ライフサイエンスコーパス: sterile

1 s developed with normal morphology, but were sterile.

2 iosis, which renders Cdk2 knockout (KO) mice sterile.

3 ccurs because staying individuals are rarely sterile.

4 ve growth and development and are completely sterile.

5 idopsis (Arabidopsis thaliana), was not male sterile.

6 sence, sperm does not form and male mice are sterile.

7 n breast tissue and milk were presumed to be sterile.

8 female mice homozygously null for ALADIN are sterile.

9 nancy and was traditionally considered to be sterile.

10 mints have complex polyploid genomes and are sterile.

11 1) purifies with coactivators Fs(1)h [female sterile (1) homeotic] and Enok/Br140 during embryogenesi

12 STE20 (Sterile 20)/SPS-1 related proline/alanine-rich kinase (S

13 STE20 (Sterile 20)/SPS-1 related proline/alanine-rich kinase (S

14 Recent findings have associated mammalian sterile 20-like kinase 1 (MST1) loss of function with a

15 of the human kinome, we found that mammalian sterile 20-like kinase 1 (Mst1), but not Mst2, profoundl

16 dispensable for HCC formation when mammalian sterile 20-like kinase 1 and 2 (Mst1 and Mst2) were remo

17 n promoted the activation of Mst1 (mammalian sterile 20-like kinase 1) and the inhibition of Yap (Yes

18 ng was obtained under aseptic condition with sterile 21 gauge needle by an ophthalmologist from patie

19 tion and contextualization of infectious and sterile agents to the adaptive immune system.

20 d microhabitat for marine bacteria by adding sterile alginate particles to microcosms with seawater f

21 uble-crossover events that replaced a female-sterile allele of the singed gene (sn(X2)) on FM7c with

22 s discovered that genetic deletion of SARM1 (sterile alpha and TIR motif containing protein 1) dramat

23 Sterile alpha and Toll/interleukin receptor (TIR) motif-

24 dies previously revealed that the N-terminal sterile alpha motif (or SAM) domain of SMSr drives self-

25 s), Eph receptors are unique in possessing a sterile alpha motif (SAM domain) at their C-terminal end

26 Sterile alpha motif (SAM) and histidine-aspartic (HD) do

27 an intron of Samd14 (Samd14-Enh) encoding a sterile alpha motif (SAM) domain protein.

28 The C terminus of Shank3 contains a sterile alpha motif (SAM) domain that is essential for i

29 13, Tyr-128, and Tyr-145, "3Y") as well as a sterile alpha motif (SAM) domain whose function is uncle

30 tructures of the polymerizing TNKS and TNKS2 sterile alpha motif (SAM) domains, revealing versatile h

31 isrupting the polymerization activity of the sterile alpha motif (SAM) of the PcG protein Polyhomeoti

32 SAMHD1 (sterile alpha motif and HD domain-containing protein 1)

33 SAMHD1 (sterile alpha motif and histidine (H) aspartate (D) doma

34 We found that sterile alpha motif and histidine-aspartate domain-conta

35 ctor in stressful conditions, the MAP3K ZAK (Sterile alpha motif and leucine zipper-containing kinase

36 We found that ankyrin repeat and sterile alpha motif domain containing 4B (ANKS4B) locali

37 nse mutation (c.2640C>A, p.His880Gln) in the sterile alpha motif domain containing 9-like gene (SAMD9

38 o identify de novo heterozygous mutations in sterile alpha motif domain-containing protein 9 (SAMD9,

39 ruitment, highlighting the essential role of Sterile Alpha Motifs.

40 Domain deletion analysis showed that the sterile alpha-motif of Mst50 but not the Ras-association

41 cking the mouse Toll receptor adaptor Sarm1 (sterile alpha/Armadillo/Toll-Interleukin receptor homolo

42 ed tRNA-binding domain of Tric1 and Tric2, a sterile-alpha-motif at the C-terminal end of the protein

43 enerates a C-terminal domain that contains a sterile-alpha-motif-like domain.

44 ches is considered incompatible as MAT kills sterile and 'wild' males indiscriminately.

45 In addition, Fgssn3 was female sterile and defective in hypopodium formation and infect

46 amino acid sequence homology to cyclins, are sterile and display meiotic defects virtually identical

47 Alk3 cKO mice are sterile and have defects in the luminal uterine epitheli

48 otal for host inflammatory responsiveness to sterile and infectious insults.

49 nterfeit bevacizumab has caused outbreaks of sterile and infectious postinjection endophthalmitis in

50 They are usually considered sterile and innocuous as a result of nonsense-mediated m

51 However, these mice are sterile and it is unclear whether the observed skeletal

52 genomic background: motile sperm, no sperm (sterile), and immotile sperm.

53 ut mutants of MPK1 were severely dwarfed and sterile, and homozygous mpk1 seeds from heterozygous par

54 ila melanogaster and Drosophila simulans are sterile, and phenocopy mutations in the PIWI interacting

55 pecies often result in male hybrids that are sterile, and the molecular and functional basis of genet

56 pecific enhancer that regulates the level of STERILE APETALA (SAP) protein in the developing petals.

57 single copy anther-specific gene with a male sterile Arabidopsis knockout phenotype is also in the Y-

58 Neuroinflammation is sterile, as damage-associated molecular patterns rather

59 It is fertile at room temperature but male sterile at modestly elevated temperature (ET).

60 formation at baseline and upon microbial or sterile autoimmune stimuli.

61 22; I2 = 63.7%, 95% CI 4.4%-86.2%), use of a sterile blade to cut the umbilical cord (1.88, 1.25-2.82

62 t analysis of a single infecting genome in a sterile blood specimen are available and have recently b

63 ction of pneumococcus in a relevant normally sterile body fluid.

64 ade by culturing Listeria monocytogenes from sterile body fluids or from products of conception.

65 -fixed, paraffin-embedded (FFPE) tissues and sterile body fluids with known diagnosis of IFD based on

66 We cultured blood and other normally sterile body fluids, reconfirmed and serotyped pneumococ

67 was defined as MRSA cultured from a normally sterile body site in a patient discharged from a hospita

68 In the setting of non-penetrating TBI, sterile brain inflammatory responses are associated with

69 es (MDMs) contribute to recovery after acute sterile brain injury.

70 branches terminate in either a spikelet or a sterile bristle, and these structures appear to be paire

71 s previously been reported in the context of sterile cell death.

72 ttlenecks enables efficient mating by these "sterile" cell types.

73 iven by inflammation caused by infections or sterile cellular stress.

74 The isolation ofActinomycesspp. from sterile clinical samples is traditionally regarded as si

75 Samples were sterile, colorless, and radiochemically pure (100%); mai

76 was produced from plant callus tissue under sterile conditions to avoid the influence of pathogen-as

77 Under sterile conditions, 1 muL Enterococcus faecalis was inoc

78 Although placement of gamma-irradiated sterile cornea (GISC) as a patch graft over the tube is

79 rred in the T-ionto CL group; 1 eye (8%) had sterile corneal infiltrates, which did not affect the fi

80 Gamma-irradiated sterile corneal patch grafts do not always retain their

81 about root exudation chemistry are based on sterile cultivation systems, which limits the discovery

82 mination, suspended in test tubes containing sterile culture broth, and followed for 5 days.

83 induce tyloses in intact plantlets grown in sterile culture.

84 creased from approximately 4000 at time 0 to sterile cultures at 3 hours.

85 mice when CYP metabolism was inhibited, with sterile cure achieved in one mouse.

86 manid at 30 mg kg(-1) for 5 days resulted in sterile cures in a mouse model of VL.

87 s and 20 healthy implants was collected with sterile curets from 30 participants.

88 during skeletal muscle regeneration after a sterile damage.

89 The RADPAD is a sterile, disposable, lead-free shield placed on the pati

90 vpr-1 null mutants are maternal effect sterile due to arrested gonadogenesis following embryo h

91 ptor complex, the null coi1-1 mutant is male sterile due to lack of JA perception.

92 The male knockout mice were sterile due to the arrest of spermatogenesis at an early

93 ytoplasmic genomes, and its flowers are male sterile due to the foreign mitochondrial genome.

94 The high level of sterile efficacy observed in this trial is encouraging f

95 erant seedlings grew similarly when provided sterile EMF inoculum, but drought-tolerant seedlings gre

96 ed mice during both polymicrobial sepsis and sterile endotoxemia.

97 Thus, our integrated device with sterile environment and convenient use will be a promisi

98 Although human blood is believed to be a sterile environment, recent studies suggest that pleomor

99 n the context of infection is different from sterile-environment-induced cell death and that inhibiti

100 platforms that detect microbial substances, sterile environmental insults, and molecules derived fro

101 aiian picture-winged Drosophila that produce sterile F1 males but fertile F1 females, a pattern consi

102 We investigated whether sterile fecal filtrates (containing bacterial debris, pr

103 lture of human adult peripheral T cells with sterile fecal water from NGM3 subjects increased the pro

104 The pollination of BnCysP1 male-sterile (female-fertile) plants with BnCysP1Si pollen re

105 rences are apparent between reproductive and sterile females, males and females, and workers that dif

106 Stool was sterile-filtered to remove small particles and bacteria;

107 f 5 patients with CDI shows that transfer of sterile filtrates from donor stool (FFT), rather than fe

108 After labeling, neutralization, sterile filtration and quality control (instant thin-lay

109 The dominant male-sterile gene Ms2 in common wheat has facilitated the rel

110 group (2.1%) and 121 of 6040 patients in the sterile glove group (2.0%).

111 related to operating room attire except for sterile gowns and the use of gloves.

112 Hybrid males are sterile, however, preventing the establishment of stable

113 Comparisons of fertile and sterile hybrid males identified a set of genes that were

114 amniotic infection) or danger signals (i.e., sterile IAI) has been implicated in the pathogenesis of

115 ignificantly higher in MIAC than in cases of sterile IAI.

116 actors that are critical to the induction of sterile immunity against parasite reinfection.

117 Sterile immunity can be elicited in humans by immunizati

118 T cells were essential for the induction of sterile immunity during whole-organism vaccination.

119 exposures would induce protective long-lived sterile immunity targeting pre-erythrocytic stage parasi

120 at ameliorate organ damage in the setting of sterile immunopathology.

121 vealed that the lungs, previously considered sterile in health, harbor diverse communities of microbe

122 of genes that were uniquely misexpressed in sterile individuals.

123 ndritic cells from day 2 postinfection or by sterile induction of type I IFN.

124 e screening strategy induce a high degree of sterile infection-blocking protection against sporozoite

125 Three eyes (0.4%) developed sterile infiltrates, 1 (0.1%) had delayed epithelial hea

126 els of CCR5, responsible for their homing to sterile inflamed tissues.

127 of probe 3 was observed in murine models of sterile inflammation and carotid aneurysm.

128 rrent preclinical and clinical evidence that sterile inflammation and inflammasome-dependent signalin

129 al for anti-fungal immunity, but its role in sterile inflammation and oncogenesis has not been well d

130 ts strongly suggest that EVs cause placental sterile inflammation and PE through activation of matern

131 Tumor infiltration of RT-Ns resulted in sterile inflammation and, eventually, the activation of

132 olecules released by dead cells that trigger sterile inflammation and, in vertebrates, adaptive immun

133 transcriptome revealed that IDR-1002 reduced sterile inflammation by suppressing the expression of tr

134 ferentiating active bacterial infection from sterile inflammation can be difficult using current imag

135 Although sterile inflammation has recently been shown to boost co

136 etect and differentiate infection sites from sterile inflammation in mice (P = 0.03).

137 r sensor in triggering macrophage-associated sterile inflammation in obesity.

138 of these molecules as central initiators of sterile inflammation in response to nonlethal stress, a

139 hat associates with NF-kappaB, in control of sterile inflammation in the pancreas and biliary system

140 This was associated with increased sterile inflammation in the skin in the same subjects re

141 oinflammatory disorder developing largely as sterile inflammation in the vessel wall.

142 immune cell function, however, their role in sterile inflammation in venous thrombosis has not been s

143 rTK) receptor in cultured macrophages and in sterile inflammation in vivo promotes SPM biosynthesis b

144 This was confirmed in a model of sterile inflammation in vivo.

145 e both E. coli and S. aureus infections from sterile inflammation in vivo.

146 s the hypothesis that systemic stress-evoked sterile inflammation is initiated by the sympathetic ner

147 creas that is considered to be a paradigm of sterile inflammation leading to systemic multiple organ

148 However, dysregulated sterile inflammation leads to various acute and chronic

149 ut how they are generated and their roles in sterile inflammation remain unclear.

150 We propose that sterile inflammation should be considered an elemental f

151 e investigated the role of serum iron in the sterile inflammation that follows kidney ischemia-reperf

152 ue injury contributes to the misdirection of sterile inflammation to promote chronic inflammatory dis

153 ld rapidly differentiate true infection from sterile inflammation to selectively localize E. coli inf

154 neutrophil recruitment and functions during sterile inflammation triggered by fMLF.

155 In a model of sterile inflammation utilizing TLR4 ligation followed by

156 Differentiation of infection from sterile inflammation was investigated using microbiology

157 We observed that RT induced sterile inflammation with a rapid and transient infiltra

158 lammation in the absence of micro-organisms (sterile inflammation), necrotic cells release damage-ass

159 re due to endogenous processes (often called sterile inflammation).

160 mmon pathologic processes such as infection, sterile inflammation, and cancer both clinically and usi

161 ents that accumulate similarly in infection, sterile inflammation, and neoplastic tissue and then ext

162 ress-evoked cytokine/chemokine responses, or sterile inflammation, can facilitate host survival and/o

163 iew will introduce the reader to pathogen vs sterile inflammation, inflammatory receptor-ligand inter

164 During sterile inflammation, necrotic cells release pro-inflamm

165 6 significantly decreased hepatic markers of sterile inflammation, such as C-X-C motif chemokine 1, C

166 protein (HMGB1), a prototypical mediator of sterile inflammation, to be a master regulator of the pr

167 ils are recruited from the blood to sites of sterile inflammation, where they are involved in wound h

168 decade unraveled the molecular mechanisms of sterile inflammation, which established danger signaling

169 for iNKT cell responses in various types of sterile inflammation.

170 ing of the fundamental mechanisms underlying sterile inflammation.

171 renal ischemia-reperfusion injury-associated sterile inflammation.

172 tivates toll-like receptor 4 (TLR4)-mediated sterile inflammation.

173 death and stress, and are potent triggers of sterile inflammation.

174 at control physiological versus pathological sterile inflammation.

175 n of Mac-1 and neutrophil recruitment during sterile inflammation.

176 tial role for Mincle in diseases governed by sterile inflammation.

177 of heat shock-treated S. aureus to generate sterile inflammation.

178 immune cell trafficking to sites of hepatic sterile inflammation.

179 ognizes endogenous danger signals triggering sterile inflammation.

180 nisms that control NF-kappaB activity during sterile inflammation.

181 especially in the areas of tissue injury and sterile inflammation.

182 ecognition and the subsequent development of sterile inflammation; however, the underlying molecular

183 nt in the context of numerous infectious and sterile inflammatory conditions.

184 vity has also been implicated in many common sterile inflammatory conditions.

185 treat autoimmune disease, cancer, and other sterile inflammatory disorders.

186 nflammatory hyporesponsiveness of GF mice in sterile inflammatory injury induced by intestinal ischem

187 R4) activation by bacterial infection, or by sterile inflammatory insult is a primary trigger of spon

188 data have significant implications for acute sterile inflammatory insults such as stroke and traumati

189 disulfide HMGB1 is a central mediator of the sterile inflammatory process in venous thrombosis and co

190 Labor per se is considered a sterile inflammatory process.

191 owever, only recently have the importance of sterile inflammatory processes in this effect been revea

192 as been identified as an important driver of sterile inflammatory processes.

193 The sterile inflammatory response (inflammation in the absen

194 0, IL-1, IL-18, and TNFalpha indicative of a sterile inflammatory response (SIR) in the parenchyma.

195 to be the key player in the CXCL10-mediated sterile inflammatory response in murine NASH.

196 ve been recognized as signaling mediators of sterile inflammatory responses after trauma and injury.

197 ir recruitment to damaged tissues upon acute sterile injuries is necessary for clearance of necrotic

198 Altered cellular composition prior to acute sterile injury affects the in situ phenotypic transition

199 f double-stranded RNA in the pathogenesis of sterile injury following lung contusion.

200 Multiple pathways drive the sterile injury response in the liver; however, it is unc

201 The sterile insect technique (SIT) and cue-lure (a synthetic

202 ns have been prevented and controlled by the sterile insect technique (SIT) as part of integrated pes

203 of biologically-based programs, such as the sterile insect technique (SIT), to control D. suzukii an

204 us for genetic control programs based on the sterile insect technique (SIT).

205 ation of inflammasomes during pathogenic and sterile insults.

206 grees C) chromosomal XX females developed as sterile intersexuals with a predominant male phenotype,

207 possible for many men previously considered sterile, it is crucial to discover and abrogate causes a

208 TLR4- and type I IFN-independent pathway of sterile liver injury in which hepatocytes are both the t

209 Using sterile liver injury models, we show that the STAT3-IL-1

210 of selective hepatocyte death to investigate sterile liver injury.

211 inflammation is critical for determining why sterile maladaptive cardiovascular inflammation perpetua

212 a temperature-dependent system for creating sterile male populations useful for enhancing the effica

213 Sterile male releases have successfully reduced local po

214 d transposable elements (TEs) between hybrid sterile males and its parental nematode males.

215 n, with potential for reducing the number of sterile males to be released.

216 A lower number of RK supplemented sterile males were recaptured in MAT baited traps in bot

217 -baited traps while simultaneously releasing sterile males) is increasing the ratio of sterile to wil

218 We use two lines of hybrid sterile males, each carrying an independent introgressio

219 ges and orchard trials compared to RK denied sterile males.

220 Furthermore, sterile Mincle ligands and Mincle signaling intermediate

221 in large-scale, low-cost production of male-sterile (ms) female lines necessary for hybrid wheat see

222 The male-sterile ms2 mutant has been known for 40 years and has b

223 Macrophages recruited at the site of sterile muscle damage play an essential role in the rege

224 ophage phenotypic transition following acute sterile muscle injury.

225 A seed-sterile mutant with a disrupted TRAF-like gene (At5g2629

226 The microarray datasets from nine rice male sterile mutants, including msp1-4, ostdl1a, gamyb-2, tip

227 The rate of male-specific inviable or sterile mutations is 5 x 10(-4)/generation, below the ra

228 HIGH RESPONSE (HR), DIE NEUTRALIS (DNE), and STERILE NODES (SN), have recently been shown to correspo

229 Sterile (noninfected) inflammation underlies the pathoge

230 In both conditions, a sterile or infectious trigger is required for disease in

231 of producing diploid males, which are often sterile or inviable, sl-CSD can generate substantial inb

232 ne cells recruited during the development of sterile or microbial inflammation.

233 gone 12275 unique outpatient procedures with sterile or nonsterile gloves and had follow-up regarding

234 ed organs have worse transplant outcome than sterile organs, we tested the influence of host and dono

235 restricted by difficulties in demonstrating sterile parasitological cure.

236 We demonstrate that alum, as well as other sterile particulates, such as uric acid crystals, induce

237 A sterile pericarditis model was created using atrial surf

238 STAT3 and miR-21, were highly upregulated in sterile pericarditis rats.

239 ion, alleviated atrial remodeling, abrogated sterile pericarditis-induced inhomogeneous conduction, a

240 -17A expression and function in experimental sterile peritonitis and autoimmune arthritis, respective

241 tion of MerTK is linked to the resolution of sterile peritonitis and, after ischemia-reperfusion (I/R

242 ar results were observed in a model of acute sterile peritonitis.

243 The F1 seeds obtained from BnCysP1 male-sterile plants and untransformed controls showed 1:1 (to

244 ence underlines a pathogenic contribution of sterile postinjury inflammation in APAP-induced acute li

245 Since the demonstration of sterile protection afforded by injection of irradiated s

246 le (VLP) known as Rv21, able to provide 100% sterile protection against a stringent sporozoite challe

247 sporozoite vaccine (PfSPZ Vaccine), confers sterile protection against controlled human malaria infe

248 adjuvants Abisco-100 and Matrix-M it elicits sterile protection against transgenic sporozoite challen

249 VaccineHT(TM), enhanced vaccine efficacy and sterile protection following malaria challenge.

250 e is no licensed vaccine capable of inducing sterile protection.

251 protective CD8 T cell responses and ablated sterile protection.

252 fTRAP, vaccine efficacy was improved to 100% sterile protection.

253 with attenuated whole sporozoites can induce sterile protective immune responses targeting preerythro

254 kin of male Sprague-Dawley rats with a 10-mm sterile punch.

255 Characterized by sterile pustules, erosions, and crusts, EPD is difficult

256 Final sterile, pyrogen-free formulation was provided in physio

257 y-oxylipins in a well-characterized model of sterile resolving peritonitis in the mouse.

258 er sites, constitutive COX-2 expression is a sterile response, independent of commensal microorganism

259 he comprehensive metabolite profiling of non-sterile rhizosphere soil, which represents a technical a

260 od for untargeted metabolic profiling of non-sterile rhizosphere soil.

261 ne, 20% citric acid, 24% EDTA/1.5% NaOCl, or sterile saline and assessed surface physicochemical prop

262 Sterile saline, citric acid, and NaOCl-EDTA may be propo

263 Columns 50 cm long were filled with sterile silica sand following five different setups comb

264 We analysed sterile site cultures for H influenzae type b from child

265 PD as pneumococcal isolation from a normally sterile site in a resident from 10 US surveillance sites

266 ociated MRSA cases (isolated from a normally sterile site of an outpatient or on hospital admission d

267 sive GAS as isolation of GAS from a normally sterile site or from a wound in a patient with necrotizi

268 piratory specimens or 2) NTM cultured from a sterile site with a compatible clinical syndrome.

269 ation or >/=1000 g, with GBS isolated from a sterile site) as a percentage of total stillbirths.

270 uid (24%), ophthalmologic cultures (8%), and sterile sites (20%).

271 to colonizing organisms that gain access to sterile sites via disrupted epithelial barriers.

272 Here, using an acute sterile skeletal muscle injury model combined with irrad

273 ce both self-fertile (large-spores) and self-sterile (small-spores) offsprings in a 4:4 ratio.

274 Using a sterile soft contact lens as scaffold, the tissue was lo

275 Candida guilliermondii was isolated from sterile specimens with increasing frequency over a sever

276 f the MAT1-1-1 gene) was present in the self-sterile strain.

277 etely deleted from the MAT locus in the self-sterile strain.

278 s at MAT locus of both self-fertile and self-sterile strains, found four mating type genes (MAT1-1-1,

279 ion, Plcz1(-/-) males are subfertile but not sterile, suggesting that in the absence of PLCzeta, spon

280 irds have begun to re-colonize the initially sterile surface.

281 ed diseases ranging from bacterial sepsis to sterile syndromes such as major trauma.

282 as created using atrial surfaces dusted with sterile talcum powder in rats.

283 In addition to stringent sterile techniques, an efficacious way to prevent this d

284 Here we show that in a fully repairing sterile thermal hepatic injury, neutrophils also penetra

285 anismal stresses from pathogen infection and sterile tissue injury.

286 study how biofilm might be transferred into sterile tissue/implant materials during injections for j

287 ng sterile males) is increasing the ratio of sterile to wild males in the field population, with pote

288 iously identified role for PTIP in promoting sterile transcription at the Igh locus, the present resu

289 expression of functional, nonproductive, and sterile transcripts of the kappa clusters compared with

290 face and other isotypes as nonproductive VJ, sterile transcripts, or in-frame VJ whose products may n

291 microbiota and thus indicative of a role for sterile triggers.

292 ipotent stem cells (iPSCs), fibroblasts from sterile trisomic XXY and XYY mice lose the extra sex chr

293 Sterile untreated surfaces were the controls.

294 g postoperative complication, which included sterile vitreitis, endophthalmitis, hypotony maculopathy

295 Whether the use of sterile vs nonsterile gloves in outpatient cutaneous pro

296 Studies with information on sterile vs nonsterile gloves in outpatient surgical proc

297 utpatient surgical procedures performed with sterile vs nonsterile gloves.

298 After sterile washing steps, sand flies were dissected and gut

299 n intensified disinfection protocol and used sterile water for heater-cooler units of cardiopulmonary

300 andida albicans, white cells are essentially sterile, whereas opaque cells are mating-proficient.