ライフサイエンスコーパス: stem cell biology

1 ideal model for this understudied aspect of stem cell biology.

2 attempt to understand how Notch functions in stem cell biology.

3 , together with RNAi, revealed gene roles in stem cell biology.

4 ing has provided unprecedented insights into stem cell biology.

5 has been greatly aided by recent advances in stem cell biology.

6 s but has not been studied in the context of stem cell biology.

7 y desirable in biomedical research including stem cell biology.

8 has seen remarkable advances in the field of stem cell biology.

9 reatment, are poised to benefit greatly from stem cell biology.

10 ls (GSCs) have served as a paradigm in niche-stem cell biology.

11 excellent system for in vivo study of adult stem cell biology.

12 a poorly understood but important problem in stem cell biology.

13 ency are rather poorly understood aspects of stem cell biology.

14 similarly controls normal mammary epithelial stem cell biology.

15 and implicates its potential significance in stem cell biology.

16 own for their role in cancer development and stem cell biology.

17 ty is a fundamental issue in both cancer and stem cell biology.

18 ting a combination of tissue engineering and stem cell biology.

19 form resource for studying hematopoiesis and stem cell biology.

20 idated by considering cancer as a problem in stem cell biology.

21 rface marker, and peculiarly in the field of stem cell biology.

22 differentiation are two central questions in stem cell biology.

23 has been one of the most productive areas of stem cell biology.

24 posed ancestral functions of PUF proteins in stem cell biology.

25 epigenetic research on our understanding of stem cell biology.

26 ns between PLZF and Rb could be important in stem cell biology.

27 ding the role of mitochondrial metabolism in stem cell biology.

28 ovide much needed insight into understanding stem cell biology.

29 ew light on the role of PML in senescence or stem cell biology.

30 fundamental challenges in developmental and stem cell biology.

31 he important role of membrane trafficking in stem cell biology.

32 tudy of regeneration, tissue homeostasis and stem cell biology.

33 ng fields such as cancer, developmental, and stem cell biology.

34 can function as epigenetic reprogrammers in stem cell biology.

35 ertaining to emerging topics of interest for stem cell biology.

36 adult heart disease and the growing field of stem cell biology.

37 nd the understanding of crucial questions of stem cell biology.

38 division and their broader implications for stem cell biology.

39 inent role in controlling several aspects of stem cell biology.

40 ip systems based on cardiac cell culture and stem cell biology.

41 study intrinsic mechanisms of hematopoietic stem cell biology.

42 these interactions is key for understanding stem cell biology.

43 ll self-renewal is a fundamental question in stem cell biology.

44 s in neutrophil maturation and hematopoietic stem cell biology.

45 e adult stem cell niches and their impact on stem cell biology.

46 out the role of this unusual carbohydrate in stem cell biology.

47 newal is fundamental to the understanding of stem cell biology.

48 ndation for a more detailed understanding of stem cell biology.

49 reimplantation development to instruct human stem cell biology.

50 f neural stem cells is a central question in stem cell biology.

51 stems for the in vivo study of hematopoietic stem cell biology.

52 research concerning Heart-on-a-chip based on stem cell biology.

53 as control of organ size, regeneration, and stem cell biology.

54 ata into knowledge of both developmental and stem cell biology.

55 biology, pharmacology, cancer diagnosis and stem cell biology.

56 egulator, with potential roles in cancer and stem cell biology.

57 function in fields such as developmental and stem cell biology.

58 an important role in tissue homeostasis and stem cell biology.

59 lization for gene-repression applications in stem cell biology.

60 trol of pluripotency is of great interest in stem cell biology.

61 d to DDT were used to evaluate the impact on stem cell biology.

62 modifications that regulate skeletal muscle stem cell biology.

63 sed in research in developmental, cancer and stem cell biology.

64 tein that goes beyond its well-known role in stem cell biology.

65 acteristics remain a fundamental question in stem cell biology.

66 i3bp) as a protein important for mesenchymal stem cell biology.

67 s is an important issue in developmental and stem cell biology.

68 l uptake into cells, and also play a role in stem cell biology.

69 e expression regulation in developmental and stem cell biology.

70 nstrate the application of these browsers to stem cell biology.

71 umorigenesis, response to therapy and cancer stem cell biology.

72 to a better understanding of human prostate stem cell biology.

73 ates, functioning in embryogenesis and adult stem cell biology.

74 or miRNA is emerging as an important tool in stem cell biology.

75 n experiments was accounted for by facets of stem cell biology.

76 netic regulation have important functions in stem cell biology, although the interactions between the

77 onicle of concepts in the field of epidermal stem cell biology and a historic look at their developme

78 ic cells is a valuable method for studies of stem cell biology and a promising method for human blood

79 Up to present, SPR application in stem cell biology and biomedical sciences was underused.

80 antigen Sca-1 is implicated in murine cancer stem cell biology and breast cancer models, but the role

81 logy, driven both by the intense activity in stem cell biology and by the emergence of systems biolog

82 hmC and TET proteins have been implicated in stem cell biology and cancer, but information on the gen

83 rowth promoting programs relevant to mammary stem cell biology and cancer.

84 with such probes will facilitate studies of stem cell biology and cell and gene therapy, as well as

85 Research in stem cell biology and cell reprogramming is rapidly adva

86 lays a crucial role in embryonic and somatic stem cell biology and cell reprogramming.

87 We also discuss how progress in stem cell biology and cellular reprogramming has enabled

88 particularly in the fields of neuroscience, stem cell biology and developmental biology.

89 Recent advances in stem cell biology and direct reprogramming, or transdiff

90 l signaling pathways involved in brain tumor stem cell biology and discuss how targeting these molecu

91 lored the role of TSC1 in various aspects of stem cell biology and dissected the extent to which TSC1

92 Advances in stem cell biology and engineering allow for the generati

93 enome to facilitate further understanding of stem cell biology and engineering of stem cells for ther

94 , and meta-regression to study the impact of stem cell biology and experimental design on motor and s

95 These data have implications for stem cell biology and for the analysis of the oncogenici

96 is pathway could be of importance for neural stem cell biology and for understanding the pathogenesis

97 ique potential to address diverse aspects of stem cell biology and gametogenesis.

98 important implications for gastrointestinal stem cell biology and H pylori-induced gastric pathology

99 u represents a major step forward in gastric stem cell biology and has potential implications for gas

100 rrent understanding of how Cripto-1 controls stem cell biology and how it integrates with other major

101 out how H. pylori may adapt to and influence stem cell biology and how its intracellular residency co

102 that propose a role for calcium signaling in stem cell biology and human developmental disorders.

103 Here we highlight the importance of mice in stem cell biology and in bringing the world one step clo

104 cription factor having a central function in stem cell biology and in human cancers.

105 play important roles in normal hematopoietic stem cell biology and in the development of both acute a

106 technology has greatly advanced the field of stem cell biology and nurtured our hope to create patien

107 ving subjects is essential for understanding stem cell biology and physiology.

108 ssion, Wnt signaling in development, cancer, stem cell biology and regeneration, and therapeutics tha

109 unctions of KLFs in mammalian embryogenesis, stem cell biology and regeneration, as revealed by studi

110 rtant model for studies of axial patterning, stem cell biology and regeneration.

111 air follicles are a widely studied model for stem cell biology and regeneration.

112 Research discoveries in the fields of stem cell biology and regenerative medicine are beginnin

113 Rapid advances in stem cell biology and regenerative medicine have opened

114 em cells (iPSCs) are poised to revolutionize stem cell biology and regenerative medicine research, br

115 pluripotent state of ESCs is a key issue in stem cell biology and regenerative medicine, and consequ

116 aise previously undescribed implications for stem cell biology and regenerative medicine.

117 lopment remains a fundamental goal impacting stem cell biology and regenerative medicine.

118 various studies, especially in the fields of stem cell biology and regenerative medicine.

119 poised to have substantial implications for stem cell biology and regenerative medicine.

120 re studies that enhance our understanding of stem cell biology and repair mechanisms will provide a p

121 Today, advances in the fields of stem cell biology and signal transduction are being inte

122 substantial advances in our understanding of stem cell biology and some recent important advances in

123 provide new insights with regard to leukemic stem cell biology and suggest possibilities for the deve

124 Profound advances in human stem cell biology and technology, tissue engineering and

125 ur current understanding of small intestinal stem cell biology and the current tools available for st

126 ve intriguing implications for understanding stem cell biology and the evolution of pathogen resistan

127 o unveil adipose developmental cues, adipose stem cell biology and the regulators of adipose tissue h

128 for both niche plasticity in other areas of stem cell biology and the therapeutic use of neural stem

129 ate, and may ultimately be useful to in vivo stem cell biology and therapy.

130 em cell activity is central to understanding stem cell biology and to developing strategies for the t

131 ning stem cells is critical to understanding stem cell biology and to using stem cells in future rege

132 oscience, hematology, developmental biology, stem cell biology and transgenesis are rapidly emerging.

133 Basic stem cell biology and transplant biology aim to uncover

134 clinical implications in the field of human stem cell biology and transplantation.

135 Despite the wealth of research on stem-cell biology and therapy, there have been few advan

136 rocesses including cellular differentiation, stem cell biology, and cancer development.

137 clearly influence tumorigenesis, pluripotent stem cell biology, and epidermal cell lineage decisions,

138 eshaped our approach to biomedical research, stem cell biology, and human genetics.

139 erizing the effect of this oncogene on human stem cell biology, and in defining its contribution to t

140 as been eclipsed by the rise of genomics and stem cell biology, and in part because it has seemed les

141 ations has dramatically altered the field of stem cell biology, and it has been a major focus of rese

142 ecules will likely provide new insights into stem cell biology, and may ultimately contribute to effe

143 may be important for embryonic development, stem cell biology, and tumor growth.

144 A variety of applications in cancer biology, stem cell biology, apoptosis studies, and high throughpu

145 s contributions to epigenetic regulation and stem cell biology are less explored.

146 NA processing machinery in the regulation of stem cell biology are not well understood.

147 Current models of stem cell biology assume that normal and neoplastic stem

148 retina as an ideal model for studying adult stem cell biology at single cell resolution.

149 HSCs represent a paradigm for the study of stem-cell biology, because robust methods for prospectiv

150 done in the areas of vector development and stem cell biology before the full therapeutic potential

151 hnological advances in micro/nanotechnology, stem cell biology, biomaterials and tissue decellulariza

152 A central unanswered question in stem cell biology, both in plants and in animals, is how

153 profound understanding of the principles of stem cell biology, but also of its potential pitfalls.

154 revealed a fusion of infection biology with stem cell biology by demonstrating developmental reprogr

155 Epigenetic mechanisms play critical roles in stem cell biology by maintaining pluripotency of stem ce

156 ps, smart algorithms), alongside advances in stem cell biology, cell encapsulation methodologies, and

157 The recent confluence of advances in stem cell biology, cell signaling, genome and computatio

158 unctional evidence linking Sox proteins with stem cell biology, cellular reprogramming, and disease w

159 tinued progress in understanding basic human stem cell biology, combined with a better handle on the

160 s to understand how iron exposure influences stem cell biology could be enhanced by establishing plat

161 ntal cues involved in retinal generation and stem cell biology, coupled with extensive surgical resea

162 le to mapped gene expression measurements in stem cell biology, developmental biology, cancer biology

163 iples that have significant implications for stem cell biology, developmental neurobiology, neural pl

164 erve as valuable reagents for studying colon stem cell biology, differentiation, and pathogenesis.

165 have been made in the field of hematopoietic stem cell biology during the past year.

166 KLFs have diverse functions in stem cell biology, embryo patterning, and tissue homoeos

167 Given the rapidly advancing field of stem cell biology, EMBs were subsequently seeded with th

168 ey insights into mammalian developmental and stem cell biology, emphasizing the analytical approaches

169 demethylase LSD1 plays an important role in stem cell biology, especially in the maintenance of the

170 udy of regeneration, tissue homeostasis, and stem cell biology for over a century, but they have not

171 stem cells cautions against inferring adult stem-cell biology from embryonic studies, and has direct

172 Stem Cell Symposium to discuss 'Quantitative stem cell biology: from molecules to models'.

173 In February 2010, researchers interested in stem cell biology gathered in Keystone, Colorado, USA to

174 a critical perspective on recent advances in stem cell biology, gene therapy, cell cycle regulation a

175 forts in nonmammalian and human development, stem cell biology, genetics, materials science, bioengin

176 For motor outcome, facets of stem cell biology had little detectable effect.

177 Stem cell biology has come of age.

178 years, a new subdiscipline of computational stem cell biology has emerged that synthesizes the model

179 Stem cell biology has experienced explosive growth over

180 s (EPCs) in tandem with emerging concepts in stem cell biology has generated enormous interest and ex

181 In this Perspective, we consider how cardiac stem cell biology has led us into clinical trials, and w

182 Understanding epithelial stem cell biology has major clinical implications for th

183 The role of ROS in stem cell biology has not been fully illustrated and und

184 Stem cell biology has the potential to yield new therapi

185 The field of stem-cell biology has been catapulted forward by the sta

186 Human genetics and stem cell biology have advanced neurobiology for neurode

187 ibility and fundamental aspects of embryonic stem cell biology have been localized in a genetic conte

188 ucted in the areas of histocompatibility and stem cell biology have expanded the potential cellular s

189 Recent developments in stem cell biology have generated much excitement for bet

190 rs ago, it is only recently that advances in stem cell biology have given new impetus to the "cancer

191 iew how recent advances in developmental and stem cell biology have made it possible to generate comp

192 Recent advancements in the field of stem cell biology have provided a source of human-based

193 Recent advances in epithelial stem cell biology have resulted in the isolation of hair

194 Recent developments in our understanding of stem-cell biology have profoundly influenced the practic

195 ospective studies of leukemia initiation and stem cell biology in a genetic subtype of poor prognosis

196 p53, homologs of which have no known role in stem cell biology in any invertebrate examined thus far.

197 to be practically useful in studying neural stem cell biology in health and disease.

198 nessing substantial strides in understanding stem cell biology in humans; however, major disappointme

199 anisms that regulate tissue regeneration and stem cell biology in these organisms.

200 ion of neuronal lineages and, more recently, stem cell biology in vertebrates.

201 eld at the intersection of developmental and stem cell biology in which a somatic cell is stably repr

202 a transcription factor widely implicated in stem cell biology, in CNS myelination and remyelination.

203 ficant impact in studying various aspects of stem cell biology including the phenomenon of stem cell

204 ights of general relevance to other areas of stem cell biology including the role of cellular interac

205 cal approaches and engineering principles in stem cell biology, including culture systems, preclinica

206 A better understanding of stem cell biology, including embryonic and adult stem ce

207 These deficits affect multiple aspects of stem cell biology, including quiescence, renewal, and di

208 plications for the role of Myc in cancer and stem cell biology, including that of induced pluripotent

209 ress we have made in understanding epidermal stem cell biology is discussed in this article.

210 An important question in stem cell biology is how a cell decides to self-renew or

211 Therefore, a critical question in stem cell biology is how stem cells escape cell division

212 A fundamental yet unexplored question in stem cell biology is how the fate of tissue stem cells i

213 tors, including microRNAs, whose key role in stem cell biology is just emerging.

214 Information about sertuins in stem cell biology is scarce.

215 Stem cell biology is scientifically, clinically, and pol

216 The central tenet of stem cell biology is that within tissues there reside st

217 A key issue in stem cell biology is the differentiation of homogeneous

218 A major goal in stem cell biology is to gain a sufficient understanding

219 A central issue in stem cell biology is to understand the mechanisms that r

220 A fundamental issue in stem cell biology is whether adult somatic stem cells ar

221 A central question in stem cell biology is whether organ homeostasis is mainta

222 ental yet essentially unexplored question in stem cell biology is whether the stem cell cycle has spe

223 w we discuss some general concepts regarding stem cell biology learned from the study of HSCs with a

224 A major challenge in neuronal stem cell biology lies in characterization of lineage-sp

225 e efficacy of a novel method by which neural stem cell biology may be harnessed for genetically manip

226 tissue engineering and our understanding of stem cell biology may provide a lifelong solution to the

227 The expanding research field of cancer stem-cell biology may offer a novel clinical apparatus t

228 stem (iPS) cells have brought the science of stem cell biology much closer to clinical application fo

229 essential roles in controlling hematopoietic stem cell biology, myeloid and lymphoid differentiation

230 Areas as diverse as stem cell biology, neurobiology, metabolism, and immunit

231 helial morphogenesis, cytoskeletal dynamics, stem cell biology, neurobiology, physiology, etc.

232 otential importance of AC133 to the field of stem cell biology, nothing is known about the transcript

233 Recent advances in genetics and stem cell biology offer new prospects for cell-based mod

234 olecular immunology, tissue engineering, and stem cell biology offer the promise of even better thera

235 Stem cell biology offers advantages to investigators see

236 Little is known about stem cell biology or the specialized environments or nic

237 This review summarizes recent advances in stem cell biology, outlines ongoing clinical trials and

238 siderable advances in the field of embryonic stem cell biology, particularly in the area of pluripote

239 decade with respect to our understanding of stem cell biology, progress has been limited in the deve

240 g in evolutionary and developmental biology, stem cell biology, regeneration and disease.

241 an emerging model species in fields such as stem cell biology, regeneration and evolutionary biology

242 inthes are excellent models for the study of stem cell biology, regeneration and the regulation of sc

243 luence cell behavior, and have importance to stem cell biology, regeneration and transplantation, and

244 s a unifying theme in embryonic development, stem cell biology, regeneration, and cell competition.

245 ll function has significant implications for stem cell biology, repair of lung injuries, and diseases

246 ein arginine methyltransferase with roles in stem cell biology, reprograming, cancer and neurogenesis

247 ng discoveries made recently in the field of stem cell biology, researchers now have improved tools t

248 ypes and that hierarchical models of mammary stem cell biology should encompass bidirectional interco

249 k in limb regeneration, fetal wound healing, stem cell biology, somatic nuclear transfer, and tissue

250 Important issues in stem cell biology, such as stem cell niche, homing, and

251 he major advances in fundamental and applied stem cell biology that emerged.

252 In particular, research in stem cell biology, the cardiomyocyte lineage, and the in

253 In stem cell biology, the dynamic addition and removal of 5

254 e studied AS in a powerful in vivo model for stem cell biology, the planarian Schmidtea mediterranea.

255 h the behavior expected for a tumor based on stem cell biology; this finding has diagnostic and thera

256 plications to drug delivery, drug discovery, stem cell biology, tissue engineering and regenerative m

257 naling pathway that plays important roles in stem cell biology, tissue homeostasis, and cancer develo

258 rugs and the application of gene therapy and stem cell biology to address the genetic abnormalities.

259 slate recent advances in induced pluripotent stem cell biology to clinical regenerative medicine ther

260 ion of molecularly designed biomaterials and stem cell biology to develop stable tissue regeneration.

261 g approaches and the emergent application of stem cell biology to overcome spinal cord injury.

262 For the field of pluripotent stem cell biology to realize its promising future, curre

263 uring embryonic development and for applying stem cell biology to regenerative medicine and disease m

264 of viable intact cells required to translate stem cell biology to regenerative medicine in a simple l

265 helium as well as factors involved in breast stem cell biology tumor initiation and progression.

266 The study of epithelial stem cell biology was aided by the ability to visualize

267 lved, will soon provide a further impetus to stem cell biology with far reaching applications.

268 To connect the transcriptome and stem cell biology, with potential clinical applications,

269 t and function, CNS immune surveillance, and stem cell biology, yet we know surprisingly little about