ライフサイエンスコーパス: striosome

1 clustered arrangements typical of developing striosomes.

2 ites with respect to mu-opioid receptor-rich striosomes.

3 ng rats to search for selective functions of striosomes.

4 f layer V and in medium spiny neurons within striosomes.

5 predominant activation of neurons located in striosomes.

6 al matrix and extremely few were seen in the striosomes.

7 lateral hypothalamus, ventral striatum, and striosomes.

8 labeling corresponded to the calbindin-poor striosomes.

9 rmore, we found an imbalance in the striatal striosome and matrix compartments in early stages of the

10 The striosome and matrix compartments of the striatum are cl

11 mical and functional components, such as the striosome and matrix compartments.

12 e channel agonists was targeted to opposite (striosome and matrix) cellular phenotypes.

13 iatal direct-pathway neurons enriched in the striosome and nucleus accumbens, in an otherwise MOR-nul

14 hemical compartmentalization of areas termed striosomes and extrastriosomal matrix.

15 he fundamental division of the striatum into striosomes and extrastriosomal matrix.

16 Neurons in both striosomes and matrix responded to reward-predicting cue

17 vo imaging to determine the contributions of striosomes and matrix to striatal circuit function.

18 Dopamine transmission occurs throughout striosomes and matrix, and is reported to be modulated b

19 tments within the mammalian striatum, termed striosomes and matrix, which express mu-opioid receptors

20 ifferentially affects the dopamine output in striosomes and matrix.

21 f humans and other species, dividing it into striosomes and matrix.

22 g altered patterns of early-gene response in striosomes and matrix.

23 s a heterogeneous structure characterized by striosomes and matrix.

24 y distinct compartments of the striatum, the striosomes and the extrastriosomal matrix.

25 ion of rat corticostrial axons in the patch (striosome) and matrix compartments of the neostriatum wa

26 in immunostaining corresponded to the patch (striosome) and matrix compartments within the striatum.

27 two striatal tissue compartments, the patch (striosome) and matrix, were analyzed separately.

28 ed into two compartments named the patch (or striosome) and the matrix.

29 llaries were found in the matrix compared to striosomes, and a likely correspondence exists between h

30 striatum, whereas the latter indicates that striosomes are more lattice-like than their spatial vari

31 he endogenous opioid enkephalin, patches (or striosomes) are limbic-associated subcompartments enrich

32 tdTomato-labeled neuropil that correspond to striosomes as verified immunohistochemically.

33 at altered excitation-inhibition dynamics of striosome-based circuit function could be an underlying

34 ted in either the matrix or along the matrix-striosome border.

35 ely either in the matrix or along the matrix-striosome border.

36 ing findings: 1) individual bifurcation-free striosome branches are 355 +/- 108.5 microm in diameter

37 and are both lognormally distributed; and 2) striosome branches exhibit three pronounced orientation

38 stantially increases the dopamine release in striosomes, but not in matrix.

39 matrix axis: dopamine release was boosted in striosome centers, diminished in striosomal-matrix borde

40 antly higher levels of SOD than those in the striosome compartment.

41 these axons converge on a small fraction of striosome compartments restricted to the dorsolateral st

42 endrites was only observed in the rim of the striosome compartments.

43 y timed inhibitory conditioning (through the striosomes), control SNc responses.

44 ly to reinforcement and decision-making, the striosome-dendron bouquets could be critical to dopamine

45 We suggest that the striosome-dendron bouquets form specialized integrative

46 e striosome-dendron formations, here termed "striosome-dendron bouquets," likely represent subsystems

47 Thus, these striosome-dendron formations, here termed "striosome-den

48 tum is divided into a labyrinthine system of striosomes embedded in a surrounding matrix compartment.

49 ion cascade, matrix-enriched CalDAG-GEFI and striosome-enriched CalDAG-GEFII (also known as RasGRP),

50 The amount by which activation in the striosomes exceeded activation in the matrix predicted t

51 Other functional compartments, such as striosomes, extrastriosomal matrix and matrisomes, also

52 The striosomes form a connected reticulum made up of two dis

53 ate that striatonigral fibers originating in striosomes form highly unusual bouquet-like arborization

54 s observed in two striatal compartments, the striosomes, identified as regions of dense [(3)H]naloxon

55 rceived variable spatial organization of the striosomes in primates belies many invariant features th

56 ment in juvenile monkeys but more intense in striosomes in the adult caudate, suggesting that m1 expr

57 is likely to be the origin of innervation to striosomes in the caudoputamen disappears between P21 an

58 ract with timed inhibitory inputs from model striosomes in the ventral striatum to regulate dopamine

59 n unclear, but the anatomical connections of striosomes indicate their relation to emotion-related br

60 in the striatum by means of image analysis, striosome-matrix boundaries by [3H]naloxone binding, and

61 ine transmission is modulated differently in striosome-matrix compartments by substance P.We paired d

62 indicate a functionally distinct zone at the striosome-matrix interface, which may have key impacts o

63 s suggest that, in addition to the classical striosome-matrix organization visible in the dorsal caud

64 bution of all markers followed the classical striosome/matrix organization as previously reported.

65 to be more vulnerable than interneurons and striosome neurons more vulnerable than matrix neurons to

66 of high metabolic activity in the matrix, in striosomes, or in both.

67 clear microarchitectures, such as the matrix-striosome organization of the basal ganglia or the patch

68 s several quantitative invariant measures of striosome organization, including the following findings

69 region, which is enriched for markers of the striosome (patch) compartment.

70 correspond with increased activity of their striosome-predominant striatal projection neuron targets

71 Given evidence that striosomes receive input from cortical regions related t

72 riatum while tending to potentiate it in the striosomes, resulting in an extremely patchy pattern of

73 By contrast, in the core of the striosomes, SPR labeling was sparse and SP staining inte

74 sentations in the forebrain and suggest that striosome-targeting corticostriatal circuits can underli

75 mu opioid receptors are concentrated within striosomes that receive inputs from limbic regions of pr

76 ed activation of neurons located in striatal striosomes that substantially exceeds that of the surrou

77 ability of neurons in the matrix, versus the striosomes, to early excitotoxin-induced DNA damage in r

78 on is variable, morphometric analysis of the striosomes, utilizing skeletonizations, reveals several

79 reconstruction and morphometric analysis of striosomes was carried out in macaque monkeys by using i

80 putamen, ChAT-staining was less intense, and striosomes were delineated primarily by unstained fiber

81 Striosomes were discovered several decades ago as neuroc

82 n was not due to premature cell death in the striosomes which contained numerous unlabeled neurons.

83 Binding is absent from the striosomes, which were identified by mu-opioid receptor