ライフサイエンスコーパス: subcellular location

1 is regulated in large part by control of its subcellular location.

2 unique functions of Agap2 determined by its subcellular location.

3 unction of some enzymes is governed by their subcellular location.

4 ent properties to simulate mixed patterns of subcellular location.

5 ive abundance of these PTMs as a function of subcellular location.

6 e effects of mild oxidative injury vary with subcellular location.

7 ocesses in which they play a role, and their subcellular location.

8 question of how PTPMEG2 is targeted to this subcellular location.

9 we investigated its tissue distribution and subcellular location.

10 nteraction module to dock CikA at a specific subcellular location.

11 ryl hydrocarbon receptor (AHR) stability and subcellular location.

12 ryl hydrocarbon receptor (AHR) stability and subcellular location.

13 thesis of holdfasts and pili at their proper subcellular location.

14 ncluding it is the major or only Grx in this subcellular location.

15 is of protein-protein interactions and their subcellular location.

16 n of different GTPase effectors in different subcellular locations.

17 um/calmodulin kinase II isoforms to specific subcellular locations.

18 s dynamic clusters at both polar and lateral subcellular locations.

19 striction of signaling complexes to discreet subcellular locations.

20 d with each other, but are found in distinct subcellular locations.

21 ocalization to and delocalization from these subcellular locations.

22 different sets of intermediates at different subcellular locations.

23 nct ubiquitin E3 ligase complex at different subcellular locations.

24 nstructed two more datasets of nine and five subcellular locations.

25 independent of each other, to their separate subcellular locations.

26 can be differentially regulated at different subcellular locations.

27 egmented them into 12 classes based on their subcellular locations.

28 rt and delivery of selected MBOs to discrete subcellular locations.

29 several ATP-fueled proteases occupy distinct subcellular locations.

30 pport the interaction with RNAs in different subcellular locations.

31 t at, or move between, two or more different subcellular locations.

32 ls to nucleus and becomes dispersed in other subcellular locations.

33 support interactions with RNAs in different subcellular locations.

34 ific protein functional domains in different subcellular locations.

35 de channel/transporter family have different subcellular locations.

36 n be activated by growth factors at distinct subcellular locations.

37 d compositional differences across different subcellular locations.

38 atures, protein aggregates form in different subcellular locations.

39 teins (AKAPs) bind and target PKA to various subcellular locations.

40 MP-dependence and localizing PKA to specific subcellular locations.

41 cycle, the two origins localized to distinct subcellular locations.

42 oring proteins (AKAPs) tether PKA to various subcellular locations.

43 ctional domains, or by acquiring alternative subcellular locations.

44 athways that shape APA profiles in different subcellular locations.

45 dy-state dynamics of proteins and unexpected subcellular locations.

46 the local interaction network organized into subcellular locations.

47 amics of eisosome core proteins at different subcellular locations.

48 aling pathway can be activated from multiple subcellular locations.

49 es global analysis of translation in defined subcellular locations.

50 ave different tissue expression patterns and subcellular locations.

51 ular motors transport organelles to specific subcellular locations.

52 o transport diverse cargo to the appropriate subcellular locations.

53 chinery to express and transport proteins to subcellular locations.

54 ish receptor-mediated signaling at different subcellular locations, a phenomenon known as spatial sen

55 a complex array of proteins modulating their subcellular location and activity.

56 found in homogenized plant tissues, but its subcellular location and availability to plant microbes

57 with a role in pH homeostasis, though their subcellular location and biological roles in plants are

58 While much is known about the subcellular location and biophysical properties of condu

59 Their specific subcellular location and differential expression pattern

60 were used to examine the effects of antigen subcellular location and expression level on the develop

61 ctive molecular hierarchy depending on their subcellular location and extracellular stimuli.

62 -terminal sequence elements that promote Chp subcellular location and function expand the complexity

63 The subcellular location and function of one of these member

64 However, little is known regarding the subcellular location and function of the majority of the

65 n Cdc42, suggesting potential differences in subcellular location and function.

66 xpressed the PPE proteins can alter both the subcellular location and level of accumulation of the up

67 We investigated the subcellular location and myristoylation of AtCPK5, a mem

68 n and dephosphorylation of Pah1 regulate its subcellular location and phosphatidate phosphatase activ

69 -Pick C1, was characterized to determine its subcellular location and potential function(s).

70 e interaction of PKA with AKAPs disrupts its subcellular location and prevents LTP in the hippocampus

71 This study examines the subcellular location and relationship with prognostic fa

72 resent studies were undertaken to define the subcellular location and role of RyR in the control of s

73 fusion expression can have a bold effect on subcellular location and that chromosomal, intraoperon e

74 ulation of molecules within neurons, but the subcellular location and the cellular impact are often u

75 important mechanism for regulating both the subcellular location and the function of proteins.

76 li K-12 as well as information regarding its subcellular location and the genetic loci involved in it

77 To investigate the subcellular location and the mechanism of ecto-nucleotid

78 en observed to localize to several different subcellular locations and cellular redox conditions vary

79 ly of dozens of heterotrimers with different subcellular locations and cellular substrates dictated b

80 The apparatus assembled in discrete subcellular locations and exported Hcp1, a hexameric pro

81 f CAAX signal modifications in dictating the subcellular locations and functions of the Rho GTPase fa

82 2 PDI genes, but little is known about their subcellular locations and functions.

83 between many types of proteins in different subcellular locations and in different cell types and or

84 essed protein displays at least two distinct subcellular locations and related functions.

85 ding proteins that it predicts share similar subcellular locations and residue charge profiles with t

86 oach to determine Cdc42 activity at specific subcellular locations and reveals new regulatory princip

87 The distinct subcellular locations and the differences between the ef

88 l proteins appear more frequently in certain subcellular locations and their evolution more conservat

89 peptides from source proteins of almost all subcellular locations and were involved in various cellu

90 t particular Gbetagamma subunits to specific subcellular locations and/or macromolecular complexes in

91 en identified that direct PP1 to a number of subcellular locations and/or substrates, no targeting su

92 molecules and its implication for function, subcellular location, and half-life of proteins.

93 ttern of the dibenzylcyclooctynes influences subcellular location, and in particular it has been show

94 otential varies, depending on energy demand, subcellular location, and morphology and is commonly use

95 cycle stage at which proteins are expressed, subcellular location, and other proteomic features.

96 ntly more likely to be found within the same subcellular location, and significantly less likely to b

97 protomers are too weak to directly influence subcellular location, and that mechanisms that move thes

98 osphorylation, protein-protein interactions, subcellular location, and/or turnover of certain phospho

99 ation of a query protein among many possible subcellular locations, and (2) how to deal with the case

100 lipoprotein that is able to occupy distinct subcellular locations, and challenges models in which th

101 r regulation, establish their biogenesis and subcellular locations, and explore their functionality.

102 ich engulf portions of cytoplasm at specific subcellular locations, and their subsequent maturation i

103 ctors of survival and death are in different subcellular locations, and thus depend on the spatial ch

104 to modulate betagamma signaling at specific subcellular locations, and we demonstrate novel cargo se

105 eening suffer significantly from the lack of subcellular location annotations for bioimages from canc

106 tissues; however, ALF4 expression and ALF4's subcellular location are not regulated by auxin.

107 attachment to membranes and rafts, and their subcellular locations are poorly understood; live prion

108 specificity of sgk1 function; however, which subcellular locations are required for sgk1-regulated EN

109 in to promote protein associations or direct subcellular location, as seen in other UBA-containing pr

110 t to target and traffic channels to specific subcellular locations, as well as anchor and stabilize c

111 ation of ETR2 does not require exit from its subcellular location at the endoplasmic reticulum.

112 The subcellular location at which genomic RNA is packaged by

113 t is highly desirable to predict a protein's subcellular locations automatically from its sequence.

114 SVM modules were trained to predict the subcellular location based on amino acid composition and

115 rial biology in endothelial cells, including subcellular location, biogenesis, dynamics, autophagy, r

116 of the type IV apparatus, we determined its subcellular location by immunofluorescence microscopy.

117 roteins can be positioned rapidly at precise subcellular locations by local protein synthesis (LPS) t

118 es these excitotoxic Tat effects at the same subcellular locations by mobilizing additional [Ca(2+)]i

119 cytometric analysis of cells and proteins in subcellular locations by use of multiplexed antibody sta

120 llows the targeting of proteins to different subcellular locations by use of nanobody-fusion proteins

121 se proteins were classified into 22 distinct subcellular location categories by visual examination.

122 ng of Gbetagamma to the Golgi, but not other subcellular locations, causes phospholipase C- and prote

123 We validate our framework on protein subcellular location classification, and show that the c

124 ructural evidence that in the VTA, M5R has a subcellular location conducive to major involvement in p

125 print designs this kinase to be regulated by subcellular location-dependent interactions with inhibit

126 bryonic kidney 293 (HEK293) cells, and their subcellular locations determined by confocal fluorescenc

127 sult in improved accuracy and sensitivity of subcellular location difference detection.

128 VA polymerization only occurs at the correct subcellular location during spore morphogenesis.

129 pathways are characterized by differences in subcellular location, electron transport molecules, and

130 Spatial restriction of mRNA to distinct subcellular locations enables local regulation and synth

131 s the destruction complex at the appropriate subcellular location, facilitating betacat destruction.

132 ce of mRNA translational repression and mRNA subcellular location for protein expression during B lym

133 G protein biology and redefine the ERES as a subcellular location for signal integration during morph

134 cellular transport of a 7TMR to its obligate subcellular location for signaling.

135 However, the subcellular location for SOCE in muscle fibers has not b

136 nnate immune signaling receptors that sample subcellular locations for foreign molecular structures,

137 vious systems for automated determination of subcellular location from microscope images has been don

138 he cAMP-dependent protein kinase to distinct subcellular locations, function as molecular scaffolds m

139 The alteration of phytochromes' subcellular location functions as a major regulatory mec

140 ins in Escherichia coli localize to specific subcellular locations, fundamental questions remain abou

141 ul high-throughput tool to determine protein subcellular location has become self-evident.

142 r preferential NMDAR inhibition depending on subcellular location has not been investigated systemati

143 infected neurons and the protein's specific subcellular location have not been determined.

144 s responsible for callose deposition in this subcellular location have not been identified.

145 some proteins may occur in several different subcellular locations, i.e. bear the feature of 'multipl

146 the ratio of TRAX to TB-RBP determines their subcellular locations, i.e. increased TRAX to TB-RBP rat

147 same score and ranking for several different subcellular locations, implying that they may simultaneo

148 rat liver microsomes, and rate of uptake and subcellular location in A549 and MCF-7 cells.

149 GH, we modulated its level of expression and subcellular location in Arabidopsis plants and tomato fr

150 mbrane domains, consistent with their unique subcellular location in the PG.

151 tilbenoid substrates, and we confirmed their subcellular location in the plastid by fluorescence micr

152 To ascertain the importance of eNOS subcellular location in this process, we used ECV-304 ce

153 and gamma-crystallins were found in distinct subcellular locations in adult lens epithelial cells.

154 of proteins are known to reside at specific subcellular locations in bacterial cells.

155 he determination of molecular hierarchies at subcellular locations in live cells.

156 ae were difficult to detect, we tested their subcellular locations in Physcomitrella patens transform

157 sory or scaffold protein, and positioning at subcellular locations in proximity to substrates.

158 predict proteins targeted to nine different subcellular locations in the eukaryotic animal species.

159 es have implicated restricted and surprising subcellular locations in which miRNA biogenesis or activ

160 acylation of protein plays a pivotal role in subcellular location including targeting to caveolae.

161 portantly, antigens were identified from all subcellular locations, including 18 integral membrane pr

162 reveal that 15-LOX2 is expressed at multiple subcellular locations, including cytoplasm, cytoskeleton

163 re coexpressed in the same cell had separate subcellular locations, indicating that Che2 proteins do

164 To address whether an antigen's subcellular location influences the nature and magnitude

165 Subcellular location is an important attribute of protei

166 ng the amount of protein distributed in each subcellular location is essential for quantitative under

167 K-Ras signaling specificity by altering its subcellular location is presented by Bivona et al.

168 onent of the mSin3 corepressor complex whose subcellular location is regulated by PML.

169 Trafficking between these subcellular locations is a regulated dynamic process.

170 uggest that trafficking of LANA to different subcellular locations is a regulated phenomenon, which a

171 ther enzyme specialization occurs in defined subcellular locations is unclear.

172 cified single cell among many, or a specific subcellular location, is still a largely unmet challenge

173 hus we have found a RTK fusion protein whose subcellular location leads to constitutive kinase activa

174 e describe the phylogeny, ultrastructure and subcellular location of 'Candidatus Adiutrix intracellul

175 from 11 studies using MetaMass, mapping the subcellular location of 5,970 proteins.

176 molecular function, biological process, and subcellular location of a gene product.

177 Knowledge of the subcellular location of a protein is crucial for underst

178 r role in drug resistance, we determined the subcellular location of ABCB6.

179 c42 and other guanosine triphosphatases, the subcellular location of activation is a critical determi

180 o accurately recapitulate the efficiency and subcellular location of arenavirus GPC processing.

181 The subcellular location of B. pseudomallei within infected

182 eal that not only the amplitude but also the subcellular location of conventional PKC signaling can b

183 Future studies are required to determine the subcellular location of each ACSL and ACSVL isoform and

184 ctions of these gene families, we report the subcellular location of each protein.

185 The subcellular location of enhanced green fluorescent prote

186 on of T cell proliferation by regulating the subcellular location of FoxO1 and FoxO3a, two Class O Fo

187 ectron microscopy were used to determine the subcellular location of FRalpha and PCFT in primary Mull

188 ar basis for this difference we compared the subcellular location of GFP fusions to the 126-kDa prote

189 Excess light regulates both the subcellular location of HSFA1D and its biochemical prope

190 We also visualized the subcellular location of ICEBs1.

191 The finding that the subcellular location of initiation sites and protein mic

192 racellular fluorescence NO probes to map the subcellular location of iNOS and NO under various condit

193 ral themes, with the abundance, activity and subcellular location of key structural and regulatory pr

194 ons provide a strong correlation between the subcellular location of mHTT, disruption of the nucleus,

195 ntly available methods for the prediction of subcellular location of mitochondrial proteins rely larg

196 experiments were performed to determine the subcellular location of MKK6, P-p38, and MAPKAPK2 (MK2).

197 Subcellular location of NA-TLRs is a key determinant in

198 alized to the cytoplasm, indicating that the subcellular location of NAD production is not crucial fo

199 reement regarding the potential function and subcellular location of Niemann-Pick C1-like 1 protein h

200 ediated gene transcription, depending on the subcellular location of NMDA receptors, as well as how s

201 y associated replisome is established by the subcellular location of oriC at the time of initiation o

202 play any detectable role in the activity or subcellular location of PKCdelta in cells; in vivo imagi

203 The specific subcellular location of posaconazole and the mechanism b

204 ' are necessary and sufficient to define the subcellular location of processing and to determine to w

205 veloped an automated pipeline to compare the subcellular location of proteins between two sets of imm

206 en used to reversibly manipulate the precise subcellular location of proteins in multicellular organi

207 of proteotoxicity is linked to change in the subcellular location of proteins that cause misfolding d

208 ived from these experiments is mostly of the subcellular location of proteins, and of the participati

209 We investigated the activation and subcellular location of Rac1 in FAK null and FAK reexpre

210 xpression of RD3 in different cell types and subcellular location of retina.

211 To evaluate the influence of Y RNA on the subcellular location of Ro60 during apoptosis and activa

212 ramatically expanded in the past decade, the subcellular location of small RNA-mediated RNA silencing

213 n fluorescent protein [GFP] fusion, that the subcellular location of Spo0J was a consequence of the c

214 proteolytic activity, without affecting the subcellular location of the enzyme.

215 Experimental characterization of the subcellular location of the protein confirmed that SA042

216 This dichotomy is partially explained by the subcellular location of the receptor.

217 equence similarity, we analyzed the possible subcellular location of their proteins as well as their

218 ortant activity of plant miRNAs, reveals the subcellular location of this activity, and uncovers a pr

219 together with substantial differences in the subcellular location of this protein between the frog an

220 of these three sites dramatically alters the subcellular location of Tmod-1 when introduced into mamm

221 d transporters was quantified by rt-PCR, and subcellular location of transporters was determined by i

222 We simultaneously examined the timing and subcellular location of two signaling molecules, MAPK (E

223 itoylation using resin-assisted capture, the subcellular location of yellow fluorescent protein-NCX1

224 P bodies in BMV replication, we examined the subcellular locations of BMV RNAs in yeast cells.

225 ort the protein interactions of Gis2 and the subcellular locations of both Gis2 and CNBP.

226 Furthermore, the activities and subcellular locations of both TcPOT1.1 and TcPOT1.2 in i

227 ned on normal tissue proteins to predict the subcellular locations of cancerous ones is arbitrary bec

228 In addition to documenting the subcellular locations of coding and noncoding transcript

229 We have visualized the subcellular locations of complexes formed by Myc/Max/Mad

230 Thus, the subcellular locations of D2 and CB1 receptors with respe

231 t study sought to determine the cellular and subcellular locations of ERbeta-ir.

232 hat provides a comprehensive analysis of the subcellular locations of Escherichia coli K-12 proteins.

233 port as well as the identity, functions, and subcellular locations of key exported proteins.

234 Despite their important roles, the subcellular locations of many novel thioredoxins has rem

235 staining pattern, which colocalizes with the subcellular locations of mitochondria and the Golgi appa

236 plasm and the nucleus, consistent with known subcellular locations of PIKKs.

237 (BiFC) analysis enables visualization of the subcellular locations of protein interactions in living

238 automatic recognition and comparison of the subcellular locations of proteins in microscope images.

239 Examining the subcellular locations of sequestered compounds in neuron

240 s poorly understood, as are the dynamics and subcellular locations of specific polyubiquitin signals.

241 sing immunohistochemistry to investigate the subcellular locations of TB-RBP and TRAX during spermato

242 We propose that the subcellular locations of TB-RBP and TRAX in male germ ce

243 Electron microscopy was used to assess the subcellular locations of TDP-O-decorated structures.

244 Although both the tissue-specific and subcellular locations of the encoded proteins require fu

245 The nonoverlapping subcellular locations of the three proteins and flavonoi

246 verexpressed in vegetative bacteria, and the subcellular locations of these GFP fusion sites were ana

247 immunogold labeling to determine whether the subcellular locations of these subunits were also altere

248 sites of viral proteolysis, thereby defining subcellular locations of virus priming with greater prec

249 ed after mitotic arrest, we investigated the subcellular location, oligomeric structure, and protein

250 current, suggesting that KS-WNK1 affects the subcellular location or activity but not the expression

251 may distinguish pumps with either different subcellular locations or biochemical functions.

252 rties on whole cells, ideally indicating the subcellular locations or cytoskeletal associations that

253 acteristic of particular cellular processes, subcellular locations or organs.

254 es in the myriad diseases linked to specific subcellular locations, particularly the lysosome.

255 s to intelligently acquire movies of protein subcellular location patterns by learning their models a

256 ss at building automated systems to classify subcellular location patterns in mammalian cells, we sou

257 In this subcellular location, PI3K-C2alpha controlled the activa

258 The nine subcellular locations predicted by pTARGET include cytop

259 Hh:GFP moved to basal subcellular locations prior to release from posterior co

260 unction and role are strongly related to its subcellular location, protein location prediction is an

261 n synaptic transmission is dictated by their subcellular location rather than their subunit compositi

262 by which Gag is targeted to the appropriate subcellular location remains poorly understood.

263 was conducted to determine the cellular and subcellular location(s) of the opioid growth factor rece

264 The subcellular location, sensitivity to pH changes, and dec

265 obe x-ray absorption measurements at various subcellular locations showed a near-edge feature that is

266 he benchmark data sets that covered up to 22 subcellular location sites and in which none of the prot

267 t at, or move between, two or more different subcellular location sites.

268 ce identity to any other protein in the same subcellular-location subset.

269 on, thermotolerance, senescence, or enriched subcellular locations such as the thylakoid lumen or chl

270 ate with cell adhesion molecules at discrete subcellular locations, such as the nodes of Ranvier.

271 biomarkers, proteins that undergo changes in subcellular location that are indicative of disease.

272 rm an active complex at the correct time and subcellular location through a series of incompletely un

273 into the nucleus or localize to a particular subcellular location to regulate Wnt signaling.

274 ization of eNOS is required to deliver NO to subcellular locations to increase endothelial monolayer

275 ust be processed stepwise and at the correct subcellular locations to produce the mature rRNAs.

276 a protein that has been observed at multiple subcellular locations, users may prioritize the visual d

277 Here, we report a study of their subcellular location using the cDNA clone resources of T

278 thm was developed for predicting the protein subcellular location using the strategy of hybridizing t

279 e labeled particles are retained at specific subcellular locations via DNA hybridization to intracell

280 In order to observe the impact of number of subcellular locations we constructed two more datasets o

281 facilitate systematic elucidation of protein subcellular location, we analyzed experimentally verifie

282 h tissue type, age, stage of cell cycle, and subcellular location, we determined the reduction potent

283 FRET)-based biosensors localized to discrete subcellular locations, we showed that both NGF and EGF p

284 f the existing methods in predicting protein subcellular location were used to deal with the cases li

285 ascorbate and oxalate/L-threonate, and their subcellular location, were unknown.

286 fractions of protein fluorescence in various subcellular locations when the basic locations in which

287 c accumulation of signaling endosomes at the subcellular location where BDNF concentration is maximal

288 However, the subcellular location where CRY2 exerts its function or u

289 -secretase-mediated processing, although the subcellular location where gamma-secretase cleaves Notch

290 However, the subcellular location where Gbetagamma acts to provoke Go

291 Moreover, the subcellular location where PI(3,5)P(2) regulates TORC1 w

292 Although the SEN complex is conserved, the subcellular location where pre-tRNA splicing occurs is n

293 ich these proteins prevent secretion and the subcellular location where the block in secretion occurs

294 In particular, the subcellular location where this process takes place is u

295 alysis and do not provide information on the subcellular locations where this lipid is synthesized.

296 1 and PDE4 isoforms are targeted to specific subcellular locations which may contribute to the compar

297 ns to probe biochemical pathways at specific subcellular locations with exquisite temporal control.

298 rabidopsis proteins have a manually assigned subcellular location, with a strong emphasis on plastid

299 3 also differs from VGLUT1 and VGLUT2 in its subcellular location, with somatodendritic as well as ax

300 data suggest that Nkd acts at more than one subcellular location within signal-receiving cells to at