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1 is complex (TSC) genes, and recruit abundant stromal cells.
2 ntified CD40L as a novel GLI2 target gene in stromal cells.
3 upon decidualization of primary endometrial stromal cells.
4 ell types, including epithelial, immune, and stromal cells.
5 sistant disease in cocultures of bone marrow stromal cells.
6 ack of growth factors secreted from adjacent stromal cells.
7 by coculture with developmentally supportive stromal cells.
8 e repertoire of genes specifically in thymic stromal cells.
9 l activation of CD40L in bone marrow-derived stromal cells.
10 d disease and in the presence of bone marrow stromal cells.
11 in vivo is TLR independent and emanates from stromal cells.
12 ow toxicity to normal lymphocytes and normal stromal cells.
13 gnaling within both tumor cells and adjacent stromal cells.
14 mice developed into tumors containing green stromal cells.
15 previously demonstrated in human bone marrow stromal cells.
16 ed extensively in human pancreatic tumor and stromal cells.
17 HIF-1alpha, and aromatase expression in LFS stromal cells.
18 itochondria from murine or human bone marrow stromal cells.
19 2D)) also regulates tumor cell signaling via stromal cells.
20 PKM2 suppressed aromatase expression in LFS stromal cells.
21 ne evasion, and co-option of other tumor and stromal cells.
22 mune cells that also localize near senescent stromal cells.
23 progenitors, osteocytes and CXCL12-producing stromal cells.
24 cose media increased adhesion to bone marrow stromal cells.
25 oncomitant knockdown of Atg7 in both AML and stromal cells.
26 e and hyaluronic acid) and mouse bone marrow stromal cells.
27 ion of ANG-2 expression from macrophages and stromal cells.
28 gration, localization, and interactions with stromal cells.
29 ct contact between the malignant B cells and stromal cells.
30 t C3aR expression and function in immune and stromal cells.
31 l role in the decidualization of endometrial stromal cells.
32 en deposition in the bone marrow mesenchymal stromal cells.
33 ant B cells cocultured with CD40L-expressing stromal cells.
34 by a subpopulation of ICAM1(+) perivascular stromal cells.
35 ent cytolysin, pyolysin (PLO), which targets stromal cells.
36 n of IL-17RA-expressing podoplanin(+)CD31(-) stromal cells, a profile associated with fibroblastic re
37 , these data suggest that CXCL12 secreted by stromal cells activates invasiveness of prostate cancer
38 tissue contains adipose-derived mesenchymal stromal cells (ADSCs) that have regenerative and reparat
39 d by genetic deletion ofCcl19 Thus, ACKR4 on stromal cells aids the egress of APCs from mouse skin, a
40 t trans-cellular regulation originating from stromal cells and affect tumour cells, highlighting the
41 MI-2 abrogated survival signals provided by stromal cells and BCR cross-linking and was effective ag
44 and breast cancer clusters recruit activated stromal cells and guide the sprouting of endothelial cel
45 pathways mediated by factors secreted by BM stromal cells and involved a switch from BCL2 to BCLXL-d
46 ne CXCL13 is expressed by FDC and follicular stromal cells and modulates the homing of CXCR5-expressi
49 on upregulates Tgfbeta signaling in prostate stromal cells and promotes progression of a reactive str
51 th decreases MM cell adhesion to bone marrow stromal cells and reduces MM cell homing to the bone mar
52 t, which contains adjacent epithelial cells, stromal cells and smooth muscle cells, and soluble and c
53 ofibroblasts derive from Gli1(+) mesenchymal stromal cells and that a Gli inhibitor targets them for
54 s showed that the expression of caldesmon in stromal cells and the expression of osteopontin in both
56 repressor, is down-modulated in skin cancer stromal cells, and Atf3 knockout mice develop aggressive
57 ation through endothelial cells, adhesion to stromal cells, and cell proliferation and display an inc
58 interactions between breast cancer cells and stromal cells, and iii) cancer-regulated angiogenesis.
59 The complex interplay between cancer cells, stromal cells, and immune cells in the tumor microenviro
60 of the ectonucleotidase CD73 by tumor cells, stromal cells, and immune cells is associated in cancer
61 and gradually degrade endosteal endothelium, stromal cells, and osteoblastic cells, whereas central m
62 ntiation and expansion of immune-suppressive stromal cells, and remodels the metabolic landscape to s
64 interactions with developmentally supportive stromal cells, and that the relative motility of NK cell
65 ensional culture, with or without supporting stromal cells, and under these conditions they give rise
66 requirement maps to IL-4Ralpha expression by stromal cells, and we provide evidence that it regulates
68 xtensively, the contribution of fibroblastic stromal cells as portals of entry into the CNS was only
69 L12 axis was amplified in activated lymphoid stromal cells as shown in our in vitro model of human ly
71 uingly, increased expression of Arf in tumor stromal cells, as in tumor keratinocytes themselves, con
72 port the application of adipose-derived stem/stromal cells (ASCs) for engineering the pulmonary vascu
73 w that MDM cells contribute to the postnatal stromal cells at the dorsal aspect of the prostatic uret
74 y, tolerability, and efficacy of mesenchymal stromal cell-based therapy in pilot clinical trials, inc
77 dies have shown that bone marrow mesenchymal stromal cells (BM-MSC) protect AML blasts from spontaneo
78 Previously, we demonstrated that bone marrow stromal cell (BMSC) and CB-BF pellet cultures make carti
79 tes superoxide, which stimulates bone marrow stromal cells (BMSC) to AML blast transfer of mitochondr
80 ifference in the metabolomics of bone marrow stromal cells (BMSCs) derived from hyperglycaemic (type
81 ed osteogenic differentiation of bone marrow stromal cells (BMSCs) of Bag-1(+/-) (heterozygous) femal
86 n cancer cells themselves and between cancer-stromal cells by secreted signaling molecules (ligands)
87 selectively autoamplify its own synthesis in stromal cells by signaling transcriptional repression of
88 nvincingly in rodent models that mesenchymal stromal cells can prolong solid organ graft survival and
89 1+/-0.002; P<0.001), multipotent mesenchymal stromal cell colony maximum (estimate+/-SE, 0.01+/-0.002
90 .01+/-0.002; P=0.002) in BM, and mesenchymal stromal cell colony maximum in PB (estimate+/-SE, 0.02+/
91 l layers were significantly reduced, and the stromal cell compartment did not expand and became atrop
92 Recapitulating tissue ECM composition and stromal cell composition enhanced cancer cell invasion.
94 ion, maintenance, and metastatic progression.Stromal cells contribute to tumor development but the me
95 ocytes, mucosal endothelium, epithelium, and stromal cells controls leukocyte recruitment and microen
98 eciprocal interactions between malignant and stromal cells create a local microenvironment that foste
99 cale cell assemblages of encapsulated marrow stromal cells cultured in microwells, osteogenic differe
103 ered chemokine receptor CXCR7 and its ligand stromal cell-derived factor (SDF)-1 are known to be invo
104 (P = 0.04), stem cell factor (P = 0.05), and stromal cell-derived factor 1 (P = 0.03) compared to tho
106 nly in muscles atrophying because of cancer: stromal cell-derived factor 1 (SDF1), adenylate cyclase
107 on 1 (PLCepsilon1) as a crucial regulator of stromal cell-derived factor 1 alpha (SDF-1alpha)-induced
109 <em>CXCL12</em>, which encodes a chemokine, stromal cell-derived factor 1, that is expressed in card
111 r adhesion molecule 1; interleukin 6 [IL-6]; stromal cell-derived factor 1; tissue inhibitor of metal
112 of vascular endothelial growth factor D and stromal cell-derived factor 1alpha (P = .037 and .025, r
113 gration toward formyl-Met-Leu-Phe (fMLP) and stromal cell-derived factor 1alpha (SDF-1alpha) as well
115 r pathway may participate, together with the stromal cell-derived factor-1 (SDF-1)/C-X-C chemokine re
116 L5551 inhibited CXCR4 binding to its ligand, stromal cell-derived factor-1alpha, and reduced hypoxia-
117 ived factor-1alpha, and reduced hypoxia- and stromal cell-derived factor-1alpha-mediated migration do
118 ly replication of certain prion strains upon stromal cell-derived follicular dendritic cells (FDC) in
119 histone H3 lysine 27 (H3K27me3) in decidual stromal cells dictate both elements of pregnancy success
120 ritic cells (DCs), rather than TECs or other stromal cells, disrupts the S1P gradient, preventing egr
122 ection of cytokines that improve mesenchymal stromal cell engraftment into the heart both in normal c
123 In series 2, umbilical cord-mesenchymal stem/stromal cells enhanced animal survival and decreased alv
125 signaling mediated IL-4-induced endometrial stromal cell (ESC) proliferation ex vivo, and that genit
126 t IRF-1 restricts CHIKV and RRV infection in stromal cells, especially muscle cells, and that this co
127 nsduction of bone marrow-derived mesenchymal stromal cells ex vivo, followed by intramyocardial cell
131 efficacy of >98% in pre-purified mesenchymal stromal cells, extracted from human dental pulp, with no
132 emonstrate that EAV has specific tropism for stromal cells (fibrocytes and possibly tissue macrophage
135 ps have observed increased nuclear CTNNB1 in stromal cells from a high frequency of MDS/AML patients,
137 xeno-free conditions, with mesenchymal stem/stromal cells from human bone marrow, in a rat model of
139 rotein 1 (HAPLN1) is produced in bone marrow stromal cells from MM patients, is detected in patients'
140 NA methylome analysis of bone marrow-derived stromal cells from myelodysplastic syndrome (MDS) patien
143 n of biallelic RELA expression in protecting stromal cells from TNF-mediated cell death, thus delinea
147 who received umbilical cord-mesenchymal stem/stromal cells had improvements in oxygenation, respirato
148 llicular helper (TFH) cells and infiltrating stromal cells have been shown to favor FL B-cell growth,
149 l line M2-10B4 and human primary bone marrow stromal cells have confirmed that NELL-1 enhances BMP2-i
152 of GPR64 was increased in human endometrial stromal cells (hESCs) during in vitro decidualization.
155 ere we discuss how EVs released by cancer or stromal cells impact the proliferation, differentiation,
156 logue octreotide induces apoptosis in VHL-HB stromal cells in a dose-dependent fashion by BAX - caspa
157 te responses in lymph nodes, but the role of stromal cells in adipose tissue inflammation is unknown.
158 vered a pathogenic function for fibroblastic stromal cells in alloimmune reactivity that can be disso
162 llular communication between tumor cells and stromal cells in local and distant microenvironments.
163 ectin stimulation of alpha5beta1 integrin on stromal cells in PDA results in reduced angiogenesis and
166 el function for podoplanin on periarteriolar stromal cells in the bone marrow: promoting megakaryocyt
167 Recent research has highlighted the role of stromal cells in the generation and persistence of chron
168 unofluorescence indicated that podoplanin(+) stromal cells in the red pulp were the primary producers
169 resent over 90% of CRC, RSPO3 is produced by stromal cells in the tumor microenvironment and the acti
171 CXCL12 and reducing adhesion to mesenchymal stromal cells in vitro We also found that HIF-2alpha str
172 evaluate the effect of CXL on human corneal stromal cells in vitro, we developed a 3-D in vitro CXL
174 and other molecules between transformed and stromal cells, including fibroblasts, endothelial and im
175 Interestingly, coculture of AML cells with stromal cells increased autophagy and chemoresistance in
177 utilize pH modulation to recruit associated stromal cells, induce partial reprogramming of tumor-ass
178 tumour tissue, independent of proliferation, stromal cell infiltration and tumour characteristics.
179 , such as cancer-immune system interactions, stromal cell interactions, oncoviruses, and sensitivity
180 amic scaffolds coated with human mesenchymal stromal cells into immune-deficient mice, we were able t
181 nous injection of singly encapsulated marrow stromal cells into mice delays clearance kinetics and su
182 ed mice receiving human amniotic mesenchymal stromal cells intravenously or intracerebroventricularly
184 pproach in a 3D carrier scaffold seeded with stromal cells is an effective in vivo niche model for st
185 ion of the Hh effector Smoothened (Smo) from stromal cells is associated with the loss of osteoblasto
186 pid mediator (LM) profiles of tendon-derived stromal cells isolated from healthy donors and patients
187 d the number of bone marrow mesenchymal stem/stromal cells, likely due to decreased expression of PDG
188 In vitro studies using the mouse bone marrow stromal cell line M2-10B4 and human primary bone marrow
189 ls was reduced in the presence of lymph node stromal cells (LNSCs) from NOD mice but not from mice la
195 e been investigated for inducing mesenchymal stromal cell (MSC) differentiation towards the smooth mu
197 echanisms underlying OA-mediated mesenchymal stromal cell (MSC) osteogenic differentiation are not kn
199 both ex vivo bone marrow-derived mesenchymal stromal cells (MSC) and in vitro 3T3-L1 preadipocytes si
203 been suggested to originate from mesenchymal stromal cells (MSC), but their relationship with MSCs is
209 urine models of BMF that Gli1(+) mesenchymal stromal cells (MSCs) are recruited from the endosteal an
211 esicles (EVs) isolated from mesenchymal stem/stromal cells (MSCs) contribute to recovery of damaged t
212 -term passaged (P10) aging human mesenchymal stromal cells (MSCs) could be used for bone tissue regen
213 ed that coculture of islets with mesenchymal stromal cells (MSCs) enhanced islet insulin secretory ca
214 on for a first-in-human trial of mesenchymal stromal cells (MSCs) for septic shock, we applied system
215 cell-based therapy options, mesenchymal stem/stromal cells (MSCs) from bone marrow, adipose tissue, a
216 the presence of multipotent mesenchymal stem/stromal cells (MSCs) in non-carcinogenic thyroids and pa
222 these issues by using human mesenchymal stem/stromal cells (MSCs) that produce EVs when incubated in
226 zed Notch-mediated immunopathogenic role for stromal cell niches in secondary lymphoid organs after a
227 Since in patient-derived xenografts (PDXs) stromal cells of the human tumour are substituted by mur
228 duced GPR64 expression in the epithelial and stromal cells of the uterus in ovariectomized wild-type
230 and hypoxic signaling pathways in tumor and stromal cells on each step of the metastatic cascade.
231 omal cells with bone marrow-mesenchymal stem/stromal cells on physiologic indices of lung injury, cel
232 ryopreserved umbilical cord-mesenchymal stem/stromal cells on survival, as well as measures of injury
234 ion at all gestational ages, associated with stromal cells or near blood vessels, but was absent in t
235 ion and reduced G-CSF expression in CRTC2/3m stromal cells, our results demonstrate how cross-couplin
241 l cells (BMSCs), a major type of multipotent stromal cells, produces pain relief (antihyperalgesia) t
243 o-free human umbilical cord-mesenchymal stem/stromal cells reduce the severity of rodent E. coli-indu
246 des evidence that inhibiting FDFT1 increases stromal cell resilience to a cholesterol-dependent cytol
248 s underlying the crosstalk between tumor and stromal cells revealed that melanoma cells produced PDGF
249 the functional capacity of tumor-associated stromal cells revealed that myeloid cells, primarily DCs
252 ibrosis thought to be induced by mesenchymal stromal cells stimulated by overproduced growth factors.
253 ailable data on culture-expanded mesenchymal stromal cells tested in renal transplantation, AKI, and
254 us hiPSCs as source and generates a range of stromal cells that co-develop with parenchymal cells to
255 is study, we investigate whether mesenchymal stromal cells that constitute a supportive microenvironm
256 itioning within the tissue are controlled by stromal cells that construct the barriers of the CNS.
257 r and molecular specialization within thymic stromal cells that enables their regulation of specific
258 mus, Nes expression was restricted to thymic stromal cells that expressed cerebellar degeneration-rel
259 -chip" platform incorporates human tumor and stromal cells that grow in a 3D extracellular matrix and
260 ntly, 17f had minimal effects on bone marrow stromal cells that play vital functions in the microenvi
262 of Dll1 and Dll4 in subsets of fibroblastic stromal cells that were derived from chemokine Ccl19-exp
264 nt of the safety and efficacy of mesenchymal stromal cell therapies to allow the translation of this
265 d promising results for HSCT and mesenchymal stromal cell therapy as alternatives to systemic therapi
267 or patients with fistulizing CD, mesenchymal stromal cell therapy deposits MSCs locally, into fistuli
268 cell transplantation (HSCT) and mesenchymal stromal cell therapy have been proposed for patients wit
270 nd stromal cells increased IL-8 secretion by stromal cells through cell-cell adhesion and soluble fac
271 ontal transfer of genetic material from host stromal cells to cancer cells triggers the evolution of
272 ommunication bridges between tumor cells and stromal cells to create a permissive microenvironment fo
273 iptional effector, acts within mouse mammary stromal cells to direct a hormone-responsive niche signa
276 otential for umbilical cord-mesenchymal stem/stromal cells to reduce E. coli-induced oxidant injury.
279 nt, endothelial cells (ECs) are an important stromal cell type interacting with malignant cells to fa
281 ontent of many tumours associated immune and stromal cell types, their therapeutically relevant ratio
283 e separation of viable from non-viable human stromal cells using remote dielectrophoresis, in which a
285 ted that regulated activation of TGF-beta by stromal cells was able to directly control epithelial re
288 tment of cardiotrophin-1-treated mesenchymal stromal cells was consequent to signal transducer and ac
289 r, we found that expression of Hsp70 in host stromal cells was essential to support tumor growth.
291 Carbon monoxide preconditioned mesenchymal stromal cells were also able to alleviate organ injury,
292 gen receptor alpha (Esr1) from mouse uterine stromal cells, where the embryo is implanted during preg
293 alized channels lined with human bone marrow stromal cells, which adopt a mural cell-like phenotype t
294 imulated the production of the CXCL13 by TME stromal cells, which in turn promoted ILC3-stromal inter
295 n nonhematopoietic, nonepithelial intestinal stromal cells, which respond to OSM by producing various
296 of a synapse between developing NK cells and stromal cells, which we term the developmental synapse.
297 rgeted disruption of both CRTC2 and CRTC3 in stromal cells with a mesenchymal Prx1-Cre transgene also
298 ryopreserved umbilical cord-mesenchymal stem/stromal cells with bone marrow-mesenchymal stem/stromal
299 , Chung and colleagues present evidence that stromal cells within lymphoid tissue express the Notch l
300 esident B cells account for more than 20% of stromal cells within visceral adipose tissues; however,
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