ライフサイエンスコーパス: steroidogenic factor 1

1 n the adrenal strategy and is independent of steroidogenic factor-1.

2 StAR transcription by lipoproteins requires steroidogenic factor-1.

3 Cotransfection of C/EBPalpha or -beta and steroidogenic factor 1, a transcription factor required

4 Steroidogenic factor-1/adrenal 4-binding protein (SF-1/A

5 Leydig cell differentiation by up-regulating Steroidogenic Factor 1 and P450 Side Chain Cleavage enzy

6 Because steroidogenic factor-1 and Amh are important for proper

7 ontrol the ability of the protein to bind to steroidogenic factor-1 and the coactivator GCN5 (general

8 identified through its interaction with SF1 (steroidogenic factor 1) and has been demonstrated to be

9 the Wnt signaling pathway, beta-catenin and steroidogenic factor 1, and chromatin immunoprecipitatio

10 t of steroidogenic acute regulatory protein, steroidogenic factor 1, and dosage-sensitive sex reversa

11 e in steroidogenic acute regulatory protein, steroidogenic factor 1, and melanocortin type 2 receptor

12 one acetylation, sphingosine is a ligand for steroidogenic factor 1, and nuclear accumulation of cera

13 pting recruitment of beta-catenin at or near steroidogenic factor 1 binding sites present in multiple

14 al and depend on the orphan nuclear receptor steroidogenic factor-1, but the placental strategy for t

15 To target VMH MC3R expression, we used the steroidogenic factor-1 Cre transgenic mouse.

16 Steroidogenic factor-1-expressing (SF-1-expressing) neur

17 abundance of mRNA for P450scc, P450c17, and steroidogenic factor 1 in SEB-1 sebocytes and sebaceous

18 more abundant than mRNA for both P450c17 and steroidogenic factor 1 in sebaceous glands and SEB-1 cel

19 elopment and has been shown to interact with steroidogenic factor-1 in mammals, leading to the suppre

20 CYP17 gene by periodically interacting with steroidogenic factor-1 in response to ACTH signaling.

21 Steroidogenic factor-1 (known as NR5A1) is a key regulat

22 arbon receptor (AhR)-binding sites and three steroidogenic factor-1 motifs that are associated with c

23 significance of COUP-TFII expression in the steroidogenic factor 1 neurons, we generated hypothalami

24 signal, cAMP and the orphan nuclear receptor steroidogenic factor-1 (NR5A1).

25 sequences for the orphan nuclear receptors, steroidogenic factor-1 (or NR5A1), and fetoprotein trans

26 oxin reductase, and the transcription factor steroidogenic factor 1, P450scc converts cholesterol to

27 h) signaling is responsible for transforming steroidogenic factor 1-positive (SF1(+)) progenitors int

28 lear receptor NR5A subfamily, which includes steroidogenic factor 1 (SF-1) and liver receptor homolog

29 Here, we report that steroidogenic factor 1 (SF-1) and liver receptor homolog

30 Products of steroidogenic factor 1 (SF-1) and Wilms' tumor 1 (WT1) g

31 It contains a steroidogenic factor 1 (SF-1) element (-668) that binds

32 Cooperative participation of multiple steroidogenic factor 1 (SF-1) elements with the downstre

33 ysiological approaches, we first reveal that steroidogenic factor 1 (SF-1) green fluorescent protein

34 The orphan nuclear receptor steroidogenic factor 1 (SF-1) is a critical developmenta

35 Steroidogenic factor 1 (SF-1) is a transcription factor

36 Steroidogenic factor 1 (SF-1) is an orphan nuclear recep

37 Steroidogenic factor 1 (SF-1) is an orphan nuclear recep

38 Steroidogenic factor 1 (SF-1) is an orphan nuclear recep

39 The nuclear receptor steroidogenic factor 1 (SF-1) is essential for adrenal d

40 The nuclear receptor steroidogenic factor 1 (SF-1) is essential for steroidog

41 The transcription factor steroidogenic factor 1 (SF-1) is exclusively expressed i

42 The orphan nuclear receptor steroidogenic factor 1 (SF-1) is expressed in the adrena

43 In the central nervous system, steroidogenic factor 1 (SF-1) is required for terminal d

44 regulated, we monitored their expression in steroidogenic factor 1 (SF-1) knock-out mice.

45 We found that mice lacking FOXO1 in steroidogenic factor 1 (SF-1) neurons of the VMH are lea

46 The orphan nuclear receptor steroidogenic factor 1 (SF-1) regulates the differentiat

47 sponsiveness to 8-Br-cAMP in the presence of steroidogenic factor 1 (SF-1) when placed behind a minim

48 aled two motifs resembling binding sites for steroidogenic factor 1 (SF-1), a member of the orphan nu

49 Steroidogenic factor 1 (SF-1), an orphan member of the i

50 dent on the master transcriptional regulator Steroidogenic Factor 1 (SF-1), and zG-specific Sf-1 dele

51 as that of another orphan nuclear receptor, steroidogenic factor 1 (SF-1), that is required for deve

52 form the VMH is the orphan nuclear receptor, steroidogenic factor 1 (SF-1), which can be detected in

53 nteractions with the orphan nuclear receptor steroidogenic factor 1 (SF-1).

54 it is regulated by the transcription factor, steroidogenic factor 1 (SF-1).

55 The steroidogenic factor 1 (SF-1, also known as NR5A1) is a

56 The transcription factor steroidogenic factor 1 (SF-1; also known as NR5A1) is a

57 iver receptor homologue 1 (LRH-1; NR5A2) and steroidogenic factor 1 (SF-1; NR5A1) have therapeutic po

58 including the constitutively active receptor steroidogenic factor 1 (SF-1; NR5A1), is proposed to rep

59 Two transcription factors, steroidogenic factor-1 (SF-1) and early growth response-

60 Steroidogenic factor-1 (SF-1) and liver receptor homolog

61 inding sites for the orphan nuclear receptor steroidogenic factor-1 (SF-1) are occupied in vitro by u

62 Analysis of a patient heterozygous for the steroidogenic factor-1 (SF-1) gene suggested that reduce

63 The nuclear receptor steroidogenic factor-1 (SF-1) has been implicated as a d

64 a regulation of the phosphorylation state of steroidogenic factor-1 (SF-1) in mediating ACTH/cAMP-dep

65 Steroidogenic factor-1 (SF-1) is an orphan nuclear recep

66 conservation of a sequence homologous to the steroidogenic factor-1 (SF-1) regulatory element of cyto

67 Among these, the orphan receptor steroidogenic factor-1 (SF-1) was found to potently tran

68 ear receptor that represses transcription by steroidogenic factor-1 (SF-1), a factor that regulates e

69 he LHbeta gene in vitro through synergy with steroidogenic factor-1 (SF-1), a protein required for go

70 have implicated the orphan nuclear receptor, steroidogenic factor-1 (SF-1), and the early growth resp

71 clin D2 as well as inhibin-alpha, aromatase, steroidogenic factor-1 (SF-1), cholesterol side chain (S

72 The orphan nuclear receptor, steroidogenic factor-1 (SF-1), is expressed in the pitui

73 trophoretic mobility-shift analyses a distal steroidogenic factor-1 (SF-1)-binding site that is essen

74 rat LC relates inversely to LC expression of steroidogenic factor-1 (SF-1)-dependent genes (StAR, Cyp

75 2(R)-OHC), 25-OHC, and 27-OHC each increased steroidogenic factor-1 (SF-1)-mediated StAR gene transac

76 red for synergistic activation by NGFI-A and steroidogenic factor-1 (SF-1).

77 (NR5A), liver receptor homolog-1 (LRH-1) and steroidogenic factor-1 (SF-1).

78 The nuclear receptor steroidogenic factor-1 (SF-1, NR5A1) is a key regulator

79 nt of VMH efferent projections, as marked by steroidogenic factor-1 (SF-1; NR5A1).

80 Here, the crystal structures of human NR5A1 (steroidogenic factor-1, SF-1) ligand binding domain (LBD

81 romoting the binding of the nuclear receptor steroidogenic factor 1 (SF1) (Ad4BP, NR5A1) to the promo

82 latory protein 2) was identified using mouse steroidogenic factor 1 (SF1) as bait in a yeast two-hybr

83 out mice lacking the orphan nuclear receptor steroidogenic factor 1 (SF1) exhibit a complex endocrine

84 eutherian mammals, such as mice and humans, steroidogenic factor 1 (SF1) plays important roles in th

85 The expression of steroidogenic factor 1 (Sf1), a nuclear receptor essenti

86 pped to the proximal Lhb promoter containing steroidogenic factor 1 (SF1), pituitary homeobox 1 (PTX1

87 Mutations were introduced into conserved steroidogenic factor 1 (SF1)- and SOX9-binding sites wit

88 vestigate this, we optogenetically activated steroidogenic factor 1 (SF1)-expressing neurons in the d

89 ocortin (POMC)-, single-minded 1 (Sim1)-, or steroidogenic factor 1 (SF1)-expressing neurons in the h

90 , we ectopically activated the Hh pathway in Steroidogenic factor 1 (SF1)-positive somatic cell precu

91 essing the VMH-specific transcription factor steroidogenic factor 1 (SF1).

92 ncer in mice, and that it does so along with steroidogenic factor 1 (SF1, encoded by the gene Nr5a1 (

93 The nuclear receptor steroidogenic factor 1 (Sf1, Nr5a1) is essential for adr

94 The nuclear receptor steroidogenic factor 1 (Sf1, Nr5a1, Ad4bp) is crucial fo

95 The vertebrate nuclear hormone receptor steroidogenic factor 1 (SF1; NR5A1) controls reproductiv

96 sed the promoter that controls expression of Steroidogenic Factor-1 (SF1) to drive Cre-recombinase-me

97 depolarizes and increases the firing rate of steroidogenic factor-1 (SF1)-positive neurons in the VMH

98 ption from a -966 StAR promoter in which the steroidogenic factor-1 site at -135 was abolished, indic

99 ediated through functional interactions with steroidogenic factor-1 that involve four acidic residues

100 , neuropeptide Y/agouti-related peptide, and steroidogenic factor 1), those of neurons derived from t

101 to a subpopulation of neurons expressing the steroidogenic factor 1 transcription factor, known to pl

102 eurons that express the transcription factor steroidogenic-factor 1 (VMN(SF1) neurons) blocks recover

103 ytochrome P450 17-hydroxylase (P450c17), and steroidogenic factor 1 was documented in human facial sk