ライフサイエンスコーパス: stomatin

1 gulates GLUT1-mediated glucose transport via stomatin.

2 3, flotillin-1 and -2, peroxiredoxin-2, and stomatin.

3 s overall approximately 20% similar to human stomatin.

4 ning these three components is equivalent to stomatin.

5 s a close homologue of the mammalian protein stomatin.

6 t does contain an orthologue of human band 7 stomatin, a protein known to oligomerize, associate with

7 In contrast, stomatin accelerated the desensitization rate of ASIC2 a

8 Moreover, stomatin altered the function of ASIC channels.

9 of the microstome to an inducer contained in stomatin, an exudate of the prey.

10 UNC-1 shows extensive homology to human stomatin, an integral membrane protein thought to regula

11 sterol and major raft proteins flotillin and stomatin and contain low levels of cytoskeleton, all cha

12 e switch is mediated by the membrane protein stomatin and is an evolutionary adaptation to vitamin C

13 Prohibitins, stomatins, and a group of plant defense response genes a

14 onserved in evolution and P. falciparum (Pf) stomatin appears to be a prokaryotic-like molecule.

15 ved in proliferation and cell cycle control, stomatins are involved in ion channel regulation, and th

16 Stomatins are members of a large protein family conserve

17 Human stomatin (band 7.2b) is a 31-kDa erythrocyte membrane pr

18 Stomatins belong to the band-7 protein family, a diverse

19 These data suggest that stomatin binds to and alters the gating of ASICs.

20 s report describes the cloning of the murine stomatin chromosomal gene, determination of its genomic

21 We found that stomatin co-immunoprecipitated and co-localized with ASI

22 There are five mammalian stomatin-domain genes, all of which encode peripheral me

23 ersity of signaling protein genes, including stomatin (Epb7.2), S100A5, Ddit3, Sirt2, CD81, Sdc2, Omp

24 Its product, podocin, is a new member of the stomatin family, which consists of hairpin-like integral

25 ing that these features are conserved in the stomatin family.

26 raft-associated integral membrane proteins (stomatin, flotillin 1, and flotillin 2), extracellular s

27 oncordance between the exon structure of the stomatin gene and the locations of three domains predict

28 The stomatin gene is encoded by seven exons spread over appr

29 s identify a novel and unusual member of the stomatin gene superfamily that interacts with the periph

30 be linked to the mechanosensitive channel by stomatin-homologous MEC-2.

31 In Caenorhabditis elegans, stomatin homologs interact with DEG/ENaC channels, which

32 Two stomatin homologs, MEC-2 and UNC-24, interact with the M

33 ng and characterization of a new and unusual stomatin homologue, human SLP-2 (stomatin-like protein 2

34 A second stomatin homologue, termed SLP-1, has been identified in

35 )-terminal hydrophobic domain found in other stomatin homologues and (unlike stomatin) is fully extra

36 Therefore, we asked whether stomatin interacts with and modulates the function of AS

37 Stomatin is a poorly understood integral membrane protei

38 Stomatin is an integral membrane protein found in lipid/

39 rom patients with hereditary stomatocytosis, stomatin is not linked to this disorder.

40 Mammalian stomatin is thought to interact with an as-yet-unknown i

41 und in other stomatin homologues and (unlike stomatin) is fully extractable from erythrocyte membrane

42 Whereas neither the central, stomatin-like domain of MEC-2 nor human stomatin retaine

43 onase-like MEC-6 and the cholesterol-binding stomatin-like MEC-2 proteins.

44 Here we examined the ability of stomatin-like protein 1 (STOML1) to modulate the proton-

45 Stomatin-like protein 2 (SLP-2) is a mostly mitochondria

46 ate that Parkin interacts with mitochondrial Stomatin-like protein 2 (SLP-2), which also binds the mi

47 romatography and tandem mass spectrometry as stomatin-like protein 2 (Stoml2), previously described a

48 T6) and one putative novel asthma risk gene, stomatin-like protein 2 (STOML2).

49 and unusual stomatin homologue, human SLP-2 (stomatin-like protein 2).

50 on), suppresses three phenotypes of neuronal stomatin-like protein deficiency as follows: volatile an

51 lone molecules, it has now been shown that a stomatin-like protein regulates a gap junction channel i

52 and functions synergistically with MEC-2 (a stomatin-like protein that regulates MEC-4(d)/MEC-10(d)

53 unc-1(dn) alters a stomatin-like protein that regulates unc-9 electrical si

54 Loss of the stomatin-like protein UNC-1, which is a regulator of UNC

55 A second stomatin-like protein, UNC-24, colocalizes with MEC-2 in

56 anically gated ion channels is controlled by stomatin-like protein-3 (STOML3), which is required for

57 re frequently associated with genes encoding stomatin-like proteins (slipins).

58 enome contains two paralogous genes encoding stomatin-like proteins (SLPs; AtSLP1 and AtSLP2) that ar

59 y that similar ion channels may be formed by stomatin-like proteins and DEG/ENaC proteins that are co

60 These neuronal stomatin-like proteins are putative chaperone proteins t

61 cate that modulation of DEG/ENaC channels by stomatin-like proteins is evolutionarily conserved and m

62 d ssu-1 is the first association of neuronal stomatin-like proteins sharing regulatory roles with a s

63 The neuronal stomatin-like proteins UNC-1 and UNC-24 play important r

64 The stomatin-like region of MEC-2 interacts with the intrace

65 e integral membrane protein MEC-2 contains a stomatin-like region that is highly conserved from bacte

66 Stomatin-like regions in other proteins may serve a simi

67 eract with the MEC-4 degenerin through their stomatin-like regions, which act as protein binding doma

68 Thus, like caveolin-1 and flotillin-1, a stomatin may also associate with non-clathrin coated, DR

69 channel subunit MEC-4 and channel-associated stomatin MEC-2 are specifically required for neural resp

70 We hypothesize that SLP-2 may link stomatin or other integral membrane proteins to the peri

71 es that are membrane raft associated, namely stomatin, paraslipin (previously SLP-2) and flotillin.

72 Loss of the stomatin/PHB/flotillin/HflK/C (SPFH) domain containing p

73 , as with the erythrocyte lipid raft protein stomatin, podocin is present in high-order oligomers and

74 Stomatin potently reduced acid-evoked currents generated

75 AtHIR proteins contain the stomatin/prohibitin/flotillin/HflK/C domain (also known

76 rug resistance proteins, and proteins of the stomatin/prohibitin/hypersensitive response family, sugg

77 d' form shows very leaky cells and the 32 kD stomatin protein is missing, although the gene is not mu

78 yed a greater association with flotillin and stomatin, proteins known to associate with sphingolipid-

79 dentified in nonerythroid tissues, and other stomatin related proteins are found in Drosophila, Caeno

80 MEC-2, a stomatin-related protein needed for touch sensitivity, i

81 ral, stomatin-like domain of MEC-2 nor human stomatin retained the activity of full-length MEC-2, bot

82 unc-24, named ssu-1(fc73) (for suppressor of stomatin uncoordination), suppresses three phenotypes of

83 To establish the identity of the signal, stomatin was fractionated by combinations of cation exch

84 Band 3 and stomatin, which reflect the bulk mass of erythrocyte DRM

85 phb1, Zm-phb2, Zm-phb3, and Zm-phb4), one to stomatins (Zm-stm1), and three to a gene implicated in p