ライフサイエンスコーパス: steroidogenic

1 te a variety of molecules depending on local steroidogenic activity and access to UVB.

2 Wild-type StAR increased steroidogenic activity by 7-9-fold compared to mutant R1

3 ur previous findings that the skin possesses steroidogenic activity from progesterone, we now show wi

4 the first direct evidence of elevated fetal steroidogenic activity in autism.

5 ituitary-adrenal axis resulting in increased steroidogenic activity in the adrenal cortex and an elev

6 nt lost all cholesterol binding capacity and steroidogenic activity with isolated mitochondria in vit

7 Steroidogenic acute regulatory (StAR) protein facilitate

8 arotenoid-binding protein (CBP), a member of steroidogenic acute regulatory (StAR) protein family wit

9 f PDE8s and PDE4 increased the expression of steroidogenic acute regulatory (StAR) protein.

10 Steroidogenic acute regulatory (StAR) proteins in steroi

11 gulation of progesterone production, such as steroidogenic acute regulatory factor (Star).

12 xpression of the steroidogenic gene products steroidogenic acute regulatory protein (StAR) and melano

13 The steroidogenic acute regulatory protein (StAR) belongs to

14 The steroidogenic acute regulatory protein (StAR) controls t

15 Steroidogenic acute regulatory protein (StAR) facilitate

16 the same promoter region of the CYP17A1 and steroidogenic acute regulatory protein (StAR) genes.

17 gers the interaction of 14-3-3gamma with the steroidogenic acute regulatory protein (STAR) in the cyt

18 The steroidogenic acute regulatory protein (StAR) is require

19 5alpha-THP with the cholesterol transporters steroidogenic acute regulatory protein (StAR) or translo

20 The steroidogenic acute regulatory protein (StAR) simulates

21 Steroidogenic acute regulatory protein (StAR) stimulates

22 In acute stress or hormonal stimulation, steroidogenic acute regulatory protein (StAR) transports

23 ly, we have shown that overexpression of the steroidogenic acute regulatory protein (StAR), a mitocho

24 of outer mitochondrial membrane 22 (Tom22), steroidogenic acute regulatory protein (StAR), and 3beta

25 eased mRNAs of melanocortin receptor type 2, steroidogenic acute regulatory protein (StAR), and gene

26 ther key steroidogenic transcripts including steroidogenic acute regulatory protein (STAR), cytochrom

27 sfer (START) domain, first identified in the steroidogenic acute regulatory protein (StAR), is involv

28 The steroidogenic acute regulatory protein (StAR), the first

29 Expression of steroidogenic acute regulatory protein (StAR), the rate-

30 e transcription factors c-Fos/c-Jun regulate steroidogenic acute regulatory protein (StAR), which fac

31 re approximately 30% identity, and each is a steroidogenic acute regulatory protein (StAR)-related li

32 tivating protein, STARD10 is a member of the steroidogenic acute regulatory protein (StAR)-related li

33 rial and cytosolic components, including the steroidogenic acute regulatory protein (STAR).

34 steroids in response to stress, requires the steroidogenic acute regulatory protein (StAR).

35 pha); and the hormone-induced PKA substrate, steroidogenic acute regulatory protein (StAR).

36 ndrial cholesterol transport mediated by the steroidogenic acute regulatory protein (StAR).

37 glomerulosa cells requires induction of the steroidogenic acute regulatory protein (StAR).

38 ein levels of SREBP2, HMG-CoA reductase, and steroidogenic acute regulatory protein (StAR; a protein

39 The expression of steroidogenic acute regulatory protein decreased during

40 attenuated GX sPLA2-dependent inhibition of steroidogenic acute regulatory protein expression and pr

41 was probably explained by reduced testicular steroidogenic acute regulatory protein expression, which

42 sing liver X receptor-mediated activation of steroidogenic acute regulatory protein expression.

43 he reduction of testosterone levels, because steroidogenic acute regulatory protein is crucial for te

44 The Star (steroidogenic acute regulatory protein)-related transfer

45 enesis (evaluated by levels of testosterone, steroidogenic acute regulatory protein, 3beta-hydroxyste

46 K activation and subsequent up-regulation of steroidogenic acute regulatory protein, a steroid transp

47 eceptor accessory protein messenger RNAs and steroidogenic acute regulatory protein, and a reduction

48 ts of cholesterol utilization, including the steroidogenic acute regulatory protein, StAR, a novel LX

49 nal corticosterone levels and an increase in steroidogenic acute regulatory protein, steroidogenic fa

50 nal glands were collected for measurement of steroidogenic acute regulatory protein, steroidogenic fa

51 ecutive hotdog-fold domains and a C-terminal steroidogenic acute regulatory protein-related lipid tra

52 nd that amino acids 79-271 of LPCAT1 and the steroidogenic acute regulatory protein-related lipid tra

53 tative pleckstrin homology (PH) domain and a steroidogenic acute regulatory protein-related lipid-tra

54 cific cholesterol carriers, particularly the steroidogenic acute regulatory protein.

55 The steroidogenic acute regulatory-related lipid-transfer (S

56 d synthesis could also be activated in mouse steroidogenic adrenal cells by transfection with cDNA en

57 1-deleted cells and our studies suggest that steroidogenic adrenal cells during foetal stages require

58 press Gli1, a known marker of progenitors of steroidogenic adrenal cells.

59 fferentiation but represses the migration of steroidogenic adrenal precursors into the gonad.

60 nown as NR5A1) is a crucial mediator of both steroidogenic and nonsteroidogenic tissue differentiatio

61 Models for steroidogenic and thyroid-related effects could not be d

62 omal cytochromes P450 that catalyze critical steroidogenic and xenobiotic reactions, and to two heme

63 A ToxCast HTS assays for estrogen, androgen, steroidogenic, and thyroid-disrupting mechanisms to clas

64 A ToxCast HTS assays for estrogen, androgen, steroidogenic, and thyroid-disrupting mechanisms to clas

65 anisms of toxicity include disruption of the steroidogenic biosynthesis pathway and oxidative stress.

66 number, distribution, and most importantly, steroidogenic capacity and suggest that abnormal express

67 our data implies that Wnt4 does not regulate steroidogenic cell differentiation but represses the mig

68 These studies reveal the complex nature of steroidogenic cell differentiation during urogenital dev

69 ein are expressed at varying levels in model steroidogenic cell lines and the adrenal, with only low

70 absence of TSPO in different mouse and human steroidogenic cell lines had no effect on steroidogenesi

71 selective HDL CE uptake mediated by SR-BI in steroidogenic cell lines.

72 role of WNT4 was to inhibit endothelial and steroidogenic cell migration into the developing ovary.

73 Import of TSPO into steroidogenic cell mitochondria is regulated by cAMP.

74 The level of import of TSPO into steroidogenic cell mitochondria was increased following

75 etween the mesonephros and the gonad harbors steroidogenic cell precursors that are repressed by the

76 the sex-specific vasculature and to regulate steroidogenic cell recruitment.

77 To circumvent this issue, steroidogenic cell-targeting Nr5a1-Cre mice were crossed

78 ed for the first time, rendering adipocyte a steroidogenic cell.

79 two separate origins of adult adrenocortical steroidogenic cells (fetal adrenal cortex and/or the adr

80 Supporting cells (Sertoli and granulosa) and steroidogenic cells (Leydig and theca-interstitium) are

81 lasts and COS-7 kidney) but not in TSPO-rich steroidogenic cells (MA-10 Leydig) with high basal Tspo

82 ed basal Tspo promoter activity in TSPO-rich steroidogenic cells (MA-10 Leydig), as well as basal and

83 Using isolated mitochondria from steroidogenic cells and cell-free synthesized AS, we fir

84 plantation phenotype to the clock in ovarian steroidogenic cells and distinguishes it from more gener

85 eproduction by its actions to affect ovarian steroidogenic cells and to induce apoptosis of corpus lu

86 idogenic acute regulatory (StAR) proteins in steroidogenic cells are implicated in the delivery of ch

87 Corticotropin was detected in steroidogenic cells arranged in clusters that were disse

88 determination caused ectopic development of steroidogenic cells at the embryonic stage.

89 In mice, steroid synthesis is activated in steroidogenic cells by pituitary hormones, which concomi

90 alpha-OOH can be transported to/into Mito of steroidogenic cells by StAR proteins and therein induce

91 1a1 reporter mice, we definitively show that steroidogenic cells can migrate from the mesonephros int

92 Insl3 showing that they are a population of steroidogenic cells distinct from Leydig cells.

93 ital ridge somatic cells differentiated into steroidogenic cells in both male and female gonads.

94 pin, which is produced by a subpopulation of steroidogenic cells in the hyperplastic adrenals.

95 tant embryos to be a significant increase of steroidogenic cells in the Wnt4 -/- gonad.

96 idogenic cortex, which reduced the number of steroidogenic cells in the zona fasciculata of the adren

97 ed and the somatic cells differentiated into steroidogenic cells instead of supporting cells.

98 recently showed that high levels of TSPO in steroidogenic cells may be due to high constitutive expr

99 ata suggest that elevated TSPO expression in steroidogenic cells may be due to high constitutive expr

100 Steroidogenic cells of the adrenal and gonad are thought

101 irst demonstration via lineage analysis that steroidogenic cells originate from nephrogenous mesenchy

102 high density lipoproteins by hepatocytes and steroidogenic cells through a process mediated by scaven

103 cretory and glandular tissues, especially in steroidogenic cells, and its expression is altered in ce

104 about SR-BI posttranslational regulation in steroidogenic cells, we examined the roles of Na(+)/H(+)

105 steroid-producing fetal Leydig cells and non-steroidogenic cells.

106 cretory and glandular tissues, especially in steroidogenic cells.

107 nchyme contributes to both Sertoli cells and steroidogenic cells.

108 where it is metabolized into pregnenolone in steroidogenic cells.

109 ein (HDL) cholesteryl ester into hepatic and steroidogenic cells.

110 hat capsular RSPO3 signals to the underlying steroidogenic compartment to induce beta-catenin signali

111 All steroidogenic components were present, although only ker

112 ic GATA4- and Gli1-positive cells within the steroidogenic cortex, which reduced the number of steroi

113 Co-transfection of non-steroidogenic COS-1 cells with P450c17 and p38 expressio

114 ormation in both steroidogenic MA-10 and non-steroidogenic COS-F2-130 cells that were engineered to m

115 The importance of selectivity over other steroidogenic CYP enzymes, in particular 11beta-hydroxyl

116 It up-regulates the expression of the steroidogenic Cyp11a1 gene in the adrenal in a pathway s

117 econd electron from cytochrome b5, for human steroidogenic CYP17A1, the cytochrome P450 reductase FMN

118 and the catalytic domain of the bifunctional steroidogenic cytochrome P450 17A1 (CYP17A1) were invest

119 for certain structural features of the human steroidogenic cytochrome P450 17A1 (CYP17A1).

120 ny mutations that are found in patients with steroidogenic diseases, the active site reveals multiple

121 the human fetal testis is insensitive to the steroidogenic effects of phthalates, the effects on germ

122 roendocrine, immunomodulatory, metabolic and steroidogenic effects to that of leptin is consistent wi

123 arvested and assessed for histopathology and steroidogenic end points.

124 used antifungal chemical that inhibits a key steroidogenic enzyme [cytochrome P450(CYP19) aromatase]

125 The steroidogenic enzyme CYP17 is responsible for catalyzing

126 ty of them are differentiated overexpressing steroidogenic enzyme CYP17, a theca cell-specific marker

127 fied enzymes demonstrated involvement of the steroidogenic enzyme cytochrome P450scc (CYP11A1) as wel

128 Cytochrome P450c17, a steroidogenic enzyme encoded by the CYP17A1 gene, cataly

129 ases the mRNA and protein levels of multiple steroidogenic enzyme genes.

130 ralateral slices were treated with steroids, steroidogenic enzyme inhibitors or gonadal tissue itself

131 FSH induction of select steroidogenic enzyme mRNAs, including Cyp19a1, is enhanc

132 levels and enzymatic activity of CYP11A1, a steroidogenic enzyme regulating CD8(+) T-cell conversion

133 ehydrogenase type IV (HSD17B4), coding for a steroidogenic enzyme that converts estradiol (E2) into a

134 The aberrant expression of the steroidogenic enzyme transcripts was detected in CTCs fr

135 Steroidogenic enzyme transcripts were evaluated by quant

136 (4)-abiraterone (D4A), which blocks multiple steroidogenic enzymes and antagonizes the androgen recep

137 s were investigated for mRNA and protein for steroidogenic enzymes and for endogenous synthesis of te

138 Expression of steroidogenic enzymes and GC synthesis in ex vivo organ

139 ortical zonation and defective expression of steroidogenic enzymes as well as renal histology in keep

140 In contrast, the steroidogenic enzymes CYP11A1 and CYP11B1 involved in gl

141 h concomitant reduction in expression of the steroidogenic enzymes CYP11A1, CYP17A1 and HSD17B3, and

142 onal and glial cells, which begin to express steroidogenic enzymes early in development.

143 Deficient activities of multiple steroidogenic enzymes have been reported without and wit

144 of aldosterone synthesis and the activity of steroidogenic enzymes in adrenal ZG cells.

145 for Leydig cell maturation and regulation of steroidogenic enzymes in adulthood.

146 ted androgen levels and transcripts encoding steroidogenic enzymes in benign prostate tissue, untreat

147 lism, or altered expression or activities of steroidogenic enzymes in female Cyp2j5 (-/-) mice, but t

148 its effect on the expression of a number of steroidogenic enzymes in the ERbeta ligand metabolic pat

149 ta(4) isomerases (3beta-HSDs), which are key steroidogenic enzymes in vertebrates, and is exclusively

150 Although the lung expresses all steroidogenic enzymes necessary for de novo synthesis of

151 These steroidogenic enzymes represent targets for complete sup

152 Steroidogenic enzymes required for androgen synthesis fr

153 Mouse lung tissue was found to express steroidogenic enzymes required for the synthesis of cort

154 One of the crucial steroidogenic enzymes, AKR1C3, was significantly elevate

155 cloning fragments of the genes encoding two steroidogenic enzymes, CYP17 and CYP19, and examining th

156 CYP2C19, CYP2D6, and CYP3A4 and the crucial steroidogenic enzymes, CYP17 and CYP19.

157 and/or transcriptional repression of several steroidogenic enzymes, in combination with GnRH analogs

158 higher transcript levels for AR and several steroidogenic enzymes, including SRD5A1, SRD5A3, and AKR

159 ases displayed alterations in genes encoding steroidogenic enzymes, including up-regulated expression

160 ition of PDE8s cause increased expression of steroidogenic enzymes.

161 ns into hydroxy derivatives through existing steroidogenic enzymes.

162 ross all hormones on this latent generalized steroidogenic factor (Cohen's d=0.37, P=0.0009) and this

163 lear receptor NR5A subfamily, which includes steroidogenic factor 1 (SF-1) and liver receptor homolog

164 Here, we report that steroidogenic factor 1 (SF-1) and liver receptor homolog

165 Cooperative participation of multiple steroidogenic factor 1 (SF-1) elements with the downstre

166 ysiological approaches, we first reveal that steroidogenic factor 1 (SF-1) green fluorescent protein

167 Steroidogenic factor 1 (SF-1) is a transcription factor

168 Steroidogenic factor 1 (SF-1) is an orphan nuclear recep

169 The nuclear receptor steroidogenic factor 1 (SF-1) is essential for adrenal d

170 The nuclear receptor steroidogenic factor 1 (SF-1) is essential for steroidog

171 The transcription factor steroidogenic factor 1 (SF-1) is exclusively expressed i

172 In the central nervous system, steroidogenic factor 1 (SF-1) is required for terminal d

173 regulated, we monitored their expression in steroidogenic factor 1 (SF-1) knock-out mice.

174 We found that mice lacking FOXO1 in steroidogenic factor 1 (SF-1) neurons of the VMH are lea

175 The orphan nuclear receptor steroidogenic factor 1 (SF-1) regulates the differentiat

176 dent on the master transcriptional regulator Steroidogenic Factor 1 (SF-1), and zG-specific Sf-1 dele

177 The steroidogenic factor 1 (SF-1, also known as NR5A1) is a

178 The transcription factor steroidogenic factor 1 (SF-1; also known as NR5A1) is a

179 iver receptor homologue 1 (LRH-1; NR5A2) and steroidogenic factor 1 (SF-1; NR5A1) have therapeutic po

180 including the constitutively active receptor steroidogenic factor 1 (SF-1; NR5A1), is proposed to rep

181 romoting the binding of the nuclear receptor steroidogenic factor 1 (SF1) (Ad4BP, NR5A1) to the promo

182 pped to the proximal Lhb promoter containing steroidogenic factor 1 (SF1), pituitary homeobox 1 (PTX1

183 vestigate this, we optogenetically activated steroidogenic factor 1 (SF1)-expressing neurons in the d

184 ocortin (POMC)-, single-minded 1 (Sim1)-, or steroidogenic factor 1 (SF1)-expressing neurons in the h

185 , we ectopically activated the Hh pathway in Steroidogenic factor 1 (SF1)-positive somatic cell precu

186 essing the VMH-specific transcription factor steroidogenic factor 1 (SF1).

187 ncer in mice, and that it does so along with steroidogenic factor 1 (SF1, encoded by the gene Nr5a1 (

188 The nuclear receptor steroidogenic factor 1 (Sf1, Nr5a1) is essential for adr

189 The nuclear receptor steroidogenic factor 1 (Sf1, Nr5a1, Ad4bp) is crucial fo

190 The vertebrate nuclear hormone receptor steroidogenic factor 1 (SF1; NR5A1) controls reproductiv

191 more abundant than mRNA for both P450c17 and steroidogenic factor 1 in sebaceous glands and SEB-1 cel

192 significance of COUP-TFII expression in the steroidogenic factor 1 neurons, we generated hypothalami

193 to a subpopulation of neurons expressing the steroidogenic factor 1 transcription factor, known to pl

194 identified through its interaction with SF1 (steroidogenic factor 1) and has been demonstrated to be

195 , neuropeptide Y/agouti-related peptide, and steroidogenic factor 1), those of neurons derived from t

196 t of steroidogenic acute regulatory protein, steroidogenic factor 1, and dosage-sensitive sex reversa

197 e in steroidogenic acute regulatory protein, steroidogenic factor 1, and melanocortin type 2 receptor

198 one acetylation, sphingosine is a ligand for steroidogenic factor 1, and nuclear accumulation of cera

199 oxin reductase, and the transcription factor steroidogenic factor 1, P450scc converts cholesterol to

200 h) signaling is responsible for transforming steroidogenic factor 1-positive (SF1(+)) progenitors int

201 Steroidogenic factor SF-1, a constitutively active nucle

202 alysis confirmed that one generalized latent steroidogenic factor was driving much of the variation i

203 Steroidogenic factor-1 (known as NR5A1) is a key regulat

204 signal, cAMP and the orphan nuclear receptor steroidogenic factor-1 (NR5A1).

205 sequences for the orphan nuclear receptors, steroidogenic factor-1 (or NR5A1), and fetoprotein trans

206 Steroidogenic factor-1 (SF-1) and liver receptor homolog

207 The nuclear receptor steroidogenic factor-1 (SF-1) has been implicated as a d

208 clin D2 as well as inhibin-alpha, aromatase, steroidogenic factor-1 (SF-1), cholesterol side chain (S

209 rat LC relates inversely to LC expression of steroidogenic factor-1 (SF-1)-dependent genes (StAR, Cyp

210 (NR5A), liver receptor homolog-1 (LRH-1) and steroidogenic factor-1 (SF-1).

211 The nuclear receptor steroidogenic factor-1 (SF-1, NR5A1) is a key regulator

212 nt of VMH efferent projections, as marked by steroidogenic factor-1 (SF-1; NR5A1).

213 sed the promoter that controls expression of Steroidogenic Factor-1 (SF1) to drive Cre-recombinase-me

214 depolarizes and increases the firing rate of steroidogenic factor-1 (SF1)-positive neurons in the VMH

215 Because steroidogenic factor-1 and Amh are important for proper

216 ontrol the ability of the protein to bind to steroidogenic factor-1 and the coactivator GCN5 (general

217 To target VMH MC3R expression, we used the steroidogenic factor-1 Cre transgenic mouse.

218 elopment and has been shown to interact with steroidogenic factor-1 in mammals, leading to the suppre

219 CYP17 gene by periodically interacting with steroidogenic factor-1 in response to ACTH signaling.

220 ediated through functional interactions with steroidogenic factor-1 that involve four acidic residues

221 Here, the crystal structures of human NR5A1 (steroidogenic factor-1, SF-1) ligand binding domain (LBD

222 Steroidogenic factor-1-expressing (SF-1-expressing) neur

223 eurons that express the transcription factor steroidogenic-factor 1 (VMN(SF1) neurons) blocks recover

224 Because the expression levels of steroidogenic factors are low and constant over time in

225 hat are noted prior to molecular evidence of steroidogenic failure.

226 rine regulatory role to modulate Leydig cell steroidogenic function.

227 nal morphology that was characterized by non-steroidogenic GATA4- and Gli1-positive cells within the

228 A1 [ABCA1], apoE, SREBP-1c) while preventing steroidogenic gene (StAR) expression.

229 ted germ cell (MNG) induction and suppressed steroidogenic gene expression and testosterone productio

230 sed to identify microRNAs (miRNAs) affecting steroidogenic gene expression under hypoxia.

231 nt of pituitary regulation via modulation of steroidogenic gene expression, and (ii) the role of lept

232 duction but were resistant to suppression of steroidogenic gene expression.

233 sex steroid synthesis by acting directly on steroidogenic gene expression.

234 us Dax-1 downregulates the expression of the steroidogenic gene products CYP11A1 and StAR in both H29

235 The expression of the steroidogenic gene products steroidogenic acute regulato

236 eroidogenic factor 1 (SF-1) is essential for steroidogenic gene transcription.

237 ells resulted in the downregulation of seven steroidogenic genes and one of these, CYP19A1 (aromatase

238 that SF1 is a regulator of the expression of steroidogenic genes in all three organs.

239 day 40 pc, followed by initiation of AMH and steroidogenic genes required for androgen production at

240 ted kinase (ERK)1/2, increased expression of steroidogenic genes, and increased neutral lipid storage

241 he SF1 R103Q mutation impaired activation of steroidogenic genes, without affecting synergistic SF-1

242 nd coactivator proteins with the promoter of steroidogenic genes.

243 SF-1 is a key transcription factor for all steroidogenic genes.

244 SPH, increases the transcription of multiple steroidogenic genes.

245 e mRNA expression of CYP17 and several other steroidogenic genes.

246 creased expression of StAR and several other steroidogenic genes.

247 ely achieved clinical remission, inferring a steroidogenic-independent and MC1R-dispensable anti-prot

248 coelomic epithelium contributes only to non-steroidogenic interstitial cells.

249 e to the adult seminiferous tubules, whereas steroidogenic Leydig cells and other less well character

250 common mechanism in the control of multiple steroidogenic lineages.

251 tein S6 kinase 1 (S6K1) signaling pathway in steroidogenic luteal cells.

252 the stimulation of steroid formation in both steroidogenic MA-10 and non-steroidogenic COS-F2-130 cel

253 In the hCG-dependent steroidogenic MA-10 mouse Leydig cell line, the 14-3-3ga

254 Direct estrogenic, androgenic, or steroidogenic mechanisms are unlikely for NAs based on t

255 ngly associated with distinct differences in steroidogenic melanocortin 2 receptor (MC2R) mRNA expres

256 ng adrenocorticotropic hormone (ACTH) or non-steroidogenic melanocortin peptides attenuates proteinur

257 The results indicate that monitoring steroidogenic metabolites in patients with PCa may provi

258 tivity in transfected cells or with isolated steroidogenic mitochondria, nevertheless, can bind as mu

259 motions of lipid droplet (LD) organelles in steroidogenic mouse adrenal cortical (Y-1) cells with CA

260 tely ablated progesterone conversion in both steroidogenic mouse Leydig MA-10 and human adrenal NCI c

261 ger-like protrusions, and a misexpression of steroidogenic or FLC- and ALC-specific genes.

262 The brain is a steroidogenic organ and is thus dependent on estrogen fo

263 ere fertile, and cholesteryl ester stores in steroidogenic organs were essentially unaffected.

264 e evolutionarily conserved Hh pathway to the steroidogenic organs, demonstrating how Hh signaling can

265 yed from peripheral tissues to the liver and steroidogenic organs.

266 stimulating hormone (NDP-MSH), a potent non-steroidogenic pan-melanocortin receptor agonist, on the

267 Many key factors within the adrenal steroidogenic pathway have been identified and studied,

268 is the first and rate-limiting enzyme in the steroidogenic pathway, converting cholesterol to pregnen

269 ovel agents capable of inhibiting intracrine steroidogenic pathways within the prostate tumor microen

270 The non-steroidogenic progenitor cells retain their undifferenti

271 Inhibition of calcium signaling in the steroidogenic prothoracic gland results in the accumulat

272 Steroidogenic rates are also critically dependent on the

273 ntally in the rat, our results show that the steroidogenic regulatory network architecture is suffici

274 eveloped a mathematical model of the adrenal steroidogenic regulatory network that accounts for key r

275 r steroidogenesis), and a failure to mount a steroidogenic response to ACTH.

276 The acute steroidogenic response, which produces steroids in respo

277 P2 protein expression and partially restored steroidogenic responses, confirming the requirement of S

278 the twin fetuses to determine adrenocortical steroidogenic sensitivity to exogenous ACTH.

279 In this study, we have generated steroidogenic-specific Cre-expressing mice to lineage ma

280 mutagenesis, we have provided evidence that steroidogenic SR-BI is a direct target of miRNA-125a and

281 both miRNA-125a and miRNA-455, by targeting steroidogenic SR-BI, negatively regulate selective HDL C

282 ted mice, S-norfluoxetine, a selective brain steroidogenic stimulant (SBSS), in doses (0.45-1.8 mumol

283 Steroidogenic stimulation of mouse MA-10 Leydig cells wi

284 otype, StarD4 and StarD5 were not induced by steroidogenic stimuli in Leydig cells.

285 Tcf21-expressing cells give rise only to non-steroidogenic stromal adrenocortical cells, which also e

286 idogenesis in CD8(+) T cells, a nonclassical steroidogenic tissue, to a proallergic differentiation p

287 yzes the hydrolysis of cholesteryl esters in steroidogenic tissues and, thus, facilitates cholesterol

288 PDE11A is highly expressed in endocrine steroidogenic tissues, especially the testis, and mice w

289 and pathophysiological processes in several steroidogenic tissues, including the testis, ovary, adre

290 rt into mitochondria, is highly expressed in steroidogenic tissues, metastatic cancer, and inflammato

291 erol is transported into the mitochondria of steroidogenic tissues, the first steroid, pregnenolone,

292 the mouse, human PAP7 is highly expressed in steroidogenic tissues, where it follows the pattern of P

293 nucleotides by phosphodiesterases (PDEs) in steroidogenic tissues.

294 n could potentially influence cancer risk in steroidogenic tissues.

295 tral cholesteryl ester hydrolase activity in steroidogenic tissues.

296 tochondrial cholesterol transport complex in steroidogenic tissues.

297 oncerning mechanisms of their secretion from steroidogenic tissues.

298 l for formation, development and function of steroidogenic tissues.

299 ion of SR-BI and miRNA-125a and miRNA-455 in steroidogenic tissues/cells and that both miRNA-125a and

300 P450, subfamily XVII (CYP17A1) and other key steroidogenic transcripts including steroidogenic acute