of LPS or staphylococcal enterotoxin B in the presence of D-galact

55 n this report show that 1) responsiveness to staphylococcal enterotoxin B in V beta6 T cells was tran

56 re gene expression in T cells activated with staphylococcal enterotoxin B in vivo then cultured with

57 Coinjection of D-galactosamine and LPS or staphylococcal enterotoxin B induced a rapid-onset, low-

58 pplications of a house dust mite extract and Staphylococcal enterotoxin B induced eczematous skin les

59 ich is clearly demonstrated by superantigen (staphylococcal enterotoxin B)-induced deletion of Vbeta8

60 in kinase C-theta (PKC-theta), superantigen (staphylococcal enterotoxin B)-induced deletion of Vbeta8

61 etion of thymocytes, bacterial superantigen (staphylococcal enterotoxin B)-induced elimination of per

62 y similar between human AD skin and allergen/staphylococcal enterotoxin B-induced mouse skin lesions,

63 nditions mimicking a robust immune response (staphylococcal enterotoxin B-induced T cell activation).

64 Staphylococcal enterotoxin B induces toxic shock and is

65 gly, anergic Vbeta8(+) T cells isolated from staphylococcal enterotoxin B-injected mice did not exhib

66 alone, coadministration of LPS plus IL-12 or staphylococcal enterotoxin B into scid/scid mice 1 day a

67 tive laser-induced fluorescence detection of staphylococcal enterotoxin B is presented.

68 The combination of lipopolysaccharide and Staphylococcal enterotoxin B leads to late liver injury,

69 gnificant cell adhesion or later response to staphylococcal enterotoxin B-MHC complexes only when Ag

70 -2 in CD4(+) cells that were stimulated with staphylococcal enterotoxin B or cytomegalovirus antigen.

71 PBMC were cultured for 7 d with staphylococcal enterotoxin B or IL-7 in the absence or p

72 erferon-gamma, on mitogenic stimulation with staphylococcal enterotoxin B or on antigenic stimulation

73 Naive T cells primed by (staphylococcal enterotoxin B or tumor-associated protein

74 T, mmCT, or dmLT plus a polyclonal stimulus (staphylococcal enterotoxin B) or specific bacterial Ags,

75 mitogen (phytohemagglutinin), superantigen (staphylococcal enterotoxin B), or anti-CD3 antibody were

76 crog/kg lipopolysaccharide with 50 microg/kg Staphylococcal enterotoxin B, or 100 microg/kg lipopolys

77 Choric exposure to staphylococcal enterotoxin B precipitated a lupus-like i

78 , like TSST-1, is peptide dependent, whereas staphylococcal enterotoxin B presentation is peptide ind

79 strated decreased pulmonary HIV-specific and staphylococcal enterotoxin B-reactive CD4(+) memory resp

80 howed significant variability over time, but staphylococcal enterotoxin B responses remained relative

81 beta-chain junctional regions of a panel of staphylococcal enterotoxin B-responsive V beta6 T hybrid

82 Chronic exposure to staphylococcal enterotoxin B resulted in a multisystem a

83 on-Tg and Fas-Tg mice, challenging mice with staphylococcal enterotoxin B resulted in significantly h

84 ng in vivo stimulation with the superantigen staphylococcal enterotoxin B resulting in increased T ce

85 d in 15 min, and detection of cholera toxin, staphylococcal enterotoxin B, ricin, and Bacillus globig

86 s could be detected in a single 3 x 3 array: Staphylococcal enterotoxin B, ricin, cholera toxin, Baci

87 perantigens staphylococcal enterotoxin A and staphylococcal enterotoxin B (SEB) 7 days later enhanced

88 ta-chain-SEC3 complex, (2) a complex between staphylococcal enterotoxin B (SEB) and an MHC molecule,

89 after exposure to pathogen-derived inducers staphylococcal enterotoxin B (SEB) and lipopolysaccharid

90 Murine lymphocytes responded less well to staphylococcal enterotoxin B (SEB) and SEA, but mouse ce

91 evaluated the local and systemic effects of staphylococcal enterotoxin B (SEB) and streptococcal pyr

92 TCR beta chain (mouse V beta8.2) and the SAG staphylococcal enterotoxin B (SEB) at 2.4 A resolution r

93 phytohemagglutinin (PHA) or the superantigen staphylococcal enterotoxin B (SEB) caused a 3- to 6-fold

94 Staphylococcal enterotoxin B (SEB) causes food poisoning

95 BALB/c mice were exposed to staphylococcal enterotoxin B (SEB) either systemically o

96 We observed that staphylococcal enterotoxin B (SEB) enhanced the IL-4 Der

97 assay (RPLA), were selected for detection of staphylococcal enterotoxin B (SEB) from 77 clinical Stap

98 id substitutions at specific residues of the staphylococcal enterotoxin B (SEB) gene cloned from Stap

99 Using anti-staphylococcal enterotoxin B (SEB) IgG as a "gate" and S

100 e method for the detection of a model toxin, staphylococcal enterotoxin B (SEB) in buffer, apple juic

101 Intranasal exposure to staphylococcal enterotoxin B (SEB) in C57BL/6 wild-type

102 s article, we present the x-ray structure of staphylococcal enterotoxin B (SEB) in complex with its r

103 nologies is used to improve the detection of Staphylococcal enterotoxin B (SEB) in food.

104 production as well as toxic shock induced by staphylococcal enterotoxin B (SEB) in HLA class II trans

105 ed the effects of the bacterial superantigen staphylococcal enterotoxin B (SEB) in mice.

106 T cells from wild-type mice were primed with staphylococcal enterotoxin B (SEB) in vitro, which induc

107 We activated Vbeta8(+) T cells with staphylococcal enterotoxin B (SEB) in vivo and monitored

108 In normal mice, injection of 1-100 microg of staphylococcal enterotoxin B (SEB) induced clonal elimin

109 consequences of Mycobacterium bovis BCG and staphylococcal enterotoxin B (SEB) inoculation in vivo i

110 The bacterial superantigen staphylococcal enterotoxin B (SEB) interacts with T cell

111 Staphylococcal enterotoxin B (SEB) is a bacterial supera

112 Staphylococcal enterotoxin B (SEB) is a bacterial supera

113 Staphylococcal enterotoxin B (SEB) is a potent superanti

114 Staphylococcal enterotoxin B (SEB) is a potent toxin tha

115 Staphylococcal enterotoxin B (SEB) is a superantigen kno

116 Staphylococcal enterotoxin B (SEB) is a superantigen tha

117 Staphylococcal enterotoxin B (SEB) is a superantigen tha

118 T-cell stimulating activity of Staphylococcal enterotoxin B (SEB) is an important facto

119 re to the Staphylococcus aureus superantigen staphylococcal enterotoxin B (SEB) may occur accidentall

120 we measured the binding of a set of SEC3 and staphylococcal enterotoxin B (SEB) mutants to soluble re

121 d the utility of two recombinantly expressed Staphylococcal Enterotoxin B (SEB) mutants, a single poi

122 Various in vitro effects of staphylococcal enterotoxin B (SEB) on human peripheral b

123 with purified T cells and the superantigens staphylococcal enterotoxin B (SEB) or toxic shock syndro

124 lpha), while stimulation of these cells with staphylococcal enterotoxin B (SEB) or toxic shock syndro

125 l clone HA-1.70 with either the superantigen staphylococcal enterotoxin B (SEB) or with a specific an

126 Systemic exposure to staphylococcal enterotoxin B (SEB) rapidly and selective

127 Stimulation of T-cells with staphylococcal enterotoxin B (SEB) significantly elevate

128 The superantigen staphylococcal enterotoxin B (SEB) simultaneously binds

129 oduced interferon (IFN) gamma in response to staphylococcal enterotoxin B (SEB) stimulation in 382 he

130 When mice were injected with staphylococcal enterotoxin B (SEB) superantigen and H57-

131 A macaque model was employed to explore staphylococcal enterotoxin B (SEB) superantigen-driven T

132 fall into two groups: superantigens such as staphylococcal enterotoxin B (SEB) that contain a single

133 de inhibits the binding of the super-antigen staphylococcal enterotoxin B (SEB) to IAk.

134 m. immunization of rabbits with formalinized staphylococcal enterotoxin B (SEB) toxoid in saline elic

135 esent a new homogeneous detection method for staphylococcal enterotoxin B (SEB) utilizing core-shell-

136 ection system for immunological detection of staphylococcal enterotoxin B (SEB) was designed, fabrica

137 A candidate vaccine against staphylococcal enterotoxin B (SEB) was developed using a

138 A rapid and sensitive detection of staphylococcal enterotoxin B (SEB) was developed using a

139 ine production to an exogenous superantigen, staphylococcal enterotoxin B (SEB) was diminished in HLA

140 lasmon resonance (SPR) detection signal from staphylococcal enterotoxin B (SEB) was dramatically incr

141 or Bacillus globigii, MS2 bacteriophage, and staphylococcal enterotoxin B (SEB) were 10(5) cfu/mL, 10

142 Staphylococcal enterotoxin B (SEB), a potential biologic

143 Staphylococcal enterotoxin B (SEB), a primary cause of f

144 Staphylococcal enterotoxin B (SEB), a shock-inducing exo

145 Bacterial superantigens, such as staphylococcal enterotoxin B (SEB), can trigger acute pa

146 Superantigens, such as staphylococcal enterotoxin B (SEB), elicit a strong prol

147 t physiologically relevant concentrations of staphylococcal enterotoxin B (SEB), F1 antigen from Yers

148 ss spectrometry to identify a protein toxin, staphylococcal enterotoxin B (SEB), in a model food matr

149 Staphylococcal superantigens, including staphylococcal enterotoxin B (SEB), promote vigorous T c

150 e TCR Vbeta domain fail to respond the bSAGs staphylococcal enterotoxin B (SEB), SEC1, SEC2, and SEC3

151 Clostridium perfringens epsilon toxin (ETX), staphylococcal enterotoxin B (SEB), shiga toxin (STX), a

152 the potential role played by superantigens, staphylococcal enterotoxin B (SEB), staphylococcal enter

153 rvival after challenge with the superantigen staphylococcal enterotoxin B (SEB), using lipopolysaccha

154 the ability of two overlapping fragments of staphylococcal enterotoxin B (SEB), which encompass the

155 esicular stomatitis virus (VSV) can redirect staphylococcal enterotoxin B (SEB)-activated T cells to

156 5) and Fas ligand (FasL) play major roles in staphylococcal enterotoxin B (SEB)-induced peripheral de

157 cycle upon stimulation with the superantigen staphylococcal enterotoxin B (SEB).

158 ntiation of T cells following treatment with staphylococcal enterotoxin B (SEB).

159 ultures were stimulated with graded doses of staphylococcal enterotoxin B (SEB).

160 intracutaneous injection of small amounts of staphylococcal enterotoxin B (SEB).

161 d immunoassays of a common food-borne toxin, Staphylococcal enterotoxin B (SEB).

162 ufficient counterparts for responsiveness to staphylococcal enterotoxin B (SEB).

163 xemplified by ricin, cholera toxin (CT), and staphylococcal enterotoxin B (SEB).

164 finity agents to neutralize the potent toxin staphylococcal enterotoxin B (SEB).

165 lls are hyperresponsive to SAgs, typified by staphylococcal enterotoxin B (SEB); ii) the human MAIT c

166 or saline control (n = 30) for 60 hrs after staphylococcal enterotoxin B (SEB; 10 microg iv) and a s

167 administration by a single i.p. injection of staphylococcal enterotoxin B (SEB; 10 micrograms/mouse)

168 ts in the activation of human T cells by the staphylococcal enterotoxins B (SEB), C1 (SEC1), and D (S

169 ermore, syndecan-1-null mice challenged with staphylococcal enterotoxin B showed enhanced T cell accu

170 e with TCR transgenic mice or treatment with staphylococcal enterotoxin B showed that the defect was

171 Prior host exposure to staphylococcal enterotoxin B significantly enhanced fibr

172 Two days after exposure to the superantigen staphylococcal enterotoxin B, splenocytes cultured with

173 Staphylococcal enterotoxin B stimulated similar cytokine

174 ent of loss of memory CD4+ T lymphocytes and staphylococcal enterotoxin B-stimulated cytokine product

175 Staphylococcal enterotoxin B-stimulated IL-2-producing c

176 gp modulation, P-gp activity was measured in staphylococcal enterotoxin B-stimulated peripheral blood

177 uantified in either anti-CD3/28 antibody- or staphylococcal enterotoxin B-stimulated single-positive

178 hanced activation-induced proliferation (via staphylococcal enterotoxin B stimulation) but inhibited

179 In response to staphylococcal enterotoxin B stimulation, beta-cat(Tg) m

180 n of T cells in responses to anti-CD3 mAb or staphylococcal enterotoxin B stimulation.

181 cytokine production by cells in response to staphylococcal enterotoxin B stimulation.

182 vide or divided only once in the presence of staphylococcal enterotoxin B, suggesting that virus prod

183 deletion of CD4+/CD8+ thymocytes induced by staphylococcal enterotoxin B superantigen and specific p

184 Finally, the inoculation of staphylococcal enterotoxin B superantigen into SIV-infec

185 vels of this cytokine after stimulation with staphylococcal enterotoxin B superantigen.

186 with CpG and stimulation of the TCR with the staphylococcal enterotoxin B superantigen.

187 n the in vitro response to the superantigen, staphylococcal enterotoxin B, the usually observed parti

188 to TSS induced by an unrelated superantigen (staphylococcal enterotoxin B), they were completely resi

189 capable of continuously delivering the SAg, staphylococcal enterotoxin B (total of 10 mug/mouse), or

190 hat the PLCbeta inhibitor U-73122 sensitizes staphylococcal enterotoxin B-treated mice to dexamethaso

191 ty and percentage of IL-15-positive cells in Staphylococcal enterotoxin B-treated monocytes of AD pat

192 IL-15 secretion by Staphylococcal enterotoxin B-treated PBMC of AD patients

193 In adenovirus-infected mice, staphylococcal enterotoxin B triggered a more profound h

194 ative response of Vbeta8(+)CD4(+) T cells to staphylococcal enterotoxin B was comparable in LIGHT(-/-

195 +)CD8(+) T cell proliferation in response to staphylococcal enterotoxin B was significantly lower in

196 T cells stimulated with anti-CD3 antibody or staphylococcal enterotoxin B, we found that chlorampheni

197 holera toxin, ricin, shiga-like toxin 1, and staphylococcal enterotoxin B were performed simultaneous

198 ytes, and leukocytes stimulated ex vivo with Staphylococcal enterotoxin B, which mimics some of the c

199 verity of liver injury following exposure to staphylococcal enterotoxin B without d-galactosamine sen