ライフサイエンスコーパス: structural protein

1 titis virus glycoprotein (VSV G) as the only structural protein.

2 in films composed of reflectin, a cephalopod structural protein.

3 cer-promoter interactions do not employ this structural protein.

4 ized by an interaction with a scaffolding or structural protein.

5 erves as anti-oxidative enzyme but also as a structural protein.

6 rate, or the molecular interactions of viral structural proteins.

7 dramatic conformational changes within viral structural proteins.

8 saging the tc-VLPs on cells expressing CCHFV structural proteins.

9 neration genetically engineered self-healing structural proteins.

10 (VLVs) that contain VSV G but no other viral structural proteins.

11 transcription factors are regulated by these structural proteins.

12 alpains, and proteolytic breakdown of muscle structural proteins.

13 rus containing the chikungunya virus (CHIKV) structural proteins.

14 cleavable element between the capsid and PE2 structural proteins.

15 flagellin or type 3 secretion system (T3SS) structural proteins.

16 es and extensions contained all of the viral structural proteins.

17 ficant fraction of the response specific for structural proteins.

18 ATA4, TBX5, MEF2C) transcription factors and structural proteins.

19 , in agreement with biological uses of these structural proteins.

20 viral DNA replication and synthesis of viral structural proteins.

21 ntal phage proteomics to identify 83% of the structural proteins.

22 can be tolerated at the cleaved ends of non-structural proteins.

23 is confirmed downregulation of metabolic and structural proteins.

24 d in series through a network of elastic and structural proteins.

25 pressing premembrane and envelope Zika virus structural proteins.

26 t of five conserved genes that encode virion structural proteins.

27 ly composed of spidroins, a unique family of structural proteins.

28 Non-structural protein 1 (NS1) facilitates flavivirus acquis

29 GNS1) and to favor specific detection of non-structural protein 1 (NS1) of dengue fever.

30 An immunosensor for the non-structural protein 1 (NS1) of the dengue virus based on

31 ce (RNAi) suppressor activity of the IAV non-structural protein 1 (NS1), reported over a decade ago(2

32 Influenza B virus encodes non-structural protein 1 (NS1B) that binds human ISG15 and p

33 se polyproteins at three sites releasing non-structural protein 1 (nsp1), nsp2, and nsp3.

34 atial relationships between nsP3 and the non-structural protein 1 (nsP1).

35 , a C terminally extended version of its non-structural protein 1, the expression of which enhances n

36 predominantly comprised of a BTV-encoded non-structural protein 2 (NS2).

37 Chikungunya virus (CHIKV) non-structural protein 2 (nsP2) is a multifunctional protein

38 ough DiCoMPS, the synthesis of the viral non-structural protein 3 (NS3), which is enriched in the AUA

39 Non-structural protein 3 (nsp3) is the largest nsp in the co

40 The non-structural protein 3 (nsP3) plays essential roles during

41 ncodes the conserved macro domain within non-structural protein 3.

42 The dengue virus (DENV) non-structural protein 5 (NS5) comprises an N-terminal methy

43 DENV non-structural protein 5 (NS5) contains enzymatic activities

44 The non-structural protein 5A (NS5A) is a hepatitis C virus (HCV

45 HCV non-structural protein 5A (NS5A) is a multifunctional protei

46 The hepatitis C virus (HCV) non-structural protein 5B (NS5B) is an RNA-dependent RNA pol

47 Non-structural protein 5B (NS5B) is the RNA-dependent RNA po

48 ow collagen, the most abundant extracellular structural protein, alters its organization during fibro

49 restriction modification enzymes, and virion structural proteins, although the specific traits and se

50 Our results suggest conservation of structural proteins among tailed phages and add to the g

51 ticle composed of multiple copies of a major structural protein, an RNA-dependent RNA polymerase, a h

52 in the 0 and +1 frames to produce the viral structural proteins and a +1 overlapping open reading fr

53 s require dynamic interactions between viral structural proteins and a variety of cellular factors.

54 ds, which are assembled from seven different structural proteins and composed of several core protein

55 the premature expression of critical muscle structural proteins and formation of enlarged thickened

56 lso be directly crosslinked to several large structural proteins and nucleoside triphosphatases.

57 lor ISM was shown on cytoskeletal-associated structural proteins and on 3D four-color images includin

58 s integrity by controlling the expression of structural proteins and protecting Sertoli cells from ea

59 diseases, and yet most of their genes encode structural proteins and proteins involved in their repli

60 By screening the three structural proteins and seven nonstructural proteins pre

61 oth of which require the concerted action of structural proteins and sortases for their polymerizatio

62 ly encoded as a single operon expressing the structural proteins and the encapsulated enzymes of the

63 suggest a tight interdependency between Gag structural proteins and the protease during the developm

64 tails concerted interactions among the viral structural proteins and the RNA genome.

65 JE patients were mostly CD4(+) and targeted structural proteins and the secreted protein NS1.

66 f different salts (NaCl, KCl and MgSO(4)) on structural proteins and their hydration in muscle tissue

67 T cells that recognize epitopes in the viral structural proteins and thus can provide direct help to

68 The Gag protein is the main retroviral structural protein, and its expression alone is usually

69 cates its genome, expresses all of the viral structural proteins, and releases viral particles at lev

70 rotein, intracellular/extracellular enzymes, structural proteins, anti-stress/anti-disease protein, e

71 -density lipoproteins (HDLs) and their major structural protein, apolipoprotein A1 (apoA1), recovered

72 that CideB specifically interacts with VLDL structural protein, apolipoprotein B100 (apoB100), but n

73 ontrast to primary DENV2 infection, in which structural proteins are a minor component of the respons

74 e.g., secretory tissues, tissues abundant in structural proteins) are also tissues in which gene expr

75 gene encoding filaggrin (FLG), an epidermal structural protein, are the strongest risk factor identi

76 structure also contains the viral DNA and a structural protein as a scaffold.

77 d concentration of individual regulatory and structural proteins as filopodia elongate and subsequent

78 These viruses encode conserved replicase and structural proteins as well as more diverse accessory pr

79 leton contains an assemblage of adhesion and structural proteins as well as two highly acidic protein

80 he i-motif nanowire shares similarities with structural proteins, as far as its tensile stiffness, bu

81 The structural proteins assemble the needle apparatus, which

82 ng the potential risk of ADE associated with structural protein-based ZIKV vaccines.

83 est candidate for the role of a nucleocapsid structural protein because it is abundant, it is localiz

84 ha in regulating the morphology of the T-bar structural protein BRP (Bruchpilot).

85 he viral genome and the genes encoding viral structural proteins, by binding to and oligomerizing on

86 hanics as regulated by stress on the nuclear structural proteins called lamins, which are examined in

87 llular localization of caveolae and caveolar structural proteins CAV-1 and Cavin-1 and that these def

88 The MutaBind server maps mutations on a structural protein complex, calculates the associated ch

89 We found that caveolin-1, a structural protein component of caveolar membranes, is a

90 Until now, the identity of the main structural protein components of the basal layer was unk

91 vergencies in drug specificity of homologous structural proteins contribute to the variation of WhiB7

92 uctural proteins NS3 and NS5A as well as HCV structural proteins core and E2 in Huh7.5 cells.

93 In the insect cuticle, structural proteins (CPs) and the polysaccharide chitin

94 The VP40 matrix protein is a key structural protein critical for Ebola virus budding.

95 We examined the roles of two chromatin structural proteins, Ctcf (CCCTC-binding factor) and Hmg

96 dy, we generated a uniquely stabilized plant structural protein (cysteine [Cys]-oleosin) that encapsu

97 nfection-related proteins, including several structural proteins derived from the liver extracellular

98 Our findings indicate that structural proteins destined for the ciliary axoneme are

99 us-like particles (VLPs), comprised of viral structural proteins devoid of genetic material, are tuna

100 into the individual functions of a viral non-structural protein during infection with a medically imp

101 the relative expression of structural to non-structural proteins during different phases of the viral

102 dictated the production of a discrete set of structural proteins during infection of a cell: capsid,

103 DMD patients lack the expression of the structural protein dystrophin caused by mutations within

104 y (DMD) is caused by absence of the integral structural protein, dystrophin, which renders muscle fib

105 Finally, we discovered that ZIKV structural proteins (E, prM, and C) are major targets of

106 that FLIm parameters linked to the amount of structural proteins (e.g. collagen, elastin) and lipids

107 IgG avidity, and IgG response to the 3 viral structural proteins (E1, E2, and C), reflected by immuno

108 a putative fusion peptide (FP) in the major structural protein E2 of classical swine fever virus (CS

109 system with new properties by combining two structural protein elements.

110 pool of billions of molecules - metabolites, structural proteins, enzymes, oligonucleotides - multi-s

111 2), and a fragment of the type III secretion structural protein EscC (pVAX-56.2), was able to induce

112 knockdown of RPLP1/2 reduced levels of DENV structural proteins expressed from an exogenous transgen

113 loss and reduced lipid synthesis enzyme and structural protein expression up to 96 hours postburn.

114 owever, TMPRSS2 overexpression decreased MHV structural protein expression, release of infectious par

115 ucleotide-dependent processes, expression of structural proteins, fatty acid and lipid metabolism in

116 y coordinated molecular system involving the structural protein filaggrin (FLG).

117 ings underscore the importance of retroviral structural proteins for integration site selection and t

118 Viral structural proteins form the critical intermediary betwe

119 ound to be remarkably stiff, similar only to structural proteins forming viral shell, silk, or collag

120 order caused by the absence of dystrophin, a structural protein found on the cytoplasmic surface of t

121 Shank3 is a structural protein found predominantly at the postsynapt

122 Collagens are an important family of structural proteins found in the extracellular matrix wi

123 t cell culture-derived HCV (HCVcc) harboring structural proteins from a diverse array of HCV genotype

124 The finding suggests that recombinant structural proteins from heterologous expression have po

125 Structural proteins from naturally occurring materials a

126 In contrast to enzymes, viral structural protein function can be much more challenging

127 amma-Catenin (Plakoglobin), a well-described structural protein functioning at the adherens junctions

128 ging is mediated by interactions between the structural protein Gag and elements near the 5' end of t

129 ct with the nucleocapsid domain of the viral structural protein Gag and is incorporated in significan

130 The prototype foamy virus (PFV) structural protein GAG associates with chromosomes via a

131 The retroviral structural protein Gag binds to the inner leaflet of the

132 otably, our previous study showed that HIV-1 structural protein Gag colocalizes with a group of uropo

133 PM association of the main structural protein Gag depends on its myristoylated MA d

134 interaction of the viral RNA genome with the structural protein Gag facilitates virion assembly and p

135 The retroviral structural protein Gag has three major domains.

136 to virions, and RNA interacts with the viral structural protein Gag in the cytoplasm.

137 However, the structural protein Gag is the only component required fo

138 We previously showed that the HIV-1 structural protein Gag localizes to the uropod, a rear-e

139 bserved as its colocalization with the viral structural protein Gag or its accumulation in virus part

140 Binding of the retroviral structural protein Gag to the cellular plasma membrane i

141 The correct ratio of the HIV-1 structural protein Gag to the envelope protein (Env) is

142 comitant with recruitment of the major HIV-1 structural protein Gag to the site of cell-cell contact.

143 embly, determined by the localization of the structural protein Gag, vary in a cell-type-dependent ma

144 fied to express SHIV89.6P genes encoding the structural proteins Gag and Env.

145 first spacer peptide (SP1) of the precursor structural protein, Gag.

146 cently, frameshift mutations in the caveolar structural protein gene Caveolin-1 (CAV-1) were identifi

147 Even deletions of one of the known structural protein genes that is present in all known fu

148 d transcription-associated genes and several structural protein genes.

149 , at 24 h postsurgery the mRNA expression of structural proteins (GFAP and AQP4) was compromised.

150 The Golgi structural protein GM130 is responsible for connecting d

151 m of gp175 is active and cleaves purified IB structural proteins gp93 and gp89.

152 s in the antibody responses to specific PEDV structural proteins have important implications in the d

153 Many globular and structural proteins have repetitions in their sequences

154 Structural protein homology to well-characterized phages

155 nant polypeptides derived from the four PEDV structural proteins, i.e., spike (S), nucleocapsid (N),

156 e six RNA segments encoding the prototypical structural proteins identified in other quaranjaviruses,

157 nse supports a central role for this nuclear structural protein in cellular homeostasis.

158 Here, we show that actin, the most abundant structural protein in eukaryotes, binds the LL-37 host d

159 d with apolipoprotein A-I (apoA-I), the main structural protein in HDLs.

160 In vivo, collagen I, the major structural protein in human body, is found assembled int

161 P. destructans, and that collagen, the major structural protein in mammals, is actively degraded by t

162 P30 plays an integral role as a cross-linked structural protein in the formation of lightweight rigid

163 ased tension biosensor for nesprin-2G, a key structural protein in the LINC complex, which physically

164 Filaggrin is a major structural protein in the stratum corneum of the epiderm

165 the ribosome and drives translation of viral structural proteins in a factor-independent manner.

166 nome-length chimeric HCV RNAs encoding GBV-B structural proteins in place of equivalent HCV sequences

167 e arrangement of collagen, elastin and other structural proteins in space and time embodies our tissu

168 amin B1 (LMNB1) constitutes one of the major structural proteins in the lamina mesh.

169 The levels of some key structural proteins in the nucleus, cytoskeleton, or ext

170 The progressive breakdown of structural proteins, in particular, medial elastin, is r

171 t intrinsic defects in the expression of key structural proteins including cytokeratin-10 and loricri

172 omains of gE/gI promote the sorting of viral structural proteins into proximal axons to begin axonal

173 er, the results suggest that Sfp1 is a major structural protein involved in footprint cohesion and po

174 ading frames in common that appear to encode structural proteins involved in interaction with the hos

175 stood collection of Ca(2)(+) homeostatic and structural proteins, ion channels, and enzymes.

176 plasma membrane (PM) association of the Gag structural protein is a critical step in viral assembly,

177 For retroviruses, the Gag structural protein is the primary driver of virus partic

178 does not suppress the expression of HIV non-structural proteins, it has been proposed that a constit

179 The human papillomavirus (HPV) major structural protein L1 composes capsomers that are linked

180 The vaccinia virion structural protein L4 stands out as the best candidate f

181 uric syndromes resulting from defects in GBM structural proteins (laminin beta2 or collagen alpha3 IV

182 changes are highly diverse, with examples in structural protein levels, the DNA repair machinery, and

183 nregulating expression of multiple epidermal structural proteins, lipid synthetic enzymes, and antimi

184 pping, we found that polymorphisms in JHM.WU structural protein M and nonstructural replicase protein

185 ral entry but rather on a combination of the structural protein M and nonstructural replicase-associa

186 We hypothesized that HIV structural proteins may contribute to lymphomagenesis di

187 Together, these findings reveal that nuclear structural proteins may exert bimodal transcriptional ef

188 found that two fragments of the myofibrillar structural protein myomesin-3 (MYOM3) are abnormally pre

189 he threshold for loss of solubility, and the structural proteins, myosin and actin, lost their native

190 potent newly identified inhibitors were KSHV structural proteins, namely ORF22 (glycoprotein H), ORF2

191 We present immunohistochemical data of structural proteins (NF200, Ankyrin G, and Myelin) and i

192 this phage encodes an entirely unique set of structural proteins not found in any currently known pha

193 The viral non-structural protein NS1, rather than a viral surface prot

194 The DENV non-structural protein NS4B and subgenomic flavivirus RNA in

195 ng three novel HCV DNA vaccines encoding non-structural proteins NS4B, NS5A and NS5B, we assessed the

196 that TRIM14 interacted with HCV encoded non-structural protein NS5A and could strongly induce its de

197 re we find a new interaction between the non-structural protein NS5A and DGAT1 and show that the traf

198 se in part through the expression of its non-structural protein (nsp) 1, which inhibits both host gen

199 en its antibody response in three common non-structural protein (NSP) ELISAs and its age.

200 Coronavirus (SARS-CoV) is composed of 16 non-structural proteins (nsp1-16) encoded by ORF1a/1b.

201 ow that binding of the rotavirus-encoded non-structural protein NSP2 to viral ssRNAs results in the r

202 y, for the first time, suggests that the non-structural protein NSs of CCHFV, a member of the genus N

203 nce depends on the interferon antagonist non-structural protein (NSs), which remains poorly character

204 the cleavage of type II collagen, the major structural protein of articular cartilage.

205 Polymerization of fibrin, the primary structural protein of blood clots and thrombi, occurs th

206 Mutations in collagen II, a main structural protein of cartilage, are associated with var

207 Here, we report that cavin-1, a structural protein of caveolae, modulates the oncogenic

208 Caveolin-1 is an essential structural protein of caveolae, specialized plasma membr

209 colocalized with caveolin-1 (Cav-1), the key structural protein of caveolae.

210 e alpha3 chain of laminin 332 (LAMalpha3), a structural protein of epidermal/epithelial basement memb

211 research into the Gag polyprotein, the main structural protein of HIV-1 and all other retroviruses,

212 ession is inhibited by apolipoprotein B, the structural protein of low-density lipoprotein, which bin

213 The major structural protein of MLV particles, Gag, frequently co-

214 Single-particle imaging showed that DRC4, a structural protein of the axoneme, moves in association

215 Caveolin-1 (CAV-1), a structural protein of the cell membrane, is involved in

216 ratory show that the ExsY protein is a major structural protein of the exosporium basal layer of B. c

217 rthermore, we demonstrated that VP7, a major structural protein of the inner core, is not required fo

218 ther, we demonstrate for the first time that structural proteins of KSHV can counteract p53-induced a

219 Virions composed of the structural proteins of one flavivirus and the genomic RN

220 subgenomic RNA could readily be packaged by structural proteins of the DENV2 strain 16681, productio

221 are characterised by autoantibodies against structural proteins of the dermal-epidermal junction and

222 Keratin K2 is one of the most abundant structural proteins of the epidermis; however, its biolo

223 lex pathways that often converge on the main structural proteins of the nucleus, the lamins.

224 ly discriminated from aliphatic lipids, from structural proteins of the tissue matrix and from other

225 esence of MoRF regions in structural and non-structural proteins of Zika virus using an aforementione

226 ed by a layer of phospholipids and the small structural protein oleosin.

227 Mice expressing HCV structural proteins on a background of reduced expressio

228 mbers of the order Nidovirales express their structural protein ORFs from a nested set of 3' subgenom

229 reassemble the key proteolytic product, the structural protein p24 (CA), into a distinct, mature hex

230 , further highlighting the paradigm of viral structural proteins playing additional functional roles

231 lls (hASCs) by knocking down 2 primary cilia structural proteins, polycystin-1 and intraflagellar pro

232 Here, we show that if a given structural protein positively regulates its own gene exp

233 VP24 protein, a structural protein present in all family members, blocks

234 (viral RNA, certain replicases, and certain structural proteins) present in/on the intercellular nan

235 Our designed sequences are based on a structural protein produced in squid suction cups that h

236 n natural systems, directed self-assembly of structural proteins produces complex, hierarchical mater

237 educed lipid synthesis enzyme expression and structural protein production up to 96 hours postburn.

238 Structural protein:protein interaction studies reveal th

239 indings reveal distinct roles for Zap70 as a structural protein regulating integrin-mediated control

240 sign and structure-property relationships of structural proteins remains unclear.

241 Junctophilin-2 (JP2) is a structural protein responsible for jSR/T-tubule docking.

242 l analysis also revealed the presence of HCV structural proteins, RNA, and apolipoproteins in the Gol

243 ococcus-expressed pili are composed of three structural proteins: RrgB, which forms the polymerized b

244 of selective protein complexes with the key structural protein SAP97, which tightly regulates the sy

245 mplex entity containing a large portfolio of structural proteins, signaling molecules, and proteases.

246 2p/Snf2p, interacts with the heterochromatin structural protein Sir3p.

247 ne from both nonstructural protein (nsP) and structural protein (sP) open reading frames (ORFs).

248 esidues absent from previous biochemical and structural protein studies.

249 le molecules such as enzymes, but also large structural proteins such as collagens.

250 in AD is caused by phosphorylation of Golgi structural proteins, such as GRASP65, which is induced b

251 mediated by changes to higher-order nuclear structural proteins, such as LaminB1.

252 ence for adaptive evolution, particularly of structural proteins, suggesting that most viral lineages

253 mutations did not affect RNA replication or structural protein synthesis but had deleterious effects

254 onal protein modifications, and their target structural protein TCHH are all involved in hair shaft f

255 While cytoskeletal structural proteins tended to differ seasonally, i.e., b

256 kerin modules to repeated cohesin modules of structural proteins termed scaffoldins.

257 replication capacity driven by Gag, a major structural protein that is a significant determinant of

258 s appears to be the first example of a viral structural protein that is also involved in the transcri

259 The VP40 matrix protein is a key viral structural protein that is critical for virion egress.

260 These data show that ATF5 is an essential structural protein that is required for the interaction

261 encode the nucleocapsid (N) protein, a major structural protein that plays multiple roles in the viru

262 ciated vertical filaments, are the essential structural proteins that anchor and organize both types

263 d characterize neutralizing epitopes on DENV structural proteins that can serve to inform vaccine str

264 Cytoskeletons are cell structural proteins that closely relate to migration, an

265 Structural proteins that connect the cell to its niche,

266 PH1 functions as a hub linking key motor and structural proteins that contain intrinsically disordere

267 D88-dependent abnormalities in expression of structural proteins that contribute to skin barrier func

268 ammals, prohibitins (PHBs) are considered as structural proteins that form a scaffold-like structure

269 eads to an organization of the rubella virus structural proteins that is different from that of alpha

270 Neurofilaments (Nf) are major structural proteins that occur exclusively in neurons.

271 llular matrix (ECM) is a complex assembly of structural proteins that provides physical support and b

272 ge of proteins, including motor proteins and structural proteins, that are known to transmit mechanic

273 factors regulate the expression of the lens structural proteins, the crystallins.

274 , solute transport, signal transduction, and structural proteins, the hypothesis naturally arises tha

275 ClO2 inactivates MS2 by degrading its structural proteins, thereby disrupting the ability of M

276 e oxidizing capsular protein thiols and as a structural protein, tightly controlled expression of fun

277 ed to truncating mutations in the sarcomeric structural protein titin (TTNtv).

278 s viral RNA, certain replicases, and certain structural proteins to neighboring cells.

279 is accuracy, we uncover interactions between structural proteins, transcription factors, epigenetic m

280 Proteomics identified structural protein vimentin as an additional VEGF-HO-1 t

281 ed the role of a specific determinant in the structural protein VP1-2 in herpesvirus entry.

282 e evidence that the Norwalk virus (NV) minor structural protein VP2 is present in infectious virions,

283 Previous results indicated that the minor structural proteins, VP2 and VP3, might act as membrane

284 onstructural proteins (NSPs) 2, 5, and 6 and structural proteins (VPs) 1, 2, 3, and 6.

285 involving nonstructural proteins (NSPs) and structural proteins (VPs).

286 virions with DENV2 strain New Guinea C (NGC) structural proteins was not possible, despite the very h

287 r prediction of disease-causing mutations of structural proteins, we present a gene- and disease-spec

288 tability and steady-state levels of two T4SS structural proteins were affected by a homolog of tail-s

289 The genes coding for structural proteins were more permissive to mutations.

290 Differences in K(pw) between the structural proteins were relatively large (<2 log units)

291 mained unaffected, whereas the levels of PSI structural proteins were severely diminished, indicating

292 The Gag structural proteins were the most abundant viral protein

293 fic deletion of CTCF (a ubiquitous chromatin structural protein) were generated to explore the role o

294 ] CHK-152 and CHK-166) against the E2 and E1 structural proteins, which had therapeutic efficacy in i

295 ins as well as an assemblage of adhesion and structural proteins, which together, create a framework

296 ssortants contained heterologous VP2 and VP5 structural proteins, while only 17% had homologous VP2 a

297 d blood - with a focus on a few key abundant structural proteins whose expression dynamics have been

298 Here, we focus on RbmA, a structural protein with an unknown fold.

299 ced viral assembly and induced clustering of structural proteins with non-structural HCV proteins, in

300 secretion by sequestering effectors and some structural proteins within the bacterial cytoplasm.