ライフサイエンスコーパス: step reaction

1 ep, rather than the previously described two-step reaction.

2 t the second (rearrangement) step of the two-step reaction.

3 t plasminogen is converted to AS4.5 in a two-step reaction.

4 t this mode of chromatin remodeling is a two-step reaction.

5 analog was prepared similarly, but in a two step reaction.

6 reduced to 1-hexadecanol by LiAlH4 in a one-step reaction.

7 ase A2 and were synthesized in a one-pot two-step reaction.

8 to reversible self-cleavage but was a three-step reaction.

9 ing a one-pot hydrothermal method via single-step reaction.

10 in contrast to DB-JBP1, which binds in a one-step reaction.

11 sized in high yields on gram scales in a one-step reaction.

12 Binding of gHgL to integrins is a two-step reaction.

13 entrance and the heme group during the three-step reaction.

14 the transformation of AA to LTA(4) in a two-step reaction.

15 erted into the substrate via a consecutive 2-step reaction.

16 -Cryp) was successfully synthesized by a one-step reaction.

17 es the formation of NO via a consecutive two-step reaction.

18 activation of acetate to acetyl-CoA in a two-step reaction.

19 2).(diamine)] can be synthesized in a single-step reaction.

20 difficult, particularly in complicated multi-step reactions.

21 location as a sequence of coupled hydrolysis-stepping reactions.

22 Using a one-step reaction, a bifunctional compound was synthesized f

23 The one-pot, two-step reaction also worked with electron-rich hydroxy- an

24 peak, is easily synthesized via a simple one-step reaction and is formulated in water with high stabi

25 ycloisomerization becomes a complex multiple-step reaction and proceeds with a rate-determining barri

26 ins can be more complex than a simple single-step reaction, and that application of several methods c

27 hereas the discrimination in the overall two-step reaction arises from very weak binding of noncognat

28 were obtained in quantitative yield in a one-step reaction at ambient temperature from the commercial

29 DnaK-peptide complexes according to the two-step reaction, ATP + DnaK-P if ATP-DnaK-P if ATP-DnaK +

30 f the reaction course indicate a virtual one-step reaction between the NHC and the silanorbornadiene.

31 Protein splicing proceeds through a four-step reaction but the catalytic mechanism is not fully u

32 ediators formed from arachidonic acid in a 2-step reaction catalyzed by 5-lipoxygenase (5-LOX) requir

33 rom soluble Mn(II) to Mn(IV) oxides is a two-step reaction catalyzed by an MCO-containing complex.

34 reaction is a "simple" extension of the two-step reaction catalyzed by MR: base-catalyzed proton abs

35 , indicating that ester production was a two-step reaction consisting of hydrolysis and esterificatio

36 -chlorobenzoyl-coenzyme A formation in a two-step reaction consisting of the adenylation of 4-chlorob

37 red reaction pathway, compared to the single-step reaction, constitute the key advantages of this tan

38 In this two-step reaction, first-strand scission is mediated by a nu

39 the behavior of KIEobs for a reversible two-step reaction for all possible values of the rate consta

40 In this Communication, we describe a two-step reaction for preparing three-dimensional electrodes

41 strate availability, we also developed a two-step reaction for the enzymatic synthesis of UDP-l-rhamn

42 Under a new approach, we developed a one step reaction for the interconversion of artemisinin 1 i

43 g intermediate participates in normal second-step reactions, forming spliced exon and linear intron R

44 ing deterrent that can be formed in a single step reaction from 3-dehydroquinate catalyzed by quinate

45 The combined two step reaction gave a radiochemical yield of 10-15% (EOB)

46 The overall four-step reaction gave higher yields (57%) than the two-step

47 gens to estrogens through a sequential three-step reaction, generating 19-hydroxy and 19-aldehyde int

48 A mechanism is proposed for the two-step reaction governed by the synthetase, in which His41

49 PASP-IO nanoparticles made by single-step reaction have a core size of 5 nm with a hydrodynam

50 70 complex rapidly binds hsp90 in the second step reaction in a nucleotide-independent manner.

51 of highly sulfated keratan sulfate by a two-step reaction in vitro with a mixture of beta3GnT7/beta4

52 ts in tyrosine nitration, catalyzed as a two-step reaction in which nitric-oxide synthase induction i

53 alysis of PCNA opening by RFC revealed a two-step reaction in which RFC binds PCNA before opening PCN

54 This is a two-step reaction in which the enzyme first condenses with G

55 Formation of pyruvate by SDH is a two-step reaction in which the hydroxyl group of serine is c

56 halose biosynthesis in plants involves a two-step reaction in which trehalose-6-phosphate (T6P) is sy

57 onine S-adenosyltransferase) catalyzes a two-step reaction in which tripolyphosphate (PPPi) is a tigh

58 ediate species in total, we map out relevant step reactions in a model size growth reaction from mole

59 synthetic history-that is, a complete set of step reactions in their synthetic routes.

60 h seven 1,3,5-triazines was studied in a one-step reaction (in situ formation of 3-aminopyrrole) and

61 BP1 binds to J-DNA or glu-5-hmC-DNA in a two-step reaction, in contrast to DB-JBP1, which binds in a

62 f class II synthetases and carries out a two-step reaction, in which lysine is activated by being att

63 xperiments and computations indicate a three-step reaction including isomerization of diazomethane, a

64 tic resonance spectroscopy, with temperature-step reaction initiation, starting from the enzyme-coenz

65 ring progress of the decay after temperature step reaction initiation.

66 sor messenger RNA (pre-mRNA) splicing, a two-step reaction involved in a multitude of RNA structural

67 ab' fragments was also consistent with a two-step reaction involving fast high-affinity binding and a

68 s the addition of water to epoxides in a two-step reaction involving initial attack of an active site

69 slational modification is performed in a two-step reaction involving the addition of a beta-lysine mo

70 midation of bioactive peptides through a two-step reaction involving the monooxygenase and lyase doma

71 presence of both catalyst and solvent, a two-step reaction is predicted, corresponding to the stepwis

72 hase (NOS) generates NO via a sequential two-step reaction [l-arginine (l-Arg) --> N-hydroxy-l-argini

73 The elementary step reaction mechanism derived from this comprehensive

74 ld and made it possible to demonstrate a two-step reaction mechanism for des-PPW with K init = 10.4 +

75 The data support the proposed four-step reaction mechanism of ACDs, coupling acyl-CoA thioe

76 This two-step reaction mechanism of the widely used Amplex Red, a

77 A five-step reaction mechanism was used to account for the obse

78 inds single-headed myosin VI following a two-step reaction mechanism with formation of a low affinity

79 er the entire temperature range with a three-step reaction mechanism, originally proposed by Ashton e

80 However, kinetic modeling indicated a two-step reaction mechanism, with formation of peroxocarbona

81 sociation of a protein complex follows a two step reaction mechanism, with the first step being the f

82 aBH(4)-sensitive intermediate suggests a two-step reaction mechanism.

83 ng atomic resolution images) reveals a three-step reaction mechanism.

84 nick, is the rate-limiting step in the multi-step reaction mediated by hNTH1.

85 cient alternative pathway in which the first-step reaction occurs by hydrolysis.

86 spliceosomal and group II introns, the first-step reaction occurs by nucleophilic attack on the 5' sp

87 0 Da poly(propylene fumarate) (PPF) by a two-step reaction of diethyl fumarate and propylene glycol t

88 substituents are synthesized by using a one-step reaction of H(8)BINOL with amino methanols that wer

89 e DFT-level mechanism elucidation of the two-step reaction of non-heteroatom-stabilized carbenes with

90 The one-step reaction of some amino-substituted heterocycles wit

91 One-pot three-step reactions of 50, 51, and 56 provided the desired 3'

92 Resolution of the two-step reactions of AT and AT-Denver with wild-type and mu

93 Resolution of the two-step reactions of AT with the mutant thrombins revealed

94 In the next step, reaction of the sugar-derived (Z)-1-bromo-1-nitroa

95 athway comprising three nucleotidyl transfer steps: reaction of Rtc with ATP to form a covalent Rtc-(

96 d carbon dioxide can be produced in a single-step reaction over the catalyst, with no detectable CO (

97 s of ghrelin follows an unprecedented single-step reaction pathway and the single-step acylation proc

98 The single-step reaction pathway for the acylation is remarkably di

99 Mechanistic studies support a two-step reaction pathway involving initial dissociation of

100 s the first time demonstrating that a single-step reaction pathway is possible for an ester hydrolysi

101 tions provide evidence for an unexpected two-step reaction pathway, which involves dehydrogenative in

102 ation process must follow the well-known two-step reaction pathway.

103 ed by changes in the first on rates of a two-step reaction pathway.

104 oselectivity differences thus enabled single-step reaction pathways to an effective collection of dox

105 The two-step reaction progress also was monitored in real time b

106 proteins at cysteine residues, but this two-step reaction requires lengthy incubations and produces

107 The proposed derivatization is a one-step reaction, requires no organic solvents, and is safe

108 Polyadenylation of mRNA precursors is a two-step reaction requiring multiple protein factors.

109 midating monooxygenase (PAM) catalyzes a two-step reaction resulting in the C-terminal amidation of p

110 Kinetic studies of the two-step reaction revealed that the variants show a signific

111 en-1-yl phosphonates were prepared in a five-step reaction route from beta-ketophosphonates.

112 These observations favor a two-step reaction scheme involving two complete oxidative cy

113 e other as the emitter electrode, a multiple-step reaction scheme was achieved that included consecut

114 A three-step reaction sequence has been developed to prepare a v

115 izidine 5,8-epi-indolizidine 223A via a five-step reaction sequence in 32% overall yield.

116 Here we demonstrate a three-step reaction sequence in which a copper complex convert

117 fold diversity has been achieved using a two-step reaction sequence involving allylic substitution an

118 -R species, where R = H or -CH3, using a two-step reaction sequence involving chlorination of H-Si(11

119 here carbamyl phosphate is formed in a three-step reaction sequence.

120 ined in a 6.7% overall yield following an 11-step reaction sequence.

121 ne in good to excellent yields using a three-step reaction sequence.

122 n of 10 to 1 is accomplished through a three-step reaction sequence.

123 NO from L-arginine, NADPH, and O(2) in a two-step reaction sequence.

124 orts to design selective catalysts for multi-step reactions, such as hydrodeoxygenation (HDO), have e

125 -Hydroxybenzoate hydroxylase catalyzes a two-step reaction that demands precise control of solvent ac

126 on a large scale, in high yield using a one-step reaction that employs commercially available reagen

127 Beetle luciferases catalyze a two-step reaction that includes the initial adenylation of t

128 protein synthase III (FabH) catalyzes a two step reaction that initiates the pathway of fatty acid b

129 osphatidylinositol 4,5 bisphosphate in a two step reaction that involves a cyclic intermediate.

130 enzymes catalyze mechanistically similar two-step reactions that proceed through an enzyme-bound acyl

131 In the two-step reaction, the activated intermediate, bio-5'-AMP, i

132 In a fast, single-step reaction, the monomeric alkoxide precursors permeat

133 imetric analysis results, which show the two-step reaction to be exothermic by -215 kJ mol(-1), in ag

134 A two-step reaction to convert terminal alkynes into triboryla

135 orming family of enzymes that catalyze a two-step reaction to first activate a carboxylate substrate

136 ch using LCA as a template, along with a two-step reaction to generate sodium 3-hydroxyolean-12-en-30

137 5-lipoxygenase (5-LO), which catalyzes a two-step reaction to produce leukotriene A4.

138 mines (-NH2), and this allowed for the multi-step reactions to be carried out in tandem within the MO

139 ated actin filaments in an apparently single step reaction upon binding, whereas the stabilization by

140 oups of hyaluronan are biotinylated in a one-step reaction using biotin-hydrazide.

141 ocked by stoichiometric acetylation in a one-step reaction using sulfosuccinimidyl acetate (S-NHSAc)

142 situ formation of 3-aminopyrrole) and a two-step reaction (using the tetraphenylborate salt and an a

143 dic acid is typically synthesized in a three-step reaction utilizing three enzymes: glycerol 3-phosph

144 ntibodies within minutes in a homogenous one-step reaction visible to the naked eye.

145 te kinetics applicable to realistic multiple step reactions, we present here the successful applicati

146 Concerted and two-step reactions were designed to evaluate (+) strand prim

147 batteries, whose lithiation undergoes a two-step reaction, whereby intercalation and conversion occu

148 hibitor was shown to bind thrombin via a two-step reaction wherein the initially formed thrombin-inhi

149 MAT catalyzes the two-step reaction which synthesizes S-adenosylmethionine (Ad

150 0 kDa) proteins was accomplished in a single-step reaction with a commercially available bis(2,2'-bip

151 ry in optically pure form using a simple one-step reaction with commercially available reagents.

152 They can be additionally modified in a one-step reaction with functional groups for covalent labeli

153 activation of the E. coli enzyme is a single-step reaction with kon = 1.94 x 10(4) M-1 s-1.

154 ther spliceosomal components, performs a two-step reaction with two short RNA oligonucleotides as sub

155 s of complexes 1 and 2 are classified as two-step reactions with an element of reversibility.

156 es RNA 2',3' cyclic phosphate ends via three steps: reaction with ATP to form a covalent RtcA-(histid

157 oth DNA substrates occurs by a minimum three-step reaction, with the bimolecular step followed by two

158 coccus triterpene synthases, catalyzes a two-step reaction within a single enzyme unit without interm