ライフサイエンスコーパス: start site

1 -146 to -1008 relative to the transcription start site).

2 tyrosine 88 upstream of the AR transcription start site.

3 n of genomic distance from the transcription start site.

4 kb upstream of the 12-HETER1 transcriptional start site.

5 iated from a conserved, intronic translation start site.

6 am sequence within 3 kb of the transcription start site.

7 dCas9 binding relative to the transcription start site.

8 l to and upstream of the AICDA transcription start site.

9 eosomes phased relative to the transcription start site.

10 onto mRNAs and selection of the translation start site.

11 am and 60 bp downstream of the transcription start site.

12 ind remotely upstream of the transcriptional start site.

13 located 83 kb upstream of the transcription start site.

14 around 2 kb upstream of SQSTM1-transcription start site.

15 ween Ubx enhancers and the Ubx transcription start site.

16 located upstream of the major transcription start site.

17 asis of their proximity to the transcription start site.

18 that are more proximal to the transcription start site.

19 paused RNA polymerase II downstream from the start site.

20 yielding a protein with a unique translation start site.

21 h upstream and downstream of transcriptional start sites.

22 ions and also present multiple transcription start sites.

23 ranscripts displaying intronic transcription start sites.

24 upercoiling that assists promoter melting at start sites.

25 ee regions proximal to their transcriptional start sites.

26 d loops and use of alternative transcription start sites.

27 on is achieved via alternative transcription start sites.

28 re organized with respect to transcriptional start sites.

29 ly to sites that are distal to transcription start sites.

30 which Pol II accumulates near transcription start sites.

31 relate its location to known transcriptional start sites.

32 II paused just downstream of transcriptional start sites.

33 ments via the use of alternative translation start sites.

34 omplexes to local and distal transcriptional start sites.

35 ks identified in enhancers and transcription start sites.

36 ethyl (H3K4me2) extended farther upstream of start sites.

37 We identified 248 transcriptional start sites, 116 transcriptional termination sites and 8

38 ions, 231 exon extensions, 192 novel protein start sites, 19 novel translational frames, 28 events of

39 splicing event identified was an alternative start site (39%), MBD-seq genome-wide CpG methylation da

40 ts show that OGA maps to the transcriptional start site/5' ends of genes, showing considerable overla

41 ative initiator element at the transcription start site acts as a target for negative regulation impo

42 upstream or downstream of the transcription start site allows for specific and sustainable gene-expr

43 methylation of the IGF-1 P2 transcriptional start site among IUGR lineage F2 offspring was reversed

44 regulatory domains 5' of the transcriptional start site an important regulatory domain resides in int

45 t in G4 sequence motifs at the transcription start site and 5' ends of first introns (false discovery

46 relative 5(me)C levels at the transcription start site and a decrease in the gene-body, respectively

47 n within 500 base pairs of the transcription start site and akin to its bacterial homologue NusG.

48 Core promoters encompass the RNA start site and consist of functional elements such as th

49 only with focused analyses of transcription start site and gene body regions (in contrast to when ge

50 ichment and depletion near the transcription start site and identify triplets that have the strongest

51 which, in yeast, obstructs the transcription start site and is frequently assembled with the histone

52 nds near the VEGFR2 promoter transcriptional start site and plays a role in maintaining an open confo

53 ications around the Cga gene transcriptional start site and that JNK inhibition dramatically reduces

54 -loops are bounded between the transcription start site and the first exon-intron junction.

55 ny kilobases downstream of the transcription start site and to produce invariably tight repression of

56 tment of RNA polymerase to the transcription start site and upregulation of target operons.

57 and -5550 bp ahead of the main transcription start site and via an NF-kappaB-dependent mechanism.

58 coma viral oncogene homolog) transcriptional start site and within the gene promoter region of Egr-1

59 hment of Lin28A binding around transcription start sites and a positive correlation between its genom

60 oned immediately downstream of transcription start sites and at different densities across chromosome

61 fied by ini-seq are found at transcriptional start sites and contain G-quadruplex (G4) motifs.

62 sites are located proximal to transcription start sites and correlate genome-wide with transcription

63 amma-retroviral integration to transcription start sites and enhancers through bimodal interaction wi

64 th nucleosome positioning at transcriptional start sites and expression levels of >1,000 INO80-regula

65 oned nucleosomes downstream of transcription start sites and flanking splice sites.

66 tematic study determines 3,570 transcription start sites and identifies 230 small RNAs and a consider

67 persensitive sites (DHSs) near transcription start sites and independently through 3' UTR regulation.

68 ne acetylation is increased at transcription start sites and near downstream regions.

69 We also identified transcriptional start sites and other putative regulatory regions that a

70 model in which MuvB binds near transcription start sites and plays a role in positioning downstream n

71 ssociated with a longer pol II dwell time at start sites and reduced transcriptional polarity because

72 Structural signatures at translational start sites and ribosome pause sites are conserved from

73 g 5' RACE, we identified three transcription start sites and several splice variants of ChemR23 in bo

74 rtant genomic features such as transcription start sites and splicing sites from histone marks.

75 eosome-depleted regions around transcription start sites and transcription termination sites.

76 ion of nascent transcripts accurately mapped start sites and unstable transcripts.

77 e-induced H3 K9 acetylation at transcription starting site and enhancer regions.

78 00 bases upstream of the CEBPA transcription start site, and demonstrated through mutational analysis

79 due to differences around the transcription start site, and that its expression is repressed by down

80 DNA spanning promoter region, transcription start site, and the CAG expansion mutation of the mutant

81 protein CEBPZ present at the transcriptional start site, and this is required for recruitment of METT

82 177-bp region upstream of the transcription start site, and this region did not contain any SMAD bin

83 Alternative promoters, transcriptional start sites, and mRNA splicing lead to the existence of

84 activity, and distance to the transcription start site are features of dose-sensitive CUX1 transcrip

85 omes immediately downstream of transcription start sites are anchored and recapitulates nucleosome ph

86 The majority of transcription start sites are associated with distal or inter-chromoso

87 ng transcripts (SNTs) and found that the SNT start sites are enriched with the subgroup of nucleosome

88 tend downstream of annotated transcriptional start sites are nevertheless bound by non-nucleosomal or

89 eLa cells revealed that sequences at reverse start sites are similar to those of their forward counte

90 ize, are located closer to the transcription start site, are more significant, and tend to influence

91 are cotranscribed from a major transcription start site at the -25 nucleotide (G) upstream of cps2A,

92 of the translated regions of mRNAs including start sites at single-nucleotide resolution.

93 vel ASVs from an alternative transcriptional start site (ATSS) of the MBP gene as well as a never bef

94 g transcripts that do not have a translation start site (AUG) but contain an open-reading frame for g

95 ique-5' (U5) sequence and those near the gag start site (AUG).

96 though the distribution of the transcription start sites becomes broader than that in wild-type cells

97 chanism of precise determination of the mRNA start site by Tup family corepressors and CBF/NF-Y prote

98 and chromatin gave patterns of transcription start sites closely similar to those occurring in vivo,

99 the 70 bp upstream of the AT2R transcription start site contain a core promoter region, and regions u

100 exons consistent with existing transcription start site data.

101 Annotation of 1625 transcriptional start sites defines transcription units for most protein

102 ome occluding the TATA box and transcription start sites did not impede transcription but rather, enh

103 eriments showed that alternative translation start sites direct the At5g32470 protein to the cytosol

104 ccurs primarily from alternative translation start sites downstream of the stop codon.

105 utilization of an alternative transcription start site driven by the master filamentation regulator

106 Follow-up for the latest-starting sites ended on April 1, 2014.

107 e of epigenetic marks at their transcription start sites, evolutionary conservation among other schis

108 ng nearly 2 kb upstream of the transcription start site for 68 alleles from 57 major lineages of clas

109 5' RACE indicates a transcription start site for HYDIN2 outside of the duplication and we

110 Zap1-mediated changes in the transcriptional start site for RTC4 and the production of a RTC4 transcr

111 Examination of the 5' transcriptional start site for the sat mRNA revealed two unique start si

112 of the duplex DNA and identification of the start site for transcription by RNA polymerase II.

113 ng sites enriched toward the transcriptional start sites for both induced and repressed genes.

114 T1 (TET1ALT) that has a unique transcription start site from an alternate promoter in intron 2, yield

115 q peaks for a given protein or transcription start sites from known gene models.

116 395471, 800 bp upstream of the transcription start site, gave the most significant association with H

117 n the promoter and the hCD39 transcriptional start site, generating a mouse in which the expression o

118 NAs synthesized from different transcription start sites have different functions in viral replicatio

119 ypomethylated intervals around transcription start sites have evolved to be considerably wider in pri

120 l read-through, and numerous unpredicted RNA start sites have made the analysis of vaccinia virus gen

121 ajority were located distal to transcription start sites, highlighting the importance of regions outs

122 lie within 3 kb upstream of a transcription start site in all species.

123 starting 664 bp upstream from translational start site in both, mature and senescent leaves.

124 generated via an alternative transcriptional start site in the atypical protein kinase C (PKC)zeta is

125 imethylation (H3K27me3) near transcriptional start sites in genome-wide sequencing of chromatin immun

126 tructural similarities between transcription start sites in the genomes of four Drosophila species.

127 or biased distribution towards transcription start sites in the promoters of co-expressed genes.

128 rst global annotation of the transcriptional start sites in V. cholerae and highlight the importance

129 8000 bp flanking the predicted transcription start sites in Xenopus tropicalis for genome wide identi

130 expression of an alternative transcriptional start site, including AKT3 The novel AKT3 transcriptiona

131 omes immediately distal to the transcription start site, independently of gene length.

132 colocalization of histones and transcription start sites indicate chromatin regulation of transcripti

133 sequence composition near the transcription start site influence pausing, with divergent features be

134 SON binds to DNA near transcription start sites, interacts with menin, and inhibits MLL comp

135 T gene (-51 to -33 relative to transcription start site) is essential for basal transcriptional activ

136 4 expression predominates as a transcription start site isoform encoding a cytoplasmic protein, which

137 referential integration near transcriptional start sites, like gammaretroviruses.

138 ly positioned nucleosomes near transcription start sites likely represent different states of promote

139 dent on an additional distal transcriptional start site located within the bbb23 open reading frame.

140 H3K9 immediately downstream of transcription start sites marked with H3K4me3 to establish the bivalen

141 ide identification of microRNA transcription start sites (miRNA TSSs) is essential for understanding

142 stered mutations near active transcriptional start sites; non-canonical AID (nc-AID), leading to geno

143 s, CisMapper can predict which transcription start site of a gene is regulated by a particular bindin

144 y, immediately upstream of the transcription start site of active promoters, we frequently observed n

145 physically interacts with the transcription start site of ARID5B, that alleles of rs7090445 have dif

146 element 47 kb upstream of the transcription start site of c-Myc-interacting CDCA7L.

147 binding element close to the transcriptional start site of CCL20.

148 d -13/-14 kb from the upstream transcription start site of CCR6 that bind PLZF in CCR6(+) cells.

149 or 2 (KLF2) binding near the transcriptional start site of CD39.

150 -2109 base pair relative to the translation start site of CYP2C8.

151 hat BRD4 is recruited to the transcriptional start site of differentiation-induced genes.

152 irects H4 acetylation near the transcription start site of highly expressed genes, while Eaf3 is impo

153 primers directed against the transcriptional start site of IL-6 and CXCL8 gene promoters was performe

154 over, two CpG islands near the transcription start site of MYBL1 were identified, and O-GlcNAc levels

155 s encoded 5 kb upstream of the transcription start site of MyoD, a myogenic transcription factor gene

156 ely -9400 bp upstream of the transcriptional start site of Nkx2-5, which overlapped with a previously

157 leosome depleted region at the transcription start site of pol III genes extends past the termination

158 ent of ERalpha upstream of the transcription start site of SUSD3 was demonstrated by chromatin immuno

159 ysically associated with the transcriptional start site of target genes, irrespective of target gene

160 to mutate CTCF-binding sites at the putative start site of TERRA transcripts for a class of subtelome

161 3K4) in the chromatin around the translation start site of the gene.

162 activator of transcription 3, and a putative start site of the human mIndy promoter was determined.

163 d about 170 kb upstream of the transcription start site of the major transcript for the CADM2 gene, b

164 This region contained the transcriptional start site of the most highly expressed CD16a isoform in

165 m-loop is positioned 6 nucleotides 3' of the start site of the subgenomic RNA in all caliciviruses.

166 cose-induced mRNA decay without altering the start site of transcription.

167 ceptibility regions with the transcriptional start sites of 304 target genes.

168 s is selectively targeted near transcription start sites of a small group of genes and that most H3NT

169 romatin and localizes to the transcriptional start sites of active genes.

170 oning, particularly around the transcription start sites of affected genes.

171 e chromatin landscape at the transcriptional start sites of B-cell- and T-cell-specific factors.

172 cular and biochemical approaches to identify start sites of DNA replication (origins) based on the pr

173 Start sites of DNA replication are marked by the origin

174 Around the transcription start sites of endo-MEGs, DNA methylation and H3K4me3 sp

175 e significantly co-enriched at transcription start sites of erythroid genes, and their binding was as

176 Enhancer regions and transcription start sites of estrogen-target regulated genes are conne

177 ine clusters surrounding the transcriptional start sites of expressed genes; its distribution was inv

178 hly enriched proximal to the transcriptional start sites of genes of diverse functions.

179 a maximum frequency around the transcription start sites of genes.

180 RNF2 and SALL4 together occupy transcription start sites of germline genes in the stem cell populatio

181 We also show that some transcription start sites of H3K27me3-repressed injury genes of uninju

182 Histone marks around transcription start sites of HSV-1-induced and constitutively transcri

183 at is enriched upstream of the transcription start sites of hundreds of testis-expressed genes; evolu

184 ce of Grh-binding sites to the transcription start sites of its targets.

185 regions (NFRs) associated with transcription start sites of most genes.

186 that PRDM11 associates with transcriptional start sites of target genes and regulates important onco

187 tly around 50-500 kbs from the transcription start sites of their nearby genes, and were closely loca

188 ls of 5-hydroxymethylcytosine (5hmC) at exon start sites of upregulated genes, notably axon guidance

189 erlaps the transcriptional and translational start sites of xdhABC.

190 5 is recruited proximal to the transcription start site on the majority of transcription units, while

191 rt site for the sat mRNA revealed two unique start sites, one for respiring cells that correlated wit

192 tion reveals two alternative transcriptional start sites, one of which is exclusive to heat stress.

193 enriched near CpG islands and transcription start sites (P<2.2 x 10(-16)), consistent with recent ev

194 regulatory features (40% more transcription start sites per gene, 22% longer 5'UTR).

195 act with proximal promoter and transcription start sites, potentially bypassing hundreds of kilobases

196 ides (nt) upstream of the TERT transcription start site, predominantly in the opposite transcriptiona

197 L is linked to an unannotated alternate MFN2 start site preferentially expressed in platelets.

198 Transcription start site profiling using nano-cap analysis of gene exp

199 ent spanning the human SPRY3 transcriptional start site recapitulates the endogenous Spry3-expression

200 80 bp downstream of the Lockd transcription start site reduced the entire lncRNA transcript level by

201 of plasma DNA fragments around transcription start sites reflects the expression levels of genes in c

202 istance to their corresponding transcription start site, regardless of gene length.

203 3 signal becomes confined to transcriptional-start-site regions in 2-cell embryos, concomitant with t

204 3), and downstream of the HSP1 transcription start site required for maximal yield.

205 of the H3K36 methyl mark by Set2 over their start sites results in their suppression.

206 The analysis of 7678 focused transcription start sites revealed 40% with a perfect match to the Inr

207 is therefore conducive to promoter melting, start-site scanning, and the initiation of transcription

208 Here we report a novel mechanism of start site selection in the TATA- and Initiator-less pro

209 ttle is known about the mechanism underlying start site selection, particularly from promoters lackin

210 egulation results from altered transcription start site selection.

211 he experimentally identified transcriptional start site shortens this hypothetical protein by 69 amin

212 P4RNAs exhibit transcription start sites similar to Pol II products and are featured

213 discovery of essential roles for an internal start site (SpaO) and small RNA (InvR).

214 he region upstream of the DUX4 transcription start site suppressed DUX4 mRNA expression and increased

215 plex; scanning downstream to a transcription start site; synthesis of a short transcript, thought to

216 Our analysis of foraging's transcription start sites, termination sites, and splicing patterns us

217 d upstream of the SLC13A5 gene transcription start site that are associated with regulation of PXR-me

218 ocated 60 bp downstream of the transcription start site that has been shown to bind transcription fac

219 n 1.1 kb upstream of the CK5 transcriptional start site that is necessary for P4 activation and conta

220 single KLF site near the EphA5 transcription start site that is required for KLF16 transactivation.

221 ion located close to the protein translation start site that is thought to produce a shortened, nonfu

222 n sequence regions upstream of transcription start sites, the average length of promoter regions in A

223 for mRNA context in programming translation start sites, the rate of translation elongation, and sto

224 t when targeted far from the transcriptional start site, thereby allowing high-resolution dissection

225 enomic region 3' of the Nkx3.1 transcription start site to be responsible for alterations in Nkx3.1 e

226 gets more than 10,000 lncRNA transcriptional start sites to identify noncoding loci that influence a

227 , Nup98 binds predominantly to transcription start sites to recruit the Wdr82-Set1A/COMPASS (complex

228 dy, we developed mirSTP (mirna transcription Start sites Tracking Program), a probabilistic model for

229 to target gRNAs is between the transcription start site (TSS) and 200 bp upstream of the TSS.

230 ase pairs (bp) upstream of the transcription start site (TSS) and 86% of the TFBSs are in the region

231 By mapping global transcription start site (TSS) and chromatin dynamics, we observed the

232 NA polymerase (RNAP) selects a transcription start site (TSS) at variable distances downstream of cor

233 The transcription start site (TSS) determines the length and composition o

234 binding sites (TFBSs) near the transcription start site (TSS) display tight positional preferences re

235 ompared with DNAm sites in the transcription start site (TSS) of a gene expressed in colon tissue.

236 rent positions surrounding the transcription start site (TSS) of a reporter gene fusion in Arabidopsi

237 her, Nup153 binds around the transcriptional start site (TSS) of developmental genes and mediates the

238 ac, and H3K4me3 at hundreds of transcription start site (TSS) regions and remote regulatory sites.

239 everal promoter regions affect transcription start site (TSS) selection.

240 are DNA sequences flanking the transcription start site (TSS) that help direct the proper initiation

241 stigate genome-wide changes in transcription start site (TSS) usage by Clostridium phytofermentans, a

242 lines to measure changes in transcriptional start site (TSS) usage, identifying thousands of genetic

243 ave a functional CARE near the transcription start site (TSS), but for others the CARE is downstream.

244 lobase-long region, called the transcription start site (TSS), which is upstream of the first protein

245 and nucleotide to serve as the transcription start site (TSS).

246 b upstream of the MYC oncogene transcription start site (TSS).

247 ocated downstream from SALL4 transcriptional start site (TSS).

248 island downstream from EpCAM transcriptional start site (TSS).

249 ription bubble,' and selects a transcription start site (TSS).

250 g of RNA Pol II at the Ankrd26 Transcription Start Site (TSS).

251 3 binding events occurs near transcriptional start sites (TSS) and is defined by previously character

252 le base-pair resolution map of transcription start sites (TSS) and their relative usage.

253 NA polymerase (Pol) II locates transcription start sites (TSS) at TATA-containing promoters by scanni

254 ATAC-sequencing show that the transcription start sites (TSS) of ARGs do not change with neural firi

255 ses in part through changes in transcription start sites (TSS) or cleavage and polyadenylation sites

256 HSI establishes its noncoding transcription start sites (TSS) over a defined distance from its core

257 four states span genes from transcriptional start sites (TSS) to termination sites and two contain r

258 es at ApT dinucleotides around transcription start sites (TSS) with a bimodal distribution and appear

259 n components),transcription at transcription start sites (TSS), and the number of CCCTC-binding facto

260 ry construction by analysing transcriptional start sites (TSS), CRISRPi identified 92% of core cell e

261 ed nucleosomes downstream from transcription start sites (TSS).

262 Transcription start-site (TSS) selection and alternative promoter (AP)

263 we define full inventories of transcription start sites ("TSSomes") of Escherichia coli RNA polymera

264 e RNA polymerases (PRO-seq) or transcription start sites (TSSs) (PRO-cap) genome-wide at high resolut

265 Our transcription start sites (TSSs) analysis of Saccharomyces cerevisiae

266 thylated DMCs were enriched at transcription start sites (TSSs) and in CpG islands, and depleted in t

267 n for gene regulation; namely, transcription start sites (TSSs) and polyadenylation sites.

268 promoters are associated with transcription start sites (TSSs) and validate novel RNA transcripts us

269 Transcription start sites (TSSs) are bordered by a small nucleosome-de

270 and histone methylation around transcription start sites (TSSs) are highly coordinated with distincti

271 ational identification of gene transcription start sites (TSSs) can provide insights into the regulat

272 to derive new alternative mRNA transcription start sites (TSSs) is also evident at closely spaced pro

273 otide resolution the divergent transcription start sites (TSSs) near mouse mRNA genes.

274 eas RNA polymerase II (Pol II) transcription start sites (TSSs) occur about 30-35 bp downstream of th

275 t DSBs are enriched around the transcription start sites (TSSs) of active genes.

276 ork to examine the genome-wide transcription start sites (TSSs) of the psychrophilic methanogen Metha

277 n practice, variants near gene transcription start sites (TSSs) or certain histone modifications are

278 g genome locations relative to transcription start sites (TSSs) or enhancer midpoints, our analyses s

279 hancer" of Tet1, there are two transcription start sites (TSSs) with different activation patterns du

280 romoting the identification of transcription start sites (TSSs).

281 f transcriptional machinery at transcription start sites (TSSs).

282 some cases mutually exclusive transcription start sites (TSSs).

283 ls, but do not robustly detect changes in 5' start-site use.

284 se determinants of this noncanonical rrnB P1 start site using biochemical and genetic approaches incl

285 in immunoprecipitation and the transcription start site was identified by 5' RACE (rapid amplificatio

286 An active secondary transcription start site was identified within the intergenic region o

287 ome position downstream of the transcription start site, we identified unwrapped intermediates, inclu

288 n the algZ coding region, and two additional start sites were identified upstream of the algZ coding

289 observed within 1 kb from the transcription start site, where both histone H3 methylation marks co-o

290 trong Set1 enrichment near the transcription start site, whereas Set2 was distributed along pre-mRNAs

291 in repressed regions and near transcription start sites, whereas the genetically regulated CpGs are

292 immediately upstream from the transcription start site, which is sufficient to mediate the effects o

293 in detail and have defined its transcription start site, which our data suggest is positioned by a we

294 us cis-element upstream of the transcription start site, which was previously identified as a binding

295 tant strain identified 7,240 transcriptional start sites with approximately 47% initiated in the anti

296 rotein or CD40L) upstream of the translation start site within exon 1 allowed transgene expression to

297 tected usage of an alternative transcription start site within intron 1 of the PRTN3 gene locus that

298 is produced through an internal translation start site within the endolysin gene.

299 These occur in the vicinity of transcription start sites, within gene bodies, and in intergenic regio

300 d to 600 bp long relative to the translation start site without affecting expression.