ライフサイエンスコーパス: sticky

1 ntermediates, some of which are large and/or sticky.

2 n surfaces, yet few macroscopic surfaces are sticky.

3 ion, and shedding, whereas the citron kinase Sticky acts on the N terminus of Anillin to retain it at

4 al target for the complementary treatment of sticky airway secretions by enhancing epithelial fluid s

5 cancer have shorter telomeres, which become sticky and cause telomeric bridges to form, with subsequ

6 isorder characterized by the accumulation of sticky and heavy mucus that can damage several organs.

7 leads to phenotypic heterogeneity, in which sticky and non-sticky cells occur side by side on the su

8 olayer resist in an oxygen-rich environment, sticky and nonsticky regions on the surface are directly

9 lus, and by sensory disruption, in which the sticky and potent secretions cause high-amplitude, long-

10 ndicate that substrate binding is relatively sticky and that proton transfers do not occurr during th

11 rve that fluffy soot aggregates are the most sticky and unstable.

12 backbone on a beta-strand is thought of as "sticky" and beta-strand pairing stabilizes many naturall

13 prefactor changes sign, the surfaces become sticky, and a finite force is required to separate them.

14 Thus, OAS is sticky, and a value of 1.5 is calculated for the forward

15 hree different packing mechanisms, Slippery, Sticky, and Anisotropic, respectively.

16 albumin and hemoglobin that are viscous and sticky are extremely difficult to mix rapidly.

17 ively) interacts via selective short-range ("sticky") attraction.

18 Translating sticky biological molecules-such as mussel foot proteins

19 the nucleus of eukaryotic cells; it is the 'sticky bit' that remains after aggressive DNAse digestio

20 nderstand the relationship of dynamics among sticky bonds, single molecules, and the entire network.

21 the low-dimensional manifolds connected by "sticky" boundary conditions.

22 developed an aptamer-siRNA chimera using a "sticky bridge" method by conjugating the aptamer with si

23 onate (100 parts), bitumen emulsion (or any 'sticky' carbon source) (12 parts) and sulphur (60 parts)

24 release' and 'stealthy in circulation versus sticky (cell-binding) in tumor' at the right places in o

25 We particularly focus on the evolution of a 'sticky' cell type that is required for surface attachmen

26 The sticky cells not only facilitate their own attachment, b

27 typic heterogeneity, in which sticky and non-sticky cells occur side by side on the surface.

28 e their own attachment, but also that of non-sticky cells.

29 ), missensed (n = 1), senseless (n = 1), and sticky ch1 (n = 1).

30 gluon, hoi-polloi, melted, pebble, skittles, sticky ch1, and vegetable.

31 These observations indicate that sticky/citron kinase functions to regulate both actin-my

32 the Drosophila sticky gene and we show that sticky/citron kinase is required for histone H3-K9 methy

33 is essential for completion of cytokinesis, sticky/citron kinase phenotypes disrupting neurogenesis

34 The sticky/citron kinase protein is a conserved regulator of

35 Ca(2+) sparks generated by the sticky cluster model resemble those observed experimenta

36 Here we present a new model, "sticky cluster," of SR Ca(2+) release that simulates Ca(

37 The mutant formed sticky colonies and viscous liquid cultures; analysis of

38 d in vitro, and third, required to adopt the sticky conformation.

39 the DNA/DNA associated triplex region of the sticky conformations account for these observations.

40 gregates of mHtt exclude chromatin and form 'sticky' decoy traps that impede target search processes

41 ntral spindle are recruited normally in such STICKY-depleted cells that nevertheless display asymmetr

42 Cl(2) (or MnCl(2)) are required to stabilize sticky DNA (a dumbbell-shaped structure) in plasmids wit

43 investigations also provide strong data for sticky DNA as a single long triplex.

44 ropensity of the GAA.TTC tracts to adopt the sticky DNA conformation and the inhibition of intramolec

45 Hence, our results demonstrate that sticky DNA exists and functions in E. coli.

46 studies support the intramolecular nature of sticky DNA formation.

47 erein, we have investigated the formation of sticky DNA from plasmid monomers and dimers; sticky DNA

48 , linking number determinations confirm that sticky DNA has an important consequence in vivo.

49 These results suggest that the role of sticky DNA in FRDA may be the sequestration of transcrip

50 C-containing plasmids showed the presence of sticky DNA in vivo and, thus, serves as an important bri

51 play an important role in the monomer-dimer-sticky DNA intracellular intercon-versions.

52 Sticky DNA is a single long GAA.GAA.TTC triplex formed i

53 Sticky DNA is formed by the association of two purine.pu

54 Sticky DNA is formed in plasmids by the association of t

55 sticky DNA from plasmid monomers and dimers; sticky DNA is formed only when two tracts of sufficientl

56 Hence, R.R.Y triplexes and/or sticky DNA may be involved in the etiology of FRDA.

57 To evaluate the effect of sticky DNA on transcription, in vitro transcription stud

58 cells showed that the in vivo properties of sticky DNA play an important role in the monomer-dimer-s

59 GA.TCC interruptions formed triplexes and/or sticky DNA similar to the uninterrupted repeat sequence.

60 ical density, repressed the formation of the sticky DNA structure, thereby restoring the expected pos

61 nal inhibition was observed not only for the sticky DNA template but also another DNA molecule used a

62 When a gel-isolated sticky DNA template was transcribed, the amount of full-

63 ts into our understanding of the capacity of sticky DNA to inhibit transcription and thereby reduce t

64 Thus, the sticky DNA triplex exists and functions in living cells,

65 r mechanism of transcriptional inhibition by sticky DNA was a sequestration of the RNA polymerases by

66 e indirect (inverted) repeat orientation, no sticky DNA was observed.

67 e sequence requirements for the formation of sticky DNA were evaluated in Escherichia coli plasmid sy

68 TTC)(n) (where n = 176 or 80) readily formed sticky DNA with (GAAGGA.TCCTTC)(65) cloned into the same

69 The triplex (sticky DNA) adopted by the long repeat sequence also eli

70 winding elements, tetraplexes, triplexes and sticky DNA) are described.

71 mation of non-B DNA structures (triplexes or sticky DNA), the formation of a persistent DNA x RNA hyb

72 adopts non-B DNA structures, (triplexes and sticky DNA).

73 d two repeat tracts to adhere to each other (sticky DNA).

74 FRDA) expanded GAA.TTC sequence, which forms sticky DNA, are prone to form dimers compared with monom

75 Sticky DNA, based on R.R.Y triplexes, was found at the e

76 ), which is ubiquitous in eukaryotes, formed sticky DNA, but shorter sequences of 10 or 20 repeats we

77 AGGA.TCCTTC)(65) repeat, which does not form sticky DNA, did not inhibit in vitro transcription, as e

78 ize non-B DNA conformations (i.e. triplexes, sticky DNA, flexible and writhed DNA, slipped structures

79 TC)65, also found in intron 1, does not form sticky DNA, inhibit transcription, or associate with the

80 A novel DNA structure, sticky DNA, is described for lengths of (GAA.TTC)n found

81 A novel type of unusual DNA structure, sticky DNA, was previously found in the expanded GAA.TTC

82 To elucidate the behavior of sticky DNA, we introduced various extents of GGA.TCC int

83 the dumbbell-shaped plasmid in our model for sticky DNA.

84 oli to evaluate the in vivo role, if any, of sticky DNA.

85 (where n = 126, 159, and 222 bp) also formed sticky DNA.

86 locus but is nonpathogenic and does not form sticky DNA.

87 of interruptions to inhibit the formation of sticky DNA.

88 TCC interruptions abolished the formation of sticky DNA.

89 ramolecular DNA.DNA-associated region of the sticky-DNA conformation formed by long GAA.TTC repeats.

90 ptake, decreased growth rate, and unhygienic sticky droppings adhering to chickens and floors of the

91 The number of birds with adhering sticky droppings is drastically reduced.

92 e hair on the balls, Smooth/Valentino balls, Sticky/Einstein balls, and Asymmetric/Punk balls, which

93 "Sticky" electrostatic interactions may have important co

94 ation of the three different tiles and three sticky end association strategies.

95 son-Crick base-pairs and a two-nucleotide 5'-sticky end at each end of the duplex.

96 the interior of the frame through prescribed sticky end interactions.

97 DNA target hybridizes this signal probe, the sticky end remains free to hybridize another target lead

98 ally modified with DNA bearing complementary sticky end sequences.

99 on-Crick complementary single-stranded DNA ("sticky end") linking strategies.

100 l are the free energies of ligation for each sticky end, which can be estimated by the calculator fro

101 DNA template adjacent to the gene, leaving a sticky end.

102 methylene blue (a redox moiety) label and a "sticky end." When a DNA target hybridizes this signal pr

103 inside aquafoldamers can be created via the "sticky" end-mediated formation of 1D chiral helical stac

104 bility and cooperativity of a network of DNA sticky-end associations could lead to greater control ov

105 cifically designed arm lengths and intertile sticky-end interactions can be used to form sophisticate

106 e multiple cloning site via either blunt- or sticky-end ligation not only serves as a highly efficien

107 Free energies of sticky-end mismatches are also calculated for determinin

108 shared-stem design for the LNA-MB to prevent sticky-end pairing.

109 modifications (1) confirms the importance of sticky-end stacking, (2) confirms the identity of the in

110 work, we demonstrate for the first time that sticky ended dimers are not a prerequisite for alpha-hel

111 f such nanofibers has been the formation of "sticky ended" dimers through careful selection of electr

112 ate configurations, for example, homodimers, sticky-ended assemblies, and antiparallel arrangements.

113 aspartate to stabilize the triple helix in a sticky-ended assembly.

114 ination of synthetic stable branched DNA and sticky-ended cohesion has led to the development of stru

115 hnology combines branched DNA junctions with sticky-ended cohesion to create self-assembling macromol

116 embled into objects and networks directed by sticky-ended cohesion.

117 uous arrays facilitated by sequence-specific sticky-ended cohesion.

118 produce well-ordered 2D periodic arrays via sticky-ended cohesion.

119 Sticky-ended DNA duplexes can associate spontaneously in

120 at the modified base, and the other across a sticky-ended DNA junction.

121 in charged pairs, and is inspired by similar sticky-ended fibrillation designs applied in DNA and coi

122 ion electron microscopy indicate that these "sticky-ended" fragments self-assemble via intermolecular

123 and of DNA composed entirely of concatenated sticky ends and that binds to four local neighbours duri

124 re is also a logical equivalence between DNA sticky ends and Wang tile edges.

125 tent state in which two unbound chromodomain sticky ends appear exposed.

126 ends are flanked by a pair of dyes; when the sticky ends are disrupted, the dyes separate, and the fl

127 Those sticky ends are flanked by a pair of dyes; when the stic

128 Complementary sticky ends associate with each other preferentially and

129 nucleosomal distance, suggesting that the CD sticky ends bridge nearby methylated nucleosomes.

130 on an edge adjacent to the binding site; the sticky ends can be disrupted if the protein binds with s

131 The sticky ends cohere with one another, so the molecules fo

132 irections of propagation associated with the sticky ends do not share the same plane, but extend to f

133 ation with complementary single-stranded DNA sticky ends is increasingly used for guiding the self-as

134 The strength of the sticky ends is readily varied, so that the ability of th

135 ive adsorption properties of the two 12-base sticky ends of the DNA molecules to partially immobilize

136 The two DX molecules are also joined by sticky ends on an edge adjacent to the binding site; the

137 ary the number of linkers, the length of the sticky ends on the linker, and linker architecture and m

138 nd the generation of unique, non-palindromic sticky ends permits the formation of seamless junctions

139 r backbone, self-complementary "palindromic" sticky ends readily form intraparticle hairpins and loop

140 Efficient NHEJ of sticky ends requires the Ku70 and Ku80 proteins and the

141 Sticky ends thus created are uniform across the assembly

142 chieved using reactants with non-palindromic sticky ends to maximize specificity.

143 ranched DNA molecules are linked together by sticky ends to produce objects, periodic arrays, and nan

144 , we find that the backbone that tethers the sticky ends to the surface can have a significant impact

145 -assembly processes, with complementary DNA "sticky ends" as one of the most notable examples.

146 Complementary 'sticky ends' form specific inter-particle links and repr

147 the solution an oligonucleotide duplex with 'sticky ends' that are complementary to the two grafted s

148 tural units are programmed by the design of 'sticky ends' that associate according to Watson-Crick co

149 GT/-3', producing four base 3'-OH overhangs (sticky ends).

150 sembly of cohesive single-stranded segments (sticky ends).5, 6 Methods that exploit the sequence addr

151 Functionalized with DNA with single-stranded sticky ends, patches on different particles can form hig

152 For our 11 base "sticky ends," the limit is 73 distinct sequences with no

153 ell-structured branched DNA motifs tailed by sticky ends.

154 ity, was also constructed by the addition of sticky ends.

155 ze on a nucleosome, generating two vacant CD sticky ends.

156 rmation of the 12 base-pair single-stranded "sticky" ends of mature lambda DNA.

157 f the duplex, thus forming the 12-base-pair "sticky" ends of the mature genome.

158 e combination of branched DNA molecules and 'sticky' ends creates a powerful molecular assembly kit f

159 the intermolecular contacts are directed by 'sticky' ends.

160 s and is analogous to the "reprogramming" of sticky-ends displayed on the DNA tiles.

161 the number and the relative position of DNA sticky-ends play a significant role in the stability of

162 These had "sticky-ends" to promote the formation of long fibers.

163 e the extraordinary ability to prevent their sticky feet from fouling while running on dusty walls an

164 f slowpoke expression in muscle, whereas the sticky-feet phenotype arises from a lack of expression i

165 defect of slowpoke null mutants but not the sticky-feet phenotype.

166 t but cool light or a heat pulse, exhibit a "sticky-feet" phenotype.

167 es from water exiting between rakers, or (3) sticky filters that retain particles encountered by a hy

168 integrins along the leading edge suggests a "sticky fingers" mechanism to probe for new adhesion site

169 eal the molecular basis of the formation of 'sticky fingers' at the leading edge of migrating cells a

170 ated with growing actin filaments that form 'sticky fingers' to sense extracellular matrix and guide

171 ions, thus corresponding to the tips of the 'sticky fingers.' Formation of the complex requires talin

172 normal gap/overlap effect, consistent with 'sticky fixation'.

173 e transiently expressed an inducible mutant 'sticky' flagellin are adhered to a volume of glass beads

174 The Sticky-flare is capable of entering live cells without t

175 On recognition, the Sticky-flare transfers a fluorophore-conjugated reporter

176 SNA) gold nanoparticle conjugate, termed the Sticky-flare, which enables facile quantification of RNA

177 rthermore, we investigate the application of Sticky-flares for tracking transcripts that undergo more

178 Fly density was monitored by use of sticky fly-papers hung in sentinel compounds.

179 ulation tools that are not too 'fat' or too 'sticky' for atomic scale assembly is an important challe

180 that these GTPases antagonistically regulate STICKY functions.

181 mperature-sensitive allele of the Drosophila sticky gene and we show that sticky/citron kinase is req

182 sticky genetically interacts with Argonaute 1 and sticky

183 cal process we cover is involved in building sticky glucan matrix to establish cariogenic biofilms by

184 catalyze the sucrose-dependent synthesis of sticky glucan polymers that, together with glucan bindin

185 t adhesive lamination process enabled by the sticky GO/PEDOT film.

186 f hard spheres with short-range attraction ("sticky hard spheres").

187 Analyzing randomly generated, compact sticky homopolypeptide conformations constructed in gene

188 a pivotal role in aggregation by acting as a sticky hook in dimer assembly.

189 ct family, we review mirid interactions with sticky hosts, including their adaptations (behavioral, m

190 This fact implies that packing defects are "sticky" in a way that decisively contributes to determin

191 as a proxy for the distribution of variably sticky information in a population.

192 The sticky interconnect can greatly simplify the fabrication

193 ility to act as a temporary parking spot for sticky intermediates by binding many motifs; and an unfo

194 As over-sticky intermediates occasionally stall the catalytic un

195 The solvent extract of the sticky material from the whole fresh fruit and pure isol

196 The sticky material on its surface, consumed as part of the

197 Chemical characterization of sticky material on tomatillo fruits yielded five new suc

198 plasma, vWf apparently binds the inherently sticky membrane-binding motif, preventing nonspecific in

199 fic binding within the relatively adhesive, 'sticky' microenvironment of the brain and brain tumors i

200 Accumulation of thick, sticky mucus is a hallmark of the genetic disease cystic

201 are known to result in abnormally thick and sticky mucus; however, why mucus accumulates in CF is st

202 increasing the probability of encounter with sticky, mucus-covered surfaces such as the oral roof, gi

203 se phenotypes are an indirect consequence of sticky mutant cell-cycle defects or whether they define

204 y genetically interacts with Argonaute 1 and sticky mutants exhibit context-dependent Su(var) and E(v

205 We report that the mouse sticky mutation, which causes cerebellar Purkinje cell l

206 Simultaneous depletion of septins and Sticky not only disrupted MR formation but also caused e

207 ikingly, small polar uncharged molecules are sticky on the protein surface, whereas charged small mol

208 with nonadhesive-hydrophobic and hydrophilic-sticky opposite surfaces.

209 iers that direct particle-laden water to the sticky oral roof, where particles are retained as water

210 microscopy showed details of a thin, highly sticky, organic conditioning layer between these patches

211 However, sticky packing defects are typically not conserved acros

212 Using a minimal model of ill-fitting, sticky particles, we demonstrate robust fiber formation

213 Modeling studies suggest the presence of sticky patches on the surface of the N-terminal domain t

214 otein-ligand-1 (PSGL-1) is found in discrete sticky patches whereas LFA-1 is expressed over the entir

215 Characterization of the sticky peel (pe) mutant of tomato (Solanum lycopersicum)

216 Mutations in cpsQ suppressed the sticky phenotype of scr mutants.

217 gical and agricultural implications of mirid-sticky plant systems.

218 well-documented examples of insects that are sticky-plant specialists.

219 Sticky plants are widespread and often entrap and kill s

220 Sticky plants-those having glandular trichomes (hairs) t

221 nown group of arthropods that specializes on sticky plants.

222 ly as a plant-provided food for predators on sticky plants.

223 rgy crystal faces on their apexes act as the sticky points causing the particles to join in the ends.

224 ilizes stainless steel screens coated with a sticky polydimethylsiloxane coating for collecting LVPCs

225 d through self-assembly of single-component "sticky" polymer-grafted nanoparticles.

226 tric field from a non-aqueous suspension of 'sticky' polymeric colloidal particles with a controlled

227 in communities where the cells have secreted sticky, polymeric compounds that allow them to attach to

228 As a contrast, the particles in sticky pores are microscopically active by showing limit

229 y caused by the heterogeneous environment in sticky pores, is the main reason for macroscopically slo

230 eside in macromolecular complexes with other sticky proteins due to molecular crowding.

231 via the carbonization of natural gelatinized sticky rice to probe the underlying oxygen electrocataly

232 Rheological data also show a sticky Rouse-like relaxation at long times due to collec

233 Moreover, we have introduced a 'sticky' sequence onto a chemically synthesized aptamer w

234 Sticky situation: the differentiation of mesenchymal ste

235 Newborn mutant mice have shiny, taut, and sticky skin without whiskers.

236 In its simplest version, this binary sticky sphere model features attraction only between S a

237 trap was defined as the radius of a passive "sticky" sphere that would intercept the same number of f

238 Capture silk is the sticky spiral in the webs of orb-weaving spiders.

239 acromolecule, such as a protein, through two sticky spots.

240 the Drosophila melanogaster CIT-K orthologue Sticky (Sti) does not require interaction with RhoA to l

241 ion and analysis of a novel Drosophila gene, sticky (sti), essential for cytokinesis in all fly proli

242 Here we show that Sticky (Sti), the Drosophila ortholog of the contractile

243 cs were developed to ensure that seeding of "sticky" stromal cells did not foul the electrode and com

244 )(150) (450 bp) readily adopted the X-shaped sticky structure; however, this structure has never been

245 the pKa values found for kcat/KM for the non-sticky substrate 2-hydroxy-2,4-pentadienoate and by dire

246 vs pH for the 10(4)-fold more reactive, but sticky substrate 2a [(kcat/Km)max = 3.9 x 10(6) M-1 s-1]

247 K(d apparent) (4.7) indicates that P2C is a sticky substrate.

248 te (k2 = 1.1 s(-1)), making Cdk2-pTpY/CycA a sticky substrate.

249 ce titrations demonstrates that AIB is not a sticky substrate.

250 rains protein evolution, whereby residues in sticky surface patches are more conserved than those fou

251 icle transport, food particle encounter with sticky surfaces, and inorganic particle rejection.

252 her words, high abundance proteins have less sticky surfaces.

253 We were able to develop a CL-activated "sticky tag" that converts the low CL signal into a stabl

254 s well as with alpha2-heme like a molecular "sticky tape" with the last 3-4 carbon atoms sticking out

255 when being used as a conductive double-sided sticky tape.

256 vity, as signified by a lower latency in the sticky-tape removal test.

257 minal filament, animals undergo the modified sticky-tape test (MST) on post-operative days 1, 3, 7 an

258 The modified adhesive removal (sticky-tape) test is an assessment of somatosensory dysf

259 ow to conduct the modified adhesive removal (sticky-tape) test.

260 quantities of "DNA stars" with three or four sticky terminals, mimicking molecules with controlled li

261 available Web-based ligation calculator, NP-Sticky, that predicts product distribution for given rea

262 g their mechanical properties and remaining "sticky," the tapes can exhibit new properties derived fr

263 However, because dehydrons are sticky, they constitute targets for inhibitor design.

264 ased viscosity is obtained, which turns into sticky thin films upon casting.

265 fied at the termini and renders the termini "sticky" to further self-assemble into collagen-like nano

266 ep their feet clean while walking about with sticky toes has remained a puzzle until now.

267 ter exhaust dust and horizontal and vertical sticky traps to collect planter operation-generated dust

268 etween the ability of a plasmid to adopt the sticky triplex conformation as assayed in vitro and its

269 ishes, resulting in the surface exposure of "sticky" type II collagen and thus predisposing the vitre

270 motility of EC, which allows EC to move on a sticky underground during vessel remodeling.

271 by revealing that megakaryocytes and their "sticky" wound-healing progeny, platelets, are important