ライフサイエンスコーパス: streptogramin

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1 employed antibiotic classes tetracycline and streptogramin.

2 nhibitor madumycin II, an alanine-containing streptogramin A antibiotic, in the context of a function

3 The synergy in the binding of streptogramins A and B appears to result from a reorient

4 Streptogramins A is a class of protein synthesis inhibit

5 The crystal structure of Vat(D), a streptogramin acetyltransferase from a human urinary iso

6 in resistance phenotype and is mediated by a streptogramin acetyltransferase.

7 itors, the coproduction of type A and type B streptogramins, and the coregulated production and indep

8 The effect of the novel streptogramin antibiotic quinupristin/dalfopristin (syne

9 Streptogramin antibiotics are used clinically to treat m

10 this work will lead to the discovery of new streptogramin antibiotics that overcome previous limitat

11 ort a modular, scalable synthesis of group A streptogramin antibiotics that proceeds in 6-8 linear st

12 es resistance to macrolide, lincosamide, and streptogramin antibiotics.

13 asses such as aminocyclitols, phenicols, and streptogramins as treatment alternatives.

14 ed hypersensitivity to macrolide-lincosamide-streptogramin B (MLS(B)) antibiotics on strains either c

15 rains contained either macrolide-lincosamide-streptogramin B (MLSB) resistance genes encoded by erm(A

16 l target modification (macrolide-lincosamide-streptogramin B [MLSB] resistance; usually encoded by er

17 Streptogramin B analogs were designed that have an amide

18 target sites for macrolide, lincosamide, and streptogramin B antibiotics.

19 her antibiotics of the macrolide-lincosamide-streptogramin B group (MLS) is methylation of the 23S rR

20 ed antibiotics of the macrolide, ketolide or streptogramin B groups during 50 S subunit reconstitutio

21 ssibility of inducible macrolide-lincosamide-streptogramin B resistance (MLSBi).

22 stitutive or inducible macrolide-lincosamide-streptogramin B resistance phenotype (cMLS(B) or iMLS(B)

23 esistant (constitutive macrolide-lincosamide-streptogramin B resistance) demonstrated either a double

24 ing resistance to macrolide, lincosamide and streptogramin B type (MLS) antibiotics were previously i

25 e inducibly MLS (macrolide, lincosamide, and streptogramin B)-resistant organisms.

26 erring resistance to macrolides-lincosamides-streptogramin B, showing that differential inhibition of

27 red macrolides, lincosamides or analogues of streptogramin B.

28 tracycline, multidrug, macrolide-lincosamide-streptogramin, bacitracin, vancomycin, beta-lactam and a

29 The streptogramin class of antibiotics act to inhibit bacter

30 an L-lysine-derived pyridyl moiety found in streptogramin group B antibiotics that are used as part

31 oup A component of natural and semisynthetic streptogramin mixtures is a prerequisite for the strepto

32 The occurrence of resistance to the streptogramin quinupristin-dalfopristin in Enterococcus

33 The combination of the streptogramins quinupristin and dalfopristin was approve

34 PCR was performed to detect the streptogramin resistance genes vatD, vatE, and vgbA and

35 Known streptogramin resistance genes were absent in the majori

36 ifampin, but inducible macrolide-lincosamide-streptogramin resistance in a subset of CA-MRSA could be

37 ptogramin mixtures is a prerequisite for the streptogramin resistance phenotype and is mediated by a

38 rans, M. tuberculosis (macrolide-lincosamide-streptogramin resistance protein, MLSRP), and B. anthrac

39 virginiamycin may increase the potential for streptogramin-resistant E. faecium infection in humans.

40 in constitutive resistance to Er and type B streptogramins (Sg), proving that SgR does not require t

41 omise as an alternative to glycopeptides and streptogramins to treat serious infections due to resist

42 fers resistance to the macrolide-lincosamide-streptogramin type B (MLS) antibiotics through the methy

43 Since 1974, another streptogramin, virginiamycin, has been used at subtherap

44 New methods to chemically modify streptogramins would enable structural optimization to o

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