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1 mote repair and regeneration in concert with stromal cell derived factor.
2 or CXCR4 to induce chemotaxis in response to stromal cell derived factor 1 and abolished the activati
3 orphism in the 3' untranslated region of the stromal cell-derived factor 1 (also called pre-B-cell-st
4 (P = 0.04), stem cell factor (P = 0.05), and stromal cell-derived factor 1 (P = 0.03) compared to tho
5 nished hypoxia response, including decreased stromal cell-derived factor 1 (P<0.005) and vascular end
6 cells express alpha-smooth muscle actin and stromal cell-derived factor 1 (SDF-1) and are tumorigeni
7 study was to analyze the role of a chemokine stromal cell-derived factor 1 (SDF-1) and its receptor C
8 bular joint (TMJ) and to explore the role of stromal cell-derived factor 1 (SDF-1) and regulated on a
9 ation-dependent chemotaxis to their ligands, stromal cell-derived factor 1 (SDF-1) and VCAM-1, which
11 hibit significantly enhanced chemotaxis to a stromal cell-derived factor 1 (SDF-1) gradient and adher
12 the chemokine receptor CXCR4 by its agonist stromal cell-derived factor 1 (SDF-1) has been associate
13 wn that T cells move away from the chemokine stromal cell-derived factor 1 (SDF-1) in a concentration
16 ic chondrocytes, while its ligand, chemokine stromal cell-derived factor 1 (SDF-1) is expressed in th
19 scular endothelial growth factor (VEGF), and stromal cell-derived factor 1 (SDF-1) than cells from un
21 ndertaken to investigate the hypothesis that stromal cell-derived factor 1 (SDF-1), a CXC chemokine (
23 opoietic progenitors, it (1) potentiates the stromal cell-derived factor 1 (SDF-1)-dependent chemotax
24 dly and dose-dependently inhibited basal and stromal cell-derived factor 1 (SDF-1)-induced BMC migrat
25 ween GPI+ and GPI(neg) NK cells and impaired stromal cell-derived factor 1 (SDF-1)-induced chemotaxis
27 tumor cells through their ability to secrete stromal cell-derived factor 1 (SDF-1); CAFs promote angi
28 ating evidence indicates that interaction of stromal cell-derived factor 1 (SDF-1/CXCL12 [CXC motif,
30 he hypothesis that chemokines in general and stromal cell-derived factor 1 (SDF-1; CXCL12) in particu
33 CD20 is directly upregulated by CXCR4 ligand stromal cell-derived factor 1 (SDF-1alpha, CXCL12) produ
34 afish has shown that the interaction between stromal cell-derived factor 1 (SDF1) and its G-protein-c
36 1-deficient MKs in response to a gradient of stromal cell-derived factor 1 (SDF1), a major chemokine
37 nly in muscles atrophying because of cancer: stromal cell-derived factor 1 (SDF1), adenylate cyclase
38 C chemokine ligand 12 (CXCL12, also known as stromal cell-derived factor 1 [SDF-1]), a chemokine prev
39 on 1 (PLCepsilon1) as a crucial regulator of stromal cell-derived factor 1 alpha (SDF-1alpha)-induced
40 hic factor (GDNF), sonic hedgehog (Shh), and stromal cell-derived factor 1 alpha (SDF1alpha), providi
41 y of CXCR4 antibodies to block chemotaxis to stromal cell-derived factor 1 alpha and to inhibit HIV-1
42 that interactions between the CXC chemokine stromal cell-derived factor 1 and its receptor CXC chemo
43 ith significantly upregulated mRNA levels of stromal cell-derived factor 1 and platelet-derived growt
44 many T lymphocytes migrate away than towards stromal cell-derived factor 1 and their directional migr
45 eased vascular endothelial growth factor and stromal cell-derived factor 1 expression in fibroblasts;
46 s provided suggesting that downregulation of stromal cell-derived factor 1 expression in the bone mar
48 rn to that of CD34(+) cells, and opposite to stromal cell-derived factor 1 plasma levels and correspo
49 ced molecule 1 ligand chemokine) and CXCL12 (stromal cell-derived factor 1) have not been established
50 inting to the potential role of a chemokine (stromal cell-derived factor 1) in lymphomagenesis, and s
51 Recent progress has implicated CXCR4-SDF1 (stromal cell-derived factor 1) signaling in regulating n
52 ested the hypothesis that blockade of SDF-1 (stromal cell-derived factor 1), a key stem cell mobilize
54 Chemokines such as CXCL12, previously called stromal cell-derived factor 1, are known to activate cel
55 upernatants but no increase in the cytokines stromal cell-derived factor 1, macrophage inflammatory p
56 and RYR3 that occurred after treatment with stromal cell-derived factor 1, macrophage-inflammatory p
57 <em>CXCL12</em>, which encodes a chemokine, stromal cell-derived factor 1, that is expressed in card
58 and increased renal expression of its ligand stromal cell-derived factor 1, thus favoring mobilizatio
59 actors, transforming growth factor alpha and stromal cell-derived factor 1, was not affected by 100 p
60 sustained delivery of a synthetic analog of stromal cell-derived factor 1-alpha (engineered stromal
62 cell subsets revealed that migration toward stromal cell-derived factor 1/CXC ligand 12 (SDF-1/CXCL1
63 sed CXCR4-mediated chemotaxis in response to stromal cell-derived factor 1/CXCL12 and abolished the p
65 hypoxic preconditioning are mediated by the stromal cell-derived factor 1/CXCR4 axis, and that thera
67 hematopoietic compartment is associated with stromal cell-derived factor 1/CXCR4-dependent vasculogen
68 onstitutively expressed in the CNS (known as stromal cell-derived factor 1; SDF-1), regulates cleavag
69 r adhesion molecule 1; interleukin 6 [IL-6]; stromal cell-derived factor 1; tissue inhibitor of metal
70 tor-alpha; chemokine (C-X-C motif) ligand 1; stromal cell-derived factor 1; transforming growth facto
72 molecule E-selectin and the chemoattractant stromal-cell-derived factor 1 (SDF-1) in discrete, disco
73 selective activation of chemokines, such as stromal-cell-derived factor 1 (SDF-1), macrophage inflam
75 fibroblasts to secrete much higher levels of stromal-cell-derived factor 1 and vascular endothelial g
79 The C-X-C chemokine receptor type 4 (CXCR4)/stromal cell derived factor-1 (SDF-1 or CXCL12) interact
81 ypoxia-inducible factor-1alpha (HIF-1alpha), stromal cell derived factor-1 (SDF-1), matrix metallopro
82 The chemokine receptor CXCR4 and its ligand, stromal cell derived factor-1 alpha (SDF1 alpha) regulat
85 to activate fibrocytes, probably by inducing stromal cell-derived factor-1 (also termed CXCL12), one
86 is usually stimulated by chemokines such as stromal cell-derived factor-1 (CXCL12) acting via G prot
87 ed that GC T cells would actively migrate to stromal cell-derived factor-1 (CXCL12), the CXCR4 ligand
90 ment, where evidence points to the chemokine stromal cell-derived factor-1 (SDF-1 or CXCL12; expresse
92 the interaction between the HIF-1-dependent stromal cell-derived factor-1 (SDF-1) and its receptor,
94 ression of both the EPC mobilizing chemokine stromal cell-derived factor-1 (SDF-1) and of vascular ep
108 Based on a short hairpin RNA library and stromal cell-derived factor-1 (SDF-1) migration screenin
110 tion of chemokines, the role of signaling by stromal cell-derived factor-1 (SDF-1) through its recept
111 ly and reversibly antagonizes the binding of stromal cell-derived factor-1 (SDF-1) to its receptor CX
114 higher plasma levels of the chemokine CXCL12/stromal cell-derived factor-1 (SDF-1) were achieved in a
115 eta-1, can strikingly stimulate secretion of stromal cell-derived factor-1 (SDF-1), also known as CXC
116 flammatory mediators, such as the chemokine, stromal cell-derived factor-1 (SDF-1), and factors that
117 ), a HIF-1alpha-independent up-regulation of stromal cell-derived factor-1 (SDF-1), as well as endoth
118 stology and immunohistochemical detection of stromal cell-derived factor-1 (SDF-1), beta-actin, vascu
119 receptor 4 (CXCR4), the primary receptor for stromal cell-derived factor-1 (SDF-1), is involved in bo
120 Here, we show that its cognate chemokine, stromal cell-derived factor-1 (SDF-1), promotes the surv
122 endent cytokine transcription in response to stromal cell-derived factor-1 (SDF-1), the sole chemokin
124 stimulated immature B cells are defective in stromal cell-derived factor-1 (SDF-1)-induced calcium mo
125 al evaluation, 32 efficiently inhibits CXCR4/stromal cell-derived factor-1 (SDF-1)-mediated modulatio
127 r pathway may participate, together with the stromal cell-derived factor-1 (SDF-1)/C-X-C chemokine re
129 cells were found to upregulate production of stromal cell-derived factor-1 (SDF-1)/CXCL12 in human fi
130 ween the upregulation of the chemoattractant stromal cell-derived factor-1 (SDF-1)/CXCL12 in the inju
133 between the chemokine receptor 4 (CXCR4) and stromal cell-derived factor-1 (SDF-1, also known as CXCL
139 CXCR4 is a chemokine receptor that binds stromal cell-derived factor-1 (SDF-1; also known as CXCL
140 chemokine receptor 4 (CXCR4) and its ligand, stromal cell-derived factor-1 (SDF-1alpha or CXC chemoki
145 R7 by their shared cognate chemokine ligand (stromal cell-derived factor-1 [SDF-1]) in Stx-mediated p
146 4) for the chemokine (C-X-C motif) ligand 12/stromal cell-derived factor-1 alpha (CXCL12/SDF-1 alpha)
147 ted by the chemokine (C-X-C motif) ligand 12/stromal cell-derived factor-1 alpha (CXCL12/SDF-1) via t
148 ross TNF-treated EC monolayers overlaid with stromal cell-derived factor-1 alpha (SDF-1 alpha) and su
149 ence stimulates proliferation, survival, and stromal cell-derived factor-1 alpha (SDF-1 alpha)-induce
150 ed chemotactically to their cognate ligands, stromal cell-derived factor-1 alpha and secondary lympho
151 t to be involved in hemopoietic cell homing, stromal cell-derived factor-1 and its receptor CXC chemo
152 imals have increased chemotactic response to stromal cell-derived factor-1 and macrophage-inflammator
154 Like hemopoietic cell homing, levels of stromal cell-derived factor-1 are high at sites of breas
157 ically associate and form a heterodimer upon stromal cell-derived factor-1 or CXCL12 (SDF-1) stimulat
158 ophic effects of mesenchymal stem cell (MSC) stromal cell-derived factor-1 release on the effects of
160 e of adhesion molecules, CXC receptor 4, and stromal cell-derived factor-1 signaling pathway in the r
161 ediated by E-selectin and can be enhanced by stromal cell-derived factor-1 under different wall shear
162 ue repair and suggest that overexpression of stromal cell-derived factor-1 via gene therapy is a stra
165 d CXCR4 (specific receptor for CXC chemokine stromal cell-derived factor-1) in CLL cells of a patient
166 n-1 receptor 2, programmed cell death-1, and stromal cell-derived factor-1) pathways, as was histolog
168 n-1 receptor 2, programmed cell death-1, and stromal cell-derived factor-1) with consequent myocardia
169 cent staining showed higher numbers of CD31+ stromal cell-derived factor-1+, chemokine receptor type
170 n CXCR4, which binds the chemokine CXCL12 or stromal cell-derived factor-1, a chemokine that has been
171 scular endothelial growth factor-A [VEGF-A], stromal cell-derived factor-1, and matrix metalloproteas
172 n expressions of mitochondrial cytochrome c, stromal cell-derived factor-1, C-X-C chemokine receptor
173 ein 7, macrophage colony-stimulating factor, stromal cell-derived factor-1, tissue inhibitor of metal
174 roblast growth factor, stem cell factor, and stromal cell-derived factor-1, whereas SVPs release high
175 cally augmented along with downregulation of stromal cell-derived factor-1-degrading enzyme dipeptidy
180 e chemokine (SLC)/CC ligand (CCL)21), CXCR4 (stromal cell-derived factor-1/CXCL12), and CXCR5 (B cell
181 in response to the chemokines MIP-3beta and stromal cell-derived factor-1; and 3) significantly incr
182 beta 1-integrin ligand fibronectin regulated stromal-cell derived factor-1 (SDF-1) activation of ERK.
183 ent evidence demonstrates that the chemokine stromal-cell derived factor-1 (SDF-1, also known as CXCL
185 11, leukemia inhibitory factor (LIF), gp130, stromal cell derived factor-1a (SDF-1a), and thrombopoie
186 MKP-1-null mice had higher levels of plasma stromal cell-derived factor-1a, which negatively correla
188 of vascular endothelial growth factor D and stromal cell-derived factor 1alpha (P = .037 and .025, r
191 CXCR4 is the receptor for the chemokine stromal cell-derived factor 1alpha (SDF-1alpha) and elic
192 tor for the normal physiological function of stromal cell-derived factor 1alpha (SDF-1alpha) and the
193 gration toward formyl-Met-Leu-Phe (fMLP) and stromal cell-derived factor 1alpha (SDF-1alpha) as well
194 s the ability to cleave the chemokine CXCL12/stromal cell-derived factor 1alpha (SDF-1alpha) at its p
195 droxypropyl-beta-cyclodextrin (BCD) inhibits stromal cell-derived factor 1alpha (SDF-1alpha) binding
197 inhibitors for monocyte migration induced by stromal cell-derived factor 1alpha (SDF-1alpha) or fMLP.
199 otent chemotactic responses to the chemokine stromal cell-derived factor 1alpha (SDF-1alpha), indicat
203 gulating secretion of the angiogenic factors stromal cell-derived factor 1alpha (SDF-1alpha)/CXCL12,
204 y, the migration of MKs toward a gradient of stromal cell-derived factor 1alpha (SDF1alpha) and the f
206 rts have identified a role for the chemokine stromal cell-derived factor 1alpha and its receptor CXC
208 eptor CXCR4 expressed by the CTL and CXCL12 (stromal cell-derived factor 1alpha) secreted by tumor ce
210 s involved in the signaling cascade of IL-2, stromal cell-derived factor 1alpha, and type I interfero
211 is induced by constitutively active Rac1 and stromal cell-derived factor 1alpha-induced ERM dephospho
214 ded EPCs underwent ex vivo modification with stromal cell-derived factor-1alpha (100 ng/mL) to potent
215 and signaling studies with the CXCR4 agonist stromal cell-derived factor-1alpha (chemokine (CXC motif
216 f trans-endothelial migration in response to stromal cell-derived factor-1alpha (CXC chemokine ligand
217 okine receptor CXCR4 and its cognate ligand, stromal cell-derived factor-1alpha (CXCL12), regulate ly
218 lly, exogenous administration of recombinant stromal cell-derived factor-1alpha (SDF) enhances neovas
219 is process, particularly when activated with stromal cell-derived factor-1alpha (SDF), known to be th
222 ignificantly reduce the extent of subsequent stromal cell-derived factor-1alpha (SDF-1alpha [CXCL12])
224 ction by examining chemotaxis in response to stromal cell-derived factor-1alpha (SDF-1alpha) as well
226 through the trophic effects of the chemokine stromal cell-derived factor-1alpha (SDF-1alpha) binding
227 rred after a necessary switch in bone marrow stromal cell-derived factor-1alpha (SDF-1alpha) expressi
229 ression of HIF-1alpha, CXCR4, and its ligand stromal cell-derived factor-1alpha (SDF-1alpha) in heman
233 To investigate the effects of the chemokine stromal cell-derived factor-1alpha (SDF-1alpha) on VLA-4
236 in diabetes is due to decreased wound level stromal cell-derived factor-1alpha (SDF-1alpha), a chemo
237 and plasma levels of its endogenous ligand, stromal cell-derived factor-1alpha (SDF-1alpha), correla
238 otein-coupled receptor for the ligand CXCL12/stromal cell-derived factor-1alpha (SDF-1alpha), plays a
241 ophage inflammatory protein II (vMIP-II) and stromal cell-derived factor-1alpha (SDF-1alpha), were sy
242 we show that the secreted signaling protein stromal cell-derived factor-1alpha (SDF-1alpha), which a
243 appeared additive and distinct from that of stromal cell-derived factor-1alpha (SDF-1alpha), which i
244 s secrete several chemo-cytokines, including stromal cell-derived factor-1alpha (SDF-1alpha), which t
245 Surprisingly, Cdc42 was dispensable for stromal cell-derived factor-1alpha (SDF-1alpha)- or B-ly
246 lls by expression of SPA1 or Rap1GAP blocked stromal cell-derived factor-1alpha (SDF-1alpha)-stimulat
251 the ligand for the CXCR4 chemokine receptor stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12),
252 stration of endothelial progenitor cells and stromal cell-derived factor-1alpha analog) could perform
253 and CSCs further enhanced the production of stromal cell-derived factor-1alpha and vascular endothel
254 neurotoxic natural ligands of CXCR4, such as stromal cell-derived factor-1alpha or viral macrophage i
255 (SMM)-chemokine analogs derived from natural stromal cell-derived factor-1alpha or viral macrophage i
258 rleukin-10, Tumor Necrosis Factor alpha, and stromal cell-derived factor-1alpha were reduced in the i
259 the cognate CXC chemokine receptor 4 ligand stromal cell-derived factor-1alpha were unchanged in bot
260 L5551 inhibited CXCR4 binding to its ligand, stromal cell-derived factor-1alpha, and reduced hypoxia-
261 roteinase (MMP) -2, soluble VEGF receptor 1, stromal cell-derived factor-1alpha, and soluble Tek/Tie2
262 d growth factor, epidermal growth factor, or stromal cell-derived factor-1alpha, but not basic fibrob
264 at, in contrast to the natural CXCR4 ligand, stromal cell-derived factor-1alpha, which promotes the e
266 ived factor-1alpha, and reduced hypoxia- and stromal cell-derived factor-1alpha-mediated migration do
269 CXCR4, a receptor for the chemokine CXCL12 (stromal-cell derived factor-1alpha), is a G-protein-coup
270 that the naturally occurring splice variant stromal cell-derived factor 1gamma/CXCL12gamma is the mo
271 hybrid screen that identified rhesus macaque stromal cell-derived factor 2-like protein 1 (SDF2L1), a
273 omal cell-derived factor 1-alpha (engineered stromal cell-derived factor analog [ESA]) induces contin
274 ic oxide bioavailability/cGMP in response to stromal cell-derived factor and resulted in a decrease i
276 steoglycin, epiregulin, proliferins 2 and 3, stromal cell-derived factor, and cathepsins B, F, and Z.
278 is largely governed by interactions between stromal cell-derived factor (SDF)-1 and CXC chemokine re
279 ered chemokine receptor CXCR7 and its ligand stromal cell-derived factor (SDF)-1 are known to be invo
280 aired mobilization was associated with lower stromal cell-derived factor (SDF)-1 expression levels in
281 esis that pancreatic tissue injury induces a stromal cell-derived factor (SDF)-1 gradient to chemoatt
285 ures based on the differential expression of stromal cell-derived factor (SDF)-1alpha and CXCR4 at th
286 creased vascular deposition of the chemokine stromal cell-derived factor (SDF)-1alpha and medial and
287 that ubiquitin and the cognate CXCR4 ligand stromal cell-derived factor (SDF)-1alpha do not share CX
289 runcated ubiquitin antagonizes ubiquitin and stromal cell-derived factor (SDF)-1alpha induced effects
290 y higher in AMI-SDB patients, whereas plasma stromal cell-derived factor (SDF)-1alpha levels were sig
291 f heme oxygenase (HO)-1 and the secretion of stromal cell-derived factor (SDF)-1alpha were upregulate
292 s binding activity was comparable to that of stromal cell-derived factor (SDF)-1alpha, the only natur
293 used to evaluate ATG-mediated inhibition of stromal cell-derived factor (SDF)-1alpha-driven Jurkat T
295 , interferon-induced protein (IP)-10/CXCL10, stromal cell-derived factor (SDF)-1alpha/CXCLl2, monocyt
296 ptor family of proteins, is the receptor for stromal cell-derived factor (SDF-1 alpha) and is a princ
298 -deficient T cells to the chemokines CXCL12 (stromal cell-derived factor [SDF]-1alpha) and CCL19 (mac
299 n the chemokine receptor CXCR4 is engaged by stromal cell-derived factor (SDF1)alpha, it triggers cel
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