ライフサイエンスコーパス: stem-loop

1 uence, a slippery sequence, and a downstream stem loop.

2 IRP1 interaction with the H-ferritin IRE RNA stem loop.

3 ucture of the phylogenetically conserved ISS stem loop.

4 RNA can be replaced by this U6atac distal 3' stem-loop.

5 ally distinctive, lacking the essential P6.1 stem-loop.

6 pecific requirements for the frameshift site stem-loop.

7 thylene blue-labeled structure-switching DNA stem-loop.

8 the HIV-1 trans-activation response element stem-loop.

9 stability of a simple, surface-attached DNA stem-loop.

10 e more frequent in the absence of a relevant stem-loop.

11 re not polyadenylated but end in a conserved stem-loop.

12 and carrier sequences stabilized by a miR-30 stem-loop.

13 llustrates the recognition of unbranched RNA stem loops.

14 cent transcripts were visualized via MS2 RNA stem loops.

15 transcripts containing 5' MS2 and 3' PP7 RNA stem loops.

16 ve structures comprising either four or five stem-loops.

17 A, we found that extending the tetraloop and stem loop 2 of the sgRNA with MS2 or PP7 aptamers enhanc

18 RM binds the 3' end of 7SK RNA at the top of stem-loop 4 (SL4) and interacts with both unpaired and b

19 Here, we report a new interaction between stem-loop 4 (SL4) of the U1 snRNA, which recognizes the

20 U112A mutation to maintain a uORF-harboring stem-loop 4 structure, an unimpaired virus with wild-typ

21 30, or 51 nucleotides (nt) were made within stem-loop 4, viable but debilitated virus was recovered.

22 RP6 is a protein which directly binds the 5' stem-loop (5'SL) present in collagen alpha1(I) and alpha

23 In particular, stem-loop A (SLA) and stem-loop B (SLB) located in the 5

24 Stem-loop A (SLA), a part of the viral 5' untranslated r

25 VAI consists of an apical stem-loop, a highly structured central domain, and a ter

26 VAI contains three domains: an apical stem-loop, a highly structured central domain, and a ter

27 In Db-PCR, 5'- and 3'-stem-loop adapters are specifically hybridized and ligat

28 ing the entire assembly, but the U4 snRNA 5' stem-loop adopts alternative orientations each stabilize

29 DNA fragments can also be detected at 5' end stem-loops, although at much lower frequency.

30 MEPCE is dependent on the structure of the 3 stem loop and the closed form of 7SK RNA.

31 he impact of several key components of miRNA stem loops and their flanking sequences on the efficienc

32 Two types of structural element, a stem-loop and a poly(G) motif, not only inhibit translat

33 sed of ROQ and HEPN domains, and can bind to stem-loop and double-stranded RNAs simultaneously.

34 tem-loop binding protein (SLBP) binds to the stem-loop and is required for all steps in histone mRNA

35 mic structural rearrangements between tandem stem-loop and mRNA pseudoknot structures in two of the s

36 Stem-loop-binding protein (SLBP) binds the stem-loop and regulates canonical histone mRNA metabolis

37 from the 5'-UTR, including the terminator 5'-stem-loop and Shine-Dalgarno blocking hairpins, demonstr

38 e-stranded region of U4 snRNA between its 3' stem-loop and the U4/U6 snRNA stem I is loaded into the

39 One product mapped to a predicted 5'-SL (stem-loop) and two others mapped just 5' to Shine-Dalgar

40 tures, the cleavage site is sequestered in a stem-loop, and gene expression is unobstructed.

41 viral genome, built atomic models for 16 RNA stem-loops, and identified three conserved motifs of RNA

42 roRNAs (miRNAs), processed from mRNA forming stem-loops; and (2) small interfering RNAs (siRNAs), the

43 croRNAs representing the miR-143 and miR-145 stem loops are genomically clustered.

44 h the sequences and the structure of the two stem-loops are important for CRD-BP-GLI1 RNA binding.

45 Here, we used a stem-loop array reverse-transcription polymerase chain r

46 tion initiating with oligouridylation of the stem loop at the 3' end.

47 The stem-loop at the 3' end of the genome interacts extensiv

48 ication of U2605 to pseudouridine (Psi) in a stem-loop at the peptidyl transferase center of Escheric

49 Genetic ablation of the miR-21 stem loop attenuated neointimal formation in mice post-s

50 he 3'UTR, where it binds an adjacent AU-rich stem-loop (AUSL) element, "flipping" the RNA switch by d

51 In particular, stem-loop A (SLA) and stem-loop B (SLB) located in the 5' untranslated region

52 ant by introducing an additional copy of the stem-loop between the NS7- and VP1-coding regions.

53 Stem-loop binding protein (SLBP) binds to the stem-loop

54 The stem-loop binding protein (SLBP) specifically recognizes

55 This specialized 3' end is bound by stem-loop binding protein (SLBP), a protein that partici

56 eduction was correlated with lower levels of stem-loop binding protein (SLBP), which is known to cont

57 SLBP (stem-loop binding protein) is a highly conserved factor

58 eveals that eIF3 uses different modes of RNA stem-loop binding to exert either translational activati

59 Stem-loop-binding protein (SLBP) binds the stem-loop and

60 a conserved stem loop that is recognized by stem-loop-binding protein (SLBP).

61 and Cy5 on dsRNA, using complexes of an RNA stem-loop bound to L5 protein determined at 2.4 A resolu

62 potentially folds into a single long stable stem-loop by pairing of intron 0 and part of exon 2.

63 During cDNA synthesis, RNA 3' end stem-loops can self-prime reverse transcription, creatin

64 anism mediated by spontaneous extrusion of a stem-loop catalytic intermediate.

65 nslated region (UTR) of NT8 contains a short stem-loop cis-element that is necessary for the regulati

66 aged single beta-actin mRNAs tagged with MS2 stem loops colocalizing with labeled ribosomes to determ

67 nigenomic RNA indicates formation of a small stem-loop composed of the HSPA8 motif, a 3' stem-loop (n

68 V-1 primer binding site, (-)PBS, both in its stem loop conformation and in the corresponding (-)/(+)P

69 re, involving the recognition of ssRNA via a stem-loop conformation, together with our two previous s

70 aled that the aptamers formed stable B-form, stem-loop conformations.

71 In bulge-stem-loop constructs of HIV-1 transactivation response e

72 ination, we targeted LRV1 using long-hairpin/stem-loop constructs similar to those effective against

73 binding domain, and a downstream inhibitory stem-loop containing the sRNA and ribosome binding sites

74 The second stem-loop contains conserved sequences required for base

75 tional Rev/RRE activity compared to the four stem-loop counterpart.

76 SmRNA in comparison with an mRNA lacking the stem loop, DeltaSL.

77 itative analysis showed that the stimulatory stem loop destabilizes the hybrid state and elevates the

78 eleting or disrupting the two conserved GRPE stem loops diminished gRNA packaging and infectivity >50

79 The helical axis of the GUAAY stem loop diverges ~70 degrees from the angle of inserti

80 c detection - and their incorporation onto a stem loop DNA probe.

81 system is based on a conformation-switching stem-loop DNA scaffold that presents a small-molecule, p

82 MAmer, comprised of a G-quartet domain and a stem-loop domain, engages IL-6 in a clamp-like manner ov

83 35-nt 5' UTR, is characterized by functional stem loop domains responsible for regulating the viral l

84 report that the HalV 5' UTR comprises small stem-loop domains separated by long single-stranded area

85 loop; both structures adopt a novel hairpin (stem-loop duplex) conformation in the long loop.

86 A DIG tag on one arm of the stem loop enables binding to the magnetic label, while a

87 The Psi domain is extended, with each stem loop exposed for interactions with binding partners

88 Through randomizing bases in anticodon stem-loop followed by a functional selection, we identif

89 of single-stranded elements of the pri-miRNA stem-loop followed by Drosha recruitment and pri-miRNA c

90 transcripts (pri-miRNAs), with the choice of stem loops for initial processing largely determining wh

91 ication assays, we demonstrate that the five stem-loop form of the RRE promotes greater functional Re

92 hown to mediate efficient nascent transcript stem loop formation-dependent RNA-DNA hybrid realignment

93 n Qrr4 vital for stability, Hfq interaction, stem-loop formation, and base pairing to both luxR and l

94 We have identified a potential mRNA stem-loop forming structure in the 5' untranslated regio

95 ven stem-loop structures, with the 5' and 3' stem-loops forming an essential bipartite signal.

96 ng by the 3'-UTR was dependent on a putative stem-loop-forming region previously associated with rapi

97 The 4-residue loop of this stem-loop-forming sequence shows the highest incidence o

98 ependent RNA polymerase, confirming that the stem-loop forms the core of the norovirus subgenomic pro

99 newal, DDX6 associates with YBX1 to bind the stem loops found in the 3' UTRs of regulators of prolife

100 f the HIV type 1 (HIV-1) RNA frameshift site stem-loop, frameshift efficiency, and infectivity, using

101 on to the study of targeted oxidation of RNA stem loops from HIV-1 Rev Response Element mRNA (RRE RNA

102 The fourth stem-loop functions as a rho-independent terminator.

103 c stability, high repetitiveness, and stable stem-loop/hairpin secondary structures that are hallmark

104 The RluB-bound stem-loop has essentially the same secondary structure a

105 Though the structure of the substrate stem loop I (SLI)-stem loop V (SLV) kissing loop junctio

106 inding (Kd = 120 +/- 10 nm) to the conserved stem-loop I of the 3'-BTE by exposing more unpaired base

107 aled that the 5'U-Ubulge and central loop of stem-loop I or RNA motif 3 of 7SK are required for trans

108 Since 5' stem-loop I RNA forms a ribonucleoprotein complex with c

109 These deletions lacked portions of 5' stem-loop I, which is an RNA secondary structure require

110 part through specific interactions with its stem loop II (SLII) IRES domain.

111 thylation of two conserved adenosines in the stem loop II region of HIV-1 Rev response element (RRE)

112 We also present evidence that vsRNA1 targets stem-loop II of the viral 5' untranslated region and inh

113 een the two 5'UTRs in the highly substituted stem-loop II region (SLII).

114 are also presented, wherein the Rev-binding stem-loops (IIB and I) are located coaxially in the form

115 Destabilization of the stem-loop immediately upstream of the pyrimidine-tract a

116 Cloning of the precursor stem loop, immunoprecipitations, ectopic expression and

117 itate their processing and also an essential stem loop in bunyaviral RNA to restrict infection.

118 ed new enhancer RNA elements and an extended stem-loop in the NS5B coding region.

119 d requirement of a substructure of U6atac 3' stem-loop in U12-dependent in vivo splicing.

120 t cyclin F co-evolved with the appearance of stem-loops in vertebrate H2AFX mRNA to mediate SLBP degr

121 ic domain of RluB and the isolated substrate stem-loop, in which the target uridine is substituted by

122 , DDX17 has dual roles in the recognition of stem loops: in the nucleus for endogenous microRNA (miRN

123 conserved helix 8 contains an unprecedented stem-loop insertion.

124 ix 8 alterations including single and double stem-loop insertions as well as loop diminutions affecti

125 Reporter assays confirmed that cap-distal stem-loop insertions increase dependence on Ded1 but not

126 ing conversion of metastable, intramolecular stem-loops into more stable heteroduplexes.

127 Qrr sRNAs possess four stem-loops: the first stem-loop is crucial for base pairing with a subset of t

128 We demonstrate that the conserved stem-loop is essential for MNV viability.

129 The conserved stem-loop is positioned 6 nucleotides 3' of the start si

130 d that it, possibly in concert with adjacent stem-loops, is a cis-acting replication signal in the (+

131 actions with the U6 ACAGAGA, the U6 internal stem loop (ISL) and the U2-U6 helix I, all RNA elements

132 t all four isoforms of AUF1 bind directly to stem-loop IV of the poliovirus 5' NCR, an interaction th

133 use of sgRNAs truncated for the 3'-terminal stem loops leads to reduced activity during genomic edit

134 r, poly-A-containing arms flanking the miRNA stem-loop markedly enhanced transgenic miRNA expression.

135 he temperature-dependent TSS selection and a stem-loop masking of ribosome binding sites was predicte

136 The only previous proposal of stem loop mediated slippage, which was in Ebola virus ex

137 tes yeast and mammalian ribosomes and an RNA stem-loop mimic of the sarcin/ricin loop (SRL) at a high

138 after stenting in pigs, including the miR-21 stem loop miRNAs.

139 l predicted sites within the 'stem' when the stem-loop model was first proposed and no mutations have

140 onstrate the potential importance of the two-stem-loop motif as a target region for the inhibition of

141 g of phosphorylated SLBP to the histone mRNA stem-loop motif followed by association with SLIP1 is re

142 The role of the two-stem-loop motif in influencing CRD-BP-RNA interaction wa

143 LARP6 binds a stem-loop motif in the 5'-UTR of the mRNAs encoding the

144 ent (CTE), a cis-acting 2-fold symmetric RNA stem-loop motif.

145 tions of the three most abundant hyperstable stem loop motifs represents a significant milestone to t

146 y junction (FWJ) and its appropriate control stem-loop motifs (Dumbbell, GAAATT-Hp, CTATC-Hp, GTGC-Hp

147 en-J) junction and their appropriate control stem-loop motifs (GAAATT-Hp, CTATC-Hp, and Dumbbell).

148 d-J and Open-J with those of their component stem-loop motifs allowed us to be more specific about th

149 he 50S subunit E site, while their anticodon stem loops move with the head of the 30S subunit to posi

150 A given rRNA helix or stem-loop must be allocated uniquely to a single domain.

151 We found a c.915+15A>C exon 10/intron 10 stem loop mutation in all affected subjects but not in t

152 Eleven MAPT gene splice site stem loop mutations were identified over time except for

153 stem-loop composed of the HSPA8 motif, a 3' stem-loop (nucleotides 1868-1890) that is similar to a p

154 rmined that the xRRM of LARP7 binds to the 3 stem loop of 7SK and inhibits the methyltransferase acti

155 ing (CLIP-seq), we show that DDX17 binds the stem loops of host pri-miRNA to facilitate their process

156 Mutation of the 5' stem-loop of Col1a1 mRNA, which inhibits binding of LARP

157 ry activity of SRA RNA by binding a specific stem-loop of SRA.

158 The anticodon stem-loop of the A-site tRNA is captured in transition t

159 demonstrate that p65 protein-binding apical stem-loop of U12 snRNA can be replaced by this U6atac di

160 binding protein, also binds to the distal 3' stem-loop of U6atac.

161 o obtain l-RNA aptamers that bind the distal stem-loop of various precursor microRNAs (pre-miRs).

162 can act by pairing with ribosomal RNA or as stem loops or pseudoknots even with one component being

163 sin-V dimer "walking" on an actin fibre, RNA stem-loop packing, and the simulation of cell motion and

164 Moreover, experimental investigation through stem-loop PCR of a random collection of newly discovered

165 The third stem-loop plays an accessory role in base pairing and st

166 ds out among these miRNAs because its entire stem-loop precursor overlaps the coding sequence for the

167 de RNAs, some of which are predicted to have stem-loop precursors potentially representing miRNAs.

168 fied 145 miRNAs along with the corresponding stem-looped precursors with many differentially expresse

169 nse oligonucleotide, containing two distinct stem-loops present in nts 320-380 of GLI1 RNA, was found

170 Key to this method is a modified stem loop primer that facilitates downstream signal ampl

171 signal 20-fold when compared to traditional stem loop primers.

172 7 (m(1)G37) modification-deficient anticodon stem loop(Pro), both of which cause the ribosome to deco

173 For both stem-loop probe and linear probe electrochemical DNA sen

174 To increase target miRNA specificity, a stem-loop probe was introduced instead of a linear probe

175 oelectrodes in the fabrication of linear and stem-loop probe-based electrochemical DNA (E-DNA) sensor

176 Second, an additional RNA stem-loop promotes Rho activity and controls the locatio

177 expressed during S-phase end in a conserved stem-loop rather than a polyA tail.

178 rophores or affinity labels into a short RNA stem loop recognition motif by exchange of a guanine res

179 -function properties of the H5 hemagglutinin stem loop region by site-directed mutagenesis.

180 The highly conserved stem loop region of hemagglutinin has been shown to unde

181 ese studies underscore the importance of the stem loop region to HA function and suggest potential si

182 Helix 69 (H69) is a 19-nt stem-loop region from the large subunit ribosomal RNA.

183 u1 specifically interacted with the variable-stem-loop region in the 3' NTR and domain IIId of the HC

184 Our previous work demonstrated that the 3' stem-loop region of U6atac snRNA contains a U12-dependen

185 miRNAs, including the sequences flanking the stem-loop region, contributed to high affinity EWS bindi

186 As) are small regulatory RNAs processed from stem-loop regions of primary transcripts (pri-miRNAs), w

187 Mutant MNV RNAs with substitutions in the stem-loop replicated poorly until they accumulated mutat

188 RNA stem loops represent an important class of known hnRNP A

189 esp. HCV] contribute to the formation of the stem-loop [resp. double stem-loop] secondary structure k

190 RNA and mRNA profiling using high throughput stem-loop reverse-transcriptase quantitative polymerase

191 ts with severe asthma using high-throughput, stem-loop, reverse transcriptase quantitative real-time

192 Furthermore, overexpression of a 5' stem-loop RNA molecular decoy that sequesters LARP6, pre

193 The SECIS element is a stem-loop RNA structure immediately following the UGA co

194 ements), and form a thermodynamically stable stem-loop secondary structure (structure requirement).

195 lippery sequence and an immediate downstream stem-loop secondary structure, together called frameshif

196 ic-C target site is predicted to fold into a stem-loop secondary structure.

197 the formation of the stem-loop [resp. double stem-loop] secondary structure known as the frameshift s

198 We conclude that the extra stem-loop sensitizes this RNA to broaden the dynamic ran

199 mulated mutations that revert to restore the stem-loop sequence and/or structure.

200 The stem-loop sequence functions in a noncoding context, as

201 , in vitro biochemical data suggest that the stem-loop sequence is sufficient for the initiation of v

202 n via an RNA-binding protein that recognizes stem-loop sequences engineered into the viral genome.

203 sMIR390-based precursors that include distal stem-loop sequences from Arabidopsis thaliana MIR390a (A

204 ary structural elements, only a single 15-nt stem-loop showed a strong correlation with splicing, act

205 cture of QueG bound to a tRNA(Tyr) anticodon stem loop shows how this enzyme uses a HEAT-like domain

206 R/sfRNA of the wild-type virus mapped to RNA stem-loops SL-III and 3' SL, which stick out of the thre

207 ding the transcription factor Xbp1 at a dual stem-loop (SL) structure, leading to Xbp1 splicing and a

208 small stem-loop (SSL) and an 80-nt terminal stem-loop (SL).

209 c sRNAs, Pxr is predicted to fold into three stem loops (SL1-SL3).

210 The structure is composed of two stem-loops (SLs) that are predicted to form in MYB33/65

211 ) genomic RNA form a penultimate 16-nt small stem-loop (SSL) and an 80-nt terminal stem-loop (SL).

212 n enzyme that cleaves double-stranded RNA or stem-loop-stem RNA into 20-25 nucleotide long small RNA,

213 ing the interaction of a West Nile virus RNA stem loop structure with the human T cell-restricted int

214 terminal capsid coding region, including the stem-loop structure (5'SL6) at the 3' end of the promote

215 While an RNA stem-loop structure (the "HIV-1 Frameshift Stimulating S

216 The noise-enhancing effect of the stem-loop structure also remains operational when combin

217 Instead, the histone mRNAs display a stem-loop structure at their 3'-end.

218 abels to monitor changes in the mini TAR DNA stem-loop structure brought on by the HIV-1 nucleocapsid

219 The ENE, a stem-loop structure containing a U-rich internal loop, i

220 ial RNA polymerases (RNAPs) encode a GC-rich stem-loop structure followed by a polyuridine [poly(U)]

221 DICER cleaves the stem-loop structure from pre-miRNAs, allowing them to di

222 s sequence, translation activity relies on a stem-loop structure identified at nucleotide positions 4

223 tically, MCPIP1 physically interacted with a stem-loop structure in the 3' untranslated region of the

224 n a kissing interaction with a complementary stem-loop structure in the 3' UTR.

225 We previously characterized SLC, a stem-loop structure in the 5' untranslated region (UTR)

226 Our results suggest that the stem-loop structure in the vacA 5' UTR is an important d

227 e local stability of the frameshift site RNA stem-loop structure increase frameshift efficiency 2-fol

228 V particles, was sequestered in an alternate stem-loop structure inside immature virions.

229 replication-dependent histone mRNAs end in a stem-loop structure instead of the poly(A) tail characte

230 ational analyses provided evidence that this stem-loop structure is important for Bic-C binding.

231 presence of an evolutionarily conserved RNA stem-loop structure on the negative-sense RNA, the compl

232 mutagenesis, we found that disruption of the stem-loop structure reduced steady-state mRNA levels bet

233 ere we describe the identification of an RNA stem-loop structure that functions as the core of the no

234 protected" by the steric hindrance of the MB stem-loop structure, accessible.

235 existence of a preferred binding site in the stem-loop structure, in which ametantrone intercalates i

236 e linked to cycles of folding/unfolding of a stem-loop structure, or to interconversion between highe

237 ic translational machinery that recognizes a stem-loop structure, the SECIS element, at the 3' UTR of

238 ensity of the expanded CAG repeats to form a stem-loop structure.

239 ement when present in the unpaired loop of a stem-loop structure.

240 ranslation of reporter luciferase mRNAs with stem-loop structured or unstructured 5'-UTR.

241 tructures for these RNA molecules, including stem-loop structures and long-range pseudoknots.

242 The sites of truncation coincide with stem-loop structures and SRP9/14 binding sites in the Al

243 s within these transcripts predicted to form stem-loop structures are processed by Microprocessor and

244 -derived sequences with predicted stem-bulge-stem-loop structures are sufficient to mediate mRNA tran

245 The switch mechanism relies on two putative stem-loop structures contained within the 5' untranslate

246 From six vsRNAs, with candidate stem-loop structures in the 5' and 3' untranslated regio

247 in Escherichia coli that result in extensive stem-loop structures in their mRNAs.

248 Isoforms engineered to fold into 3' stem-loop structures not involving the poly(A) tail exhi

249 nking short base-paired DNA stretches, as in stem-loop structures of single-stranded DNA (ssDNA) deri

250 resent, NCp7 enhanced the annealing of their stem-loop structures to form duplex DNA-RNA.

251 Finally, stem-loop structures with similar configurations were id

252 in plants rely extensively on the search for stem-loop structures, leading to high false negative rat

253 hown to cleave within 3'-untranslated region stem-loop structures, which contain double-stranded RNA,

254 led a highly structured RNA comprising seven stem-loop structures, with the 5' and 3' stem-loops form

255 strictly conserved sequences and form stable stem-loop structures.

256 and antisense members, all of which contain stem-loop structures.

257 RNA transcripts that contain precursors with stem-loop structures.

258 to favor formation of one of two alternative stem-loop structures.

259 ound at sites encoding unpaired bases of RNA stem-loop structures.

260 in these RNA molecules are predicted to form stem-loop structures.

261 nserved terminal loop motif within short RNA stem-loop structures.

262 The conserved existence of a third stem-loop suggested an important hitherto unknown functi

263 Mutational analysis of these stem loops supports a model in which induction of an alt

264 binding surface to recognize the base of its stem-loop target RNA and extends a newly-formed alpha he

265 ence elements of several native hnRNP A1-RNA stem loop targets.

266 We describe the final missing stem loop tau mutation predicted 15 years ago.

267 cytosines in an upstream, EvoFold-predicted stem loop (termed ESL) that binds FUBP1/2.

268 The template-distal domain is a short stem-loop, termed equivalent CR4/5 (eCR4/5).

269 As f and C are changed, the stem-loop tertiary interactions rupture first, followed

270 dependent histone mRNAs end with a conserved stem loop that is recognized by stem-loop-binding protei

271 ing at different sites of the 3' side of the stem loop that resulted from initial degradation by 3'hE

272 ingle sgRNA, modified to contain MS2-derived stem loops that recruit fusion proteins consisting of th

273 equired the proper spatial organization of a stem-loop that is mainly determined by the U-rich elemen

274 ta suggest that 3D interacts in cis with RNA stem-loops that are essential for viral RNA replication.

275 of dispersed assembly signals in the form of stem-loops that each present a minimal CP-binding motif

276 in modular domains consisting of one or more stem-loops that harbor conserved RNA motifs critical for

277 that all five of the Qrr sRNAs possess four stem-loops: the first stem-loop is crucial for base pair

278 -binding motif, the relative placement of PS stem-loops, their number, and their folding propensity.

279 y of the RNA structure, the proximity of the stem loop to the slippage site, the length and compositi

280 from the ligand-binding pocket, exposing its stem-loop to base pair with the 3' RBS.

281 and for the detailed structural change from stem-loop to duplex RNA-DNA when complementary RNA was p

282 ement), that regulated levels of all pri-miR stem loop transcription and resulting microRNA expressio

283 At high temperatures, the stem-loop unfolds, allowing for mRNA degradation and tur

284 for recognition, and reveals changes in the stem-loop upon protein binding.

285 structure of the substrate stem loop I (SLI)-stem loop V (SLV) kissing loop junction of the Varkud Sa

286 The stem-loop was systematically altered to decouple the con

287 covery of a "hit" molecule able to bind this stem-loop, we now report the development of compounds di

288 of potential cis-acting elements within the stem-loop were evaluated using the reporter assay in two

289 respectively, the stabilising effects of the stem-loop were even more pronounced.

290 ncoming sRNAs without opening the inhibitory stem-loop when sRNA is absent.

291 The MicA structure contains two stem loops, which impede its interaction with target mRN

292 dynamic stability of the first 3-4 bp in the stem-loop, which are predicted to reside at the opening

293 y that completely unfolds the tRNA anticodon stem-loop, which is likely critical for recognition of b

294 uses an oligodeoxynucleotide that folds to a stem-loop with a TG-rich double-stranded region and a 3'

295 t has been proposed that steric clash of the stem-loop with the exit pore of the RNAP imposes a shear

296 These RNAs form stem-loops with a conserved loop motif that trigger sequ

297 condary structures of these regions revealed stem-loops with conservation of structure and a common m

298 -coat protein interactions among 15 of these stem-loops with diverse sequences.

299 ied clustered hyperediting within long dsRNA stem loops within 3' untranslated regions of endogenous

300 agen synthesis and interacts with a specific stem-loop within the 5' UTR of the collagen mRNA.