ライフサイエンスコーパス: subclinical

1 identical but not clinically correlated, or subclinical.

2 f brain magnetic resonance imaging (MRI) and subclinical abnormalities among asymptomatic individuals

3 r heart failure, obesity was associated with subclinical abnormalities in cardiac structure in both m

4 ata highlight the association of obesity and subclinical abnormalities of cardiac structure and funct

5 rformed at 30 days posttransplant to capture subclinical abnormalities.

6 s with pulmonary abnormalities suggestive of subclinical, active disease who were substantially more

7 Subclinical acute rejection (sc-AR) is a main cause for

8 Subclinical acute rejection was observed in 22 (29.3%) p

9 ther trials regarding the value of detecting subclinical AF and of prophylactic therapies are warrant

10 identify people at high risk for developing subclinical AF and will evaluate the efficacy, safety, a

11 Observations: Subclinical AF is asymptomatic, short in duration, and u

12 The treatment of subclinical AF may be a useful stroke prevention strateg

13 F genetic risk may improve identification of subclinical AF or help distinguish between stroke mechan

14 veness of screening for and the treatment of subclinical AF will require additional study.

15 dentifying African American individuals with subclinical and clinical atherosclerotic cardiovascular

16 Subclinical and clinical cardiac diseases have been prev

17 ve not been studied, to date, in relation to subclinical and clinical cardiac diseases.

18 contribute to the disproportionate burden of subclinical and clinical cardiovascular disease among ad

19 0:Cr improved the diagnostic performance for subclinical and clinical inflammation/injury by integrat

20 :Cr for distinguishing normal histology from subclinical and clinical inflammation/injury, but not su

21 , 1.11; 95% CI, 0.67-1.83, respectively, for subclinical and clinical new-onset atrial fibrillation).

22 rs, suggesting important differences between subclinical and clinical psychosis.

23 Subclinical and electrical staged ARVC subjects already

24 to spores of pathogenic fungi can result in subclinical and unrecognised syndromes, allergic manifes

25 ations in aversive pruning levels related to subclinical anxiety levels and insular cortex activation

26 r risk factors, increased odds of presenting subclinical atherosclerosis (odds ratio: 1.31; 95% confi

27 without diabetes in the Progression of Early Subclinical Atherosclerosis (PESA) Study.

28 Subclinical atherosclerosis (plaque or coronary artery c

29 t high genetic risk have a greater burden of subclinical atherosclerosis and derive greater relative

30 ts in protein-coding regions associated with subclinical atherosclerosis and the risk of subsequent c

31 Whether the incidence and severity of subclinical atherosclerosis are associated with the abun

32 patients with psoriasis harbor high rates of subclinical atherosclerosis beyond adjustment for body m

33 ional exploration of the association between subclinical atherosclerosis burden and both average LTL

34 Early subclinical atherosclerosis has been mainly researched i

35 isk assessed in young adulthood years before subclinical atherosclerosis imaging provide strong predi

36 Detection of subclinical atherosclerosis improves risk prediction bey

37 cteristics are related to the progression of subclinical atherosclerosis in 5950 adult participants o

38 The burden of subclinical atherosclerosis in asymptomatic individuals

39 This study sought to identify predictors of subclinical atherosclerosis in CVRF-free individuals.

40 Subclinical atherosclerosis in patients with psoriasis h

41 pecific guidelines that include detection of subclinical atherosclerosis may help to identify HIV-inf

42 CpG sites were consistently associated with subclinical atherosclerosis measures (coronary calcium s

43 e first significant association for multiple subclinical atherosclerosis traits across multiple ethni

44 Subclinical atherosclerosis was assessed in 2029 partici

45 Subclinical atherosclerosis was evaluated by coronary ar

46 Subclinical atherosclerosis was found in 72% of particip

47 Subclinical atherosclerosis was highly prevalent in this

48 Subclinical atherosclerosis was measured in right and le

49 th scores predict the presence and extent of subclinical atherosclerosis with similar accuracy, highl

50 e enrolled in the PESA (Progression of Early Subclinical Atherosclerosis) cohort.

51 icipants from the PESA (Progression of Early Subclinical Atherosclerosis) study (n = 4,184) without c

52 ded 3,860 (92.2%) PESA (Progression of Early Subclinical Atherosclerosis) study participants (age 45.

53 formed within the PESA (Progression of Early Subclinical Atherosclerosis) study, a prospective cohort

54 From a population-based study on subclinical atherosclerosis, 40 participants with IPH at

55 ed tomographic angiography for assessment of subclinical atherosclerosis, and systemic immune and met

56 s was evaluated by measuring (1) presence of subclinical atherosclerosis, assessed by coronary artery

57 osclerosis throughout its spectrum; that is, subclinical atherosclerosis, incident atherosclerotic ca

58 the presence, distribution, and extension of subclinical atherosclerosis.

59 eligibility using noninvasive assessment of subclinical atherosclerosis.

60 imaging provide strong prediction of future subclinical atherosclerosis.

61 not significant independent determinants of subclinical atherosclerosis.

62 s between telomere length and progression of subclinical atherosclerosis.

63 ing variants in APOB and APOE associate with subclinical atherosclerosis.

64 FBS in predicting the presence and extent of subclinical atherosclerosis.

65 Subclinical atrial fibrillation (AF) is associated with

66 ws a substantial prevalence of asymptomatic, subclinical atrial fibrillation (SCAF) in patients with

67 e of undetermined source may often stem from subclinical atrial fibrillation, which can be diagnosed

68 ry, acute respiratory failure, and new-onset subclinical atrial fibrillation, which occurred in 8% of

69 r autonomic neuropathy, whereas 2 others had subclinical autonomic dysfunction.

70 e, paratyphoid was notable for high rates of subclinical bacteremia (at this dose, 11/20 [55%]).

71 (18)F-FLT imaging objectively identified subclinical bone-marrow recovery within 5 days of HSC in

72 F-FLT allowed quantification and tracking of subclinical bone-marrow repopulation in human beings and

73 nicians as to both the clinical relevance of subclinical BPV thrombosis and the value of empirical or

74 is a marker of heart disease, and markers of subclinical brain damage on magnetic resonance (MR) imag

75 en NT-proBNP level and MR imaging markers of subclinical brain damage, including volumetric, focal, a

76 ic and microstructural MR imaging markers of subclinical brain damage.

77 g non-coding RNAs (lncRNAs) as biomarkers of subclinical cardiac abnormalities in type 2 diabetes.

78 amine the association of blood biomarkers of subclinical cardiac disease and clinically manifest card

79 This study found that biomarkers of subclinical cardiac disease and clinically manifest card

80 y represent a biochemical signature of early subclinical cardiac disease, providing an opportunity fo

81 tional impairment associated with persistent subclinical cardiac dysfunction.

82 T cell proliferative expansion, transforming subclinical cardiac injury to overt heart failure.

83 Lone atrial fibrillation (AF) may reflect a subclinical cardiomyopathy that persists after sinus rhy

84 t that PM2.5 exposure may be associated with subclinical cardiopulmonary differences in this general

85 ing in FD on cardiovascular risk factors and subclinical cardiovascular disease (CVD) with the hypoth

86 endent sample cohort of middle-aged men with subclinical cardiovascular disease in the Aragon Workers

87 ation between socioeconomic status (SES) and subclinical cardiovascular disease is not well understoo

88 effects of estimated sodium intake (ESI) on subclinical cardiovascular disease.

89 study sought to evaluate the association of subclinical carotid and femoral plaques with risk factor

90 lated with dsPMCAb-derived material were not subclinical carriers of scrapie, as no PrP(Sc) was detec

91 cores, and retained accuracy when applied to subclinical cases (creatinine, <25% increase from baseli

92 may not be generalizable to less severe and subclinical cases of mitral regurgitation.

93 Silent or subclinical celiac disease may result in potentially avo

94 obvious symptoms and the natural history of subclinical celiac disease.

95 s potential as a tool to assess for early or subclinical changes in LV function, and strain is now be

96 ne whether the SIC could be used to identify subclinical changes in patients at risk for HCM and to e

97 Subclinical changes preceded the date of conversion and

98 Subclinical CMV replication in blood cells during early

99 Higher levels of subclinical CMV replication were associated with lower p

100 tions exhibit neuropathy without clinical or subclinical CNS abnormalities.

101 quired for relapse-free survival, indicating subclinical CNS manifestation in most patients.

102 Subclinical cognitive impairment is prevalent in heart f

103 Current noninvasive tests that assess for subclinical coronary and myocardial disease have low sen

104 uld be partially attributable to an elevated subclinical coronary artery disease burden composed of n

105 her cardiovascular risk factors and advanced subclinical coronary atherosclerosis in risk stratificat

106 y/American Heart Association guidelines, and subclinical coronary atherosclerosis was assessed by com

107 at high genetic risk had a greater burden of subclinical coronary atherosclerosis.

108 GlycA associated with psoriasis severity and subclinical CVD beyond traditional CV risk and high-sens

109 (diabetes, hypertension, hyperlipidemia) or subclinical CVD measures (coronary artery calcification,

110 ndings support the potential use of GlycA in subclinical CVD risk assessment in psoriasis and potenti

111 Progression of subclinical CVD was defined by 10-year change in left ve

112 rences in risk factors for CVD or markers of subclinical CVD.

113 In this study, we investigated the effect of subclinical cytomegalovirus (CMV) and Epstein-Barr virus

114 iovascular screening identified considerable subclinical disease among adult survivors of childhood c

115 d testing is suitable for early detection of subclinical disease and how antifungal prophylaxis impac

116 hese methods may lead to greater insights on subclinical disease markers without apriori assumptions

117 mellitus, and smoking; blood biomarkers; and subclinical disease measures, including ankle-brachial i

118 ght forth new light by allowing detection of subclinical disease not readily visible with the naked e

119 .9-year-old boys with DMD and able to detect subclinical disease progression in DMD, even within shor

120 ubjects with prediabetes show early signs of subclinical disease that include vascular, cardiac, and

121 MESA was designed to study progression of subclinical disease to cardiovascular events where parti

122 We assessed subclinical disease using coronary artery calcium (CAC).

123 PSC appears to progress in patients with subclinical disease, but long-term outcomes are not know

124 affordable score for evaluating the risk of subclinical disease.

125 asymptomatic child contacts at high risk for subclinical disease.

126 tem infection dynamics demonstrated that the subclinical divergence between FMDV carriers and animals

127 ed the prognostic value of LV remodeling and subclinical dysfunction.

128 eported on a cohort of HIV-negative men with subclinical endotoxemia linked to alterations in CD4/CD8

129 ging primary endpoint was detection of early subclinical engraftment after HSCT with (18)F-FLT PET or

130 Extended monitoring detects subclinical epileptiform activity in a substantial propo

131 However, the incidence of subclinical epileptiform activity in AD and its conseque

132 e hypothesized higher than expected rates of subclinical epileptiform activity in AD with deleterious

133 Some evidence indicates that subclinical epileptiform activity in patients with Alzhe

134 However, patients with subclinical epileptiform activity showed faster declines

135 Subclinical epileptiform activity was assessed, blinded

136 Subclinical epileptiform activity was detected in 42.4%

137 sed risk of developing NMSCs with aggressive subclinical extensions (NMSC-ASE), which may extend aggr

138 -7 levels may be a quantitative biomarker of subclinical extracellular matrix remodeling in the lungs

139 Elevated NT-proBNP is related to subclinical fibrosis in a community-based setting.

140 When differentiating subclinical from normal corneas, BAD-D was similar to th

141 toff values might be needed to differentiate subclinical from normal corneas.

142 as 61% higher in overt HCM and 47% higher in subclinical HCM (P<0.001 for both).

143 medicalisation (definition and treatment of subclinical heart problems without high-level evidence f

144 ecreased postdonation eGFR, whereas no other subclinical histological abnormalities provided addition

145 tween myeloablative infusion before HSCT and subclinical HSC recovery (p=0.00031).

146 The risk of AF is increased in subclinical hyperthyroidism, but it is uncertain whether

147 sociation of TSH levels in the euthyroid and subclinical hypothyroid range with incident AF was exami

148 rome were at a 21% excess risk of developing subclinical hypothyroidism (adjusted HR 1.21; 95% CI 1.0

149 least 65 years of age and who had persisting subclinical hypothyroidism (thyrotropin level, 4.60 to 1

150 person-years of follow-up), 1958 (6.5%) had subclinical hypothyroidism and 2574 individuals (8.6%) d

151 ses have demonstrated an association between subclinical hypothyroidism and metabolic syndrome and se

152 thyroid function within the normal range or subclinical hypothyroidism are also associated with AF.

153 lating hormone (TSH) 0.45 to 4.49 mIU/L, and subclinical hypothyroidism as TSH 4.5 to 19.9 mIU/L with

154 It found adequate evidence that treating subclinical hypothyroidism does not provide clinically m

155 The use of levothyroxine to treat subclinical hypothyroidism is controversial.

156 Subclinical hypothyroidism is known to be associated wit

157 Treatment for subclinical hypothyroidism or hypothyroxinemia beginning

158 atment of women who are identified as having subclinical hypothyroidism or hypothyroxinemia during pr

159 scuss their perspectives on whether treating subclinical hypothyroidism reduces morbidity and mortali

160 In the subclinical hypothyroidism trial, the median IQ score of

161 A total of 677 women with subclinical hypothyroidism underwent randomization at a

162 mponents were analyzed, an increased risk of subclinical hypothyroidism was associated with high bloo

163 Clinical and subclinical hypothyroidism were associated with worse Gl

164 llow-up of 4.2 years, the incident rates for subclinical hypothyroidism were substantially higher in

165 n pregnancy before 20 weeks of gestation for subclinical hypothyroidism, defined as a thyrotropin lev

166 yndrome are at a greater risk for developing subclinical hypothyroidism, while its mechanisms and tem

167 t AF in euthyroid participants or those with subclinical hypothyroidism.

168 d no apparent benefits in older persons with subclinical hypothyroidism.

169 to VGDF were associated with measurements of subclinical ILD in community-dwelling adults.

170 mputed tomography (CT)-based measurements of subclinical ILD, respectively.

171 Human infections range from subclinical illness to severe disease resulting in death

172 Chronic low-grade inflammation reflects a subclinical immune response implicated in the pathogenes

173 on during acute infection of a naive host is subclinical in most individuals.

174 estigating the clinical impact of this often subclinical infection on the severity of respiratory dis

175 The clinical manifestations range from subclinical infection to severe manifestations of focal

176 Subclinical infection was present in 40% of patients wit

177 fear that some animals may have undiagnosed subclinical infection, despite uncertainty over the biol

178 Sixty percent of neutrophilic patients had a subclinical infection.

179 roorganism in BAL culture, which suggested a subclinical infection.

180 poor birth outcomes to measure the burden of subclinical infections and elucidate pathological mechan

181 vers tested positive (2/81), suggesting that subclinical infections are uncommon.

182 spiratory pathogens that often cause mild or subclinical infections.

183 that limit detection especially in early and subclinical infections.

184 al and clinical inflammation/injury, but not subclinical inflammation alone.

185 chondrial DNA (mtDNA) deletions and chronic, subclinical inflammation are concomitant during skin agi

186 The subclinical inflammation assisted by obesity-induced gut

187 Corneas with subclinical inflammation developed significantly greater

188 Early subclinical inflammation in surveillance biopsies with o

189 This suggests that subclinical inflammation is present and that natural ant

190 has already occurred, fail to detect chronic subclinical inflammation that can negatively affect graf

191 t persisted without loss of corneal clarity (subclinical inflammation).

192 ht be involved in the development of chronic subclinical inflammation.

193 creased titin phosphorylation and suppressed subclinical inflammation.

194 Subclinical inflammatory demyelination and neurodegenera

195 f a broad range of occupational exposures on subclinical interstitial lung disease (ILD) has not been

196 dults, which may facilitate investigation of subclinical interstitial lung disease.

197 egy for uveitis through the stabilization of subclinical intestinal alterations that occur in inflamm

198 This study included 42 normal, 37 subclinical keratoconic, and 51 keratoconic eyes seen in

199 For subclinical keratoconus, the highest sensitivity (100%)

200 ng and ongoing haemolytic anaemia, even when subclinical, lead to parenchymal injury and chronic orga

201 of novel oral anticoagulants (NOACs) on the subclinical leaflet thrombosis and subsequent valve haem

202 We defined subclinical leaflet thrombosis as the presence of reduce

203 A greater proportion of patients with subclinical leaflet thrombosis had aortic valve gradient

204 f this study was to report the prevalence of subclinical leaflet thrombosis in surgical and transcath

205 neration valves, prevention and treatment of subclinical leaflet thrombosis might offer a potential o

206 INTERPRETATION: Subclinical leaflet thrombosis occurred frequently in bi

207 Subclinical leaflet thrombosis of bioprosthetic aortic v

208 Subclinical leaflet thrombosis resolved in 36 (100%) of

209 Subclinical leaflet thrombosis was associated with incre

210 rson-years) reduced leaflet motion (p=0.10), subclinical leaflet thrombosis was associated with incre

211 Subclinical leaflet thrombosis was less frequent among p

212 106 (12%) of 890 patients had subclinical leaflet thrombosis, including five (4%) of 1

213 was effective in prevention or treatment of subclinical leaflet thrombosis.

214 eipt of large monetary losses, and also with subclinical levels of anxiety.

215 evels from each individual, we now show that subclinical levels of plasma LPS in vivo significantly a

216 Clinical and subclinical lipodystrophy was not noted in those younger

217 bal longitudinal strain (GLS) is a marker of subclinical LV dysfunction.

218 Quantitative OCTA parameters reveal subclinical macular ischemia at both the superficial and

219 Initially he showed subclinical magnetic resonance imaging (MRI) changes (ra

220 tients with MS are more likely to have early subclinical manifestations of MS.

221 ral blood lymphocytes in cows with S. aureus subclinical mastitis (SA group) and healthy controls (CK

222 Subclinical mastitis is a widely spread disease of lacta

223 es and pathways relevant to bovine S. aureus subclinical mastitis.

224 otypes above and beyond body mass index with subclinical measures of LV mechanical function.

225 Identifying these individuals with subclinical metabolic acidosis is challenging, but recen

226 Subclinical MG was subsequently induced with a low dose

227 blishRnaseh2b(A174T/A174T)knock-in mice as a subclinical model of disease, identifying significant in

228 provide novel evidence for the existence of subclinical motor dysfunction at a pre-clinical stage of

229 tically showed fatty atrophy in clinical and subclinical mutation carriers.

230 pulse pressure, low DBP was associated with subclinical myocardial damage and CHD events.

231 However, diabetic female rats develop early subclinical myocardial deformation, cardiac hypertrophy

232 and function in addition to higher rates of subclinical myocardial edema and fibrosis and frequent p

233 Subclinical myocardial inflammation as detected by CMR m

234 In DM2, subclinical myocardial injury was already detectable in

235 moking is mediated via mechanisms other than subclinical myocardial injury.

236 8; p = 0.0001), but were not associated with subclinical myonecrosis (OR: 1.14; p = 0.3147).

237 titial fibrosis and tubular atrophy (n = 6), subclinical (n = 6) and clinical rejection (n = 6), unde

238 Subclinical ONHD may be more prevalent than previously b

239 Significant associations of subclinical ONHD with smaller ONH and shorter axial leng

240 x inherited neurological diseases and may be subclinical or a major component of the phenotype.

241 Although MERS-CoV generally causes subclinical or mild disease, infection can result in ser

242 ly been linked to adult-onset diabetes, with subclinical or no exocrine insufficiency, suggesting an

243 he only factor independently associated with subclinical or unrecognized cardiac dysfunction (odds ra

244 spanics/Latinos, most cardiac dysfunction is subclinical or unrecognized, with a high prevalence of d

245 New-onset atrial fibrillation was subclinical or went undocumented in 626, or 8% of all IC

246 lammation (P = 0.04), borderline (P = 0.08), subclinical (P = 0.01) and clinical rejection (P = 0.000

247 There were two minor AEs-subclinical pancreatitis and a mucosal ulcer that had he

248 score (and derivations of this) to identify subclinical parkinsonism, and association of risk estima

249 oportion of individuals classified as having subclinical parkinsonism.

250 in 69% of patients with CSPH versus 35% with subclinical PHT (P < 0.001) and decreased >/=20% in 40%

251 Therefore, documenting subclinical Pneumocystis infection induces lung disease

252 ips to MRS glutamate and amphetamine-induced subclinical positive symptoms were detected.

253 gs suggest a clinically relevant spectrum of subclinical primary aldosteronism (renin-independent ald

254 Subclinical primary Pneumocystis infection is the most c

255 The Egyptian rousette develops subclinical productive infection with MARV but is refrac

256 Sixty-five percent of patients had subclinical PSC associated with progressive IBD, with no

257 groups and correlations with MRS glutamate, subclinical psychopathological and neurocognitive parame

258 ds to other extrastriatal areas and predicts subclinical psychopathology.

259 Having arthritis increased the odds of subclinical psychosis (OR = 1.85; 95%CI = 1.72-1.99) and

260 r adolescents exhibited an increase in their subclinical psychotic symptoms as a function of their re

261 rijuana use exhibit a systematic increase in subclinical psychotic symptoms that persists during peri

262 esent in herpetic ulcerations, their role in subclinical reactivation and persistence is less well kn

263 r cell (NS/PC) transplantation exerts only a subclinical recovery; this in contrast to its remarkable

264 We believe that subclinical rejection (SCR) may be 1 of the factors that

265 cal rejection [sc-TCMR], 5 antibody-mediated subclinical rejection [sc-ABMR]), whereas 53 (70.7%) sho

266 d in 22 (29.3%) patients (17 T cell-mediated subclinical rejection [sc-TCMR], 5 antibody-mediated sub

267 onal outcome in studies in which the rate of subclinical rejection in the first 3 months was greater

268 nclude but are not limited to: prevention of subclinical rejection in the first year, better 5- and 1

269 Treatment of subclinical rejections has only proven beneficial to his

270 To investigate whether a spectrum of subclinical renin-independent aldosteronism that increas

271 that memory TFH play a role in the latent or subclinical reservoir of HIV during antiretroviral thera

272 Overall, these findings suggest that subclinical seeding of the CNS is likely to be present i

273 logic monitoring data to identify such early subclinical signatures of incipient life-threatening ill

274 (CNS) abnormality in males, including stable subclinical signs and, less often, short-duration episod

275 and plasma cells with some horses displaying subclinical signs of hepatitis.

276 hors provide an overview of the clinical and subclinical spectrum of BPV thrombosis of surgical and T

277 ma (LMM) is challenging because of extensive subclinical spread and its occurrence on cosmetically se

278 f 2010 International Task Force criteria: 1) subclinical stage (n = 21); 2) electrical stage (n = 15)

279 uberculosis (MAP) infection during the early subclinical stage are still not clear.

280 ts that are associated with progression from subclinical stage to overt HF.

281 eased in unmedicated persons presenting with subclinical symptoms indicating that they are at ultra h

282 ated disorders, as well as the expression of subclinical symptoms.

283 te of reactivation or a decrease in imported subclinical TB - could accurately describe the trajector

284 pite its ubiquity, infection by EBV is often subclinical; this invariably reflects the necessity of t

285 l computed tomographic imaging for detecting subclinical thrombi upon both surgically implanted and T

286 AMR was associated with subclinical thrombotic microangiopathy in 2 patients.

287 A total of 23 patients had subclinical THV thrombosis, whereas 5 (18%) patients exp

288 Although often subclinical, THV thrombosis may have important clinical

289 Subclinical thyroid disease during pregnancy may be asso

290 essed the effect of treating screen-detected subclinical thyroid dysfunction on health outcomes.

291 Safety scales did not reveal subclinical toxicity with deutetrabenazine treatment.

292 y is recommended in HIV-positive adults, but subclinical tuberculosis can be difficult to diagnose.

293 icyte ablation also led to hypoxic focal and subclinical tubular injury, reflected by transient expre

294 atic triglyceride content is associated with subclinical vascular impairment and is not confounded by

295 pecific contribution of hepatic steatosis to subclinical vascular impairment.

296 in antigen-specific T cell responses during subclinical viral myocarditis.

297 r proportion of patients in r-ATG/EVR showed subclinical WHAE (13% vs 7% vs 4%, P = 0.025) compared w

298 % vs 22.0%, P = 0.03) and total clinical and subclinical WHAE (35% vs 42% vs 26%, P = 0.014) compared

299 owed a higher risk of developing clinical or subclinical WHAE (r-ATG/EVR vs BAS/MPS hazard ratio 1.30

300 th higher incidence of combined clinical and subclinical WHAE compared with MPS.