ライフサイエンスコーパス: structure

1 all, periodic decreases in the overall noise structure.

2 ses a conformational shift to a less compact structure.

3 rticles without modification of the chemical structure.

4 esolution, providing the first bacterial FNO structure.

5 s mis-paired with cytosines on the pre-miRNA structure.

6 ontrast, frequency, congruency, and temporal structure.

7 rds accurate prediction of the full tertiary structure.

8 meters influence the resolution of a cryo-EM structure.

9 o permanent voids or channels in its crystal structure.

10 nges in the composition of nascent chromatin structure.

11 ic and ecological variation influence social structure.

12 ic character without decomposing or changing structure.

13 atic in vivo investigations of cell membrane structure.

14 es apply with equal validity to any cortical structure.

15 NM that does not have a parallel in-register structure.

16 es can drive adaptation and shape population structure.

17 phy as a pipeline for obtaining the required structures.

18 ellular behaviours to dismantle the aberrant structures.

19 gene product can self-assemble into amyloid structures.

20 ptimizing visualization of small subcortical structures.

21 f sequence 3' of such 'slippage-stimulatory' structures.

22 fabrication of emergent materials and their structures.

23 A121 can serve as a model for their tertiary structures.

24 tivity varies during the formation of phrase structures.

25 w synthetic biology tools to program spatial structures.

26 ailable data and understanding of ecological structures.

27 Fermi surface of lithium in several relevant structures.

28 plume particles and seafloor massive sulfide structures.

29 urs the generation of highly curved membrane structures.

30 ively to monosolvated-dimer-based transition structures.

31 og caused alterations in slit-diaphragm-like structures.

32 on of spatially-irregular and friable tissue structures.

33 egies based on more stable and more specific structures.

34 ion and quantification of complex biological structures.

35 xtract these biologically important acoustic structures.

36 e diatomic ligands for conceivable H-cluster structures.

37 -oxyl aromatic rings in the transition state structures.

38 A three-dimensional structure (3D) model of Ss-RIOK-2 was generated using th

39 um RIOK-2 protein kinase (Ct-RIOK-2) crystal structure 4GYG as a template.

40 iodistribution determination, a PET-specific structure-activity relationship (SAR) effort, and specif

41 Initial structure-activity relationship studies have resulted in

42 Our initial structure-activity relationship studies on 7-methoxy-4-m

43 The provided insights and framework for structure-activity relationships of bivalent degraders a

44 This study expands the structure-activity relationships on our original series

45 ansfer and in situ production of HO(*) using structure-activity relationships.

46 k provides key details into how an EV71 IRES structure adapts to hijack a cellular protein, and it su

47 cles and extensively sprout into gray matter structures after SCI; therefore, it has been proposed th

48 h prior knowledge of the canonical secondary structure, allow accurate inference of non-canonical pai

49 ails of promoter recognition by sigma(N) The structure allowed us to build and refine an improved sig

50 Notably, in one structure, an ordered water molecule with a high GIST di

51 StrAuto implements a pipeline that combines STRUCTURE analysis with the Evanno Delta K analysis and

52 research areas of RNA biology including RNA structure analysis, RNA alignment, RNA annotation, RNA-p

53 ranslational modifications in regulating the structure and aggregation of Httex1 and suggest that its

54 Furthermore, the structure and bonding of compound 1 has been investigate

55 onship between eukaryotic plankton community structure and carbon export potential at the Western Ant

56 ncident X-ray diffraction to observe crystal structure and chemical transition of perovskites.

57 se and its metabolites disturbed the spindle structure and chromosomal alignment, which was associate

58 d provides exquisite detail about myocardial structure and composition, abnormalities of which form t

59 rdered proteins (IDPs) that lack a unique 3D structure and comprise a large fraction of the human pro

60 ch enables the simultaneous determination of structure and dynamics of conformationally heterogeneous

61 In this work we study the structure and energetics of triple junctions in graphene

62 of nicotinic acetylcholine receptor (nAChR) structure and function and have potential as nervous sys

63 of loss of P2X7 receptor function on retinal structure and function during aging.

64 To study changes in both retinal structure and function during the first month following

65 le we provide a comprehensive picture of SBT structure and function in plants.

66 ked protein conjugates without affecting the structure and function of biologically relevant proteins

67 k shows that zygosity can help us relate the structure and function of gene regulatory networks.

68 efined by 10-year change in left ventricular structure and function.

69 ation mechanisms, with the resulting amyloid structure and functionality.

70 We describe the structure and morphology of aggregates formed by the P23

71 ulation in meningococci, their transcriptome structure and output of regulatory small RNAs (sRNAs) ar

72 he variants on the three-dimensional protein structure and performed subcellular localization studies

73 samples of ST12-Ge were synthesized, and the structure and purity were verified using powder X-ray di

74 on characterization of the three-dimensional structure and receptor specificity of the H15 hemaggluti

75 We describe herein its structure and replicative cycle, along with genomic anal

76 exes is discussed in relation to the overall structure and the charge density profile of the two biop

77 Both the high-temperature average crystal structure and the low-temperature incommensurately modul

78 complexes varied dramatically with the guest structure and were correlated with the thermodynamic bin

79 methods were then used to explore solvation structures and electronic couplings.

80 Here, we report that certain RNA template structures and G-rich sequences, ahead of diverse revers

81 vents them from assembling into hierarchical structures and leads to the formation of discrete nickel

82 tive conformations, taking into account more structures and measurements than any previous classifica

83 Due to their unique structures and multifunctionalities, two-dimensional (2D

84 This demonstrates a means of tuning the structures and properties of high-entropy alloys in a ma

85 orce behind the creation of new prochlorosin structures and represents an intriguing mechanism by whi

86 previous descriptions of their heterogeneous structures and spatial distributions in rodents and prim

87 The cage structures and UV/Vis spectra were independently confirm

88 s to explain the causes of protein sequence, structure, and function.

89 in the understanding of proteasome assembly, structure, and function.

90 The single crystals of tetragonal structure are easy to cleave into perfect square-shaped

91 theory, numerical estimates for real protein structures are currently lacking.

92 us of Alberta, which preserves integumentary structures as organic layers, including continuous field

93 primate superior colliculus (SC), a midbrain structure associated with attention and gaze, while monk

94 rly understood experiments in gated graphene structures at low doping.Two-dimensional Dirac semimetal

95 Previously we developed a structure-based method for prediction of transcription f

96 Structure-based vaccine design depends on extensive stru

97 orogens provide an easy way to create porous structures, but their usage is limited due to synthetic

98 r matrix (ECM), remodeling ECM fiber network structure by condensing, degrading, and aligning these f

99 to variation in multilayer contact networks structured by sex in a population of European badgers Me

100 trical transport measurements and electronic structure calculations, we demonstrate that the intercal

101 hole wavefunction overlaps in the AlN/GaN DA structure can be remarkably enhanced up to 97% showing t

102 not project to the brainstem, but brainstem structures can influence this nucleus.

103 hese modifications and a dynamic view of RNA structure changes with increased numbers of 2-5-linkages

104 reveals a key role for cryptic diversity in structuring communities of mutualists.

105 evelops, an additional commensurate magnetic structure consistent with Gamma3 irreducible representat

106 tiation and exhibited patterns of population structure consistent with local adaptation.

107 t programs, knowledge of flavivirus particle structure, definition of E dimers as the key antigenic t

108 Their sheet-like structure derives from two independent polymeric network

109 atalysts is challenging and entails material structure design and tailoring across a range of length

110 X-ray crystallography allows macromolecular structure determination at both X-ray free electron lase

111 n of specimen preparation methods, assisting structure determination to high resolution with minimal

112 kes progress on the detailed study of satDNA structure difficult.

113 in fine pores of coal matrix, the nano-pore structure directly influences gas storage and transport

114 Our results reveal that tuning the interface structure, distribution, and phase stability to simultan

115 and the lanthionine synthetase suggests that structure diversification, rather than structure refinem

116 lays an essential role in determining capsid structure during the self-assembly of CCMV-like particle

117 c acids, providing valuable probes for local structure, dynamics, and ligand binding.

118 itoylation is governed by a distal secondary structure element rather than by local primary sequence.

119 Surrogate structures enable the rapid identification of parameters

120 Lipids have fundamental roles in the structure, energetics, and signaling of cells and organi

121 In this review, we outline the structure, evolution and function of these FASTK protein

122 on fitting of extended X-ray absorption fine structure (EXAFS) data using reference organic ligands d

123 No structural homologs or high-resolution structure exists for the TP domain.

124 mperature incommensurately modulated crystal structure (for Sm2Ru3Ge5 as a representative) have been

125 transfer is meticulously guided by transient structures formed from protein segments of low sequence

126 entification parameter and the assessment of structure-function relationships of drugs using IM-MS.

127 riation and the ability to conduct a careful structure-function study.

128 AB/PMMA matrix was then integrated over comb structured gold electrode array based sensor chip.

129 We here employ computational and structure-guided design to develop improved native-like

130 Structure-guided mutagenesis reveals that His175, Arg186

131 We exemplify current developments in structure-guided target identification and fragment-base

132 analysis and visualization of results using STRUCTURE HARVESTER.

133 photoconductive properties of GNRs, the edge structure has a strong impact on the carrier mobility in

134 Within-species variation in social structure has attracted interest recently because of the

135 Hierarchical structure has been cherished as a grammatical universal.

136 particles (MSNs) with controllable head-tail structures have been successfully synthesized.

137 Regardless, these amyloid structures illuminate the architecture of the amyloid st

138 Through the use of optical sectioning structured illumination microscopy (SIM), we have captur

139 Applying this labeling approach to structured illumination microscopy resulted in an increa

140 Functional analysis found that the RNA structure in MYB33 correlated with strong silencing effi

141 Unfortunately, the lack of structure in radiologic reports limits the ability of in

142 xtensive rearrangement of the macromolecular structure in response to force.

143 nchmark Structure-seq2 on both mRNA and rRNA structure in rice (Oryza sativa).

144 Eu evolves from the canted antiferromagnetic structure in the ground state, via a pure ferromagnetic

145 were recorded simultaneously from five brain structures in an awake mouse.

146 te the prevalence of sounds rich in harmonic structures in our everyday hearing environment, it has r

147 can create controllable hierarchical porous structures in stable MOFs, which facilitates the diffusi

148 ve and detailed map of the catecholaminergic structures in the brain of two representative species of

149 ve-sense RNA genomes replicate on membranous structures in the cytoplasm called replication complexes

150 cells (HSCs) undergo changes in function and structure, including skewing to myeloid lineages, lower

151 unts of PML and SP100 and the number of ND10 structures increase in cells exposed to IFN-beta.

152 The latter structure indicates how tension between the two motor do

153 two domains, which are conserved in sequence/structure indicating their importance to the virus.

154 ion in synaptojanin1 recruitment to clathrin structures, indicating broad control of CCP assembly by

155 both cases, topological features of network structures influence how easily distress can spread with

156 rse-led chemotherapy clinics, including semi-structured interviews with nurses.

157 ent features of DNA found in high-resolution structures introduce irregularities in the disposition o

158 a synergetic process and the whole carbonate structure is actively involved.

159 Bioassays indicate that this structure is associated with an increased antibiotic act

160 Subsequent genetic structure is attributed to Pleistocene climatic changes,

161 ps in hydrogen-bond stabilization of helical structures is a major factor, which determines sequence-

162 The formation of cell-in-cell structures is extensively studied in suspension cultures

163 ablishment of neuropil excitatory-inhibitory structure largely precedes dendritic arborization of pri

164 ges connecting conventional optical beam and structured light.

165 ut, thinned, cleared or otherwise altered in structure, local climates and microclimates change.

166 o the data compared with a non-nested factor structure model.

167 ) platform, iFoldNMR, for rapid and accurate structure modeling of complex RNAs.

168 BPEC) was used to detect four geographically structured mtDNA clusters.

169 f primary motor neurons, suggesting that the structured neuropil could provide a framework for the de

170 hly exothermic reaction to a classical Lewis structure nevertheless make us optimistic about the chan

171 the patterns of global spread and population structure of 277 RT017 isolates from animal and human or

172 The structure of a QuiC1 enzyme from P. putida reveals that

173 We report a 3.4-A resolution X-ray crystal structure of a sigma(N) fragment in complex with its cog

174 ds tetrahydropyrans (THPs) constitute a core structure of a wide array of bioactive natural products.

175 ence of temperature by determining the X-ray structure of Aqy1 at room temperature (RT) at 1.3 A reso

176 and reveals the high-resolution 3-D spatial structure of calcium gradients and intracellular fluxes

177 In a recent cryo-electron microscopy structure of chicken Slo2.2, the ion permeation pathway

178 e protective effect of the heme group on the structure of CYP142A1.

179 The NhaA crystal structure of Escherichia coli has become the paradigm fo

180 We present the structure of FBXW7 bound to the DISC1 phosphodegron moti

181 Streptomyces griseus We obtained the crystal structure of FNO in complex with NADP(+) at 1.8 A resolu

182 by forming a highly hierarchical chain-like structure of homogeneously clustered anatomical areas.

183 Furthermore, a post-chemistry structure of hPolbeta in the open conformation, followin

184 Here, we report the crystal structure of human XPNPEP3 with bound apstatin product a

185 We investigated the small molecule crystal structure of lead molecule 7 and hypothesized that disru

186 A third crystal structure of LmFBPase complexed with its allosteric inhi

187 d on our results, we postulate that the pore structure of many mineral soils could undergo N-dependen

188 Here, we report the cryo-electron microscopy structure of mature Japanese encephalitis virus at near-

189 Here we show the high-resolution structure of melon (Cucumis melo) eIF4E in complex with

190 odes SGCA, which is involved in the cellular structure of muscle fibers and, along with DMD, forms pa

191 n may underlie our ability to understand the structure of our social world and navigate within it.

192 The structure of PawS1 revealed that SFTI-1 and the albumin

193 nd technological importance, the interfacial structure of R5 during silica precipitation remains poor

194 n the same way DNA was modeled, the tertiary structure of RNA is constrained using an elastic network

195 However, due to the ultra-flat aromatic structure of SN-38, it is typically very difficult to pr

196 Although the atomic structure of T4 is largely known, the dynamics of its fa

197 The 3.3-A cryo-EM structure of the 860-A-diameter isometric mutant bacteri

198 Here we present the structure of the beta2AR bound to a polyethylene glycol-

199 tracks has not advanced for decades and the structure of the cells that form them, denervated or rep

200 The structure of the competitive network is an important dri

201 o have promising antimicrobial activity, the structure of the conformationally flexible molecules was

202 esolution cryo-electron microscopy (cryo-EM) structure of the core tetrameric HIV-1 STC and a higher-

203 Here, we present the structure of the Fab fragment of such an antibody.

204 By solving the crystal structure of the IL-1alpha/aptamer, we provide a high-re

205 g approach, we determine the high-resolution structure of the radiation sensitive molybdenum storage

206 These findings illustrate that the secondary structure of the RNA molecule-and its absence-plays an e

207 nds on segment length, the type of secondary structure of the segment and local quality of the map.

208 Here, we present the crystal structure of the SNX5-PX:IncE complex, showing IncE boun

209 ssful, gives an accurate and unambiguous 3-D structure of the structurally unknown guest molecule fro

210 n between the air-stability of CuNPs and the structure of the thiolate capping ligand; of the eight d

211 Here we present the crystal structure of the trimeric, prefusion ectodomain of Lassa

212 However, the structure of the viral major capsid protein, elucidated

213 a response that is dependent on the spatial structure of the visual environment.

214 However, knowledge of the structure of these regeneration tracks has not advanced

215 ation analysis due to the similarity in data structure of these two types of researches.

216 We also solve the structure of this complex by negative stain electron mic

217 1alpha/aptamer, we provide a high-resolution structure of this critical cytokine and we reveal its fu

218 ring animal development and homeostasis, the structure of tissues, including muscles, blood vessels,

219 Here, we report the cryoEM structure of yeast U1 snRNP at 3.6 A resolution with ato

220 We report the structures of a TRBV9(+) TCR in complex with the HLA-E m

221 The crystal structures of apo PllA and complexes with three differen

222 Previous crystal structures of cytochrome P450cam complexed with its redo

223 The sophisticated tail structures of DNA bacteriophages play essential roles in

224 dopsis thaliana We observed that the crystal structures of free, Mg(2+)-bound, and beryllofluoridated

225 Nature has evolved hierarchical structures of hybrid materials with excellent mechanical

226 ture of the TFIIH core complex, the detailed structures of its constituent XPB and XPD ATPases, and h

227 on sustained specific three-dimensional (3D) structures of RNA, with or without the help of proteins.

228 is structure with inactive- and active-state structures of the beta2AR reveals the mechanism by which

229 Crystal structures of the muPA:nanobody complexes and hydrogen-d

230 Here we solve the crystal structures of the N-terminal domains of PHF1 and MTF2 wi

231 esent two additional high-resolution crystal structures of the same RNA duplex containing four and ei

232 Two structures of this segment determined by the cryo-electr

233 cking interactions by analyzing experimental structures of urea transporters and proteins crystallize

234 The modular nature of their layered structures offers opportunities for the construction of

235 For species with dispersal structures on their seeds, plant height is very weakly r

236 enormous compound eyes, but not the internal structures or anything about how those compound eyes may

237 del to accommodate changes in the modulatory structure over the duration of the experiment, and there

238 otein characterized by a relatively flexible structure, particularly in the ferric form, such that it

239 djacencies can be included as constraints in structure prediction techniques to predict high-resoluti

240 periodic table (group number) influence the structure preference.

241 The exploration of molecular structure-property relations is crucial to optimize gamm

242 Both structures provide molecular insights into malonate deca

243 This refined structure provided a significantly improved fit of exper

244 Importantly, this nested factor structure provided better overall fit to the data compar

245 ore generally, the insights gained from this structure-reactivity relationship may aid in the develop

246 that structure diversification, rather than structure refinement, is the driving force behind the cr

247 Genetic diversity and population structure reflect complex interactions among a diverse s

248 SCOPe classifies the majority of protein structures released since SCOP development concluded in

249 t studies show that there is sufficient cone structure remaining in the central fovea of BCM patients

250 eversible I2 uptake of 1.54 g g(-1), and its structure remains completely unperturbed upon inclusion/

251 and damage-resistant nature, we termed these structures "renitence vacuoles" (RVs).

252 The tetramers share several features with structures reported for IAPP fibrils and demonstrate the

253 These structures reveal an unexpected tripartite interface bet

254 These structures reveal that an unusual monodentate Zn(2+) coo

255 The Axl crystal structure revealed two distinct conformational states of

256 Our structure reveals a dramatic conformational change in a

257 ith acetyl coenzyme A and an X-ray cocrystal structure reveals that binding is biased toward occupati

258 The structure reveals the molecular architecture of the TFII

259 Additionally, analysis of symmetric device structures reveals propagating polarization domains.

260 We benchmark Structure-seq2 on both mRNA and rRNA structure in rice (

261 The structure shows that POT1C contains two domains, a third

262 different number of coils, forming a plasma structure similar to that observed in the experiment.

263 gal forests, important ecosystems whose main structuring species is the annual kelp Saccorhiza polysc

264 development of machine learning and network structure study provides a great chance to solve the pro

265 thod may also prove useful for imaging other structures, such as neurons in the brain.

266 r is broken in heterodimeric reaction-center structures, such as those reported previously.

267 The structures suggest a mechanism for iron mineral formatio

268 The WhiB1 structure suggests that loss of the iron-sulfur cluster

269 nd provide new insights into GB1:IgG complex structure that amend and revise the current model availa

270 at regions refold to form a six-helix bundle structure that can be specifically targeted by fusion-in

271 foldamers yields a new and unique secondary structure that we term an "eta-helix" due to its repeati

272 that it features a double-Q conical magnetic structure that, apart from trivial 180(o) commensurate m

273 substituted tetrahydroisoquinolines (THIQs), structures that are challenging to synthesize and yet ar

274 Surprisingly, in all three structures, the bulky and hydrophobic BP pyrenyl residue

275 alized AuNPs which form DNA-RNA heteroduplex structures through specific hybridization with target DN

276 m6A can also alter RNA structures to affect RNA-protein interactions in cells.

277 that adopt the most populated ternary 1:1:1 structure types (TiNiSi-, ZrNiAl-, PbFCl-, LiGaGe-, YPtA

278 we report the experimental discovery of two structure types by computational identification of the r

279 , including the sheet-on-sheet sandwich-like structure, ultrathin nanosheets with abundant nanopores,

280 Their structure under confinement is far less well understood.

281 inally to an "unconfirmed" antiferromagnetic structure under the high pressure.

282 n the ground state, via a pure ferromagnetic structure under the intermediate pressure, finally to an

283 Upon decompression, the fcc-based structure undergoes a rhombohedral distortion of the La

284 clear whether the same river properties that structure variation on recent timescales will also leave

285 The structure was fitted into an existing SAGA EM reconstruc

286 Gene structure was improved in over 13% of genes, and 651 nov

287 Here, we describe a structure we refer to as the embryo sheath that forms on

288 By utilizing these novel structures we show that (i) the detection limit for dopa

289 Given its unusual structure, we investigated the biophysical properties of

290 Based on the atomic structure, we propose a local seeding model where the ki

291 ture- and field-dependent evolution of these structures, we observe several new features.

292 oltages of the circuit reflecting the vessel structures were used for node registration.

293 32:Cas14) into a four-lobed propeller-shaped structure, where the two Cas2 domains form a central hub

294 A possesses a unique CPS locus with a mosaic structure, which has been stably maintained in all clone

295 nd density functional theory (DFT)-optimized structures, which binds choline in a unique dual-site-bi

296 A comparison of this structure with inactive- and active-state structures of

297 tive Mn2MnWO6, which adopts the Ni3TeO6-type structure with low temperature first-order field-induced

298 n I in the maintenance of mitotic chromosome structure with unprecedented temporal resolution.

299 The reaction couples structured with TFMG/TE are annealed at 673 K for 8-360

300 ndidates are first identified by focusing on structures with methane-inaccessible pores blocked away