ライフサイエンスコーパス: stenotic

1 in acute myocardial infarction are severely stenotic.

2 c strain identifies which coronary artery is stenotic.

3 us UEI normalized strain also differentiated stenotic (-0.87) versus adjacent normal small bowel (-1.

4 Fifteen vessels were severely stenotic and 13 were completely occluded.

5 Luminal diameters of stenotic and adjacent vessel segments before and after a

6 functional repertoire of T cells differs in stenotic and aneurysmal lesions, and provide a novel fra

7 sham surgery (n = 5) was performed, and the stenotic and contralateral kidneys were studied longitud

8 s similarly detected the differences between stenotic and contralateral kidneys.

9 ulture, and to study the differences between stenotic and nonstenosed stents.

10 Stenotic and nonstenotic contralateral kidneys were comp

11 CD were studied with UEI and their resected stenotic and normal bowel segments were evaluated by ex

12 The myocardial enhancement ratio between stenotic and normally perfused territories was determine

13 to describe the natural history of combined stenotic and regurgitant aortic valve disease.

14 tinely used clinically to assess severity of stenotic and regurgitant valves.

15 ment (AVR) when the aortic valve is severely stenotic and the patient is symptomatic; however, a subs

16 th fusion of the right-left coronary cusp (6 stenotic) and 3 with fusion of the right and noncoronary

17 disease, high-risk plaques (not necessarily stenotic), and overall burden of the disease.

18 ause infarction are not necessarily severely stenotic, and stenotic lesions are not necessarily unsta

19 Small differences in function between stenotic aortic mechanical prostheses, undetectable by c

20 oded CMR as a routine method for quantifying stenotic aortic valve area, to compare this method with

21 y tested the hypothesis that the impact of a stenotic aortic valve depends not only on the cross-sect

22 as used to reconstruct a typical spectrum of stenotic aortic valve geometrics from doming to flat.

23 elated Cc (= continuity/planimeter areas) to stenotic aortic valve shape in 35 patients with high-qua

24 (REpositionable Percutaneous Replacement of Stenotic Aortic Valve Through Implantation of Lotus Valv

25 Operatively excised stenotic aortic valves (with or without associated aorti

26 s of oxidative stress differ greatly between stenotic aortic valves and atherosclerotic arteries.

27 oxidative stress is increased in calcified, stenotic aortic valves and to examine mechanisms that mi

28 ular peak systolic pressure gradients across stenotic aortic valves correlate better with the weights

29 Whereas AVIC from stenotic aortic valves exhibit an augmented response to

30 We examined operatively excised, stenotic aortic valves from 932 patients aged 26 to 91 y

31 stress is increased in calcified regions of stenotic aortic valves from humans.

32 We weighed operatively excised stenotic aortic valves in 324 adults who had undergone p

33 As the weights of the operatively excised stenotic aortic valves increased (from <1 g to >6 g), th

34 hearts not suitable for transplantation and stenotic aortic valves that were removed during surgical

35 correlate the weights of operatively excised stenotic aortic valves to preoperative transvalvular pea

36 us publication has correlated the weights of stenotic aortic valves to the transvalvular gradients or

37 Higher expression of Lp-PLA2 in stenotic aortic valves was confirmed by quantitative pol

38 e interstitial cells and is downregulated in stenotic aortic valves.

39 s a reliable, user-friendly tool to evaluate stenotic aortic valves.

40 nalyze the intrabeat dynamic behavior of the stenotic-aortic valve and compare these measurements wit

41 on catheter selected was advanced across the stenotic area and the IVUS wire advanced in the guide lu

42 The stenotic area measured by PET was 16% smaller than that

43 f hyperemic myocardial blood flow (MBF) in a stenotic area to hyperemic MBF in a normal perfused area

44 on after stenting was equally effective; the stenotic area was reduced (21% versus 65%, P<0.001).

45 At 29 Gy, the histological stenotic area was reduced by 67% (22% versus 66% in cont

46 Flow velocity at anastomoses and suspected stenotic areas was measured.

47 ation that transition from dilated to normal/stenotic arterial calibre coincides with where the inter

48 ardial blood flow in territories supplied by stenotic arteries (1.01+/-0.35 to 0.76+/-0.27 mL.min(-1)

49 uded arteries (77%, 36 of 47) and patent but stenotic arteries (84%, 104 of 124).

50 Implantation of expandable stents into stenotic arteries after percutaneous coronary interventi

51 o FFR-guided PCI had FFR measurements of all stenotic arteries and PCI was done only if FFR was 0.80

52 thoracic aortic dissections to thrombosis in stenotic arteries following plaque rupture, where local

53 of medial SMC hyperplasia and disarray, and stenotic arteries in the vasa vasorum due to medial SMC

54 nal function and maximal perfusion distal to stenotic arteries when administered before the developme

55 At high shear stresses such as are found in stenotic arteries, both steps are mediated by von Willeb

56 r stress, which resembles flow conditions in stenotic arteries, induces significantly more platelet a

57 closely in vivo conditions such as those in stenotic arteries.

58 rams; dephasing was considered severe if the stenotic artery appeared occluded on phase-contrast angi

59 of subsequent stroke in the territory of the stenotic artery is greatest with stenosis > or =70%, aft

60 tio of maximal coronary blood flow through a stenotic artery to the blood flow in the hypothetical ca

61 Risk of stroke in the territory of the stenotic artery was highest with severe stenosis > or =7

62 hest risk for stroke in the territory of the stenotic artery who would be the target group for a subs

63 e in coronary blood flow (CBF) distal to the stenotic artery, resulting in functional improvement of

64 , designed to mimic the flow conditions in a stenotic artery, showed enhanced platelet aggregation in

65 f these strokes were in the territory of the stenotic artery.

66 uent ischemic stroke in the territory of the stenotic artery.

67 Shunts were occluded or severely stenotic at venography and necropsy in the remaining six

68 ly faintly detected in nondiseased tissue or stenotic atheroma.

69 ) cell responses in human AAAs compared with stenotic atheromas.

70 anastomotic collateral networks that augment stenotic bed flow reserve, but at the expense of the adj

71 Explanted, stenotic bicuspid aortic valves (BAVs) from pediatric pa

72 Furthermore, pediatric stenotic bicuspid aortic valves that have lost normal ex

73 platelet-mediated thrombosis in damaged and stenotic canine coronary arteries, due, in large part, t

74 anced vessel patency in remote, damaged, and stenotic carotid arteries, largely due to adenosine rece

75 een in association with TIPS stenoses in all stenotic cases and was not found in 24 of 26 (92%) cases

76 or greater at angiography in 25 of 32 (78%) stenotic cases and was not present in 71 of 72 (99%) cas

77 Intact DSA regularly elicited markedly stenotic CAV in recipients over 28 days.

78 ex vivo pro-fibrotic protein secretion from stenotic CD biopsies.

79 Seven consecutive patients with stenotic CD were studied with UEI and their resected ste

80 In stenotic chambers containing endothelial cells, flow pro

81 ementary in vitro studies using microfluidic stenotic chambers, designed to mimic the flow conditions

82 me and blood flow were markedly lower in the stenotic compared with the contralateral kidney and cort

83 Fifty-five patients with 67 stenotic coronary arteries underwent coronary angiograph

84 ove subsequent vessel patency in damaged and stenotic coronary arteries via release of adenosine from

85 Bypass of stenotic coronary arteries with autologous saphenous vei

86 w conditions comparable to those existing in stenotic coronary arteries.

87 osine, improve vessel patency in damaged and stenotic coronary arteries.

88 d flow, from a region supplied by a severely stenotic coronary artery to those supplied by less disea

89 ffective procedure to reduce the severity of stenotic coronary atherosclerotic disease, its long-term

90 can be characterized as having impaired post-stenotic coronary flow reserve < 2.0 and pressure-derive

91 ased and surgical treatment of significantly stenotic coronary lesions, the comprehensive and serial

92 nsatory enlargement commonly (54%) occurs at stenotic coronary lesions.

93 assessing the coronary circulation and post-stenotic coronary vasodilatory reserve in patients with

94 The measurement of post-stenotic coronary vasodilatory reserve, now possible in

95 atins have little effect in well established stenotic disease with calcification, but their effects e

96 ectomy With Significant Extracranial Carotid Stenotic Disease).

97 involves enhanced, flow-mediated dilation of stenotic epicardial conduit vessels and may account at l

98 n but only superficial erosion of a markedly stenotic, fibrotic plaque.

99 The shortest stenotic fragment was 10 mm long and the longest occlude

100 nts with CMI underwent stent placement in 79 stenotic (>70%) mesenteric arteries.

101 nderwent revision of their nonthrombosed but stenotic HA were reviewed for patient/graft survival, me

102 matory and progrowth changes observed in the stenotic HC+RAS kidney, which might potentially facilita

103 tithrombotic efficacy at denuded or fissured stenotic high-risk lesions without systemic bleeding.

104 Histograms showing the numbers of stenotic ICAs in subgroups and for vessels with stenoses

105 utflow obstruction in 29 percent (1610), and stenotic in 2 percent (92).

106 and inflammatory factors linked to improved stenotic kidney (STK) function after percutaneous transl

107 vascular disease (RVD) amplifies damage in a stenotic kidney by inducing pro-inflammatory mechanisms

108 Stenotic kidney cortical/medullary perfusion and RBF wer

109 usion, low-energy shockwave therapy improves stenotic kidney function, likely in part by mechanotrans

110 reduces renal blood flow (RBF) and amplifies stenotic kidney hypoxia.

111 Recovery of the stenotic kidney in RVD after ELP-VEGF therapy may be dri

112 Pigs then received a single stenotic kidney infusion of ELP-VEGF (100 mug/kg), a mat

113 high renal binding of ELP-VEGF 4 hours after stenotic kidney infusion.

114 nuated renovascular hypertension, normalized stenotic kidney microvascular density and oxygenation, s

115 n rate (GFR) were similarly decreased in the stenotic kidney of both RVD groups.

116 Stenotic kidney RBF rose (202+/-29-262+/-115 mL/min; P=0

117 remodeling, and improved IMV function in the stenotic kidney, independent of lipid lowering.

118 In the stenotic kidney, intratubular contrast content has decre

119 In the stenotic kidney, the hemodynamic impairment of the corte

120 Results In the stenotic kidney, the median magnetization transfer ratio

121 effects on the function and structure of the stenotic kidney.

122 icrovascular density, and oxygenation in the stenotic kidney.

123 fer, fractional kidney hypoxia was higher in stenotic kidneys compared with kidneys with EH (17.4% vs

124 To determine the application of imaging the stenotic lacrimal punctum with infrared photographs and

125 In the stenotic LAD zone, MBF did not change significantly.

126 served in the asynergic zone perfused by the stenotic LAD.

127 Human AVIC were isolated from normal and stenotic leaflets.

128 resorbable scaffold implantation in a simple stenotic lesion resulted in stable lumen dimensions and

129 om a stroke), probably culprit (not the most stenotic lesion upstream from a stroke), or nonculprit (

130 assified as either culprit (the only or most stenotic lesion upstream from a stroke), probably culpri

131 e requiring angioplasty of a progressive FMD stenotic lesion.

132 n of the total myocardium in jeopardy from a stenotic lesion.

133 significantly higher in nonstenotic than in stenotic lesions (1.3 +/- 0.2 vs. 1.0 +/- 0.2, p < 0.001

134 icantly different between nonstenotic versus stenotic lesions (20 +/- 8 mm(2), n = 23 vs. 22 +/- 8 mm

135 gration, a key feature in the development of stenotic lesions after balloon injury.

136 n are not necessarily severely stenotic, and stenotic lesions are not necessarily unstable.

137 We have shown that cells derived from stenotic lesions in infrainguinal vein grafts were signi

138 tion (PCI) should be considered for severely stenotic lesions in proximal coronaries that subtend a l

139 Human vein graft-threatening stenotic lesions were identified by duplex scanning with

140 The location and severity of stenotic lesions were recorded.

141 n of the first balloon-expandable valves for stenotic lesions with implantation in the pulmonic posit

142 In five stenotic lesions, "negative remodeling" (Remodeling Inde

143 Notably, stenotic lesions, but not AAAs, contained mature forms o

144 ow often early arterial wall changes lead to stenotic lesions, use of these modalities in combination

145 IL-2 and IL-15, which are amply expressed in stenotic lesions.

146 une responses appear to predominate in human stenotic lesions.

147 as sudden (abrupt appearance of a normal or stenotic low-resistance signal), stepwise (flow improvem

148 ater, and the intima/medial ratio as well as stenotic luminal area was more pronounced in apoE(-/-) m

149 The developed stenotic microfluidic chamber offers a realistic platfor

150 Of the 31 occluded (n = 8) and stenotic (n = 23) shunts, ultrasonography accurately pre

151 By imaging, defect magnitude (stenotic/normal) was greater for (201)Tl than MIBI (0.57

152 Stenotic/obstructed IFV and IVC may be reconstructed usi

153 fety and efficacy of stent reconstruction of stenotic/occluded iliofemoral veins (IFV) and inferior v

154 One or both ICAs were stenotic on all patient MR arteriograms.

155 and/or management of coronary calcification, stenotic or obstructive disease, high-risk plaques (not

156 Patients with congenital heart defects and stenotic or occluded IFV/IVC may encounter femoral venou

157 n staging, i.e., early atheroma versus later stenotic or occlusive atherothrombosis.

158 ervention is dependent on the anatomy of the stenotic or occlusive lesion; percutaneous interventions

159 se due to de novo superficial femoral artery stenotic or occlusive lesions were randomized to treatme

160 saturation, should not be misinterpreted as stenotic or occlusive vascular disease.

161 mineralization remains the leading cause of stenotic or regurgitant failure in native human and porc

162 Surgical treatment of stenotic or regurgitant valvular lesions can alter the n

163 ree-dimensional axisymmetric models of round stenotic orifices were created.

164 showed enhanced platelet aggregation in the stenotic outlet region at 60-80% channel occlusion over

165 d increased endothelial vWF secretion in the stenotic outlet region, contributing to exacerbated plat

166 ncreased platelet aggregate formation in the stenotic outlet region.

167 Because severely stenotic plaques are more likely to stimulate collateral

168 Vascular disease can manifest as stenotic plaques or ectatic aneurysms, although the mech

169 oliferation identified in recurrent coronary stenotic plaques.

170 oronary events arise from ruptures of mildly stenotic plaques.

171 f iFR was similar to resting Pd/Pa and trans-stenotic pressure gradient and significantly inferior to

172 , or according to the magnitude of the trans-stenotic pressure gradient.

173 lar function, number of diseased vessels, or stenotic proximal left anterior descending artery.

174 lar function, number of diseased vessels, or stenotic proximal left anterior descending artery.

175 Balloon dilation of the stenotic pulmonary veins was performed in these patients

176 alloons readily increase the diameter of the stenotic pylorus on average from 6 to 16 mm.

177 n rate (GFR) were decreased similarly in the stenotic RAS and HC+RAS kidneys, but tubular fluid reabs

178 Stenotic RBF was reduced compared with RBF of contralate

179 aximal adenosine stress, MR clearly depicted stenotic regions and showed regional signal differences

180 que rupture, complex pulsatile flows through stenotic regions producing high wall shear stresses, and

181 We assessed BP, urinary protein, stenotic renal blood flow, GFR, microvascular structure,

182 pe (WT) mouse (control) undergoes a dramatic stenotic response, which is nearly completely abolished

183 Stents provide effective treatment for stenotic saphenous venous aorto-coronary bypass grafts,

184 Short-term lipid-lowering therapy increases stenotic segment maximal myocardial blood flow by approx

185 significantly higher than those in the post-stenotic segment of the diseased artery (1.8 +/- 0.6, p

186 Treatment methods included resection of the stenotic segment with primary reanastomosis (n = 17), ao

187 stimulate collateral circulation to the post-stenotic segment, plaque rupture and thrombosis at such

188 maging confirmed balloon location within the stenotic segment.

189 Out of 45 stenotic segments, 29 were single stenotic segments (16 intracranial and 13 extracranial)

190 al and 13 extracranial) and 16 were multiple stenotic segments (8 intracranial and 8 extracranial).

191 In the total number of stenotic segments (single and multiple), there were 24 (

192 largement or vessel constriction occurred in stenotic segments compared with the reference segments a

193 r significant stenosis and a total number of stenotic segments was 45.

194 Seven (18%) of 38 significantly stenotic segments were classified as having < 50% stenos

195 Out of 45 stenotic segments, 29 were single stenotic segments (16

196 only 9 (29%) of the 31 correctly classified stenotic segments, were severely calcified (area > 20 mm

197 Noninvasive assessment of functionally stenotic small-diameter aortic mechanical prostheses is

198 There was no difference between stenotic stents and nonstenosed stents with respect to c

199 However, smooth muscle cells (SMC) from stenotic stents demonstrated both greater cell prolifera

200 oliferative activity in tissues excised from stenotic stents has not been previously reported.

201 ant (accounting for 99% of the total drop in stenotic subjects).

202 enoses, new evidence suggests that opening a stenotic subsidiary branch may create unfavorable hemody

203 patient underwent balloon angioplasty of the stenotic SVC segment with resolution of her bleeding and

204 ive in diagnosing occluded and significantly stenotic tibial artery disease in these patients compare

205 tive in diagnosing occluded or significantly stenotic tibial artery disease.

206 During dobutamine stress, the stenotic-to-normal (99m)Tc-N-NOET activity ratio was 0.6

207 During adenosine stress, the stenotic-to-normal activity ratio for (99m)Tc-N-NOET was

208 The stenotic-to-normal flow ratio was 0.33+/-0.04 at the tim

209 The stenotic-to-normal flow ratio was 0.47+/-0.04 at the tim

210 In dogs with reduced flow reserve, the stenotic-to-normal sestamibi activity ratio (0.86+/-0.03

211 In protocol 1, 2-hour NOET and 201Tl stenotic-to-normal tissue activity ratios were similar (

212 Explanted stenotic tricuspid aortic valves were weighed, and fibro

213 nd corresponding blood damage index (BDI) in stenotic turbulent blood flow.

214 examination of the resected gall bladder and stenotic ureteric segment showed CMV inclusions, confirm

215 strong relevance to clinical measurements of stenotic valve areas by use of the Doppler continuity eq

216 example, the hypothesis that the impact of a stenotic valve depends not only on its limiting orifice

217 AVICs isolated from stenotic valves had greater expression of TLR2 and TLR4

218 Stenotic valves opened and closed more slowly than norma

219 Superoxide levels in stenotic valves were significantly reduced by inhibition

220 In stenotic valves, superoxide levels were increased 2-fold

221 ensional (2D) measurements decreased in less stenotic valves.

222 w was shorter than valve opening in severely stenotic valves.

223 fferences between the dynamics of normal and stenotic valves.

224 augmentation of the TLR4 response in AVIC of stenotic valves.

225 ponse to lipopolysaccharide (LPS) in AVIC of stenotic valves.

226 ty was not increased in calcified regions of stenotic valves.

227 so markedly elevated in calcified regions of stenotic valves.

228 ease is the primary cause of regurgitant and stenotic valvular lesion in the U.S.

229 in the medial layer (68% of PCNA + cells) of stenotic vein grafts.

230 distal protection device during stenting of stenotic venous grafts was associated with a highly sign

231 on thickening of endothelial cell layer and stenotic versus nonstenotic medial wall thickening.

232 al versus subintimal crossing, location, and stenotic versus occlusive disease.

233 therapeutic combination for the treatment of stenotic vessel disease.

234 roke and stroke in the same territory of the stenotic vessel was compared in patients grouped by mean

235 ic stroke and stroke in the territory of the stenotic vessel.

236 Stenotic vessels were dilated by using 5-6-mm-diameter b

237 gh guide wires were easily passed across the stenotic vessels, occluded vessels required puncture thr

238 ate, however--even in patients with severely stenotic vessels--is relatively low, which suggests that

239 ease systolic thickening was observed in the stenotic zone (2.7+/-0.4 versus 4.6+/-0.3 mm in the norm

240 Stenotic zone flow and thickening did not increase durin

241 After stress, stenotic-zone blood flow and oxygen consumption were red

242 In group 2, stenotic-zone contraction with stress declined versus ba

243 Baseline stenotic-zone endocardial blood flow was reduced versus

244 Stenotic-zone endocardial flow was unchanged versus base

245 Stenotic-zone thickening increased at low but not at hig

246 Finally, a significant reduction in stenotic-zone thickening was seen during postdobutamine