ライフサイエンスコーパス: steroid hormone

1 s, with progesterone being the most abundant steroid hormone.

2 drosterone, an important naturally occurring steroid hormone.

3 osis that follows the administration of this steroid hormone.

4 ine production, carbohydrate metabolism, and steroid hormones.

5 cholesterol, a key step in the generation of steroid hormones.

6 and constrained with productions of selected steroid hormones.

7 uronidated estrogen, testosterone, and other steroid hormones.

8 ysiological role in transport and balance of steroid hormones.

9 is is not likely regulated directly by these steroid hormones.

10 l (CH) to pregnenolone, the precursor to all steroid hormones.

11 ly maintained by the presence of circulating steroid hormones.

12 een observed and attributed to the action of steroid hormones.

13 therapeutics as well as endobiotics such as steroid hormones.

14 ition, and seasonal cues, as well as gonadal steroid hormones.

15 s and makes them responsive to activation by steroid hormones.

16 utcomes seen during life stages with low sex steroid hormones.

17 sion, differentiation, and responsiveness to steroid hormones.

18 nolone, the first 21-carbon precursor of all steroid hormones.

19 ons and understanding of brain modulation by steroid hormones.

20 -disrupting compounds such as pesticides and steroid hormones.

21 receptors to provide the full impact of all steroid hormones.

22 The current study examined whether the steroid hormone, 17beta-estradiol (E2) can exert long-la

23 is regulated by the interaction between the steroid hormone 20-hydroxy-ecdysone (20E) transferred by

24 yo to bacterial infections and find that the steroid hormone 20-hydroxyecdysone (20-HE) can regulate

25 In this study, we show that the Drosophila steroid hormone 20-hydroxyecdysone (20E) and its nuclear

26 re, we demonstrate a key requirement for the steroid hormone 20-hydroxyecdysone (20E) in the maintena

27 Here we show that the male-transferred steroid hormone 20-hydroxyecdysone (20E) is a key regula

28 is requires a surge in the production of the steroid hormone 20-hydroxyecdysone from the prothoracic

29 Steroid hormones act in the adult brain to regulate gene

30 In order to better understand where sex steroid hormones act to regulate social behavior in this

31 In contrast, a subset of steroid hormones acted as competitive inhibitors of C. d

32 A currently obscure area of steroid hormone action is where the component factors, i

33 roved our understanding of the mechanisms of steroid hormone action on bone and how physiologic, path

34 sed on a validated chemical kinetic model of steroid hormone action, is now used to identify two new

35 Our results provide a genomic map of steroid hormone actions in plants that reveals a regulat

36 The steroid hormone-activated glucocorticoid receptor (GR) r

37 The glucocorticoid receptor (GR) is a steroid-hormone-activated transcription factor that modu

38 differences in the serum levels of hexoses, steroid hormones, acylcarnitines, purine, heme, bile aci

39 at constitutively produce the salt-retaining steroid hormone aldosterone and cause millions of cases

40 pharmaceuticals, personal care products, and steroid hormones, all at ng/L levels in surface and drin

41 Cholesterol is responsible for synthesis of steroid hormones and bile acids, which have been recogni

42 Our results show that both steroid hormones and bile salts are able to increase C.

43 vidence suggests that the actions of ovarian steroid hormones and brain-derived neurotrophic factor (

44 We observed no association between steroid hormones and ER(+)/PR(+) disease.

45 urally similar to cholesterol-derived animal steroid hormones and insect ecdysteroids, with no known

46 he occurrence of 16 endogenous and synthetic steroid hormones and metabolites was evaluated in runoff

47 d treated wastewater effluent to the load of steroid hormones and other wastewater micropollutants (W

48 , transformation, and attenuation of natural steroid hormones and phytoestrogens and estrogenic activ

49 tween high concentrations of early pregnancy steroid hormones and risk of ER(-)/PR(-) breast cancer i

50 ally <5%; however, rates were higher for the steroid hormones and some of the more challenging compou

51 Steroid hormones and their nuclear receptors drive devel

52 nto sex-specific differences in lipid, drug, steroid hormone, and xenobiotic metabolism, with distinc

53 n-like growth factor-1, leptin, adiponectin, steroid hormones, and cytokines.

54 , it is becoming increasingly clear that sex steroid hormones, and in particular the principle female

55 ndicate that the transformation processes of steroid hormone are stereoselective in sediment and co-o

56 Steroid hormones are a large family of cholesterol deriv

57 two of the most commonly observed androgenic steroid hormones are androstenedione (AD) and testostero

58 Bile salts and steroid hormones are biosynthesized from cholesterol, su

59 or ionization and localized ion suppression, steroid hormones are difficult to detect.

60 Steroid hormones are essential for carbohydrate metaboli

61 Female steroid hormones are hypothesized to play a protective r

62 recombinant follicle-stimulating hormone and steroid hormones are ineffective.

63 Several endocrine factors, including sex-steroid hormones are known to influence adiponectin secr

64 s in endogenous postmenopausal levels of sex steroid hormones are not substantially related to these

65 Because steroid hormones are often conjugated to glucuronic acid

66 ession of endocrine related-cancers in which steroid hormones are powerful mitogenic agents.

67 Steroid hormones are produced throughout the phylogeneti

68 Supplements and growth promotants containing steroid hormones are routinely administered to beef catt

69 lts indicate that short-term treatments with steroid hormones are sufficient to alter both Lep transc

70 Circulating gonadal steroid hormones are thought to modulate a wide range of

71 Sexual transfer of this steroid hormone as part of a mating plug dramatically ch

72 duction during infusion of deuterium-labeled steroid hormones as tracers; plasma clearance of 100 mg

73 rosterone sulfate (DHEA-S), a small-molecule steroid hormone, as the target analyte.

74 -ATPase is activated by ouabain, a mammalian steroid hormone, at far lower concentrations than those

75 ber intake, which has been shown to decrease steroid hormone bioavailability (decreased blood concent

76 ssion profiles showed that genes involved in steroid hormone biosynthesis (Star, Cyp11a1, and Hsd3b1)

77 ute the dogma that TSPO is indispensable for steroid hormone biosynthesis and viability.

78 sphingolipids have been shown to control the steroid hormone biosynthesis in adrenal glands, indicati

79 Human steroid hormone biosynthesis is the result of a complex

80 hondrial membrane, the rate-limiting step in steroid hormone biosynthesis.

81 gatively regulates accumulation of the plant steroid hormone brassinosteroid (BR) in organ boundaries

82 Plant steroid hormones, brassinosteroids (BRs), play essential

83 Plant steroid hormones, brassinosteroids (BRs), play essential

84 The plant steroid hormones, brassinosteroids (BRs), play important

85 Plant steroid hormones, brassinosteroids (BRs), play important

86 l plasticity is linked to the actions of sex steroid hormones, but the precise mechanisms are unclear

87 H4IIE-luc bioassay, effects on production of steroid hormones by use of the H295R steroidogenesis ass

88 actors, but it has long been recognised that steroid hormones can exert powerful modulatory effects a

89 This study demonstrates that steroid hormones can help reestablish functional neurona

90 Our data imply that steroid hormones can shift the immunological balance in

91 en that Chst10 transfers sulfates to several steroid hormones, Chst10 likely functions in widespread

92 rrelations between urinary BPA and serum sex steroid hormone concentrations in adults.

93 Because BDNF and gonadal steroid hormones conjointly influence neuronal growth, s

94 symptoms (LUTS), and it is not clear how sex steroid hormones contribute to the rates of change in th

95 Steroid hormones control important developmental process

96 ssion profiles, these findings indicate that steroid hormone-coupled control of let-7-C microRNAs is

97 of neuroblast proliferation/quiescence and a steroid hormone cue that is required for temporal transc

98 The steroid hormone dafachronic acid (DA) directs developmen

99 ce, we used gonadectomy to eliminate gonadal steroid hormone-dependent expression of AVP in the BNST

100 tor complex plays a key coregulatory role in steroid hormone-dependent transcription and is chiefly t

101 The phenotype depends on sex-steroid hormones: dihydrotestosterone treatment of gonad

102 be mediated by organizational actions of sex steroid hormones during development.

103 nd songbirds is linked to the actions of sex steroid hormones during ontogeny but also in adulthood i

104 The steroid hormone ecdysone and its receptor (EcR) play cri

105 In Drosophila, the steroid hormone ecdysone controls developmental transiti

106 Here, we show that the steroid hormone ecdysone controls the expression of the

107 morphosis of insects, in which pulses of the steroid hormone ecdysone drive the wholesale transformat

108 We show that the steroid hormone ecdysone functions in Drosophila to cont

109 that in Drosophila, endocrine release of the steroid hormone ecdysone is mediated through a regulated

110 The steroid hormone ecdysone is the central regulator of ins

111 Previous research suggested that the steroid hormone ecdysone may play a role in this polyphe

112 Sequential pulses of the steroid hormone ecdysone regulate the major developmenta

113 anscription factors following a pulse of the steroid hormone ecdysone such that different times in wi

114 regulated in a cell-autonomous manner by the steroid hormone ecdysone, through changes in expression

115 ning by local degeneration controlled by the steroid hormone ecdysone.

116 y the level and duration of secretion of the steroid hormone ecdysone.

117 europeptide that promotes the release of the steroid hormone ecdysone.

118 ogenic differentiation when treated with the steroid hormone ecdysone.

119 ormation processes do not necessarily reduce steroid hormone ecotoxicity.

120 The sex-steroid hormone estradiol (E2) enhances the psychoactive

121 The steroid hormone estrogen is important for brain function

122 lpha4 subunits, which is also a PAM site for steroid hormone estrogens such as 17beta-estradiol.

123 Free and conjugated steroid hormones (estrogens, androgens, and progesterone

124 Progesterone (P4) is a natural steroid hormone excreted by humans and animals.

125 some DNA methylation patterns are altered by steroid hormone exposure in the developing brain, less i

126 e (LH) pulse frequency, implicating abnormal steroid hormone feedback to gonadotropin-releasing hormo

127 and estradiol in the mechanisms by which sex-steroid hormone fluctuations provoke depressive symptoms

128 explore these phenomena for endocrine-active steroid hormones, focusing on examples of conserved bioa

129 d BR signalling network and explain how this steroid hormone functions as a master regulator of plant

130 pressed glucocorticoid receptors (GRs), this steroid hormone has pleiotropic effects on many cell typ

131 Throughout the animal kingdom, steroid hormones have been implicated in the defense aga

132 tanding of cellular and molecular actions of steroid hormones have gone beyond the important cell nuc

133 ole in the regulation of systemic energy and steroid hormone homeostasis.

134 Altered concentrations of sex steroid hormones, impaired reproductive performance, and

135 as the sulfate DHEA-S, is the most abundant steroid hormone in human blood.

136 rone (DHEA) is the most abundant circulating steroid hormone in humans, produced by the adrenals, the

137 Testosterone is a key steroid hormone in the development of male reproductive

138 s glucuronidated steroid hormone to regulate steroid hormone in vivo.

139 neurons are differentially regulated by sex steroid hormones in a dose-dependent manner.

140 elated pathologies are heavily influenced by steroid hormones in a variety of vertebrate species, inc

141 SENSITIVE-1 (BRI1) is the major receptor for steroid hormones in Arabidopsis.

142 particularly suited for selective capture of steroid hormones in biological and environmental samples

143 le and the role of gonadotropins and ovarian steroid hormones in ESR36 expression.

144 sents an analytical method for evaluating 15 steroid hormones in fish tissue.

145 The potential presence of steroid hormones in runoff from sites where biosolids ha

146 Cholesterol is the sole precursor of steroid hormones in the body.

147 of a "window of therapeutic opportunity" for steroid hormones in the brain.

148 and rapid non-genomic actions of circulating steroid hormones in the brain.

149 a new signaling pathway in the regulation of steroid hormones in the uterus, and to overcome P4 resis

150 likely functions in widespread regulation of steroid hormones in vivo.

151 esponsible for tissue resistance to multiple steroid hormones including glucocorticoids observed in a

152 nzymatic process that terminally inactivates steroid hormones, including estrogens and androgens, the

153 The steroid hormone-induced effect on BKCa channels is a tar

154 s of non-pregnant animals, hypoxia inhibited steroid hormone-induced up-regulation of BKCa channel cu

155 factor FoxA occur in embryonic development, steroid hormone induction, and human cancers.

156 ing development, cellular reprogramming, and steroid hormone induction.

157 ted by psychological stress, but cortisol "a steroid hormone" is known as a potential biomarker for i

158 Cortisol, a steroid hormone, is an important biomarker for psycholog

159 fate and bioavailability of progesterone, a steroid hormone known to cause endocrine-disrupting effe

160 These results suggest that both absolute sex steroid hormone levels and the rates at which the levels

161 Pregnancy, parity, and circulating steroid hormone levels are associated with risk of breas

162 method was successfully applied to determine steroid hormone levels in the breast tissue of healthy w

163 ng brain, less is known about how changes in steroid hormone levels influence DNA methylation pattern

164 -based coloration, cellular immune response, steroid hormone levels, and reproduction.

165 cleus HVC in response to seasonal changes in steroid hormone levels, and send long axonal projections

166 ferent between men and women, and female sex steroid hormones likely have a role in this regulation.

167 e a significant contributor to environmental steroid hormone loading from cattle feedyards.

168 tent anti-inflammatory and immunosuppressive steroid hormones, mainly produced by the adrenal glands.

169 genes in the adult brain by the presence of steroid hormones may play a role in the homeostatic regu

170 Steroid hormones mediate critical lineage-specific devel

171 y for implantation is orchestrated by cyclic steroid hormone-mediated signals.

172 e in vivo roles of this protein in lipid and steroid hormone metabolism and the reduction of methemog

173 are essential for bile acid biosynthesis and steroid hormone metabolism.

174 and biochemical mechanisms through which sex-steroid hormones modulate memory, and a specific hypothe

175 The X-linked gene STS encodes the steroid hormone-modulating enzyme steroid sulfatase.

176 up of steroids with structural similarity to steroid hormones of mammals.

177 e literature evaluating the impact of female steroid hormones on cognition, and the putative mechanis

178 iving rise to the idea that the influence of steroid hormones on early fetal brain development may be

179 MSP suggests an indirect paracrine effect of steroid hormones on stem cells via the mature neighborin

180 We propose that trafficking of steroid hormones out of endocrine cells is not always th

181 nt decades has demonstrated that ovarian sex-steroid hormones, particularly 17beta-estradiol (E2), ar

182 we identify a new HSP90 client in the plant steroid hormone pathway: the transcription factor BES1.

183 x 10(-8)), implicating genes involved in sex steroid hormone pathways (FN1, CCDC170, ESR1, SYNE1 and

184 ETS domain transcription factor involved in steroid hormone pathways.

185 In this study, the distribution of steroid hormones, phytoestrogens, and estrogenic activit

186 Glucocorticoid steroid hormones play important roles in many neurophysi

187 Although age, genetics, and sex steroid hormones play prominent roles in the cause of be

188 However, neutral steroid hormones possess poor ionization efficiency in M

189 these data provide the first clues as to how steroid hormones potentially modulate the course of gono

190 Steroid hormones produce adverse effects on biota as wel

191 As steroid hormone production in C. elegans and mammals is

192 selective HDL CE uptake and HDL CE-supported steroid hormone production.

193 ovide the critical second messenger to drive steroid hormone production.

194 The altered steroid hormone profile in obese men may contribute to t

195 The steroid hormone progesterone activates CatSper of human

196 The female steroid hormone progesterone regulates ovulation and sup

197 Steroid hormone progesterone released by cumulus cells s

198 xpression in response to binding its cognate steroid hormone, progesterone.

199 se host factors include leptin, adiponectin, steroid hormones, reactive oxygen species associated wit

200 ogate how DNA recognition diversified in the steroid hormone receptor (SR) family.

201 ding of hAgo2 is analogous to Hsp90-mediated steroid hormone receptor activation.

202 Genes involved in steroid hormone receptor activity and circadian rhythm w

203 aperone and target classes by assaying HSP70/steroid hormone receptor and CDC37/kinase interactions,

204 regated membrane versus nuclear actions of a steroid hormone receptor and demonstrated their in vivo

205 and progesterone receptor (PR) are important steroid hormone receptor biomarkers used to determine pr

206 Best established as components of steroid hormone receptor complexes, it is now clear that

207 GT198 protein has been shown as a steroid hormone receptor coregulator and also as a cruci

208 l-by-cell basis by a specific isoform of the steroid hormone receptor ecdysone receptor-B2, for which

209 Mapping of steroid hormone receptor expression revealed that PNA mi

210 ated through interactions of SMTNL1 with the steroid hormone receptor PR-B.

211 dephosphorylation is required for kinase and steroid hormone receptor release from the chaperone comp

212 In breast and prostate cancers steroid hormone receptor signalling is the principal sti

213 gests a previously unidentified link between steroid hormone receptor signalling pathways and the reg

214 pared within the subgroups defined by cancer steroid hormone receptor status (ER and/or PR positive v

215 ficity of SGTA for additional members of the steroid hormone receptor superfamily and the mechanism b

216 The estrogen receptor (ER) is a steroid hormone receptor that acts as a transcription fa

217 ation between vegetable and fruit intake and steroid hormone receptor-defined breast cancer risk.

218 it intake could be associated with decreased steroid hormone receptor-negative breast cancer risk.

219 ago in the DNA-binding domain of an ancient steroid hormone receptor.

220 Steroid hormone receptors (SHRs) and nuclear receptors (

221 A1 (FOXA1) modulates the transactivation of steroid hormone receptors and thus may influence tumor g

222 Steroid hormone receptors are ligand-dependent transcrip

223 ide polymorphisms (SNP) in genes for the sex-steroid hormone receptors are not strongly associated wi

224 ynthesis are mediated by the membrane-bound, steroid hormone receptors G protein-coupled estrogen rec

225 The identification of lysine acetylation of steroid hormone receptors has previously been based on t

226 ts suggest a new functional paradigm whereby steroid hormone receptors in particular and ID proteins

227 Steroid hormone receptors initiate a genetic program tig

228 on to enhancing or repressing transcription, steroid hormone receptors rapidly transduce kinase activ

229 ction with chromatin is likely shared by all steroid hormone receptors regardless of their capacity t

230 bility of pesticides to interfere with other steroid hormone receptors such as glucocorticoid recepto

231 Thus there exist pools of transmembrane steroid hormone receptors that are efficient signaling m

232 beyond the important cell nuclear actions of steroid hormone receptors to include signaling pathways

233 otein ZNF764 acts as an enhancer for several steroid hormone receptors, and haploinsufficiency of thi

234 vitro activity, high selectivity over other steroid hormone receptors, and significant antidepressan

235 fferent pathways demonstrated alterations in steroid hormone receptors, steroidogenesis enzymes, and

236 Like other steroid hormone receptors, the regulation of target gene

237 sduction, including many kinases and nuclear steroid hormone receptors.

238 mistry, including differential expression of steroid hormone receptors.

239 nes that modulate the signal transduction of steroid hormone receptors.

240 nes that modulate the signal transduction of steroid hormone receptors.

241 vo SMTNL1 selectively binds PR and not other steroid hormone receptors.

242 cals (EDCs) due to their ability to bind sex-steroid hormone receptors.

243 uitin-protein ligase and as a coactivator of steroid hormone receptors.

244 ignaling proteins including many kinases and steroid hormone receptors.

245 or a more comprehensive understanding of how steroid hormones regulate immunity and inflammation, a s

246 Steroid hormones regulate multiple but distinct aspects

247 tial mechanism leading to this dimorphism is steroid hormone regulated synthesis of transcripts encod

248 The brassinosteroid (BR) class of steroid hormones regulates plant development and physiol

249 Therefore, we examined ovarian steroid hormone regulation of GPR64 expression in the mu

250 eful for assessing the environmental risk of steroid hormones released from CAFO wastewater and to be

251 Glucocorticoids (GCs) are steroid hormones released from the adrenal gland in resp

252 adrenalectomy which may obviate the need for steroid hormone replacement in patients with multiple or

253 r immune modulation, reproductive cycle, and steroid hormone responsiveness in mice.

254 The affinity of lipidots for steroid hormone-rich areas is of interest to address dru

255 The steroid hormone signaling axis is thought to play a cent

256 We investigated the role of steroid hormone signaling in the brain on distinct featu

257 ur findings present a convergence of BMP and steroid hormone signaling pathways in the regulation of

258 l effects are mediated through the canonical steroid hormone signaling pathways.

259 beta and dorsal root ganglion cells and link steroid hormone signaling to insulin release and pain pe

260 r specific genes with important roles in sex steroid hormone signalling and function, and offer uniqu

261 ions and are enriched near genes involved in steroid hormone signalling and neural function.

262 molecular links between circadian clocks and steroid hormone signalling, although both are important

263 ity, with low levels of gonadotropic and sex steroid hormones, small testes or ovaries, impaired sper

264 Recent evidence has implicated steroid hormones, specifically estrogens, in the rapid m

265 expressed genes were enriched in response to steroid hormone stimulus and immune system development.

266 In addition to glucocorticoids, other steroid hormones such as estradiol and androgens can als

267 ole in determining the environmental fate of steroid hormones, such as 17beta-estradiol (E2).

268 ces to mitochondria (Mito) for initiation of steroid hormone synthesis.

269 nduce free radical damage, which compromises steroid hormone synthesis.

270 ial transport, cholesterol ester storage and steroid-hormone synthesis.

271 Mitofusin-1 and Mitofusin-2 are required for steroid-hormone synthesis.

272 strate androstenedione, unique among several steroid hormones, targeted TRPA1 in peptidergic primary

273 RPM8 further confirmed direct binding of the steroid hormone, testosterone, to the TRPM8 protein.

274 ndogenous concentrations of estradiol, a sex steroid hormone that is known to influence UL risk.

275 lly transferred 20-hydroxy-ecdysone (20E), a steroid hormone that is produced by the male accessory g

276 -estradiol (E2 or estrogen) is an endogenous steroid hormone that is well known to exert neuroprotect

277 Estradiol (E2) is a steroid hormone that negatively affects muscle growth in

278 Progesterone is a steroid hormone that plays a central role in the female

279 ciated with decreased levels of ecdysone - a steroid hormone that regulates developmental transitions

280 Aldosterone is a steroid hormone that signals through renal mineralocorti

281 Brassinosteroids (BRs) are steroid hormones that are essential for the development

282 Brassinosteroids are plant steroid hormones that control many aspects of plant grow

283 Brassinosteroids (BRs) are steroid hormones that coordinate fundamental development

284 nosteroids (BRs) are a unique class of plant steroid hormones that orchestrate myriad growth and deve

285 Glucocorticoids are endogenous steroid hormones that regulate essential biological func

286 Plant sterols and steroid hormones, the brassinosteroids (BRs), are compou

287 to examine associations between baseline sex steroid hormones, the rate of change in these hormones,

288 fection and disease can result in changes in steroid hormone titers and delayed onset of puberty; how

289 thesized that Chst10 sulfates glucuronidated steroid hormone to regulate steroid hormone in vivo.

290 MTNL1 has a role in mediating the actions of steroid hormones to promote fiber switching in skeletal

291 Here, we explored whether steroid hormones to which human spermatozoa are exposed

292 r, the regulatory elements through which the steroid hormone transcriptional regulation of RET is med

293 Here, we used the cross-sex steroid hormone treatment of transsexuals seeking sex re

294 ucted in which beef cattle were administered steroid hormones via subcutaneous implants and feed addi

295 Transcription regulation by steroid hormones, vitamin derivatives, and metabolites i

296 Significant suppression of multiple adrenal steroid hormones was also seen in treated children (redu

297 Elevated concentrations of the steroid hormones were associated with increased risk of

298 al fluctuations in circulating levels of sex-steroid hormones, which are known to be potent neuromodu

299 Clinical response to glucocorticoids, steroid hormones widely used as pharmaceuticals, varies

300 ferred to clinically as corticosteroids) are steroid hormones with potent anti-inflammatory and immun