1 e for [Ca(2+)] in regulating power output of
stretch-activated A-IFM.
2 Moreover, we found that longitudinal
stretch activated Akt, which up-regulated Ankrd2 express
3 In support of this idea,
stretch-activated and stretch-inactivated channels were
4 There were differences in the
stretch-activated and swelling-activated cation channel
5 modulates mechanosensitive (ie, swelling- or
stretch-activated)
anion channels was tested.
6 omoter only by NF-kappaB, whereas transverse
stretch activated Ankrd2 promoter by AP-1.
7 Interestingly, longitudinal
stretch activated Ankrd2 promoter only by NF-kappaB, whe
8 ition of AT(1) blocker to cultures inhibited
stretch-activated apoptosis in both myocyte populations
9 Such Hechtian transduction opens
stretch-activated Ca(2+) channels and activates H(+) -AT
10 We also investigated
stretch-activated Ca(2+) entry into atrial HL-1 myocytes
11 Ca(2+), and patch clamping of nuclei reveals
stretch-activated Ca(2+) permeable channels.
12 We have identified and characterized
stretch-activated Ca2+ channels from Lilium longiflorum
13 It has been widely assumed that
stretch-activated Ca2+ channels underlie this influx, bu
14 sensitive manner, suggesting the presence of
stretch-activated Ca2+ channels.
15 The presence of a
stretch-activated calcium channel in gastrointestinal sm
16 e aim of this study was to determine whether
stretch-activated calcium channels are present in gastro
17 Mechanical stimulation of
stretch-activated calcium channels is known to mediate t
18 cium transients arise from the activation of
stretch-activated calcium channels, which triggers an in
19 effects of calcium-induced contractility and
stretch-activated calcium channels.
20 Treatment of cells with the
stretch-activated cation channel (SACC) blocker Gd3+ par
21 elling-activated conductance was produced by
stretch-activated cation channel activity.
22 ed no effect on either swelling-activated or
stretch-activated cation channel activity.
23 Treatment of cells with either the
stretch-activated cation channel inhibitor GdCl3 or the
24 stola spatulata, is a selective inhibitor of
stretch-activated cation channels (SACs).
25 nical strain (CMS) increases the activity of
stretch-activated cation channels of osteoblast-like UMR
26 tment or during perinatal development, 90-pS
stretch-activated cation channels that could be blocked
27 We show that gadolinium, an antagonist for
stretch-activated cation channels, downregulates the exp
28 rains of this order are large enough to open
stretch-activated cation channels.
29 e alpha subunit of ENaC is necessary to form
stretch-activated cation channels.
30 on is diminished by pharmacological block of
stretch-activated cation-nonselective channels.
31 ogical block of ATP-inactivated potassium or
stretch-activated cation-nonselective channels.
32 d the ryanodine receptor (RyR) and (iii) the
stretch-activated channel (SAC) in both single myocytes
33 TRP channels may contribute to the increased
stretch-activated channel activity observed in mdx myofi
34 nel blocker) and gadolinium(III) chloride (a
stretch-activated channel blocker) did not alter the lev
35 hypothesis by adding gadolinium chloride (a
stretch-activated channel blocker) to the saline (0.008
36 is increased proliferation is induced by the
stretch-activated channel Piezo1 and involves calcium-tr
37 cells become too crowded, they activate the
stretch-activated channel Piezo1 to trigger extrusion of
38 tein cochlin with the cell surface bound and
stretch-activated channel TREK-1.
39 Neither
stretch-activated channel was detected in the grain prot
40 al pressure-dependent gating properties of a
stretch-activated channel with a current/voltage plot in
41 s study describes a physiologically relevant
stretch-activated channel, at both the single-channel an
42 Moreover, disruption of a
stretch-activated channel, Piezo1, in zebrafish prevents
43 MscL, a
stretch-activated channel, saves bacteria experiencing h
44 e data show that hypotonic shock generates a
stretch-activated channel-dependent calcium pulse in yea
45 GsMTx-4 indicates its possible identity as a
stretch-activated channel.
46 y acid-activated K(+) channel that is also a
stretch-activated channel.
47 ns; 2), increasing the number or activity of
stretch activated channels leads to an increase in perio
48 nce, is not dependent on Ca2+ influx through
stretch activated channels.
49 inhibited MSHA, whereas other inhibitors of
stretch-activated channels (Gd(3+), ruthenium red, SKF96
50 We tested the hypothesis that both
stretch-activated channels (SACs) and intracellular calc
51 Stretch-activated channels (SACs) have been found in myo
52 Stretch-activated channels (SACs) have been found in smo
53 Stretch-activated channels (SACs) have been shown in oth
54 ns that block voltage-gated Ca(2+) channels,
stretch-activated channels (SACs), or the Na(+)-Ca(2+) e
55 ess via integrated changes in caveolin-3 and
stretch-activated channels (SACs).
56 These results suggest that the opening of
stretch-activated channels allows ions, including Ca2+,
57 Unitary ionic currents from
stretch-activated channels and [Ca2+]i images were recor
58 l Na+ with TEA, Tris or choline, eliminating
stretch-activated channels but suggesting that if transm
59 n its gating mechanism and pharmacology from
stretch-activated channels described previously.
60 ted by a spider venom that is known to block
stretch-activated channels in animal cells, but the spon
61 ugh mechanical distention-induced opening of
stretch-activated channels in smooth muscle cells.
62 The entry of Ca2+ through
stretch-activated channels is also amplified by Ca2+ rel
63 we show that inhibiting Ca2+ influx through
stretch-activated channels using various compounds, incl
64 The
stretch-activated channels were inhibited by a spider ve
65 imply that Gd3+-sensitive, poorly selective,
stretch-activated channels were not involved.
66 omycin is not useful in the investigation of
stretch-activated channels which may underlie the myogen
67 h gadolinium (III) chloride (an inhibitor of
stretch-activated channels) only blocked the activation
68 of membrane, Ca2+-permeable cation channels (
stretch-activated channels) opened and a global increase
69 involved in creating these signal: Rho/ROCK,
stretch-activated channels, and 'Molecular Strain Gauges
70 ibited by gadolinium (Gd3+), an inhibitor of
stretch-activated channels, but is independent of extrac
71 sMTx4, a lipid-mediated modifier of cationic
stretch-activated channels, eliminated the voltage and d
72 he activation of both ERK1/2 and p38 kinase,
stretch-activated channels, small GTPase proteins, and e
73 Consistent with the presence of
stretch-activated channels, we show that Ca2+ influx is
74 ch is eliminated by gadolinium, a blocker of
stretch-activated channels.
75 , but is distinguished by signalling through
stretch-activated channels.
76 -inactivated channels was similar to that of
stretch-activated channels.
77 is abolished by gadolinium, an inhibitor of
stretch-activated channels.
78 modulates mechanosensitive (ie, swelling- or
stretch-activated)
channels was tested.
79 Here, we investigated the effects of
stretch-activated currents (ISAC) on alternans using a p
80 global changes in [Ca2+]i occurred only when
stretch-activated currents were sufficient to cause memb
81 -substrate contacts but only PIEZO1 mediates
stretch-activated currents.
82 Synchronized discharges of
stretch-activated EJPs and IJPs were preserved following
83 Although
stretch activated ERK1/2 through a Ras- and PKC classica
84 Mechanical
stretch activated ERKs, with a peak response observed at
85 PCCG-13 also significantly reduced
stretch-activated excitability in the absence of exogeno
86 nd applying weak suction evoked conventional
stretch-activated gating.
87 Cyclic
stretch activated gene expression profiles characteristi
88 Pressure-induced (-40 mm Hg) membrane
stretch activated ion channels in arterial myocyte cell-
89 biological phenomena, notably the gating of
stretch activated ion channels.
90 d in Ussing chambers) revealed 2-fold higher
stretch-activated ion channel conductances in response t
91 expressed in Escherichia coli, MSL1 forms a
stretch-activated ion channel with a slight preference f
92 t a functional interaction between TRPV4 and
stretch-activated ion channels (SACs) is involved in thi
93 We hypothesized that
stretch-activated ion channels (SACs) mediated this incr
94 ed by inhibiting focal adhesion signaling or
stretch-activated ion channels and is independent of cel
95 A calcium influx through
stretch-activated ion channels and the detachment of adh
96 Recently, the Piezo family of
stretch-activated ion channels has been identified as ge
97 Functionally significant
stretch-activated ion channels have been clearly identif
98 The transduction process involves integrins,
stretch-activated ion channels, and IL-4.
99 duce calcium entry (including Gd3+, to block
stretch-activated ion channels, and nifedipine) abolishe
100 Stretch-activated ion channels, caveolae, integrins, cad
101 f NCM to support mechanotransduction through
stretch-activated ion channels.
102 bone cells independently of Ca(2+) flux and
stretch-activated ion channels.
103 ce is the activation of mechanosensitive (or
stretch-activated)
ion channels, and a number of mechano
104 ILOT is not voltage- or
stretch-activated,
it has a characteristically long open
105 TREK-1 encodes a component of the
stretch-activated K(+) conductance in smooth muscles and
106 In addition, we find a
stretch-activated K+ channel as well as a spontaneous K+
107 cells expressing in the basolateral membrane
stretch-activated K+ channels demonstrable by the cell-a
108 characterize the expression and function of
stretch-activated K2P channels in the human bladder and
109 otransduction associated with the changes in
stretch-activated K2P channels may underlie myogenic bla
110 X-ray diffraction "movies" from sinusoidally
stretch-activated Lethocerus muscles.
111 rum of ALI models and in cytokine- or cyclic
stretch-activated lung microvascular endothelium.
112 found evidence for myocyte protection via a
stretch-activated mechanism.
113 We describe a method to investigate
stretch-activated mechanotransduction in sensory nerves
114 This interaction may serve as a mechanism of
stretch-activated muscle contraction, and this system co
115 NLP-12 expression is limited to a single
stretch-activated neuron, DVA.
116 Surprisingly, the
stretch-activated NF-kappaB and AP-1 signaling pathways
117 A
stretch-activated,
nifedipine-sensitive calcium channel
118 ompletely blocked the swelling-activated and
stretch-activated nonselective cation channel response t
119 s respond to repetitive strain by activating
stretch-activated,
nonselective cation channels (SA-CAT)
120 Bundles of 8-12 fibers were
stretch-activated on SRS synchrotron x-ray beamline 16.1
121 t a Ca(2+) capacitor discharged at low pH by
stretch-activated plasma membrane H(+)-ATPases, hence a
122 However, transverse
stretch activated Ras-GTP, Raf-1, and Erk1/2 proteins, w
123 tivation of NF-kappaB involves activation of
stretch-activated (
SA) channels and the production of fr
124 ouse lung, where elevated CO2 also inhibited
stretch-activated shedding of the ADAM17 substrate TNFR1
125 The
stretch-activated substrate of Fyn and c-Src, p130Cas, i
126 We conclude that
stretch-activated tension of IFM is produced by cross-br
127 on saturated at slightly lower [Ca(2+)] than
stretch-activated tension, such that as [Ca(2+)] increas
128 Both calcium-activated and
stretch-activated tensions increased with increasing [Ca
129 Stretch activated the IkappaB-NF-kappaB pathway, and NF-
130 Animal data suggest that
stretch-activated two-pore-domain (K2P) K(+) channels pl
131 argeted nanoparticles can penetrate and bind
stretch-activated vascular smooth muscles in the media a
132 Arachidonic acid, proton and membrane
stretch activated,
whereas dibutyryl-cAMP inhibited all