ライフサイエンスコーパス: start

1 - weeks or months before the rains typically start.

2 injection were not sufficient to generate S-starts.

3 rug discovery is fraught with many stops and starts.

4 An oral corticosteroid treatment was started.

5 evels of IL-17 and IL-36 family of cytokines starting 1 week after DLX3 deletion.

6 Women were enrolled in Right from the Start (2004-2010) prospective cohort.

7 Follow-up started 3 months after either the latest of the beginnin

8 Births among HIV-infected women who started 3-drug ART regimens before their last menstrual

9 mediated CD4(+) T-cell depletion in HF mice (starting 4 weeks after ligation) reduced cardiac infiltr

10 erform a second type of startle called the S-start [5-7].

11 merular filtration rate decline was observed starting a decade later in life in the 30- to 39-year ag

12 ng placebo treatment and two occurred before starting active treatment.

13 than 4.0 ng/mL between 6 and 12 months after starting ADT.

14 The mean starting ages for IBI were 5.24 years for CWT, 3.89 year

15 spital of Eastern Ontario IBI center for the starting ages.

16 patients was 27.8 (10.1) years at the study start and 41.0 (10.0) years at the time of surgery.

17 gest different roles for each subtype at the start and end of tethered-walking turns.

18 s in the change in IBDQ-B scores between the start and nadir was not significant (P = 0.093).

19 identified a set of reads with well-defined start and stop positions, in a length range of 16 to 22

20 sideration of when pharmacotherapy should be started and choice of medication and duration of treatme

21 rtant for understanding when plate tectonics started and how the supply of nutrients to the oceans ch

22 studies with immune checkpoint blockade have started and the results are awaited with great interest.

23 nces in organ doses were not related to tube start angles (P = .17).

24 Sixteen of 64 (25%) had a stroke soon after starting antiretroviral therapy (ART), suggesting an imm

25 Eight children started ART at less than ten months of age and showed su

26 Among the 238 participants who started ART within 6 months of enrolment, the proportion

27 r who had not received previous ART and were starting ART with a CD4+ count of fewer than 100 cells p

28 an immune reconstitution-like syndrome after starting ART.

29 ingly low variability of all NMR parameters: Starting as a nucleation site for monomer-monomer contac

30 ptors, contrast adaptation has been shown to start at later stages in the retina.

31 ders (i.e., constant growth increments) that start at replication initiation.

32 Follow-up started at age 1 year, and the children were followed up

33 C4 depletion started at prodromal phase, and C4 was lowest after the

34 geniculate nuclues (dLGN) from long-term MD started at the peak of the critical period.

35 Eligible patients received oral venetoclax, starting at 20 mg per day with stepwise dose ramp-up ove

36 serial digital retinal imaging in both eyes starting at 32 weeks' postmenstrual age.

37 nd no evidence that consumption of hen's egg starting at 4 to 6 months of age prevents hen's egg sens

38 ) and relatively late in visual development (starting at 4-5 years of age).

39 compared with those fed complementary foods starting at 6 months of age.

40 eceived vehicle or BACE inhibitor (60 mg/kg) starting at 7 wk of age.

41 ients with adult-onset of asthma (defined as starting at age >/=18 years) as compared with childhood-

42 Colonoscopy every 5 years, starting at age 40 years, was the optimal colonoscopy st

43 C50 when treatment is given prophylactically starting at the time of infection.

44 with sham injections on nontreatment visits starting at week 24 was initiated on meeting prespecifie

45 Statin treatment starts at diagnosis, but no statin has been formally eva

46 ented by blocking free spaces on surface via starting block phosphate buffer saline-tween20 blocker.

47 Nonspecific binding was prevented using starting block T20 (PBS).

48 entilation occurred during the induction and start bronchoscopy following hypoventilation may decreas

49 hydroxymethyl)propionic acid and used as the starting building block for the divergent, convergent, a

50 number of antioxidants against peroxidation, started by a 2,2'-azobis[2-(2-imidazolin-2-yl)propane] r

51 the independent regulation of pre- and post-Start cell-cycle periods rather than the consequence of

52 ased on independent control of pre- and post-Start cell-cycle periods.

53 on experiments suggest that the maize zygote starts cell wall deposition within 30 seconds after fusi

54 ed cells differ quantitatively from both the starting cells and the target cells.

55 The sample included 678220 adults who started chemotherapy during the observation period.

56 Mutation of the start codon of two C-terminal ORFs in an infectious clon

57 Thus, AUG is the optimal start codon that is actively maintained by purifying sel

58 Mutation of the start codon to a sub-optimal form (GUG or UUG) tends to

59 a promoter and the 5' exon with a functional start codon while the bulk of the protein-coding sequenc

60 IF4A-dependent mechanism that utilizes a CUG start codon.

61 and diminish initiation at near-cognate UUG start codons in yeast mutants in which UUG selection is

62 Selection on start codons is most pronounced in evolutionarily conser

63 hat thousands of uORFs initiate with non-AUG start codons.

64 itch that is strongly selected against among start codons.

65 genetic distance were larger than a certain starting distance was fitted by single or multiple expon

66 ve loss-of-function polymorphisms within the START domain protein were associated with climate factor

67 OS) of patients who were prescribed standard starting dosage sorafenib (800 mg/d per os) versus that

68 nse system to receive inotuzumab ozogamicin (starting dose 1.8 mg/m(2) per cycle [0.8 mg/m(2) on day

69 There are few data examining how sorafenib starting dose may influence patient outcomes and costs.

70 that of patients who were prescribed reduced starting dose sorafenib (< 800 mg/d per os).

71 Reduced starting dose sorafenib patients had more Barcelona Clin

72 inohydantoin products from the corresponding starting E- or Z-N'-alkenyl urea, each of which may be f

73 nges in vegetation greenness) in urban areas starts earlier (start of season, SOS) and ends later (en

74 rity of the United States, whereas lightning-started fires were dominant in only 0.7 million km(2), p

75 here fuel moisture was higher than lightning-started fires, thereby helping expand the geographic and

76 In buffer, excitability starts frequently with Ras activation in the back/side o

77 We start from a sample of 143 patients characterised throug

78 ratory pressure titration (steps of 2 cm H2O starting from >/= 26 cm H2O).

79 we report the total synthesis of stolonidiol starting from (R)-(+)-limonene.

80 be obtained by a nonstereoselective approach starting from 2'-F U.

81 ent with specific GSK3 inhibitor (L803-mts), starting from 4 hours after 600 mg/kg dose of APAP, resu

82 Lactate levels in the culture medium starting from 50microM with production rates of 5microMh

83 ccount for the separation of the two domains starting from a homogeneous array of cells, and thus for

84 -alstoscholarisine B and C were accomplished starting from a readily available indole-2-acetic ester

85 Here we show that, starting from a suite of biosynthetic enzymes, catalysts

86 re we describe a medicinal chemistry program starting from amicarbalide that led to two compounds wit

87 The tricarbocyclic scaffold was assembled starting from an easily accessible A ring building block

88 sing a one-pot microwave-assisted synthesis, starting from arsenic (III) oxide.

89 e, with two or more peptides per protein and starting from as little as 200 mul of plasma.

90 tional squaramides have been easily prepared starting from diamines derived from natural amino acids

91 Starting from dimethyl (E)-2-{[(1-tert-butoxycarbonyl)-1

92 ulted in the highest bacterial load observed starting from early adulthood.

93 Starting from Planck and Einstein, several authors have

94 The third approach starting from R-mandelic acid, involving the RCM reactio

95 yliodonium reagent to generate triarylamines starting from simple anilines, representing an atom-econ

96 is of substituted indenones was accomplished starting from simple o-iodoketones and aldehydes.

97 olecule-molecule interaction strengths (i.e. starting from strong directional multiple H bonds up to

98 ients before and during patient recuperation starting from the early febrile to the defervescence and

99 Starting from the first TA synthesis in 1981, this revie

100 significant healing of erosions and plaques starting from the peripheral aspect within 1 to 2 weeks

101 Starting from the same monoboronic ester intermediates,

102 e is no bottom-up, dynamical account of how, starting from the solitary ancestor, the first groups or

103 Starting from the state-of-the-art of organosulfur ligan

104 Herein, starting from the structural similarity of a potent G4 l

105 Starting from this and in order to increase bioaccessibi

106 quiterpene quinol dasyscyphin E was achieved starting from trans-communic acid.

107 nd make consistent the HPO terms predictions starting from virtually any flat learning method.

108 Their synthesis starts from l-lactic acid-derived propargyl alcohol, whi

109 in arabinosylation in DDGS compared with the starting grains.

110 PID-RCT entered RAPID-OLE: 76 from the early-start group and 64 from the delayed-start group.

111 eeza; early-start group) or placebo (delayed-start group) in the RAPID-RCT trial were included in thi

112 A1PI treatment (Zemaira or Respreeza; early-start group) or placebo (delayed-start group) in the RAP

113 he early-start group and 64 from the delayed-start group.

114 Critical slowing down starts growing appreciably several years before the Disn

115 Behavioural and emotional problems often start in early childhood, and this might be particularly

116 an Multicenter Allergy Study, a birth cohort started in 1990.

117 n of fluid milk products and fat spreads was started in 2003 in Finland to improve vitamin D status.

118 nd that local transmission is likely to have started in the spring of 2016-several months before its

119 xceeded pay-for-performance bundled payments starting in 2008.

120 eling requirements will include added sugars starting in July 2018, but no measure currently exists t

121 Starting in May 2015, 93 cases of Zika virus disease wer

122 ension involves hierarchical representations starting in primary auditory areas and moving laterally

123 sis, led to a resurgence of interest in ArMs starting in the early 2000's.

124 had slightly lower cognitive performance and start index than SN at baseline, both groups improved on

125 All patients started induction treatment; 57 (80%) received radioimmu

126 tic memory is likely erased before parasites start infection of a new human host.

127 Starting infections with different segment combinations,

128 ere diabetic, and 91% were hypertensive; 104 started intervention, and 92 completed the 4-month study

129 PITPalpha residues conserved throughout the StART-like PITP family; and (v) conformational transitio

130 ia large-scale convection to its approximate starting location.

131 cid intermediate, derived from the arylamine starting material and CO2 in the presence of DBU, is deh

132 Molecular tools require DNA as the starting material for diagnosis, and hence, a prerequisi

133 ing different pathways and in racemizing the starting material via formation of an allyl iodide inter

134 ative increase of AX content compared to the starting material.

135 tners simultaneously, using small amounts of starting material.

136 and methods making use of biomass-accessible starting materials are also rare.

137 ks is presented using inexpensive commercial starting materials as opposed to previous syntheses of t

138 ox-active esters were found to be convenient starting materials for simple, thermal, Ni-catalyzed rad

139 neration of molecular complexity from simple starting materials is a key challenge in synthesis.

140 Moreover, various starting materials required in this protocol are easily

141 ly accessible through commercially available starting materials, enables a modular approach for the s

142 esigned from relatively low-molecular-weight starting materials, with the degree of modification cont

143 s in three steps from commercially available starting materials.

144 access 1,4-dicarbonyl compounds via umpoled starting materials.

145 ic amines from simple commercially available starting materials.

146 thylidene)oxindoles and 1,4-benzoxazinone as starting materials.

147 ubstituted porphyrins from readily available starting materials.

148 five enzymatic steps with vitamin B5 as the starting metabolite, phosphorylated by pantothenate kina

149 e effect of high energy events on a range of starting mixtures representative of various atmosphere-i

150 he early 1980s, when global surface networks started monitoring atmospheric CH4 mole fractions.

151 to determine conditions for liquid drops to start moving away from the corner of two non-parallel pl

152 After exercise, START (n = 22) had significantly lower miR-22-3p than co

153 show here that the crystal structure of the starting nanocrystals has a strong influence on the exch

154 eld, and a longer emission lifetime than the starting NCs.

155 From a starting number of 2000 atoms, 1400 atoms reach quantum

156 overall change in incidence rates since the start of a national dementia program in 2003 (-0.025; 95

157 mponents in the boundary layers indicate the start of a new cycle every time with respect to the calc

158 med, resulting in a missed diagnosis and the start of an outbreak at a New York City (NYC) university

159 onse to our protocol (published prior to the start of analysis) with qualifying unpublished data, wer

160 and fusion of Atg9 and COPII vesicles at the start of autophagosome biogenesis.

161 te (or AIDS diagnosis, if this was earlier), start of cancer registration, or Jan 1, 1996, and ended

162 Median overall survival from the start of chemotherapy was 29 months (95% CI 24-40 months

163 s; p = 0.037) and a longer delay before the start of chest compressions (109 +/- 77 vs 70 +/- 56 s;

164 tive single-center study of all LT since the start of DCD program (2001-2015).

165 months (95% confidence interval, 6-54) from start of midostaurin.

166 High concentrations of D-dimer early after start of NMP can be considered a marker of severe I/R in

167 on greenness) in urban areas starts earlier (start of season, SOS) and ends later (end of season, EOS

168 Mortality after the start of study treatment was similar in the two study gr

169 online survey; 85 [60%] female; mean age at start of study, 53 [range, 8-83] years; 131 [93%] white)

170 ates have occurred less frequently since the start of the 21st century, but civil insecurity outside

171 Our results indicate that the start of the epidemic was driven by horizontal dissemina

172 If at the start of the epidemic, sufficient vaccines had been avai

173 We used NDVI to estimate the start of the growing season (SoGS) in irrigated and non-

174 ginnings of organized surgery and the formal start of the professionalization and specialization of s

175 Doppler ultrasonography was performed at the start of the study and then at 6 and 12 months after the

176 and 2001, the years immediately prior to the start of the study.

177 for retention of the stereochemistry of the starting olefins at low conversion.

178 , emission certification standards, and cold-start on emissions.

179 Vorinostat (100 mg twice daily) was started on day -10 and continued through day +100 post-H

180 Patient was started on IV fluids and antibiotics.

181 impairment of Foxp3(+) Tregs in vivo at the start or stop of therapy impaired immune tolerance, high

182 Starting organic materials were microorganisms and organ

183 Here we start our discussion with a description of surface chira

184 covalently bonded dimers and trimers of the starting oxoacids, many of which are multi-tailed lipids

185 nal patient developed vomiting and diarrhea, started palliative care, and died 60 hours after the fal

186 unding to support this approach, but getting started, particularly at institutions that lack a robust

187 of lung density loss was reduced in delayed-start patients (from -2.26 g/L per year to -1.26 g/L per

188 ant difference was seen in the rate in early-start patients during this time period (-1.51 g/L per ye

189 r year to -1.63 g/L per year), thus in early-start patients the efficacy was sustained to month 48.

190 INTERPRETATION: Starting patients on doxycycline is non-inferior to stan

191 recisely controlled by simply modulating the starting peptide and fluorinated solvent concentrations

192 subsequently expanding over 500 km from its starting point [7-11].

193 The findings are an important starting point for clinicians considering the introducti

194 pted to other imaging modalities and forms a starting point for further steps of data analytics and m

195 lation within the spinal cord constitute the starting point for handedness, implying a fundamental sh

196 onomically verified dataset provides a valid starting point for macroecological and evolutionary stud

197 ants of plant root colonization and offers a starting point for targeted improvement of the colonizat

198 2 diabetes mellitus, as well as a promising starting point for the design of structural analogs with

199 Apelin-36-[L28C(30kDa-PEG)] provides a starting point for the development of diabetes therapeut

200 identifies a promising MMP-14 inhibitor as a starting point for the development of protein-based anti

201 haracterization and can serve as a promising starting point for the discovery of new antimelanoma the

202 -saccade process, in turn, helped to set the starting point of the next within-saccade process.

203 W. smithii provides a unique starting point to determine if there are universal nonbi

204 These studies will serve as a starting point to explore the nonlinear dynamics of atri

205 i) reconstruct theoretical haplotypes in the starting population by using clustering of single nucleo

206 differences in MI risk between patients who started PPIs vs H2RAs for the first 12 months, either in

207 A high proportion of women start pregnancy overweight or obese.

208 catheter sampling during bronchoscopy before starting probabilistic antibiotic treatment.

209 Because starting quantities of these compounds can vary widely,

210 sustainable water utilization appear to have started replenishing the aquifers in western and souther

211 ispanic, and non-Hispanic white children who started RRT between 1995 and 2011 and were followed thro

212 y-confirmed RR-TB and those reported to have started second-line treatment.

213 projecting population growth from different starting seed densities showed that seeds could replace

214 gs indicate that in prokaryotes, translation start signals are subject to weak but significant select

215 ocated downstream from SALL4 transcriptional start site (TSS).

216 n within 500 base pairs of the transcription start site and akin to its bacterial homologue NusG.

217 -loops are bounded between the transcription start site and the first exon-intron junction.

218 physically interacts with the transcription start site of ARID5B, that alleles of rs7090445 have dif

219 5 is recruited proximal to the transcription start site on the majority of transcription units, while

220 enomic region 3' of the Nkx3.1 transcription start site to be responsible for alterations in Nkx3.1 e

221 expression of an alternative transcriptional start site, including AKT3 The novel AKT3 transcriptiona

222 ome position downstream of the transcription start site, we identified unwrapped intermediates, inclu

223 Transcription start-site (TSS) selection and alternative promoter (AP)

224 n components),transcription at transcription start sites (TSS), and the number of CCCTC-binding facto

225 ssociated with a longer pol II dwell time at start sites and reduced transcriptional polarity because

226 or biased distribution towards transcription start sites in the promoters of co-expressed genes.

227 ceptibility regions with the transcriptional start sites of 304 target genes.

228 ine clusters surrounding the transcriptional start sites of expressed genes; its distribution was inv

229 referential integration near transcriptional start sites, like gammaretroviruses.

230 Our analysis of foraging's transcription start sites, termination sites, and splicing patterns us

231 in repressed regions and near transcription start sites, whereas the genetically regulated CpGs are

232 on is achieved via alternative transcription start sites.

233 were more likely to initiate smoking and to start smoking younger.

234 elevated and 12 diminished in post-exercise START, STOPP and control compared to nonexercise groups.

235 Our robust sampling, which included over 40 starting structures spanning the spectrum from the exten

236 ery short-lived intermediate was observed to start the G4 folding process in both salt conditions.

237 BMI should be systematically assessed before starting the antiviral therapy for early detection and t

238 295 (66%) were extubated within 10 hours of starting the extubation readiness test, including 272 wh

239 d anticancer therapy 14 days or fewer before starting the study, or had received previous treatment w

240 .7%) women and 2884 (23.3%) men at the study start; the mean (SD) age of these patients was 27.8 (10.

241 Of 3949 eligible participants, 16% started therapy with a statin, 11% with an ACEI/ARB, and

242 ansferase enzyme activity or genotype before starting thiopurine therapy compared with empiric weight

243 matching the effective exposure to both the start time and duration of a single molecule we diminish

244 In addition, school start times are often earlier in adolescence and the use

245 The different velocities and start times of the waves indicate a non-uniformity in th

246 ation, at shorter distances evanescent modes start to contribute, and at separations comparable to in

247 ly is removed, the amplitude of oscillations start to decay immediately, since there is no means to r

248 Moreover, the exchange bias field (HEX) started to appear at T 40 K and its value increased by d

249 ontribution from advective settings has just started to be acknowledged.

250 owed with neurosecretory cells that probably started to connect into neuronal networks soon afterward

251 over the past few decades, but scholars have started to examine medical ethics under Nazism only in r

252 ung male, selected a firm stem of grass, and started to intently remove debris from his teeth.

253 Recent studies, highlighted in this review, started to interconnect PI3K pathway activation to Ca(2+

254 human genome has plummeted, and genomics has started to pervade health care across all stages of life

255 by different human CD4(+) T cell subsets and started to unveil the potential use of their quantity in

256 for coupling DNA unwinding with synthesis is starting to be elucidated, however the architecture and

257 ive concrete examples of how this promise is starting to be realised.

258 Moreover, altered GRK2 levels are starting to be reported in different tumoral contexts an

259 earch could inspire scientists' interests in starting to focus on a new pathway instead of making hug

260 nca of web programming, these 'web apps' are starting to revolutionize and democratize scientific res

261 hat forms on the surface of the embryo as it starts to elongate.

262 transform infrared spectroscopy, that COR15A starts to fold into alpha-helices already under mild deh

263 d to the waiting list for high-intensity CBT started treatment by the end of the trial, compared to 6

264 Those who started treatment in the later cohort appeared to be mor

265 Of 77 who started treatment prior to 2013, 66 (86%) completed trea

266 ent (mean [range] age, 56 [37-78] years), 75 started treatment, and 69 completed 12 weeks of treatmen

267 ased to 10 ppm between 72 and 96 hours after starting treatment and then to 5 ppm on day 10 or 11.

268 ys after infection and RAVV-infected animals starting treatment three or six days after infection.

269 aims among propensity score-matched patients starting treatment with dabigatran or warfarin.

270 ealth problems should be dealt with prior to starting treatment.

271 The START trial was a randomised controlled trial in ART-nai

272 sted on a chassis dynamometer using the cold-start unified cycle.

273 ase biocathode CH4 production, assist in the start-up of an electromethanogenic biocathode, and/or ma

274 space, less medium consumption, and shorter start-up time.

275 The final SMH values were compared to the starting values (after 24 hr).

276 pression, sustained an unexplained fall, and started walking cautiously.

277 ratures show for many regions a cooling that started well before the EOT and continued into the Early

278 Antibiotic treatment was started when prespecified diagnostic criteria were met (

279 Human-started wildfires disproportionally occurred where fuel

280 Human-started wildfires were dominant (>80% of ignitions) in o

281 We start with optical imaging experiments on CA1 in mice as

282 ablated, as we observed that ageing in mice started with a substantial loss of these hypothalamic ce

283 A new epoch started with the discovery of head direction cells and t

284 Phase 2 started with the distinct elongation of a single sarcome

285 Here, starting with a medicinal chemistry approach, Baker et a

286 At the protein level, starting with a primitive form in cyanobacteria, RCA of

287 different clinical studies of pembrolizumab, starting with a small pilot of 19 melanoma patients and

288 reinvestigated in wine and in model solution starting with an elevated initial concentration.

289 Starting with cell encapsulation in digested lymphoid ti

290 sensus sequences can be achieved in 1-2 d by starting with clinical samples and following a simple la

291 5 was to look for mechanistic understanding, starting with examining evidence for the Top Dozen and B

292 complex spatiotemporal patterning of events starting with neural signaling molecules in the frontal

293 Starting with the 3D genome organization map of LCL, we

294 study, four jam formulations were developed, starting with the basic formulation (Jam 1) containing s

295 ep forward in improving DPT standardization, starting with the most frequently tested drugs, BL antib

296 eered molecular dynamics (CVSMD) simulations starting with the two crystal structures embedded in mod

297 d catalysis has been examined for each metal starting with zero-valent metal NPs followed by oxides a

298 This review starts with human SRA and mainly focuses on recent progr

299 HIV-1 entry into host cells starts with interactions between the viral envelope glyc

300 e flight and 3 different times after flight, starting within a few hours of return to Earth.