コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 nografts, but only rats exhibited suppressed steroidogenesis.
2 1), suggesting a regulatory role of HIF-1 in steroidogenesis.
3 e of leptin in hypoxia-induced disruption of steroidogenesis.
4 important regulatory signals for control of steroidogenesis.
5 representing a new role for translocases in steroidogenesis.
6 -1) is essential for adrenal development and steroidogenesis.
7 h severe skeletal deformities and disordered steroidogenesis.
8 biophysical properties that imply a role in steroidogenesis.
9 at the reptilian brain is capable of de novo steroidogenesis.
10 alyzes the initial and rate-limiting step of steroidogenesis.
11 ies are distinct from its activity to induce steroidogenesis.
12 ACTH, stimulates cAMP production and adrenal steroidogenesis.
13 it is converted to pregnenolone to initiate steroidogenesis.
14 aining adrenocortical function, specifically steroidogenesis.
15 PDE8A is a key regulator of LH signaling and steroidogenesis.
16 KA, inhibited both basal and hormone-induced steroidogenesis.
17 s on mitochondrial cholesterol transport and steroidogenesis.
18 ase in cholesterol efflux and an increase in steroidogenesis.
19 tary pool of cAMP that mediates LH-regulated steroidogenesis.
20 confirming the requirement of SCAP-SREBP2 in steroidogenesis.
21 rol is converted to pregnenolone, initiating steroidogenesis.
22 les in the control of spermatogenesis and/or steroidogenesis.
23 ckout approaches to test the role of SCAP in steroidogenesis.
24 embrane and is a critical regulatory step in steroidogenesis.
25 ment from lipid droplets to mitochondria for steroidogenesis.
26 ons such as the detection of gross errors in steroidogenesis.
27 trus phase of the estrous cycle and aberrant steroidogenesis.
28 steroid hydroxylase genes, key mediators of steroidogenesis.
29 a conserved role in gonadal development and steroidogenesis.
30 insulin sensitivity or to direct effects on steroidogenesis.
31 n (StAR) determines adrenal and gonadal cell steroidogenesis.
32 so its selective modulation of FSH action in steroidogenesis.
33 omegestone and to inhibit the hCG-stimulated steroidogenesis.
34 sis and the 22R-hydroxycholesterol-supported steroidogenesis.
35 By contrast, BMP-15 alone had no effect on steroidogenesis.
36 e involvement of the lipoxygenase pathway in steroidogenesis.
37 nship between AA and cAMP in hormone-induced steroidogenesis.
38 or Kit in Leydig cell differentiation and/or steroidogenesis.
39 are required for trophic hormone-stimulated steroidogenesis.
40 eceptors, plays an important role in gonadal steroidogenesis.
41 ertoire of SF-1-responsive genes involved in steroidogenesis.
42 avage enzyme gene, and consequently, promote steroidogenesis.
43 zyme carries out the first committed step in steroidogenesis.
44 vivo showed features associated with active steroidogenesis.
45 mutations was observed on the stimulation of steroidogenesis.
46 ssential roles in adrenocortical and gonadal steroidogenesis.
47 s lacking the protein retained low levels of steroidogenesis.
48 otein is coordinately regulated with adrenal steroidogenesis.
49 REBP activation and subsequent regulation of steroidogenesis.
50 acids may affect prostaglandin synthesis and steroidogenesis.
51 lular levels of cholesterol, a substrate for steroidogenesis.
52 entral location for initiating mitochondrial steroidogenesis.
53 of a blockade of cholesterol utilization for steroidogenesis.
54 or agonists nor did they cause reductions in steroidogenesis.
55 l adrenal hyperplasia, a disorder of adrenal steroidogenesis.
56 itates the rate-limiting step of aldosterone steroidogenesis.
57 multiple key reactions at the heart of human steroidogenesis.
58 lure to accumulate lipid droplets needed for steroidogenesis.
59 an steroidogenic cell lines had no effect on steroidogenesis.
60 ion, SR-BI-mediated selective CE uptake, and steroidogenesis.
61 ipotency, lipid and glucose homeostasis, and steroidogenesis.
62 arian regulators of follicle development and steroidogenesis.
63 R-BI expression, selective CE transport, and steroidogenesis.
64 us, facilitates cholesterol availability for steroidogenesis.
65 an unfolded state, unable to induce maximal steroidogenesis.
66 n (HDL) cholesteryl ester (CE) transport and steroidogenesis.
67 gamma expression potentiates hormone-induced steroidogenesis.
68 omal recessive metabolic disorder of adrenal steroidogenesis.
69 y AR antagonism in addition to inhibition of steroidogenesis.
70 ate-induced suppression of fetal Leydig cell steroidogenesis.
71 asis for these defects appears to be altered steroidogenesis, a direct result of the lack of HDL-C.
72 ity, POR missense mutations cause disordered steroidogenesis, ambiguous genitalia, and Antley-Bixler
73 nduced allergic responses through effects on steroidogenesis, an essential pathway in T(H)2 different
75 p53-dependent apoptosis and is necessary for steroidogenesis and biogenesis of iron-sulfur clusters.
76 ntifungal azole ketoconazole interferes with steroidogenesis and can cause adrenal insufficiency, flu
77 several cancer cells where it is involved in steroidogenesis and cell proliferation, respectively.
80 similarly by FSH and PKA-CQR are involved in steroidogenesis and differentiation, while transcripts m
81 To examine the definitive role of TSPO in steroidogenesis and embryo development, we generated glo
82 amined the ability of the mutants to promote steroidogenesis and enter the mitochondria of transfecte
83 are adequate for maintenance of Leydig cell steroidogenesis and fertility because of partial functio
84 n (StAR) is required for adrenal and gonadal steroidogenesis and for male sexual differentiation.
87 key role for apoE in the tonic inhibition of steroidogenesis and HPA axis activity and have important
88 amily, plays a key role in the regulation of steroidogenesis and is expressed at high levels in stero
89 A pathway-guided analysis revealed ovarian steroidogenesis and leptin signaling as highly relevant
90 We found that PTTH concomitantly promotes steroidogenesis and light avoidance at the end of larval
91 , although the Gipr is essential for adrenal steroidogenesis and links HF feeding to increased levels
92 ved that exogenous RFRP-3 suppresses gonadal steroidogenesis and mating behavior in NMRs given the op
93 remains unclear because its presumed role in steroidogenesis and mitochondrial permeability transitio
94 vidence for the role of miRNAs in regulating steroidogenesis and novel insights into the molecular me
95 ted safety, pharmacokinetics, and effects on steroidogenesis and prostate-specific antigen (PSA) leve
96 t to show the in vivo requirements of SF1 in steroidogenesis and provides novel data on the cellular
97 need to enter into mitochondria to stimulate steroidogenesis and that residues in the C terminus are
98 helicase could be relevant to the control of steroidogenesis and the paracrine regulation of androgen
99 ription factors may have a role in cutaneous steroidogenesis and thus be involved in hair follicle cy
100 ailability of cholesterol, the substrate for steroidogenesis), and a failure to mount a steroidogenic
101 oteins associated with steroid transport and steroidogenesis, and androgen levels were restored in mu
103 es coordinately regulate its expression with steroidogenesis, and in the liver, where it may particip
104 of other cytochrome P450 enzymes involved in steroidogenesis, and interference can pose a liability i
106 the intracellular messenger for LH action on steroidogenesis, and pharmacological evidence indicates
107 ese results suggest that mVL30 RNA regulates steroidogenesis, and possibly other physiological proces
109 Therefore, Tom22 is a critical regulator of steroidogenesis, and thus, it is essential for mammalian
110 s of CMKLR1 signaling in DHT-induced ovarian steroidogenesis, antral follicles were isolated from wil
113 he regulation of ovarian follicle growth and steroidogenesis are now established, noncanonical WNT si
114 etic defects in adrenal gland development or steroidogenesis) are not born with respiratory insuffici
115 s, such as detoxification of xenobiotics and steroidogenesis, are based on the ability to catalyse th
116 tion of steroid hormones by use of the H295R steroidogenesis assay, and sex steroid receptor binding
117 showed StAR-like activity in a cell culture steroidogenesis assay, indicating cholesterol transfer.
118 tor therapy to be an effective stimulator of steroidogenesis, both PDE8 isozymes and PDE4 need to be
119 nce (MIS) is implicated in the regulation of steroidogenesis, breast and prostate growth, and ovarian
120 ues, where it is coordinately regulated with steroidogenesis by adrenocorticotropic hormone (ACTH), h
122 strate that 14-3-3gamma negatively regulates steroidogenesis by binding to Ser-194 of STAR, thus keep
123 et of conformations likely to modulate human steroidogenesis by CYP17A1, demonstrating that this appr
124 d transiently functions at the initiation of steroidogenesis by delaying maximal steroidogenesis in M
125 tory protein (StAR) plays a critical role in steroidogenesis by enhancing the delivery of substrate c
126 tentiates adrenocorticotropin stimulation of steroidogenesis by increasing cAMP-dependent protein kin
127 rotein (StAR) stimulates adrenal and gonadal steroidogenesis by increasing the influx of cholesterol
128 nt mutant StAR protein that cannot stimulate steroidogenesis by isolated mitochondria did not promote
129 low cAMP levels, thereby suppressing resting steroidogenesis by keeping CEH/HSL inactive and StAR pro
130 StAR (StARD1) induces adrenal and gonadal steroidogenesis by moving cholesterol from the outer mit
132 ole of the CRAC domain of PBR in Leydig cell steroidogenesis by using a transducible peptide composed
133 We tested the ability of MLN64 to stimulate steroidogenesis by using COS-1 cells cotransfected with
136 ) enzyme operates at a key juncture of human steroidogenesis, controlling the levels of mineralocorti
137 inase and serine proteinase inhibitors), and steroidogenesis (CYP21A2 and progesterone receptor).
138 on is dependent upon SF-1, cAMP induction of steroidogenesis does not enhance the responsiveness of a
142 hyperplasia is a family of inborn errors of steroidogenesis, each characterized by a specific enzyme
146 d steroid synthesis, suggesting HSL-mediated steroidogenesis entails enhanced oxysterol production.
147 ed alterations in steroid hormone receptors, steroidogenesis enzymes, and specifically, the circadian
148 significant species-specific differences in steroidogenesis, especially CYP17A1 expression and activ
149 We show that, in 4-month-old PACAP-/- mice, steroidogenesis (evaluated by levels of testosterone, st
151 ry protein (StAR) plays an essential role in steroidogenesis, facilitating delivery of cholesterol to
152 -activated receptor gamma coactivator-1alpha/steroidogenesis factor-1-dependent upregulation of aldos
153 ryo development and led to the alteration of steroidogenesis gene transcripts at nanogram per liter c
157 f GRTH associated with gonadotropin-mediated steroidogenesis has provided insights into a novel negat
159 iduals with an ABS-like phenotype and normal steroidogenesis have FGFR mutations, whereas those with
160 al processes ranging from drug metabolism to steroidogenesis, human microsomal cytochrome P450 enzyme
161 tent with these in vivo data, Wnt4 repressed steroidogenesis in adrenocortical and Leydig cell lines,
164 from IFN-gamma to IL-13 production, linking steroidogenesis in CD8(+) T cells, a nonclassical steroi
165 This dominant negative mutant suppressed steroidogenesis in COS cells expressing the mitochondria
167 hese in vitro systems and blocked LH-induced steroidogenesis in intact follicles primed with pregnant
172 transition in several animal species, alter steroidogenesis in multiple animal models and women, and
173 rane-bound EGF moieties abrogated LH-induced steroidogenesis in ovarian follicles but not MA-10 cells
174 d our model to predict the time evolution of steroidogenesis in response to physiological adrenocorti
176 evelopment and regulates adrenal and gonadal steroidogenesis in the adult, whereas LRH-1 is a critica
177 ranscripts by an shRNA construct potentiates steroidogenesis in the commonly used Y-1 adrenal cell li
178 conserved regulator of gonadotropin-induced steroidogenesis in the gonads, although the mechanisms o
179 und 8, we investigated the role of CaV1.3 on steroidogenesis in the human adrenocortical cell line, H
181 ion of the EGFR kinase prevented EGF-induced steroidogenesis in these in vitro systems and blocked LH
185 AP), a polypeptide that regulates testicular steroidogenesis in vitro, we compared the testicular str
188 ated (i) whether hypoxia can directly affect steroidogenesis independent of pituitary regulation via
189 h exogenous gonadotropins stimulated gonadal steroidogenesis, inducing germ cell maturation in males
190 enefits only a small percentage of patients, steroidogenesis inhibitors, including mitotane, ketocona
191 courtship leks, treated with drugs to block steroidogenesis, injected with (3)H-labeled testosterone
193 ng that the cholesterol substrate needed for steroidogenesis is provided by both de novo synthesis an
195 ilization (hpf), a developmental window when steroidogenesis is unregulated by pituitary influence, r
196 and that reactive oxygen is produced during steroidogenesis itself, we hypothesized that long-term s
200 n the lung and indicate that defective local steroidogenesis may contribute to the pathogenesis of al
203 e hypothesized that long-term suppression of steroidogenesis might inhibit or prevent age-related def
204 s, whereas other higher K(m) PDE(s) modulate steroidogenesis more effectively when cells are fully st
205 important participant in skin pigmentation, steroidogenesis, obesity, energy homeostasis and exocrin
206 gical functions including skin pigmentation, steroidogenesis, obesity, energy homeostasis, and exocri
210 ved from cholesterol through the traditional steroidogenesis pathway initiated by enzyme CYP11A1, and
211 ompassing enzyme deficiencies in the adrenal steroidogenesis pathway that lead to impaired cortisol b
213 13-secreting phenotype through regulation of steroidogenesis, potentially governing asthma susceptibi
214 1, demonstrating HSL-dependent regulation of steroidogenesis predominantly involves LXR signaling.
215 take from HDL as a source of cholesterol for steroidogenesis raised the possibility that SR-BI may pa
216 ) treatment of HPX rats maximally stimulated steroidogenesis rates within 5 min with over 10-fold ele
219 n to lead to defects in bone development and steroidogenesis, resulting in sexual dimorphisms, the se
220 hose with ambiguous genitalia and disordered steroidogenesis should be recognized as having a distinc
222 ggesting CYP17A1 has a key role in prostatic steroidogenesis similar to testis and adrenal roles.
223 interaction, olfactory transduction, ovarian steroidogenesis, steroid biosynthesis and CAMs signaling
224 ture, a morphological change associated with steroidogenesis, suggesting possible involvements of LD
225 cholesterol augmented, PDE inhibitor-induced steroidogenesis, suggesting that the cholesterol substra
226 n of reactive oxygen species, a byproduct of steroidogenesis that induces apoptosis, is down-regulate
227 separate events, an initial genetic loss of steroidogenesis that is dependent on steroidogenic acute
228 -3-3gamma isoform is a negative regulator of steroidogenesis that is hormonally induced and transient
229 regulatory protein and a subsequent loss of steroidogenesis that is independent of the protein due t
231 stingly, although cAMP was always needed for steroidogenesis, the EGFR/MAPK pathway was activated and
232 n intracellular cAMP are known regulators of steroidogenesis, the roles of other signaling pathways i
233 te regulatory protein (STAR) participates in steroidogenesis through the mitochondrial transfer of ch
235 g 8-bromo-cAMP (8-Br-cAMP), which stimulates steroidogenesis, triggers the interaction of 14-3-3gamma
236 ion of PDE8B as a major regulator of adrenal steroidogenesis using a genetically ablated PDE8B mouse
238 or of one or more pools of cAMP that promote steroidogenesis via both short- and long-term mechanisms
239 this paper a stoichiometric model of piscine steroidogenesis was constructed and constrained with pro
240 uring human sex-differentiation and onset of steroidogenesis was evaluated by whole-genome expression
243 a1 mRNA - a key mitochondrial P450 enzyme in steroidogenesis, was stimulated at all doses of UVB irra
244 pheral-type benzodiazepine receptor (PBR) in steroidogenesis, we developed a molecular approach based
245 ic androgen-dependent organs and Leydig cell steroidogenesis were fully restored by administration of
247 hrome P450 17A1, 19A1, and 21A2, critical in steroidogenesis, were similar using our purified, full-l
248 ed SR-BI-mediated selective CE transport and steroidogenesis, which were markedly attenuated by parti
249 ifications further induced 8-Br-cAMP-induced steroidogenesis while reducing lipid storage, suggesting
250 el, this study advances our understanding of steroidogenesis with broad implications in biology and m
251 d by TOR and feedback signaling that couples steroidogenesis with growth and ensures proper maturatio
252 ism that adjusts cholesterol trafficking and steroidogenesis with nutrition and developmental program
253 to initiate and terminate massive levels of steroidogenesis within a few minutes, permitting the rap
256 of TLX1 and that mutations that only impair steroidogenesis, without altering the SF1/SRY transactiv
WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。