ライフサイエンスコーパス: sterility

1 omatic segments of the genome contributes to sterility.

2 was insufficient to explain the majority of sterility.

3 rphology during oogenesis, leading to female sterility.

4 f a phytotoxic barnase and provides for male sterility.

5 PD-C expression caused female, but not male, sterility.

6 en in whom germ cell loss is associated with sterility.

7 oxylase (C3'H), exhibits severe dwarfism and sterility.

8 loidy levels is often associated with hybrid sterility.

9 e incidence of male or female infertility or sterility.

10 ex is complicated by complete F1 male hybrid sterility.

11 , provoking prophase arrest and, ultimately, sterility.

12 fferentiation and resulted in increased male sterility.

13 (-/-) doubly null mice led to inducible male sterility.

14 eem by itself to contribute to equine hybrid sterility.

15 association of childhood radiation dose and sterility.

16 sults in both meiotic catastrophe and female sterility.

17 so compromises genome integrity, leading to sterility.

18 esults in the formation of ovarian cysts and sterility.

19 n alpha-subunit GNAT3 leads to male-specific sterility.

20 gument development arrest, leading to female sterility.

21 ient tissue-specialized defenses to maintain sterility.

22 ed an early arrest of floral development and sterility.

23 chromosomal epistatic basis to hybrid female sterility.

24 thality, eye defects, reduced fecundity, and sterility.

25 er-specific Ms2 activation that confers male sterility.

26 ompatibilities contribute to some aspects of sterility.

27 ts overexpressing PAE1 exhibited severe male sterility.

28 s the destruction of germ cells and leads to sterility.

29 tive or hormetic response, resulting in less sterility.

30 vation of CDKF;1 causes extreme dwarfism and sterility.

31 prevents spermiogenesis, and results in male sterility.

32 cycles of spermatogenesis, resulting in male sterility.

33 le mutants exhibit severe growth defects and sterility.

34 y absent two weeks after birth, resulting in sterility.

35 d observed disrupted spermiogenesis and male sterility.

36 rmation and function that ultimately lead to sterility.

37 ybrid incompatibility underlying F(1) hybrid sterility.

38 eptible to perturbations that result in male sterility.

39 p5-1 results in both male and female partial sterility.

40 reduction of its levels correlates with male sterility.

41 a catalytically inactive DUB does not induce sterility.

42 , almost all infections resulted in complete sterility.

43 owth retardation, cancer predisposition, and sterility.

44 ar bridges in all germ cells and causes male sterility.

45 pollen production and results in plant male sterility.

46 id onset of severe developmental defects and sterility.

47 ent incompatibilities that cause hybrid male sterility.

48 ephalopathy in multiple brain areas and male sterility.

49 ion and subsequently collapsed, causing male sterility.

50 contribute about equally to HMS1 hybrid male sterility.

51 he developing ovary, leading to adult female sterility.

52 One of the most common HIs is male sterility.

53 radictory observations exist for hybrid male sterility.

54 iple TE families, gametogenesis defects, and sterility.

55 evolution, and to characterize hybrid anther sterility.

56 xhibit defective spermatogenesis and/or male sterility.

57 mice leads to acephalic spermatozoa and male sterility.

58 wer development, delayed flowering, and male sterility.

59 velopmental defects, including lethality and sterility.

60 ibits homologous pairing defects, leading to sterility.

61 os-2; xnd-1 double mutants display synthetic sterility.

62 m of the transcriptional activator MS1 (MALE STERILITY 1), which contains a PHD domain associated wit

63 crobial activity cause this increased lesion sterility; 3) IL-10 produced by activated macrophages is

64 processes, including immunity, cancer, male sterility, adaptive evolution, and non-Mendelian inherit

65 haracteristic of an essential zona ligand is sterility after genetic ablation.

66 idermidis and S. aureus strains and maintain sterility after removal of cefazolin.

67 or several times, of recessive and dominant sterility alleles acting in her offspring.

68 s carries any autosomal dominant hybrid male sterility alleles: reciprocal F(1) hybrid males are perf

69 elopment, radiation doses required to ensure sterility also destroy immunogenic protein epitopes need

70 related populations isolated by hybrid male sterility also show fixation of alternative neo-Y haplot

71 siliques with fewer ovules, pollen and seed sterility, altered Megaspore Mother Cell (MMC) specifica

72 o cleave in a gene associated with Anopheles sterility and another to cleave near a mutation that cau

73 plex with the CSR-1 Argonaute protein causes sterility and defects in chromosome segregation in early

74 ong association between X-linked hybrid male sterility and disruption of MSCI and suggest that trans-

75 tent with mammalian models, causes increased sterility and embryonic lethality.

76 KEY MESSAGE: We have developed a unique male-sterility and fertility-restoration system in rice by co

77 nd goblet cell metaplasia to preserve airway sterility and homeostasis.

78 rent possibility-the genes that cause hybrid sterility and lethality often come to differ between spe

79 olution and genetics of interspecific hybrid sterility and lethality were once also thought to evolve

80 tibilities in interspecific hybrids, such as sterility and lethality, are widely observed causes of r

81 and to show that the insertion leads to male sterility and male mating behavior defects that include

82 male sterility factors, we found no QTL for sterility and multiple QTL for hybrid viability (indicat

83 asis of association between cytonuclear male sterility and other floral traits in Mimulus hybrids.

84 leading to blockade of embryogenesis, adult sterility and premature death 18-24 months post-treatmen

85 Seed sterility and reduced transmission frequency of the muta

86 The genetic bases of hybrid sterility and segregation distortion are at least partia

87 genetic architecture underlying hybrid male sterility and segregation distortion between the Bogota

88 e necessary but not sufficient for both male sterility and segregation distortion in F(1) hybrids bet

89 germline, when strongly expressed they cause sterility and severe actin defects including cortical ac

90 e-induced harm are sperm cells, which induce sterility and shorten lifespan by displacing conspecific

91 n species divergence, relative to behavioral sterility and spermatogenic infertility.

92 e plants greatly alleviates the dwarfism and sterility and substantially reverses the biochemical phe

93 complex genetic architecture for hybrid male sterility and suggest a prominent role for reproductive

94 and that stau-1;eri-1 double mutants exhibit sterility and synthetic germ line defects.

95 ctive root growth, loss of apical dominance, sterility, and homeotic floral transformations.

96 dies of F2 hybrid inviability and behavioral sterility, and indicate that Wolbachia-induced hybrid in

97 ent from most described cases of hybrid male sterility, and may represent an earlier stage of hybrid

98 Loss of EMF2B in rice results in complete sterility, and mutant flowers have severe floral organ d

99 tasks to maintain intracellular homeostasis, sterility, and organellar and cellular functionality.

100 plantation is associated with a high risk of sterility, and some patients are offered fertility prese

101 olecular and functional basis of hybrid male sterility, and strongly reinforce the role of DNA-bindin

102 Hybrid anther sterility appeared parallel at the molecular level to pr

103 Therefore, although F1 male sterility appears to be caused mainly by X-autosome inco

104 Sterility appears to be primarily due to elimination of

105 Boys faced with future sterility as a result of the need of a sterilizing cance

106 , several PRDM9 SNPs have been implicated in sterility as well.

107 at knockdown of Gld2 transcripts causes male sterility, as GLD2-deficient males do not produce mature

108 Rbp9 misregulation is central to su(Hw)(-/-) sterility, as Rbp9(+/-), su(Hw)(-/-) females are fertile

109 es largely normal behavior but severe female sterility associated with ectopic lov expression in the

110 of these genes and demonstrated age-related sterility associated with impaired meiosis and germ cell

111 ing experimental crosses, and assess whether sterility barriers are related to intraspecific changes

112 ion of mouse that results in male and female sterility because of defects in gametogenesis.

113 generation (backcross and F(2)) hybrid male sterility between D. virilis and D. americana is not pol

114 some has only a modest effect on hybrid male sterility between D. virilis and D. americana.

115 Incomplete hybrid sterility between the two species generates selection fo

116 , I examine the genetic basis of hybrid male sterility between two species of Drosophila, Drosophila

117 cot rice (Oryza sativa) causes complete male sterility, but not in the dicot model Arabidopsis (Arabi

118 segregating for the restorer region and male sterility, but with unique flanking introgressions.

119 e also evaluated the role of Prdm9 in hybrid sterility by assessing allelic differences of ZF domains

120 nts revealed that the slcer6 mutant has male sterility caused by (1) hampered pollen dispersal and (2

121 bit the meiotic arrest, DNA damage, and male sterility characteristic of mice lacking piRNAs.

122 ception mutants is profound sporophytic male sterility characterized by failure of stamen filament el

123 Hybrid behavioral sterility, characterized by a reduced ability of hybrids

124 -92 mitochondria that cause cytoplasmic male sterility (CMS) by homeotic transformation of the stamen

125 asexual continuum, whether cytoplasmic male sterility (CMS) facilitates the evolution of paternal le

126 sex determination involves cytoplasmic male sterility (CMS) genes and nuclear restorers of male fert

127 ial-encoded genes can cause cytoplasmic male sterility (CMS), resulting in the coexistence of female

128 abortion, which is known as cytoplasmic male sterility (CMS).

129 In addition to embryo death and male sterility, conditional psp1 mutants displayed a short-ro

130 clear incompatibilities caused hybrid anther sterility, confounding estimation of reproductive organ

131 nds can fully rescue COII(G177S) -associated sterility, consistent with previously proposed models th

132 cells were isolated from mice housed in low sterility "conventional" (CV) facilities and not from mi

133 de1c or a pan-neuronal promoter, whereas the sterility could be only partially rescued by expression

134 tolerance to cold- and heat-induced spikelet sterility could provide benefits similar to those obtain

135 e knockout mutants suffer from a strong male sterility defect as a consequence of pollen tubes that f

136 d alternative splicing that could rescue the sterility defect of glc.

137 c, and rad23d) or induce mild phyllotaxy and sterility defects (rad23b), higher-order mutant combinat

138 wever, did not rescue conditional growth and sterility defects of scd1-1.

139 ells of beta-TrCP1 knockout mice resulted in sterility due to a lack of mature sperm.

140 d cell-wall properties, and resulted in male sterility due to complete disruption of formation of the

141 ts, while Loxl2 overexpression triggers male sterility due to epididymal dysfunction caused by epithe

142 cial traits caused undesirable branching and sterility due to epistasis, which breeders overcame with

143 nd ODA defects, proprioception deficits, and sterility due to immotile sperm.

144 elongated life span and flowering duration, sterility, dwarfing, reduced seed yield and shorter root

145 ination region and included a candidate male sterility factor and additional genes with sex-specific

146 d models often find an excess of hybrid male sterility factors, we found no QTL for sterility and mul

147 lts clearly suggest that the customized male-sterility & fertility-restoration system can be exploite

148 accessions and likely accounts for the semi-sterility found in some G. soja by G. max crosses.

149 at the highest risk of developing permanent sterility from cancer treatment.

150 rict outcrossing using the ms1b nuclear male sterility gene.

151 and may affect selection on cytoplasmic male sterility genes when they initially arise.

152 pecies to be especially dense in male hybrid sterility genes.

153 double mutants have a synergistic effect on sterility, H3K4me2, and spermatogenesis expression.

154 In diverse crop plants, male-sterility has been exploited as a useful approach for pr

155 nothricin (5 mg/l), confirming that the male sterility has been successfully engineered in rice.

156 sion in the alveoli, and maintenance of near sterility have been accommodated by the evolution of a m

157 productive barrier in house mice-hybrid male sterility-have been restricted to a single subspecies pa

158 egulatory pathways may result in hybrid male sterility (HMS) when dominance and epistatic interaction

159 other symptoms by radiosensitivity, cancer, sterility, immunodeficiency and neurological defects.

160 culus domesticus Y chromosome to hybrid male sterility in a cross between wild-derived strains in whi

161 Transgenes containing either locus rescue sterility in about one-half of the males, and among fert

162 use mutants exhibit a failure in meiosis and sterility in both sexes.

163 arly meiosis and whose deficiency results in sterility in both sexes.

164 g partners, and loss of this activity causes sterility in Drosophila.

165 nther development pathways shows that anther sterility in females probably occurs through interruptio

166 rare exception to Haldane's rule for female sterility in field cricket sister species (Teleogryllus

167 tant clues about the genetics of hybrid male sterility in house mice, they have been restricted to F1

168 Previous work has shown that male sterility in hybrids between Mimulus guttatus and Mimulu

169 e development, eventually causing widespread sterility in its inflorescences, the tassel and the ear.

170 F) domains, have been associated with hybrid sterility in male house mice via spermatogenic failure a

171 g Geminin from spermatogonia causes complete sterility in male mice.

172 -p63E results specifically in meiotic arrest sterility in males.

173 The mule, a classic example of hybrid sterility in mammals also exhibits a similar spermatogen

174 Disruption of the PRDM9 gene results in sterility in mice.

175 report that Setd1b deficiency causes female sterility in mice.

176 ed to decline in aging mother cells, causing sterility in old cells.

177 Sterility in the absence of P granules is often accompan

178 e CMS cytotypes has been sequenced, and male sterility in the cms-S and cms-T cytotypes is linked to

179 ssion of SEC31A rescued the conditional male sterility in the double mutant.

180 Hybrid sterility in the heterogametic sex is a common feature o

181 The conditional male sterility in the mutant is a sporophytic trait, and when

182 e II detoxification enzymes led to increased sterility in the presence of dietary DGLA.

183 the Ms2 gene and show that Ms2 confers male sterility in wheat, barley and Brachypodium.

184 Sterility in xnd-1 mutants is correlated with an increas

185 ed QTL that underlie measures of hybrid male sterility, including testis weight, sperm density, and s

186 sterile rpa1a with rpa1c results in complete sterility, incomplete synapsis and meiotic chromosome fr

187 ET-2/SETDB1 also show functionally redundant sterility, increased germline apoptosis, DNA repair defe

188 ion in RPL27a function results in increasing sterility, indicating a dose-dependent relationship betw

189 Inactivation of RNAi suppresses sterility, indicating that aberrant siRNAs produced in t

190 -laid eggs is in fact the same as one of the sterility-inducing queen signals that we identified earl

191 I find that hybrid sterility involves a single hybrid incompatibility of at

192 rding to the Dobzhansky-Muller model, hybrid sterility is a consequence of the independent evolution

193 Male sterility is a valuable trait for plant breeding and hyb

194 er alleles on Linkage Group 7, and that male sterility is associated with reduced corolla size.

195 culus musculus and M. m. domesticus in which sterility is asymmetric: F1 males with a M. m. musculus

196 in a population of hermaphrodites where male sterility is caused by a dominant allele in a nuclear ge

197 ction in cell size and fewer cells, and male sterility is caused by loss of the pollen coat and prema

198 It is not known, however, whether F1 male sterility is caused by X-Y or X-autosome incompatibiliti

199 Indeed, male sterility is common among aneuploid mice used to study c

200 cular interest in plants as cytoplasmic male sterility is controlled by mitochondrial genotypes, some

201 Male sterility is dominant in both the parental species and t

202 in selection, in which a gene for altruistic sterility is favored when the altruism sufficiently bene

203 ve barriers that can isolate species, hybrid sterility is frequently due to dysfunctional interaction

204 usculus musculus X chromosome to hybrid male sterility is large.

205 We propose that sterility is mediated by the production of toxic DGLA-de

206 nal basis of genetic factors for hybrid male sterility is of great interest.

207 Hybrid sterility is one of the earliest postzygotic isolating m

208 rating that the genetic basis of hybrid male sterility largely differs between these closely related

209 al16Gly) missense change rescued mutant male sterility less than the wild-type did.

210 Hybrid incompatibility (including sterility, lethality, and less extreme negative effects)

211 Laboratory crosses have identified sterility loci, but each encompasses hundreds of genes.

212 We identify complex interactions among sterility loci, suggesting multiple, non-independent gen

213 the perspectives of disease transmission and sterility maintenance, the world's blood supplies are ge

214 ice lacking either gene exhibit sex-specific sterility, making these proteins promising non-hormonal

215 t a universal mechanistic basis of F1 hybrid sterility manifested by pachytene arrest.

216 ch should be solved for the investigation of sterility mechanism in wide hybridization of plants.

217 Despite predictions of the classic, hybrid-sterility model of chromosomal speciation, some organism

218 ombination-suppression model over the hybrid-sterility model of chromosome speciation are the most co

219 dual pattern is inconsistent with the hybrid-sterility model which, due to association of major chrom

220 s transition, some involving male and female sterility mutations linked in a region of suppressed rec

221 vent both meiotic catastrophe and the female sterility observed in mtrm/mtrm females.

222 ACA12 rescues the phenotype of partial male sterility of a null mutant of the plasma membrane isofor

223 are phenotypically critical targets, because sterility of Deltamir mutants was substantially rescued

224 zygotic isolation is now complete because of sterility of F1 hybrid progeny, prezygotic isolation is

225 ed MSCI might contribute to the preferential sterility of heterogametic hybrid males.

226 by antibiotic treatment or by changes in the sterility of housing conditions reduces the number and f

227 such as the failure to form hybrid seeds or sterility of hybrid offspring, are often less strong tha

228 Thus, the sterility of Rnf17 mutants may be a manifestation of a s

229 o pretreat the skin in order to maintain the sterility of sample collection.

230 The complete sterility of surviving F(1) hybrids frustrated Sturtevan

231 mucus clearance, which is needed to maintain sterility of the lung.

232 hat it is involved in innate immunity and/or sterility of the mucosa.

233 Microbial quality and sterility of the samples were analysed following 15, 30,

234 The sterility of these mutant females was caused by an ovula

235 To circumvent the sterility of this hybrid strain, we developed a novel me

236 CG14620 transgene rescued deafness and male sterility of tilB mutants.

237 Transgenic Os07g37920-OE lines showed no sterility or anther dehiscence problems.

238 he relative frequencies of mutations to male sterility or in the frequencies of genes with male-speci

239 house mice, they have been restricted to F1 sterility or incompatibilities involving the X chromosom

240 ion of reproductive barriers, such as hybrid sterility or inviability between populations.

241 While individual genes that cause hybrid sterility or inviability have been identified in a few c

242 ements and result in reduced male fertility, sterility or inviability.

243 genetic background of one species can cause sterility or lethality in the genetic background of anot

244 eproductive incompatibilities such as hybrid sterility or lethality?

245 te beneficial phenotypes such as conditional sterility or pathogen resistance.

246 smic F-actin structures well without causing sterility or striking actin defects.

247 leads to severe testicular atrophy and male sterility owing to rapid depletion of both SCs and germ

248 In a model of transient sterility, p53 was required for the recovery of fertilit

249 ast majority of germ cells and can result in sterility, PAX7+ spermatogonia selectively survived, and

250 risingly, mutation of At-FANCM overcomes the sterility phenotype of an At-MutS homolog4 mutant by app

251 d AGAP007280) that confer a recessive female-sterility phenotype upon disruption, and inserted into e

252 down of cyp-33E2 suppressed the DGLA-induced sterility phenotype.

253 with both overexpression and the severity of sterility phenotypes in hybrids.

254 n gene yet identified and is responsible for sterility phenotypes in male hybrids of certain mouse su

255 on (PAR) was strongly associated with hybrid sterility phenotypes when heterozygous.

256 d QTL associated with a range of hybrid male sterility phenotypes, including testis weight, sperm den

257 genes involved in lipid homeostasis enhanced sterility phenotypes, while mutations reducing the activ

258 ved insulin/IGF signaling pathway suppressed sterility phenotypes.

259 Male sterility plays an important role in F1 hybrid seed prod

260 n early PGCs causes complete male and female sterility, preceded by the upregulation of LINE1 and IAP

261 Loss of Capu leads to female sterility, presumably because polarity determinants fail

262 ster-than-linear accumulation of hybrid seed sterility QTL, thus empirically evaluating and confirmin

263 l species, however, the map location of male sterility reflected the maternal donor in one cross, but

264 lution mapping of loci contributing to these sterility-related phenotypes.

265 with its excellent forward genetics and male sterility screens, was used to identify >50 meiotic muta

266 ar defects as pink1 and parkin mutants: male sterility, shortened lifespan, and reduced climbing abil

267 , loci underlying traits unrelated to hybrid sterility show no evidence for an accelerating rate of a

268 ping of two crosses showed dominance of male sterility similar to the parental species, however, the

269 in Arabidopsis resulted in conditional male sterility, since pollen coat lipids are responsible for

270 Skeletal fusions with sterility (sks) is an autosomal recessive mutation of mo

271 dites to show a male germline-dependent self-sterility, so we have named it spe-45.

272 allenged by physicochemical characteristics, sterility/sterilization issues, safety and efficacy.

273 P3-2 only affected the stamens, resulting in sterility, stunting or weak transformation towards carpe

274 differentiation of all prospermatogonia and sterility, suggesting that there is a crucial role for t

275 s thus escape silencing and trigger a hybrid sterility syndrome termed P-M hybrid dysgenesis.

276 n has been used to develop a reversible male sterility system applicable to hybrid crop production.

277 Here the first reproductive sterility system for the tephritid fruit fly pest, Anast

278 entified breaches in mixing, filtration, and sterility testing practices.

279 expression, karyotype analysis, and pathogen/sterility testing was conducted in selected ES cell line

280 X Chromosome is more likely to produce male sterility than on autosome (so-called large-X theory); s

281 ation of Sin3A in the male germline leads to sterility that results from the early and penetrant apop

282 nsense germline variant associated with male sterility that results in loss of NLRP14 function and hy

283 For engineering nuclear male sterility, the coding region of Brassica napus cysteine

284 lacental abruption, fetal demise, and female sterility, thereby placing BMPR2 at a central point in t

285 sive recombination, tentatively linking male sterility to orf293, a mitochondrial gene causing homeot

286 tion in oocytes, both defects that result in sterility, to fertile animals with significantly reduced

287 the autosomal loci were unique to a specific sterility trait and exhibited an effect only when homozy

288 Under these conditions, 100% induced sterility was achieved even when the total immersion tim

289 The contribution of each gene to hybrid male sterility was assessed by means of germ-line transformat

290 Mutual gametophytic sterility was overcome by complementation with a genomic

291 Radiochemical purity and sterility were examined.

292 ch results in virtually complete hybrid male sterility when homozygous in the genetic background of s

293 in somatic gonadal cells resulted in female sterility, whereas males were fully fertile.

294 s in RPL27aC result in high levels of female sterility, whereas mutations in RPL27aB have a significa

295 hia bacteria can cause a form of conditional sterility, which can provide an alternative to genetic m

296 N-nitrosourea-induced mutagenesis that shows sterility with germ cell depletion caused by defective p

297 learance balances rapid restoration of blood sterility with induction of specific antibacterial immun

298 UP107 (p.D447N), resulted in almost complete sterility, with a marked reduction in progeny, morpholog

299 er removal of nos-1 leads to almost complete sterility, with the vast majority of animals without ger

300 of the hybrid reflects the location of male sterility within the maternal donor species and (3) cros