ライフサイエンスコーパス: stress response

1 ting an individual's ability to regulate the stress response.

2 entrations, a setting that triggers a strong stress response.

3 stores cell morphology and attenuates the ER-stress response.

4 ECD regulates the endoplasmic reticulum (ER) stress response.

5 edirection of carbon to neutral lipids and a stress response.

6 ranscriptionally activates ATP synthesis and stress response.

7 ant role in plant cell growth, division, and stress response.

8 ss, and indications for the genetic basis of stress response.

9 ion, histone acetylation, and the integrated stress response.

10 ociated with the innate immune and oxidative stress response.

11 in neuronal response, the immune system, and stress response.

12 ndent but involved the endoplasmic reticulum stress response.

13 bfunctionalization in growth/development and stress response.

14 an increased expression of genes involved in stress response.

15 to energy starvation but represents a common stress response.

16 insufficient to activate an unfolded protein stress response.

17 f U, Zn and Cu with a novel extracytoplasmic stress response.

18 s and contributes to the cellular integrated stress response.

19 tments indicating its possible role in plant stress response.

20 aB/IkappaB is used for system-wide oxidative stress response.

21 factor 4 (ATF4) as the main regulator of the stress response.

22 imental study and mechanistic model of shear stress response.

23 ers that exhibit dependencies on translation stress response.

24 presents a protective mechanism in the islet stress response.

25 activation as an immediate upstream event of stress response.

26 daptive changes that comprise the vertebrate stress response.

27 lation to vesicle transport, cell cycle, and stress response.

28 in mycothiol redox potential and compromised stress response.

29 nes, and have been linked to development and stress response.

30 implicating the involvement of an intrinsic stress response.

31 hypothalamic circuit coordinating the global stress response.

32 ces the importance of LrgAB to the S. mutans stress response.

33 TG6 mutants elicit an endoplasmic reticulum stress response.

34 portant to mediate ABA signaling and drought stress response.

35 tidine in correlation with the translational stress-response.

36 hanism to optimize the balance of growth and stress responses.

37 sential role for Jak1 in HSC homeostasis and stress responses.

38 lucagon-like peptide-1 (GLP-1) in modulating stress responses.

39 erties and a proteome-wide study of cellular stress responses.

40 ritical parts in development and disease and stress responses.

41 mportant signaling hub capable of initiating stress responses.

42 leads to fundamental discoveries related to stress responses.

43 iated with a wide range of developmental and stress responses.

44 kinase is a master regulator of replication stress responses.

45 tion during cell cycle progression or during stress responses.

46 levels are important for understanding plant stress responses.

47 ple processes, including differentiation and stress responses.

48 enotyping studies, and analysis of genotoxic stress responses.

49 nt of their involvement in the regulation of stress responses.

50 nism may be a general principle used in many stress responses.

51 nes involved in sulfur cycle, virulence, and stress responses.

52 e neurons is integral to the coordination of stress responses.

53 ontrol both cell fate regulators and abiotic stress responses.

54 rly (within 48 h) in vivo detection of plant stress responses.

55 condary metabolites, thereby tailoring plant stress responses.

56 d in proteins involved in biotic and abiotic stress responses.

57 redox homeostasis and coordinating cellular stress responses.

58 dysfunctional behavioural and neuroendocrine stress responses.

59 s unstable, high status actually exacerbates stress responses.

60 esses, including proliferation, survival and stress responses.

61 in sugar metabolism, flower development, and stress responses.

62 sing factor (CRF), an important modulator of stress responses.

63 this may contribute to global environmental stress responses.

64 ld sample were limited to abiotic and biotic stress responses.

65 t organism growth and development as well as stress responses.

66 important for plant growth, development, and stress responses.

67 droplets is a key aspect of some proteotoxic stress responses.

68 ic alterations which may relate to oxidative stress responses.

69 ction acts as a new checkpoint for oxidative stress responses.

70 tight mechanistic links between the cellular stress responses.

71 tant roles in various cellular processes and stress responses.

72 energy metabolism, organelle biogenesis and stress responses.

73 n (TAC) to determine SIRT5's role in cardiac stress responses.

74 ne expression profiles, and have compromised stress responses.

75 ribution of epigenetics to plant phenotypes, stress responses, adaptation to habitat, and range distr

76 lade level, implying that metal toxicity and stress response adaptations represent an important selec

77 s, whose break-down products are involved in stress response against herbivores, pathogens, and abiot

78 key transcription mediator of the integrated stress response, also activates AXL and suppresses senes

79 s) to determine whether they respond to cell stress response and affect signaling pathways.

80 th genetic mutations that affect both the ER stress response and autophagy.

81 Focusing on genes with roles in stress response and behavior, we assessed the effects of

82 The stress response and cell survival are necessary for norm

83 PD, and phobias is via the activation of the stress response and central and peripheral immune cells

84 se temporal regulation of the SigB-dependent stress response and differential regulation of translati

85 We show that Liraglutide modulates the ER stress response and elicits ER proteostasis and autophag

86 ht constitute an important signaling hub for stress response and for pathophysiology and treatment of

87 ncreased hypothalamic-pituitary-adrenal axis stress response and impaired sensorimotor gating, phenot

88 Stress granules are important in the stress response and may contribute to some degenerative

89 identified a set of target genes involved in stress response and neural plasticity.

90 in situ temperatures, possessing a suite of stress response and nutrient cycling genes to fix carbon

91 cies involved in iron utilization, oxidative stress response and oncogenic pathways.

92 but not spxA2, is required for the oxidative stress response and pathogenesis.

93 Protein can modulate the surgical stress response and postoperative catabolism.

94 aralogous gene otpa but not otpb affect both stress response and social preference.

95 ld be considered an elemental feature of the stress response and that circulating exosomes transporti

96 on of ERalpha expression mediated by the EnR stress response and the feed-forward regulation between

97 der stress could provide crucial insights on stress response and toxicity pathways.

98 tion have been shown to play a major role in stress responses and adaptation.

99 d to radiation, causing genomic instability, stress responses and altered apoptosis or cell prolifera

100 s identified enriched transcripts related to stress responses and apoptosis at the wound healing stag

101 g operates and coordinates resistance during stress responses and modulates plant development.

102 esults implicate CDK19 as a regulator of p53 stress responses and suggest a role for CDK19 in cellula

103 ber expansion for multiple genes involved in stress responses and the biosynthesis of secondary metab

104 OS signaling-mediated regulation of cellular stress responses and thermogenesis, and how O2 deficienc

105 le pathways to control metabolism, oxidative stress response, and cell cycle.

106 opin-releasing factor (CRF) orchestrates the stress response, and excessive CRF is thought to contrib

107 relevant to anxiety, depression, cognition, stress response, and social behavior.

108 protein deacylases regulating metabolism and stress responses, and are implicated in aging-related di

109 vital role in the regulation of metabolism, stress responses, and genome stability.

110 rates, nitric oxide production levels, shear stress responses, and TNFalpha-induced leukocyte adhesio

111 e enzymes, which is a key to the temperature stress response, appeared to be temperature ecotype-spec

112 The anatomic structures that mediate the stress response are found in both the central and autono

113 Given that neuroendocrine stress responses are conceptualized as biomarkers of str

114 SIGNIFICANCE STATEMENT: Dysfunctional stress responses are linked to a number of somatic and p

115 in signaling, hormone, cell wall, and biotic stress responses are over-represented in differentially

116 Although our knowledge of how stress responses are regulated is accumulating, a genome

117 hrough which PGRPs induce these bactericidal stress responses are unknown.

118 olds great promise as a biomarker of in vivo stress responses as it is highly induced in stressed or

119 e BONCAT method to researchers interested in stress responses as well as translational and posttransl

120 pocampus (DH) is prominently involved in the stress response, as are the locus coeruleus norepinephri

121 m stress is an evolutionarily conserved cell stress response associated with numerous diseases, inclu

122 Moreover, CPR-4 causes these effects and stress responses at unexposed sites distal to the irradi

123 Inhalational MtbDeltasigH, a stress-response-attenuated strain, protected against let

124 dant functions in the regulation of the salt stress response but opposite functions to control flower

125 ndant functions in the regulation of abiotic stress responses but have opposite functions to control

126 ncRNAs play important roles in plant abiotic stress responses but lincRNAs and TE-lincRNAs might act

127 Thus, PEPD stores p53 for the stress response, but this also renders cells dependent o

128 Sabotaging of the oxidative stress response by an oncogenic noncoding RNA.

129 FANCD2 also functions during the replication stress response by mediating the restart of temporarily

130 osphate (G3P) is important for environmental stress responses by eukaryotic microalgae.

131 ghlight lipid metabolism and a change in the stress response capacity of corals as key parts of this

132 rioles and of inflammatory, immunologic, and stress-response cascades in PD arterioles.

133 , here we identify strata of MEcPP-sensitive stress-response cascades, among which we focus on select

134 nt development by light (PIF3, HY5) and cold stress response (CBF).

135 rs that have a pivotal role in the oxidative stress response, cellular homeostasis, and organismal li

136 teady laminar flow induced the classic shear stress responses commonly in blood vascular endothelial

137 Thus two distinct proteotoxic stress responses control phospholipid metabolism.

138 al transfer of stress level triggers similar stress responses (corticosterone secretion) in brood bys

139 er fresh weights of E. cyaneus) and cellular stress response (CSR) capacity, potentially causing spec

140 tases control biological processes including stress responses, development, and cell division in all

141 d XLID-specific down-regulation of oxidative stress response DNA polymerase (Pol) lambda caused by hy

142 We have further found that EnR stress response down-regulates ERalpha expression throug

143 1 results in its decreased binding to the ER stress response element present in the promoter region o

144 of SNF1 mutation proteins 2 and 4) bind the stress-response element in gene promoters in the yeast S

145 ssible mechanism by which starvation-induced stress response factors may prime quiescent cells to ree

146 their analogs have emerged as wide-spectrum, stress response factors protective in amyloid disease mo

147 e data also suggest that other mitochondrial stress response factors within the MDP family may be ame

148 Here, we show that general stress response factors, Msn2 and Msn4, function as mast

149 novo rhythmicity during aging, enriched for stress-response functions.

150 (GBF3) were identified as candidate drought stress response genes and the role of GBF3 in drought to

151 y of MR to regulate lipogenic and integrated stress response genes in liver was not compromised in Fg

152 protein folding, induced numerous oxidative stress response genes not previously known to be ATF6-in

153 Cs maintain chromosomal accessibility at key stress response genes that are activated by the primary

154 t, permafrost soils have a lower richness of stress response genes, and instead the metagenome is enr

155 nscription factor 6 alpha), which induces ER stress response genes.

156 activating carbohydrate metabolism genes and stress response genes.

157 iR-500a-5p there was enrichment in oxidative stress response genes.

158 ironmental isolates in virulence factors and stress response genes.

159 transport and the up-regulation of oxidative stress response genes.

160 transcription factor 4 (ATF4) mRNA to induce stress response genes.

161 actor eIF2alpha, enabling the translation of stress response genes; among these is GADD34, the protei

162 iquid resulted in the induction of oxidative stress-response genes including GCLM, GCLC, GPX2, NQO1 a

163 ed various strategies, including the general stress response (GSR).

164 gulatory elements control spatially specific stress response has yet to emerge.

165 These stress responses have generally been dissected in vitro

166 Furthermore, these results suggest that stress responses have the potential to differentially im

167 between growth and ER stress defense by the stress response hormone salicylic acid (SA) and the UPR,

168 anch of the integrated endoplasmic reticulum stress response (IERSR) is activated by Leishmania and t

169 We describe aspects of phero-perception, stress responses, immune function and regulation of gene

170 bosomal protein genes from the environmental stress response in a manner partly correlated with the c

171 ster transcriptional regulators of phosphate stress response in Arabidopsis thaliana also directly re

172 The recent finding of a U-specific stress response in Caulobacter crescentus has provided a

173 suggests an important role for the oxidative stress response in lung tumorigenesis.

174 g stress create a "contagious" physiological stress response in the observer?

175 serine residue to prevent activation of the stress response in unstressed plants.

176 hysiological links between PML and oxidative stress response in vivo remain unexplored.

177 inar flow commonly induces the classic shear stress responses in blood endothelial cells and lymphati

178 sible roles in mediating hormone and abiotic stress responses in cassava.

179 Here, we compared Cu stress responses in cultures and natural populations of

180 n by the MAPK Sty1 is required for oxidative stress responses in fission yeast cells by promoting tra

181 es has greatly advanced our understanding of stress responses in humans and their underlying neurobio

182 n the brain's reward circuitry in modulating stress responses in mice.

183 al survival and is crucial for virulence and stress responses in microbial pathogens.

184 High social status reduces stress responses in numerous species, but the stress-buf

185 Proteomic plasticity undergirds stress responses in plants, and understanding such respo

186 is essential for developmental processes and stress responses in plants.

187 mycin complex 1 function, and hyperammonemic stress response including autophagy markers normally fou

188 vely growing bacteria, and eliciting similar stress responses, including the heat shock response.

189 racellular ATP is a signal involved in plant stress responses, including wounding, perhaps to evoke p

190 ntrol is to help the cell mount an effective stress response, independent of the role of editing in m

191 ranscription rate during the early stages of stress response, indicating orthogonal transcriptional c

192 ops that are involved in potentially chaotic stress response, indicating that the dynamics of these p

193 e tested how individual differences in acute stress responses influence valence bias and how this dec

194 rk is a highly conserved network of cellular stress responses involved in maintaining the homeostasis

195 The integrated stress response is able to rapidly shut down the synthes

196 An important component of the stress response is activation of the locus coeruleus (LC

197 to other defense systems, the NRF2-mediated stress response is compromised in aging and neurodegener

198 Here, we show that the role of DISC1 in stress responses is evolutionarily conserved and that DI

199 are both selectively enhanced by integrated stress response (ISR) activation.

200 nvolved in the regulation of the integrative stress response (ISR) and pro-inflammatory pathways.

201 The integrated stress response (ISR) is activated by hypoxia and protec

202 agent asparaginase activates the integrated stress response (ISR) kinase GCN2 and inhibits signaling

203 eIF2alpha-P and the accompanying integrated stress response (ISR) selectively enhance translation of

204 Asparaginase activates the integrated stress response (ISR) via sensing amino acid depletion b

205 The integrated stress response (ISR), a conserved eukaryotic response t

206 abolism through activation of the integrated stress response (ISR).

207 itor of eIF2B, which triggers the integrated stress response (ISR).

208 r inappropriate activation of the integrated stress response may contribute to pathogenesis in a subs

209 uced latency and that interference with this stress response may resolve the clinical problem of recr

210 e as an inflammation regulator or a cellular stress response mechanism under chronic alcohol conditio

211 ting the activation of a specific organellar stress-response mechanism, the mitochondrial unfolded pr

212 hesis, resulting in an endoplasmic reticulum stress response mediated by Perk.

213 e several with putative functions related to stress responses mediated through the PI3K/TOR or MAPK s

214 all, we identify miR-500a-5p as an oxidative stress response miRNA whose activity may define breast c

215 To address this, we focused on a stress response network where the multiple antibiotic re

216 Stress response networks frequently have a single upstre

217 However, very little is known about how stress response, neural processing of reward, and depres

218 nzymes signaling energy stress and oxidative stress response, nicotinamide adenine dinucleotide (NAD(

219 we investigated the mechanism of Cd induced stress response of L. plantarum strains using the isobar

220 data allowed discrimination between general stress response of maize and that unique to severe cold.

221 en topoisomerase I and RNA polymerase during stress response of mycobacteria.

222 ning dynamics are dictated by the mechanical stress response of the cell wall matrix, and as the turg

223 we propose a model for the DnrF-mediated NO stress response of this marine bacterium.

224 molecular mechanisms involved in the drought stress responses of sugarcane impairs the development of

225 cancer cells without affecting the oxidative stress response or the oncogenic pathways included in th

226 and regulator of cytoskeleton, cell growth, stress response, or immune cell function; however, the m

227 teroids, given their well-documented role in stress-response orchestration.

228 devices, the proteomic dynamics of the yeast stress response pathway were carefully studied based on

229 gen species and activation of the Jun kinase stress response pathway.

230 These data illustrate an mRNA translation stress-response pathway for E2F1 activation that is expl

231 bserved, suggesting a possible effect on the stress-response pathway.

232 ions that are associated with this essential stress-response pathway.

233 -alpha-MKK4 arm of the endoplasmic-reticulum-stress-response pathway.

234 ammalian cells activate a complex network of stress response pathways collectively termed DNA damage

235 Implicated in persistence and stress response pathways in bacteria, RelE shuts down pr

236 ities in downstream signaling pathways or in stress response pathways that are permissive for strong

237 ging is associated with a broad induction of stress response pathways, although the specific genes an

238 , but its regulation in the context of other stress response pathways, such as those mediated by heat

239 Common stress genes were enriched with known stress response pathways, while combination unique-genes

240 n and directly link reactivation to neuronal stress response pathways.

241 unctions as a negative regulator of cellular stress-response pathways by mediating a feedback loop of

242 proteins involved in multiple regulatory and stress-response pathways in cells.

243 und healing-, cytoskeleton-, immune system-, stress response-, phosphorylation- and protein modificat

244 A gene ontology analysis reveals that stress response processes are significantly overrepresen

245 stresses and must fine-tune their growth and stress-response programs to best suit their environment.

246 The DNA replication stress response protein SMARCAL1 stabilizes DNA replicat

247 Our data suggest that the levels of stress-response proteins Pdr5p and Trx2p in the mother c

248 in the heart and that sirtuins are commonly stress-response proteins, we used an established model o

249 ) all these changes together induce multiple stress responses, reduced biosynthesis, cell viability a

250 stabilizes a complex between 14-3-3 and the stress response regulator GCN1, inducing GCN1 turnover a

251 it bacterial growth, trigger upregulation of stress-response regulons, induce substantial disruption

252 t the mechanisms through which DISC1 affects stress responses remain poorly understood.

253 been deemed to be a promising candidate for stress response research because of its high capacity to

254 Celastrol is known to elicit a cellular stress response resembling the response to heat shock, b

255 ysis suggested an involvement of lincRNAs in stress response, signal transduction, and developmental

256 ls activates caspase cascade and endoplasmic stress response signaling.

257 ional analysis of which showed enrichment of stress response, signaling pathway and extracellular pro

258 By identifying the stress response strategies activated by Nrf2, we also hi

259 to cellular evaluations of the environmental stress response, studying a range of well-rationalized m

260 ons, cells have evolved compartment-specific stress responses, such as the unfolded protein response

261 athways (chromatin organization and cellular stress response) suggesting that the process of lung car

262 , the salamander cells did not exhibit major stress responses, suggesting that the host cell experien

263 transcription and p53-independent nucleolar stress response supports a central role for this nuclear

264 re, we report that the fungal nitrooxidative stress response suppresses host defences to facilitate t

265 ELS), which produces excessive activation of stress response systems broadly throughout the child's b

266 cade of coordinated physiological changes in stress response systems.

267 oapoptotic arms of the endoplasmic reticulum stress response that is probably secondary to inappropri

268 e angiogenin is a component of the mammalian stress response that is secreted by renal epithelial cel

269 hondrial dysfunction activates an integrated stress response that locally induces muscle atrophy, but

270 e approaches to stimulate cellular intrinsic stress responses that are capable of inhibiting CMV infe

271 4me3 binding at genes critical to behavioral stress response, the most robust being the oxytocin rece

272 the master regulator of a second proteotoxic stress response, the unfolded protein response (UPR).

273 natively expressed, GR likely contributes to stress responses through non-transcriptional mechanisms

274 We conclude that an interdependent oxidative stress response to hyperglycemia perturbs neutrophil cyt

275 IF2alpha kinases function in the integrative stress response to inhibit general protein synthesis coi

276 mature cytoplasmic tRNAs are cleaved during stress response to produce tRNA fragments that function

277 ve oxygen species (ROS) activate an adaptive stress response to promote longevity.

278 However, the contribution of the replication stress response to the development of malignancies remai

279 Accordingly, cells have developed stress responses to deal with misfolded proteins.

280 Cellular stress responses to energy insufficiency can impact viru

281 , and we explore the concept of targeting ER stress responses to enhance the efficacy of standard che

282 ormone mediating developmental processes and stress responses to stimuli such as infection.

283 cals, such as ethanol, activates the primary stress response transcription factor heat shock factor 1

284 lification of the amino acid response and ER stress response transcriptional signatures.

285 nd expression of genes involved in oxidative stress responses, tumor progression and chemoresistance.

286 specific genomic mutations and alteration of stress responses, ultimately restoring normal ATP produc

287 he UPS may function to suppress FDH mediated stress responses under favorable growth conditions.

288 that V. fischeri may help modulate the host stress responses under modeled microgravity.

289 transcription factor activation but mount a stress response upon coordinated regulation, even in a s

290 determine the role of gamma2-AMPK in cardiac stress response using bioengineered cell lines and mouse

291 )-expressing neurons regulates the mammalian stress response via the hypothalamic-pituitary-adrenal (

292 sinosteroids (BRs) regulate plant growth and stress responses via the BES1/BZR1 family of transcripti

293 med that the induction of this mitochondrial stress response was essential for the maintenance of mit

294 l kinase activity upon mitochondrial damage, stress-response was largely unaffected over time, as exp

295 ose involved in the metabolism of sugars and stress response were highlighted.

296 t to mediate cardiac mechanotransduction and stress responses, whereas the mitochondrial ATP synthase

297 7-41 degrees C) resulted in a classical heat-stress response with up-regulation of cellular chaperone

298 The mechanisms that integrate stress responses with growth are poorly understood.

299 C2 signaling pathways to coordinate cellular stress responses with sterol homeostasis.

300 ompletely bypassed by activating an envelope stress response without compromising trafficking of esse