ライフサイエンスコーパス: starting material

1 tners simultaneously, using small amounts of starting material.

2 ative increase of AX content compared to the starting material.

3 which uses unfractionated human PBMCs as the starting material.

4 the biological space of the natural product starting material.

5 posites by using low-cost SiO or SiO2 as the starting material.

6 s from a single 2-trichloromethylbenzoxazole starting material.

7 20% overall yield from a readily accessible starting material.

8 ient enantioselective synthesis from achiral starting material.

9 bond in the [Cp*Ir(NHC)Me(CD2Cl2)][BAr(F)4] starting material.

10 urea derivatives using D-glucosamine as the starting material.

11 at is the precursor for dinuclear dinitrogen starting material.

12 nsitivity, reduced analysis time, and minute starting material.

13 uires high-quality genomic DNA (gDNA) as the starting material.

14 4-aryl migration, and desulfonylation of the starting material.

15 that can be easily separated from unreacted starting material.

16 ds of iron(I) products from the iron(II/III) starting material.

17 ides, are described using 5-methyluridine as starting material.

18 from the nano- to microscale, using a single starting material.

19 ding enantioenriched enaminone and recovered starting material.

20 m, using chemically expanded graphite as the starting material.

21 pplications that demand a large(r) amount of starting material.

22 DDGS is consistently uniform irrespective of starting material.

23 t time in only 18 steps from a simple olefin starting material.

24 ry and quaternary centers from simple alkene starting materials.

25 e pi-systems might be accessible from simple starting materials.

26 onalized heterocycles from readily available starting materials.

27 les in two steps from commercially available starting materials.

28 access 1,4-dicarbonyl compounds via umpoled starting materials.

29 iently on a multigram scale from inexpensive starting materials.

30 lass of heterocycles from readily accessible starting materials.

31 ields in 3 steps from commercially available starting materials.

32 an in four steps from commercially available starting materials.

33 ic amines from simple commercially available starting materials.

34 equence of nine steps from readily available starting materials.

35 thylidene)oxindoles and 1,4-benzoxazinone as starting materials.

36 bearing adjacent stereocenters from achiral starting materials.

37 tained as the major product depending on the starting materials.

38 times, good to excellent yields, and simple starting materials.

39 ders, can be supplemented with lower-quality starting materials.

40 and easily prepared from simple, inexpensive starting materials.

41 complex aromatic compounds from preoxidized starting materials.

42 t linear sequence) from simple pyrrole-based starting materials.

43 r the synthesis of aryl sulfones from simple starting materials.

44 ndered by the requirement of large amount of starting materials.

45 of specific functional groups within complex starting materials.

46 omerization in cyclopentene and cycloheptene starting materials.

47 6%, and it tolerates structural diversity of starting materials.

48 ionalities and applicable to a wide range of starting materials.

49 targets uses inexpensive and easily obtained starting materials.

50 to a diverse range of structures from simple starting materials.

51 ulting scaffold using commercially available starting materials.

52 nomic synthesis, from commercially available starting materials.

53 ally available fluorophores and diamino acid starting materials.

54 e-bound oligotriazole catalysts from simpler starting materials.

55 so include safety issues and availability of starting materials.

56 tron-poor aryl methyl ketones can be used as starting materials.

57 rally complex heterocycles from simple amide starting materials.

58 e of difluorooxindoles from readily prepared starting materials.

59 17 linear steps) from commercially available starting materials.

60 tively prepared in good yields from the same starting materials.

61 copic complexes from inexpensive hydrated RE starting materials.

62 reaction conditions using readily available starting materials.

63 ed yields of allylsilanes from simple alkene starting materials.

64 ded chiral amines from simple and accessible starting materials.

65 properties, produced from readily accessible starting materials.

66 azoles upon activation, which cannot consume starting materials.

67 sities as high as 900 times greater than the starting materials.

68 red by labor-intensive synthesis of required starting materials.

69 n only two steps from commercially available starting materials.

70 in a single step from commercially available starting materials.

71 on mode strongly depends on the structure of starting materials.

72 and organocatalysts, from readily available starting materials.

73 ubstituted porphyrins from readily available starting materials.

74 g furan and Cbz-protected glycol aldehyde as starting materials.

75 optimizations from comparatively inexpensive starting materials.

76 powders of tantalum or niobium (20 vol.%) as starting materials.

77 s in three steps from commercially available starting materials.

78 ated nucleobases or nucleobase precursors as starting materials.

79 able carbonyl compounds from easily accessed starting materials.

80 l-substituted chiral aziridines from achiral starting materials.

81 cope from abundant and complex aryl chloride starting materials.

82 requisite trifluoromethyl-substituted alkene starting materials.

83 col was generated in 4 steps from commercial starting materials.

84 er and readily available indole analogues as starting materials.

85 3 in seven steps from commercially available starting materials.

86 vailable amines, anilines, and bisphenols as starting materials.

87 from inexpensive and commercially available starting materials.

88 ed in high yield from commercially available starting materials.

89 reverse proton transfer (RPT) to regenerate starting material; (2) addition of hydroxylic solvents t

90 heories of the area, 2) covers all-important starting materials, 3) surveys contemporary ligand class

91 45, 33 and 44%, respectively, from a common starting material 5.

92 n the ability to access the seemingly simple starting material, 6-methoxytryptophan.

93 ected 4-(allylaminomethyl)-2(5H)furanones as starting materials, a photochemical approach is presente

94 ctants which can be prepared from wood-based starting materials according to the principles of xyloch

95 s operationally simple and involves low-cost starting materials affording products in good to excelle

96 Using fluorinated starting materials, after mesylation, allowed for the de

97 gand provides nearly complete suppression of starting material alkene isomerization that was observed

98 ucted from two classes of commonly available starting materials, alkenes and carbon-hydrogen (C-H) bo

99 ile methodology, involving readily available starting materials, allows for the synthesis of stable h

100 ich a chiral Pd catalyst merges three simple starting materials-an organolithium, an organoboronic es

101 tide stereotriads from the same alpha-chiral starting material and avoids potentially epimerizable al

102 is challenging owing to decomposition of the starting material and catalytic intermediates.

103 cid intermediate, derived from the arylamine starting material and CO2 in the presence of DBU, is deh

104 eton from racemic butadiene monoepoxide as a starting material and its application to the total synth

105 mplex oligomeric catalysts both racemize the starting material and select one enantiomer for a highly

106 tive for OER than the disordered gamma-NiOOH starting material and that previous reports of increased

107 bular level of dispersions, were used as the starting material and the 3D-NDP-ACMs were obtained via

108 or a stable monofunctional intermediate-only starting material and the difunctional product have been

109 idly builds molecular complexity from simple starting materials and cannot be accomplished with high

110 fficiently assembled using readily available starting materials and conjugated to ASOs using a soluti

111 In this work, we utilized (15)N-labeled starting materials and continuous high-sensitivity (1)H-

112 ional preparation of benzamides using simple starting materials and easy-to-handle Ni catalysts.

113 ACPs have a central role in transporting starting materials and intermediates throughout the fatt

114 The reaction uses readily available starting materials and is operationally simple, thus rep

115 The use of readily accessible chiral starting materials and lactone-lactone rearrangement are

116 ct shock recovery experiment to simulate the starting materials and shock conditions associated with

117 modular approach uses commercially available starting materials and simple chemical transformations.

118 respect to both the alkyne and the quinoline starting materials and the products are easily transform

119 a]quinoxalinones from commercially available starting materials and their use in preparing potential

120 lative to their constituent olefin and amine starting materials and thus are not accessible via direc

121 red in multigram quantities from inexpensive starting materials and without costly purification proce

122 The existing reports using expensive starting materials and/or superstoichiometric metal salt

123 convenient exploitation of native IgG as the starting material, and a well-defined conjugation site f

124 dification levels, requires large amounts of starting material, and involves tedious processing of ea

125 there is a kinetic resolution of the racemic starting material, and its magnitude is correlated with

126 GO (rGO) that are fragmented compared to the starting material, and low molecular-weight (LMW) specie

127 time-consuming fabrication techniques, toxic starting materials, and large strain hysteresis under de

128 8)F, can now be accomplished from phenols as starting materials, and provides access to (18)F-labelle

129 few synthetic steps, inexpensive commercial starting materials, and straightforward reaction conditi

130 The activity, stability, low cost of starting materials, and straightforward synthesis make a

131 different from the biological profile of the starting material are presented, demonstrating that this

132 and methods making use of biomass-accessible starting materials are also rare.

133 allic compound), and the available anhydrous starting materials are also surveyed.

134 s, respectively, from commercially available starting materials are described.

135 action was found to be very general, and the starting materials are easily accessible.

136 ges: it uses a wide range of primary amines, starting materials are easily available, it is simple to

137 The starting materials are readily available, and products a

138 is limited by the behaviour of common boron starting materials as archetypal Lewis acids such that c

139 ks is presented using inexpensive commercial starting materials as opposed to previous syntheses of t

140 e 8-, 9-, and 10-membered macrocyclic lactam starting materials as well as certain bicyclic amino aci

141 roups (67-84% yields from a common hydantoin starting material) as well as a spiroligomer trimer 25 w

142 p from aminoboronic esters, which are simple starting materials available on the gram scale.

143 A new starting material-based synthesis of alpha,beta-unsatura

144 ated Z-products from easily accessible diene starting materials bearing a Z-olefin moiety.

145 functionalization, alkenes are an attractive starting material because of their abundance and low cos

146 overall synthetic approach stems from chiral starting material benzyl (S)-2-methyl-4-oxopiperidine-1-

147 ly unlimited commercial catalog of available starting materials bodes well for its rapid adoption.

148 temperature from the commercially available starting materials BrCN or ClCN.

149 ational predisposition of the anthranilamide starting material brings the aryl rings into proximity a

150 en centers, all used marrow aspirates as the starting material, but no two centers used the same manu

151 on has circumvented the need for preoxidized starting materials, but this approach is limited by a la

152 hese HTMs are obtained from relatively cheap starting materials by adopting facile preparation proced

153 easily prepared from commercially available starting materials by cross-coupling reactions, many des

154 structural complex oligosilanes from linear starting materials by Lewis acid induced skeletal rearra

155 olving initial 2e(-) oxidation of the Ni(II) starting materials by the F(+) transfer reagent N-fluoro

156 ate that the initially published quantity of starting material can be scaled down orders of magnitude

157 eries of simple and unbiased aliphatic amine starting materials can be oxidized to value-added ketone

158 collection to quantification), requires less starting material compared with standard biochemical fra

159 des better mixing and easier handling of the starting materials, consequently leading to faster react

160 torage, all six urine samples from different starting materials converged to these characteristics.

161 Also, 4-bromophenyl-substituted starting materials could be applied successfully in the

162 nsive, renewable, and environmentally benign starting materials, coupled with the tunability of their

163 The starting material, crystalline PtNi3 polyhedra, transfor

164 r unprotected nucleosides can be used as the starting material, depending on the nature of the reagen

165 itic carbon nitride derived from inexpensive starting materials (dicyandiamide and CoCl2 ).

166 ic rRNA, including those with low amounts of starting material (e.g. 100 ng).

167 The combination of inexpensive starting materials, ease of ring-closure and subsequent

168 eatures inexpensive and easily synthesizable starting materials, easy operations, and a high efficien

169 emplates as instructions to a mixture of all starting materials elicits system-level behavior.

170 ly accessible through commercially available starting materials, enables a modular approach for the s

171 an imide derived from L-tartaric acid as the starting material, ent-erysotramidine was synthesized fo

172 action of insoluble-bound phenolics from the starting material (experiment I) or the residues contain

173 4-aryl migration, and desulfonylation of the starting material explains the regioselective formation

174 ods to synthesize chiral allenes from chiral starting materials, fewer methods exist to directly synt

175 Molecular tools require DNA as the starting material for diagnosis, and hence, a prerequisi

176 term maintenance and efficient production of starting material for SSC culture.

177 The enantiopure starting material for the rearrangement step was accesse

178 ion of 1,6-diol was found to be a convenient starting material for the synthesis of aminocyclitols an

179 When aromatic ketones were used as the starting materials for Lewis acid-mediated cyclizations,

180 Dienes are ubiquitous and easily synthesized starting materials for organic synthesis, and alkyl acry

181 ox-active esters were found to be convenient starting materials for simple, thermal, Ni-catalyzed rad

182 This makes them invaluable as starting materials for syntheses of complex molecules, h

183 ped a synthetic route to mixed dianilides as starting materials for the N-N coupling.

184 principle represent attractive and abundant starting materials for the preparation of substituted cy

185 ,3-Dien-5-ynes have been extensively used as starting materials for the synthesis of a wide number of

186 Chiral LLB-A products might become suitable starting materials for the total synthesis of natural pr

187 ts, inexpensive catalysts, and user-friendly starting materials has made these methods interesting fr

188 erovskite thin films; however, the inorganic starting materials have been limited to halide-based ani

189 d with (N-ethoxythiocarbonyl)urethane as the starting material, heterocyclization to the putative "Dt

190 Depending on the substitution pattern of the starting material, high diastereoselectivity was observe

191 events in one pot starting from inexpensive starting material in ambient reaction conditions.

192 phopeptide enrichment techniques and require starting material in the milligram range, as a consequen

193 ared in 15 steps from commercially available starting materials in 6% overall yield.

194 sized from readily available and inexpensive starting materials in 63% yield over two steps.

195 oor functional groups from readily available starting materials in a more efficient manner.

196 g heterocycles by simply mixing three common starting materials in EtOH in the presence of 20 mol % N

197 roup 14 elements are well-known as versatile starting materials in many chemical transformations, a h

198 y, which actually makes aryl iodides popular starting materials in many photo-substitution reactions.

199 ly available substituted phenols are used as starting materials in the reaction sequence composed of

200 application of chalcogenophenes obtained as starting materials in the Suzuki, Sonogashira, and Ullma

201 mple tertiary alkyl amines cannot be used as starting materials in these protocols.

202 from a single fractionation protocol (2g MD starting material), including solvent partitioning throu

203 eloped herein utilizes entirely bench stable starting materials, including organotrifluoroborates, en

204 ess accessible and unpleasant arenethiols as starting materials, instead utilizes very stable aryl ha

205 on--involves the transformation of a racemic starting material into a single enantiomer product, with

206 oconvergent mechanism transforms the racemic starting material into a single product enantiomer.

207 as necessary to fully transform the benzylic starting material into the corresponding bromide.

208 n, this reactivity feature transforms alkene starting materials into a diverse array of chiral produc

209 converting these readily available prochiral starting materials into highly enantiomerically enriched

210 The starting material is easily accessible from commercially

211 rearrangement, the THF bound to the neutral starting material is expelled, and the Fe-Fe distances w

212 implicity: no prefunctionalization of either starting material is required, the reaction is insensiti

213 Moreover, the required amount of starting material is so low that RNA from fewer than 50

214 neration of molecular complexity from simple starting materials is a key challenge in synthesis.

215 erences accurately, using the same amount of starting materials is essential.

216 ynthetic value from inexpensive and abundant starting materials is of great importance.

217 cal products and their synthesis from simple starting materials is of great interest.

218 Thorough mixing of the starting materials is the first step of a crystal growth

219 vantageously maintains the morphology of the starting material, is stable against reaggregation and c

220 Employing the industrially attractive starting material isobutanal, a chemoenzymatic three-ste

221 ology is extended to the parent aldehydes as starting materials, leading to the corresponding aldols

222 onal preference of the tertiary amide in the starting material leads to intramolecular migration of a

223 s of DNA for sequencing, the small amount of starting material must be amplified significantly.

224 A major advantage is that the starting materials need not have ortho functional groups

225 The method resulted in <40% loss of starting material, no detectible ex vivo aggregation of

226 However, with only metallic starting materials, numerous micron-sized five-component

227 Unlike starting material obtained by chemical synthesis or dire

228 involved a 12,13-olefinic methyl ketone as a starting material obtained by ozonolytic cleavage of epo

229 e quantitative cellular metabolomics using a starting material of 10000 cells.

230 providing a tool to investigate the genetic starting material of crocodilians, birds, and dinosaurs.

231 nthesized easily from commercially available starting materials on a multigram scale and are self-act

232 e applied to biological samples with limited starting material or low-abundance cytosine modification

233 processes involving amidoborane compounds as starting materials or intermediates are discussed, along

234 When the starting material possesses a single activated hydrogen,

235 The geometries and energies of all starting materials, products, intermediates, and transit

236 tional group tolerance and easily accessible starting materials provide an efficient protocol for the

237 matic digestion or ligation, requires little starting material, provides high-quality data, has excel

238 syn-(ab)2-PBA 19) were explored as universal starting materials providing access to any desired imide

239 synthesis of hippolachnin A from the unusual starting material, quadricyclane, by harnessing the powe

240 -position of the benzoxazoles using the same starting materials/reagents.

241 Moreover, various starting materials required in this protocol are easily

242 range of functional groups, easily available starting materials, simple operation, mild reaction cond

243 The synthesis reported herein employs starting materials solely derived from wood.

244 tailed information on method of manufacture, starting material source, and final product, all critica

245 y and basicity, through detailed analyses of starting material spectroscopy, addition stereopreferenc

246 Six different classes of key starting materials such as hydroxamic acids, N-hydroxy c

247 fused heterocycles were accessed from simple starting materials such as nitroolefins and 3-ethoxycarb

248 As inexpensive and versatile starting materials, such compounds continue to influence

249 entration can be manipulated by altering the starting materials, synthesis conditions, and post-synth

250 d in three steps from commercially available starting materials, systematically exploring a typically

251 ine pair versus N,N-dialkyl aryl O-carbamate starting materials, temperature, solvents, electrophiles

252 scales, uses substantially greater volume of starting materials than conventional ChIPs to achieve hi

253 es the use of Be(x)Zn(1-x)O (BZO) alloy as a starting material that ultimately yields the required co

254 access to fluorinated alkanes from a pool of starting materials that are ubiquitous in nature, little

255 They serve as valuable starting materials that can be transformed into a vast a

256 ng of chemical warfare (CW) agents and their starting materials that may be implicated in chemical at

257 ed a nitrile (53%, or 85% based on recovered starting material) that was converted to the eneimide 57

258 the formed E radical anion to the neutral Z starting material the overall transformation is catalyti

259 source, the nature of the graphite (used as starting material), the potassium concentration in the i

260 th a protected glutamic acid derivate as the starting material, the process readily delivered the Fmo

261 The involvement of readily available starting materials, the broad scope, and the use of a su

262 molecular complexity from relatively simple starting materials; these transformations are particular

263 using B(9)-bromo-meta-carborane as the sole starting material through substrate control.

264 d acetone was achieved when stirred into the starting material to a final concentration of 70%.

265 Rice bran was used as a starting material to prepare protein concentrate through

266 1,5-dihydro-2H-pyrrol-2-one (13) as a single starting material to provide hybrubin A in three steps f

267 xidative N-prefunctionalization of the amide starting materials to achieve efficient amidyl generatio

268 ep- and time-economical conversion of simple starting materials to complex and thus value-added targe

269 e adapting them to different two-dimensional starting materials to create structures from the macro-

270 that natural products can serve as powerful starting materials to generate drug substances with nove

271 cence by using chicken egg white proteins as starting materials to react with aqueous tetrachloroaura

272 substituted triazenes were less reactive as starting materials toward the carbonylative annulation r

273 -a-plate format using commercially available starting materials under aqueous conditions.

274 rly difficult to access, irrespective of the starting materials used, but that these difficulties can

275 ncies (TOF) regardless of the quality of the starting materials used.

276 n of the remaining enantiomerically enriched starting material using a chiral ligand with the opposit

277 tly digested milligram amounts of protein as starting material using in-solution digestion protocols

278 ities and enantioselectivities from the same starting materials using a tandem inverse-electron-deman

279 through the semisynthetic derivatization of starting material via chemoselective acylation of the l-

280 ing different pathways and in racemizing the starting material via formation of an allyl iodide inter

281 pletely digested or barely detectable if the starting material was at 250 ng/mul.

282 The starting material was naturally contaminated Wels catfis

283 ere), the reaction did not proceed, and only starting material was recovered.

284 nated graphene (phG) produced from different starting materials were fully characterized in terms of

285 te with potassium intercalation compounds as starting materials were investigated in depth.

286 patterns, consistent with the nature of the starting materials, were obtained.

287 human tissue samples containing picograms of starting material, which is an order of magnitude less m

288 increases the library complexity per unit of starting material, which makes it feasible and cost-effe

289 changes of mutants require a large volume of starting materials, which is difficult for unculturable,

290 ion of enynones readily available from cheap starting material with pyrazolamines provides easy acces

291 products to polymers, and represent an ideal starting material with which to forge new connections.

292 ears to be heading in the direction of using starting materials with a significantly lower degree of

293 nhibitor has been achieved using inexpensive starting materials with excellent step-economy at low ca

294 r alkylamines) from readily available alkyne starting materials with high levels of chemo-, regio- an

295 and ketohexoses from common and inexpensive starting materials with high yield and purity and withou

296 in 2 to 4 steps from commercially available starting materials with minimal purification.

297 esigned from relatively low-molecular-weight starting materials, with the degree of modification cont

298 tive was shown to generate enantiopure amine starting materials without racemization.

299 te phospholipid membranes from water-soluble starting materials would be a powerful tool for generati

300 periments have been studied using ketones as starting materials, yielding both the (R)- and (S)-amine