ライフサイエンスコーパス: stepped

1 one- (1.(H2O,EtOH)), two- (1.3H2O) and three-stepped (1.

2 y of macrocycle conformations ranging from a stepped 2 + 2 macrocycle to a multiply folded 8 + 8 macr

3 sphere adsorption to the flat {1014} and the stepped {3148} and {31216} planes of calcite.

4 found to adsorb preferentially on the acute-stepped {3148} face of calcite, in agreement with experi

5 order dendrites exiting from them generally stepped abruptly to a diameter of 0.4-0.6 micrometer, wh

6 t least two varieties of carbonates, using a stepped acid dissolution technique paired with ion micro

7 source, and a calibrated (68)Ge point source stepped across the axial field of view (FOV) provided th

8 A (68)Ge point source was stepped across the axial field of view to measure the se

9 ncidence events as a (22)Na point source was stepped across the coincidence line of response between

10 This resource consists of "Stepped Aligned Inbred Recombinant Strains" (STAIRS) plu

11 These sequence 'walkers' can be stepped along raw sequence data to visually search for b

12 tforms, followed by development of multitier stepped altar platforms and use of pecked basalt stones

13 framework can also undergo a combination of stepped and continuous breathing.

14 ale engineering of these interlayers to form stepped and graded electronic profiles can lead to remar

15 e coupling constants: field-swept, frequency-stepped, and high-field MAS NMR.

16 entage of spinal rats per group that plantar stepped, and was the only group to significantly improve

17 smaller proportion of cells, in response to stepped application of progesterone (3 microM).

18 o treatment strategies are currently used, a stepped approach beginning with more simple care that is

19 The end result is a structured, stepped approach using neurobiological constructs as tar

20 he possibility of improved diagnosis through stepped approaches, epitope-binding analysis, and bioinf

21 In this population-based fMRI study, we stepped back by over a decade to characterize the change

22 Properties of the derived response to a stepped background and to test flashes presented in stea

23 chment and detachment of a barium ion onto a stepped barite (BaSO(4)) surface.

24 m(II) complex "foot" that can be selectively stepped between 4-dimethylaminopyridine and pyridine lig

25 Purpose A stepped care (SC) program in which an effective yet leas

26 of a stepped care case-finding intervention (stepped care [SC]) vs a moderate-strength single-level i

27 zing nonopioid analgesic medications using a stepped care algorithm and monitoring.

28 rity categorization is essential for using a stepped care approach to asthma pharmacotherapy.

29 symptom monitoring with an algorithm-guided stepped care approach to optimizing analgesics.

30 To simulate a comparison of a stepped care case-finding intervention (stepped care [SC

31 , AND PATIENTS: Randomized controlled trial (Stepped Care for Affective Disorders and Musculoskeletal

32 Stepped care interventions can reduce PTSD symptoms and

33 Stepped care is an increasingly popular treatment model

34 In conclusion, stepped care model appeared to be better than CAU in tre

35 r "low-intensity" interventions as part of a stepped care model.

36 atients with major depression were allocated stepped care or usual care.

37 rogram (NAEPP) Expert Panel II recommended a stepped care pharmacotherapy approach to asthma treatmen

38 included in this review, of which 6 examined stepped care prevention and 4 examined stepped care trea

39 mpare the efficacy and cost-effectiveness of stepped care prevention and treatment with care-as-usual

40 No significant difference was found between stepped care prevention/treatment and CAU in preventing

41 The CC patients received stepped care that consisted of (1) continuous postinjury

42 The Stepped Care to Optimize Pain Care Effectiveness (SCOPE)

43 Results showed stepped care treatment revealed a significantly better p

44 nxiety disorders was significantly higher in stepped care treatment than in CAU.

45 mined stepped care prevention and 4 examined stepped care treatment, specifically including ones rega

46 Stepped care was a 3-month, multicomponent intervention

47 Stepped care was associated with greater reach and was s

48 Stepped-care and collaborative models provide a framewor

49 Stepped-care antihypertensive drug therapy, in which the

50 decrease in blood pressure than standardized stepped-care antihypertensive treatment alone.

51 of renal denervation added to a standardized stepped-care antihypertensive treatment for resistant hy

52 eatment, renal denervation plus standardized stepped-care antihypertensive treatment resulted in a gr

53 igned to renal denervation plus standardized stepped-care antihypertensive treatment, or the same ant

54 For standardized stepped-care antihypertensive treatment, spironolactone

55 This stepped-care approach provides a framework for sequencin

56 This paper proposes a stepped-care approach that addresses the functional outc

57 imia nervosa and binge eating disorder, with stepped-care approaches showing promise and new behavior

58 n implemented through collaborative care and stepped-care approaches.

59 At 6-months' follow-up, 70% (60-79) of the stepped-care compared with 30% (21-40) of the usual-care

60 Specialized nurses delivered a 12-month, stepped-care depression treatment program beginning with

61 ividual counseling on a fat-modified diet, a stepped-care drug treatment program for diastolic hypert

62 h community-based workers in a collaborative stepped-care framework is an approach that is ripe to be

63 d four suicide attempts in the collaborative stepped-care group and six deaths and six suicide attemp

64 The collaborative stepped-care intervention offered case management and ps

65 Intervention A stepped-care model for depression treatment was used by

66 Physicians should consider a stepped-care model in which patients may begin with rela

67 ed for initial severity, women receiving the stepped-care program had a mean of 50 additional depress

68 allocated to usual care or a multicomponent stepped-care program led by a nonmedical health care wor

69 The stepped-care program was marginally more expensive than

70 The stepped-care program was significantly more effective an

71 We aimed to compare the effectiveness of a stepped-care programme with usual care in primary-care m

72 nce in all outcome measures in favour of the stepped-care programme.

73 Stepped-care therapy (pravastatin, nicotinic acid, chole

74 ed systolic hypertension with chlorthalidone stepped-care therapy for 4.5 years was associated with l

75 on and dietary reduction of cholesterol, and stepped-care therapy for hypertension.

76 pertensive therapy with chlorthalidone-based stepped-care therapy resulted in a lower rate of cardiov

77 persons with isolated systolic hypertension, stepped-care treatment based on low-dose chlorthalidone

78 r depression responded well to a structured, stepped-care treatment programme, which is being introdu

79 ared the incremental cost-effectiveness of a stepped-care, multicomponent program with usual care for

80 We find that this trait underwent stepped change, from thick to semi-thin to thin seed coa

81 which can be monitored by the corresponding stepped changes in the ion current flowing through the p

82 luated the incremental cost-effectiveness of stepped collaborative care for patients with persistent

83 Stepped collaborative care intervention included motivat

84 A stepped collaborative care program for depressed primary

85 PTSD symptom levels and then randomized to a stepped combined care management, psychopharmacology, an

86 communication in the HKR is mediated by the stepped conformation of the salen ligand, and not the sh

87 lation exhibited a canonical anticodon stair-stepped conformation.

88 ification during the middle Pliocene, sudden stepped cooling events during the Pliocene-Pleistocene t

89 ommunity that inhabited the mountains before stepped cooling that first brought a full polar climate

90 ntrated and selectively released by applying stepped DC voltages across a microchannel containing an

91 The stepped decline is argued to reflect marine downdraw tri

92 ter delta(13)CDIC, the last of a longer-term stepped decrease through the Spathian.

93 received anterior chamber (AC) injections of stepped doses (10(6)-10(8) transduction units) of lentiv

94 col at a lower total dose (0.5-5.0 mSv, with stepped doses of 0.5 mSv).

95 of a block, 20 long-term multifocal wearers stepped down (from different block heights) onto a lower

96 89.4% (95% CI, 86.4% to 92.4%) of those who stepped down had preserved asthma control compared with

97 Following withdrawal of the stepped-down 0.5 mg dose and consequent release into a f

98 In addition, distinct stepped expression levels of hunchback in the gnathal/th

99 , absolute bias of 0.54% to the standardized stepped field (DT)CCSN2 values on the reference system.

100 The traditional stepped field CCS method performs with a relative standa

101 A set of images was recorded at stepped focus settings and analyzed to find the sharpest

102 5-853 kcal/day formula diet for 3-5 months), stepped food reintroduction (2-8 weeks), and structured

103 Three trained and three nontrained rats stepped for 1 h (ES; no quipazine) and were returned to

104 ith similar benefits and adverse effects, a "stepped formulary" approach requiring an initial trial o

105 This segmentation produces stepped fracture surfaces with characteristic 'lance-sha

106 When cells were stepped from -100 to -30 mV in Ca2+-free conditions, sma

107 0) and Scheme 2 where the potential is again stepped from E(start) to E(step) to oxidize A to B under

108 ral schemes: Scheme 1 where the potential is stepped from E(start) to E(step) to oxidize the initiall

109 me liposome-based drug products have already stepped from the lab-bench to the market.

110 a, mood changes, urinary symptoms, and short-stepped gait.

111 ge of glucose concentrations, responses to a stepped glucose infusion were measured in 23 subjects.

112 The response of the CMHs to a stepped heat stimulus (49 degrees C, 3 s) was either qui

113 llion extraterrestrial H(2)O released during stepped heating.

114 Stepped-heating experiments on martian meteorites Allan

115 age, where {100} facets roughen into vicinal stepped high Miller index facets, while {111} facets rem

116 Kinked-stepped, high Miller index surfaces of metal crystals ar

117 l glucose reabsorption was measured with the stepped hyperglycemic clamp in 15 subjects with type 2 d

118 hed for age, sex, and body mass index with a stepped hyperinsulinaemic hypoglycaemic glucose clamp.

119 Using functional MRI (fMRI) combined with a stepped hyperinsulinemic euglycemic-hypoglycemic clamp a

120 placebo-controlled cross-over trial using a stepped hyperinsulinemic hypoglycemia clamp was performe

121 ted type 1 diabetic subjects participated in stepped hyperinsulinemic- (2 mU x kg(-1) x min(-1)) eugl

122 ter intrahepatic islet transplantation using stepped hyperinsulinemic-hypoglycemic and paired hyperin

123 On day 2, all were studied with stepped hyperinsulinemic-hypoglycemic clamps, using horm

124 Using stepped hypoglycemia clamp studies (5.0, 4.4, 3.9, and 3

125 reatic polypeptide (P = 0.0046) responses to stepped hypoglycemia were reduced significantly, and sym

126 and cognitive responses to hyperinsulinemic stepped hypoglycemic (4.7, 4.2, 3.6, 3.0, 2.8, 2.5, and

127 hyperinsulinemic (2.0 mU x kg(-1) x min(-1)) stepped hypoglycemic (85, 75, 65, 55, and 45 mg/dl) clam

128 and during euglycemic-hyperinsulinemic then stepped hypoglycemic (hourly steps at 85, 75, 65, 55, an

129 ched control subjects were studied utilizing stepped hypoglycemic clamp protocol to achieve target gl

130 We performed stepped hypoglycemic clamp studies in successful pancrea

131 Hyperinsulinemic stepped hypoglycemic clamps (85, 75, 65, 55, and 45 mg/d

132 ere assessed during morning hyperinsulinemic stepped hypoglycemic clamps (85, 75, 65, 55, and 45 mg/d

133 betic control subjects with hyperinsulinemic stepped hypoglycemic clamps (glucose steps of approximat

134 On day 2, subjects underwent stepped hypoglycemic clamps (nadir 60 mg/dL) with evalua

135 Consequently, we performed stepped hypoglycemic clamps in 7 donors of varying glyce

136 subjects were studied with hyperinsulinemic-stepped hypoglycemic clamps the day after saline or cort

137 ction tests deteriorated (P < 0.0001) during stepped hypoglycemic clamps, but there were no significa

138 ps of pancreas transplant recipients using a stepped hypoglycemic, hyperinsulinemic clamp.

139 approximately 5 years earlier using the same stepped, hypoglycemic clamp technique.

140 s is fraught with challenges, and often side-stepped in favour of studying the function of different

141 nucleus to a vertical bar stimulus that was stepped in small increments through the receptive fields

142 e observed by 7 d, when only trained KO mice stepped in the open field.

143 orescence emission red shift and an apparent stepped increase in fluorescence intensity.

144 screening mammography increased, yielding a stepped increase in women recalled per cancer detected f

145 interventions led to smaller but significant stepped increases compared with the automated interventi

146 (somatostatin/glucagon/growth hormone) with stepped insulin levels.

147 ation of artificial nanofluidic devices have stepped into a completely new stage, termed 2D nanofluid

148 A gunman with a semiautomatic weapon stepped into a tourist coffee shop and systematically sh

149 reas beta-RbBi(3)Se(5) and CsBi(3)Se(5) have stepped layers with alkali metal ions found disordered i

150 clinical decision making that involves four stepped levels, proceeding from the lowest to the highes

151 ful symptom relief and low mortality through stepped management, adding disopyramide in appropriately

152 still survive with an anisotropic etched and stepped nanotip at temperatures up to 800 degrees C, muc

153 Monkeys tracked a target that stepped obliquely away from the point of fixation, then

154 Demonstrator pigeons (Columba livia) stepped on a treadle in the presence of 1 light and peck

155 The response to stepped onset of an approximately half-saturating backgr

156 , and persistent congestion to a strategy of stepped pharmacologic therapy (94 patients) or ultrafilt

157 ion, and persistent congestion, the use of a stepped pharmacologic-therapy algorithm was superior to

158 Here we describe a two-stepped photobiotin-based procedure to enrich a target (

159 tation is presented for the magnetism of the stepped pi-chain of 2 using an alternating Heisenberg ch

160 structure and geometry optimizations on the stepped pi-chain, the isolated molecule and (di)cations

161 We found that stepped platinum (Pt) surfaces can undergo extensive and

162 tions, we study the adsorption of water on a stepped platinum surface.

163 ce of 61 pS was found when the Cx43 cell was stepped positively or the Cx40 cell negatively (V(j)=70

164 o adequately resolve by means of traditional stepped potential protocols.

165 a recombinant human construct Eg5-513-5His, stepped processively along microtubules in 8-nm incremen

166 strated behavior of water chains adsorbed on stepped Pt surfaces to transfer protons via thermally ac

167 at are otherwise invisible when conventional stepped pulses are applied.

168 opriate samples is evolved by a procedure of stepped pyrolysis (0-1000 degrees C, typically in 50 deg

169 t will be shown that nitrogen formation on a stepped rhodium surface is a dynamic interplay of atomic

170 (stationary spot) revealed Ca2+ sparks with "stepped' rises, consistent with multiple sites of origin

171 For the dihydride-stepped Si(111) surface, a unique reaction pathway is id

172 eward loads, we found that individual motors stepped sideward in both directions, with and against lo

173 n this article we predict theoretically that stepped silicon surfaces stabilized by adsorbed gold ach

174 Stepped single-crystal surfaces are viewed as models of

175 ding that are distinct from the terraces and stepped sites found on polycrystalline Cu foil.

176 oreover, the [Cu2(glu)2(bpa)] MOF displays a stepped sorption isotherm for the uptake of CO2 at room

177 ered cubic metals such as Cu have kinked and stepped structures which are nonsuperimposable mirror im

178 hoosing an appropriate fold pattern a target stepped surface can be designed.

179 late transition metals can modify binding at stepped surfaces opposite to well-established trends on

180 a characteristic elastic strain variation at stepped surfaces, and unveil subtle stress-release effec

181 tle is known about the chemistry of water on stepped surfaces, commonly occurring in realistic situat

182 omains along the terraces of atomically flat stepped surfaces.

183 ease in amplitude to go directly to the back-stepped target location.

184 Lower olefins are produced at promoted (stepped) terrace sites that are available and active, qu

185 pontaneous release; and when the voltage was stepped to >-40 mV, secretion ensued.

186 Cells were voltage clamped at -30 mV and stepped to -120 mV in 10 mV steps of 2 s duration.

187 Using a moving pursuit stimulus that stepped to a new spatial location just before a targetin

188 In this method, the applied force is rapidly stepped to a new value and either the unfolding or refol

189 med, it persists even after the potential is stepped to higher values (0.5-0.8 V(SCE)).

190 When the outer segment of the cone was stepped to low-Ca(2+)-O Na+ solution before the bleach w

191 currents were restored when the patches were stepped to negative potentials.

192 lamp mode, the cells were held at -60 mV and stepped to values from -60 to 80 mV.

193 time scale than unfolding and involves sharp stepped transitions.

194 2) vs standard (n=247) treatment groups with stepped treatment algorithms defined for both.

195 to specialty centers or for the selection of stepped treatment algorithms.

196 f our findings and further assessment of the stepped treatment model is warranted.

197 Stepped-treatment approaches customize interventions bas

198 f linear and rotary motors, and explains the stepped unidirectional rotary motion.

199 Thus, we have stepped up the computational strategy using a protocol b

200 ntinue to increase as the CO2 enrichment was stepped up to higher concentrations.

201 Vaccination needs to be stepped up to protect persons who remain at risk of HBV

202 e arm, of those with 6 months recurrence who stepped up treatment, 18 (38%) of 47 patients were in re

203 ented global warming, only extraordinary and stepped-up conservation efforts will prevent a new round

204 5 V) from the biofuel cell is converted to a stepped-up power and charged to the capacitor to the vol

205 ipants randomized to receive MTX monotherapy stepped-up to combination therapy at 24 weeks if the Dis

206 Rutgeerts score >/=i2) at 6 months, patients stepped-up to thiopurine, fortnightly adalimumab with th

207 s with endoscopic recurrence at 6 months who stepped-up treatment, FC levels decreased from 324 mug/g

208 patients in the active care group, 47 (39%) stepped-up treatment.

209 This was a pragmatic stepped wedge cluster randomized controlled trial evalua

210 A stepped wedge cluster randomized controlled trial was co

211 A multicenter stepped wedge cluster randomized controlled trial.

212 rapy with RUTF (992 children) according to a stepped wedge design to control for bias introduced by t

213 ects of this program in ICU patients using a stepped wedge design.

214 ment (n = 74) or 28 days later (n = 77) in a stepped wedge fashion, allowing comparisons between reci

215 Stepped wedge trials allow investigators to estimate CAC

216 using the IV approach, which are testable in stepped wedge trials but not in parallel-arm trials.

217 Inclusion of CACE estimates in stepped wedge trials with imperfect compliance could enh

218 e a method for estimating CACE in randomized stepped wedge trials, where experimental units cross ove

219 This was a multicenter pragmatic stepped-wedge before-and-after trial in 7 New Zealand ac

220 DESIGN, SETTING, AND PATIENTS: Prospective stepped-wedge clinical practice study of 6290 adults adm

221 By using a stepped-wedge cluster randomized and controlled trial de

222 We conducted a pragmatic multicenter stepped-wedge cluster randomized controlled trial of a p

223 wer of randomised controlled trial (RCT) and stepped-wedge cluster trial (SWCT) designs in Sierra Leo

224 over three years in central Senegal using a stepped-wedge cluster-randomised design.

225 Using a stepped-wedge design, we tested whether a bundled interv

226 dship audit-and-feedback intervention, via a stepped-wedge randomized trial.

227 In this cluster-randomized, stepped-wedge trial conducted in Tayside, Scotland, we r

228 Stepped-wedge trial.

229 Stepped-wedge, cluster randomized trial.

230 We conducted a stepped-wedge, community-level randomized trial to deter

231 In this stepped-wedge, non-blinded, cluster-randomised controlle

232 Once north of the caldera, the eruption stepped westward, and a dike propagated along the extens