ライフサイエンスコーパス: stress to

1 untreated mice, diminished retinal oxidative stress to 70% of the untreated level, and markedly ameli

2 When applying mechanical stress to a bulk metallic glass it responds with elastic

3 ved in cross-linked networks by distributing stress to a small fraction of highly strained connected

4 ished in the past year have linked oxidative stress to a variety of upper gastrointestinal insults.

5 parameters when the mitochondrial network is stressed to a critical state.

6 o significantly blunted the ability of acute stress to activate c-Fos expression within the anterior

7 rats, reduces or blocks the ability of acute stress to activate hindbrain neurons that are immunoreac

8 es are essential structures for transmitting stresses to activate cytoplasmic proteins.

9 t couple detection of pathogens and cellular stress to activation of Caspase-1, and consequent IL-1be

10 y that translates laminar flow-induced shear stress to activation of lymphatic sprouting.

11 tivation, thus linking endoplasmic reticulum stress to activation of the NLRP3 inflammasome.

12 nked quantitative and qualitative aspects of stress to adolescent and adult outcomes, a number of que

13 treatments with exogenous ABA or dehydration stress to advance our understanding of the features requ

14 ly used by the host cell to combat genotoxic stress, to aid its own replication.

15 l that cells detect and respond to oxidative stress to allow adaptation and repair damage, the underl

16 es formed, thereby providing sufficient back stress to allow ice shelf thickening.

17 en appears to act in synergy with epithelial stress to allow intraepithelial cytotoxic T cells to kil

18 n factor that undergoes self-cleavage during stress to allow the expression of DNA repair functions a

19 trolled in response to a variety of cellular stresses to allow the rapid reprogramming of cellular ge

20 of B-Raf reduces T cell resistance to shear stress to alpha4beta1 integrin ligands vascular cell adh

21 sothermal titration calorimetry with osmotic stress to also measure hydration changes accompanying li

22 udy that focused on the ability of oxidative stress to alter cysteinyl leukotriene generation.

23 nt protein deacetylase, senses environmental stress to alter intestinal integrity.

24 respectively, are regulated during oxidative stress to alter O-GlcNAcylation are not fully characteri

25 e sex difference in the ability of restraint stress to alter REMS.

26 androgens influence the ability of restraint stress to alter sleep states.

27 nown about how sex influences the ability of stress to alter sleep.

28 Mechanical stress to alveolar walls may cause progressive damage af

29 The biological underpinnings linking stress to Alzheimer's disease (AD) risk are poorly under

30 These in vitro findings linking oxidative stress to amyloid fibril formation may be significant to

31 This pathway spans from initial stress to antibiotic target and demonstrates that TA beh

32 cleavage of SIRT1, a mechanism linking cell stress to apoptosis and SIPS.

33 many diseases, but the mechanisms linking ER stress to apoptosis are incompletely understood.

34 a stress that can act additively with other stresses to arrest cells in G1 in a p38-dependent fashio

35 of the mouse spermatozoon against oxidative stress to assure fertilizing competence.

36 at such unfavorable topography may present a stress to attached cells.

37 core with ceftriaxone the capacity of acute stress to augment the acquisition of cocaine self-admini

38 By applying environmental stress to bacteria in a microfluidic platform, we can co

39 These results reveal hyperosmotic stress to be a potent activator of caspase-3 in hippocam

40 ication of lipid peroxide-mediated oxidative stress to be different in survivors and non-survivors.

41 ecent clinical studies demonstrate oxidative stress to be present early in ADPKD.

42 mechanisms of drug action and resistance was stressed to be essential for the design of new agents an

43 n a silica cladding allows large anisotropic stresses to be set into the crystalline material so that

44 cks, as well as the causes of these physical stresses, to be identified.

45 oss the range of dehydration from mild water stress to beyond turgor loss point.

46 The latter reflects possible oxidative stress to biological macromolecules, yielding supporting

47 of a kappa antagonist administered following stress to block forced swim stress-induced reinstatement

48 is a source of potential psychophysiological stress to both children and their caregivers.

49 en both milk samples were subjected to shear stress to break the curd system at constant shear rate,

50 Paclitaxel-induced ER stress to breast cancer (BCa) cells promotes RNF5 associ

51 Stress to calcium metabolism was defined as elevated int

52 activation of JNK or IKK, is pivotal for ER stress to cause hepatic insulin resistance.

53 as miR-451 depletion synergizes with oxidant stress to cause profound anemia in zebrafish embryos.

54 Using a novel apparatus to apply mechanical stress to cell-cell junctions, we showed that knockdown

55 ture measurements have the advantage of less stress to cells.

56 ve suggested one potential mechanism linking stress to cellular aging, disease and mortality in human

57 Brain circuits are plastic and remodeled by stress to change the balance between anxiety, mood contr

58 Application of high fluid shear stress to chondrocytes recapitulates the earmarks of OA,

59 (a DegS homologue) is activated by cell wall stress to cleave MucA and release sigma(22).

60 f PTSD and suggests the potential of ongoing stress to compound initial stress reactions and lead to

61 cells actively exert physical forces (solid stress) to compress tumour blood vessels, thus reducing

62 his report we have examined the use of shear stress to condition synthesized material prior to applic

63 groups were exposed to chronic unpredictable stress to confirm findings from the FST.

64 e renin angiotensin system and macrophage ER stress to contribute to the development of hypertension

65 that functions under conditions of metabolic stress to control systemic energy homeostasis and the ov

66 ther high or low stress, caused the cellular stress to converge to a common level.

67 ncentrations of aldosterone increase oxidant stress to convert GC to an NO(.)-insensitive state, resu

68 RAD52 colocalizes with OGG1 after oxidative stress to cultured cells, but not after the direct induc

69 KD1-dependent mechanism that links oxidative stress to decreased CREB protein abundance is predicted

70 s of anxiety-like behavior, and to restraint stress to determine stress responsiveness.

71 ced swim stress that adds to the interaction stress to determine the global contractility or extensib

72 strains with differential responsiveness to stress to determine whether CRH might also differentiall

73 ged the amygdala, a brain region involved in stress, to determine whether its resting metabolic activ

74 d formula and subjected to asphyxia and cold stress to develop NEC.

75 was activated by extracellular hyperosmotic stress to directly phosphorylate c-Jun in the serine 63

76 ortex is moderately diminished during normal stress to disinhibit these loci.

77 e data support the hypothesis that oxidative stress to DNA is induced in liver by ethanol.

78 Oxidative stress to E. coli occurred via formation of hydroxyl rad

79 -126 and by the application of laminar shear stress to ECs.

80 ver, the potential for oxidative/nitrosative stress to elicit an autoimmune response or to contribute

81 ibly manipulated between 0-8 GPa compressive stresses to enable systematic and reversible changes in

82 xert harmful effects, ranging from oxidative stress to endothelial dysfunction, nitric oxide disarray

83 is a strategy employed by plants exposed to stress to enhance resistance against future stress episo

84 utrients and growth factors and inhibited by stress to ensure that cells grow only during favorable c

85 ost-transcriptional regulation under uranium stress to enter a cellular dormant state, thereby provid

86 protein response and thus directly links ER stress to ER-phagy.

87 tumour cells use FoxM1 to control oxidative stress to escape premature senescence and apoptosis.

88 al epithelia require a higher level of shear stress to evoke a cytosolic calcium increase than do mou

89 the DA system may underlie the propensity of stress to exacerbate psychotic disorders or predispose a

90 revisiae cells treated with and without salt stress to explore population variation and identify cell

91 We used zebrafish with FLD and hepatic ER stress to explore the relationship between Atf6 and stea

92 the symmetry between tensile and compressive stresses to facilitate mesoscale network contraction of

93 were prepared, thermomechanically cycled and stressed to failure under tension.

94 fic regions of the VTA both during and after stress to fuel later escalated cocaine taking and seekin

95 The mechanisms linking ER stress to HACS activation are not known.

96 t the gamble to induce systemic self-harming stress to harm pathogens may not pay off in the end.

97 ses are set into motion that link early life stress to health disorders in the later years?

98 Research relating stress to health has progressed from anecdotal evidence

99 le reviews recent studies connecting chronic stress to health outcomes in parents of children with in

100 had similar aortic dimensions and wall shear stress to healthy volunteers and younger patients with B

101 that silencing Nup88 in IMCD3 cells acutely stressed to hypertonic conditions reduces nuclear retent

102 n Ganges and Prayon plants in response to Cd stress to identify transporter genes that were more high

103 er the NLRP3 inflammasome connects metabolic stress to IL-1beta-mediated inflammation and provides a

104 Application of fluid shear stress to immortalized osteoblasts from Pkd1(null/null)

105 ts define a pathway linking vascular oxidant stress to immune activation and aortic stiffening and pr

106 PFC is critically involved in females during stress to impair subsequent learning and does so via com

107 uture decades, we can expect deficit-related stress to increase and consequently Douglas fir growth t

108 s to acute stress, and blunts the ability of stress to increase anterior pituitary release of adrenoc

109 r 1 (HSF1) mediates the cellular response to stress to increase the production of heat shock protein

110 rated rats were subjected to water avoidance stress (to induce visceral hypersensitivity), then given

111 st-menopausal women underwent a passive heat stress to induce hot flushes at baseline and follow-up.

112 es suggest that FAAH is required for chronic stress to induce hyperactivity and structural remodeling

113 FC derived from tumour cells is required for stress to induce lymphatic remodelling and that this dep

114 ground, Rps27l disruption triggers ribosomal stress to induce p53 and apoptosis, whereas under Trp53(

115 iption factor that binds HSP promoters after stress to induce their transcription, interacts with the

116 which is activated upon heat shock and other stresses to induce the expression of molecular chaperone

117 ertilization interacted with competition and stress to influence biomass and changes in height, respe

118 nonsynonymous OXTR SNP interacted with early stress to influence relevant behavioral stress reactivit

119 Critically, rs12938031 interacted with stress to influence reward learning: both behaviorally a

120 rnight fast by blocking the ability of acute stress to inhibit food intake, and by attenuating stress

121 of biological systems ranging from cellular stress to insulin signaling.

122 ctivation, to clarify the relationship of ER stress to intra-acinar trypsinogen activation in pancrea

123 cystin-2 in transmitting extracellular shear stress to intracellular NO biosynthesis.

124 degrees C following 60 min 42 degrees C heat stress to investigate specifically the early events in t

125 ngle neutron scattering coupled with osmotic stress to investigate the hydration of two proteins, lys

126 tant exhibiting constitutive plastid osmotic stress to investigate the molecular and genetic pathways

127 (Populus x canescens) were exposed to water stress to investigate xylem sap sulfate and ABA, stomata

128 etabolic derangement and excessive oxidative stress to ion channel/transporter dysfunction that predi

129 However, the coupling of ER stress to IRE1 oligomerization and activation has remain

130 ex vivo perfusion of arterial laminar shear stress to isolated veins further confirmed the correlati

131 involvement in adaptive threat-biases under stress, to its chronic engagement in anxiety disorders i

132 ory activation of autophagy during prolonged stress to keep the levels of this process under a safe a

133 ytes increased their resistance to oxidative stress to levels that were comparable with stimulated yo

134 suggest a novel mechanism linking oxidative stress to ligand-independent cleavage of p75(NTR), resul

135 but the molecular mechanisms that link this stress to lignification remain largely unknown.

136 e heart under conditions of in vivo cellular stress to likely modulate vascular responses to neurohor

137 is a technique for applying local mechanical stresses to living cells.

138 escence microscopy, we applied defined shear stress to low- or high-affinity LFA-1 and imaged the spa

139 ts performed better than the wild type under stress to maintain a favorable instantaneous water use e

140 litating DNA replication under conditions of stress to maintain genomic integrity.

141 nd survival in vivo by resolving replicative stress to maintain genomic stability.

142 s the distribution and magnitude of traction stresses to maintain a constant strain energy.

143 ases degrading collagen are activated during stress to make proline available, and proline oxidase, t

144 eptibility of mutants sensitive to oxidative stress to MalE-LacZ lethality indicates that ROS contrib

145 To test this, we used abiotic stresses to manipulate the availability of reducing powe

146 her temperatures, bringing increased drought stress to many ecosystems.

147 with the radiotracer injections at rest and stress to measure blood flow.

148 endotoxin (LPS) model of evoked inflammatory stress to measure plasma IL-1 receptor antagonist (IL1RA

149 G was computed as the ratio of imposed shear stress to measured shear strain.

150 Whether Nox4 acts as a sensor of energy stress to mediate activation of autophagy is unknown.

151 xR is a redox regulator that senses peroxide stress to mediate antibiotic resistance in P. aeruginosa

152 ay in response to DNA damage and replication stress to mediate cell cycle arrest.

153 acid (ABA) is induced in response to abiotic stress to mediate plant acclimation to environmental cha

154 the monolayer edge better align velocity and stress to migrate faster toward the open space.

155 The mechanism that couples shear stress to migration has not been fully elucidated.

156 al stability of nanobeams under high tensile stress to minimize thermal buckling effects, therefore k

157 sessile organisms can adapt to environmental stress to mitigate its adverse effects.

158 It is proposed that stress to mitochondria of individual RGCs is a major tri

159 ngs suggest that CaMKII could couple disease stress to mitochondrial injury.

160 ession networks before and after exposure to stress to model the effect of stress on mutational robus

161 Ball-milling utilizes mechanical stress to modify properties of carbon nanotubes (CNTs) i

162 Similarly, the ability of acute stress to modulate amygdala FAAH and AEA in both rats an

163 N is the critical link that allows oxidative stress to modulate nSMase2 phosphorylation and function.

164 in reproductive tissues in response to heat stress to modulate resource allocation dynamics.

165 inuously reorganize, adapting in response to stress to modulate the calcium signaling apparatus.

166 An analytic model for the strength, or stress to move a dislocation, owing to the random field

167 l the channel banks create just enough shear stress to move the median-sized gravel particles on the

168 importance of cell contractility and tissue stress to multicellular vertex formation and resolution,

169 the ratio of horizontal compressive tectonic stresses to near-surface gravitational stresses is relat

170 ess (>300 kPa) in the cap can intensify this stress to nearly 600 kPa when the cap thickness is <65 m

171 dent of frequency offset, and (d) reduce the stress to NMR hardware (e.g., cryoprobes).

172 f control on behavior, led even controllable stress to now produce functional desensitization of DRN

173 s and cytoplasm serves to couple cytoplasmic stress to nuclear cyclin/CDK inhibition.

174 s suggested defense reactions towards biotic stress to occur which did not lead to adequate responses

175 is definition to include the transmission of stress to offspring via early postnatal care, as animal

176 strategy based on tolerating the effects of stress to one of escaping the stress via reproduction.

177 in its toxicity profile from mainly membrane stress to one that exhibited not only sustained membrane

178 ing to multiple insults, including oxidative stress to orchestrate apoptotic and autophagic cell deat

179 at activate innate immunity, thus connecting stress to organ-specific inflammation.

180 ggests a physiological benefit of mechanical stress to outflow cells in organ culture.

181 riments use thermal, chemical, or mechanical stress to perturb the folding equilibrium for examining

182 Intriguingly, while application of oxidative stress to phase I and II iron-limited cells similarly ox

183 oles in the signaling steps that link biotic stresses to plant defense responses and growth changes.

184 r rapidly fluctuating light conditions cause stress to plants.

185 uopathies, but the consequences of genotoxic stress to postmitotic neurons are poorly understood.

186 hurricane symptomatology and interacted with stress to predict externalizing symptoms.

187 ly exacerbating and buffering the effects of stress, to predict anthropometry during childhood, and b

188 Research links psychosocial stress to premature telomere shortening and accelerated

189 ulates vascular function by limiting oxidant stress to preserve bioavailable nitric oxide (NO(*)).

190 chondria must buffer the risk of proteotoxic stress to preserve bioenergetics, but the role of these

191 endothelial cells during elevated oxidative stress to preserve functional viability of the intima.

192 d in response to DNA lesions and replication stress to preserve genome integrity.

193 buffer external (environmental) or internal stresses to preserve the biological integrity of the org

194 al for targeting IL-33, ILC2s, and oxidative stress to prevent and/or treat asthma development relate

195 evolved to cope with endogenous or exogenous stress to prevent chromosomal instability and maintain c

196 kinase Rad53 is activated during replication stress to prevent fork collapse, an essential but poorly

197 quickly adjusted in response to replication stress to prevent genome instability.

198 egrity by clearance of individual HSCs after stress to prevent propagation of damaged stem cells.

199 uitinases associate more with Rsp5 upon heat-stress to prevent the assembly of K63-linked ubiquitin o

200 llular checkpoints that respond to damage or stress to prevent tumorigenesis, the transcriptional con

201 e, seasonal and annual streamflow, and water stress) to projections of future climate.

202 transmits structural changes in response to stress to promote holdase activity is unknown.

203 a/delta can repress this oncogene-induced ER stress to promote senescence in accordance with its role

204 the translational landscape during cellular stress to promote survival.

205 at shock proteins, during times of oxidative stress to protect against proteotoxicity.

206 op effective strategies to inhibit oxidative stress to protect aging vasculature.

207 , we propose that autophagy limits metabolic stress to protect the genome, and that defective autopha

208 is induced during inflammation and oxidative stress to protect tissues from oxidative damage.

209 nd respond dynamically to pH and temperature stresses to protect client proteins from aggregation.

210 2/RelB and IKK2-p65, is activated by various stresses to protect or damage the liver, in context-spec

211 re was no indication of diminished oxidative stress to proteins or lipids, and no evidence for anti-i

212 ences may exist in the relation of oxidative stress to pulmonary function.

213 s then underwent a period of whole-body heat stress to raise oral temperature 0.8-1.0 degrees C above

214 present study, we determined if hyperosmotic stress to rat hippocampal slices activates p38 and JNK a

215 on the GR, monitoring the level of cellular stress to redirect glucocorticoid-regulated signaling th

216 hemical marker of depression, the ability of stress to reduce BDNF in the hippocampus.

217 at Dps acts as a checkpoint during oxidative stress to reduce initiations, providing an opportunity f

218 Here, we show that cells can sense nitrogen stress to reduce target of rapamycin complex-1 (TORC1) a

219 aR is phosphorylated in response to membrane stress to regulate downstream target operons.

220 switch, which is activated during oxidative stress to regulate the balance between cell survival by

221 ient status, growth factor availability, and stress, to regulate cellular and organismal growth.

222 e and expression interact with environmental stress to reinstate alcohol-seeking behavior.

223 -cleaved SERPINB11 was unable to undergo the stressed-to-relaxed transition typical of inhibitory typ

224 regulated proteolysis of cTnI during cardiac stress to remove the unique cardiac N-terminal extension

225 undant molecular responses to neutralize the stress, to repair the damage and to eventually grow insi

226 and can be activated in response to diverse stresses to replenish all blood cell types.

227 obtained from our previous rest study by the stress-to-rest TIAC ratio obtained from the rest-stress

228 latory pathway in Manduca sexta enables heat stress to reveal a hidden reaction norm of larval colora

229 a means of reducing the effect of oxidative stress to RPE cells in age-related macular degeneration.

230 ant, suggesting that CYP20-3 links light and stress to SAT1 activity and cysteine biosynthesis.

231 ted within blood vessels by high-fluid shear stresses to selectively target drugs to sites of vascula

232 ansiently increases in response to oxidative stress to sequester and oxidize Fe2+, which would otherw

233 fine a novel metabolic pathway that links ER stress to skeletal muscle integrity and function.

234 ne inactivation of Rps27l triggers ribosomal stress to stabilize Mdm2, which degrades Mdm4 to reduce

235 ndividuals with a history of repeated social stress to substance abuse behaviors.

236 advances have allowed the study of oxidative stress to tackle fundamental questions and have provided

237 s the first study (to our knowledge) to link stress to telomere length in a non-WEIRD population, our

238 for a mechanism linking cumulative childhood stress to telomere maintenance, observed already at a yo

239 ecological momentary assessment of patients' stress to test hypotheses about clonidine's behavioral m

240 We examined the effects of a modest heat stress to test the hypothesis that SSNA responses could

241 cation of an external vibrational mechanical stress to that tissue.

242 echanism to eliminate cells during metabolic stress to the advantage of a multicellular organism.

243 In the case of local salt stress to the Arabidopsis thaliana root, Ca(2+) wave pro

244 However, they can also mislocalize and cause stress to the bacterial cell, which is dealt with by the

245 Methods to decrease biomechanical stress to the bone-implant interface appear appropriate

246 biomechanical approach was used to decrease stress to the bone-implant interface.

247 Initial damage or stress to the coral via other competitive mechanisms is

248 meability can be modulated by applying shear stress to the droplet interfaces, inducing flow parallel

249 tivity of bortezomib by promoting additional stress to the endoplasmic reticulum of MM cells.

250 both a clinical problem and a psychological stress to the families involved.

251 This minimizes stress to the FEC cultures and permits a finely balanced

252 Hypoxia is a common stress to the fetus and results in decreased protein kin

253 host inflammatory response confer oxidative stress to the gastric epithelium during H. pylori infect

254 triggers represents a qualitatively distinct stress to the host immune system, yet our understanding

255 des insight into a new paradigm linking cell stress to the immune response, and serves as a template

256 ities in IECs, thus linking cell-specific ER stress to the induction of organ-specific inflammation.

257 caspase-2-dependent mechanism that relays ER stress to the mitochondria to promote inflammation, inte

258 redox regulatory switch that links oxidative stress to the modulation of TDP-43 and its downstream ta

259 sive folding" design to apply conformational stress to the monomeric state.

260 ted States recover from acid deposition, the stress to the most susceptible populations of native col

261 eration of contractility following oxidative stress to the myocardium, particularly through a decreas

262 y TRPM2 as a key factor that links oxidative stress to the NLRP3 inflammasome activation.

263 e not only for contribution of mitochondrial stress to the pathology of ITP, but also clinical potent

264 Functional radiography provides the maximum stress to the pelvic floor, resulting in levator ani rel

265 A biomechanical approach to decrease stress to the posterior implants included splinting impl

266 that link pathogen recognition and cellular stress to the processing of the proinflammatory cytokine

267 sensing of microbial products and metabolic stress to the proteolytic activation of the proinflammat

268 owth, and a molecular mechanism linking this stress to the regulation of growth in developing organs,

269 MI/R-induced cardiac oxidative and nitrative stress to the same degree as that seen in WT mice.

270 sHSPs) are preferentially translocated under stress to the sarcomeres.

271 represented conflict situations or delivered stress to the subjects.

272 madelta T cells are activated in response to stress to the surrounding tissue and perform a number of

273 cell-free virus did not reflect the level of stress to the VZV-infected cell that was seen after inoc

274 that is proportional (at constant interface stress) to the -1/3 power of this rate.

275 resulting in a delay in the transmission of stresses to the intracranial cavity and lower intracrani

276 et exert minimal mechanical and inflammatory stresses to the vessel wall.

277 long with caspase-8 activation and oxidative stress, to their synergistic cytotoxic effects in leukem

278 fficient, defined as the ratio of protrusive stress to tissue-substrate friction, that allows classif

279 ction was observed in the transmission of ER stress to TLR4 KO macrophages, consistent with the fact

280 1P1 responds to S1P as well as laminar shear stress to transduce flow-mediated signaling in endotheli

281 logies to use nanoparticle-induced oxidative stress to treat disease in a site-specific fashion.

282 atin-remodelling factor that is activated by stress to trigger aberrant gene expression and cardiac m

283 anched actin networks builds up a sufficient stress to trigger sustained motility.

284 se motors generate sufficient thick-filament stress to trigger the transition to its long-periodicity

285 ability of cortisol, released in response to stress, to trigger a cascade of adaptive genomic and non

286 r the past 2 decades, the contribution of ER stress to various forms of liver diseases has been exami

287 minal kinases (JNKs) links exposure to acute stress to various physiological responses.

288 ins in the endoplasmic reticulum (ER) causes stress to which an unfolded protein response is activate

289 adiation (IR) is a physiologically important stress to which cells respond by the activation of multi

290 Available data suggest that the cold stress to which laboratory mice are ubiquitously subject

291 PA0943 may cause increased secretin-induced stress to which P. aeruginosa cannot respond.

292 Furthermore, the optimal shear stress to which the cells respond best does not alter th

293 riving force derives from the high degree of stress to which the DNA is subjected in the viral capsid

294 important source of environmental oxidative stress to which the skin is exposed, especially during s

295 epending on the function of the cells or the stress to which they are exposed.

296 epending on the function of the cells or the stress to which they are exposed.

297 acental angiogenesis depends on the type of 'stress' to which the pregnancy is subjected, and also di

298 l pathway, but rather one guided by uniaxial stress, to which the nanothreads consistently align.

299 of the airways modulate both the mechanical stresses to which the airways are exposed as well as the

300 inhibition of Hsp90 activity and temperature stress to wild-type cells.