1 spective, double-blind, multicentre, phase 3
studies (UNCOVER-
2 and UNCOVER-3), eligible patients wer
2 Our
studies uncover a cell-cycle-independent function of Cdh
3 These
studies uncover a critical role for the Tsc2/mTOR pathwa
4 Thus, our
studies uncover a crucial role for Olig2 in white matter
5 Our
studies uncover a direct role for TAZ and TEAD in drivin
6 Our
studies uncover a hierarchical GPI-receptor signaling ne
7 Our
studies uncover a highly efficient method for directed M
8 Collectively, our
studies uncover a mechanism by which BAF155 acquires tum
9 These
studies uncover a mode of epithelial closure in which fo
10 Genetic
studies uncover a mutation in a widely conserved protein
11 Two new
studies uncover a new facet of its regulation in epithel
12 Our
studies uncover a new function for polyadenylation in co
13 Our
studies uncover a new locus-specific effect of the conde
14 Taken together, our
studies uncover a new metastasis-promoting pathway in Ew
15 Together, our
studies uncover a new role for BMP signaling in the regu
16 Recent
studies uncover a novel function of CREB-H in the regula
17 Our
studies uncover a novel function of the TOR pathway in r
18 Our
studies uncover a novel invasive podosome-like structure
19 Our
studies uncover a novel link between MLH1, telomerase, t
20 Our
studies uncover a novel mechanism through which the diox
21 These
studies uncover a novel paradigm in Notch signaling and
22 Thus, our
studies uncover a novel role for adiponectin signaling i
23 Our
studies uncover a novel role of the tubular beta-catenin
24 These
studies uncover a p53-Ptpn14-Yap pathway that is integra
25 These
studies uncover a potential role for recurrent RNA chime
26 Our
studies uncover a previously unappreciated role for IMPb
27 Taken together, our
studies uncover a previously unidentified role for Hh as
28 These
studies uncover a previously unrecognized function for K
29 Our
studies uncover a previously unsuspected role of pDCs in
30 These
studies uncover a rate-limiting ET within the solvent-fi
31 These
studies uncover a role for AKAP-Lbc in which increased e
32 These
studies uncover a role for miR-148a as a key regulator o
33 Our
studies uncover a role for the chromatin factor SIRT6 as
34 Recent structural and biophysical
studies uncover a role for the opening or rotating of th
35 These
studies uncover a role for vigilin as a key regulator of
36 These
studies uncover a speed control mechanism that might all
37 These
studies uncover a transcriptional feedback loop for becl
38 Mechanistic
studies uncovered a common theme of translational inhibi
39 Our
studies uncovered a diverse family of promoters (P) for
40 Metabolic
studies uncovered a limited ability of ischemic hearts i
41 Genome-wide association
studies uncovered a major atrial fibrillation susceptibi
42 Collectively, our
studies uncovered a novel function of E3 ligase activity
43 oint analyses as well as electron microscopy
studies uncovered a role for B1 during maturation of pox
44 Our recent
studies uncovered a role for Fyn in promoting BCR-ABL1 m
45 These
studies uncovered a role for the ECD as an intrinsic neg
46 Genetic interaction
studies uncovered a synergistic interaction between miRN
47 Collectively, our
studies uncovered a unique conserved pathway involving B
48 The results of the present
study uncover a link between transcriptional and epigene
49 The results of the present
study uncover a new function for an olfactory bulb neuro
50 The findings in this
study uncover a potential target for cervical cancer pre
51 Our
study uncovered a critical molecular crosstalk between T
52 Taken together, our
study uncovered a mechanism that EV71 utilizes to promot
53 Thus, our
study uncovered a molecular mechanism whereby RasC activ
54 This
study uncovered a new function of Cdc6 in regulating cel
55 Thus, our
study uncovered a new role for APX6, in protecting matur
56 Therefore our
study uncovered a new signaling pathway that involves Ra
57 Our
study uncovered a novel carrier-mediated pathway for dru
58 Collectively, this
study uncovered a novel function of VEGF, namely, on-sit
59 Our
study uncovered a novel mechanism for the preferential r
60 Taken together, this
study uncovered a novel mechanism in vascular tissue pat
61 Thus, our
study uncovered a novel metabolic function of hepatic BM
62 This
study uncovered a novel role for YopJ in the activation
63 The
study uncovered a possible physiological role for Nrf2 i
64 This
study uncovered a role for ARF3 in FM determinacy and re
65 Our previous
study uncovered a unique consequence of hybridization in
66 This
study uncovers a BTLA-mediated strategy used by the host
67 A new
study uncovers a central role for microtubule motor-regu
68 This
study uncovers a cholesterol-miR-33-RIP140 regulatory pa
69 Our
study uncovers a complex regulatory network for the meta
70 Our
study uncovers a connection between transcription and ch
71 Our
study uncovers a critical mechanism of immunosuppression
72 Our
study uncovers a critical role for Ape1 in DNA repair pa
73 Hence, this
study uncovers a critical role for MYSM1 in epigenetical
74 Thus, the present
study uncovers a critical role of TH in promoting the th
75 This
study uncovers a dual role for Vps34 as a regulator of p
76 Our
study uncovers a function of SRC in cell-cell communicat
77 This
study uncovers a fundamental difference between haplopha
78 Our
study uncovers a fundamental relationship whereby cell c
79 This
study uncovers a fundamental role for the skeletal muscl
80 Our
study uncovers a hierarchical, SLM2-dependent mechanism
81 This
study uncovers a historic role of wild Solanum species i
82 Our
study uncovers a hitherto unknown biochemical pathway in
83 Hence, our
study uncovers a JNK-Hh-JAK-STAT signaling axis in the r
84 This
study uncovers a key missing player in the cytoskeleton-
85 Thus, our
study uncovers a link between a cytoskeleton-based pathw
86 Our
study uncovers a local crosstalk between mast cells and
87 Thus, our
study uncovers a local repulsive mechanism required for
88 This
study uncovers a mechanism by which Hof1 controls timely
89 This
study uncovers a mechanism by which maspin exerts its ef
90 Taken together, our
study uncovers a mechanism of azole resistance in C. alb
91 Our
study uncovers a mechanism that links the remodeling of
92 Our
study uncovers a mechanism whereby co-existing cytoplasm
93 This
study uncovers a molecular cross talk between WNT/beta-c
94 This
study uncovers a new function for IRF5 in controlling th
95 Our
study uncovers a new mechanism by which FXR negatively r
96 Our
study uncovers a new mechanism for BAP1 involved in deub
97 Our
study uncovers a new mechanism of action for DISC1 based
98 Our
study uncovers a new pathway that controls synaptic APP
99 Our
study uncovers a new regulatory pathway involving miR-19
100 Our
study uncovers a new role of mechanical tension in neura
101 Our
study uncovers a noncanonical thermogenic mechanism thro
102 Overall, our
study uncovers a novel ability of TIM-family proteins to
103 Our
study uncovers a novel aspect of endothelial cell migrat
104 This
study uncovers a novel class of dual inhibitors of DUBs
105 Our
study uncovers a novel cross-talk between LGR5 and TGFbe
106 Collectively, our
study uncovers a novel epigenetic mechanism regulating E
107 This
study uncovers a novel epigenetic RNAi-based epimutation
108 This
study uncovers a novel function for MDSCs to inhibit B l
109 Collectively, our
study uncovers a novel function of NLRP3 by demonstratin
110 Our
study uncovers a novel function of TNKS in the relief of
111 n of a new mechanism of action for RITA, our
study uncovers a novel link between the DNA damage respo
112 In conclusion, this
study uncovers a novel mechanism controlling beta-AR res
113 This
study uncovers a novel mechanism of nitric oxide product
114 Our
study uncovers a novel mechanism of somatic cell differe
115 This
study uncovers a novel mechanism regulating polarized pr
116 This
study uncovers a novel mechanism where a phosphoinositid
117 Our
study uncovers a novel molecular mechanism by which AEG-
118 Our
study uncovers a novel molecular mechanism for regulatin
119 Thus, our
study uncovers a novel regulatory mechanism for the deve
120 Collectively, our
study uncovers a novel regulatory mechanism mediating bo
121 This
study uncovers a novel role for calpain in the endotheli
122 Our
study uncovers a novel role of Bcl2 in HSC quiescence re
123 Collectively, our
study uncovers a novel role of HS-type glycosaminoglycan
124 Together, our
study uncovers a novel signaling circuit functioning to
125 Our
study uncovers a novel tumor suppressor role of ZBTB7A i
126 Thus, our
study uncovers a PAR-dependent mechanism of rapid recrui
127 Our
study uncovers a PML degradation mechanism through Notch
128 5 is safe and well tolerated in humans, this
study uncovers a potential therapeutic approach for HF a
129 Our
study uncovers a premeiotic role for an invertebrate bou
130 Collectively, our
study uncovers a previously unappreciated role of PML in
131 Our
study uncovers a previously uncharacterized interaction
132 Our
study uncovers a previously undefined role of innate leu
133 This
study uncovers a previously unknown explanation for why
134 Our
study uncovers a previously unknown mechanism by which a
135 Our
study uncovers a previously unknown mechanism by which G
136 Our
study uncovers a previously unknown mechanism for the in
137 In sum, our
study uncovers a previously unknown mechanism in which R
138 Thus, our
study uncovers a previously unknown mechanism of radiore
139 Our
study uncovers a previously unknown mechanism that gover
140 Our
study uncovers a previously unknown relationship between
141 Our
study uncovers a previously unknown relationship between
142 Thus, this
study uncovers a previously unknown role of MT6/MMP25 in
143 Collectively, our
study uncovers a previously unknown tightly coupled posi
144 This
study uncovers a previously unrecognized dominant functi
145 Our
study uncovers a previously unrecognized mechanism by wh
146 Collectively, our
study uncovers a protein complex, which consists of FIGN
147 posure therapies.SIGNIFICANCE STATEMENT This
study uncovers a reciprocal relationship between dendrit
148 Thus, this
study uncovers a regulatory mechanism of the vSMC phenot
149 Altogether, our
study uncovers a regulatory mechanism underlying liver c
150 Thus, our
study uncovers a regulatory network to segregate related
151 Our field and laboratory
study uncovers a rich sexual repertoire that predictably
152 This
study uncovers a role for BR in the spatiotemporal contr
153 A new
study uncovers a role for the DNA methyltransferase Dnmt
154 This
study uncovers a role of Glis3 for regulation of insulin
155 This
study uncovers a role of HEY2 in the normal transmural e
156 Taken together, our
study uncovers a role of TTP as a suppressor of feedback
157 This
study uncovers a strategy that will allow for highly eff
158 Overall, this
study uncovers a strong connection between chromatin re-
159 This
study uncovers a strong reciprocal interdependence betwe
160 Together, our
study uncovers a TET1/GFI1/EZH2/SIN3A/miR-22/CREB-MYC si
161 Our
study uncovers a unique antibacterial role for HMOs agai
162 In summary, this
study uncovers a unique biological consequence of profil
163 Together, this
study uncovers a unique molecular mechanism of lymphangi
164 Our
study uncovered abnormalities in rapidly proliferating S
165 Our
studies uncover an alternative target and function for t
166 Altogether, our
studies uncover an essential role for DNMT1 in MaSC and
167 Furthermore, our
studies uncover an important role of MRN, CtIP, and thei
168 Our
studies uncover an indispensable role of APP in the GABA
169 These
studies uncover an RNA-mediated mechanism of targeting A
170 In summary, these
studies uncover an unexpected signaling mechanism for ac
171 Our
study uncovered an important role of SHP2 in bone develo
172 Our
study uncovered an unexpected novel function of CD81 in
173 Furthermore, this
study uncovers an additional contribution of kinase acti
174 This
study uncovers an anti-sense lncRNA (APOA4-AS), which is
175 Altogether, our
study uncovers an autophagy master switch regulating the
176 This
study uncovers an essential function for Six1 in the MM
177 This
study uncovers an essential role for ANKS4B in brush bor
178 Our
study uncovers an essential role for FA proteins in main
179 This
study uncovers an essential role for Shh signalling in t
180 Furthermore, our
study uncovers an important contribution of the non-kina
181 Therefore, this
study uncovers an important role for TLX and miR-219 in
182 Our
study uncovers an inf-DC-gammadeltaT17-PMN-MDSC regulato
183 Our
study uncovers an interesting aspect of the evolution of
184 Thus, the present
study uncovers an interesting phenomenon that rs17849071
185 Our
study uncovers an interplay between intrinsic DISC1 and
186 Therefore, our
study uncovers an oncogenic role of EZH2 independent of
187 Thus, our
study uncovers an unforeseen role of CaN in postsynaptic
188 This
study uncovers and investigates the effect of phosphatid
189 Taken together, these
studies uncover ANK3 and other genes in our dataset as b
190 Our current
study uncovers both a proliferative and novel antiapopto
191 Collectively, our
study uncovers both separate and interdependent Brd2 and
192 These
studies uncover cell-autonomous injury by SOD1 to motor
193 risons become apparent using gar: functional
studies uncovered conserved roles for such cryptic CNEs,
194 This
study uncovers critical redox control of tumor plasticit
195 These
studies uncover crucial proinflammatory mechanisms of An
196 Further
studies uncovered defects related to MAP kinase I (Slt2)
197 Our
studies uncover design similarities between LCD and deve
198 This
study uncovered differences in the fatty acid selectivit
199 Our
study uncovers differential and context-dependent effect
200 Mechanistic
studies uncovered distinct catalytic activities and reac
201 Our
study uncovers dynamic changes in Wnt/beta-catenin signa
202 The present
study uncovers epithelial-to-mesenchymal transition as a
203 Results from this
study uncover essential roles of the PCM progenitors dur
204 Our
study uncovers essential roles of Afadin and RhoA in pan
205 Together, our
study uncovers evolutionarily important determinants of
206 Our
study uncovered extensive networks of peptidergic signal
207 The present
study uncovers for the first time a novel role of Cited2
208 Together, this
study uncovers for the first time the molecular mechanis
209 Taken together, our
study uncovers,
for the first time, that RECK is a novel
210 Thus, this
study uncovered fundamental differences between HDAC1 an
211 Our
study uncovers genes required for lineage specification
212 Genetical genomics
studies uncover genome-wide genetic interactions between
213 Therefore, our
study uncovers GRKs as targets for ameliorating patholog
214 Genetic
studies uncovered heterozygous missense mutations in SAM
215 A new
study uncovers how two plants connect and demonstrates t
216 Our
study uncovers human PRKCD deficiency as a novel cause o
217 Thus, our
study uncovers Hxk2 as a new cargo for the alpha/beta-im
218 Our
study uncovers IL-21 deficiency as a novel cause of earl
219 These
studies uncover important connections between inflammati
220 Our
study uncovered induction of NFATc2 in late-stage pancre
221 Our
study uncovers key roles for TNF and, to a lesser extent
222 Together, the results from our
study uncover lineage-related and molecular logic of sub
223 Although earlier
studies uncovered loci that undergo age-associated DNAm
224 Together, our
study uncovered many previously uncharacterized represso
225 Collectively, this
study uncovers mechanisms underlying the therapeutic eff
226 Taken together, our
study uncovers mechanisms underlying ZIKV neuropathogene
227 Our
studies uncover miR-22 as a critical regulator of cardio
228 Thus, our
study uncovered miRNA signatures during monocyte differe
229 These
studies uncover new paradigms for the preferential speci
230 In summary, this
study uncovered new mutations associated with TAC resist
231 In sum, this
study uncovers new anatomical and functional modules of
232 Our
study uncovers new features of RNA recognition and splic
233 This
study uncovers new metabolic checkpoints for T cell acti
234 Our
studies uncover Nf2 as an important inhibitor of neural
235 Furthermore, these mapping
studies uncover nodules in the pharyngeal arches, and id
236 Our
studies uncover novel functions of MSN subtypes in depre
237 Our
studies uncover opportunities for simultaneously treatin
238 Our molecular and genetic
studies uncover PI3K/AKT2 as a direct PDGFA target that
239 More significantly, the
study uncovered previously unreported phenotypes for the
240 Taken together, this
study uncovers previously unrecognized cellular mechanis
241 Ultrastructural
studies uncovered progressive dilation of the sarcoplasm
242 Altogether, our
studies uncover Rab34/Munc13-2 as a critical part of an
243 Our
study uncovers RagA/B GTPases as key regulators of lysos
244 Collectively, our
study uncovers REST in regulating EMT and stemness prope
245 Equilibrium
studies uncover segregation at the solid-like surface of
246 Together, this
study uncovering Skp2-mediated Twist stabilization and o
247 Recent
studies uncovering some of the signaling pathways import
248 In vivo combination
studies uncovered surprising benefits of low doses of AB
249 This
study uncovers synergistic activation of Arg1 by RA and
250 These
studies uncovered synthetic interactions between los1Del
251 Mechanistic
studies uncover that the activated ROS1 results from hig
252 Electrophysiology and EM
studies uncovered that the number of multigranular compo
253 Taken together, this
study uncovered that CdpR is an important QS regulator,
254 This
study uncovers that a lipid pathway promotes neuronal fu
255 Taken together, our
study uncovers that the capacity of vacuolar Cl(-) loadi
256 This
study uncovers that the response to hyperglycemia in vas
257 These
studies uncover the action of polyomavirus T antigens on
258 These
studies uncover the biological significance of bone marr
259 Our
studies uncover the complement of planarian GPCRs and re
260 These
studies uncover the energetics and geometry for mutual r
261 Our
studies uncover the underlying kinetic basis for a class
262 cryo-electron tomography and thin-section EM
studies uncovered the assembly and maturation pathway of
263 These
studies uncovered the involvement of cellular programs t
264 Although pharmacological
studies uncovered the involvement of D2-class dopamine r
265 ep and wake to lay the foundation for future
studies uncovering the mechanisms that underlie the init
266 Future
studies uncovering the posttranscriptional networks in h
267 Altogether, our
study uncovered the existence of a novel Akt-HSF-1 signa
268 Our
study uncovers the 1q21.3-directed S100A7/8/9-IRAK1 feed
269 This
study uncovers the defensive function of JA signaling in
270 Our
study uncovers the essential requirement of Swe1 to modu
271 Our
study uncovers the evolutionary strategies by which vacc
272 This
study uncovers the existence of a second endocrine axis
273 Our
study uncovers the first genetic evidence explaining why
274 Our
study uncovers the loss-of-function mutation in ZBTB7A a
275 Our
study uncovers the mechanism by which extrinsic RA-signa
276 This
study uncovers the metabolic mechanisms by which IL-7 ta
277 Our
study uncovers the molecular architecture and evolution
278 This
study uncovers the molecular bases responsible for the d
279 This
study uncovers the molecular function of the natural var
280 Our
study uncovers the molecular heterogeneity of SLE and pr
281 This
study uncovers the opportunity to use properties of hepa
282 Our
study uncovers the pathogenic mechanism whereby absence
283 Our
study uncovers the postsynaptic function of the SNAP25-V
284 This
study uncovers the role for general splicing machinery i
285 Our
study uncovers the role of chirality in defining the mes
286 This
study uncovers the role of temperature in environmental
287 This
study uncovers the role of weak noncovalent interactions
288 Our
study uncovers the signaling and cellular mechanism by w
289 Our
study uncovers the structural basis for LPS recognition,
290 Collectively, these
studies uncover total urinary protease, PG D synthase, S
291 This
study uncovers two competing processes triggered by viru
292 Our
study uncovers two distinct mechanisms by which motivati
293 Our
study uncovers unexpected differences between monocytes
294 In addition, the
study uncovers unexpected exosomal transfer of this micr
295 This
study uncovers unexpected similarities but also differen
296 Recent
studies uncover unexpectedly important roles for Fcgamma
297 Our
study uncovers unknown effects of RT delivered on a woun
298 These
studies uncover VCAM-1, P-selectin, TNFR-1, and CXCL16 a
299 Furthermore, our
study uncovered well known and new PPXY-WW1-interacting
300 Together, our
studies uncover what we believe are novel miRNA-dependen