ライフサイエンスコーパス: structural analyses

1 strate and cosubstrate sites, as revealed by structural analyses.

2 This was shown by chemical and structural analyses.

3 ptidoglycan pose a challenge to conventional structural analyses.

4 ing a direct binding assay, mutagenesis, and structural analyses.

5 l shift differences, thus paving the way for structural analyses.

6 6, within the FAK family is explained by our structural analyses.

7 ylotrophic yeast Pichia pastoris (PpCSP) for structural analyses.

8 structurally mapped after sequence and X-ray structural analyses.

9 cies would not have been predicted from past structural analyses.

10 hrough extensive kinetic, thermodynamic, and structural analyses.

11 r positive selection by various sequence and structural analyses.

12 been defined by mutational, biochemical and structural analyses.

13 bserved in DNA-zinc-finger interactions from structural analyses.

14 products is not amenable to high-resolution structural analyses.

15 eat family and has served as a prototype for structural analyses.

16 odies using alanine-scanning mutagenesis and structural analyses.

17 ronments and may be useful for other protein structural analyses.

18 atom of Gly48 of protease as examined in the structural analyses.

19 9- and K33-linked chains for biochemical and structural analyses.

20 hree main families based on evolutionary and structural analyses (A-, B- and C-families), with the B-

21 NMR and small-angle X-ray scattering (SAXS) structural analyses allowed us to construct models of bo

22 Our structural analyses also demonstrate that self-intoxicat

23 Based on the X-ray structural analyses, an earlier study has made a compell

24 seen for CsF and CsCl, single-crystal X-ray structural analyses and (1)H NMR spectroscopic studies r

25 Structural analyses and binding experiments comparing th

26 g of mouse brain tissue, and will facilitate structural analyses and connectomics of large assemblies

27 to serum C1q as judged from biochemical and structural analyses and exhibits the characteristic shap

28 Based on structural analyses and genetic and biochemical experime

29 Structural analyses and immunofluorescence of actin fila

30 around axons is currently widely studied by structural analyses and large-scale imaging techniques,

31 Structural analyses and molecular dynamics simulations s

32 insights that could prove helpful in further structural analyses and screening of ECA(LPS) among Ente

33 The combined computer-based structural analyses and supporting physicochemical prope

34 ecular Cell, Blacklow and colleagues use NMR structural analyses and the combination of deletion mapp

35 Structural analyses and theoretical calculations togethe

36 onents (including isomeric NAs) for in-depth structural analyses, and a method by which NA analytes,

37 ut not Galphaq, Using sequence conservation, structural analyses, and mutagenesis, we identify a hydr

38 preference of FadD10 through biological and structural analyses, and the data indicate long chain sa

39 troscopic titrations, ICP-MS, single-crystal structural analyses, and theoretical calculations.

40 Moreover, structural analyses are performed revealing relevant cha

41 we use a combination of VA RNAI mutagenesis, structural analyses, as well as PKR activity and binding

42 s the ability to gain access to a variety of structural analyses at one place and with a strong inter

43 Comparative structural analyses between iLOV and its progenitors rev

44 ze and electronic properties were chosen for structural analyses by MALDI-TOF, MALDI-FTICR, and DIOS-

45 Structural analyses by mass spectrometry allowed the ide

46 Evolutionary and protein structural analyses can provide functional insights into

47 Structural analyses combined with binding assays indicat

48 These clustering/structural analyses combined with modular computational

49 Careful structural analyses combined with other NAPRTase sequenc

50 n, this glycolipid was subjected to detailed structural analyses, combining gas-liquid chromatography

51 Structural analyses define the stoichiometry of the comp

52 Detailed structural analyses delineate the mechanism of quinone r

53 Biochemical and structural analyses demonstrate that Cmpd-43 and its clo

54 Recent biochemical, genetic and structural analyses demonstrate that GA de-represses its

55 Finally, structural analyses demonstrated CG17282 is a noncanonic

56 Structural analyses demonstrated that one antibody inter

57 However, biochemical and structural analyses demonstrated the apicomplexan orthol

58 Structural analyses demonstrated the profound influence

59 mbined with the accompanying biochemical and structural analyses directly correlate VP35 dsRNA bindin

60 Structural analyses further localize ORF19 and ORF32 pro

61 Structural analyses guided the discovery of a broad, spl

62 Our in vitro assembly and structural analyses have been enabled by the creation of

63 Previous genetic and structural analyses have determined that an Spx-binding

64 Furthermore, structural analyses have identified biochemically discre

65 Previous CaCC structural analyses have relied on homology modelling of

66 insolubility of e-gp41, most biophysical and structural analyses have relied on the production of tru

67 High-resolution crystal structural analyses have revealed that I-CLiPs harbor th

68 X-ray crystallographic structural analyses helped explain the enhanced folding

69 Our structural analyses highlight differences in the interac

70 as further investigated through the multiple structural analyses including HPLC, IR and NMR.

71 Biochemical and structural analyses indicate how plasticity of hydrophob

72 Structural analyses indicate that Ccp1 forms a homodimer

73 Spectroscopic and x-ray diffraction structural analyses indicate that despite their non-fibr

74 Structural analyses indicate that MFS transporters evolv

75 Our structural analyses indicate that the relative shape and

76 rchromicity, the circular dichroism, and the structural analyses indicated that Psi(39) enhanced the

77 omicity, circular dichroism ellipticity, and structural analyses indicated that the anticodon modific

78 Compositional and structural analyses indicated that this antifreeze conta

79 anced or force-independent in labeling, with structural analyses indicating the force-enhanced sites

80 These structural analyses led us to test the role of the poly-

81 Structural analyses localized the BH4 interaction site t

82 or binding to arabinoxylan, although protein structural analyses may be required to confirm some of t

83 A combination of measurements of pKa values, structural analyses of 2,6-diarylanilinium cations, and

84 Structural analyses of a mutant talin-H2418F at pH 6.0 a

85 Genetic, biochemical, and structural analyses of an Nbs1-Ctp1 complex show Nbs1 re

86 re-based vaccine design depends on extensive structural analyses of antigen-antibody complexes.Single

87 Structural analyses of APRs indicate that APRs are three

88 Recent structural analyses of ARFs and Aux/IAAs have raised que

89 nfirm the amino acid sequences and carry out structural analyses of both mature toxins using multiple

90 Here, we describe detailed functional and structural analyses of CCRs from Medicago truncatula and

91 Solution-state structural analyses of cyclopentyllithium and cyclopenty

92 Structural analyses of distinct segments ("protomers") o

93 ontents of every 3D structure, plus detailed structural analyses of each protein chain, DNA-RNA chain

94 Previous mutational and structural analyses of Encephalitozoon cuniculi Ecm1, a

95 Structural analyses of Fab fragments of mAbs 023.102 and

96 Structural analyses of features characteristic for parti

97 Using detailed structural analyses of FeRh films of varying crystalline

98 Here, we describe structural analyses of five different extensively retarg

99 The combined biochemical and structural analyses of FrbF provide insights into this p

100 Structural analyses of FtsN by nuclear magnetic resonanc

101 Previously, structural analyses of fully functional G alpha(12/13) s

102 Structural analyses of germline mAb BBE6.12H3 in an Ag-f

103 zed IRX8 and IRX9 and performed chemical and structural analyses of glucuronoxylan (GX) from irx8 and

104 rate previous physiological, biochemical and structural analyses of glutamate receptors and provide a

105 re investigated through single-crystal X-ray structural analyses of guest-exchanged 1S and 1R.

106 In this study, biochemical and structural analyses of H. pylori HypB (HpHypB) revealed

107 Structural analyses of helicases from this family indica

108 tools for detailed, high-throughput, de novo structural analyses of highly sulfated GAGs.

109 X-ray structural analyses of inhibitor-bound crystal structure

110 Structural analyses of KaiC crystals identify three pote

111 Secondary structural analyses of locus A recombinant WxL domain-co

112 oles are explained by recent biochemical and structural analyses of MAGUKs, which demonstrate their c

113 Structural analyses of membrane proteins reveal a large

114 Previous structural analyses of NRs, although productive in eluci

115 Recent advances in the biochemical and structural analyses of nucleic acid cytidine deaminases

116 Structural analyses of other cap-binding proteins indica

117 Here we describe an NMR-based strategy for structural analyses of potassium channel-ligand complexe

118 Kinetic, mutagenic, and structural analyses of PvADA and kinetic analysis of fiv

119 Structural analyses of ribosomal complexes indicate that

120 Structural analyses of S112A.3-Cl HOPDA and S112A.3,10-d

121 ts that the samples are amenable to detailed structural analyses of spherules engaged in RNA synthesi

122 Biochemical and structural analyses of sRNPs assembled with mutant sRNAs

123 Here we present functional and structural analyses of Stn1 and Ten1 from multiple buddi

124 especially if combined with high-resolution structural analyses of such inhibitors to shed light on

125 Structural analyses of the Abeta peptides showed that ap

126 Also, structural analyses of the altered proteins identified c

127 Structural analyses of the architecture of SSB and RPA s

128 Our detailed structural analyses of the ASPP-p53 interactions provide

129 Homology modeling and comparative structural analyses of the cAMP binding domains of Epac

130 comprehensive biochemical, biophysical, and structural analyses of the complex formed between PGC-1a

131 Structural analyses of the complexes with oxaloacetate a

132 We have carried out 3D structural analyses of the core editing complex or "L (l

133 Structural analyses of the E2 epitope bound to hu5B3.v3

134 tegrative approach of three-dimensional (3D) structural analyses of the entire phage by cryo-electron

135 Structural analyses of the extracellular region of stem

136 , we review recent genetic, biochemical, and structural analyses of the genes and proteins involved i

137 ost & Microbe, Moonens et al. (2016) perform structural analyses of the Helicobacter pylori adhesin B

138 it can serve as a starting point for further structural analyses of the HOPS tethering complex.

139 Kinetic and structural analyses of the inhibition by this and other

140 Based largely on structural analyses of the ligand binding domain of SdrG

141 Structural analyses of the LM and LAM variants produced

142 Here, we present biochemical and structural analyses of the MATH-BTB protein, SPOP.

143 I report that combining phylogenetic and structural analyses of the mitochondrial protein sequenc

144 y at a similar level to wild-type NFeoB, and structural analyses of the nucleotide-free and GDP-bound

145 lls in vitro In summary, our biochemical and structural analyses of the P. luminescens lectin PllA ha

146 PFam54 genes, we performed phylogenomic and structural analyses of the PFam54 gene array from ten B.

147 Structural analyses of the polysaccharide components, co

148 Structural analyses of the PRL-1.Peptide 1 complex revea

149 Structural analyses of the protein-tyrosine phosphatase

150 Structural analyses of the R57A/R96A and R57E/R96E doubl

151 Structural analyses of the receptor binding hemagglutini

152 Spectroscopic structural analyses of the S4-S5 linker supported this c

153 Thus, while structural analyses of the S510/D(b) complex provide a s

154 While the structural analyses of the signaling-active and -inactiv

155 Detailed energetic and structural analyses of the simulation results indicate t

156 Structural analyses of the subtype C protease bound to n

157 Through structural analyses of the T4 bacteriophage packaging mo

158 rch on transposable elements, no large-scale structural analyses of the TE proteome have been perform

159 We report the biochemical and structural analyses of the TE/CLC domain in polyketide s

160 The structural analyses of the three complexes using crystal

161 Prior PS structural analyses of the vaccine-associated serotype 2

162 In this study, we use biochemical and structural analyses of the Vav1 Ac and DH domains to exa

163 Based on the energetic and structural analyses of the wild-type and mutant enzymes,

164 Structural analyses of these revealed primarily an influ

165 However, only medium resolution structural analyses of this complex have been reported.

166 ir with cytosine, detailed thermodynamic and structural analyses of this modification have not been r

167 X-ray structural analyses of tridentate halogen bond donors (h

168 Structural analyses of tRNase Z(L) performed by limited

169 Structural analyses of Tse6 show that it resembles mono-

170 o fibril deposits might provide insight, but structural analyses of TTR from amyloid deposits have be

171 Primary sequence comparisons and x-ray structural analyses of two MERS-CoV 3CLpro and inhibitor

172 Here we present structural analyses of two rabbit MAbs, R56 and R20, aga

173 Detailed sequence and structural analyses of Ydr109c and FGGY as well as homol

174 Structural analyses of yeast and mammalian CTD are hampe

175 animal cells and is a strategy for focusing structural analyses on functionally important glycans.

176 Structural analyses on other riboswitch RNA classes, whi

177 In the present experiments, we focused our structural analyses on the ventral occipitotemporal regi

178 Structural analyses performed on adults showed that repr

179 Prior biochemical and structural analyses pinpointed the amidine moiety of bas

180 c studies, which, when combined with ongoing structural analyses, promise to provide details for mech

181 Traditional structural analyses provide a static image of conformers

182 Enzyme kinetic and NA structural analyses provide an explanation for the high

183 Our structural analyses provide pseudo-atomic models at vari

184 Biochemical and structural analyses provide unique insights into the sub

185 Secondary and tertiary structural analyses provided evidence to support the pre

186 l calculations, electrical measurements, and structural analyses provides evidence of room-temperatur

187 The enzymatic and structural analyses reported here provide a valuable mol

188 ular modeling and nuclear magnetic resonance structural analyses reveal direct hirsutinolide:Stat3 bi

189 Structural analyses reveal glycosaminoglycan binding sit

190 recognition mechanisms vary from RNA to RNA, structural analyses reveal recurring strategies that ari

191 Structural analyses reveal that both the enzyme and subs

192 Sequence and structural analyses reveal that DOHH belongs to a family

193 Phylogenomic and structural analyses reveal that F17-like pili are closel

194 Our structural analyses reveal that in contrast to the heter

195 The solid-state and computational structural analyses reveal that m-CBPQT(2(+*)) is ideall

196 Structural analyses reveal that m12 sequesters a large N

197 Whole genome structural analyses reveal that one of these kinases, IK

198 Structural analyses reveal that the differences in speci

199 g the tDED filament structure as a template, structural analyses reveal the interaction surfaces betw

200 Structural analyses reveal the mechanism of recognition

201 Precise X-ray structural analyses reveal the rather unexpected (electr

202 ther with results of genomic, proteomic, and structural analyses, reveal several putative virulence f

203 Structural analyses revealed an arc of nucleotides in 25

204 Biochemical and structural analyses revealed cleavage of ESF1 propeptide

205 Biofilm structural analyses revealed country-specific difference

206 Previous structural analyses revealed important differences betwe

207 Chromatin structural analyses revealed interactions within the car

208 Enzyme kinetics and structural analyses revealed SmCI to be an inhibitor of

209 Ultra-structural analyses revealed that desmosomes were absent

210 Structural analyses revealed that S-nitrosylated cystein

211 In silico sequence disorder and structural analyses revealed that SmeZ, unlike the three

212 The structural analyses revealed that steric force inherent

213 Structural analyses revealed that the AAVM41 capsid is a

214 Structural analyses revealed that the beta-hairpin of 40

215 T cell recognition foot-print and pMHC-I structural analyses revealed that the cross-reactive T c

216 Biochemical and structural analyses revealed that the DeltakasB mutant s

217 Structural analyses revealed that the RhoGAP domain of M

218 Extensive structural analyses revealed that this AAV-derived vecto

219 Recent structural analyses revealed the close proximity of Cys-

220 rved tertiary structure of these regulators, structural analyses revealed unexpected diversity in the

221 ere evidenced by morphological, physical and structural analyses, revealed elongated structures protr

222 se findings with solvent mapping and various structural analyses reveals alternative druggable sites

223 This finding, together with comparative structural analyses, reveals that the principal site of

224 Our structural analyses shed light on the genetic mutations

225 X-ray and computational structural analyses show a "transition-metal-like" cis-b

226 Sequence and structural analyses show that Anbu and BPH are both dist

227 Structural analyses show that eukaryotic SWEETs are comp

228 Sequence and structural analyses show that FREP family across 12 Dros

229 Structural analyses show that IMes-N2O is able to act as

230 Kinetic, biochemical, and X-ray structural analyses show that the two expressed proteins

231 Our previous structural analyses show that TlpB binds urea with high

232 Structural analyses showed an increase in polar side cha

233 The BA9/10 regions identified through structural analyses showed increases in blood oxygen lev

234 Ultra-structural analyses showed mitochondrial and endoplasmic

235 Sequential and structural analyses showed that residues conserved throu

236 X-ray and NMR structural analyses showed that the (S)-C5'-Me epimers a

237 Structural analyses showed that the extract contained tw

238 Structural analyses showed that the M159D/E mutations ha

239 Mutagenesis and structural analyses showed that the Mms21-Smc5 interface

240 Structural analyses showed that the polysaccharide porti

241 Previous structural analyses showing little differences between n

242 ERG results are consistent with the structural analyses showing the greatest attenuation of

243 Structural analyses, site-directed mutagenesis experimen

244 Most structural analyses so far have targeted the purified ro

245 l-based interferon suppression assays, these structural analyses strongly support a unified model of

246 Based on these structural analyses, substrate-based aldehyde inhibitors

247 sis have relied upon either very generalized structural analyses such as circular dichroism or the cr

248 Structural analyses suggest a face-to-face stacking of D

249 for sCJD(MM1) prions by more than 100 days; structural analyses suggest a profound change in the ori

250 Our structural analyses suggest a specific protein-RNA displ

251 Both biochemical and X-ray crystal structural analyses suggest an unusual mechanism of beta

252 Further structural analyses suggest that all CNTN ectodomains ad

253 he function of LGI proteins remains unknown, structural analyses suggest that LGI1 could be either lo

254 Comparative structural analyses suggest that major leaps in protein

255 Structural analyses suggest that S305-P forms a charge-l

256 Structural analyses suggest that the major capsid protei

257 Our structural analyses suggest that these connections to th

258 D, and V321I residue changes were found, and structural analyses suggest that these mutations distort

259 DZ2 mediates the GRASP self-interaction, and structural analyses suggest that this occurs via a uniqu

260 Our structural analyses suggest that YfiT might function as

261 Further bioinformatics, biochemical, and structural analyses suggested that phenylalanine (F309)

262 Structural analyses suggested that the mutation disturbs

263 Finally, structural analyses support findings of previously misse

264 These kinetic measurements, and supporting structural analyses, support a mechanism in which some u

265 for s-ShhNp formation, and provide the first structural analyses supporting the existence of Shh mult

266 Evidence from in vitro and structural analyses supports a critical role for Cited2

267 ith supporting biochemical data and previous structural analyses, supports the notion that this is th

268 se rPrP aggregates more amenable to detailed structural analyses than bona fide PrP(Sc).

269 h genetic complementation and polysaccharide structural analyses that C. glabrata ANP1, MNN2, and MNN

270 a coli to demonstrate through mutational and structural analyses that variant glycan structures can b

271 square deviations combined with the detailed structural analyses, the helical bundle of the CB(1) rec

272 lation signature that couples epigenomic and structural analyses, thereby offering insights into the

273 f A. baumannii LPS were limited primarily to structural analyses; therefore, studies evaluating the c

274 However, structural analyses to date have focused on how SF1A hel

275 Here we use functional and structural analyses to demonstrate that HLA-C expression

276 Here, we use comprehensive biochemical and structural analyses to demonstrate that PTPRG.CNTN3-6 co

277 elationships requires sensitive and accurate structural analyses to determine parameters like degree

278 ns using the cell culture infectious HCV and structural analyses to identify mechanisms of HCV resist

279 We have now used comparative sequence and structural analyses to study the structure and evolution

280 andom forest predictor trained on rule-based structural analyses together with structural clustering

281 In the structural analyses, Tp-THF of GRL-015, -085, and -097 s

282 The chemical and structural analyses using HRTEM, Rutherford backscatteri

283 Biochemical and structural analyses using NMR and fluorescence spectrosc

284 Based on our sequence and structural analyses using the crystal structure of CA_C2

285 Through detailed biochemical and structural analyses, we demonstrate that both mouse and

286 Through a combination of biochemical and structural analyses, we demonstrate that SRC1-4 is the m

287 nation of molecular dynamics simulations and structural analyses, we find that the neck sequentially

288 - and nuclear magnetic resonance (NMR)-based structural analyses, we identified a phosphorylated O-ma

289 ults presented here, and previously reported structural analyses, we present a catalytic mechanism in

290 On the basis of these kinetic and structural analyses, we propose possible mechanistic rol

291 Based on structural analyses, we propose that the enhanced rate o

292 Using cellular, biophysical, and structural analyses, we show that CDR3alpha residues can

293 erium exchange, fluorescence anisotropy, and structural analyses, we show that the flexibility of the

294 Based on these kinetic, biochemical, and structural analyses, we suggest that these compounds are

295 Whole-brain structural analyses were also performed.

296 Additional spectroscopic and structural analyses were done to track the dependencies

297 ize exclusion chromatography using FPLC, and structural analyses were performed by electrospray ioniz

298 omprehensive bioinformatics, biochemical and structural analyses were used to acquire a better unders

299 Here we combine structural analyses with a "Reconstructed Evolutionary A

300 By combining a series of structural analyses with functional testing, we show tha