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1 ked by TA through the mifepristone-sensitive steroid receptor.
2 ansactivation to a greater extent than other steroid receptors.
3 res of this binding mode are more similar to steroid receptors.
4 spective crystal structures of the ancestral steroid receptors.
5 d -21 proteins as conserved PATs for the sex steroid receptors.
6 ting where conserved aspects exist for other steroid receptors.
7 erones that participate in the activation of steroid receptors.
8 ns that do not require activation of cognate steroid receptors.
9 ermine whether midbrain CART neurons contain steroid receptors.
10 nds and redefine the quaternary structure of steroid receptors.
11 altering the molecular pathways targeted by steroid receptors.
12 translocation and function of classical sex steroid receptors.
13 hway leading to the production of functional steroid receptors.
14 able chromatin residence times for FoxA1 and steroid receptors.
15 of transcription by ligand-activated nuclear steroid receptors.
16 ontal cortex, are densely populated with sex steroid receptors.
17 ct as agonist and/or antagonist of different steroids receptors.
18 discrete shift in ligand specificity in the steroid receptors, a family of biologically essential ho
22 trol nucleus HVC (used as a proper name) and steroid receptor activation within HVC; local coactivati
25 uct of the bi-functional long non-coding RNA steroid receptor activator RNA 1 (SRA1) that is part of
29 a major role for FOXA1 in modulating nuclear steroid receptor activity in breast and prostate cancer,
34 ent with selectivity for the GR versus other steroid receptors and a differentiated gene expression p
36 a now demonstrate the oncogenic potential of steroid receptors and implicate altered AR function and
37 nding domain of Ydj1 directly interacts with steroid receptors and is required for the activity of di
38 e folding of Hsp90-dependent clients such as steroid receptors and many kinases involved in cellular
39 e a mechanism through which ID domain of the steroid receptors and other similar transcription factor
40 sm through which ID activation domain of the steroid receptors and other similar transcription factor
41 eus (PMV) expresses dense collections of sex steroid receptors and receptors for metabolic cues, incl
42 uminal compartments complete with functional steroid receptors and stem/progenitor cells able to reco
43 cted on nNOS and Q78 ataxin-3 but not on the steroid receptors, and Mdm2 did not affect any of the co
44 as a chaperone for receptor protein kinases, steroid receptors, and other intracellular signaling mol
45 ion, we hypothesized that nNOS cells contain steroid receptors, and the testosterone-induced restorat
46 L2 is required for normal gene regulation by steroid receptors, and we show that estrogen receptor be
47 lthough evidence suggests that the classical steroid receptors are capable of mediating many of these
52 AR FXXLF motif region and indirectly through steroid receptor-associated p300 and p160 coactivators.
56 of the H295R steroidogenesis assay, and sex steroid receptor binding activity using the yeast estrog
59 Basal-like "triple negative" cancers lack steroid receptors but are cytokeratin (CK) 5-positive an
60 ase the DNA-binding affinity of PR and other steroid receptors by mechanisms that are not well define
62 besides Met, another member of this family, steroid receptor co-activator (SRC) is required for the
64 uch as p300/CBP-associated factor (PCAF) and steroid receptor co-activator 1 (SRC-1), the full length
65 calreticulin, and caspase 3 and decreases in steroid receptor co-activator 1, Grp78/BiP, and annexin
67 d binding domain (LBD) interactions with the steroid receptor co-activator-1 (SRC-1) peptide, displac
71 ne (JH) receptor, Methoprene-tolerant (Met), steroid receptor coactivator (SRC) and GATAa but not ecd
72 tivators, VDR-interacting protein (DRIP) and steroid receptor coactivator (SRC) at different stages o
73 invasion, and metastasis, including the p160 steroid receptor coactivator (SRC) family composed of SR
74 the bHLH transcription factors studied, the steroid receptor coactivator (SRC) showed the most sever
75 rene-tolerant transcription factor (Met) and steroid receptor coactivator (SRC), would be expressed c
77 lencing mediator for retinoid and thyroid or steroid receptor coactivator (SRC)-1 with RARalpha versu
78 OOH-terminal interaction and are enhanced by steroid receptor coactivator (SRC)-1, whereas the bicalu
79 gamma) regulate bone metabolism, and because steroid receptor coactivator (SRC)-2 (TIF-2) enhances ER
81 ne receptors involves the recruitment of the steroid receptor coactivator (SRC)/p160 coactivator LXXL
82 further dissect the roles of members of the steroid receptor coactivator (SRC)/p160 family in PR-med
83 eam target of progesterone receptor (PR) and steroid receptor coactivator (SRC-1) action in the uteru
85 receptor beta (TRbeta) gene that cannot bind steroid receptor coactivator 1 (SRC-1) and Src-1(-/-) mi
86 y less ability than dexamethasone to trigger steroid receptor coactivator 1 (SRC-1) recruitment and h
87 risk HPV type 16 (HPV16) E7 oncoprotein with steroid receptor coactivator 1 (SRC-1), an essential com
88 eciphered a previously unappreciated role of Steroid receptor coactivator 1 (SRC1) in defining the li
89 iquitination greatly enhanced recruitment of steroid receptor coactivator 1 (SRC1), a coactivator cri
90 ement binding protein binding protein (CBP), steroid receptor coactivator 1 (SRC1), and protein argin
91 TCO-mediated interaction between CAR and the steroid receptor coactivator 1 or the glucocorticoid rec
92 D bound to DAC and the fourth LXXLL motif of steroid receptor coactivator 1 reveals that the GR ligan
93 ated the recruitment of TTF-1, p65, CBP, and steroid receptor coactivator 1 to the TBE region of the
96 of the oncogenic transcriptional coregulator steroid receptor coactivator 2 (SRC-2), also known as NC
97 rs that block the association of TRbeta with steroid receptor coactivator 2 (SRC2), we identified a n
98 ding between VDR and a fluorescently labeled steroid receptor coactivator 2 peptide was applied to di
99 corporated them into a sequence derived from steroid receptor coactivator 2, which interacts with est
104 that ERK3 interacted with and phosphorylated steroid receptor coactivator 3 (SRC-3), an oncogenic pro
105 rect interaction of the liganded TRbeta with steroid receptor coactivator 3 (SRC-3), which recruits p
108 e of an active complex of DNA-bound ERalpha, steroid receptor coactivator 3 (SRC-3/NCOA3), and a seco
109 as a model, we have investigated the role of steroid receptor coactivator 3 (SRC3) in gene activation
110 Here, we report that the ER coactivator steroid receptor coactivator 3 (SRC3) is also a coactiva
112 enced by histone acetylation and require the steroid receptor coactivator 3 (SRC3), which mediates in
113 ctivation of gene expression was enhanced by steroid receptor coactivator 3 coactivator, and required
115 ied in breast cancer 1 (AIB1), also known as steroid receptor coactivator 3 or NCOA3, is a transcript
116 parate assays, both the recruitment of SRC3 (steroid receptor coactivator 3, a transcriptional coacti
119 R function by selectively competing with the steroid receptor coactivator AIB1 but not GRIP1 or SRC1
122 or complex disassembly by methylation of the steroid receptor coactivator family coactivators and p30
123 the most active members inhibit the ERalpha/steroid receptor coactivator interaction with K i's in t
124 s induced by GR signaling, and the important steroid receptor coactivator PELP1 was also found to be
125 (Pol II), estrogen receptor alpha (ERalpha), steroid receptor coactivator proteins (SRC), and acetyla
127 ctivator REGgamma directs degradation of the steroid receptor coactivator SRC-3 by the 20S proteasome
128 ctivator REGgamma directs degradation of the steroid receptor coactivator SRC-3 by the 20S proteasome
131 xes, DRIP (VDR-interacting protein) and SRC (steroid receptor coactivator), during keratinocyte diffe
132 Also, coactivator binding studies with a steroid receptor coactivator-1 (receptor interaction dom
136 o part of the active receptor complex is the steroid receptor coactivator-1 (SRC-1) which interacts w
138 During the decade since the discovery of steroid receptor coactivator-1 (SRC-1), the first authen
139 lpha), which requires co-activators, such as steroid receptor coactivator-1 (SRC-1), to facilitate th
142 r activator RNA 1 (SRA1) that is part of the steroid receptor coactivator-1 acetyltransferase complex
143 e interactions of hCAR with the coactivators steroid receptor coactivator-1 and glucocorticoid recept
144 rinsic activity of p160 coactivators such as steroid receptor coactivator-1 and promoted the interact
145 e nuclear receptor interacting domain of the steroid receptor coactivator-1 as a model for exploring
146 and promoted the interaction between PR and steroid receptor coactivator-1 in a mammalian two-hybrid
147 ene and also remarkably reduces basal MR and steroid receptor coactivator-1 recruitment, unraveling a
148 t insulin facilitated the recruitment of the steroid receptor coactivator-1 to the SREBP-1c promoter.
149 interaction with fatty acid metabolites and steroid receptor coactivator-1 while increasing PPARalph
150 d to spironolactone, finerenone inhibits MR, steroid receptor coactivator-1, and RNA polymerase II bi
151 glucose increased PPARalpha interaction with steroid receptor coactivator-1, DNA binding, and transac
152 to bind the IL-4 promoter in the presence of steroid receptor coactivator-1, indicating that PPARalph
153 gate binding and dissociation of full-length steroid receptor coactivator-1a (SRC1a) from full-length
154 reviously demonstrated the potential role of steroid receptor coactivator-2 (SRC-2) as a co-regulator
155 sly shown that the transcriptional regulator steroid receptor coactivator-2 (SRC-2) controls activati
156 es and in HepG2 cells reduced recruitment of steroid receptor coactivator-2 by RORalpha at an endogen
157 gh-throughput screening to identify SMIs for steroid receptor coactivator-3 (SRC-3 or AIB1), a large
159 Molecular Cell, Yu et al. reported that the steroid receptor coactivator-3 (SRC-3) has a novel cytop
160 ctivator amplified in breast cancer 1 (AIB1)/steroid receptor coactivator-3 (SRC-3) have been shown t
161 ent study aimed to elucidate the role of the steroid receptor coactivator-3 (SRC-3) in thyroid carcin
162 oncogene amplified in breast cancer 1 (AIB1)/steroid receptor coactivator-3 (SRC-3) induces mammary t
168 y also caused a failure in downregulation of steroid receptor coactivator-3 (SRC-3), a potent ERalpha
171 sphorylated alternate-spliced isoform of the steroid receptor coactivator-3 (SRC-3Delta4) bridges EGF
172 d crystallographic studies, we identify that steroid receptor coactivator-3 (SRC3) (also named as amp
173 exes did not readily recruit the coactivator steroid receptor coactivator-3 (SRC3) or ER to the PS2 p
174 ociated with the displacement of ERalpha and steroid receptor coactivator-3 from the target EBRs lead
175 shown that TR recruits the coactivator SRC3 (steroid receptor coactivator-3) and that coactivator rec
176 ceptor-associated coactivator 3 (RAC3)/AIB-1/steroid receptor coactivator-3, a nuclear coregulator an
178 growth pathways on which cancer cells rely, steroid receptor coactivators (SRC-1, SRC-2, and SRC-3)
179 interplay and demonstrated that it requires steroid receptor coactivators (SRC-2, SRC-3) and the med
184 CI, Gao and colleagues present evidence that steroid receptor coactivators 1 and 2 (SRC-1 and SRC-2)
187 in the recruitment of RNA polymerase II and steroid receptor coactivators SRC-2 and SRC-3, and chang
190 160 coactivators to hormone response element-steroid receptor complexes has been difficult to investi
191 e tetratricopeptide repeat proteins found in steroid receptor complexes, and Fkbp51 is an androgen re
197 plasm and nucleus that stabilizes unliganded steroid receptors, controls the catalytic activity of ce
198 GE-A11) is a low-abundance, primate-specific steroid receptor coregulator in normal tissues of the hu
199 oteins, one of which is the primate-specific steroid receptor coregulator melanoma antigen-A11 (MAGE-
200 (20-45 min), p300 is recruited to ERalpha by steroid receptor coregulators (SRCs) for enhancer matura
201 to injury and in methyl-binding proteins and steroid receptor coregulatory proteins are also reported
204 ntradicts the traditional understanding that steroid receptors dimerize in the absence of DNA, it is
205 SL was correlated with the LXR target genes, steroid receptor element-binding protein 1c and ATP bind
207 s simplex viral vector to express a chimeric steroid receptor ("ERGR") which binds glucocorticoids ye
210 these effects are initiated through altered steroid receptor expression; however, the immediate down
211 y structure analysis of other members of the steroid receptor family (estrogen, androgen, and progest
213 cocorticoid receptor (GR) is a member of the steroid receptor family of ligand-activated transcriptio
214 ctionally known phosphorylation sites in the steroid receptor family of transcription factors are loc
215 iously found that the ancestor of the entire steroid receptor family was highly specific for estrogen
218 r, there is compelling evidence for membrane steroid receptors for estrogen in hypothalamic and other
223 ene to study the biological function of this steroid receptor in the epithelial compartment at define
225 set of 62 known NR coregulators and the six steroid receptors in 12 nonoverlapping mouse brain regio
226 or coactivator 3 (SRC-3/AIB1) interacts with steroid receptors in a ligand-dependent manner to activa
227 on to the well-characterized role of the sex steroid receptors in fertility and reproduction, organs
228 (A(max)) in gene induction and repression by steroid receptors in general and glucocorticoid receptor
229 and neuroendocrine secretions, expression of steroid receptors in GnIH-ir nuclei, and GnIH inhibition
233 d PRMT6 interaction occurs through the PRMT6 steroid receptor interaction motif, LXXLL, and the AR ac
235 rring more efficient functioning of this sex steroid receptor is associated with "masculinization" of
237 to have actions via binding to their cognate steroid receptors, it is becoming clearer that steroids
244 ctively, these data provide insight into sex steroid receptor-mediated regulation of androgen-inactiv
245 reported to be a coactivator that regulates steroid receptor-mediated transcription and alternative
246 a dual-functional coregulator that regulates steroid receptor-mediated transcription and alternative
248 ta suggest that CpdA is a unique dual-target steroid receptor modulator that has a high potential for
249 c factors that contribute to the function of steroid receptor modulators, providing valuable insight
250 r research on pregnancy hormones and risk of steroid receptor-negative cancers is needed to further c
251 that tumor growth in nude rats bearing human steroid receptor-negative MCF-7 breast tumors can be sig
255 e normal mammary gland does not occur in the steroid-receptor positive cells but rather in adjacent c
256 e of three evolutionarily diverged ancestral steroid receptor proteins using the Zipping and Assembly
258 c knockout of a long non-coding RNA (lncRNA) steroid receptor RNA activator (SRA) (SRAKO) are resista
259 smic RISC proteins PACT, TRBP, and Dicer are steroid receptor RNA activator (SRA) binding NR coregula
261 d secondary structure of a human lncRNA, the steroid receptor RNA activator (SRA), 0.87 kB in size.
263 p68 (DDX5) and its associated noncoding RNA, steroid receptor RNA activator (SRA), form a complex wit
264 have recently shown that the non-coding RNA, steroid receptor RNA activator (SRA), functions as a tra
266 acterized by exquisite potency and favorable steroid receptor selectivity and pharmacokinetic profile
267 he role of pioneer can be reversed, with the steroid receptors serving to enhance binding of FoxA1.
268 chaperone activity of SNCG on stimulation of steroid receptor signaling in mammary gland and, thus in
272 as emerged as a critical mediator of nuclear steroid receptor signalling, manifest at least in part t
273 ide receptor imaging for 3 receptor systems--steroid receptors, somatostatin receptors, and growth fa
275 ription factor FoxA1 is a global mediator of steroid receptor (SR) action in hormone-dependent cancer
276 FKBP52, FKBP51, Cyp40, and PP5 are found in steroid receptor (SR) complexes, but their receptor-spec
279 olecular requirements for the recognition of steroid receptors (SRs) by the lincRNA growth arrest-spe
281 Because of their interactions with other steroid receptors, steroid-metabolizing enzymes, or othe
283 g extracellular signal-regulated kinases and steroid receptors, suggesting that MVP is likely to be i
285 thyroid hormone receptors are members of the steroid receptor superfamily that interact with their DN
286 well studied in specific regions, brain-wide steroid receptor targets and mediators remain largely un
287 orrelations of mRNA expression levels of six steroid receptors that we provide constitute a rich reso
288 al L/HX7LL motif, selectively present in sex steroid receptors, that causes recruitment of TAB2 as a
289 both the apo- and hormone-bound forms of the steroid receptor to modulate its affinity for ligand, wh
290 oadened the search for and identification of steroid receptors to include nonnuclear sites in synapse
291 ing immunophilins FKBP51 and FKBP52 modulate steroid receptor trafficking and hormone-dependent biolo
292 ts activity of the androgen receptor (AR), a steroid receptor transcription factor required for PCa g
294 fic expression of MAGE-11 results in greater steroid receptor transcriptional activity through direct
296 Lysine acetyltransferases interact with steroid receptors upon binding of an agonist and are rec
298 on by androgens makes it distinct from other steroid receptors, which are typically ubiquitinated and
299 (H100)Trp, converts 1E9 into a high-affinity steroid receptor with a ligand recognition profile simil
300 be identified through spatial correlation of steroid receptors with genome-wide mRNA expression acros
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