ライフサイエンスコーパス: steppe

1 and then Bronze Age herders from the Pontic Steppe.

2 Caragana is of arid origin from the Junggar steppe.

3 the primary land use in the Hulunber meadow steppe.

4 in eastern and western parts of the Eurasian Steppe.

5 likely from northern Eurasia and the Pontic Steppe.

6 o so efficiently on either meadows or desert-steppes.

7 e restoration of degraded steppes and desert-steppes.

8 minus end-directed to net plus end-directed stepping.

9 from minus end-directed to plus end-directed stepping.

10 xplain the accelerated triggering of induced stepping.

11 al ladder, a complex task requiring accurate stepping.

12 their involvement in control of accuracy of stepping.

13 I4 depolarization never elicited stepping.

14 es of inability to produce effective forward stepping.

15 e motor head binds to the microtubule during stepping.

16 fundamentally from that of plus-end-directed stepping.

17 one- (1.(H2O,EtOH)), two- (1.3H2O) and three-stepped (1.

18 y of macrocycle conformations ranging from a stepped 2 + 2 macrocycle to a multiply folded 8 + 8 macr

19 For voluntary stepping, a disruption in the normal coupling between po

20 echanism and coordination of KIF3A and KIF3B stepping, a presteady-state kinetic analysis was pursued

21 s showed significant improvement in hindlimb stepping ability, quadrupedal weight support, and all me

22 During induced stepping, accelerated step initiation may represent an e

23 t least two varieties of carbonates, using a stepped acid dissolution technique paired with ion micro

24 We propose that the minus end-directed stepping action of Cut7 is selectively inhibited by coll

25 r neighbors inhibit their minus end-directed stepping action, but not their plus end-directed steppin

26 ping action, but not their plus end-directed stepping action.

27 ental data from GFP-labeled kinesin-1 motors stepping along immobilized microtubules, we show 1) that

28 mer 'gate' each other to promote coordinated stepping along microtubules.

29 e the ability to switch protofilaments while stepping along the microtubule when challenged by an obs

30 ve functions are linked to delayed voluntary stepping, alterations in the coupling of posture and loc

31 ons in the northern UK have higher levels of Steppe ancestry and that UK population structure cannot

32 the arrival of new people with predominantly Steppe ancestry but whose ancestors had undergone sex-sp

33 This steppe ancestry persisted in all sampled central Europea

34 widespread decline of vegetation across the steppe and about 70% of this ecosystem is now considered

35 opical rainforest, alpine regions worldwide, steppe and prairie regions of central Asia and North and

36 framework can also undergo a combination of stepped and continuous breathing.

37 eratures limited the restoration of degraded steppes and desert-steppes.

38 errors in the parametric control of induced stepping and its effectiveness in stabilizing balance wo

39 s dual functionality, with microtubule-based stepping and regulation of microtubule dynamics.

40 he rhythmic output required for coordinating stepping and stabilizing the body axis during movements.

41 he rhythmic output required for coordinating stepping and stabilizing the body axis during movements.

42 ium in meadows, a non-linear increase across steppes, and an abrupt impulse in desert-steppes followi

43 o treatment strategies are currently used, a stepped approach beginning with more simple care that is

44 A new hybrid time stepping approach, which couples the Runge-Kutta and New

45 if precipitation increases in the temperate steppe as predicted under future climate-change scenario

46 er separation of the East-European and Asian steppes as well as European 'warm-stage' refuges.

47 In this population-based fMRI study, we stepped back by over a decade to characterize the change

48 Pase rate, microtubule-binding affinity, and stepping behavior of dynein, and that microtubule bindin

49 -molecule microscopy to directly observe the stepping behavior of kinesin-1 and -2 family motors with

50 e consistent with a model wherein the normal stepping behavior of the myosin is supplemented by the p

51 standing dynein's directionality and unusual stepping behaviour.

52 product of hybridization between the extinct steppe bison (Bison priscus) and ancestors of modern cat

53 nt have alternated ecological dominance with steppe bison in association with major environmental shi

54 son fossil in North America, a 130,000-y-old steppe bison, Bison cf. priscus We extracted and sequenc

55 genomic influence concordant with introduced Steppe burial rites.

56 fully enhanced the NDVI on the most degraded steppes, but did not do so efficiently on either meadows

57 Here, we examined how base triplet stepping by RecA, Rad51, and Dmc1 is affected by DNA seq

58 at ATP hydrolysis in the bound head precedes stepping by the tethered head, leading to a mechanochemi

59 Bronze Age migration from the Pontic-Caspian Steppe, can be investigated using patterns of genetic va

60 n a deeper understanding of long-term forest-steppe carbon dynamics, we use a highly resolved, multip

61 Purpose A stepped care (SC) program in which an effective yet leas

62 of a stepped care case-finding intervention (stepped care [SC]) vs a moderate-strength single-level i

63 symptom monitoring with an algorithm-guided stepped care approach to optimizing analgesics.

64 To simulate a comparison of a stepped care case-finding intervention (stepped care [SC

65 Stepped care is an increasingly popular treatment model

66 In conclusion, stepped care model appeared to be better than CAU in tre

67 r "low-intensity" interventions as part of a stepped care model.

68 included in this review, of which 6 examined stepped care prevention and 4 examined stepped care trea

69 mpare the efficacy and cost-effectiveness of stepped care prevention and treatment with care-as-usual

70 No significant difference was found between stepped care prevention/treatment and CAU in preventing

71 Results showed stepped care treatment revealed a significantly better p

72 nxiety disorders was significantly higher in stepped care treatment than in CAU.

73 mined stepped care prevention and 4 examined stepped care treatment, specifically including ones rega

74 Stepped care was associated with greater reach and was s

75 decrease in blood pressure than standardized stepped-care antihypertensive treatment alone.

76 of renal denervation added to a standardized stepped-care antihypertensive treatment for resistant hy

77 eatment, renal denervation plus standardized stepped-care antihypertensive treatment resulted in a gr

78 igned to renal denervation plus standardized stepped-care antihypertensive treatment, or the same ant

79 For standardized stepped-care antihypertensive treatment, spironolactone

80 n implemented through collaborative care and stepped-care approaches.

81 h community-based workers in a collaborative stepped-care framework is an approach that is ripe to be

82 Physicians should consider a stepped-care model in which patients may begin with rela

83 We find that this trait underwent stepped change, from thick to semi-thin to thin seed coa

84 nt from 2014 to 2016 in the eastern Eurasian steppe, China.

85 Stepped collaborative care intervention included motivat

86 a long-lived life stage and (2) a sagebrush steppe community IPM.

87 ge Scythian culture spread over the Eurasian Steppe, covering a territory of more than 3,500 km in br

88 ics of structural transitions underlying the stepping cycle of kinesin-1 at physiological ATP, we use

89 rimental grounds, the repercussions of their stepping cycle on the collective dynamics still remains

90 aturating ATP, kinesin-1 spends half of each stepping cycle with one head bound, specifying a structu

91 the energy requirements for the fundamental stepping cycle, which likely includes energy from glycos

92 that trigger the two key transitions in the stepping cycle: detachment of the trailing head from the

93 The stepped decline is argued to reflect marine downdraw tri

94 ter delta(13)CDIC, the last of a longer-term stepped decrease through the Spathian.

95 to individual motor domains in processively stepping dimers.

96 for full-length Cut7, the key determinant of stepping direction is the degree of motor crowding on th

97 yeast kinesin-5 motors, Cut7 can reverse its stepping direction, by mechanisms that are currently unc

98 s presented show that the kinesin processive stepping distance decreases 40-60% with EC50 values <100

99 col at a lower total dose (0.5-5.0 mSv, with stepped doses of 0.5 mSv).

100 89.4% (95% CI, 86.4% to 92.4%) of those who stepped down had preserved asthma control compared with

101 Eligibility for stepping down asthma controller medications included no

102 We sought to compare the safety and costs of stepping down asthma controller medications with maintai

103 Limited data exist regarding outcomes after stepping down asthma medication.

104 Stepping down asthma medications in those whose symptoms

105 95% or more of the Cyt c population folds by stepping down through the same set of foldon-dependent p

106 with the other factors to reduce chances of stepping down, but did not constitute a problem factor w

107 ows due to lower temperatures and for desert-steppes due to limitations caused by the small species p

108 semi-nomadic people that ruled the Eurasian steppe during much of the first millennium BCE.

109 For later migrations from the Pontic Steppe during the late Neolithic/Bronze Age, however, we

110 Forest-steppe dynamics were reconstructed using pollen, and dia

111 germane to the findings of our Report: that stepping dynamics provided a better statistical descript

112 e-trial analysis of licking behavior reveals stepping dynamics with variable onset times, which is re

113 ous diffusion-to-bound dynamics or discrete "stepping" dynamics.

114 ant functional group removal experiment in a steppe ecosystem in Inner Mongolia, China, and quantifie

115 can change collaboratively in this semiarid steppe ecosystem.

116 The forest-steppe ecotone in southern Siberia is highly sensitive t

117 tral and peripheral stalks affects c-subunit stepping efficiency.

118 ir autosomes with European hunter-gatherers, Steppe Eneolithic and Bronze Age populations, and Europe

119 st product dissociation, and that isoprenoid stepping ensures short transit times.

120 nd wild sheep (mouflon), characteristic of a steppe environment.

121 , absolute bias of 0.54% to the standardized stepped field (DT)CCSN2 values on the reference system.

122 The traditional stepped field CCS method performs with a relative standa

123 ons of this analysis include molecular-motor stepping, fluorophore bleaching, electrophysiology, part

124 oss steppes, and an abrupt impulse in desert-steppes following a slight increase in productivity.

125 5-853 kcal/day formula diet for 3-5 months), stepped food reintroduction (2-8 weeks), and structured

126 rvation of enzymatic memory in translocation stepping, for the kinetics of translocation steps of dif

127 ich allows us to identify admixture into the steppe from at least two external sources.

128 me liposome-based drug products have already stepped from the lab-bench to the market.

129 coverage (10.5x) genome, showed substantial Steppe genetic heritage indicating that the European pop

130 l in response to continuous sheep grazing in steppe grasslands.

131 graphical distributions of the aphid and its steppe habitat.

132 eir predecessors, but in Russia, the Yamnaya steppe herders of this time were descended not only from

133 mes significantly contributed to the Yamnaya steppe herders who migrated into Europe approximately 3,

134 age, where {100} facets roughen into vicinal stepped high Miller index facets, while {111} facets rem

135 l glucose reabsorption was measured with the stepped hyperglycemic clamp in 15 subjects with type 2 d

136 placebo-controlled cross-over trial using a stepped hyperinsulinemic hypoglycemia clamp was performe

137 ter intrahepatic islet transplantation using stepped hyperinsulinemic-hypoglycemic and paired hyperin

138 On day 2, subjects underwent stepped hypoglycemic clamps (nadir 60 mg/dL) with evalua

139 Our results showed that the semi-arid steppe in north China was resistant to both daytime and

140 ation) were explored in a semiarid temperate steppe in northern China.

141 ing on the temporal stability of a temperate steppe in northern China.

142 ng season on soil respiration in a temperate steppe in the Mongolian Plateau.

143 p. przewalskii) were discovered in the Asian steppes in the 1870s and represent the last remaining tr

144 zed into a hierarchy that precisely controls stepping in a stereotypic, speed-dependent fashion.

145 evocation of spontaneous and actively driven stepping, including optimization of these behaviors in d

146 ation of artificial nanofluidic devices have stepped into a completely new stage, termed 2D nanofluid

147 The Mongolian Steppe is one of the largest remaining grassland ecosyst

148 During imbalance, stepping is a powerful protective action for preserving

149 g and falls, initiation slowing of voluntary stepping is observed together with perturbation-induced

150 epresent an event-triggering process whereby stepping is released according to the occurrence of a pe

151 rference (i.e., load-dependent modulation of stepping kinetics and binding-site exclusion), whereas f

152 Analysis of stepping kinetics in varying nucleotides shows that ATP

153 gs are consistent with recent studies of the stepping kinetics of the motor.

154 The randomness of stepping leads to a buildup of tension in the linkage be

155 clinical decision making that involves four stepped levels, proceeding from the lowest to the highes

156 We examined the ability to generate stepping-like movements in response to ES and/or IS of s

157 relimb movements appeared first, followed by stepping-like movements in the hindlimbs.

158 examine the structural dynamics of dynein's stepping mechanism in real time, we used polarized total

159 her, these observations demonstrate that the stepping mechanism of dynein is fundamentally different

160 many of the critical unknown aspects of the stepping mechanism of myosin 5 including head-head coord

161 f dynein is fundamentally different from the stepping mechanisms of other well-studied MT motors, bec

162 n transitions dynamically between the active stepping mode and this weak surface-associated mode enha

163 e window of evidence accumulation, and their stepping model cannot explain existing data as effective

164 ons we recorded were better described by the stepping model.

165 marine N cycle using a multicompartment time-stepping model.

166 Toward this end, single-molecule, in vitro stepping-motility assays are commonly used to determine

167 for the estimation of motility parameters in stepping-motility assays.

168 ular tension sensing is observed in dynein's stepping motion at high interhead separations.

169 he geometry, we propose a diffusive sideward stepping motion of Kip3 on the microtubule lattice, asym

170 synthase (FOF1) is comprised of two rotary, stepping motors (FO and F1) coupled by an elastic power

171 ighttime warming experiment in the temperate steppe of north China with a natural drought event durin

172 s (twice year(-1) or monthly) in a temperate steppe of northern China across 2008-2013, we found that

173 their effects on ECE in a semiarid temperate steppe of northern China for three consecutive years wit

174 seasons (2010-2012) in a semiarid temperate steppe of Northern China.

175 raging exclusion experiment in the sagebrush steppe of the North American Rocky Mountains, combining

176 synthase, and explain the need for the finer stepping of the F1 motor in the mammalian system, as see

177 ing of how ATP binding is coupled to forward stepping of the motor.

178 vity during more automated behavior, such as stepping on a treadmill.

179 the walker's center-of-mass will facilitate stepping on target footholds.

180 ses ATP hydrolysis, like other kinesins, for stepping on the microtubule lattice, but at the plus end

181 rmly attached to one microtubule while it is stepping on the other.

182 ass platform; forelimb use was unbiased when stepping onto the glass surface but biased when stepping

183 pping onto the glass surface but biased when stepping onto the other side.

184 ed to the inhabitants of either the Eurasian steppe or Armenia.

185 These results provide support for a steppe origin of at least some of the Indo-European lang

186 Stepping out of an aggressively air-conditioned building

187 Hence, studying culture requires stepping out of it.

188 f the PPC of cats walking on a treadmill and stepping over a moving obstacle whose speed of advance w

189 Second, Dmc1 stepping over infrequent mismatches is likely critical f

190 plastic changes that may be adaptive in non-stepping paraplegia after SCI.

191 structure fully consistent with the variable stepping pattern observed as dynein moves along the MT.

192 The irregular stepping pattern of MyoVc, which may result from flexibi

193 the broad step-size distribution of the MVI stepping pattern.

194 speed and spatiotemporal characteristics of stepping persist.

195 ia following an expansion of people from the steppe, persisted within Europe until the mid-Bronze Age

196 el of precision to an otherwise noisy dynein stepping process.

197 mics of megafauna that inhabited the mammoth steppe provides insights into the causes of extinctions

198 ciates at 2.1 s(-1), 20-fold slower than the stepping rate, demonstrating the presence of rear head g

199 d mant-ADP release is 5-fold faster than the stepping rate.

200 on below the lesion are thus involved in the stepping recovery after an incomplete SCI.

201 We also report a transect of the steppe region in Samara between 5600 and 300 bc, which a

202 o-European languages from the Pontic-Caspian Steppe region.

203 During the Late Neolithic, this Steppe-related impact coincides with the proposed emerge

204 This leaves the accuracy of dynein stepping relatively inaccurate and susceptible to therma

205 ed independently from other core features of stepping, revealing a striking freedom in an otherwise p

206 wever, because sensory feedback entrains the stepping rhythm, it is difficult to reveal central patte

207 eward loads, we found that individual motors stepped sideward in both directions, with and against lo

208 ding that are distinct from the terraces and stepped sites found on polycrystalline Cu foil.

209 oreover, the [Cu2(glu)2(bpa)] MOF displays a stepped sorption isotherm for the uptake of CO2 at room

210 otein from syncytial embryos, which we named Stepping stone (Sstn).

211 symmetric, sparing the basal ganglia, and a stepping stone appearance in the frontal pericallosal re

212 , we show that wood has served not only as a stepping stone between habitats but also as a bridge bet

213 ia intermediate unprotected habitats through stepping stone dispersal.

214 These results provide a stepping stone for engineering more complex nitrogen-ato

215 f molecular recorders, providing a necessary stepping stone for future biological work.

216 power of single-cell RNA-seq and provides a stepping stone for future explorations of cellular heter

217 Hopefully, this review can be used as a stepping stone for the reader wanting to gain a clearer

218 llocation, and this work provides a valuable stepping stone in guiding policy on CSF surveillance and

219 ere that family living acted as an essential stepping stone in the evolution of cooperative breeding

220 erature and argue that these could provide a stepping stone into the identification of scientific bes

221 itment at the single cell level, a potential stepping stone to improved lineage manipulation through

222 This work represents a stepping stone toward a better understanding of the WAF

223 Our work constitutes a stepping stone towards the paradigm of self-correcting q

224 This approach provides a stepping stone towards the rational engineering of molec

225 Our work may be used as a stepping stone towards using the HyperCEST technique as

226 alysis confirms the role of the alkene as a "stepping stone" for electron transfer.

227 ude much of the MPA network that may provide stepping-stone protection for species that must shift th

228 In a first step, we simulated the historical stepping-stone spreading dynamics of 40 marine alien spe

229 cing greenhouse gas emissions and a possible stepping-stone towards renewable synthetic fuels.

230 om land and indicate that islands may act as stepping stones facilitating the transoceanic transport

231 volution, mainly by intermittently providing stepping stones for island colonization.

232 fic and Indian oceans and propose islands as stepping stones for the transoceanic transport of terres

233 points should now be viewed as obstacles or stepping stones is a matter of perspective.

234 iption factor-DNA interactions are important stepping stones towards a mechanistic understanding of m

235 opulations are only connected via additional stepping stones was supported by contemporary migration

236 Milu searched for vacant habitat patches as "stepping stones" and established refuge populations.

237 els provide intermediate states that act as "stepping stones" for electrons tunnelling across the dio

238 l, persisting populations, which can act as "stepping stones" that enable a rapid population expansio

239 d animals were subject to chance in finding "stepping stones".

240 ns requires intermediate habitats ("phantom" stepping stones).

241 th increasing charge stabilization on their "stepping stones." The presence of mobile anions facilita

242 Thus, ribosomal mutations can serve as stepping-stones in an evolutionary path leading to the e

243 hoosing an appropriate fold pattern a target stepped surface can be designed.

244 late transition metals can modify binding at stepped surfaces opposite to well-established trends on

245 a characteristic elastic strain variation at stepped surfaces, and unveil subtle stress-release effec

246 omains along the terraces of atomically flat stepped surfaces.

247 Using a precision stepping task and synchronizing target visibility to the

248 We analyzed experiments in the Patagonian steppe that evaluated the aboveground net primary produc

249 Our work reveals features of base triplet stepping that are conserved among these three phylogenet

250 ysis finds that a number of proteins fold by stepping through a reproducible sequence of native-like

251 ongoing, primarily male, migration from the steppe to central Europe over a period of multiple gener

252 l triggering and other changes in protective stepping to impact fall risk.

253 Stepping towards this goal of incorporating biochemical

254 Non-stepping training also exacerbated some SCI-driven plast

255 f our findings and further assessment of the stepped treatment model is warranted.

256 stigated, Arctic vegetation consisted of dry steppe-tundra dominated by forbs (non-graminoid herbaceo

257 ad bottom-up effects in the Late Pleistocene steppe-tundra ecosystem.

258 l range indicates large-scale changes in the steppe-tundra environment in western Eurasia during the

259 f linear and rotary motors, and explains the stepped unidirectional rotary motion.

260 ntinue to increase as the CO2 enrichment was stepped up to higher concentrations.

261 Vaccination needs to be stepped up to protect persons who remain at risk of HBV

262 e arm, of those with 6 months recurrence who stepped up treatment, 18 (38%) of 47 patients were in re

263 Scientists are stepping up like never before to support science in the

264 rovide evidence for the clinical benefits of stepping up patients with COPD from an inhaled corticost

265 5 V) from the biofuel cell is converted to a stepped-up power and charged to the capacitor to the vol

266 Rutgeerts score >/=i2) at 6 months, patients stepped-up to thiopurine, fortnightly adalimumab with th

267 s with endoscopic recurrence at 6 months who stepped-up treatment, FC levels decreased from 324 mug/g

268 patients in the active care group, 47 (39%) stepped-up treatment.

269 We find evidence of steppe vegetation, bison and mammoth by approximately 12

270 y and membrane viscosity, reaching up to the stepping velocity of single motors.

271 ks that were specifically trained (standing, stepping, volitional leg movement).

272 hat a defining characteristic of the mammoth steppe was its temporal instability and imply that regio

273 plete section (T13) in these cats, bilateral stepping was seen on the next day, a skill usually acqui

274 In the Mongolian steppe, we examined whether leaf functional traits under

275 To examine the role of the NL in regulating stepping, we investigated NL mutants of various lengths

276 To resolve rotations during stepping, we used optical tweezers combined with an opti

277 This was a pragmatic stepped wedge cluster randomized controlled trial evalua

278 A stepped wedge cluster randomized controlled trial was co

279 A multicenter stepped wedge cluster randomized controlled trial.

280 ects of this program in ICU patients using a stepped wedge design.

281 ment (n = 74) or 28 days later (n = 77) in a stepped wedge fashion, allowing comparisons between reci

282 Stepped wedge trials allow investigators to estimate CAC

283 using the IV approach, which are testable in stepped wedge trials but not in parallel-arm trials.

284 This was a multicenter pragmatic stepped-wedge before-and-after trial in 7 New Zealand ac

285 By using a stepped-wedge cluster randomized and controlled trial de

286 We conducted a pragmatic multicenter stepped-wedge cluster randomized controlled trial of a p

287 wer of randomised controlled trial (RCT) and stepped-wedge cluster trial (SWCT) designs in Sierra Leo

288 over three years in central Senegal using a stepped-wedge cluster-randomised design.

289 Using a stepped-wedge design, we tested whether a bundled interv

290 dship audit-and-feedback intervention, via a stepped-wedge randomized trial.

291 In this cluster-randomized, stepped-wedge trial conducted in Tayside, Scotland, we r

292 Stepped-wedge trial.

293 Stepped-wedge, cluster randomized trial.

294 We conducted a stepped-wedge, community-level randomized trial to deter

295 In this stepped-wedge, non-blinded, cluster-randomised controlle

296 Once north of the caldera, the eruption stepped westward, and a dike propagated along the extens

297 Instead, we find that hTpx2 inhibits hKif15 stepping when microtubule-bound.

298 teral left hemisection (T10), cats recovered stepping with both hindlimbs within 3 weeks.

299 at Scythians in the east and the west of the steppe zone can best be described as a mixture of Yamnay

300 aphid, associated with Palaearctic temperate steppe zones or dry mountain valleys, where there are gr