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1 e co-stimulatory receptor ICOS (inducible co-stimulator).
2 hile undergoing implantation of a deep brain stimulator.
3 10 years after implantation of an epiretinal stimulator.
4 orylated tau in the presence of an autophagy stimulator.
5 o treatment with an electrical carotid sinus stimulator.
6 fingertips using a custom-made rotating drum stimulator.
7 mulation techniques, such as the vagus nerve stimulator.
8 Both BAY compounds are sGC stimulators.
9 remely sparse and yet remarkably capable CTL stimulators.
10 l for automated programming of basal ganglia stimulators.
11 hibitors of transcription into gene-specific stimulators.
12 sis of astrocytomas might be blocked by PKCe stimulators.
13 ing molecules interferon (IFN)-beta promoter stimulator 1 (IPS-1), IFN regulatory factor (IRF) 3, and
14 equired the adaptor protein IFNbeta promoter stimulator 1 (IPS-1, MAVS) and could be functionally unc
17 sing NS3/4A and TLR3/MyD88/IFN-beta promoter stimulator 1(-/-) mouse embryonic fibroblasts completely
18 ficiently cleaves TRIF and IFN-beta promoter stimulator 1, adaptors for TLR3 and the RLRs, respective
19 sponse gene 88 (MyD88) and IFN-beta promoter stimulator-1 signaling, indicating a common pathway inhi
20 (PKC) pathways, while treatment with the PKC stimulator 12-O-tetradecanoylphorbol-13-acetate restored
23 armacologic long-term treatment with a NO-GC stimulator altered auditory nerve responses but did not
24 y reveals that IL-33 acts as a potent immune stimulator and a hepatoprotective cytokine in acute vira
25 atumomab (CD3 x CD19), acting both as T cell stimulator and CLL depletion agent, and human rIL-2.
26 on between expression of inducible T-cell co-stimulator and induction of virus-specific antibodies in
28 ing process (e.g., testing new cytokines, co-stimulators and so on) can now be directly compared with
29 pha-GalCer) represents a new class of immune stimulators and vaccine adjuvants that activate type I n
30 The co-stimulators ICOS (inducible T cell co-stimulator) and CD28 are both important for T follicular
31 tivated transcutanously using a programmable stimulator, and the resultant finger flexion joint angle
32 ulse trains, or pulses from an eel-triggered stimulator, applied to a prey muscle preparations result
38 resolves the longstanding question of where stimulators bind and provides a path forward for drug di
43 We have assessed the role of B lymphocyte stimulator (BLyS) and its receptors in the germinal cent
46 omeostasis and tolerance is the B-lymphocyte stimulator (BLyS), also referred to as the B-cell activa
47 ion-inducing ligand (APRIL) and B-lymphocyte stimulator (BLyS), are important for the survival, proli
48 ction of growth factors such as B lymphocyte stimulator (BLyS; also known as "B-cell factor belonging
50 design and fabrication of a micro-scale cell stimulator capable of simultaneously providing mechanica
51 roblastoma cells with heat shock or the HSF1 stimulator celastrol increased TTR transcription in para
52 allogeneic mature moDCs are highly efficient stimulator cells, in the presence of exogenous IL-15, fo
54 administered under general anesthesia, and a stimulator coil consisting of 2 individual cone-shaped c
56 photolyzable diazirine derivative of a novel stimulator compound, IWP-051, and MS analysis, we locali
57 e sGC show clinical promise, but where these stimulator compounds bind and how they function remains
58 nduced depression, suggesting that microglia stimulators could serve as fast-acting anti-depressants
59 n's disease (PD) implanted with a deep brain stimulator (DBS) to test the hypothesis that the beta wa
63 ith acute HCV infection; inducible T-cell co-stimulator expression correlates with production of HCV-
68 diverse reverse transcriptases can be strong stimulators for slippage at slippage-prone template moti
71 lass of compounds (soluble guanylate cyclase stimulators), has been shown in previous clinical studie
76 oliferation, activation, inducible T-cell co-stimulator (ICOS) expression and interleukin-21 (IL-21)
79 intain high level expression of inducible co-stimulator (ICOS), which in turn was required for TFR ce
81 type within many hormone-related tumors (as stimulator in bladder, kidney and lung metastases vs as
83 apabilities, Myo9b(-/-) DCs were poor T cell stimulators in vitro in a three-dimensional collagen mat
87 NF family (BAFF), also known as B lymphocyte stimulator, is a ligand required for the generation and
88 KAP protein, MDI that recruits a translation stimulator, La-related protein (Larp), to the mitochondr
89 all RMSs tested, whereas inducible T-cell co-stimulator ligand (ICOS-L; alias B7H2) was expressed by
90 of intracellular ICOSL (inducible T-cell co-stimulator ligand, also known as ICOSLG) to the B-cell s
91 iogenesis-targeting moieties with angiogenic stimulator-loaded NPs could be incorporated into effecti
92 nitoring with a qualitative peripheral nerve stimulator makes it impossible to determine the actual t
94 insulinotropic polypeptide (GIP) is a strong stimulator of adipogenesis and may play a role in the de
96 mtClpX, therefore, is a widely conserved stimulator of an essential biosynthetic pathway and uses
99 oxy-9Z-octadecenoic acid (12,13-diHOME) is a stimulator of BAT activity, and that its levels are nega
101 suggest that the RSPO family is an important stimulator of beta-catenin activity in many human tumors
102 2+) sensor with a key role as a feed-forward stimulator of beta-cell Ca(2+) signals that enhance GSIS
104 Surprisingly, JWU-A021 is also a potent stimulator of Ca(2+) influx through TRPA1 cation channel
105 sab (cfos) as a potent miR-101a target gene, stimulator of CM proliferation, and inhibitor of scar ti
108 ndria-specific lipid cardiolipin is a potent stimulator of Drp1 GTPase activity, as well as of membra
110 entifies JWU-A021 to be an especially potent stimulator of glucagon-like peptide-1 (GLP-1) secretion
115 We have also demonstrated that codelivery of stimulator of IFN genes (STING) agonists stimulates immu
116 Cyclic dinucleotides (CDNs) are agonists of stimulator of IFN genes (STING) and have potential as va
118 deficiencies in IFN-alpha/beta signaling or stimulator of IFN genes (STING) exhibit exacerbated neur
120 ocalized with DNA and the signaling molecule stimulator of IFN genes (STING) in the cytoplasm only in
123 II/IFNaR together with deficiency in either stimulator of IFN genes (STING) or absent in melanoma 2
124 lammasome, on the functional output from the stimulator of IFN genes (STING) pathway is poorly unders
128 MP-AMP, which binds to the signaling adaptor stimulator of IFN genes (STING) to induce IFN-beta expre
130 We showed previously that CDG activates stimulator of IFN genes (STING)-dependent IFN-I producti
134 nostimulatory DNA directly and activated the stimulator of IFN genes -TANK-binding kinase 1 - IFN reg
135 dency on IFI16, cyclic GMP-AMP synthase, and stimulator of IFN genes for type I IFN induction by a pa
136 analyses have revealed a major role for the stimulator of IFN genes pathway (STING pathway), which s
143 fect is partially replicated in mice lacking stimulator of IFN genes, a mediator of cellular response
144 intracellular DNA triggers activation of the stimulator of IFN genes-dependent IFN-stimulatory DNA (I
146 nt with gemcitabine HCl resulted in enhanced stimulator of IFN genes-mediated production of IFN-beta
148 an enhancer of GSIS in vivo and as a direct stimulator of insulin-independent glucose uptake is not
150 Activation of the cyclic dinucleotide sensor stimulator of interferon (IFN) genes (STING) is critical
151 g the cyclic GMP-AMP synthase (cGAS) and the stimulator of interferon (IFN) genes (STING), two crucia
152 3'-cGAMP can bind the adaptor protein STING (stimulator of interferon [IFN] genes) to activate the pr
153 esponses is tumor-derived DNA, sensed by the stimulator of interferon gene (STING) pathway and drivin
154 he innate immune response that activates the stimulator of interferon genes (STING) adaptor and induc
159 tosolic DNA-sensing pathways that signal via Stimulator of interferon genes (STING) mediate immunity
160 s the second messenger cGAMP to initiate the stimulator of interferon genes (STING) pathway and subse
162 A and produces cGAMP, which in turn binds to stimulator of interferon genes (STING) to activate IFN-I
164 messenger that activates the adaptor protein stimulator of interferon genes (STING) to induce type I
165 a is a vita-PAMP, engaging the innate sensor stimulator of interferon genes (STING) to mediate endopl
166 transmembrane protein 173 (TMEM173) encoding stimulator of interferon genes (STING) underlie a recent
168 Here, we report that a natural agonist of stimulator of interferon genes (STING), 2'3'- cyclic gua
169 the association of IRF3 with the ER adaptor, stimulator of interferon genes (STING), as well as subse
171 nced a candidate gene, TMEM173, encoding the stimulator of interferon genes (STING), in this patient
172 pon activation, which binds to and activates stimulator of interferon genes (STING), leading to IFN p
173 binds dsDNA via HIN200 domains and activates stimulator of interferon genes (STING), leading to TANK
175 gh mitosis or loss of pattern recognition by stimulator of interferon genes (STING)-cGAS impaired int
176 , as well as induction of AIM2-dependent and stimulator of interferon genes (STING)-dependent autopha
177 nto the cytosol that intrinsically activates stimulator of interferon genes (STING)-dependent cytokin
178 d to down-regulate the NF-kappaB pathway and stimulator of interferon genes (STING)-dependent cytokin
186 NA activated the downstream STING-TBK1-IRF3 (stimulator of interferon genes - tank-binding kinase 1 -
187 rt on a cyclic GMP-AMP adjuvant, the natural stimulator of interferon genes agonist, providing eviden
188 against tumors was defective in mice lacking stimulator of interferon genes complex (STING), but not
189 One such sensor referred to as STING (for stimulator of interferon genes) has been found to be sem
192 -cGAMP), the natural agonist of STING (i.e., stimulator of interferon genes) or after infection with
193 indings that have pointed towards the STING (stimulator of interferon genes) pathway of cytosolic DNA
194 GAS-STING (cyclic GMP-AMP synthase linked to stimulator of interferon genes) pathway, leading both to
195 was TLR9-independent but dependent on STING (stimulator of interferon genes), a cytosolic adaptor rec
197 we show that UV radiation potentiates STING (stimulator of interferon genes)-dependent activation of
198 TRIM29 induces K48-linked ubiquitination of Stimulator of interferon genes, a key adaptor in double-
199 a focus on complement, the adapter molecule Stimulator of Interferon Genes, natural killer cells, my
200 ng, as exemplified by the recently described stimulator of interferon genes-associated vasculopathy w
201 ic activation of the cyclic GMP-AMP synthase-stimulator of interferon genes-TANK-binding kinase-inter
202 is secreted by white cells only, is a potent stimulator of macrophage chemokinesis, whose activity is
203 cute exercise and identified VEGF-A as a key stimulator of Mdm2 phosphorylation on Ser(166) (p-Ser166
207 ess, epidermal growth factor (EGF), a growth stimulator of PCa cells, could only increase Cdc25C prot
209 embolic pulmonary hypertension, riociguat, a stimulator of soluble guanylate cyclase, has proven effi
211 ioblastomas, represents the first documented stimulator of TGF-beta1-3 translation in vitro and in vi
212 ociated DYRK1A kinase has been reported as a stimulator of the developmentally important Hedgehog (Hh
214 h in mice treated with cyclosporine, a known stimulator of the HCM response, and compound VM/RC heter
215 e that binds to chromosomal DNA; ParB is the stimulator of the ParA ATPase and specifically binds to
216 s, suggests that IL-33 might be an important stimulator of tissue-localized loss of normal Treg cell
219 The aim was to determine whether leucine, a stimulator of translation initiation and skeletal muscle
220 nstrate that Chi3l1 is a multifaceted immune stimulator of tumor progression and metastasis whose ela
221 -function mutation in TMEM173, which encodes stimulator of type I IFN gene (STING), in the affected i
223 ically, downregulated expression of IL-33, a stimulator of type II innate lymphoid cells, in lung epi
225 n Ag during the maturation phase were better stimulators of Ag-specific MHC class I-, but not class I
226 7BL/6 bone marrow-derived dendritic cells as stimulators of allogeneic Balb/c Foxp3 T cells, which al
228 Dietary lipids are one of the most effective stimulators of carotenoid absorption, but very limited d
229 tro, DLL4-deficient APCs were less efficient stimulators of CD4(+) T cell activation, metabolism, pro
230 provision of signals that can act as potent stimulators of dendritic cell maturation, as well as dir
232 retreatment, S1P and FTY720-P were effective stimulators of ECM synthesis, whereas ponesimod was inac
236 d 3) chitin and chitosan are relatively weak stimulators of inflammatory mediators from unprimed BMMP
237 in an antigen-dependent manner became potent stimulators of localized antigen-specific inflammatory r
238 ally expressed, including underexpression of stimulators of lymphocyte function and overexpression of
239 This identifies THs as potent endocrine stimulators of mitochondrial function in human epidermis
240 Specifically, we show that EVs are potent stimulators of MMP-9, IL-6, TGF-beta1 and induce the sec
243 isolated from C3H/HeJ mice were less potent stimulators of T lymphocyte proliferation and TH1/TH17 p
244 (TLR-9) in endosomes and are well described stimulators of the innate and adaptive immune system.
245 tigens at their cell surface that are potent stimulators of the innate immune response, and yet the c
246 ut screen to identify small molecular weight stimulators of the innate immune system revealed substit
247 (FSIGT) with the stimulator on and with the stimulator off on separate days in a randomized, double-
249 medication-off/stimulator-on, medication-on/stimulator-off and medication-on/stimulator-on condition
250 patients were studied in the medication-off/stimulator-off, medication-off/stimulator-on, medication
251 nous glucose tolerance test (FSIGT) with the stimulator on and with the stimulator off on separate da
253 Patients were randomized (1:1) to have the stimulator ON or OFF for 1 month and then the opposite f
254 ngers of one hand, and a neutral-temperature stimulator on the middle finger, all three fingers feel
257 edication-off/stimulator-off, medication-off/stimulator-on, medication-on/stimulator-off and medicati
258 TUs, and the same phytochemical can act as a stimulator or deterrent to different groups of OTUs.
259 atment of rats with the first-in-class NAMPT stimulator, P7C3-A20, prevented behavioral and histologi
260 t disease who underwent an upgrade from VVIR stimulator (pacemaker, PM) to cardiac resynchronization
261 ific DNA-binding ATPase, ParA, and an ATPase stimulator, ParB, which binds to the centromere-like loc
263 aches to target brain circuits via implanted stimulators placed in the brain or on cranial nerves.
268 rase-5 inhibitors, soluble guanylate cyclase stimulators, prostacyclin analogues, and prostacyclin re
273 polysaccharide (LPS) is a toxic inflammatory stimulator released from the outer cell membrane of Gram
274 rst-in-class soluble guanylate cyclase (sGC) stimulator riociguat was recently introduced as a novel
276 0(1/2) to 16(1/2) hours before testing), and stimulator settings were unchanged for a mean (median) o
280 n the nucleoid in the presence of the ATPase stimulator, SopB, which binds to the sopC site on the pl
282 dditionally, the hippocampal infusion of PKA stimulator Sp-cAMP reverts the effect of D1/D5 dopaminer
283 clathrin-coated pits and that physiological stimulators such as GPCR ligands induce ADAM17-mediated
284 the middle digit was lifted off the thermal stimulator, suggesting that tactile stimulation is neces
285 rats with a multi-directional, multi-whisker stimulator system to estimate receptive fields by revers
286 ion of TCR/CD3 genes, T cell co-receptors/co-stimulators, T cell activation and signal-transduction g
287 as STING, MITA, and TMEM173) is a type I IFN stimulator that is essential for host defense against DN
289 a non-invasive pulsed magnetic facial nerve stimulator that will increase CBF as a treatment of isch
290 Parkinson's disease and implanted deep brain stimulators that preclude functional magnetic resonance
292 ation of beads soaked in either an autophagy stimulator (Tunicamycin) or inhibitor (Hydroxychloroquin
293 resulting in the discovery of once daily sGC stimulator vericiguat (compound 24, BAY 1021189), curren
297 racellular signals, selective inhibitors and stimulators were used to suggest which isoforms play an
298 n and that amyloid/DNA composites are immune stimulators when injected into mice, leading to autoimmu
299 rations are then replayed via a multiwhisker stimulator while recording neuronal responses in the bar
300 riociguat, a novel soluble guanylate cyclase stimulator, would have beneficial hemodynamic effects in
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