ライフサイエンスコーパス: subcellular localization

1 types of ion channel expressed and on their subcellular localization.

2 able to zoom-in to show distinct patterns of subcellular localization.

3 sary for the light-controlled change in COP1 subcellular localization.

4 d protein-membrane interactions, and protein subcellular localization.

5 n osteosarcoma cases exhibiting aberrant p27 subcellular localization.

6 y, which play essential roles in determining subcellular localization.

7 not regulate total MCM3 protein stability or subcellular localization.

8 imilar binding to BRI1 and BZR1 but distinct subcellular localization.

9 observed regardless of the target protein's subcellular localization.

10 fications that can modulate htt toxicity and subcellular localization.

11 uired the presence of P2X2R for their proper subcellular localization.

12 mEN), for large-scale predictions of protein subcellular localization.

13 rmation regarding both protein abundance and subcellular localization.

14 tability, catalytic activity, and/or altered subcellular localization.

15 cell size, terminal morphology, and protein subcellular localization.

16 nships in eukaryotic systems, independent of subcellular localization.

17 cysteines and promotes membrane binding and subcellular localization.

18 ymes display a conserved structural fold and subcellular localization.

19 brain reveal an exquisite refinement of KCh subcellular localization.

20 affect receptor sensitivity without changing subcellular localization.

21 unity and to regulate their own activity and subcellular localization.

22 Cdc14 that, in turn, is able to control its subcellular localization.

23 th the Atg8 homolog GABARAP and regulate its subcellular localization.

24 ng the GAP activity and/or the WPP-dependent subcellular localization.

25 ive kinases that are regulated through their subcellular localization.

26 particular the establishment of their polar subcellular localization.

27 is oocytes, and their in planta cellular and subcellular localization.

28 ut ligand activation, effector coupling, and subcellular localization.

29 igase activity, substrate specification, and subcellular localization.

30 aying altered lipid phosphatase function and subcellular localization.

31 fast and effective method to annotate their subcellular localization.

32 with unique target sequence specificity and subcellular localization.

33 respectively, enforced through differential subcellular localization.

34 conformational flexibility or changing their subcellular localization.

35 hat the DLL4 ICD is required for normal DLL4 subcellular localization.

36 and directing their efficient expression and subcellular localization.

37 s and cellular processes, and showed diverse subcellular localizations.

38 xin transport on account of their asymmetric subcellular localizations.

39 omprehensive hierarchical structure of >1600 subcellular localizations.

40 underlying mechanism is an ambiguity of S1R subcellular localizations.

41 in various isoforms with distinct tissue and subcellular localizations.

42 d that the resulting isoforms have different subcellular localizations.

43 ired PTEN function through alteration of its subcellular localization accompanied by resistance to ap

44 ly characterized these AR-Vs regarding their subcellular localization, affinity for HSP90 and transac

45 Quantitative subcellular localization analysis revealed that PA-X was

46 Subcellular localization analysis showed that MYBS1 and

47 elements of functional context: (i) protein subcellular localization and (ii) protein-protein intera

48 Together, our results unravel differences in subcellular localization and ability to bind mouse eryth

49 ates canonical Wnt signaling by altering the subcellular localization and availability of beta-cateni

50 contact-dependent transcriptional reporters, subcellular localization and bacterial two hybrid assays

51 P) affects the biology of APP, including its subcellular localization and cell surface expression, it

52 ripts, far fewer have been characterized for subcellular localization and cell-to-cell variability.

53 We found that O2 levels regulate the subcellular localization and channel activity of the pol

54 unctions as an oncoprotein by regulating the subcellular localization and degradation of p27(KIP1).

55 zed the structure of human COQ2, defined its subcellular localization and developed a yeast model to

56 tudied extensively, the contributions of the subcellular localization and dynamics of the active PEPR

57 ents and that this interaction regulates its subcellular localization and enhances its effect on VASP

58 le, we demonstrate in human T cells that the subcellular localization and function of the protein tyr

59 lysine methyltransferase SETD7 controls its subcellular localization and function.

60 Together, the subcellular localization and functional characterization

61 ultiple stoichiometries exhibiting different subcellular localization and functional properties.

62 Here, we report the expression, subcellular localization and functions of Kif2a during m

63 ipates in diverse processes depending on its subcellular localization and interactome.

64 ts ability to interact with Rab11 modify Lck subcellular localization and its delivery to the immunol

65 gate its mechanism of action, we studied its subcellular localization and its interaction with member

66 In cultured astrocytes, differences in the subcellular localization and macromolecular interactions

67 sms of AMPK regulation, including changes in subcellular localization and phosphorylation by non-cano

68 dy was to determine insulin's effects on the subcellular localization and phosphorylation of AKT1, AK

69 Rac1 and Cdc42 signaling by controlling the subcellular localization and phosphorylation status of R

70 PH-domain mutants alter subcellular localization and result in decreased interac

71 ial fission disrupted both the age-dependent subcellular localization and segregation of mitochondria

72 hway promotes Hh signaling by regulating Smo subcellular localization and shed light on how sumoylati

73 unctional importance in protein degradation, subcellular localization and signal transduction pathway

74 Advanced technologies of lncRNA subcellular localization and silencing were used to iden

75 Because the subcellular localization and substrate specificity of th

76 when transport factor bound and rescues the subcellular localization and synthetic sickness of Heh2D

77 and modifier Tet1 by analyzing their dynamic subcellular localization and the formation of the Tet ox

78 n channels depends critically on the precise subcellular localization and the number of channel prote

79 n channels depends critically on the precise subcellular localization and the number of channel prote

80 lar targeting by the LKB1 complex depends on subcellular localization and transcriptional expression.

81 hagy, RPS6KB1-VMP1 fusion exhibited aberrant subcellular localization and was relatively ineffective

82 The lysosomes were found to be the site of subcellular localization and were consequently the prima

83 abietane olefin miltiradiene, but also their subcellular localization and, critically, genetic analys

84 In the study, we investigated subcellular localizations and assembly-promoting functio

85 homo- and heterodimers of ZnTs with distinct subcellular localizations and function, hence highlighti

86 omPPI provides confidence scores for protein subcellular localizations and protein-protein interactio

87 the two interacting proteins have no common subcellular localizations and to predict novel propertie

88 re required for light-responsiveness of COP1 subcellular localization, and (2) they promote COP1 acti

89 ch protein is calculated to quantify protein subcellular localization, and 84% accuracy is achieved c

90 e products differ in their expression level, subcellular localization, and activity.

91 ry mechanism underlying BRCC36 DUB activity, subcellular localization, and biological function.

92 lar cloning to examine how PTEN's stability, subcellular localization, and catalytic activity affect

93 twork-based analyses of domain associations, subcellular localization, and co-complex formation.

94 re uncovered the heterodimerization, altered subcellular localization, and function of multiple ZnTs

95 f HBx by HDM2 which regulates its stability, subcellular localization, and functions.

96 require accurate cell phenotype recognition, subcellular localization, and histopathological classifi

97 on of the protein's domains to its function, subcellular localization, and interaction with itself an

98 ctly found the overlap of markers with known subcellular localization, and it performed better than a

99 ategies to investigate C9orf72 interactions, subcellular localization, and knockout (KO) phenotypes.

100 -binding proteins, resulting in differential subcellular localization, and offers new therapeutic opp

101 n, enhanced proteasomal degradation, altered subcellular localization, and reduced responsiveness to

102 lar processes including signal transduction, subcellular localization, and regulation of enzymatic ac

103 ritical role in regulating its stability and subcellular localization, and thereby its function.

104 rences in channel permeability, selectivity, subcellular localization, and trafficking responses have

105 ERalpha protein levels, subcellular localization, and transcriptional function w

106 , we demonstrate that ECD protein levels and subcellular localization are invariant during cell cycle

107 channels, the mechanisms that mediate their subcellular localization are largely unknown.

108 ial of histone deacetylase 1 (HDAC1) and its subcellular localization are not fully understood.

109 ccessory domains regulate properties such as subcellular localization, as exemplified by a ubiquitin-

110 cytoskeleton-mediated regulation of Yki/YAP subcellular localization, as well as YAP cytoplasmic tra

111 Subcellular localization assays revealed that HaEXPB2 co

112 ough these motifs do not affect the receptor subcellular localization at 37 degrees C, deletion of th

113 ed information on tissue expression, protein subcellular localization, biological process, and molecu

114 Mutant GARS proteins display normal subcellular localization but markedly reduce global prot

115 ing chromosome segregation, and controls its subcellular localization but not protein levels.

116 gh alteration of their expression levels and subcellular localization but only minimally by altered R

117 of endothelial NO synthase and modulates its subcellular localization, but the role of NOSTRIN in pat

118 of Clcn3 results in proteins with different subcellular localizations, but leaves the transport func

119 that Ser-31 phosphorylation may regulate TH subcellular localization by enabling its transport along

120 for biochemical analysis, and determine its subcellular localization by fluorescence microscopy.

121 r controlled knockdown and show that similar subcellular localization can predict redundant functions

122 transport, affects amyloid precursor protein subcellular localization, cell-surface expression, as we

123 mbrane anchors of Bax and Bak reverses their subcellular localization compared to the wild-type prote

124 Subcellular localization critically influences protein f

125 oteomes, organelle-specific interactomes and subcellular localization data are available on its websi

126 f nine protein-protein interaction and eight subcellular localization data sets had four curation ste

127 at the mutations abrogate DNA binding, alter subcellular localization, decrease transcriptional repre

128 pal neuron axon growth and regeneration in a subcellular localization-dependent manner.

129 used a quantitative approach to study FP25K subcellular localization during infection using an AcMNP

130 tion into arrays modifies its own and ParC's subcellular localization dynamics, promoting their polar

131 Thus, dynamic subcellular localization emerges as a critical factor in

132 linkage between genomic position of ALEs and subcellular localization enables coordinated induction o

133 that full-length BACE1, independently of its subcellular localization, exists as trimers in human cel

134 cells as models that this variant disturbed subcellular localization, expression and solubility of P

135 the receptor in specific conformation and/or subcellular localization for different periods of time,

136 provides a promising strategy for directing subcellular localization for therapeutic and fundamental

137 abidopsis using protein-protein interaction, subcellular localization, gene knockout, and bioinformat

138 these subclasses hundreds of proteins whose subcellular localization had not previously been well de

139 ough many web-servers for predicting protein subcellular localization have been developed, they often

140 l PER, TIM, and CLK levels, activity, and/or subcellular localization have been identified, less is k

141 ith NuRD complex and the regulation of CASZ1 subcellular localization have not been characterized.

142 for which multiple functional properties and subcellular localizations have been reported.

143 Here, we describe how MAVS subcellular localization impacts its function and the re

144 mic factors, whereas disruption of this dual subcellular localization impairs CIITA functioning and e

145 However, its differential subcellular localization in different brain nuclei sugge

146 utility of the switch through light-mediated subcellular localization in mammalian cell culture and r

147 We performed an analysis of LFG subcellular localization in murine cortical neurons and

148 ate that the structural MAP tau modulates EB subcellular localization in neurons.

149 mination of molecular binding activities and subcellular localization in non-neuronal and neuronal ce

150 Subcellular localization in planta indicated that AtPyrP

151 osomal loci, determined their expression and subcellular localization in six tissues comprising 23 ce

152 l, little is known about AKT1, AKT2 or AS160 subcellular localization in skeletal muscle.

153 the importance of CORO1A oligomerization and subcellular localization in T-cell homeostasis.

154 Muller glia, but have different patterns of subcellular localization in the different species of rep

155 ive reducing substrates, we searched for its subcellular localization in the infective parasite stage

156 files, region-specific changes, and distinct subcellular localizations in ALS tissues.

157 Subcellular localization indicated that the EMB14 is tar

158 euronal morphology and express proteins with subcellular localization indicative of mature neurons.

159 Experiments show that subcellular localization information is promising in boo

160 the C-terminus of ATP8A2 in its expression, subcellular localization, interaction with its subunit C

161 This subcellular localization is diminished upon deletion of

162 Protein subcellular localization is fundamental to the establish

163 Predicting protein subcellular localization is indispensable for inferring

164 beta1-C121W subcellular localization is restricted to neuronal cell

165 rin Fat depends on its ability to change the subcellular localization, levels and activity of the unc

166 Consistent with its subcellular localization, loss of ANK results in reduced

167 ption, and suggests that regulation of CASZ1 subcellular localization may impact its function in norm

168 Direct perturbation of HIV-1 mRNA subcellular localization may represent a novel antiviral

169 We also putatively annotated and mapped the subcellular localization of 29 sulfoglycosphingolipids a

170 the effects of 48 chemical compounds on the subcellular localization of 48 proteins while performing

171 Immunofluorescence studies revealed that the subcellular localization of AC differs between melanocyt

172 intercellular contacts together control the subcellular localization of activated Notch1 and myocard

173 liferation and tumorigenesis by altering the subcellular localization of an essential YAP co-factor.

174 Subcellular localization of antigen, HLA molecules, and

175 Here, we explored the expression and subcellular localization of Arabidopsis thaliana DCL4.

176 COG null cells possess altered content and subcellular localization of ATP7A and CTR1 (SLC31A1), th

177 Reliable methods to determine the subcellular localization of bacterial proteins are neede

178 ence imaging to explore the biosynthesis and subcellular localization of beta-carboxysomes within a m

179 n, suggesting that 14-3-3sigma regulates the subcellular localization of c-Jun.

180 sed; 3) does not alter the protein levels or subcellular localization of CAR; 4) increases corepresso

181 immunofluorescence was used to identify the subcellular localization of CFTR in airway smooth muscle

182 eocytoplasmic partitioning, we monitored the subcellular localization of COP1 in a spa1234 quadruple

183 synchronization indicated that the shift in subcellular localization of E2(Y131A) occurred in mid-S

184 The subcellular localization of eIF4E closely correlates wit

185 d high-throughput method to identify precise subcellular localization of endogenous proteins is essen

186 ovides a high-throughput platform to map the subcellular localization of endogenous proteins with the

187 he PM and demonstrate that impbeta1 controls subcellular localization of Epac1.

188 One such question is the subcellular localization of ERManI, which has been sugge

189 ides on the endosperm/scutellum boundary and subcellular localization of ferulate in the aleurone.

190 Subcellular localization of FKBP10 was assessed by immun

191 Analysing the subcellular localization of four TbORC1/CDC6-interacting

192 Examination of subcellular localization of FOXO protein via CRISPR-assi

193 These patterns are determined by the subcellular localization of FUS, regardless of wild-type

194 the cytoplasm, it raises questions about the subcellular localization of glycosylated lignin oligomer

195 Salt inducible kinases (SIKs) control subcellular localization of HDAC4/5 and CRTC2.

196 Here we studied the subcellular localization of human ClC-4 in heterologous

197 ylinositol (4,5)-bisphosphate or altered the subcellular localization of INPP5K.

198 GTP/Ran*GDP gradient created by the distinct subcellular localization of its regulators RCC1 and RanG

199 re used to assess the molecular identity and subcellular localization of Kir channel isoforms.

200 When analyzing the subcellular localization of LmPRL-1 in promastigotes, am

201 alance between Rab7 and Arl8b determines the subcellular localization of lysosomes; more peripheral l

202 and prolyl hydroxylase egl-9, with impaired subcellular localization of Mint orthologue LIN-10, inte

203 Consistent with the subcellular localization of Mst, the intestinal defects

204 epidermis, Sdt is essential for the correct subcellular localization of PATJ in differentiated epith

205 However, the mechanisms controlling the subcellular localization of PC1 and PC2 are poorly under

206 ctional signaling is determined by the polar subcellular localization of PIN-FORMED (PIN) auxin trans

207 ponse, directly regulated the expression and subcellular localization of Pitx2.

208 ation of BRI1, but also demonstrate that the subcellular localization of PP2A specifies its substrate

209 f phospholipids and the C-terminal domain in subcellular localization of ProP were explored.

210 ide fully recapitulated their effects on the subcellular localization of ProP.

211 widely used as protein tags for studying the subcellular localization of proteins in plants.

212 methylation maintenance, likely by directing subcellular localization of proteins involved in this pr

213 d from the chorion and alters expression and subcellular localization of proteins required for cell c

214 Subcellular localization of PS-/SYS-GFP was observed usi

215 corrected stability, enzymatic activity, and subcellular localization of R91W RPE65, which was also a

216 dissect whether the GAP activity and/or the subcellular localization of RanGAP are responsible for t

217 regulate both HCV genome replication and the subcellular localization of replication complexes.IMPORT

218 om uses a conserved SD2 domain to direct the subcellular localization of Rho-associated kinase (Rock)

219 Subcellular localization of ribosomes defines the locati

220 platform for in vivo or in vitro analysis of subcellular localization of rice proteins.

221 lying the establishment of neuronal polarity.Subcellular localization of RNAs and proteins is importa

222 The expression and subcellular localization of Set-beta are altered in Alzh

223 etion of hormogonium polysaccharide, and the subcellular localization of several Pil proteins in moti

224 this study, we show that the expression and subcellular localization of Shh effectors and ciliary pr

225 rmation for both predicting and interpreting subcellular localization of single- and multi-location p

226 The distribution and subcellular localization of Slick and Slack channels in

227 tubule number and length correlated with the subcellular localization of SPBs rather than their age.

228 e NAc with associated changes in the nuclear subcellular localization of SRF and MAL.

229 lysis and confocal microscopy visualized the subcellular localization of T-bet and GATA-3.

230 gues and variants in vitro was compared with subcellular localization of the corresponding orthologue

231 An analysis of the subcellular localization of the DHARs in Arabidopsis lin

232 is elegans, revealing dynamic changes in the subcellular localization of the EFF-1 fusogen after axot

233 aling is often achieved through differential subcellular localization of the enzyme by interaction wi

234 These data, combined to the subcellular localization of the enzymes, allowed us to p

235 The subcellular localization of the fluorescently labeled me

236 can produce SPMs and assessed expression and subcellular localization of the key SPM biosynthetic enz

237 activity is unclear, it is evident that the subcellular localization of the protein is important for

238 gs using a specific OR51E2 antibody revealed subcellular localization of the receptor in early endoso

239 Notch activity regulates subcellular localization of the Shh receptor Patched1, g

240 of cIAP1 and cIAP2 and observe differential subcellular localization of the two proteins in OSCC.

241 he Drosophila wing primordium typically show subcellular localization of the unconventional myosin Da

242 the cellular expression of ZmSut1 RNA or the subcellular localization of the ZmSUT1 protein to assess

243 lihood of their interactions considering the subcellular localization of their interacting partners.

244 d by Nature Protocols in 2006) to enable the subcellular localization of thousands of proteins per ex

245 The subcellular localization of TIP39 in keratinocytes chang

246 sport, a process that determines the precise subcellular localization of translation products within

247 By analyzing the subcellular localization of truncated versions of p190A

248 biquitination controls protein stability and subcellular localization of tyrosine kinase receptors, h

249 SNAP-47 silencing further shifted the subcellular localization of VAMP4 from the Golgi apparat

250 ies, pattern of viral protein synthesis, and subcellular localization of viral N and NSs proteins of

251 ics, the development of detailed maps of the subcellular localization of viral replication complexes

252 The subcellular localization of VirG and VirA proteins trans

253 ally indispensable for cytoskeleton-mediated subcellular localization of Yki.

254 ce lifetime (taum ) correlated with distinct subcellular localizations of anthocyanins.

255 used to determine the expression levels and subcellular localizations of C9-L and C9-S.

256 h dystrophin into ten fragments and examined subcellular localizations of each fragment by adeno-asso

257 tivity that is not achieved via altering its subcellular localization or affinity for membranes but r

258 tion of R-Ras proteins does not affect their subcellular localization or stability but rather stimula

259 ation in parasitic strategies (e.g. host and subcellular localization) or due to multiple transitions

260 ipids to regulate their activity, stability, subcellular localization, or macromolecular interactions

261 By integrating the information of subcellular localization, orthologous proteins and PPI n

262 rate that, by integrating the information of subcellular localization, orthologous proteins with PPI

263 copy on a genome-wide scale to determine the subcellular localization pattern of yeast Pex11 in all n

264 Remarkably, beta-catenin showed a reversed subcellular localization pattern: Although beta-catenin

265 o systematically quantify and categorize the subcellular localization patterns of a representative se

266 ) in hair cells were produced to examine the subcellular localization patterns of wild-type and mutan

267 image-based dataset, we observe a variety of subcellular localization patterns, ranging from bright s

268 Sannerud et al. now show that regulation of subcellular localization plays a central role, advancing

269 that FUEL-mLoc outperforms state-of-the-art subcellular-localization predictors.

270 dative ability that correlates with lysosome subcellular localization, raising questions about the fu

271 After gene duplication, changes in subcellular localization relative to the ancestral house

272 of mRNA transcripts, protein expression, and subcellular localization revealed that KV1.5 is the majo

273 -S) initiating from codon 16 that displays a subcellular localization similar to that of pUL138-L.

274 n platform (HSN2-BG) that is compatible with subcellular localization SNAP-tag fusion protein methodo

275 Subcellular localization studies have shown that TILs ar

276 n human coronary artery disease lesions, and subcellular localization studies in cultured vascular sm

277 -dimensional protein structure and performed subcellular localization studies.

278 Subcellular localization study indicated that it is an i

279 In a previous subcellular localization study of hydrogen peroxide-resp

280 tein exhibits reduced expression and altered subcellular localization, suggesting the protective mech

281 Subcellular localization terms are obtained from public

282 ight-dependent protein isoforms with altered subcellular localization that help the plant respond met

283 SK channels show a distinct subcellular localization that is crucial for their neuro

284 eceptor-mediated endocytosis and appropriate subcellular localization, the identity of the cell surfa

285 options for individual proteins giving their subcellular localization, their interactions and the lik

286 ional methods exist to predict plant protein subcellular localization, they perform poorly for effect

287 eins and RNAs are tightly regulated in their subcellular localization to exert their local function.

288 mechanism whereby Hh induces a change in Smo subcellular localization to promote its association with

289 Reticulon-1 subcellular localization to the periphery after exposure

290 Subcellular localization to the tonoplast, complementati

291 accumulated throughout the infection with a subcellular localization typical of the endoplasmic reti

292 Cytotoxicity and subcellular localization was studied in human fibroblast

293 To visualize mensacarcin's subcellular localization, we synthesized a fluorescent m

294 These changes in CLU subcellular localization were also associated with Bax a

295 tion of the gene, its expression pattern and subcellular localization were characterized.

296 The amino acid residues modulating HDAC1 subcellular localization were identified by site-directe

297 escent foci and organelles, determines their subcellular localization with subpixel resolution, and t

298 itored EV proteins, but they differ in their subcellular localization, with CD63 primarily in endosom

299 iral envelope glycoproteins as well as IFITM subcellular localization within the target cell.

300 K is a potent MT depolymerase with a complex subcellular localization, yet how MCAK spatial regulatio