ライフサイエンスコーパス: stem cell factor

1 YAP1 gene encodes a potent new oncogene and stem cell factor.

2 w stromal cells with IL-15, IL-7, Flt3L, and stem cell factor.

3 ulin-like growth factor-I and membrane-bound stem cell factor.

4 eptor tyrosine kinase, KIT, the receptor for stem cell factor.

5 r mast cells were exposed to the Kit ligand, stem cell factor.

6 ated with mutations in KIT, the receptor for stem cell factor.

7 te-macrophage colony-stimulating factor plus stem cell factor.

8 al stromal cells supplemented with IL-15 and stem cell factor.

9 tro in response to IL-7, erythropoietin, and stem cell factor.

10 rously than EL cells in response to IL-3 and stem cell factor.

11 t auto-phosphorylation induced by the ligand stem cell factor.

12 had relatively higher levels of M-CSF and of stem cell factor.

13 cell line supplemented with human G-CSF and stem cell factor.

14 to granulocyte colony-stimulating factor and stem cell factor.

15 on-Th2 cell-derived mast cell growth factor, stem cell factor.

16 BMC) after priming with fibroblast membranal stem cell factor.

17 epithelial differentiation and inhibitors of stem cell factors.

18 ember, APLP2, showed no correlation to these stem cell factors.

19 Stem cell factor (10 ng/mL) alone was unable to induce m

20 stored Foxn1 expression along with ccl25 and stem cell factor A number of putative targets of miR-205

21 In contrast, the cytokine stem cell factor, a regulator of mast cell differentiati

22 educed colony-forming activity and increased stem-cell-factor activation of the phosphoinositide-3-ki

23 ensions in the presence of interleukin-3 and stem cell factor allowed expansion and maturation of mas

24 Treatment with stem cell factor/AMD3100 led to a greater increase in ci

25 x N1 (Foxn1), and its two regulated targets, stem cell factor and ccl25, following stress.

26 th and retention factors, most significantly stem cell factor and CXCL12, which act preferentially to

27 ective Erk and Akt activation in response to stem cell factor and diminished thrombopoietin-evoked Er

28 In combination with stem cell factor and endothelin 3, LIF induced formation

29 -15Ralpha(-/-) mice were cultured with IL-7, stem cell factor and flt3 ligand, followed by IL-15, the

30 dgehog, bone morphogenetic protein 4 (BMP4), stem cell factor and hypoxia.

31 ing their immortalization in the presence of stem cell factor and IL-3.

32 Stem cell factor and IL-4 upregulated C5aR2 expression o

33 Stem cell factor and IL-6 were found to be minimal requi

34 te into CCA tumor microenvironment via c-Kit/stem cell factor and increase tumor progression, angioge

35 Stem cell factor and its receptor, KIT, are central to m

36 ggests a possible competition for the ligand Stem cell factor and offers the chance of curing early-s

37 activates transcription of the gene encoding stem cell factor and that mice lacking the cognate recep

38 volunteers were cultured in the presence of stem cell factor and thrombopoietin.

39 expansion in the presence of erythropoietin, stem cell factor, and dexamethasone.

40 wth factors, basic fibroblast growth factor, stem cell factor, and endothelin-3, along with exposure

41 actor, alpha-melanocyte stimulating hormone, stem cell factor, and fibroblast growth factor-2 in skin

42 of cytokines (interleukin-7, interleukin-15, stem cell factor, and fms-like tyrosine kinase-3 ligand)

43 Our previous work demonstrated that BMP4, stem cell factor, and hypoxia act in concert to promote

44 mbinations of dexamethasone, erythropoietin, stem cell factor, and interleukin-3.

45 early hemopoietic cytokines such as FLT3-L, stem cell factor, and M-CSF maybe relevant in LCH pathog

46 ial growth factor, fibroblast growth factor, stem cell factor, and stromal cell-derived factor-1, whe

47 B is required for mast cell migration toward stem cell factor, and that TGF-beta1 reduced this migrat

48 cl-2 upregulation, which was blocked by anti-stem cell factor antibody alone, the phosphatidylinosito

49 Erythropoietin and stem cell factor are the key cytokines that regulate ear

50 locyte-colony-stimulating factor (G-CSF) and stem cell factor at days 17 to 20 of parabiosis and were

51 Inhibition of CCA stem cell factor blocked MC migration and MC/EMT/ECM in

52 it expression when administered 3 days after stem cell factor, by which time surface Kit levels had r

53 Samd14-Enh stimulated stem cell factor/c-Kit signaling, which promotes erythro

54 matopoietic stem/progenitor cell regulation (stem cell factor/c-Kit), and c-Kit rescued Samd14 loss-o

55 m that depends, at the molecular level, on a stem cell factor/c-kit-mediated signaling axis.

56 ore, MSCs enhanced CSC proliferation via the stem cell factor/cKit and SDF1/CXCR4 pathways (P<0.0001)

57 Conversely, in the absence of IL-7 and stem cell factor, cNK cells were generated but ILC22 cel

58 the differentiation of interleukin-3 (IL-3)/stem cell factor (colony-forming unit [CFU]-IL3)-driven

59 fetal liver cells (FLC), erythropoietin- or stem cell factor-dependent Akt activation is greatly red

60 Moreover, proper stem cell factor-dependent cofilin activation via dephos

61 fibroma genesis, delineate the physiology of stem cell factor-dependent hematopoietic cells and their

62 The stem cell factor-dependent multipotent progenitor cell l

63 tor, growth hormone, parathyroid hormone, or stem cell factor each stimulates greater donor osteoblas

64 Treatment with the stem cell factor enhanced transcript levels of STIM1 and

65 and (CXCL)12-abundant reticular (CAR) cells, stem cell factor-expressing cells, nestin-expressing cel

66 and progenitor cells and reduced CXCL12 and stem cell factor expression in CAR cells but did not ind

67 AR cell development, upregulating CXCL12 and stem cell factor expression.

68 -fold reduction in response to a cocktail of stem cell factor, flt3 ligand, and thrombopoietin.

69 red on MS-5 stromal cells in the presence of stem cell factor, Flt3-L, interleukin 7 (IL-7), and IL-3

70 d up to 2 hours after their stimulation with stem cell factor, Fms-like tyrosine kinase 3 ligand, int

71 combinant mouse FLT3-L and recombinant mouse stem cell factor followed by recombinant mouse IL-5 alon

72 n vivo to directly activate transcription of stem cell factor FoxD3, initiating the neural crest prog

73 mal stem cell proliferation via its putative stem cell factor function, but it is not known if BMI1 m

74 of ML-ICs also correlated with increases in stem cell factor, GCSF, and IL-8 levels in AC-SCD compar

75 rent time points in controls (n=10) and upon stem cell factor gene transfer (n=13) after myocardial i

76 Stem cell factor gene transfer induces c-kit(+) stem/pro

77 mma(null)) mouse strain that expressed human stem cell factor, granulocyte-macrophage colony-stimulat

78 e-bound tyrosine kinase and the receptor for stem cell factor, has also been shown to play a critical

79 d C3orf58 as a novel hypoxia and Akt induced stem cell factor (HASF) secreted from mesenchymal stem c

80 overexpression of membrane-associated human stem cell factor (hSCF) enhances epicardial activation,

81 immunodeficient common gamma chain-deficient stem cell factor (huNSG) mice exhibited robust engraftme

82 on mutations in Kit receptors or Kit ligand (stem cell factor), ICC failed to develop in various regi

83 h of myeloid progenitors in an interleukin 3/stem cell factor (IL-3/SCF)-dependent manner in vitro wh

84 ony-stimulating factor or the combination of stem cell factor, IL-3, and IL-6.

85 Furthermore, in the presence of the stem cell factors, IL-33 did induce an MK2/3-, ERK1/2- a

86 pression of human GM-CSF, interleukin-3, and stem cell factor in a NOD/SCID-IL2Rgamma(null) backgroun

87 o measured significantly increased IL-16 and stem cell factor in KC saliva samples compared to health

88 hh produced in the dorsal region of the AGM, stem cell factor in the ventral and lateral regions, and

89 rine and human MCs and a regulatory role for stem cell factor in their expression.

90 growth factor, stromal-derived factor 1, and stem cell factor in tumor xenografts.

91 and ALDH1, the most significantly activated stem-cell factors in DCIS stem-like cells, are direct ta

92 stry, expression levels of the c-kit ligand, stem cell factor, in skin and epidermis are strongly inc

93 vascular cell adhesion molecule 1, SDF-1 and stem cell factor increased phospho-c-kit levels, and AMD

94 Moreover, growth factors including stem cell factor increased transcription of the Mcl-1 ge

95 Furthermore, stem cell factor induced LHPC proliferation, whereas gra

96 ted mast cells, absence of P38alpha inhibits stem cell factor-induced activation of Akt and ERK, whic

97 ith mature cells was selectively enhanced by stem cell factor-induced activation of GSK3beta.

98 ll progenitor cells as well as by regulating stem cell factor-induced migration of fully differentiat

99 mily genes and of transcriptional targets of stem cell factor-induced signaling.

100 Stem cell factor-induced survival of TC-32 cells was als

101 existence of a tissue microenvironment where stem cell factors influence cell survival, inflammation,

102 re performed with CCA cells treated with the stem cell factor inhibitor.

103 (VEGF), platelet-derived growth factor, and stem cell factor, inhibits ocular neovascularization in

104 t whereas Rac1 activity is up-regulated upon stem cell factor, integrin, or CXCL12 stimulation, R-Ras

105 or four cytokines (Flt3L + thrombopoietin + stem cell factor + interleukin 3).

106 , ESCs were cultured in methylcellulose with stem cell factor, interleukin (IL)-3, and IL-6.

107 ole for 3 hematopoietic stem cell cytokines: stem cell factor, interleukin-3, and stromal derived fac

108 ne-bound stem cell factor, releasing soluble stem cell factor into the cell culture supernatant at a

109 Stem cell factor is another important hematopoietic cyto

110 The KIT receptor whose ligand is the stem cell factor is necessary for mast cell development,

111 he erythropoietic factors erythropoietin and stem cell factor is preserved in CCBE1 null embryos, but

112 ore, addition of fibroblast growth factor or stem cell factor is unnecessary using 2i-LIF.

113 T activation, through binding of its ligand, stem cell factor, is crucial for normal mast cell growth

114 e transmembrane tyrosine kinase receptor for stem cell factor, is required for melanocyte and mast ce

115 th factor, platelet-derived growth factor B, stem cell factor (kit ligand), stromal-derived factor 1,

116 Kit receptor tyrosine kinase expression and stem cell factor/Kit signaling, while preventing respons

117 on MAPK signaling or on upregulation of the stem cell factor Klf4, whereas Pax6 upregulation was sig

118 nserved domains with the induced pluripotent stem cell factor Lin28 in mammals.

119 sis by activating NF-kappaB and inducing the stem cell factor Lin28B.

120 ession and in directly interacting with this stem cell factor, linking MUC1-C with function of the PR

121 atus: granulocyte colony-stimulating factor, stem cell factor, monokine induced by interferon-gamma (

122 iously that c-kit ligation by membrane-bound stem cell factor (mSCF) boosts IL-6 production in dendri

123 downstream target genes including well-known stem cell factors Nanog and Oct 3/4.

124 /Tai-dependent genes, including the germline stem cell factors nanos and piwi.

125 d up-regulation of stem cell markers (Bmi-1, stem cell factor, Notch-1, Nanog, nestin, ABCG2, and Oct

126 ved in invasion such as MMP9, PAI-1, and the stem cell factor OCT-3/4.

127 d on AhR and its ability to downregulate the stem cell factor Oct4.

128 f miR-34a and miR-145, which in turn repress stem cell factors OCT4, KLF4, LIN28A, and SOX2 and preve

129 C1s upregulates expression of the Kit ligand stem cell factor on these cells.

130 hosphorylation in mast cells stimulated with stem cell factor or interleukin-3, in serum-stimulated f

131 increased migratory behavior in response to stem cell factor or interleukin-8, which was associated

132 lacked mast cells through defects in either stem cell factor or its receptor, Kit.

133 We found a regenerative response because of stem cell factor overexpression characterized by an enha

134 .03); and decreased oncostatin M (P = 0.04), stem cell factor (P = 0.05), and stromal cell-derived fa

135 ween responders and non-responders including stem cell factor, platelet-derived growth factor, and in

136 ), the closest Xenopus homologs of mammalian stem cell factor Pou5f1 (Oct4).

137 nduced at least in part through upregulating stem cell factor production.

138 the activation of KIT following ligation by stem cell factor promotes a diversity of mast cell respo

139 Mechanistically, DAB2IP is able to suppress stem cell factor receptor (c-kit or CD117) gene expressi

140 Agents targeting stem cell factor receptor (C-KIT), platelet-derived grow

141 r binding protein-3 (IGFBP3), could modulate stem cell factor receptor (c-kit+), stem cell antigen-1

142 of Cajal (ICC) and often contain activating stem cell factor receptor (Kit) or platelet-derived grow

143 R), platelet-derived growth factor receptor, stem cell factor receptor (KIT), and colony-stimulating

144 s the Abelson (Abl), Arg (abl-related gene), stem cell factor receptor (Kit), and platelet-derived gr

145 o-B cells, particularly those expressing the stem cell factor receptor c-Kit, readily underwent apopt

146 GIST) patients who do not express the mutant stem cell factor receptor c-kit.

147 These were positive for the stem cell factor receptor c-kit.

148 (CSC) markers, including high levels of the stem cell factor receptor c-Kit.

149 ulation of the hyaluronate receptor CD44 and stem cell factor receptor CD117 (c-kit), a tyrosine kina

150 ess the hyaluronan receptor CD44, as well as stem cell factor receptor CD117 (c-kit).

151 Here we identify CD117 (c-kit, stem cell factor receptor) as a new marker of a rare adu

152 tor tyrosine kinase c-Kit, also known as the stem cell factor receptor, plays a key role in several d

153 of the related receptor tyrosine kinase KIT/stem cell factor receptor.

154 It also inhibits phosphorylation of Kit (stem-cell factor receptor) and platelet-derived growth f

155 as platelet-derived growth factor receptors, stem-cell factor receptor, glial cell line-derived neuro

156 platelet-derived growth factor receptor, and stem-cell factor receptor.

157 A and protein for soluble and membrane-bound stem cell factor, releasing soluble stem cell factor int

158 Kit receptor tyrosine kinase and its ligand, stem cell factor, respectively.

159 Poorer STAT5 inducers in culture (IL-4 or stem cell factor) result in less IL-13 production on IL-

160 The increased expression of stem cell factor resulted in Kit-mediated proliferative

161 cent young CSCs can be stimulated in situ by stem cell factor reversing the aging myopathy.

162 Here we examine the role of stem cell factor (SCF or Kit ligand) on the early- to mi

163 We have created a stable stem cell factor (SCF) -dependent human MC line, ROSA(KI

164 Stem cell factor (SCF) acts in synergy with antigen to e

165 cord blood-derived progenitors cultured with stem cell factor (SCF) alone express intragranular trypt

166 hage colony-stimulating factor (GM-CSF), and stem cell factor (SCF) also stimulated Nbs1 expression.

167 is identified a subset of secreted proteins (stem cell factor (SCF) and CCL5) induced by ErbB2 expres

168 he therapeutic effects of the combination of stem cell factor (SCF) and granulocyte-colony stimulatin

169 serial passage in liquid culture containing stem cell factor (SCF) and interleukin-3 (IL-3), produce

170 oduce mast cells when stimulated in vitro by stem cell factor (SCF) and interleukin-3 (IL-3).

171 Although stem cell factor (SCF) and its receptor c-kit are consti

172 progenitors are generally assumed to require stem cell factor (SCF) and KIT signaling during differen

173 but these effects were largely abolished by stem cell factor (SCF) and maximal suppression required

174 GF-I)-dependent production of membrane-bound stem cell factor (SCF) and may involve regeneration from

175 Despite their opposite effects on growth, stem cell factor (SCF) and transforming growth factor be

176 Interleukin-3 (IL-3) and stem cell factor (SCF) are important mast cell growth an

177 locyte colony-stimulating factor (G-CSF) and stem cell factor (SCF) are potential new therapies to am

178 of secretion upon c-jun deletion, identified stem cell factor (SCF) as a c-Jun target gene.

179 Surprisingly, stem cell factor (SCF) as the MC-supportive mediator par

180 Stem cell factor (SCF) binds and activates the receptor

181 Stem cell factor (SCF) binds to and activates the KIT re

182 ed in response to CCL2 when cultured in IL-3+stem cell factor (SCF) but not when cultured in IL-3 alo

183 Expression of stem cell factor (SCF) by these cells is necessary for t

184 Rb), bone morphogenic protein 4 (BMP-4), and stem cell factor (SCF) constituted a common cytokine sig

185 locyte colony-stimulating factor (G-CSF) and stem cell factor (SCF) could promote myocardial regenera

186 KIT K509I progenitors cultured in stem cell factor (SCF) demonstrated a 10-fold expansion

187 locyte-colony stimulating factor (G-CSF) and stem cell factor (SCF) in a humanized murine model of Fr

188 In the present studies the role of stem cell factor (SCF) in mediating eosinophil and fibro

189 exit correlates with an increase in soluble stem cell factor (SCF) in the serum, suggesting that the

190 Stem Cell Factor (SCF) initiates its multiple cellular r

191 Stem cell factor (SCF) is a cytokine important for the s

192 Stem cell factor (SCF) is a growth factor that acts thro

193 Stem cell factor (SCF) is a growth factor that is involv

194 Stem cell factor (SCF) is a molecule with known prolifer

195 While stem cell factor (SCF) is abundant in the CNS and is che

196 The receptor for stem cell factor (SCF) is expressed on mast cells and he

197 ies local neutralization of allergen-induced stem cell factor (SCF) leads to decreased production of

198 We demonstrate that stem cell factor (SCF) mRNA and protein are highly induc

199 e effects were reversed by neutralization of stem cell factor (SCF) or cell adhesion molecule 1 (CADM

200 est synergistic proliferation in response to stem cell factor (SCF) plus GM-CSF.

201 Stem cell factor (SCF) promotes synergistic cellular pro

202 ural analyses of the extracellular region of stem cell factor (SCF) receptor (also designated KIT) in

203 Both populations contain similar levels of stem cell factor (SCF) receptor (c-Kit) but only the CD3

204 xpressed at high levels in MCC tumors is the stem cell factor (SCF) receptor tyrosine kinase, c-Kit.

205 Stem cell factor (SCF) regulates MC development and viab

206 Neutralization of stem cell factor (SCF) secreted by leukemic cells inhibi

207 Most murine gastric ICC depend on stem cell factor (SCF) signaling but can also be maintai

208 tential repressor of gamma-globin gene after stem cell factor (SCF) stimulation in cultured human adu

209 a response that is potentiated by binding of stem cell factor (SCF) to its receptor Kit.

210 Stem cell factor (SCF) was secreted by differentiated tu

211 brane-bound tyrosine kinase and receptor for stem cell factor (SCF) with a crucial role in hematopoie

212 MCs was then correlated with skin levels of stem cell factor (SCF), a critical MC differentiation fa

213 Stem cell factor (SCF), a key factor in the propagation

214 Stem cell factor (SCF), a ligand of the c-kit receptor,

215 cursor cells resulted in potent induction of stem cell factor (SCF), an important pro-angiogenic fact

216 ice after stimulation with the c-Kit ligand, stem cell factor (SCF), an important regulator of mast c

217 nt, and are exposed to interleukin-6 (IL-6), stem cell factor (SCF), and chemokines such as CXCL12 (O

218 K(4) (palmitoyl-3-cysteine-serine-lysine-4), stem cell factor (SCF), and cross-linked IgE, respective

219 or CML CD34+ cells supplemented with G-CSF, stem cell factor (SCF), and granulocyte macrophage-colon

220 e myeloid-activating factors erythropoietin, stem cell factor (SCF), and hepatocyte growth factor (HG

221 ed negatively by the mast cell growth factor stem cell factor (SCF), and its expression was not detec

222 erived factor-1 (SDF-1), its receptor CXCR4, stem cell factor (SCF), and its receptor c-Kit on sectio

223 cultures and the addition of thrombopoietin, stem cell factor (SCF), and macrophage colony stimulatin

224 tin (EPO) plus the growth-modifying cytokine stem cell factor (SCF), and several growth-related signa

225 Upon binding its ligand, stem cell factor (SCF), c-Kit forms an active dimer that

226 show that activation of c-Kit by its ligand, stem cell factor (SCF), cooperates with alpha4 integrin

227 Stem cell factor (SCF), erythropoietin (Epo), and GATA-1

228 rogenitors with interleukin 7 (IL-7), IL-15, stem cell factor (SCF), FLT-3L, and murine fetal liver c

229 Treatment with stem cell factor (SCF), Flt3-ligand (FL), IL-3, and GM-C

230 adult mice were cultured in the presence of stem cell factor (SCF), interleukin 3 (IL-3), IL-7, gran

231 is activated after wild-type (WT) Kit binds stem cell factor (SCF), is constitutively active in cell

232 The KIT ligand, stem cell factor (SCF), is critical for mast cell expans

233 ytokines such as interleukin-3 (IL-3), IL-7, stem cell factor (SCF), macrophage-colony-stimulating fa

234 EGF), platelet-derived growth factor (PDGF), stem cell factor (SCF), macrophage-stimulating protein (

235 surface expression of c-Kit and its ligand, stem cell factor (SCF), on DCs.

236 ting factor (G-CSF)+Flt-3 ligand (FL), G-CSF+stem cell factor (SCF), or G-CSF alone starting 4 hours

237 Receptor tyrosine kinase Kit and its ligand, stem cell factor (SCF), play a critical role in the grow

238 Kit, the receptor for stem cell factor (SCF), plays a critical role in the pro

239 in promoting chemotaxis of mast cells toward stem cell factor (SCF), the ligand for KIT receptor.

240 Here, we show that stem cell factor (SCF), the ligand for KIT, induces the

241 or bone marrow (BM) HSCs using low levels of stem cell factor (SCF), thrombopoietin (TPO), insulin-li

242 preconditioning increases the expression of stem cell factor (SCF), which is critical for HSC engraf

243 hematopoietic repopulating cells from either stem cell factor (SCF)- and granulocyte-colony stimulati

244 his study, we provide evidence that blocking stem cell factor (SCF)-c-kit signaling is sufficient to

245 o determine the effect of these cytokines on stem cell factor (SCF)-dependent human mast cell product

246 t E2a/Pbx1 induces immortal proliferation of stem cell factor (SCF)-dependent pro-T thymocytes by a m

247 tosis in cultured human MCs, which depend on stem cell factor (SCF)-induced or constitutive KIT activ

248 The decrease in stem cell factor (SCF)-mediated survival in the GSK3beta

249 responses correlated with the inhibition of stem cell factor (SCF)-stimulated activation of extracel

250 ch was largely independent of the effects of stem cell factor (SCF).

251 e that can be maintained in medium including stem cell factor (SCF).

252 PC mobilization with Flt3 ligand (Flt3L) and stem cell factor (SCF).

253 e and in complex with its activating ligand, stem cell factor (SCF).

254 largely controlled by the cytokines IL-3 and stem cell factor (SCF).

255 high transcript levels of Rars, Cxcl12, and stem cell factor (Scf).

256 ctor (G-CSF), or a combination of G-CSF plus stem cell factor (SCF).

257 isolated and placed in culture with IL-3 and stem cell factor (SCF).

258 n the absence of the natural ligand for KIT, stem cell factor (SCF).

259 cifically blocks binding of the c-kit ligand stem cell factor (SCF).

260 i-c-kit antibody, suggesting that endogenous stem cell factor (SCF)/c-kit interaction synergizes with

261 In this study, through analysis of the stem cell factor (SCF)/c-kit ligand receptor pair, we de

262 t the gamma position plus stimulation of the stem cell factor (SCF)/c-Kit pathway yielded high levels

263 The stem cell factor (SCF)/Kit system has served as a classi

264 equires the stimulation of axon outgrowth by Stem Cell Factor (SCF, also known as Steel Factor).

265 d activation are regulated, respectively, by stem cell factor (SCF; also known as Kit ligand) and by

266 Stem cell factor (SCF; also known as KITL) is a key nich

267 Among the candidate factors, stem- cell factor (SCF) is expressed by various human an

268 (caspase-8) and proliferation (IL-6, IL-15, stem cell factor [SCF]).

269 ptor [-R], AKT2, phosphorylated AKT [p-AKT], stem cell factor [SCF], and PDGF) were performed.

270 5) in response to 5 cytokine/growth factors (stem cell factor [SCF], Flt-3/Flk-2 ligand [FL], granulo

271 etic cytokines (interleukin-7 [IL-7], Flt3L, stem cell factor [SCF], ThPO, and IL-6) from bone marrow

272 d the obligate growth factor for mast cells, stem cell factor, SCF, is not induced.

273 by the actions of c-Kit ligand (also called stem cell factor; SCF) and fetal liver kinase 2 ligand (

274 ge colony-stimulating factors (GM-CSFs), and stem cell factors (SCFs) may be candidate treatments for

275 Pretreatment of mBMMCs with stem cell factor significantly down-regulated expression

276 -regulatory pathway cooperate to recruit the stem cell factor SOX2 in expanding and sustaining the ac

277 Expression of the stem cell factor SOX2 was repressed by DACH1, and SOX2 e

278 phenotype involves its ability to induce the stem cell factor SOX2.

279 f a set of genes, including most notably the stem cell factor SOX9, that promote proliferation and a

280 In line with these activities, upon stem cell factor stimulation, murine bone marrow-derived

281 st cells, and these were further enhanced by stem cell factor stimulation.

282 trastructural features and dependency on Kit/stem cell factor system.

283 ransgenic expression of human membrane-bound stem cell factor Tg(hu-mSCF)] would increase levels of h

284 Thus, Mam, like Hh, is a crucial stem cell factor that acts selectively on FSCs in the ov

285 Cdx2 competes with Oct4, a stem cell factor that determines commitment to the embry

286 Cdx2, a stem cell factor that determines commitment to the extra

287 rom Lgr5(+) stem cells, which expressed Kitl/stem cell factor, the ligand for cKit.

288 lation with a mixture containing IL-3, IL-6, stem cell factor, thrombopoietin, and Flt3 ligand induce

289 , and urticaria, is used in conjunction with stem cell factor to generate CD34(+) cell-derived primar

290 s not known if BMI1 may also act as a cancer stem cell factor to promote cancer development.

291 tion as receptors of the R-spondin family of stem cell factors to potentiate Wnt/beta-catenin signali

292 mma chain (gammac(-/-)) and carrying a human stem cell factor transgene were engrafted with human hem

293 c-endothelial signaling, including neuritin, stem cell factor, vascular endothelial growth factor (VE

294 ro culture of bone marrow cells in IL-3 plus stem cell factor, we found that the addition of IFN-gamm

295 Cholangiocytes secrete stem cell factor, which functions via the MC growth fact

296 hage colony-stimulating factor (GM-CSF) plus stem cell factor, which was partially blocked by Survivi

297 hwann cells or ST88-14 cells stimulated with stem cell factor, whose receptor is also overexpressed i

298 HuMCs were cultured in stem cell factor with or without IL-6.

299 viable mast cells after culture in IL-3 plus stem cell factor, with profound apoptosis occurring as t

300 a group of three proteins (Apo AI, IL-12 and stem cell factor) yielded accuracy of 81.3%, sensitivity