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1 ed for baseline NIHSS score and thrombolysis stratum).
2 imilar difference was found across each race stratum.
3 muted blocks (block size of six) within each stratum.
4 lightly higher risk in the >/=400-microg/day stratum.
5 a nonstratified analysis and in the <55-year stratum.
6 nondirectional M6-LNs covering the entire M6 stratum.
7 age strata and 10% in the 46 years and older stratum.
8 Five clusters were identified in each age stratum.
9 ith radiocontrast administration within each stratum.
10 sidered for those in the low-mortality-score stratum.
11 w-energy context of the enclosing sandy silt stratum.
12 ntervention did not differ by BMI percentile stratum.
13 ated randomisation list was used within each stratum.
14 s of atherosclerosis in either postmenopause stratum.
15 the estradiol group in either postmenopause stratum.
16 ent effect behaves similarly across all risk stratums.
21 rticipants were included in the HIV-infected stratum (146 [20.5%] were culture positive) and 313 were
22 zation than with medical therapy in the CABG stratum (15.3% vs. 30.3%, p = 0.02), but not in the PCI
25 p=0.02), but not in the low-mortality-score stratum (17 [24%] of 72 vs 21 [20%] of 105; adjusted odd
27 received both aspirin and a thienopyridine (stratum 2), the benefit of rivaroxaban emerged during th
28 95; p=0.01), but not in those in the 5/x+x/x stratum (2.0 [2.5] vs 2.0 [2.3]; 1.03, 0.83-1.29; p=0.79
29 ced in children given montelukast in the 5/5 stratum (2.0 [2.7] vs 2.4 [3.0]; IRR 0.80, 95% CI 0.68-0
30 tion and medical therapy, either in the CABG stratum (26.1% vs. 29.9%, p = 0.41) or in the PCI stratu
32 in the younger participants (in the highest stratum: 3.30; 1.16-9.38; P = .003 for trend) but not in
33 was monotherapy in the high-mortality-score stratum (30 [48%] of 63 vs 64 [62%] of 103; adjusted HR
35 the usual care group in the invasive testing stratum ($8,619 vs. $ 10,734; p < 0.0001), whereas in th
37 3 strata based on screening CD4 count: >350 (stratum A), 201-350 (stratum B), and </=200 cells/microL
38 re 96%, 98%, 99%, and 91%, respectively, for stratum A; 100%, 98%, 98%, and 85%, respectively, for st
39 the >/=55-year stratum than in the <55-year stratum, a finding that could be explained by biology, s
41 we introduce a novel similarity measure, the stratum adjusted correlation coefficient (SCC), for quan
42 patients (95% CI, 96%-99%; difference in the stratum-adjusted Mantel-Haenszel proportions of -3.2%; 9
43 n stratum and for 7 days in the continuation stratum, after which patients resumed their regular aspi
44 ose of 100 mg) for 30 days in the initiation stratum and for 7 days in the continuation stratum, afte
45 association analyses were conducted in each stratum and meta-analyzed across all 15 discovery data s
47 r regression from 2 cohorts within each race stratum and then across race strata to produce overall e
48 emia peaked at 48% at week 8 in the high PTH stratum and then steadily decreased through month 12.
49 lculated for each urologist within each risk stratum, and the association between the physician-level
50 , including uncinate fasciculus and sagittal stratum as a control tract, were registered to the study
52 ; 100%, 98%, 98%, and 85%, respectively, for stratum B, and 84%, 92%, 93%, and 75%, respectively, for
53 ence of keratinocytes in layers close to the stratum basale, whereas keratinocytes from epidermal lay
54 rithm process that accounted for region, age stratum, baseline HPV DNA status, HPV 16/18 serostatus,
55 ve care compared with whites in any hospital stratum, but the odds of palliative care for both white
58 Functional groups based on habitat domain (stratum) caught the essential functional differences bet
59 r adjustment for age, gender, socio-economic stratum, city and other IgE levels (adjusted ORs: 2.17;
61 dings suggest that the Drosophila medulla M6 stratum contains diverse LNs that form repeating functio
62 showed that it shrunk the corneocytes in the stratum corneum (p<0.001) and the imaging of the skin ha
63 h quantity and spatial distribution of human stratum corneum (SC) lipids from samples collected in vi
66 solvents on the outermost layer of skin, the stratum corneum (SC), using polarization transfer solid-
67 ubstantially reduced drug diffusivity in the stratum corneum (the outermost epidermal layer), dominan
69 of interventions with partial removal of the stratum corneum after curettage and microdermabrasion an
70 heir estimated saturation doses in the upper stratum corneum allows one to distinguish between diffus
72 tion can effectively carry siRNA through the stratum corneum and deposit it at the lower epidermis/up
73 ely, a low permeability of siRNA through the stratum corneum and epidermis has significantly limited
74 lved in the physical barrier function of the stratum corneum and provide innate cutaneous host defens
75 to the cornified envelope) is present in the stratum corneum and retains the ability to form covalent
76 lid microneedles, providing microporation of stratum corneum and therefore enhancement of topical dru
77 elivery system that can permeate through the stratum corneum and viable epidermis and efficiently dep
78 within the polymer matrix, breach the skin's stratum corneum barrier and dissolve upon contact with s
80 on due to their ability to bypass the skin's stratum corneum barrier in a minimally-invasive fashion
81 We show that on breakdown of the epidermal stratum corneum barrier, type 2 and type 17 inflammatory
84 ansverse diffusivities of these compounds in stratum corneum by factors ranging from 250 to over 2000
86 ompromises permeability barrier homeostasis, stratum corneum cohesion, wound healing, and epidermal i
88 This concept is probed using excised human stratum corneum exposed to aqueous solutions of radiolab
90 f keratinocyte SerpinB2 is protection of the stratum corneum from proteolysis via inhibition of uroki
92 permeability barrier homeostasis and reduced stratum corneum hydration, we hypothesized here that epi
93 th ionic and uncharged, partition into human stratum corneum immersed in aqueous solutions to an exte
94 pidermal water loss, increased overt loss of stratum corneum in inflammatory lesions, and impaired st
97 anisotropic brick-and-mortar geometry of the stratum corneum is obtained using the commercial finite
98 trastructural analyses demonstrated abnormal stratum corneum lipid architecture in AD and IV HEEs, in
99 ed changes in skin properties and CCBAs from stratum corneum of healthy human subjects, providing a m
101 found in both interfollicular and follicular stratum corneum of lesional KP, which correlated ultrast
102 o compromised chelation of the metals in the stratum corneum of patients with atopic dermatitis.
103 strated notable topographical changes in the stratum corneum of skin permeated with CYnLIP that were
104 limited by their poor permeation across the stratum corneum of the skin and low penetration into the
107 The impact of the complex structure of the stratum corneum on transdermal penetration is not yet fu
109 The intercellular lipid matrix of the skin's stratum corneum serves to protect the body against desic
110 orneum in inflammatory lesions, and impaired stratum corneum thickening after phorbol ester treatment
111 markers (filaggrin and loricrin), increased stratum corneum thickness, and significantly reduced T-c
113 kin revealed hyperkeratosis and a disordered stratum corneum with an accumulation of neutral lipid dr
114 pended in water, facilitate adherence to the stratum corneum without subsequent intra-epidermal or fo
116 ecreased intercellular lipid lamellae in the stratum corneum, and aberrant keratinocyte differentiati
117 on through the external barrier of the skin, stratum corneum, and secure exposure to the viable skin
118 assessed in culture media and extracts from stratum corneum, epidermis and dermis after 24h, and the
119 ed that the viable epidermis, underlying the stratum corneum, is included as a potentially important
120 ng the integrity and barrier function of the stratum corneum, particularly during times of skin infla
121 e outermost skin barrier (referred to as the stratum corneum, SC) and subsequent catalytic generation
122 sed to effectively deliver siRNA through the stratum corneum, the major challenge is that this approa
123 Retinoids cause dyshesion and thinning of stratum corneum, thereby reducing hyperkeratosis that li
124 epidermal epithelium leading to a defective stratum corneum, which allows enhanced allergen penetrat
125 uantity of ultra long-chain ceramides in the stratum corneum, which play a key role in maintaining th
126 paired skin barrier function and a defective stratum corneum, with SerpinB2(-/-) mice showing increas
137 r the baseline antibiotic prescription rate, stratum (county), and potentially confounding patient an
141 posite outcome (n = 9002 events) in each CKD stratum for event rates per 100 person-years: eGFR>60 ev
142 in patients treated with warfarin in any CKD stratum for event rates per 100 person-years: eGFR>60 ev
144 ts versus 23.06% in NACC; in the 65-69-y age stratum, from 9.42% to 10.39% versus 34.62%; and in the
146 l as stronger staining of cathepsin B in the stratum granulosum of affected individuals than in that
147 esence of AQP5 at the plasma membrane in the stratum granulosum of both normal and affected palmar ep
148 del identified penetration of FLG+RMR to the stratum granulosum, the epidermal layer at which FLG def
155 men, with optimal-normal BP as the reference stratum, hazard ratios for CVD and CHD mortality risk fo
158 ommon adverse event reported was arthralgia (stratum I: 94 placebo and 114 anastrozole; stratum II: 3
159 t baseline T score at spine or femoral neck (stratum I: T score at least -1.0; stratum II: T score at
160 onate versus placebo for osteopenic women in stratum II randomly allocated to anastrozole (1 mg/day).
162 and Sept 30, 2010, 150 (58%) of 260 women in stratum II who had been randomly allocated to anastrozol
163 (stratum I: 94 placebo and 114 anastrozole; stratum II: 39 placebo/placebo, 25 placebo/risedronate,
164 oral neck (stratum I: T score at least -1.0; stratum II: T score at least -2.5 but less than -1.0; st
166 n in stratum I were monitored only; women in stratum III were all given risedronate (35 mg/week).
168 ole/placebo, and 34 anastrozole/risedronate; stratum III: 21 placebo/risedronate, 17 anastrozole/rise
169 I: T score at least -2.5 but less than -1.0; stratum III: T score less than -2.5 but greater than -4.
171 ecovered from a precisely dated 25.2-Myr-old stratum in the Rukwa Rift, a segment of the western bran
172 d megafauna at four sites within a 900 km(2) stratum in the UK-1 contract area, and at a site ~250 km
173 aminergic amacrine cells, by restricting the stratum in which exploring retinal dendrites stabilize,
174 (CAC) in reclassifying patients from a risk stratum in which statins are recommended to one in which
175 ring the previous year, whereas the expanded stratum included women with one to two previous losses,
176 incidence was as follows: in the 60-64-y age stratum, it ranged from 0% to 5.88% in the three populat
177 dritic arborization of CA2/3 basket cells in stratum lacunosum moleculare (33% of length, 29% surface
178 quitin and mitochondria accumulations in the stratum lacunosum moleculare (SLM) layer, without loss o
179 adiatum receive both signals, while those in stratum lacunosum-moleculare exclusively receive a gluta
180 litude, kinetically slow synaptic input from stratum lacunosum-moleculare interneurons, anatomically
182 ptic plasticity and dendritic development in stratum lacunosum-moleculare, thus impacting the integra
183 ifically targeted to dendritic spines in the stratum lacunosum-moleculare, which form synapses with p
186 onding to the lowest baseline PERG amplitude stratum (</=50%) and the reference stratum (>90%).
188 voked by MF stimulation in interneurons from stratum lucidum and stratum radiatum, but not in interne
189 of stratum radiatum interneurons, whereas in stratum lucidum interneurons only GABAergic responses we
190 , the simultaneous MF GABAergic responses of stratum lucidum interneurons, but not of stratum radiatu
191 lutamatergic LTD, which is known to exist on stratum lucidum interneurons, coexists in the same pathw
193 shown that the interneurons of the hilus and stratum lucidum receive this dual monosynaptic input on
194 item EuroQOL scale scores in the noninvasive stratum (mean change of 0.12 for FFRCT vs. 0.07 for usua
195 are; p < 0.0001); in the planned noninvasive stratum, mean costs did not differ when using an FFRCT c
204 e observed between incident hypertension and stratum of noise exposure at frequencies of 250 Hz, 1 kH
205 ess Nr4a2 and occupy a corticoid superficial stratum of the mesopallium, which is clearly comparable
206 ng the local False Discovery Rate (lFDR) per stratum, or partition, yields the most predictions acros
208 matostatin-expressing cells predominantly in stratum oriens and parvalbumin-expressing cells mostly i
209 ular-spiking interneurons in the hippocampal stratum oriens exhibit a form of long-term potentiation
210 Conversely, the exact same 5 ms pairing in stratum oriens potentiated both pathways, as did AP-burs
211 nd adenosine receptors counteracted unpaired stratum oriens potentiation following pairing in stratum
212 We extracted DNA from laser-microdissected stratum oriens tissue of cornu ammonis 2/3 (CA2/3) and C
213 ite membrane polarization of deep (closer to stratum oriens) and superficial (closer to stratum radia
214 ratified cells in the stratum pyramidale; in stratum oriens, HC PV cells were electrophysiologically
215 long-term potentiation (LTP) in hippocampal stratum oriens-alveus (O/A) interneurons requires co-act
218 s of interneurons within the hippocampal CA1 stratum oriens/alveus (O/A), with preferential innervati
219 mulation of distal dendritic branches within stratum oriens/alveus elicited fast Ca2+ transients, whi
220 ) and somatostatin (SOM) interneurons in CA1 stratum oriens/alveus fire during hippocampal theta and
223 s of the thalamus and anterior hypothalamus, stratum periventriculare of the optic tectum, dorsal teg
225 ty from up to 150 neurons in the hippocampal stratum pyramidale at approximately 1-mm depth within an
226 rdings from pyramidal cells and fast-spiking stratum pyramidale interneurons, we demonstrate that fas
227 orizontal, but not vertical, clusters in the stratum pyramidale, as revealed by both cell-type-specif
228 itude of gamma oscillations generated around stratum pyramidale, where basket cells selectively inner
232 asket cells and PV bistratified cells in the stratum pyramidale; in stratum oriens, HC PV cells were
239 of stratum lucidum interneurons, but not of stratum radiatum interneurons, displayed a Hebbian form
240 on potentiated MF glutamatergic responses of stratum radiatum interneurons, whereas in stratum lucidu
241 tex (ERC) and CA1 apical neuropil layer [CA1-stratum radiatum lacunosum moleculare (SRLM)] thickness,
242 sine release induced by focal stimulation in stratum radiatum of area CA1 in mouse hippocampal slices
244 ion in clustered gephyrin is detected in CA1 stratum radiatum of rTMS-treated anaesthetized mice.
245 itatory synapses on pyramidal neurons in the stratum radiatum rarely occurs in hippocampal area CA2.
246 Many interneurons in stratum lucidum and stratum radiatum receive both signals, while those in st
247 ed with preceding presynaptic stimulation in stratum radiatum specifically led to LTP of the paired p
248 sity on CA3 pyramidal cell apical dendrites (stratum radiatum) and an increase in the number of thorn
249 o stratum oriens) and superficial (closer to stratum radiatum) rat CA1 PCs during sharp-wave ripples.
250 throughout neuronal cell bodies, dendrites (stratum radiatum), and axons (fimbria), but not astrocyt
251 anization, especially in the hippocampal CA1 stratum radiatum, and also diminishes GABA-mediated syna
252 ion in interneurons from stratum lucidum and stratum radiatum, but not in interneurons from stratum l
253 form of GABAergic LTP, while interneurons of stratum radiatum, despite receiving this dual signaling,
260 cation system outperforms the standard three-stratum risk stratification system in predicting the ris
263 ower to detect associated SNPs by estimating stratum-specific false discovery rate (FDR), where strat
264 /=1.5 SD below age, sex, and education-based stratum-specific means on 2 or 3 CERAD assessments or, s
266 in condensation and margination in the upper stratum spinosum in lesional skin, suggesting impaired i
268 ediate, or high risk using the current three-stratum stratification system endorsed by the National I
269 rement of all current methods that determine stratum structure based on the comparison of gametologou
271 urred either before lumpectomy (prepathology stratum, TARGIT concurrent with lumpectomy) or after lum
272 mpectomy) or after lumpectomy (postpathology stratum, TARGIT given subsequently by reopening the woun
273 (P for difference = 0.015) in the >/=55-year stratum than in the <55-year stratum, a finding that cou
276 her a 5/5 or 5/x+x/x ALOX5 promoter genotype stratum, then randomly assigned (1:1) via a permuted blo
279 " of mortality was defined a priori for each stratum, to guide the interpretation of interim and fina
280 ; the number of preceding events (predictor, stratum variable); and the within-subject correlation (i
281 the 116 participants in the other secondary stratum was 1.03 (95% CI, 0-2.11; P = .53) and for the e
282 od of a reduction in the glucocorticoid-dose stratum was 2.39 times greater in the mepolizumab group
284 tified by eligibility criteria--the original stratum was restricted to women with one loss at less th
289 for AMI among total cholesterol (TC) 200-239 stratum were 5.3 (4.89, 5.71) for HCV-positive versus 4.
292 0.0001), whereas in the noninvasive testing stratum, when the cost weight of FFRCT was set to one-ha
293 es, we generated a 3D volume model of the M6 stratum, which revealed a retinotopic map for UV represe
294 re explained by body size, hunting modes and stratum, while niche size was influenced by hunting mode
295 ndomly assigned (1:1:1) in blocks of six per stratum with an interactive voice-response system to rec
296 nces between RNFL thicknesses of eyes in the stratum with most severely affected PERG (</=50%) and th
298 taking aspirin before the study (initiation stratum, with 5628 patients) or they were already on an
299 of dendronized PBI with one molecule in each stratum, with different intra- and interdimer rotation a
300 eptor neurons that project to the medulla M6 stratum, with relatively little known of this downstream
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