ライフサイエンスコーパス: stasis

1 erms and tended to be retained in evolution (stasis).

2 s- or aberrant signaling-induced senescence (stasis).

3 imposed on a low underlying basal rate (near-stasis).

4 o hypoxia, inflammation, and lymphatic fluid stasis.

5 urst of diversification followed by extended stasis.

6 ures (e.g. ribosomal dimers) upon entry into stasis.

7 icularly when characterized by morphological stasis.

8 ignore the growth arrest signals produced by stasis.

9 ventually leading to a paucity of genes, and stasis.

10 suggesting a persistence mechanism via cell stasis.

11 er time to cause morphological evolution and stasis.

12 amma-mediated activation of p21-induced cell stasis.

13 nd anorexia associated with gastrointestinal stasis.

14 cence-associated beta-galactosidase-positive stasis.

15 f both pathways is required to achieve tumor stasis.

16 indicate a remarkable degree of evolutionary stasis.

17 mechanisms proposed to explain evolutionary stasis.

18 ided nearly equally between random walks and stasis.

19 models: directional change, random walk, and stasis.

20 less likely than shape traits to experience stasis.

21 TAE and TRIP MR imaging were repeated until stasis.

22 zed form of cell cycle arrest termed S-phase stasis.

23 pansions interspersed among periods of range stasis.

24 may improve bile flow and reduce gallbladder stasis.

25 ion in different cell types does not promote stasis.

26 , recurrent UTI, hypercalciuria, and urinary stasis.

27 in renal artery to achieve complete arterial stasis.

28 ocirculatory disease, and interstitial fluid stasis.

29 logical observation of faunawide coordinated stasis.

30 nts, after prolonged fasting and gallbladder stasis.

31 ing complement, and causing microcirculatory stasis.

32 l death compared to wild-type mice upon milk stasis.

33 y intervals in which the carbon cycle was in stasis.

34 nvolved in feeding behavior and energy homeo stasis.

35 contribute to the occurrence of evolutionary stasis.

36 duce thrombosis risk because of reduced flow stasis.

37 (P<0.043) reduced LA velocities and elevated stasis.

38 es with WFI is associated with a low rate of stasis.

39 fibril growth are interrupted by periods of stasis.

40 biology, would evidence extreme evolutionary stasis.

41 ascending slopes and hence, escape adaptive stasis.

42 n in critical illness due in part to gastric stasis.

43 though unmodified oxyhemoglobin exacerbated stasis.

44 osts and was not maintained in environmental stasis.

45 ies of steps followed by periods of relative stasis.

46 /kg QD is well tolerated and results in near stasis (92% TGI) in an HCT116 mouse xenograft model.

47 In concert with the stasis, a dose-dependent tumor growth delay was observed

48 eding head injury is associated with gastric stasis, a symptom of collapse of autonomic control of th

49 Cellular stasis, also known as telomere-independent senescence, p

50 flow in the normal range: 25%/68% for LA/LAA stasis and 38%/60% for LA/LAA peak velocities.

51 ing to ASL dehydration, which promotes mucus stasis and a failure of mucus clearance, leaving smokers

52 latelet adhesion and aggregation during hemo stasis and arterial thrombosis.

53 itrergic pyloric inhibition leads to gastric stasis and bezoars.

54 protein-folding reservoir might promote both stasis and change.

55 HMEC that escape stasis and continue to proliferate become genomically un

56 es that are implicated in the loss of tissue stasis and corneal clarity after injury.

57 prothrombotic milieu characterized by blood stasis and endothelial dysfunction.

58 the range edge, from rapid spread to border stasis and even retraction, highlight future opportuniti

59 ting TLR4 dependency, UP-LPS-induced gastric stasis and ileus of TLR4(WT) mice were absent in mutant

60 in causing functional UP-LPS-induced gastric stasis and ileus.

61 node (RPLN) metastases that may cause venous stasis and increase the risk of VTE development.

62 volume, which is predicted to initiate mucus stasis and infection.

63 d 458 nm thresholds, light microscopy showed stasis and inflammatory infiltrate in the papillary derm

64 n 3 days when VEGF was switched off, showing stasis and luminal occlusion, influx of inflammatory cel

65 Relative arterial stasis and near abolition of t-PA release will strongly

66 oduct carbon monoxide or biliverdin inhibits stasis and NF-kappaB, VCAM-1, and ICAM-1 expression.

67 that TGFbeta3 induction is regulated by milk stasis and not by the circulating hormonal concentration

68 Relative stasis and occasional rapid subclone growth may characte

69 to interact with RAS causes long-term tumor stasis and partial regression.

70 ht be a useful strategy for inducing S-phase stasis and promoting the radiosensitization of checkpoin

71 involution occurred in the presence of milk stasis and STAT3 activation, indicating that neither is

72 caused a dose-dependent biphasic blood flow stasis and vascular hyperpermeability, as determined by

73 Anatomic maps of LA and LAA stasis and velocity were calculated to quantify atrial p

74 ly lead to replication fork collapse, growth stasis and/or cell death.

75 These effects lead to tumor cell stasis and/or death.

76 ns that deplete ASL volume and produce mucus stasis, and (b) potential shear stress-dependent therapi

77 Opiliones epitomize morphological stasis, and all known fossils have been placed within th

78 nd decreases NF-kB activation, microvascular stasis, and mortality in transgenic sickle mouse models.

79 tial compression devices to minimizes venous stasis, and optimize intravascular volume to minimize th

80 joint disease, urinary incontinence, venous stasis, and pseudotumor cerebri.

81 A methylation step coincides with overcoming stasis, and results in few to hundreds of changes, depen

82 Virchow's triad: hypercoagulability, venous stasis, and vascular damage; together these factors lead

83 the underlying causes of niche lability vs. stasis are poorly understood.

84 ring a stress-associated senescence barrier (stasis) associated with elevated levels of cyclin-depend

85 d regarding the link between venous valvular stasis-associated hypoxia and thrombosis.

86 R2 ADCs in Founder 5 was observed with tumor stasis at 0.5-1 mg/kg, 1 mg/kg, and 3-6 mg/kg for 6, 8,

87 Tumor stasis at 2 mg/kg was observed for anti-CD22 6 in WSU-DL

88 how a remarkably high degree of evolutionary stasis at the levels of nucleotide sequence, gene synten

89 ological staining of CD31 confirmed vascular stasis at various time points post-PDT (post photodynami

90 The evolutionary stasis between influenza virus and its natural host may

91 ycER via 4-OHT deprivation resulted in tumor stasis but only partial regression.

92 mic intervals are not periods of hemodynamic stasis but, rather, phases with dynamic changes in intra

93 regained aggressive growth after a period of stasis, but interestingly, without re-expression of Delt

94 of these afferents presumably causes gastric stasis by activating downstream NST neurons that, in tur

95 Also, endotoxin may lead to gallbladder stasis by decreasing gallbladder contractile responses t

96 data suggest that S. aureus likely undergoes stasis by protecting selective mRNA with RNA-binding pro

97 Ependymal ciliary stasis by purified pneumolysin was also blocked by the a

98 These results show that stasis can be achieved without good levels of adaptation

99 n here allows recognition that morphological stasis can be the dominant evolutionary pattern within s

100 ons in red cell flux, as opposed to vascular stasis, can cause temporal variations in pO2 that extend

101 Regions of hemodynamic stasis caused by major luminal irregularities may lead t

102 mpair airway hydration, leading to the mucus stasis characteristic of both cystic fibrosis and CB.

103 r in the microcirculation, it is likely that stasis contributes to thrombotic risk, due in large part

104 Only erythrocyte aggregation at stasis correlated significantly with current CD4+ T-lymp

105 h Red-Queen type of continuous evolution and stasis could result from a model with biotically driven

106 Early stasis (defined as slowed antegrade flow, before total v

107 lly induced weight loss corrected the venous stasis disease in almost all patients as well as their o

108 The GBP database was queried for venous stasis disease including pretibial venous stasis ulcers,

109 ly more frequent in the patients with venous stasis disease than for those without.

110 Severe venous stasis disease was associated with a significantly great

111 ciated with a risk of lower extremity venous stasis disease, pretibial ulceration, cellulitis, and br

112 in patients who underwent GBP without venous stasis disease.

113 , coupled with a tendency toward gallbladder stasis (due to the absence of CCK-induced contraction),

114 lies most models for both anomalous climatic stasis during the mid-Proterozoic and extreme climate pe

115 f viral evolution, with periods of antigenic stasis during which genetic diversity grows, and with ep

116 Stasis DVT demonstrated that the highest FDG signal occu

117 ar veins and also a novel model of recurrent stasis DVT in mice.

118 rwent ligation of the jugular vein to induce stasis DVT.

119 d pathways, and reformulation of the radical-stasis equations.

120 untreated animals (P<0.001), and blood flow stasis eventually ensued.

121 provide evidence of over 3,000 y of dietary stasis followed by a decline of ca. 1.8 per thousand in

122 y phylogenetic distribution, with periods of stasis followed by bursts of loss in certain lineages.

123 ng with the predominant mode of evolutionary stasis for courtship behavior and morphology.

124 ition of a sophisticated behavioral suite in stasis for over 110 million years and an ancient plant-i

125 s, provide a remarkable case of evolutionary stasis for since the chimpanzee-human split c.8 Ma among

126 consistent with their relative morphological stasis for the past 165-200 million years.

127 sceptibility is commonly ascribed to urinary stasis from elevated residual urine volumes.

128 ing Ulp1 and subsequently affect sumoylation stasis, growth, and DNA repair.

129 rowth of genomically stable multilineage pre-stasis HMEC populations can greatly enhance experimentat

130 the properties of growing and senescent pre-stasis HMEC with growing and senescent post-selection HM

131 Thus, the effects of blood flow stasis, hypercoagulability of blood, and the characteris

132 divergences consistent with the morphologic stasis hypothesis than for a more recent radiation.

133 uantum evolution separated by nearly 3 Gy of stasis; I discuss their nature and causes.

134 Analogue 10 demonstrated complete tumor stasis in a Met-dependent GTL-16 human gastric carcinoma

135 deep veins of the lower limb and preventing stasis in a variety of subject groups.

136 an volume, 0.25 mL +/- 0.09) led to complete stasis in all kidneys.

137 mportance of desiccation, longevity and cell stasis in basic microbiology, and the relevance of the t

138 been associated with increases, decreases or stasis in body size in different populations.

139 Improved understanding of the role of mucus stasis in causing bacterial colonization has led to incr

140 nce and exit limbs into the hernia (n = 17), stasis in clustered bowel (n = 16), densely matted bowel

141 was not generally accompanied by decline or stasis in cropland area at a national scale during this

142 ents occurred initially, followed by extreme stasis in gene order and slow decay of additional genes.

143 This finding of extreme stasis in genome architecture, also reported previously

144 n morphological evolution is associated with stasis in genome evolution.

145 Many putative examples of evolutionary stasis in influenza A virus appear to be due to laborato

146 nt is not the primary cause of morphological stasis in Malpighiaceae.

147 f angiosperms are still mired in a prolonged stasis in mitochondrial gene content, containing nearly

148 us (MMTV)-v-Ha-ras transgenic mice and tumor stasis in MMTV-N-ras mice.

149 ortant general question is whether long-term stasis in morphological evolution is associated with sta

150 This negative-feedback loop imposes stasis in neuroectoderm and mesendoderm differentiation,

151 d by PRL in mammosphere cultures and by milk stasis in nursing dams, suggesting that the gene is cont

152 istaltic contractions resulted in esophageal stasis in patients with GERD or SERD.

153 In addition, TSA prevented vascular stasis in sickle mice, it exhibited activity as an iron

154 inhibition by tin protoporphyrin exacerbates stasis in sickle mice.

155 -kB activation and H/R-induced microvascular stasis in sickle mice.

156 e (CO) or biliverdin, inhibits microvascular stasis in sickle mice.

157 and adhesion molecules that promote vascular stasis in sickle, but not in normal, mice in response to

158 dhesion molecules and promotes microvascular stasis in sickle, but not normal, mice in response to hy

159 ates indicates a high degree of evolutionary stasis in some CTV populations.

160 At day 1, vascular stasis in the dermis showed a steeper dose-response with

161 Abnormal changes in flow are evident by stasis in the left atrium, and seen as spontaneous echoc

162 evelopment of the upright posture and venous stasis in the lower extremities.

163 t harvestmen implies extensive morphological stasis in the order.

164 Apparent stasis in the size of a sexually selected trait thus mas

165 1 and inhibits hypoxia/reoxygenation-induced stasis in the skin of sickle mice.

166 ambrian Stages 3-5 - revealing morphological stasis in the wake of the Cambrian explosion.

167 extraordinary case of long-term evolutionary stasis in these adaptations.

168 gher than 42 degrees C led to hemorrhage and stasis in tumor vessels.

169 The multipeak landscape imposes evolutionary stasis, in which control systems resist invasion by incr

170 We established a stasis-induced DVT model in murine jugular veins and als

171 In a model of stasis-induced thrombosis created by ligation of the inf

172 imal hyperplasia in an experimental model of stasis-induced vascular remodeling, yet (4) may suppress

173 een for prolactin shows long periods of near-stasis interrupted by occasional bursts of rapid change,

174 that it is punctuated, with long periods of stasis interspersed by sudden gains or losses of multipl

175 As in previous studies, we find that stasis is common in the fossil record, as is a strict ve

176 variation in microsporogenesis, and that the stasis is likely to be due principally to selective pres

177 account for radiation despite morphological stasis is that although selection on pollinator efficien

178 One possible explanation for this stasis is that there are genetic or developmental constr

179 The first barrier, stasis, is mediated by the retinoblastoma protein and ca

180 by cultured HMEC in which the first barrier, stasis, is retinoblastoma-mediated and independent of te

181 Flow stasis leads to acute endothelial dysfunction and apopto

182 n and inhibits hypoxia/reoxygenation-induced stasis, leukocyte-endothelium interactions, and NF-kappa

183 F precipitate an extensive retinal leukocyte stasis (leukostasis) that coincides with enhanced vascul

184 F(120) and VEGF(164), for inducing leukocyte stasis (leukostasis) within the retinal vasculature and

185 Historically attributed to blood stasis, little is known about the adverse effects of ele

186 changes in gastric function such as gastric stasis, loss of appetite, nausea, and vomiting.

187 Despite the apparent stasis, mass was associated with weather across the prev

188 Fossil data suggest that stasis may be a common mode of evolution, while modern d

189 ctive programs, and that this consequence of stasis may be a target for pharmacological modulation.

190 Nevertheless, evolutionary stasis may occur for traits involved in social interacti

191 Using a stasis model of DVT in the mouse, we investigated the ro

192 Using the stasis model of venous thrombosis and resolution in mice

193 Using a mouse stasis model of VT, we found that gal3bp and gal3 were l

194 No phenotype in the complete stasis model was observed.

195 ncreased thrombus formation in a mouse blood stasis model.

196 (n = 2), recurrent UTI (n = 2), and urinary stasis (n = 2).

197 of digestion manifested as gastrointestinal stasis, nausea, and emesis associated with illness.

198 ogical patterns, including the prevalence of stasis, need not be inconsistent with adaptive evolution

199 ional relationship between melanocyte growth stasis, nevus biology, and fibrogenic signaling was furt

200 We test whether the long-term evolutionary stasis observed for pollen morphogenesis (microsporogene

201 l artery of the right kidney until capillary stasis occurred.

202 slowed antegrade flow, before total vascular stasis) occurred in 12 of 154 (7.8%) radioembolization p

203 In the absence of TGR5, intrahepatic stasis of abnormally hydrophobic bile and excessive infl

204 nct gills and a stalk, suggests evolutionary stasis of body form for approximately 99 Myr and highlig

205 The subsequent stasis of ingested food not only leads to symptoms of dy

206 VWAK and FYAK after onset of disease led to stasis of its progression and suppression of histopathol

207 n, may have contributed to the ~700,000 year stasis of the Oldowan technocomplex, and (ii) teaching o

208 ents aged > 55 yrs and those with vallecular stasis on FEES examination were at significantly higher

209 (2) ascertaining if the consequences of cold stasis on the hepatic endothelium can be pharmacological

210 ly reported and are possibly related to milk stasis or apoptosis associated with lactation.

211 g a stable toxin protein that can cause cell stasis or death, another encoding a labile antitoxin pro

212 contrast, venous thrombosis is dominated by stasis or depressed flows, endothelial inflammation, whi

213 ame fixed, followed by periods with relative stasis or random substitutions that did not persist.

214 spheres thus may be more suitable when early stasis or reflux is a concern, in the setting of hepatoc

215 alpha inhibition resulted in transient tumor stasis or tumor regression, and inhibiting HIF-1alpha in

216 otected from thrombosis induced by complete (stasis) or partial (stenosis) flow restriction in the IV

217 s where they reside under conditions of near stasis, or to quickly rise towards the surface and erupt

218 ed, and demonstrates remarkable evolutionary stasis over 425 million years.

219 shoe crabs, noted for relative morphological stasis over geological time, suggests that genomic diver

220 pheromone delivery system show evolutionary stasis over millions of years.

221 individual gene segments, suggesting genetic stasis over recent years.

222 ified each other, producing a net outcome of stasis over time.

223 trols: increased erythrocyte aggregation, at stasis (P < 0.001) and low shear stress (P < 0.001), inc

224 While the causes underlying the stasis paradox are hotly debated, comprehensive attempts

225 This so-called "stasis paradox" highlights our inability to predict evol

226 h mutants, long fin and rapunzel, bypass the stasis phase of the fin ray growth cycle to develop asym

227 Cultured pre-stasis populations contained cells expressing markers as

228 We suggest that hypoxia-induced stasis preserves the status quo of embryonic processes a

229 s is steady, or whether there are periods of stasis punctuated by occasional large changes.

230 ith 4D flow-based LA velocities (r=0.41) and stasis (r=-0.39).

231 cused overwhelmingly on three simple models: stasis, random walks, and directional evolution.

232 ggested that the toxin MazF(Sa) induced cell stasis rather than cell death.

233 allows for assays of agents that induce cell stasis rather than death.

234 ugs which are anticipated to result in tumor stasis rather than regression.

235 ased intraabdominal pressure enhances venous stasis, reduces intraoperative portal venous blood flow,

236 involves inflammation, coagulation, vascular stasis, reperfusion injury, iron-based oxidative biochem

237 ere they contributed to a complex pattern of stasis, replacement, and transformation.

238 Stasis represents the consequences of growth conditions

239 The former hypothesis of morphological stasis requires most living platyrrhine genera to have d

240 ombination machinery, accurate reproduction, stasis, resistance to radical deleterious evolutionary c

241 Congenital IHBDD predisposes to biliary stasis, resulting in intrahepatic lithiasis, septic comp

242 thelial ion transport likely initiates mucus stasis, resulting in persistent airway infections and ch

243 lymphedema specimens, we show that lymphatic stasis results in a CD4 T-cell inflammation and T-helper

244 Initially, milk stasis results in the induction of local factors that ca

245 All eyes had varying degrees of venous stasis retinopathy and intraretinal edema overlying the

246 wild vertebrate populations, and phenotypic stasis seems to be the norm.

247 er gallbladder volumes (predisposing to bile stasis), significant retardation of small-intestinal tra

248 on secondary to gradients of lymphatic fluid stasis stabilizes HIF-1alpha thereafter (3-6 wk).

249 , prolonging survival concomitant with tumor stasis (stable disease).

250 exogenous acute and chronic stress signals (STASIS: stress or aberrant signaling-induced senescence)

251 Urinary stasis, surgical disruption of urogenital tissues, and a

252 ditions for intraspecific dominance, whereas stasis tends to homogenize the system.

253 oblasts showed greater similarity to HMEC at stasis than at telomere dysfunction, although their gene

254 a3 is a local mammary factor induced by milk stasis that causes apoptosis in the mammary gland epithe

255 the fossil record, as is a strict version of stasis that entails no real evolutionary changes.

256 d by remarkable ecological and morphological stasis that persists to the present day.

257 ly reduced GI motility, culminating in frank stasis that was primarily responsible for decreasing lon

258 A 4-m.y. period of climatic and evolutionary stasis then ensued.

259 P4OX) had little to no effect on H/R-induced stasis, though unmodified oxyhemoglobin exacerbated stas

260 3.1 human prostate xenograft model, inducing stasis throughout the approximately 30-day dosing.

261 irectional change, unbiased random walk, and stasis to a dataset of 635 traits across 153 species lin

262 r view of this period from one of biological stasis to a time of continued high activity levels.

263 elements that reduce shear stress and avoid stasis to reduce the frequent adverse events of bleeding

264 cal interactions, whereas both Red-Queen and stasis type of evolution may result if the ecological in

265 f P multocida via his cat licking the venous stasis ulcers on his legs.

266 Venous stasis ulcers resolved in all but three patients.

267 Thirty-seven patients had pretibial venous stasis ulcers, 4 had bronze edema, 23 had both, and 17 h

268 us stasis disease including pretibial venous stasis ulcers, bronze edema, and cellulitis.

269 ea, obesity hypoventilation syndrome, venous stasis ulcers, intestinal leak, small bowel obstruction,

270 ch clots triggered by inflammation and blood stasis, underlie devastating, and sometimes fatal, occlu

271 of 22 faunas spanning the Holocene documents stasis up to the middle Holocene in all traits studied (

272 information on a millennium of sociocultural stasis, variability, change, and adaptation.

273 ify atrial peak velocity, mean velocity, and stasis (velocities <0.1 m/s).

274 ignificantly between HMEC populations at the stasis versus telomere dysfunction senescence barriers.

275 Evaluation of stasis via imaging and biomarkers associated with thromb

276 s grown in a serum-free medium that overcame stasis via silencing of p16 expression and that display

277 tail lymphedema model where sustained fluid stasis was generated on disruption of lymphatic flow, re

278 tently lower (by 21%/12%; P<0.001) while LAA stasis was higher (by 58%; P<0.001) compared with the LA

279 ly, the degree of intracapillary erythrocyte stasis was less in this group than in the infarcted segm

280 f evolutionary processes, we found that this stasis was mostly attributable to a decrease in the fide

281 Vascular stasis was not seen in these experiments.

282 Complete stasis was observed at 40 mg/kg in the BXPC3 human pancr

283 few to hundreds of changes, depending on how stasis was overcome.

284 r to determine whether other factors promote stasis, we compared the fitness trajectories of populati

285 Examining T-cell recruitment in human venous stasis, we show that superficial varicose veins preferen

286 te of mycobacterial ribosomes during hypoxic stasis, we show that the dormancy regulator DosR is requ

287 ntrast, lower LAA velocity and increased LAA stasis were only found in a fraction (38 of 60) of AF pa

288 , mucin hypersecretion likely produces mucus stasis, which contributes to key infectious and inflamma

289 ecretion; reduction of bile flow and biliary stasis, which leads to the development of cholestasis; a

290 model, such analytically derived conditions: Stasis will predominantly emerge whenever the ecological

291 hypoxia or nitric oxide results in bacterial stasis with concomitant induction of a 47-gene regulon c

292 Chronic pouch stasis with diarrhea, frequency, urgency, and soiling gr

293 bition of PABP1 and SMB methylation and cell stasis with IC50 values in the nanomolar range.

294 icroembolization of atherothrombotic debris, stasis with intravascular cell aggregates, and finally,

295 east, a pattern of prolonged periods of near-stasis with occasional episodes of rapid change provides

296 desert-soil microbial communities enter into stasis, with limited species turnover, and reactivate ra

297 re required for preservation of regenerative stasis within diverse epithelial tissues.

298 t forward as an explanation for evolutionary stasis within lineages and niche conservatism within cla

299 relative frequency of gradual change versus stasis within lineages.

300 antioxidant treatment blocked heme-mediated stasis, WPB degranulation, and oxidant production.