ライフサイエンスコーパス: structural fluctuation

1 -induced increase in the amplitudes of local structural fluctuations.

2 identical properties and exhibit independent structural fluctuations.

3 structures involved or the magnitude of the structural fluctuations.

4 ive to the ever-present background of faster structural fluctuations.

5 ation selectivity, while revealing localized structural fluctuations.

6 y proteins, such as enzymes, is modulated by structural fluctuations.

7 re controlled by temperature dependent local structural fluctuations and crystal fluidity.

8 holipid bilayers under osmotic stress allows structural fluctuations and deformation of membranes to

9 bond in the portal region, thereby arresting structural fluctuations and effectively locking the liga

10 ocess model, consisting of EX2-limited local structural fluctuations and EX1-limited global unfolding

11 ntaining the G:A mismatch showed much larger structural fluctuations and failed to adopt a well-defin

12 vide insights into the nature of large-scale structural fluctuations and flexibility of the nucleosom

13 ile Red is shown to be a useful probe of the structural fluctuations and heterogeneity of these membr

14 paration of allosteric motion into intrinsic structural fluctuations and ligand-induced contributions

15 Structural fluctuations and molecular excitations of hyd

16 solvent model reproduced the average protein structural fluctuations and sample conformations similar

17 unfolding in equilibrium, graded increase in structural fluctuations and temperature-dependent swelli

18 esults were also used to analyze the peptide structural fluctuations and the free-energy surface of h

19 The spatial extent of structural fluctuations appears highly dependent on both

20 ed, but as a result of allosteric effect the structural fluctuations are altered significantly, which

21 supporting early claims that its equilibrium structural fluctuations are larger than those of the WT

22 at the reorientation of SeCN(-) and the RTIL structural fluctuations are substantially slower in the

23 Localized structural fluctuations are the primary physical origin

24 We found that dynamics (structural fluctuations) are essential in explaining oxi

25 whole cells at 0 degrees C but with sizable structural fluctuations associated with local mobility.

26 pores with dimethylformamide (DMF) slows the structural fluctuations by reducing the ability of the M

27 in decreased folding free energy and larger structural fluctuations compared with those of wild-type

28 estigation examines whether and how specific structural fluctuations contribute to desolvation of the

29 The simulations reveal significant structural fluctuations corresponding to lateral opening

30 of the initial diffusional encounter and of structural fluctuations determine the overall rate of th

31 pairs in DNA that become open as a result of structural fluctuations, DNA bending, or protein-DNA int

32 e analysis were used to infer that intrinsic structural fluctuations dominate LID motion, whereas lig

33 r every intermediate in the catalytic cycle; structural fluctuations efficiently channel the enzyme t

34 We suggest that these structural fluctuations expose a nucleation point for ps

35 tend to be disulfide-insecure, in that their structural fluctuations expose their disulfide bonds in

36 Many proteins rely on rare structural fluctuations for their function, whereby solv

37 to approximately 100 ps) protein equilibrium structural fluctuations have not been characterized expe

38 MOF in low concentration, revealed that the structural fluctuations have time constants of 7 and 670

39 w fragment) and LdG-DNA duplex elucidate the structural fluctuations imparted by the LdG lesion, as w

40 To study the role of structural fluctuation in fine-tuning DNA affinity, we p

41 idin is achieved mainly through constraining structural fluctuations in F-actin and suggests that fac

42 se A, and discuss its application to probing structural fluctuations in folded proteins.

43 Analysis of structural fluctuations in the bound and unbound states

44 me, and emphasizes the necessity for dynamic structural fluctuations in the catalytic mechanism of sm

45 en structure of SAHH lead to the presence of structural fluctuations in the direction of the open-to-

46 roach for imaging the changes of statistical structural fluctuations in the first stage of myelin deg

47 of its allosteric transition, accompanied by structural fluctuations in the heme pocket of the beta-c

48 These observations suggest that the slower structural fluctuations in the hydrophobic core, indicat

49 rovide further characterization of the large structural fluctuations in the native states of proteins

50 cted accessibility to oxygen indicating that structural fluctuations in the protein provide intermole

51 g intensities are consistent with a model of structural fluctuations in which secondary structures un

52 to provide ultrafast snapshots of molecular structural fluctuations, in analogy with multidimensiona

53 in with those of its modified forms revealed structural fluctuations induced by post-translational mo

54 However, the nanoscale structural fluctuations intrinsic to these superlattices

55 Its origin lies in the strong structural fluctuations introduced by the spatially exte

56 We thus propose that matching of structural fluctuations is a component of how TCRs scan

57 lthough a native-like structure is retained, structural fluctuations lead to attenuation of selected

58 w that these modifications promote or dampen structural fluctuations, likely through competing effect

59 t the allosteric effector-induced quaternary structural fluctuation may contribute to the reduced lig

60 mparisons for COX-1 versus COX-2 active site structural fluctuations may also provide useful informat

61 Although structural fluctuations may be expected to have an impor

62 Thus, tailored orbital symmetry and structural fluctuations may be used to produce coherent

63 ng, multistep ordered assembly pathways, and structural fluctuations occurring within fully assembled

64 Structural fluctuations of a protein are essential for a

65 clear plasticity, correlated spatio-temporal structural fluctuations of chromatin in undifferentiated

66 On the other hand, structural fluctuations of DNA give rise to steric colli

67 provides detailed information regarding the structural fluctuations of lipid bilayers, including bot

68 f solids, we demonstrate a common scaling of structural fluctuations of lysozyme protein embedded in

69 e-shaping techniques can probe the ultrafast structural fluctuations of MOFs.

70 the 2D-IR results demonstrate that the fast structural fluctuations of Ngb are significantly slower

71 d for the conformational entropy provided by structural fluctuations of proteins exists, beyond which

72 The local structural fluctuations of SAHH are analyzed by performi

73 By systematically comparing the structural fluctuations of the capsid protein, a strong

74 ared to a 15 ns simulation of apo-mAChE, the structural fluctuations of the enzyme are substantially

75 mputer simulations show that restricting the structural fluctuations of the h4 helix is key to rigidi

76 plete orientational randomization of CO2 and structural fluctuations of the IL (spectral diffusion) i

77 intramolecular disulfide bond places on the structural fluctuations of the protein neuroglobin (Ngb)

78 sity to applied field, laser wavelength, and structural fluctuations of the QD.

79 Structural fluctuations of these ionic clusters result i

80 re also used to assess the spatial extent of structural fluctuations of various hemoglobins in soluti

81 The effects of structural fluctuations on charge transfer in double-str

82 ne the amplitudes and time scales of protein structural fluctuations on fast time scales.

83 Some key regions of the protein feature structural fluctuations on nanosecond time scales, which

84 egments in oriented specimens, and measuring structural fluctuations on the microsecond time scale.

85 Relaxation measurements on NRho reveal structural fluctuations on the microseconds-milliseconds

86 phatidylcholine binding drives unanticipated structural fluctuations outside of the canonical activat

87 Proteins exhibit structural fluctuations over decades of time scales.

88 ctron-proton transfer processes, where local structural fluctuations play a pivotal role.

89 d to be disulfide-secure, meaning that their structural fluctuations preferentially expose their thio

90 Structural fluctuations promoted by these defective moti

91 subunit in the tetramer, but the associated structural fluctuations propagate across the entire beta

92 These results indicate that structural fluctuations rather than the time-averaged st

93 at the selectivity filter, thus resulting in structural fluctuations, reduced K(+) affinity, and incr

94 periodically the molecule exhibits dramatic structural fluctuations represented by the opening and c

95 Analysis of such structural fluctuations reveals the local mechanical pro

96 Detailed analysis of the structural fluctuations shows that the stability differe

97 hat deoxy-Hb A exhibits substantially larger structural fluctuations than HbCO A.

98 titute the thermodynamic epiphenomena of the structural fluctuation that accompanies ligand-receptor

99 eric sites play a pivotal role in activating structural fluctuations that allosterically modulate fun

100 at the characteristics of the native protein structural fluctuations that cause proton nuclear spin-l

101 ion, are admissible and result in only minor structural fluctuations that do not affect overall compl

102 is accompanied by a substantial reduction of structural fluctuations that dominate in the apo structu

103 ron spin-echo spectroscopy was used to study structural fluctuations that occur in hemoglobin (Hb) an

104 Identification and characterization of structural fluctuations that occur under native conditio

105 d binding can modulate the extent of protein structural fluctuations that transiently disrupt hydroge

106 nd intrinsically on both molecular shape and structural fluctuations, thereby providing the enticing

107 es within this key region, we decrease local structural fluctuations to slow ataxin-3 aggregation.

108 ed by large energetic barriers that minimize structural fluctuations under physiological temperatures

109 has been typically assumed, but experiences structural fluctuations upon binding ligands.

110 ime of 2.1 mus), the relaxation time of tRNA structural fluctuations was determined to be approximate

111 g into consideration geometrical factors and structural fluctuations, we show that ions tend to be bo

112 celle, the cytoplasmic helices undergo large structural fluctuations, whereas the transmembrane pore

113 ion in the portal region arrests large-scale structural fluctuations, which are required for retinoic

114 ar exist where function can be correlated to structural fluctuations with known magnitude and timesca

115 We report the direct observation of structural fluctuations within a single nanocrystal usin