ライフサイエンスコーパス: stem cell

1 NPCs are largely preexisting in pluripotent stem cells.

2 disease to be generated-e.g., in pluripotent stem cells.

3 nes in Naa10p-knockout embryos and embryonic stem cells.

4 of Runx1 in the generation of hematopoietic stem cells.

5 induce osteogenesis of human adipose-derived stem cells.

6 monly occurs among aging human hematopoietic stem cells.

7 panding a therapeutically relevant number of stem cells.

8 ntly replenished by differentiation of taste stem cells.

9 select subsets of ribosomes within embryonic stem cells.

10 embryonic stem cells and induced pluripotent stem cells.

11 ormation in frog embryos and human embryonic stem cells.

12 DNA demethylation in somatic and pluripotent stem cells.

13 ol III inhibition specifically in intestinal stem cells.

14 ad alphaKG-sensitive expression in embryonic stem cells.

15 ly maintained by distinct lineage-restricted stem cells.

16 ntiation and bone formation from mesenchymal stem cells.

17 pulation during differentiation of embryonic stem cells.

18 protein normally expressed only in embryonic stem cells.

19 ne-rich stretches attenuate the potential of stem cell active homeobox genes to acquire oncogenic pro

20 elial population and an increase in in vitro stem cell activity.

21 oxygen supply, an environmental regulator of stem cell activity.

22 Shi et al. (2017) in this issue of Cell Stem Cell and Tiyaboonchai et al. (2017) in a recent iss

23 tant ovarian cancer cells and ovarian cancer stem cells and (ii) downregulation of beta-catenin is pa

24 re, we analyzed gene expression in mammalian stem cells and cells at various stages of differentiatio

25 at ablation of PRC2 genes in human embryonic stem cells and in mice results in changes in pluripotenc

26 as indicated by our analyses in human neural stem cells and in the human brain.

27 and by direct conversion of mouse embryonic stem cells and induced pluripotent stem cells.

28 Replicating Lgr5(+) stem cells and quiescent Bmi1(+) cells behave as intesti

29 ment was unable to improve the myogenesis of stem cells and reduce fibrosis in dKO muscle.

30 teasome activity is regulated in HD affected stem cells and somatic cells remains largely unclear.

31 New cells in the meristem are generated by stem cells and transit-amplifying cells, which together

32 e mechanism is not active in mouse embryonic stem cells, and in vitro differentiation promotes only p

33 specific effects of high iron on the brain, stem cells, and the process of erythropoiesis and identi

34 mbination of proteins mucin-5AC and prostate stem-cell antigen could identify high-grade dysplasia/ca

35 Conversely, stem cells are also able to directly modulate the immune

36 Liver-derived stem cells are in clinical development for inborn and ac

37 hed synchronized cultures of mouse embryonic stem cells as they exit the ground state of pluripotency

38 ved in the interaction between hematopoietic stem cells (as well as hematologic and solid tumor cells

39 e milieu for the recruitment of the CXCR2(+) stem cells, as validated by in vitro and in-matrix migra

40 steogenic differentiation of adipose-derived stem cells (ASCs) was significantly enhanced as indicate

41 rticularly under conditions of limited donor stem cell availability.

42 inuously growing mouse incisor as a model of stem cell-based tissue renewal, we found that the transc

43 neity associated with retinal diseases makes stem-cell-based therapies an attractive strategy for per

44 rug resistance is supported by breast cancer stem cells (BCSCs).

45 n emerged as signaling molecules to regulate stem cell behaviors such as migration.

46 enome to facilitate further understanding of stem cell biology and engineering of stem cells for ther

47 unctions of KLFs in mammalian embryogenesis, stem cell biology and regeneration, as revealed by studi

48 uring embryonic development and for applying stem cell biology to regenerative medicine and disease m

49 ng fields such as cancer, developmental, and stem cell biology.

50 a support a model in which a single neuronal stem cell can produce a large number of interneurons wit

51 e report that cultures of expanded potential stem cells can be established from individual eight-cell

52 mation, proliferation and differentiation of stem cell, cell survival/death, and cellular metabolism

53 eneration of more robust induced pluripotent stem cells, characterized by enhanced pluripotency-assoc

54 In this issue of Cell Stem Cell, Chen et al. (2017) delineate an elegant hista

55 re white adipocytes, multipotent mesenchymal stem cells, committed progenitor cells, fibroblasts, end

56 the activation of oncogenic pathways in the stem cell compartment and how wild-type cells limit the

57 pecifically into the primitive hematopoietic stem cell compartment through the utilization of a modif

58 is different from human cornea, where limbal stem cell concept has been well established and accepted

59 Induced pluripotent stem cells could potentially help to elucidate the compl

60 interest from primary CD34(+) hematopoietic stem cells (cRBCs).

61 lial-mesenchymal transition (EMT) and cancer stem cell (CSC) acquisitions.

62 treatment, and possessed the greatest cancer stem cell (CSC) content.

63 cancer tumorigenesis, metastasis, and cancer stem cell (CSC) maintenance.

64 er converts noncancer stem cells into cancer stem cells (CSC) leading to therapy resistance remains p

65 Elimination of self-renewing cancer stem cells (CSCs) is necessary to permanently eradicate

66 rated that DACH1 inversely related to cancer stem cells (CSCs) markers, epithelial-mesenchymal transi

67 ating and metastatic capacity, termed cancer stem cells (CSCs).

68 Improvements in stem cell culture methods, materials and biophysical too

69 Most methods for inducing Wnt signaling in stem cell cultures do not control the spatial presentati

70 phB1-ephrin-B1 pathway is disrupted in human stem cell derived astrocyte and mouse models of amyotrop

71 This enabled us to discover that neural stem cells, derived from the murine spinal cord and orga

72 have emerged as two distinct approaches for stem cell-derived 3D tissue preparation.

73 drug effects with human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) provide new

74 beat amplitude in human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), but D-ala,

75 Stem cell-derived cardiomyocytes mutated to carry the ef

76 Stem cell-derived cardiomyocytes provide a promising too

77 proximately 50 000 human-induced pluripotent stem cell-derived cardiomyocytes, smooth muscle cells, a

78 Human and mouse pluripotent stem cell-derived CMs (PSC-CMs) were transduced with the

79 derived fibroblasts, and induced pluripotent stem cell-derived dopaminergic neurons.

80 n endocrine-active human-induced pluripotent stem cell-derived foregut epithelial cells and hypothala

81 larly discuss the importance of benchmarking stem cell-derived hepatocyte-like cells to their termina

82 kin or SLP-2, as well as induced pluripotent stem cell-derived neurons from Parkin mutation carriers,

83 g the landscape of open chromatin regions in stem cell-derived neurons helps functional interpretatio

84 how that the same pathway is active in human stem cell-derived RGCs.

85 Well-characterized human pluripotent stem-cell-derived ventricular cardiomyocytes are strateg

86 We find that during embryonic stem cell differentiation loss of HMGNs leads to down re

87 ompared with bone marrow-derived mesenchymal stem cells, displayed a 55-fold increase in the expressi

88 tumor cells that inhibits the rate of tumor stem cell division.

89 d/or proliferation of adult intestinal adult stem cells during postembryonic development in vertebrat

90 Therefore, the effect of sulindac on stem cell dynamics was studied.

91 AP patients significantly altered colorectal stem cell dynamics, which might explain the chemoprevent

92 triple antibiotic paste, ferret dental pulp stem cells, encapsulated in a hydrogel scaffold, were in

93 -genome interaction maps for human embryonic stem cells (ESCs) and human embryonic kidney (HEK) cells

94 TET1ALT is repressed in embryonic stem cells (ESCs) but becomes activated in embryonic and

95 t aberrant differences relative to embryonic stem cells (ESCs).

96 paired autophagy, mitochondrial dysfunction, stem cell exhaustion, epigenetic changes, abnormal micro

97 e aim of obtaining a deeper understanding of stem cell fate computation, in order to influence experi

98 the compounds' unique abilities to regulate stem cell fate provides opportunities for developing imp

99 Stem-cell fate can be influenced by metabolite levels in

100 However, the mechanisms that regulate stem cell fates under such widely varying conditions are

101 ding of stem cell biology and engineering of stem cells for therapeutic applications.

102 r emphasis on mechanisms relevant for cancer stem cell formation (CSC) and function.

103 In this issue of Cell Stem Cell, Forrest et al. (2017) demonstrate that studyi

104 test whether a new population of mesenchymal stem cells from human gingiva (GMSCs), which has many ad

105 Repeated cell divisions and aging impair stem cell function.

106 metabolite levels in normal tissues regulate stem-cell function in vivo.

107 With increasing age, stem cell functional abilities decline, resulting in red

108 As p53 is central to hematopoietic stem cell functions, its aberrations affect AML evolutio

109 pathway that regulate cell proliferation and stem cell functions.

110 e understanding of the role of glioma cancer stem cells (GCSCs) in the virulence of gliomas.

111 on pathways, along with the re-activation of stem cell genes, in the degenerating hippocampus.

112 and proved even to efficiently block cancer stem cell growth.

113 glioma cell lines and patient-derived glioma stem cells (GSCs), EGFR signaling promotes H3K23 acetyla

114 of self-renewing, highly tumorigenic glioma stem cells (GSCs), which contributes to tumor initiation

115 le glioblastoma (grade IV glioma) and glioma stem cells (GSCs).

116 The human amniotic fluid stem cell (hAFSC) population consists of two morphologic

117 Stem cell harvest for future use may be considered in fi

118 Neural stem cells have been envisioned as a source of donor cel

119 VIII (FVIII) synthesis site, and mesenchymal stem cells have been shown to control joint bleeding in

120 and transplanted RGC-like cells derived from stem cells have the potential to replace neurons that ha

121 veral human stem cell lines: human embryonic stem cell (hESC) line carrying the common T158M mutation

122 ds (COs) from differentiated human embryonic stem cells (hESCs) or induced pluripotent stem cells (iP

123 Human induced pluripotent stem cells (hiPSCs) are invaluable to study developmenta

124 Genome editing of human induced pluripotent stem cells (hiPSCs) offers unprecedented opportunities f

125 LE: Myocardial delivery of human mesenchymal stem cells (hMSCs) is an emerging therapy for treating t

126 Cartilage grown from human mesenchymal stem cells (hMSCs) is poorly organized and unstable in v

127 f adipose tissue - derived human mesenchymal stem cells (hMSCs) was evaluated in vitro.

128 sfully differentiated from human pluripotent stem cells (hPSCs) and hold the potential to generate an

129 Human pluripotent stem cells (hPSCs) are adhesion-dependent cells that req

130 Cardiomyocyte creation by human pluripotent stem cells (hPSCs) has generated opportunities for heart

131 Human pluripotent stem cells (hPSCs) provide a valuable model for the stud

132 gether promote quiescent human hematopoietic stem cell (HSC) expansion ex vivo have been identified;

133 Hematopoietic stem cells (HSCs) are mobilized from niches in the bone

134 Single hematopoietic stem cells (HSCs) have been functionally shown to genera

135 longed exit from quiescence by hematopoietic stem cells (HSCs) progressively impairs their homeostasi

136 Hematopoietic stem cells (HSCs) reside at the top of the hematopoietic

137 rough the engraftment of human hematopoietic stem cells (HSCs) that can lead to human hematopoiesis w

138 The use of allogeneic hematopoietic stem cells (HSCs) to treat genetic blood cell diseases h

139 Upon aging, hematopoietic stem cells (HSCs) undergo changes in function and struct

140 hens the protective effect of amniotic fluid stem cells in a renal ischemia-reperfusion injury model.

141 To determine the role of HF keratinocyte stem cells in beta-HPV-induced skin carcinogenesis, we u

142 e therapeutic effect of human amniotic fluid stem cells in rats with renal ischemia-reperfusion injur

143 ony or cluster-forming capacity of human CML stem cells in the absence or presence of IM, respectivel

144 ine and biointerfacing activities of natural stem cells in therapeutic cardiac regeneration.

145 Chemotherapy has been shown to enrich cancer stem cells in tumors.

146 ids have been derived from human pluripotent stem cells in vitro, but generating a human ovarian foll

147 a GFP reporter gene into adult hematopoietic stem cells in vivo, which are predominantly quiescent, b

148 Upon injury, stem cells increase proliferation, followed by lineage d

149 standard care and p=0.75 for the G-CSF plus stem-cell infusion group vs standard care).

150 e-mediated miRNA transfer converts noncancer stem cells into cancer stem cells (CSC) leading to thera

151 irected differentiation of human pluripotent stem cells into haemogenic endothelium followed by scree

152 ) signaling and therefore differentiation of stem cells into megakaryocytes.

153 direct differentiation of human pluripotent stem cells into organoids - aggregates with multiple tis

154 icated in the differentiation of mesenchymal stem cells into various cell lineages.

155 ant RTT patient-specific induced pluripotent stem cell (iPSC) line carrying the V247fs mutation (V247

156 derived a collection of induced pluripotent stem cell (iPSC) lines capturing a range of disease stag

157 d-type (WT) and three HD induced-pluripotent stem cell (iPSC) lines.

158 ears, rapid emergence of induced pluripotent stem cells (iPSC) and iPSC-derived cardiomyocytes presen

159 cells] from primed-state induced pluripotent stem cells (iPSCs) after a 72-hour transient incubation

160 their tissue to generate induced pluripotent stem cells (iPSCs) and hepatocyte-like cells (HLCs) for

161 Human induced pluripotent stem cells (iPSCs) are ideal cell sources for personaliz

162 uman retinoblastomas and induced pluripotent stem cells (iPSCs) derived from murine rod photoreceptor

163 ming of somatic cells to induced pluripotent stem cells (iPSCs) holds enormous promise for regenerati

164 Induced pluripotent stem cells (iPSCs) show variable methylation patterns be

165 rough differentiation of induced pluripotent stem cells (iPSCs) to study cellular pathophysiology.

166 ic stem cells (hESCs) or induced pluripotent stem cells (iPSCs).

167 in which eye tissue production by planarian stem cells is not directly regulated by the absence of t

168 on and quiescence of myogenic progenitor and stem cells is tightly regulated to ensure appropriate sk

169 in somatic cells, but its role in embryonic stem cells is unknown.

170 Activity of satellite cells, skeletal muscle stem cells, is altered following a burn injury and likel

171 elopment, especially in organ-specific adult stem cells, is unclear.

172 quiescent Bmi1(+) cells behave as intestinal stem cells (ISCs) in vivo.

173 In this issue of Cell Stem Cell, Kee et al. (2017) and Kirkeby et al. (2017) i

174 etion of these shadow enhancers in embryonic stem cells leads to impaired activation of HoxA genes up

175 pression of EVI1 and SOX9 is associated with stem cell-like and metastasis signatures, and their depl

176 Importantly, AZD4547 impaired stem cell-like characteristics in primary MECs and spont

177 uffered cytotoxic stress and thereby enter a stem cell-like state, the seeds for recurrence.

178 ate potentials and branchpoints in olfactory stem cell lineage trajectories.

179 derived from a single dominant hematopoietic stem cell lineage.

180 ibit merged chromatin profiles from distinct stem cell lineages.

181 iple human embryonic and induced pluripotent stem cell lines and have potential applications for both

182 in human cells, we established several human stem cell lines: human embryonic stem cell (hESC) line c

183 in realizing the goal of targeting leukemic stem cells (LSCs).

184 monstrate that Prdm16 is required for neural stem cell maintenance and neurogenesis in the adult late

185 nized role in mammary ductal development and stem cell maintenance, but the ligands involved are ill-

186 role of beta-catenin and SNAIL in epidermal stem cell maintenance.

187 e formation and for the expression of neural stem cell markers and Notch target genes in primary neur

188 teosarcoma cells decreases the expression of stem cell markers and suppresses sarcosphere formation,

189 expression of the master EMT regulators and stem cell markers.

190 this activates tissue-specific expression of stem cell markers.

191 of specific microRNAs in controlling mammary stem cell (MaSC) activity and breast cancer formation re

192 hibit an expansion of the mammary epithelial stem cell (MaSC) enriched basal/myoepithelial population

193 ize the extent to which TNBC versus non-TNBC stem cells may differ.

194 differentiation at which they are harvested, stem cells may exhibit different properties.

195 e effective, but reduced numbers of residual stem cells may limit their efficacy.

196 d with chimeric-competent human pluriopotent stem cells may serve as a suitable platform for the xeno

197 polarized, asymmetric divisions of stomatal stem cells (meristemoid mother cells [MMCs]) are fundame

198 uggest that programmed differences in infant stem cell metabolism correspond with differences in body

199 The role of metabolites produced from stem cell metabolism has been emerged as signaling molec

200 , using murine and human induced pluripotent stem cell models, that RPGR interacts with and activates

201 FOXO1 activates a stem cell molecular signature that is also present in AE

202 xample, CDC42, CDC42EP3, RAC1 and ARPC5) and stem cell molecules CD44 and EZH2, all of which are vali

203 RATIONALE: Virtually all mesenchymal stem cell (MSC) studies assume that therapeutic effects

204 vestigated the potential role of mesenchymal stem cells (MSCs) derived from human MT in the pathogene

205 and efficacy of allogeneic human mesenchymal stem cells (MSCs) in reducing the time to recovery from

206 ulticolor lineage tracing of skeletal muscle stem cells (MuSCs) to address these questions.

207 generated by asymmetrically dividing neural stem cells (neuroblasts).

208 ystem plays a central role in regulating the stem cell niche in many organs, and thereby pivotally mo

209 hat influenced their ability to colonize the stem cell niche.

210 uniquely affects the formation of the larval stem cell niches, without altering other midgut cell typ

211 Neural stem cells (NSCs) are a heterogeneous population of cell

212 the normal cycling and maintenance of neural stem cells (NSCs) in the brain subependymal zone of adul

213 Pum2, severely reduced the number of neural stem cells (NSCs) in the postnatal dentate gyrus (DG), d

214 in inflammation/gliosis and increased neural stem cell numbers in areas of tissue injury.

215 y (including embryology) is proposed as "the stem cell of biological disciplines." Genetics, cell bio

216 Typically, stem cells of independent lineages work coordinately wit

217 ceptor-5 (LGR5) is expressed in adult tissue stem cells of many epithelia, and its overexpression is

218 This review focuses on the epithelial stem cells of skin, where they come from, where they res

219 Periodontal ligament mesenchymal stem cells (PDLMSCs) are responsible for regeneration of

220 e integrity, but also closely correlate with stem cell pluripotency, cancer drug resistance, GSL stor

221 ulators of signalling pathways that regulate stem-cell pluripotency, including the TGFbeta superfamil

222 morsphere formation and ALDH-positive cancer stem cell population, in vitro.

223 r controlling the make-up of the pluripotent stem cell population.

224 entiated cells, consistent with a progenitor/stem cell population.

225 ukemic ETV6-RUNX1 expression in hematopoetic stem cells/precursor cells (HSC/PC) and postnatal infect

226 sly to facilitate cell-cycle progression and stem cell proliferation.

227 o the presence of epithelial and mesenchymal stem cells-provides a model for the study of ectodermal

228 specific enrichment of xenogenic pluripotent stem cell (PSC) derivatives.

229 ifferentiated NKX2-1GFP reporter pluripotent stem cells (PSCs) in vitro to generate and isolate human

230 known cultured stem cell types, pluripotent stem cells (PSCs) sit atop the landscape of developmenta

231 The identification of a stem cell regulatory gene which is aberrantly expressed

232 chemotherapy-induced senescence could change stem-cell-related properties of malignant cells.

233 A-binding proteins (RBPs) that govern cancer stem cells remains poorly characterized.

234 ision is the best characterized mechanism of stem cell replacement, but other mechanisms could also b

235 ts of blastomeres, the most primitive cancer stem cells reported to date.

236 Breast cancer stem cells represent the tumor subpopulation involved in

237 Understanding the stem cell response to immune therapies in ongoing human

238 viously showed that MCPH1 deletion in neural stem cells results in early mitotic entry that distracts

239 s provide a biophysical understanding of how stem cell scaling is maintained during organ growth and

240 LC-MS/MS analysis of stem cell secretome revealed the presence of different p

241 evelopment of exogenous molecules to control stem cell self-renewal or differentiation has arrived at

242 Stem cells self-renew and produce progenitors with limit

243 RNAs include Wnt/beta-catenin, TGF-beta, and stem cell signaling.

244 by screening of 26 candidate haematopoietic stem-cell-specifying transcription factors for their cap

245 Thus, Blimp1 expression defines a mammary stem cell subpopulation with unique functional character

246 Development of stem cell technologies for cell replacement therapy has

247 the functional decline and transformation of stem cells that characterize aging.

248 dimensional spheroids from human pluripotent stem cells that resemble either the dorsal or ventral fo

249 y OSNs die, indicating that HBCs are reserve stem cells that respond to severe epithelial injury.

250 The disease is a potential target for stem cell therapy but success is likely to be limited by

251 Application of miR-146b combined with stem cell therapy could enhance regeneration of cartilag

252 RATIONALE: Autologous stem cell therapy using human c-Kit(+) cardiac progenito

253 used fibroblast-derived induced pluripotent stem cells to generate retinal pigment epithelium (RPE)

254 attempts to differentiate human pluripotent stem cells to lung epithelium rely on passing through pr

255 paB-mediated signaling that activates neural stem cells to reconstitute the olfactory epithelium.

256 al cord blood (UCB) is a promising source of stem cells to use in early haematopoietic stem cell tran

257 ating oligodendrocyte properties and discuss stem cell tools to identify microenvironmental factors o

258 ized IONPs are promising contrast agents for stem cell tracking by T2-weighted MRI as they are biocom

259 Sal-like protein 4 (SALL4), an embryonic stem cell transcriptional regulator, is re-expressed by

260 e (p < 0.0001) and not undergoing allogeneic stem cell transplant (SCT, p = 0.0005) predicted poor ov

261 -melphalan with low-dose TBI after haplocord stem cell transplant assures good engraftment and leads

262 yeloablative chemotherapy with hematopoietic stem-cell transplant followed by adjuvant retinoid diffe

263 eauville score </=2) proceeded to autologous stem cell transplantation (ASCT) whereas PET-positive pa

264 on, and patients could proceed to autologous stem cell transplantation (ASCT).

265 of stem cells to use in early haematopoietic stem cell transplantation (HSCT) approaches for several

266 ing complication of allogeneic hematopoietic stem cell transplantation (HSCT), posing as a significan

267 tment failure after allogeneic hematopoietic stem cell transplantation (HSCT).

268 ion is a major complication after allogeneic stem cell transplantation (SCT).

269 ditional studies and referral for allogeneic stem cell transplantation are also discussed.

270 lleagues asked whether the results of neural stem cell transplantation might be improved by accommoda

271 rophy treated with allogeneic haematopoietic stem cell transplantation on a compassionate basis in fo

272 The success of allogeneic hematopoietic stem cell transplantation, a key treatment for many diso

273 -SIGN (rs11465384 and rs7248637), allogeneic stem cell transplantation, respiratory virus infection,

274 who are potential candidates for autologous stem cell transplantation.

275 ed into intensive strategies with autologous stem cell transplantation.

276 be achievable with allogeneic hematopoietic stem cell transplantation.

277 27-321) days after allogeneic hematopoietic stem cell transplantation.

278 atently infected cells before haematopoietic stem cell transplantation.

279 curative option for CMML remains allogeneic stem cell transplantation.

280 lenalidomide versus placebo after autologous stem-cell transplantation (ASCT) was investigated for pa

281 GVHD who had received consecutive allogeneic stem-cell transplantation.

282 iduals, particularly those who have received stem cell transplants.

283 Stem cell treatments for neurodegenerative diseases are

284 evidence unveiled the existence of different stem cell types in various tissues with efficient capabi

285 Of all known cultured stem cell types, pluripotent stem cells (PSCs) sit atop

286 been implicated in the biology of different stem cell types, yet they have not been studied in HFSCs

287 Using umbilical cord-derived mesenchymal stem cells (uMSC) from offspring born to normal-weight a

288 ing tumor cell motility and invasion, cancer stem cell viability and differentiation, resistance to a

289 re, to yield functional human haematopoietic stem cells, we perform morphogen-directed differentiatio

290 ory networks in both neural and glioblastoma stem cells, we subjected both cell types to in-vitro dif

291 48 hours later, immune-matched or mismatched stem cells were implanted into osteochondral defects of

292 Mouse AML and BC-CML stem cells were MHCI+ without IFN-gamma stimulation, sug

293 Human periodontal ligament stem cells were seeded on an OPN-coated surface.

294 In conclusion, CMMPs act as 'synthetic stem cells' which mimic the paracrine and biointerfacing

295 ults from somatic mutations in hematopoietic stem cells, which give an advantage to mutant cells, dri

296 Muscle satellite cells are myogenic stem cells whose quiescence, activation, self-renewal, a

297 d autosome loss in aneuploid mouse embryonic stem cells with an extra human chromosome and human indu

298 Targeting postulated CD19(+) myeloma stem cells with anti-CD19 CAR-Ts is a novel approach to

299 Moreover, human embryonic stem cells with deletion of EZH1 or EZH2 fail to differe

300 man chromosome and human induced pluripotent stem cells with trisomy 21, as well as cancer cells.