ライフサイエンスコーパス: structural difference

1 that reported for HlgAB, but with important structural differences.

2 r flap structure-selective nucleases despite structural differences.

3 and mammalian CTDs, which is consistent with structural differences.

4 for isomeric carbohydrates with even subtle structural differences.

5 h can serve as an alternative or additive to structural differences.

6 rated independent of biochemical and spindle structural differences.

7 ding hypomethylated regions show substantial structural differences.

8 rthologs is predicted to manifest as notable structural differences.

9 ion of an extra inertial term accounting for structural differences.

10 usually analyzed in 3D for interpretation of structural differences.

11 the larger conformer suggesting considerable structural differences.

12 ed into eight families based on sequence and structural differences.

13 the bovine enzyme, indicating that inherent structural differences affect ligand access in these enz

14 Do structural differences alone affect the level of air pol

15 le focuses on the pore region, reviewing how structural differences among glutamate receptor subtypes

16 which is astonishingly long, given that the structural differences among the filter conformations ar

17 that observed with cholesterol, although the structural differences among them are subtle.

18 d coils in solution, there exist significant structural differences among them at shorter timescales.

19 entity threshold, performs analysis of their structural differences and clusters them according to th

20 stigate the relationship between age-related structural differences and visual evoked field (VEF) and

21 equal clustering we study and quantify their structural differences, and using SIS (Susceptible-Infec

22 However, these structural differences appear subtle in comparison with

23 These minor structural differences are also likely to underlie CYP51

24 2D NMR spectroscopic data suggest that structural differences are associated with different cys

25 med by micro-CT of human lung specimens that structural differences are associated with unique S(fSAD

26 Structural differences are defined using X-ray absorptio

27 Remarkably, we find that these structural differences are largely controlled by only tw

28 mouse and Syrian hamster and show that their structural differences are mainly governed by two residu

29 In comparison to the unmodified trimer, structural differences are observed at the interface bet

30 Two main structural differences are observed in that the N-termin

31 remains unclear whether all of the observed structural differences are part of the allosteric mechan

32 cides with a region of the active site where structural differences are seen between tankyrases and o

33 Major structural differences are seen between the full-length

34 otocol offers unique opportunities to detect structural differences arising from various experimental

35 the samples was primarily explained by block structural differences as determined by HPSEC-PAD.

36 lts are consistent with a model in which the structural differences associated with the direction of

37 l three enzymes were solved, revealing major structural differences at the N-terminal domain and dime

38 bria between two sub-states exhibiting small structural differences at the terminal methine bridges A

39 These results suggest a potential structural difference between active and inactive networ

40 ncy with autoimmune aHUS could be due to the structural difference between CFHR1 and the autoantigeni

41 In this study we present an alternative structural difference between cyano- and iodocuprates, w

42 charide composition analysis showed no major structural difference between heparan sulfate from contr

43 y of prothrombin in solution and the drastic structural difference between its alternative conformati

44 gical and biochemical results concerning the structural difference between membrane glycoproteins of

45 Our results indicate that a subtle structural difference between paradox inducers and break

46 This structural difference between the bacterial and host cel

47 Specifically, our study revealed a structural difference between the cell envelopes of L. i

48 One key structural difference between the NOS isoforms is the am

49 g chemical probing analysis, we identified a structural difference between the two 5'UTRs in the high

50 The structural difference between the two hexasaccharides wa

51 monomeric AgamOBP47 revealed that the major structural difference between the two Plus-C proteins lo

52 our data provide important insight into the structural difference between the two proteins that may

53 ts a posttranslational modification and/or a structural difference between the two proteins.

54 The minimal primary structural difference between variants was a single amin

55 these structures to understand the inherent structural differences between a and d sites to clarify

56 The most prominent structural differences between Abeta(1-42) oligomers and

57 om the extracellular space to lysosomes, and structural differences between AGs alter the efficiency

58 ay of (14)N and (35)Cl spectra, reveal clear structural differences between all compounds.

59 Despite evolutionary and structural differences between alpha-carboxysomes and be

60 erent samples correlate directly to periodic structural differences between alpha-helical and beta-sh

61 ible evolutionary histories that explain the structural differences between any two genomes can be sa

62 We conclude that despite major structural differences between ATP synthase dimers of ci

63 Based on the structural differences between AVP and AVP-pVIc, we pres

64 The data reveal (1) significant structural differences between B. napus and pea root cap

65 The structural differences between bacterial and human prima

66 Subtle structural differences between BCoV and MHV NTDs, primar

67 We show significant structural differences between beta1 and beta3 TM/CT in

68 These results highlight fundamental structural differences between BK and Kv channels in the

69 We propose that the structural differences between bound and unbound forms a

70 Therefore, in the absence of significant structural differences between Co(2+)(2)-HAI and Mn(2+)(

71 Structural differences between delipidated and nondelipi

72 There are structural differences between Der f 1 and Der p 1 that

73 ence context of 3' splice sites and to small structural differences between drugs.

74 Structural differences between EF1143 apo and holo forms

75 agnetic resonance imaging was used to detect structural differences between groups.

76 esonance spectroscopy was used to reveal the structural differences between H69 with (PsiPsiPsi) and

77 trasaccharide and by taking into account the structural differences between HA, poly-GlcUA, and poly-

78 These data suggest that the structural differences between high- and low-SR synapses

79 d proteolytic digestion experiments revealed structural differences between HSSTnT isoforms and HCTnT

80 rm significant and consistent functional and structural differences between hub proteins that are co-

81 In contrast, structural differences between human and shark antibody

82 is due to changes in AKAP12 localization vs. structural differences between its two variants.

83 isting quantitative model fully explains how structural differences between kinesins alter kinetic ra

84 ces, expression of inflammatory markers, and structural differences between mature hemostatic and gro

85 The large structural differences between MCC and PCC also have gen

86 dan, whose emission spectrum is sensitive to structural differences between micellar and lamellar agg

87 sequence conservation, there are significant structural differences between microtubules assembled in

88 ing the sensitivity of NEXAFS to the extreme structural differences between model beta-sheets and alp

89 Structural differences between monomeric and dimeric vMI

90 ond-long atomistic simulations elucidate key structural differences between monomeric ApoE3 and ApoE4

91 edictive of the outcome in humans, given the structural differences between murine and human activati

92 To explore the hypothesis that structural differences between NaB and VPA account for t

93 The image results from OCT showed structural differences between normal and cancerous tiss

94 The structural differences between oxidized and reduced NQO2

95 To better understand the structural differences between P450s 3A4 and 3A5, the st

96 d within each design without any significant structural differences between phases.

97 Structural differences between prokaryotic UGM and AfUGM

98 heterologous ligands from other species, the structural differences between Qa-1(b) and HLA-E manifes

99 Furthermore, the demonstration that the structural differences between readily degradable and un

100 on is not a general phenomenon of LGICs, and structural differences between receptors may account for

101 There are several intriguing structural differences between resolvase and RuvC, and a

102 on by cryoEM has opened the door to defining structural differences between ribosomes of pathogenic o

103 Our results reveal structural differences between several triphosphate and

104 Here, we report the first study of the structural differences between Sindbis viruses grown in

105 ke previous hypotheses, we found significant structural differences between SPLUNC1 and BPI.

106 uggest that there are subtle but significant structural differences between T/F and chronic clade B E

107 These results suggest important structural differences between the accessibility of O(2)

108 The structural differences between the alphaI and betaA of t

109 Although structural differences between the analogues are minimal

110 he canonical maize isoform and with possible structural differences between the apomictic and sexual

111 (2+) permeability of NMDA receptors, and the structural differences between the closed and open state

112 This leads to structural differences between the complexes, particular

113 Given that the structural differences between the conductive and inacti

114 These mechanisms involve decreasing structural differences between the effector bound and un

115 Structural differences between the highly conserved link

116 n, using Phi-value analysis we show that the structural differences between the hot and cold denature

117 Calculations reveal that the structural differences between the I- and B-forms (the f

118 The polymorphism of HET-s parallels the structural differences between the infectious brain-deri

119 To date, possible structural differences between the intron RNP in its pre

120 The structural differences between the inward-facing YfkE an

121 ional structural ensembles, we show that the structural differences between the labeled and unlabeled

122 Although the structural differences between the occluded substrate bi

123 However, we also noted large structural differences between the orthologues from thes

124 This work reveals long-sought structural differences between the pre-accommodation of

125 The structural differences between the reported fullerenes w

126 These structural differences between the RRMs were reinforced

127 ify RNA ligands (aptamers) that could detect structural differences between the secretomes of pancrea

128 This difference is interpreted in terms of structural differences between the synthetic and natural

129 To detect in vivo structural differences between the two disorders, diffus

130 y analyses reveal that there are fundamental structural differences between the two enzymes, and NfnI

131 Structural differences between the two forms are compare

132 hetic mechanisms responsible for most of the structural differences between the two metabolites.

133 The structural differences between the two nanosheet assembl

134 ions within the DMS cell, linked back to the structural differences between the two protonated forms.

135 connected the binding scaffolds, suggesting structural differences between the various dimer subtype

136 Here, we map the structural differences between the yeast homologue of m-

137 Structural differences between the Zn1-DNA and Zn2-DNA c

138 Elucidating the structural differences between their closed and open sta

139 h forms have an alpha + beta fold; the major structural differences between them lie in the beta-shee

140 Galphai1:Ric-8A complex and the magnitude of structural differences between them.

141 tion of the A-tract arrays while maintaining structural differences between them.

142 ansition is surprising in light of the large structural differences between these polymorphs.

143 ange and site-directed mutations, we suggest structural differences between these two isoforms that a

144 ivity and resolution for detecting localized structural differences between two or more biological pr

145 ate the capsid determinants of this process, structural differences between wild-type (wt) AAV2 and a

146 of the chromosome is not likely to be due to structural differences between X chromosomes of European

147 oscopy to gain atomic level insight into the structural differences between Y145Stop prion protein am

148 Our studies demonstrate structural differences between yeast and mammalian micro

149 Despite this structural difference, both two and three disulfide-bond

150 To help explain how these small structural differences can have such a large effect, we

151 ains how the S components with large overall structural differences can interact with the same ECF mo

152 We present evidence that despite structural differences, carbamazepine and glibenclamide

153 We now report structural differences caused by amino acid substitution

154 ae ACE proteins (AnoACE2 and AnoACE3) reveal structural differences compared to human ACE, suggesting

155 s from mice lacking PRMT8 have no detectable structural differences compared with controls; however,

156 odels for the two species according to their structural difference complemented by numerical simulati

157 uctures confirmed the degree to which subtle structural differences could be determined using this me

158 These structural differences could provide insight into their

159 The structural differences detected by subtomogram analysis

160 Furthermore, we find that this structural difference dictates the rate at which the TNR

161 Slit guidance cue are imparted by intrinsic structural differences encoded in the extracellular Ig d

162 functional analysis are consistent with the structural differences evident in the x-ray atomic struc

163 The structural differences exhibited by 3A4 and 3A5 suggest

164 onal levels, it has become clear that subtle structural differences exist between the two sides and t

165 Only minor structural differences exist between the W972A RING doma

166 Significant structural differences exist in the overall fold of MAL

167 The results reported here reveal a clear structural difference for the bound DNA in solution vers

168 s; however, we observe small but significant structural differences for the 1095 procapsid compared t

169 The structural differences found at both Xyn10C-XBD domains

170 hGALT reveals significant structural differences from bacterial GALT homologues in

171 timely in the human olfactory system, whose structural differences from nonprimate macrosmatic speci

172 E. coli ZapA was determined, identifying key structural differences from the existing ZapA structure

173 This is surprising, given that structural differences generally reflect functional diff

174 ely related molecules distinguished by small structural differences, giving rise to individual molecu

175 individuals with type 1 diabetes, and these structural differences have been associated with neuroco

176 s in the solid state by introducing a unique structural difference, i.e., an oxovanadium(IV) in a squ

177 We speculate that the distinctive structural difference in the bound complexes of apoCaM-N

178 There was no significant structural difference in the fungal communities between

179 antibiotics) but not to tedizolid because of structural differences in A-ring C5 substituents between

180 Interestingly, despite structural differences in acyl chain composition between

181 uired resistance are attributable in part to structural differences in binding subsites, receptor sub

182 We aimed to investigate whether there are structural differences in children and adults with ADHD

183 Factors, including structural differences in chromanol head and isoprenoid

184 PCE is associated with structural differences in cortical and limbic regions.

185 their unaffected relatives, show widespread structural differences in corticostriatal and limbic net

186 We provide evidence to suggest that structural differences in DsbB oxidases (LpDsbB1 and LpD

187 generation (SHG) imaging microscopy to probe structural differences in fibrillar models of the ovaria

188 Ligand-binding induced structural differences in HER were determined to be loca

189 nd local shape analyses were used to measure structural differences in hippocampi between genotype gr

190 ty for PS(-) lipids, they induce substantial structural differences in lipid bilayers containing each

191 This study investigated structural differences in primary visual cortex between

192 se a pH-sensitive loop of FcRn, and identify structural differences in proximity to these hot spot re

193 Poverty is tied to structural differences in several areas of the brain ass

194 rences in the NAc and provides evidence that structural differences in synaptic connectivity and glut

195 ve quaternary structures differ markedly and structural differences in the active site explain the ob

196 Significant structural differences in the active site region are app

197 Structural differences in the active site region of GCC

198 from MERS-CoV and other human CoVs revealed structural differences in the alpha1 helix alters how th

199 trigger a renewed impetus for investigating structural differences in the amygdala, its genetic dete

200 To compare structural differences in the anterior chamber angle (AC

201 These functional differences were due to structural differences in the BC loop of the IgV domain

202 has been used over the past decade to study structural differences in the brains of children with au

203 f their daily experiences and that there are structural differences in the brains of these subjects c

204 w inferences between age- and gender-related structural differences in the cingulate gyrus and corres

205 n crystallized in lipidic cubic phase (LCP), structural differences in the Cmpd-1-bound A2AR-BRIL pre

206 A global search for structural differences in the Drosophila brain identifie

207 subsets of neuraminidase as a consequence of structural differences in the enzyme active site between

208 ere consistent with known nucleotide-induced structural differences in the Fe protein and indicated t

209 y) but differing in their membrane mobility (structural differences in the lipophilic tail).

210 Guided by structural differences in the loop region between beta4

211 e TcpB TIR domain, which reveals significant structural differences in the loop regions compared with

212 arainfluenza virus 5 (PIV5) F, with the main structural differences in the membrane distal apical loo

213 These structural differences in the Ndc80 complex between diff

214 es in the amygdala bilaterally (but not with structural differences in the Nucleus Accumbens).

215 gly, this structure also reveals significant structural differences in the p35 subunit and p35/p40 in

216 Despite structural differences in the peripheral regions, the SA

217 in translation/accumulation and reverse the structural differences in the Pr loop were found in the

218 genetic variation in DLG4 is associated with structural differences in the preterm infant brain.

219 f 16S rRNA compared to WT ribosomes revealed structural differences in the region of helix 1.

220 (1.6 A C-alpha root mean square deviation), structural differences in the vicinity of Cys(101) disfa

221 We review and compare the structural differences in the vicinity of the active sit

222 and the diphosphate-specific OprO pores show structural differences in their binding sites situated i

223 rse enzymatic reactions, probably related to structural differences in their respective FAH domains;

224 In conclusion, even small structural differences in these beta-sulfonamide Asp ana

225 om Streptomyces roseosporus, but has notable structural differences in three amino acid residues and

226 yme formation and demonstrate that there are structural differences in unbound PP1 regulators that ha

227 Pediatric anxiety was associated with structural differences in vmPFC and hippocampus, regions

228 in ASD may reflect myelination and/or other structural differences including differences in axonal d

229 se proximity to bound analytes so that small structural differences induce distinct (19)F NMR shifts

230 crystalline variants enabled us to identify structural differences induced by the single amino acid

231 These structural differences involve sequences from both the N

232 The structural difference is located within the cytoplasmic

233 nd restriction enzymes demonstrated that the structural difference is the result of changes in the ph

234 The functional significance of these structural differences is underscored by decreased funct

235 The structural differences likely affect how Mre11 from diff

236 The structural differences mandate partitioning of sex and a

237 Local structural differences may account for the different sta

238 Considering that their structural differences may affect their physical and oxi

239 These structural differences may have an impact on the nature

240 These density and structural differences may underlie the increased suscep

241 biological activities, in spite of discrete structural differences, may reveal the existence of hydr

242 After adjusting for case-mix and hospital structural differences, model intraclass correlation ind

243 rther from the acceptor, consistent with the structural differences observed in duplex DNA where it h

244 Structural differences observed in two pseudopolymorphs

245 The structural differences observed were specific to the CA

246 Ca(2+)-dependent structural differences occur in the fourth EF-hand (EF4)

247 thick filament formation, and highlight the structural differences occurring between the coiled-coil

248 The structural difference of the Pd ensembles has a signific

249 lated mitochondrial network, whereas neither structural difference of the peroxisome network, nor alt

250 Moreover, it has been determined that the structural differences of immobilized antibodies (fragme

251 ution mass spectrometry was used to describe structural differences of NKR-P1A receptor.

252 d algorithm that quantitatively computes the structural differences of the three-dimensional networks

253 Despite these structural differences, OkrAI recognizes the DNA in a re

254 The two tri-DPP molecules with only a structural difference on alkyl substitutions, when blend

255 We investigated consequences of structural differences on resting-state functional conne

256 In order to investigate the impact of structural differences on tetramer stability, we measure

257 d-free nanobody-receptor interaction reveals structural differences on the cytoplasmic receptor side

258 -coordinate Fe(II) forms, revealing striking structural differences on the heme-proximal side of the

259 rystallographic studies revealed significant structural differences, particularly in the loop regions

260 structure upon RAG/HMGB1 binding and reveal structural differences, particularly near the heptamer,

261 knot region, and helical spine show distinct structural differences potentially important to signalin

262 isoforms vary in toxicity in accordance with structural differences, primarily in the number and patt

263 ed enzymes offer opportunities to reveal how structural differences produce different catalytic activ

264 ence similarity, BioY and ThiT display large structural differences (rmsd = 5.1 A), but the divergenc

265 between multiple biogenic amines with remote structural differences six carbon atoms away from the bi

266 soil gammaproteobacteria suggest that these structural differences stem from evolutionary pressure t

267 Minor structural differences such as relative carbon-carbon do

268 However, there are a number of significant structural differences, such as rearrangements in a trip

269 s and C-CRDs of MsaFBP32 exhibit significant structural differences, suggesting that they recognize d

270 This structural difference suggests that the beta-hairpin bea

271 loop and an adjacent area, which is the key structural difference that occurs upon activation.

272 atus PSII and spinach PSII, minor electronic structural differences that affect the manganese K-edge

273 t required for polymer export and has unique structural differences that allow the N-terminal deacety

274 of their CAPTR product ions, even for subtle structural differences that are not apparent from ion mo

275 gamma subunit working as a ratchet but with structural differences that make it a unique control mec

276 s (in the absence of concomitant gray matter structural differences) that predict processing speed.

277 Searching for structural differences, the crystal structure of Fe-SODA

278 pression levels, and (2) despite fundamental structural differences, the mechanisms mediating DNA acc

279 id A structures and the contribution of each structural difference to the ability of lipid A to activ

280 laining kinesin processivity and for mapping structural differences to functional differences in dive

281 s of Bcr-Abl p210, which constitute the only structural differences to p190.

282 the past 25 million years, despite its major structural differences to the human MSY.

283 ternary complexes in a similar manner, their structural differences together with differences in the

284 These structural differences, together with our molecular dyna

285 Moreover, no structural difference was detected between the phosphate

286 Baseline and longitudinal structural differences were compared using voxel-based m

287 Muscle structural differences were confirmed by histological an

288 A total of 13 compounds with a variety of structural differences were evaluated for topological ch

289 Complementary structural differences were identified in ventromedial p

290 r to that of HLA-E, significant sequence and structural differences were observed between the respect

291 Striking structural differences were observed for both aromatic a

292 No structural differences were observed in anterior segment

293 Moreover, these structural differences were observed solely in the right

294 nservation of structure, combined with their structural differences when compared with mammalian suga

295 ity properties in gastric fluid due to their structural differences which may explain their different

296 are not truly bulk-like, due to their subtle structural differences with the bulk.

297 PdxK in complex with ATP revealed important structural differences with the human enzyme.

298 cial enzyme in dTTP homeostasis and identify structural differences within the active site that could

299 These findings suggest that there are structural differences within the optic nerve complex be

300 t cognate conformations of receptors display structural differences within their binding site where b