ライフサイエンスコーパス: subcortical

1 vity, cortical thickness), both cortical and subcortical.

2 To characterize neurophysiological subcortical abnormalities in myoclonus-dystonia and thei

3 DOCK8 is essential for the integrity of the subcortical actin cytoskeleton as well as for TCR-driven

4 tail of MT1-MMP and its ability to bind the subcortical actin cytoskeleton.

5 E may lead to abnormal connections involving subcortical activating structures including the ascendin

6 a power from each contact pair onto standard subcortical anatomy.

7 invert or exaggerate sex and SCA effects on subcortical anatomy.

8 l neural responses to audiovisual signals in subcortical and cortical areas [1-5].

9 mpanied by nociceptive activity generated in subcortical and cortical areas of the brain [1, 2].

10 top-down inhibitory modulation from maturing subcortical and cortical brain networks.

11 tions in [(11)C]carfentanil BPND in multiple subcortical and cortical brain regions and in striatal [

12 ultiple white matter tracts known to connect subcortical and cortical brain regions.

13 metries of neuroanatomical structures across subcortical and cortical brain regions.

14 concurrent and interdependent remodeling of subcortical and cortical circuits in response to sensory

15 blunted neural responses within distributed subcortical and cortical regions including the striatum,

16 h severe, prolonged deficits following lower subcortical and midbrain injury.

17 l problems at an early age show differential subcortical and white matter development.

18 ume fraction were found in several cortical, subcortical and white matter regions when patients were

19 learning has been related to many cortical, subcortical, and cerebellar structures.

20 cortex is a dense network composed of local, subcortical, and intercortical synaptic connections.

21 The midbrain is an important subcortical area involved in distinct functions such as

22 of glutamatergic boutons are present in many subcortical areas and often are associated with inhibito

23 Notably, stable controllers in subcortical areas are negatively related to cognitive pe

24 n regions, including neocortical, limbic and subcortical areas from Alzheimer's disease cases (n = 19

25 ltaneously record from up to 37 cortical and subcortical areas in awake behaving monkeys for up to 9

26 nally viewed as being innately programmed in subcortical areas of the brain, and are often treated as

27 antly increased in cortical but decreased in subcortical areas, and the coupling between them was dec

28 M2 in turn connect to different cortical and subcortical areas, as determined by anterograde tract tr

29 equires the interaction of many cortical and subcortical areas, for example the superior colliculus (

30 ale brain in 10 out of 11 sexually dimorphic subcortical areas, in contrast to the overall larger bra

31 ts in 33%-53% of cortical regions and 80% in subcortical areas.

32 ed beta synchronization between cortical and subcortical areas.

33 ayer 5B (L5B) connect the cortex to numerous subcortical areas.

34 o distinguishing inhibitory subtypes in many subcortical areas.

35 s (PTs) - send axonal projections to various subcortical areas.

36 d not seem to propagate to other cortical or subcortical areas.

37 rated region-selective roles of cortical and subcortical astrocytes in regulating cortical or subcort

38 Interestingly, cortical or subcortical astrocytes selectively promote neurite growt

39 Motor and subcortical auditory brain activity covaries with the au

40 coding, in which spontaneous activity in the subcortical auditory pathway constitutes a 'tinnitus pre

41 These results imply the 5-HTTLPR in subcortical auditory speech encoding and add an importan

42 ed whether such modulation occurs already in subcortical auditory structures.

43 lighted the encoding of speech sounds in the subcortical auditory system as being shaped by acoustic,

44 to a lesser extent, Ascl1, extended aberrant subcortical axon projections characteristic of early-bor

45 The HeCo mutant mouse exhibits subcortical band heterotopia (SBH), likely to be initiat

46 rrently largest worldwide effort to identify subcortical brain alterations showed robust smaller hipp

47 ctional interactions between key frontal and subcortical brain areas for response inhibition, by comp

48 hedonic controls of appetite by cortical and subcortical brain areas processing external sensory info

49 bly translating) mRNAs in major cortical and subcortical brain regions (cortex, hippocampus, caudate-

50 le anatomical segregation, with cortical and subcortical brain regions contributing to different func

51 A large network of cortical and subcortical brain regions control cardiovascular functio

52 Several cortical and subcortical brain regions respond selectively to threat.

53 ons in prefrontal cortical interactions with subcortical brain regions, such as the amygdala, are eme

54 ity in bilateral hemispheres of cortical and subcortical brain regions.

55 ns of FMRP distribution in both cortical and subcortical brain regions.

56 act of polygenic risk of MDD, SCZ, and BP on subcortical brain volumes and white matter (WM) microstr

57 These findings suggest that subcortical brain volumes and WM microstructure may not

58 splayed significantly extensive cortical and subcortical brain volumes atrophy compared with controls

59 We identified subcortical brain volumes that differentiated patients f

60 m 15 research samples worldwide, to identify subcortical brain volumes that robustly discriminate MDD

61 s are shared with neuropsychiatric traits or subcortical brain volumes.

62 g +/- 0.078 and 0.051 mug/g +/- 0.009 in the subcortical brain, and 0.781 mug/g +/- 0.079 and 0.061 m

63 owing activity and connectivity of a cortico-subcortical "braking" network that positively scaled wit

64 apsed skull; (2) thin cerebral cortices with subcortical calcifications; (3) macular scarring and foc

65 bserved in different cell populations in the subcortical cerebellar structures.

66 sease-specific and correspond to cortical or subcortical changes in neurodegenerative conditions.

67 Subcortical (chi(2) (1)=4.65, P=0.031) and lobular (chi(

68 dence suggests the potential significance of subcortical cholinergic innervation in the evolution of

69 erns of connectivity between frontoparietal, subcortical, cingulo-opercular, and default-mode network

70 iable reduced and exaggerated prefrontal and subcortical circuit functions were accentuated in patien

71 of cortical visual processing extends to the subcortical circuit that mediates a very basic reflex, t

72 c responses cannot be entirely attributed to subcortical circuitry as V1 lesions alter the fraction o

73 We examined cortical-subcortical circuitry engaging anterior and dorsolateral

74 Dynamic causal models examined cortical-subcortical circuitry interactions at context change inf

75 However, while the subcortical circuitry responsible for processing and exp

76 Although subcortical circuits are not directly responsible for co

77 ircuits are necessary for learning, but that subcortical circuits are sufficient to drive learned beh

78 xamine the integrity of key nodes in frontal-subcortical circuits in four subject groups: patients di

79 f motivationally relevant cues are biased by subcortical circuits that drive specific motivational st

80 plasticity not seen in other sensory system subcortical circuits.

81 function relying on widespread cortical and subcortical circuits.

82 d potentials elicited by cortical (MEPs) and subcortical (CMEPs) stimulation of corticospinal axons a

83 ictive classifier, encompassing cortical and subcortical components, has a significant discriminative

84 Possibly the best-studied L5B cortico-subcortical connection is that between L5B neurons in th

85 s revealed a clear temporal advantage of the subcortical connection over the cortical connection in i

86 can enhance downstream modulation of frontal-subcortical connections for response inhibition; and (ii

87 Most subcortical connections were ipsilateral, but some were

88 via changes in the prefrontal cortex and its subcortical connections.

89 TION: The cerebellum has strong cortical and subcortical connectivity, but is rarely taken into accou

90 We estimated low cortico-subcortical convergence and divergence, demonstrating th

91 one pathophysiological mechanism influencing subcortical-cortical propagation of sleep spindles and t

92 suggest that both treatments improved cortex-subcortical coupling in remissive CD patients, but elect

93 The hand blink reflex is a subcortical defensive response, known to dramatically in

94 ening stimulus is delivered inside the DPPS, subcortical defensive responses like the hand-blink refl

95 (IC) of the mouse revealed that most of the subcortical descending projections originated in the bra

96 ment in symptomatic CAD, which suggests that subcortical disconnection within large-scale cognitive n

97 We also observed increased subcortical dopamine levels in fatigued mice: a marker o

98 thalamic relays: first order relays receive subcortical driver input (for example, retinal input to

99 These opposing cortical-subcortical effects relate in part to genetic risk for s

100 We recorded subcortical electrophysiological responses to an English

101 We computed differences in activation in the subcortical face processing system (superior colliculus,

102 selective activity in adjacent cortical and subcortical face-selective areas (i.e., FFA and amygdala

103 erved a monocular advantage, which indicates subcortical facilitation, for ancestral threats (snakes,

104 ion of multiple cortico-cortical and cortico-subcortical FC networks.

105 tion fiber pathways, commissural fibers, and subcortical fiber bundle.

106 frontal lobes, which when combined with the subcortical findings, suggests that iron accumulation wi

107 tive impairment (n = 42), those with frontal subcortical (FSC) dysfunction (n = 29), those with Papez

108 tive impairment (n = 42), those with frontal subcortical (FSC) dysfunction (n = 29), those with Papez

109 tly overlapping cortico-cortical and cortico-subcortical functional connectivity (FC) networks.

110 cm3), WMV (31.7; 95% CI, 19.7-43.7 cm3), and subcortical GMV (1.8; 95% CI, 0.8-2.8 cm3).

111 cally definite MS, fractions of cortical and subcortical gray matter and cerebral white matter, brain

112 with younger age at onset and the atrophy of subcortical gray matter fraction in women with relapsing

113 baseline predicted smaller increases in both subcortical gray matter volume and global fractional ani

114 se of MRI cortical thickness measurement and subcortical gray matter volumetry could provide an early

115 In this study, we tested for differences in subcortical grey matter volume (n = 1157) and white matt

116 For each subject, cortical and subcortical grey matter volumes were generated using a p

117 pine deficits in the DLPFC may contribute to subcortical hyperdopaminergia in schizophrenia.

118 ssociated with an increased risk of incident subcortical infarcts (adjusted risk ratio, 2.54; 95% CI,

119 erebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) i

120 infarcts, and large cortical and non-lacunar subcortical infarcts).

121 Incident subcortical infarcts, cerebral microbleeds, and progress

122 The L5B subcortical innervation is target specific in terms of b

123 rtex, and found that excitatory cortical and subcortical inputs are refined by the fourth week of dev

124 ated areas, the cortico-cortical and cortico-subcortical interactions of which evolve rapidly and rec

125 ct distinct, measurable patterns of cortical-subcortical interactions.

126 ay result from distinct patterns of cortical-subcortical interactions.

127 , P = .060; acute lesions, P = .088; chronic subcortical ischemic lesions, P = .085).

128 s of acute (P = .028) and chronic (P = .009) subcortical ischemic lesions.

129 lesions would impair hand function more than subcortical lesions.

130 actors play a role in speech encoding at the subcortical level remains unresolved.

131 vivo studies are sparse, particularly at the subcortical level.

132 fundamental sensory and motor processing at subcortical levels to FXS pathology.

133 groups expressing high levels of FMRP at the subcortical levels, in particular sensory and motor neur

134 rgic alterations, reaching both cortical and subcortical levels, including the Ch5 pathway and the st

135 thin prefrontal cortex and a large number of subcortical limbic areas (e.g., amygdala, lateral hypoth

136 t of view of their bearing on and fit with a subcortical locus of sensory experience.

137 contagion effect, suggesting that a frontal-subcortical loop, the so-called dorsolateral prefrontal-

138 demonstrating that NLRP2 is a member of the subcortical maternal complex (SCMC), an essential cytopl

139 racterized an oscillation between cortex and subcortical modulators that is associated with a serious

140 The remaining patients had subcortical myoclonus (n = 2, 3%) or other patterns (n =

141 The temporal lobe network (TLN), and subcortical network (SCN), and sensorimotor network (SMN

142 ndings provide evidence that reduced CON and subcortical network efficiency play a role in the genera

143 ted, our findings indicate that the cortical-subcortical network generating the alpha oscillation at

144 Subcortical network global efficiency was also significa

145 t that the ventral striatum may be part of a subcortical network that influences conscious experience

146 l L5B neurons establish a widespread cortico-subcortical network via sparse and somatotopically organ

147 natomy of norm compliance across this fronto-subcortical network.

148 mma synchronization to guide the activity of subcortical networks and to regulate feeding behaviour b

149 ntrol protocol, suggesting that cortical and subcortical networks contributed to changes in corticosp

150 ated with atypical development of widespread subcortical networks early in life.

151 that the vmPFC is a key node of cortical and subcortical networks that subserve at least three broad

152 In contrast, for certain subcortical networks, FC emerges along polysynaptic path

153 AS exposure and brain morphometry, including subcortical neuroanatomical volumes and regional cortica

154 ortical astrocytes in regulating cortical or subcortical neuronal synaptogenesis and maturation.

155 ings highlight the integrative properties of subcortical neurons at the cerebellar output stage media

156 al and dorsal anterior cingulate cortex with subcortical nuclei have been the target of neurosurgical

157 confirming age-related increases in several subcortical nuclei that are known to accumulate iron wit

158 s restricted to cortical areas as well as to subcortical nuclei that are under the direct control of

159 bar gray matter and white matter regions and subcortical nuclei were associated with better neurocogn

160 The basal ganglia, a group of subcortical nuclei, play a crucial role in decision-maki

161 d plaques and changes in cortical layers and subcortical nuclei.

162 and prior knowledge of iron accumulation in subcortical nuclei.

163 white matter of the four cerebral lobes and subcortical nuclei/regions with 1.5-tesla proton magneti

164 ue to impairments in the early activation of subcortical orienting mechanisms, which in typical devel

165 port the existence of a phylogenetically old subcortical pathway providing fast, but coarse, threat-r

166 ur findings support the existence of a rapid subcortical pathway that is nonselective in terms of the

167 A fast, subcortical pathway to the amygdala is thought to have e

168 D, possibly due to an abnormal tuning of the subcortical pathway, leading to poor orienting and atten

169 The subcortical pathway, which consists of superior collicul

170 indicates facilitation by the retino-tectal subcortical pathway.

171 ay be supported by alternate cortical and/or subcortical pathways when PER-POR interaction is not ava

172 reflecting indirect cortico-cortical/cortico-subcortical pathways, cannot be reduced to nonspecific a

173 rs of dots, is facilitated in the monocular, subcortical portions of the visual system.

174 ives remission from ADHD, while anomalies in subcortical processes are "fixed," present even in remis

175 inical course of ADHD are separated from the subcortical processes that are not.

176 ate the dynamically interacting cortical and subcortical processes underlying spatial attention, prov

177 PFC neurons that can be distinguished by the subcortical projection targets with which they interface

178 rdination of visual cortex modulation by the subcortical pulvinar nucleus of the thalamus while also

179 These findings identify the subcortical pulvino-amygdalar pathway as a relevant prec

180 l that was Bonferroni corrected for multiple subcortical region comparisons (p < .0063).

181 bilateral insula and 2) greater volume in a subcortical region encompassing the ventral striatum, hy

182 ly inactivated the rhesus monkey amygdala, a subcortical region with distributed and well-defined cor

183 ns of non-newly generated neurons in several subcortical regions (external capsule, claustrum, and am

184 potential across cortical and extrastriatal subcortical regions (t25 = 3.01, P = .01, Bonferroni cor

185 estimates the volume of predefined cortical/subcortical regions and cortical thickness.

186 stly ensheath excitatory axons connecting to subcortical regions and distant cortical areas.

187 al areas and their reciprocal interplay with subcortical regions and hormonal systems.

188 ly as the retina and the mechanisms of OS in subcortical regions are much less well understood.

189 ll, the results implicate right temporal and subcortical regions as the crucial neural substrate for

190 ith fine anatomical division of cortical and subcortical regions associated with human neuropsychiatr

191 Hemifield tuning in cortical and subcortical regions emerges from an opponent hemispheric

192 ReHo changes in several subcortical regions in the electro-acupuncture group, an

193 nges in glutamate levels across cortical and subcortical regions in young healthy individuals and one

194 leus as a hub linking the visual cortex with subcortical regions involved in the initiation and contr

195 leus as a hub linking the visual cortex with subcortical regions involved in the initiation and contr

196 a highly specialized system and suggest that subcortical regions may play a vital role in routing fac

197 ical regions and even to other extrastriatal subcortical regions not previously considered to be "hyp

198 K-6240 showed no displaceable binding in the subcortical regions of human AD brain slices and in the

199 network-wide bursts in diverse cortical and subcortical regions of mammalian brain.

200 iability in gene expression profiles between subcortical regions of typically developing brains.

201 Across the subcortical regions studied by ENIGMA, gene expression p

202 to the identification of a network of fronto-subcortical regions that underpins this ability.

203 We also explored the laterality of subcortical regions to identify characteristic similarit

204 The volume ratio between these cortical and subcortical regions was found to partially mediate the r

205 espread cerebral cortical, white matter, and subcortical regions were analyzed using region of intere

206 ) integrates sensory input from cortical and subcortical regions, a function that requires marked syn

207 In contrast, subcortical regions, especially the thalamus, show highe

208 actions between widespread cortical regions, subcortical regions, including the striatum, influence c

209 network for number processing also includes subcortical regions, like the putamen with connections t

210 t brainstem ARAS structures and 105 cortical/subcortical regions.

211 ons (i.e., layers V-VI) favor connections to subcortical regions.

212 amical interactions between specific distant subcortical regions.

213 These diametric patterns extended into subcortical regions: 22q-dup carriers had a significantl

214 We examined the contribution of lower-order subcortical representations to behavioral responses to t

215 mined layer to the factors shaping the human subcortical response to speech sounds.

216 stopping process is enhanced by the cortico-subcortical reverberatory dynamics underlying persistent

217 Greater functional connectivity in parietal-subcortical reward circuitry predicted greater PGBI-10M

218 e control areas (prefrontal cortex, PFC) and subcortical reward-related regions (nucleus accumbens, N

219 We propose that that the "coarseness" of the subcortical route may be better reframed as "generalized

220 vidence from computational modeling that the subcortical route plays a generalized role in visual pro

221 dala first receives visual input via a rapid subcortical route that conveys "coarse" information, nam

222 n reported, there is mounting evidence for a subcortical saliency mechanism, which pre-dates the evol

223 Novel subcortical shape analysis revealed greater radial dista

224 However, these subcortical signals are much weaker than those generated

225 ethod harnessing normative scaling rules for subcortical size and shape in humans, which we derive he

226 we show here that it is difficult to resolve subcortical sources because distributed cortical activit

227 ivity is spatially sparse, both cortical and subcortical sources can be resolved with M/EEG.

228 r evoked potentials elicited by cortical and subcortical stimulation of corticospinal axons (MEPs and

229 ials (MEPs) elicited by cortical, but not by subcortical, stimulation were more suppressed during pow

230 lectively prevented the migration of SD into subcortical striatal and hippocampal regions in the R192

231 ined MI-BCI and tDCS intervention in chronic subcortical stroke patients with unilateral upper limb d

232 atients in the Secondary Prevention of Small Subcortical Strokes (SPS3) trial and to assess their rel

233 mic coding in an evolutionarily ancient deep subcortical structure that is traditionally viewed as a

234 , it is unclear how mPFC projections to each subcortical structure, as well as projections between BL

235 These fibers course through a subcortical structure, the striatum, and share important

236 We assessed the volumes of eight subcortical structures (nucleus accumbens, amygdala, cau

237 t retrograde tracer injections into multiple subcortical structures allow identifying the long-range

238 me was to assess case-control differences in subcortical structures and intracranial volume through p

239 maturation delay theory for ADHD to include subcortical structures and refute medication effects on

240 trograde tracing identified the cortical and subcortical structures belonging to each network.

241 tic fields generated by neuronal activity in subcortical structures can be recorded noninvasively, us

242 We demonstrate that neurodegeneration of subcortical structures in Alzheimer's disease is not sym

243 The involvement of subcortical structures in representing numerical quantit

244 racterizing electrophysiological activity in subcortical structures in the human brain.

245 r a developmentally sensitive period whereby subcortical structures in young neonates may be most vul

246 s revealed FEF connections with cortical and subcortical structures participating in higher order vis

247 Subcortical structures play a critical role in brain fun

248 plasticity of the OKR is thought to involve subcortical structures such as the cerebellum and vestib

249 ity, prefrontal projection neurons innervate subcortical structures that contribute to reward-seeking

250 tation of information from sensory organs or subcortical structures to the cortex.

251 g these circuits at adulthood, especially in subcortical structures, appears to be much less.

252 In subcortical structures, eyelid closures were associated

253 atio, thus optimizing visualization of small subcortical structures.

254 tween populations of neurons in cortical and subcortical structures.

255 ted "hedonic circuit" involving cortical and subcortical structures.

256 rontal cortex while PD- had GM reductions in subcortical structures.

257 al variation in the shape of seven bilateral subcortical structures: the nucleus accumbens, amygdala,

258 Freesurfer automated segmentation of the subcortical surface was carried out to measure thalamic

259 the eye-regions on all the components of the subcortical system altogether has never been performed.

260 The subcortical system is particularly important as it shape

261 attention but reduced cingulo-opercular and subcortical system segregation with increasing cognitive

262 h ASD show abnormally high activation in the subcortical system, which may be at the basis of their e

263 arameter space that allows predicting a PT's subcortical target region, without the need to inject mu

264 the in vivo electrophysiology of PTs, whose subcortical target regions are identified.

265 sensory stimulation, reflect the respective subcortical target regions of PTs.

266 on of L5B giant boutons in the POm and other subcortical targets is not known, and therefore it is un

267 treatments targeting mu-ORs and specific PFC subcortical targets will be explored.

268 , secondarily in corticofugal fibres and the subcortical targets with which they make monosynaptic co

269 d reciprocates connections with cortical and subcortical targets.

270 ed and are typically not capable of reaching subcortical targets.

271 eep-layer prefrontal neurons that project to subcortical targets.

272 structure and activity can predict specific subcortical targets.

273 ional actions, executive control shifts from subcortical to prefrontal structures during pubertal dev

274 rior temporal lobe; or (2) the presence of a subcortical U-fibre lesion or (3) a Dawson's finger-type

275 ntia (OR 1.8, 95% CI 1.2-2.7, P = 0.002) and subcortical vascular cognitive impairment (OR 2.4, 95% C

276 lia was associated with clinically diagnosed subcortical vascular cognitive impairment and negatively

277 y-six patients (Alzheimer's disease n = 110; subcortical vascular cognitive impairment n = 116) with

278 lipoprotein E varepsilon4 allele; those with subcortical vascular cognitive impairment were more like

279 n the basal ganglia would be associated with subcortical vascular cognitive impairment.

280 between clinically diagnosed Alzheimer's and subcortical vascular cognitive impairment.

281 r proper amyloid PET analysis, especially in subcortical vascular dementia (SVaD) patients.

282 impairment patients (45 amnestic type and 72 subcortical vascular type), from which 83 patients recei

283 over the existence and function of a direct subcortical visual pathway to the amygdala.

284 umans, mirroring known relationships between subcortical volume and TBV among species.

285 rticipants with overlapping genetic data and subcortical volumes (N = 978) and WM measures (N = 816).

286 ally significant associations between either subcortical volumes or WM microstructure, and polygenic

287 We show that all three subcortical volumes scale sublinearly with TBV among hea

288 hilst we found no significant differences in subcortical volumes, significant reductions were found i

289 al (beta = -0.08, P = .03) temporal regions, subcortical white matter (beta = -0.13, P = .02), and oc

290 her cerebellar gray matter (SUVRCB) or whole subcortical white matter (SUVRWM) as the reference.

291 er [CGM], whole cerebellum [WCER], pons, and subcortical white matter [SWM]) were studied.

292 Subcortical white matter injury is often accompanied by

293 Conclusion Subcortical white matter ischemic lesion locations and s

294 dystrophic calcifications in the cortex and subcortical white matter, with associated cortical displ

295 r to posterior, and from deep to superficial subcortical white matter.

296 ering neurological diseases that involve the subcortical white matter.

297 icantly associated with presence of anterior subcortical WMH patches (OR 3.647, 95% CI 1.681 to 7.911

298 at it emerges from spatial nonlinearities of subcortical Y cells.

299 at have spatial nonlinearities like those of subcortical Y cells.

300 d responses to gratings, similar to those of subcortical Y cells: they respond at the second harmonic