ライフサイエンスコーパス: subcellular distribution

1 ith age and SSc, and they exhibit an altered subcellular distribution.

2 pe littermates but still maintained a normal subcellular distribution.

3 and overlapping controls over expression and subcellular distribution.

4 molecular determinants of TRPV4 activity and subcellular distribution.

5 lized proteins exhibited prominent cytosolic subcellular distribution.

6 h a loss of restriction and an alteration of subcellular distribution.

7 fluorescent reporter of CaMKII activity and subcellular distribution.

8 2+) in cells, very little is known about its subcellular distribution.

9 nhibited HDAC3 activity but also altered its subcellular distribution.

10 ble, present lipid Ags, and have near normal subcellular distribution.

11 uenced incorporation into COPII vesicles and subcellular distribution.

12 2 by the G2-phase kinase Cdk1 influences its subcellular distribution.

13 residues Ser(168,170) of NFATc4, to regulate subcellular distribution.

14 gate-keeping Ser residues that control NFAT subcellular distribution.

15 demonstrates that most RNAs exhibit specific subcellular distribution.

16 nctions of GRP78 may result from its diverse subcellular distribution.

17 2 treatment while maintaining its unexpected subcellular distribution.

18 homologue Kes1/Osh4 and regulate ergosterol subcellular distribution.

19 cluster size as a primary determinant of its subcellular distribution.

20 in interaction with VAMPs and affected their subcellular distribution.

21 odification that could possibly regulate its subcellular distribution.

22 Villin and Profilin, do not exhibit the same subcellular distribution.

23 vities, likely through mechanisms related to subcellular distribution.

24 C progression regulation was dictated by its subcellular distribution.

25 forms that differ mainly in their tissue and subcellular distribution.

26 These functions are controlled partly by its subcellular distribution.

27 interneurons have distinct subglomerular and subcellular distributions.

28 m to regulate their catalytic activities and subcellular distributions.

29 mechanotransduction channels with different subcellular distributions.

30 tau protein in glaucoma, including abnormal subcellular distribution, an altered phosphorylation pro

31 nitiated Akt-GSK3beta signaling mediates the subcellular distribution and activation of GLI1 resultin

32 ed a new regulatory site that controls Bax's subcellular distribution and activation.

33 patients truncates the protein, impairs its subcellular distribution and adversely affects its funct

34 periments revealed that trehalose alters the subcellular distribution and decreases the degradation o

35 the importance of tRNA for translation, its subcellular distribution and diffusion properties in liv

36 igated the mechanisms of p53-dependent BRCA1 subcellular distribution and DNA damage-induced nuclear

37 two conflicting hypotheses by evaluating the subcellular distribution and dynamics of Gal3 and Gal80

38 teins with an Ig-like domain, share the same subcellular distribution and ectodomain shedding propert

39 nd computational modeling to investigate the subcellular distribution and effects of GABA(B)Rs and th

40 aling, in turn, was found to influence Spry2 subcellular distribution and ERK, a Spry2 regulator.

41 ogical and optical approaches to examine the subcellular distribution and function of hyperpolarizati

42 Here we characterize the subcellular distribution and function of PS in the rod-s

43 ls and suggest mechanisms to account for the subcellular distribution and function of this phospholip

44 e report the first characterization of their subcellular distribution and identify a specific associa

45 me), a protein complex for which the precise subcellular distribution and mechanisms of action are un

46 Both approaches revealed similar subcellular distribution and membrane binding for both t

47 unknowns, including in vivo enzymatic rates, subcellular distribution and pathway interactions.

48 e are signal transduction centers, yet their subcellular distribution and preservation in cardiac myo

49 Here we systematically investigated the subcellular distribution and processing of major NRG iso

50 The depletion of CEP290 disrupts subcellular distribution and protein complex formation o

51 Subcellular distribution and protein expression levels i

52 TS-associated missense mutations alter their subcellular distribution and protein interactions, compr

53 2 genotype with NRG1-IVNV expression and the subcellular distribution and proteolytic processing of N

54 late Numb signaling through changes in ACBD3 subcellular distribution and represent a mechanism for c

55 n, and morphological analysis to examine the subcellular distribution and requirements for AtCDC48A i

56 le of caveolin-1 (Cav-1) in modulating P2Y2R subcellular distribution and signaling in human 1321N1 a

57 This chaperone system influences both the subcellular distribution and the 66/55 kDa protein ratio

58 ysically binds Vangl2 and regulates both the subcellular distribution and total protein level of Vang

59 Subcellular distribution and trafficking of labile Zn(2+

60 al questions about oxysterols, such as their subcellular distribution and trafficking pathways, remai

61 nkG expression caused significant changes in subcellular distribution and/or abundance of PKP2 and Co

62 Despite their similarity, the subcellular distributions and functional properties of m

63 ajor factors that determine cellular uptake, subcellular distribution, and as a consequence, the phot

64 potency, this compound has the permeability, subcellular distribution, and cell metabolism characteri

65 vels of expression (which vary by >30-fold), subcellular distribution, and coimmunoprecipitation anal

66 induced alterations in transporter activity, subcellular distribution, and dopamine efflux, but the r

67 er, the mechanisms regulating Alix turnover, subcellular distribution, and function in muscle cells a

68 arious molecular weight forms of K15P, their subcellular distribution, and how these may differ in la

69 the dDis3 N-terminus also contributes to its subcellular distribution, and is necessary and sufficien

70 e activity of JMY in vitro and in cells, its subcellular distribution, and its function in fibroblast

71 is mechanism uses changes in the morphology, subcellular distribution, and molecular composition of c

72 photosensitizer (PS) affect cellular uptake, subcellular distribution, and photodynamic efficacy.

73 n membrane topology, protein processing, and subcellular distribution, and suggest that single- and d

74 -3 cDNA, and effects on beta-catenin levels, subcellular distribution, and Wnt signaling were determi

75 ributed to differences in protein stability, subcellular distribution, and/or RNA binding and virion

76 Changes in AQP4 subcellular distribution are associated with several neu

77 The protein shows a highly dynamic subcellular distribution between cytoplasm and flagellar

78 the tRNA reexport process and show that its subcellular distribution between the nucleus and cytopla

79 AR S-nitrosylation does not impact its subcellular distribution but attenuates its ability to b

80 Our findings show that EGFR subcellular distribution can modulate DNA repair kinetic

81 However, USP18-sf shows different subcellular distribution compared with the full-length p

82 However, automated quantification of MR subcellular distribution demonstrated that finerenone de

83 y affected dopamine transporter function and subcellular distribution depending on the duration of ag

84 unable to bind to CPSF3 did not alter CPSF3 subcellular distribution, did not inhibit its polyadenyl

85 However, their subcellular distributions differed, as only CEL-MUT was

86 The importance of the subcellular distribution for the signaling activity of K

87 These data reveal a novel subcellular distribution for ZNF804A within somatodendri

88 under conditions of cell stress changes its subcellular distribution from peroxisomes to the nucleus

89 but, unlike other inducers, also shifts its subcellular distribution from the cytosol to the nucleus

90 fy tyrosine kinase substrates based on their subcellular distribution from within cells.

91 ts expression relative to other calpains and subcellular distribution has not been investigated previ

92 nt protein and systematically surveyed their subcellular distribution, identifying enzymes specific t

93 n vitro and in situ, PIST displayed a patchy subcellular distribution in an area surrounding the nucl

94 However, their subcellular distribution in AVP or OC neurons of the PVN

95 anscriptional activity, without altering its subcellular distribution in hepatocytes.

96 That IIA and IIB assume distinct subcellular distribution in migrating cells suggests tha

97 ng the factors regulating muscle LIM protein subcellular distribution in myocytes.

98 ons, although GIRK2c achieved a more uniform subcellular distribution in pyramidal neurons and suppor

99 creased synthesis of AMPAR subunits on their subcellular distribution in rat hippocampal neurons.

100 The GRK5 subcellular distribution in the human striatal neurons i

101 first electron microscopy (EM) study of S1R subcellular distribution in the mouse retina.

102 munofluorescence analysis showed that L(pro) subcellular distribution is altered in cells infected wi

103 sion, DCT post-translational processing, and subcellular distribution is cell phenotype-dependent.

104 In myocytes, muscle LIM protein subcellular distribution is regulated by cell contractil

105 gest that the Abeta-induced change in CaMKII subcellular distribution may underlie the removal of AMP

106 The subcellular distribution of (64)Cu was measured by cell

107 phosphorylation on Ser-523, to determine the subcellular distribution of 5-LO, which in turn regulate

108 determine the tissue-specific expression and subcellular distribution of 5862 mRNAs during Drosophila

109 Dissecting the subcellular distribution of a fatty-acylated protein is

110 y, we show that Wnt5a is required for proper subcellular distribution of a PCP protein, Ltap/Vangl2,

111 icant changes in the expression level or the subcellular distribution of ABCB1 and ABCG2 in the cells

112 TGF-beta-mediated ERK signaling, altered the subcellular distribution of activated ERK, and inhibited

113 Furthermore, changes in subcellular distribution of active focal adhesion kinase

114 Moreover, Cdh6 knockdown alters the subcellular distribution of active Rho, which is known t

115 ovide the first convincing evidence that the subcellular distribution of Ago2 occurs in a cell type-

116 emistry to study the regional, cellular, and subcellular distribution of AIDA-1.

117 al neuron subtypes that express AKAP150, the subcellular distribution of AKAP150, and the potential t

118 d that ATXN1 interacts with and controls the subcellular distribution of Alt-ATXN1.

119 The subunit composition and subcellular distribution of AMPARs and NMDARs are theref

120 ery little is known about the expression and subcellular distribution of ANG in the nervous system or

121 High expression or aberrant subcellular distribution of Ape1 has been detected in ma

122 Surprisingly, the subcellular distribution of AQP4 clusters was different

123 We have characterized the expression and subcellular distribution of Arabidopsis thaliana ARP5 an

124 Dact1/2 regulate the subcellular distribution of beta-catenin, preventing bet

125 Western blot analysis were used to determine subcellular distribution of beta-catenin.

126 Accordingly, mechanisms triggering the subcellular distribution of both enzymes have been unexp

127 dney (HEK) 293 or INS1(832/13) cells and the subcellular distribution of c-myc-tagged SUR1 channels a

128 Finally, an analysis of the subcellular distribution of C5aR and C5L2 indicates that

129 evel of post-translational modifications and subcellular distribution of CacyBP/SIP change after acti

130 Subcellular distribution of calmodulin (CaM) in human im

131 Subcellular distribution of Calmodulin (CaM) in human im

132 patterns are determined by variations in the subcellular distribution of calmodulin (CaM), indicating

133 Recent insights into the subcellular distribution of cardiac and neuronal NaV iso

134 y, mtv1 nev/agd5 double mutants show altered subcellular distribution of CCV cargo exported from the

135 In this study we investigated the subcellular distribution of Cd and Cp in the amygdala an

136 ysis revealed IR-induced phosphorylation and subcellular distribution of Chk2 phosphorylated species.

137 We further examined the subcellular distribution of CHT and observed that immuno

138 This pattern is consistent with the subcellular distribution of CHT displayed in other choli

139 echanism through which the expression and/or subcellular distribution of CK2 beta-subunits could part

140 we used Arabidopsis thaliana to examine the subcellular distribution of CL and CARDIOLIPIN SYNTHASE

141 form poised to provide new insights into the subcellular distribution of common H2S donors and a usef

142 ement of channels within a plaque determines subcellular distribution of connexin binding partners an

143 nuclear Ca(2+) signaling, we manipulated the subcellular distribution of CSQ2 by overexpression of CS

144 Subcellular distribution of CTCF and colocalization with

145 However, the subcellular distribution of CTLA-4 is unusual for a rece

146 ing new link to genetic variations affecting subcellular distribution of CYP2E1 with alcohol-induced

147 mRNA partitioning, we report an overlapping subcellular distribution of cytosolic/nucleoplasmic and

148 novel, long-lasting adaptive response in the subcellular distribution of D1 receptors, resulting in a

149 ion, and, in turn, altered expression and/or subcellular distribution of D2R in the PL.

150 V genotype in d3 lipid accumulation, and the subcellular distribution of d3.

151 Despite this differential subcellular distribution of DFF40/CAD, we find no differ

152 Arp2/3 affects the subcellular distribution of DLG-1 and ERM-1.

153 To map the cellular and subcellular distribution of DNase IIbeta activity in the

154 Instead, Ack is required for the subcellular distribution of Dock (dreadlocks), the Droso

155 R and to determine how agonists regulate the subcellular distribution of DOR.

156 By evaluating the subcellular distribution of each SecA, SecA1 was shown t

157 Furthermore, it suggests that the subcellular distribution of eIF4F components may potenti

158 In the present work, we show that subcellular distribution of eIF6 in the nuclei and the c

159 ents' primary fibroblasts exhibited abnormal subcellular distribution of endosomes marked by Rab5, Ra

160 propose from these new findings a model for subcellular distribution of enzymes that synthesize and

161 rhythmogenic, it is unknown whether distinct subcellular distribution of Epac1 vs. Epac2 contributes

162 ration over the wounded area by altering the subcellular distribution of F-actin.

163 on acts as a molecular switch to control the subcellular distribution of Fam13a.

164 We also obtained the subcellular distribution of fast and slow diffusing tRNA

165 Although glucose did not affect the subcellular distribution of FRQ in the WT, highly elevat

166 Here, we characterized the subcellular distribution of GABA(A)R subtypes in nocicep

167 Furthermore, the subcellular distribution of gamma-Tubulin and Cyclin B i

168 e demonstrate that the expression levels and subcellular distribution of giant obscurins are altered

169 f TTG1 and GL1 through mutation, affects the subcellular distribution of GL3.

170 that, in the absence of VAMP8, the relative subcellular distribution of GLUT4 is altered, resulting

171 ith O-glycosylation of GNAT1 and affects the subcellular distribution of GNAT1.

172 lls to osmotic stress induces changes in the subcellular distribution of Gpd1p to the cytosol and nuc

173 However, cellular expression and subcellular distribution of GRKs and arrestins in the br

174 These data demonstrate that the regional and subcellular distribution of HDAC4 is heterogeneous and r

175 The subcellular distribution of hippocampal CB1 receptors of

176 ic colocalization of Rab GTPases defined the subcellular distribution of Hyal1 as early and late endo

177 We determined the subcellular distribution of individual machines, the sto

178 The subcellular distribution of InsP3R isoforms may critical

179 It thus regulates the abundance and subcellular distribution of its cargo within cells.

180 nt modes of interaction, and thus affect the subcellular distribution of K-Ras4B in different ways.

181 The subcellular distribution of kinases and other signaling

182 We analyzed the subcellular distribution of Kv2.2 protein within single

183 s in midtransmigration, we could monitor the subcellular distribution of L-selectin and better unders

184 The broad subcellular distribution of LEA proteins highlights the

185 te Saccharomyces cerevisiae We find that the subcellular distribution of LH is heterogeneous; the cyt

186 Manipulation of the subcellular distribution of LIP1 revealed that the circa

187 For both types of responses, the subcellular distribution of loss in traction forces was

188 defects were associated with changes in the subcellular distribution of markers of epithelial cell p

189 Previous reports have suggested that the subcellular distribution of Merlin is critical to its fu

190 The subcellular distribution of Met was characterized using

191 They also highlight the fact that the subcellular distribution of mHTT is highly dynamic such

192 A activity and turnover can be controlled by subcellular distribution of miRNPs that may get differen

193 we propose a dynamic model that explains the subcellular distribution of misfolded proteins as a func

194 ations of mitochondrial dynamics altered the subcellular distribution of mitochondria in breast cance

195 ity, and directional migration, resulting in subcellular distribution of mitochondria to the peripher

196 insulin sensitivity are driven by changes in subcellular distribution of MKP7 and activated JNK.

197 GRK5 regulated the subcellular distribution of moesin and colocalized with

198 nal antibodies (mAb), and to investigate the subcellular distribution of mutant versus wild-type (WT)

199 We previously reported that the subcellular distribution of Na(+),K(+)-ATPase is modulat

200 groove of this PDZ domain and determine the subcellular distribution of neuronal NOS (nNOS).

201 protein controls biophysical properties and subcellular distribution of neuronal voltage-gated Na(+)

202 PY(GFP) transgenic mice, we have studied the subcellular distribution of neuropeptide Y (NPY), a prot

203 in the levels, subunit composition, or gross subcellular distribution of NMDARs.

204 NS5A inhibitors had no overall effect on the subcellular distribution of NS5A, but completely prevent

205 A replication, and its disruption alters the subcellular distribution of NS5A.

206 ication phenotype correlated with an altered subcellular distribution of NS5A.

207 In contrast to alterations in the subcellular distribution of nuclear factors observed dur

208 The subcellular distribution of p63RhoGEF(580) and p63RhoGEF

209 re, we report a novel method for imaging the subcellular distribution of palmitoylated forms of cellu

210 We therefore investigated the subcellular distribution of Panx1 in the mouse retina of

211 re nuclear proteins are degraded because the subcellular distribution of peptidase activity has not b

212 ine the mechanism by which Akt3 controls the subcellular distribution of PGC-1alpha and to explore th

213 ut that a striking variability exists in the subcellular distribution of phosphorylated receptors amo

214 by the distinctive substrate specificity and subcellular distribution of PKDs.

215 nohistochemistry to analyze the cellular and subcellular distribution of PMCA1a in the brain.

216 s Nrf2 activity by controlling abundance and subcellular distribution of PML and that PML is essentia

217 Knowledge of the subcellular distribution of proteins is vital for unders

218 cent microscopy (IFM) showed a change in the subcellular distribution of RHA from the nucleus to the

219 y of the hairpin region is important for the subcellular distribution of RHD3, and that reduced avail

220 t a second role of Y RNAs is to regulate the subcellular distribution of Ro.

221 cular transport are critical for an adequate subcellular distribution of S-acylated Ras proteins.

222 ayed to ATP7A, we examined the abundance and subcellular distribution of several soluble COX assembly

223 demonstrated both reduced levels and altered subcellular distribution of STREX-containing BKCa channe

224 The subcellular distribution of synapses is fundamentally im

225 report that dap160 overexpression alters the subcellular distribution of synaptojanin, and overexpres

226 In cells lacking steryl esters, the subcellular distribution of Tgl4p and Tgl5p is unaffecte

227 To investigate the subcellular distribution of the beta subunits we have ut

228 Ialpha depletions altered the content and/or subcellular distribution of the BLOC-1-sensitive cargoes

229 r basis of this process, we investigated the subcellular distribution of the cathepsin B precursor, p

230 i responses to flow but markedly shifted the subcellular distribution of the channel toward the apica

231 Hence, perturbing the subcellular distribution of the chelator nicotianamine h

232 e residues within the NES disrupt the normal subcellular distribution of the full-length CIITA, impai

233 The subcellular distribution of the G protein-coupled recept

234 s fused to localization domains to alter the subcellular distribution of the GFP-tagged mRNA or prote

235 First, ARF6 regulates the subcellular distribution of the GTPase, Rac1, to tubule

236 DNA into patient's fibroblasts corrected the subcellular distribution of the lysosomes, supporting th

237 these mice left open questions regarding the subcellular distribution of the mutant protein and the n

238 The subcellular distribution of the oligonucleotide delivere

239 microscopy was used to determine whether the subcellular distribution of the organizer/adapter NOX p4

240 We found that subcellular distribution of the p57kip2 protein changed

241 methionine at position 148 did not alter the subcellular distribution of the protein.

242 of IRES activation, although the levels and subcellular distribution of the proteins were unchanged.

243 Both cellular uptake and subcellular distribution of the PSs were affected by the

244 tors without relying on large changes in the subcellular distribution of the receptor.

245 In NPCs, Pml regulated the subcellular distribution of the retinoblastoma protein (

246 ed between eIF2alpha phosphorylation and the subcellular distribution of the RNA-binding protein hete

247 hus, findings suggest that selection for the subcellular distribution of the SEN complex may reside n

248 the selectivity of drug actions based on the subcellular distribution of their targets.

249 adipocytes, but differentially regulates the subcellular distribution of these Akt isoforms.

250 An altered subcellular distribution of these ligands is found in mu

251 ts have uncovered a relationship between the subcellular distribution of these metalloinsertors and t

252 Here we discuss the nature and subcellular distribution of these posttranslational mark

253 ovessels of S1pr1(iECKO) mice showed altered subcellular distribution of tight junctional proteins.

254 omer-Golgi plasmids and used to identify the subcellular distribution of TLR4 before and after LPS st

255 Moreover, on the basis of the subcellular distribution of TOC1 small RNAs and target t

256 Of particular interest, the subcellular distribution of TP-modified ODNs is highly d

257 ainst TRPML3 to determine the expression and subcellular distribution of TRPML3 in the inner ear as w

258 Ca(2+) signaling as well as the function and subcellular distribution of TRPV4.

259 +)]i responses to flow without affecting the subcellular distribution of TRPV4.

260 copy and transgenesis were used to study the subcellular distribution of xlProminin-1.

261 ation signal, and although we found that the subcellular distribution of Xrcc3 was not significantly

262 In this study, the cellular and subcellular distributions of As and silicon (Si) in rice

263 However, the subcellular distributions of DLG1 and LIN7C are independ

264 We found that the subcellular distributions of fluorescent protein-tagged

265 m IL-33-producing cells or by differences in subcellular distributions of IL-33 isoforms.

266 Glucose availability regulates the subcellular distributions of karyopherins likely due to

267 Subcellular distributions of Msn5 and Los1 are altered u

268 treated mice were perfused in vitro, and the subcellular distributions of pendrin and the H(+)-ATPase

269 s, with particular relevance for probing the subcellular distributions of small molecules, such as dr

270 optimized for detection of the cellular and subcellular distributions of specific mRNA within Drosop

271 functions directly result from the distinct subcellular distributions of the two Rnd proteins.

272 The cellular and subcellular distributions of trace elements can provide

273 oping axons, yet little is known about their subcellular distribution or, specifically, which transcr

274 The properties and subcellular distribution pattern of HCN channels are the

275 The subcellular distribution pattern of the HCN channels inf

276 in DLBCLs resulting from differences in the subcellular distribution pattern.

277 t, side-view shear strains exhibited similar subcellular distribution patterns in both networks.

278 These subcellular distribution patterns were recapitulated in

279 differentially expressed and have different subcellular distribution patterns.

280 Based on the biochemical and subcellular distribution properties of U1-70K in AD, we

281 cally active new Kdm3a isoform and show that subcellular distribution, protein levels, and lysine dem

282 we document the influence of Parkin on Pink1 subcellular distribution, providing further evidence for

283 the actin cytoskeleton, markedly alters Gag subcellular distribution, relocates sites of assembly, a

284 This was accompanied by changes in PP2A subcellular distribution resulting in increased physical

285 Subsequent determination of silver subcellular distribution revealed that significantly mor

286 sponse to anaerobiosis by regulating RNase E subcellular distribution, RNase E enzymatic activity, an

287 ing their study, lncRNAs have widely varying subcellular distributions: some reside predominantly in

288 Subcellular distribution studies demonstrate that endogl

289 tes provide singular information about H-Ras subcellular distribution that is required for GTPase sig

290 Subcellular distribution, tissue-specific expression, su

291 us effect on the growth-supporting activity, subcellular distribution, tRNA binding, or interactions

292 nd that all tested karyopherins invert their subcellular distributions upon glucose deprivation but n

293 GABAAR complexes that explain GABAAR subunit subcellular distributions using mice and Xenopus laevis

294 icity, and glutamate receptor expression and subcellular distribution were measured at P60.

295 Hexokinase activity and subcellular distribution were not significantly differen

296 mutants of H-Ras differed not only in their subcellular distribution, where both proteins localized

297 Proteins exhibit complex subcellular distributions, which may include localizing

298 ating that our methods can unmix the complex subcellular distribution with reasonably high accuracy.

299 ngly, the pUL136 isoforms exhibited distinct subcellular distributions with varying association with

300 ctional proteins translates to heterogeneous subcellular distribution within a cardiac myocyte.