1      Analysis of 12 mutants with significant steroid hydroxylase activity showed a lack of positive c

2 nduces the expression of the CYP3A family of steroid hydroxylases and modulates sterol and bile acid

3                                          The steroid hydroxylases CYP17A1 (P450c17, 17-hydroxylase/17

4                                          The steroid hydroxylase CYP3A4 is the most abundant P-450 en

5                                 CYP2C12 is a steroid hydroxylase cytochrome P450 whose female-specifi

6 ol the cAMP responsiveness of each different steroid hydroxylase gene.

7 gulate the expression of the cytochrome P450 steroid hydroxylase genes, key mediators of steroidogene

8 SF-1) regulatory element of cytochrome P-450 steroid hydroxylase genes.

9 nscription factor known to regulate the P450 steroid hydroxylases; however, mechanisms that regulate

10            The identification of a number of steroid hydroxylases in human skin prompted us to invest

11 male mouse liver of certain GH-regulated CYP steroid hydroxylases, suggesting that STAT5 protein hete

12 ure on the genes encoding the adrenocortical steroid hydroxylases via the second messenger, cAMP.

13 C12 encodes a female-specific rat liver P450 steroid hydroxylase whose expression is activated by con

14 (CYP2A2) is an adult male-specific rat liver steroid hydroxylase whose sex-dependent expression is re