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1 he rotational conformational state of its 2B subdomain.
2 nduce its degradation dependent on the NS5A1 subdomain.
3 n a reliable tagger not tied to any specific subdomain.
4 onserved segment adjacent to the helical HID subdomain.
5 eEF1A interacts with Rho1p via a C-terminal subdomain.
6 ry genes operating across the border of each subdomain.
7 nges involving a large rotation of an entire subdomain.
8 ream protein partner bound to the EIN(alpha) subdomain.
9 on led to disruption of Hh signaling in this subdomain.
10 ycan and have mapped the binding to its beta subdomain.
11 s that have interrupted the closure of the N-subdomain.
12 nd the integrin-binding properties of its F3 subdomain.
13 a summary narrative synthesis by domain and subdomain.
14 ses indicated that it can insert into the F2 subdomain.
15 structural parts, called the alpha- and beta-subdomain.
16 wo unc-13 (Unc13) isoforms to presynaptic AZ subdomains.
17 individual arrangement of the characteristic subdomains.
18 guing that they bud continuously from stable subdomains.
19 (229-280), P2 (281-447), and P1-2 (448-567) subdomains.
20 terminal, alpha-helical, and alpha/beta-core subdomains.
21 omain is divided into the P1-1, P2, and P1-2 subdomains.
22 hically by sequential stabilization of their subdomains.
23 ted "puncta" positioned upon raised membrane subdomains.
24 F(0) for energy transduction between the two subdomains.
25 hain particles contain distinct cross-linked subdomains.
26 distinct functional properties of conserved subdomains.
27 ut exploring the modulatory effects of these subdomains.
28 nd gamma-catenin reside within its F1 and F3 subdomains.
29 etermined the main input structures to these subdomains.
30 sphatidylinositol synthase (PIS)-enriched ER subdomains.
31 omization of Re-chains and formation of ReS2 subdomains.
32 iation with different cellular membranes and subdomains.
35 HipA forms dimers in these assemblies via N-subdomain-1 interactions that occlude their active sites
37 291, 324, and 328 were located at protruding subdomain 2 (P2) of VP1, which may influence virus bindi
38 We have identified an interface on IFNAR1-subdomain-3 that is differentially utilized by IFN-beta
39 r to those of other beta-CoVs, the insertion subdomain adopts a novel fold, which is largely invisibl
41 hat PINK1 recruits Parkin onto mitochondrial subdomains after actinonin-induced mitochondrial proteot
42 yIIC reveals a novel fold, consisting of two subdomains alphaA-beta1-beta2 and beta3-beta4-alphaB-bet
43 his pocket is located in the polymerase palm subdomain and conserved across the four serotypes of den
44 firm the mechanosensory role of the talin R3 subdomain and exclude the possibility that the observed
46 of the membrane-binding functions of the F2 subdomain and the integrin-binding properties of its F3
47 , which reveals two structurally independent subdomains and an unprecedented dimer centred at the sig
48 ndapin colocalize with Past1 in distinct SSR subdomains and collapse into Amphiphysin-dependent membr
50 sphorylation sites across cytoplasmic kinase subdomains and to derive a statistically significant seq
52 rivation and several deprivation domains and subdomains) and the 2011 England and Wales census demogr
53 hagy-initiation complex, the PIS-enriched ER subdomain, and ATG9A vesicles together initiate autophag
54 he rotational conformational state of its 2B subdomain, and its helicase activity has been correlated
55 the secondary structure of the various mucin subdomains, and glycosylation patterns along individual
57 folds the locus into several 250- to 400-kb subdomains, and Pax5 further compacts the 2-Mb region th
58 condary structural element in the peripheral subdomain appears to be the key determinant in observed
62 Here, we show how the boundaries of the CB subdomains are established, and thus ascertain the desig
63 d that topologically associating domains and subdomains are fundamental building blocks of the three-
66 recise localization of SNX27 at an endosomal subdomain as well as for recycling of SNX27-retromer car
68 esults in repositioning of the tetrathiolate subdomain away from the rest of the catalytic domain, th
70 ocesses, we analysed the function of a thumb subdomain beta-hairpin using initiation, elongation and
71 ocesses, we analysed the function of a thumb subdomain beta-hairpin using initiation, elongation, and
72 ed that the linker in H. pylori MotB forms a subdomain between the plug and the C-terminal domain, th
73 CUP expression becomes cleared from boundary subdomains between petal primordia, most likely contribu
74 cer cells reveals several unique features of subdomain boundary as compared to domain boundary, inclu
76 ing of SV40 from BAP31 traps the virus in ER subdomains called foci, which likely serve as depots fro
79 rent types of neighbouring cells, then these subdomains can become polarised in opposite directions.
80 domain consists of two functionally distinct subdomains, CC1 (amino acids (aa) 414-530) and CC2 (aa 5
81 nsity in three distinct ways: delaying alpha-subdomain compaction, facilitating beta-strand intercala
82 more stable against unfolding than a smaller subdomain comprised of a short alpha-helix and three-str
83 ic interactions between two semi-independent subdomains connected by an allosteric switch at Asp52(2.
84 2 subdomain is likely an insertion in the P1 subdomain; consequently, the P domain is divided into th
87 suppresses the segregation of mitochondrial subdomains containing DeltaOTC, it does not decrease the
90 so contains an essential GNRA tetraloop in a subdomain (d10c) that is homologous to poliovirus dIVc.
92 stepwise destabilization of the talin rod R3 subdomain decreases cellular traction force generation,
93 letion, mutation, or replacement by the same subdomain derived from other alphaviruses has strong neg
96 oordinated by an independent movement of two subdomains, dsRBD1 and dsRBD2, in which the diffusion di
100 f these events was critical; premature alpha-subdomain folding prevented subsequent core formation.
101 loped for monitoring the rates of individual subdomain folding transitions in situ, in the context of
102 hymena group I ribozyme, the separated P5abc subdomain folds to local native secondary and tertiary s
104 e ER-mitochondria interface, and it contains subdomains for mitochondrial as well as ER localization.
105 lity is the motion of the polymerase fingers subdomain from an open to a closed conformation upon bin
112 find that a specific portion of the helical subdomain (HD) of the catalytic domain rapidly unfolds w
113 (TGN) is a central hub divided into multiple subdomains hosting distinct trafficking pathways, includ
114 esentation of the animal kingdom ontological subdomain: how the brain represents the perceived threat
115 similarity to the human topoisomerase I core subdomains I and II (30-IXAla, 30-620A, and 30-622A).
116 Additionally, homologous substitutions in subdomains IB and IIB of Ssa1 caused defects in collabor
117 that several variants with substitutions in subdomains IB and IIB of the DnaK NBD were defective in
118 bserved that GrpE, which also interacts with subdomains IB and IIB, inhibited the interaction between
125 iring interaction between the apical loop of subdomain IIId in the IRES and helix 26 in 18S rRNA.
127 its pairwise arrangement with the companion subdomain in each brace of protomers of the DnaB hexamer
129 e synthesized, to which pre- or postsynaptic subdomains in a given neuron type they localize, and whe
134 f the full-length TR pseudoknot and isolated subdomains in Oryzias latipes (Japanese medaka fish), wh
136 lipid rafts have been proposed to be unique subdomains in the plasma membrane that are critical for
141 kindlin 3 (K3) chimeras revealed that the F2 subdomain, in particular its C-terminal part, is crucial
142 nd the physicochemical properties of peptide subdomains, including the number and spatial location of
143 h neighboring substructures, indicating that subdomain interactions can stabilize alternative folds o
144 fer intermediate, brings the EIN(alpha/beta) subdomain into close proximity to the C-terminal dimeriz
147 Compartmentalized signaling in dendritic subdomains is critical for the function of many central
149 ognition is mediated via a four-helix bundle subdomain located in the cytoplasm, which functions as t
150 dures, we provide a structural model for the subdomain-mediated tetramer/tetramer interaction via "cr
151 minus of the beta2AR with the GRK5 RH bundle subdomain, membrane-binding surface, and kinase catalyti
152 so suggest that the vinculin-binding domain (subdomain MI) is intrinsically much less stable than the
154 atalytic prim fold domain, but with a unique subdomain not found in the archaeal and bacterial primas
155 -terminal domain bears closest homology to a subdomain of 6-phosphofructokinase, an important enzyme
157 Mutagenesis studies showed that an extra subdomain of about 12 amino acids contribute to C4 oxida
159 mmetry and spindle pole movement towards the subdomain of cortical ER, whereas locally increasing mic
163 ly ascidian embryos possess a large cortical subdomain of endoplasmic reticulum (ER) that causes asym
164 ision.Early ascidian embryos have a cortical subdomain of endoplasmic reticulum (ER) that controls as
165 depolymerase Kif2 is localized to a cortical subdomain of endoplasmic reticulum that is involved in a
166 e rotational conformational states of the 2B subdomain of fluorescently labeled UvrD and their rates
170 ce analysis of the C-terminal part of the F2 subdomain of K3 suggests that insertion of a variable gl
172 a potential targeting function of the GAPex subdomain of neurofibromin that is present in all known
176 ntermediate in tertiary folding of the P5abc subdomain of the 'Tetrahymena' group I intron ribozyme.
177 are associated with functions localized to a subdomain of the endoplasmic reticulum (ER), known as mi
178 depolymerase Kif2 is localized to a cortical subdomain of the ER that is involved in asymmetric spind
181 is caused by specific interactions between a subdomain of the non-alpha-helical N terminus (residues
182 acts with a novel binding pocket in the palm subdomain of the RdRp and exerts a promising activity ag
185 ues 403 and 404 (both Asp --> Ala) in the 2B subdomain of UvrD (uvrD303) confers an antimutator and U
186 ata demonstrate that the very amino-terminal subdomain of Venezuelan equine encephalitis virus capsid
187 al development, cells rearrange and when two subdomains of a single cell have different types of neig
190 b-meta-analyses were conducted in functional subdomains of emotion processing; in cool and hot execut
191 While the structure of the core and SD-1 subdomains of HKU1 are highly similar to those of other
192 sis on the sequence conservation patterns of subdomains of KCNQ1 and the distribution of pathogenic v
193 in binding site resides within the F1 and F3 subdomains of Kindlin-2 but not the integrin binding sit
194 he larval epidermis of Drosophila, different subdomains of one cell can have opposite polarities.
195 ode sequences, which target them to specific subdomains of the cortical endoplasmic reticulum in deve
196 etory protein trafficking by assembling onto subdomains of the endoplasmic reticulum (ER) in two laye
197 e FYVE-containing protein 1 (DFCP1)-positive subdomains of the endoplasmic reticulum (ER), distinct f
200 domain of FtsA in the cytoplasm and to small subdomains of the FtsB and FtsL proteins in the periplas
203 energetic and mechanical changes within the subdomains of the nucleotide binding domain (NBD) of the
206 rbon atoms are enriched in secretory vesicle subdomains of the TGN and are critical for de novo polar
207 mbinant proteins corresponding to particular subdomains of TspB were found to have human IgG Fcgamma-
208 cytic marker FM4-64 revealed the presence of subdomains on the apical membrane characterized by exten
209 dCACHE family, a structure with two PAS-like subdomains, one membrane-proximal and the other membrane
211 ral features: an additional novel alpha+beta subdomain placed close to the putative transmembrane alp
212 ease-causing mutations indicate that the two subdomains play pivotal but distinct roles and that the
213 spots are significantly smaller than a Golgi subdomain positive for scaffolding protein AKAP450, whic
214 136 (I136N) and Thr for Ile-142 (I142T) in a subdomain previously named the helical hairpin in the NT
215 HTLV-1 CA CTD, indicating that the HTLV-1 CA subdomains provide distinct contributions to Gag-Gag oli
217 sly suggested, and propose that a network of subdomains regulates diverse heterochromatin functions.
221 S-CoV Sia-binding activity was assigned to S subdomain S1(A) When multivalently displayed on nanopart
224 the very amino-terminal VEEV capsid-specific subdomain SD1 is a critical player in the particle assem
226 particle assembly proceeds only when the two subdomains, SD1 and SD2, are derived from the same alpha
227 Notably, introducing disulfide bonds between subdomains SD2 and SD3 modulated IFN binding and activit
228 plays a bi-modular structure composed of two subdomains separated by a flexible serine-rich linker.
229 ther demonstrate in vivo that the N-terminal subdomain serves as a pedestal for the C-terminal subdom
230 entify TZ components and localize them to TZ subdomains, showing that the Bardet-Biedl syndrome compl
233 rates of folding of two or more neighboring subdomain structures using a single mutant to facilitate
234 es exist within the RGS homology (RH) bundle subdomain, substrate-binding site, and kinase C-tail.
235 ither enrichment in or specificity to apical subdomains such as emerging flower primordia, and a larg
236 iary structural changes in the alpha-helical subdomain suffice to account for the observed conformati
237 catalytic site and a proline-rich C-terminal subdomain suggest that this protein may have a distinct
238 flexibility is evident throughout the first subdomain, suggesting that the HlyIIC structure may have
241 We identify five residues in the insertion subdomain that are critical for binding of neutralizing
242 een N-terminal and C-terminal regions of the subdomain that are important in the structural changes r
243 ra, Chm7, is recruited to a nuclear envelope subdomain that expands upon inhibition of NPC assembly a
244 fied a flexible region within the rigid beta-subdomain that gives way under load, thus opening up the
245 glycerol from PA, targets a nuclear membrane subdomain that is in contact with growing lipid droplets
246 CR extracellular domains contain a conserved subdomain that mediates self-cleavage proximal to the st
247 Da CagA protein revealed a stable N-terminal subdomain that was used in a yeast two-hybrid screen tha
248 terobacteriaceae and folds into two distinct subdomains that associate with different parts of the ca
249 teins consist of three sequential beta-sheet subdomains that bind to specific carbohydrates to perfor
251 partition into the proximo-distally oriented subdomains that convey positional information to these d
252 ochromatin domain, most localize to discrete subdomains that display dynamic localization patterns du
254 as anatomical value for revealing functional subdomains that have not been classified by conventional
256 that it can be divided into three functional subdomains that roughly correspond to the three conserve
257 scription factor co-associations and genomic subdomains that suggest shared patterns of regulation, a
258 Moreover, apPOL has an additional N-terminal subdomain, the absence of which severely diminishes its
259 Here, we show that the distal-most of these subdomains, the distal cap, is marked by expression of t
260 at least partially mapped onto different SC subdomains, the lateral (SCl) and medial (SCm), respecti
261 directly convert into neuroblasts, in an IPC subdomain they generate migratory progenitors by epithel
262 ertoire by establishing protective motifs in subdomain three outside the receptor-binding and dimeriz
263 terminal domain alpha/beta (EIN(alpha/beta)) subdomain to the downstream protein partner bound to the
264 h precise laser microdissections of meristem subdomains to define the molecular signatures of anatomi
265 ngs define the contribution of the three CTD subdomains to the DNA replication activity of E1 in vivo
266 f the motions of the converter and lever arm subdomains to the rest of the protein and b) a rewiring
268 mulations, the reorientation of the MII/MIII subdomains under force may constitute an initial step al
269 r is highly atypical, having a discontinuous subdomain unrelated to a WD40 motif in place of one of i
272 volved stabilizing the modified MBP and OspA subdomains via external interactions with neighboring su
273 able region between protein kinase catalytic subdomains VII and VIII, is a common mechanism for stimu
278 tes ankyrin-G accumulation in distinct spine subdomains, where it differentially regulates NMDA recep
279 a rigid and closed arrangement of the Galpha subdomain, whereas the apo and GDP-bound forms are consi
280 n, ELC1 appears to engage the MyoA converter subdomain, which couples the motor domain to the neck.
281 main serves as a pedestal for the C-terminal subdomain, which determines the ability of MapZ to mark
282 sites of HA are located in the globular head subdomain, which is highly tolerant of amino acid substi
283 s twofold pseudo-symmetric with two globular subdomains, which are structurally similar but functiona
284 RT induces opening of the fingers and thumb subdomains, which increases the dynamic sliding motion o
286 a sharing is non-uniform across neuroscience subdomains, widespread adoption of data sharing practice
287 ch GRAS domain comprises one alpha/beta core subdomain with an alpha-helical cap that mediates hetero
288 "mitochondrial RNA granules," mitochondrial subdomains with an emerging role in the regulation of ge
289 -chain length links lipid composition of TGN subdomains with polar secretory trafficking of PIN2 to a
290 to alter the surfaces and the orientation of subdomains with respect to each other, likely resulting
291 approach, we engineered the sequences of one subdomain within maltose binding protein (MBP, alpha/bet
292 s/Fat system; we show that the polarity of a subdomain within one cell is its response to levels of D
293 ngle-cell analysis, we identified a cellular subdomain within the midhypocotyl, whose expansion drive
294 ensive molecular signatures for the distinct subdomains within AC-type SAMs, an anatomical anomaly wh
295 eld contact network model reveals functional subdomains within RyR2 clusters with distinct sensitivit
296 ting insight into the spatial arrangement of subdomains within the adult neural subventricular zone (
297 d that exhibits a major rearrangement of the subdomains within the C-terminal two-thirds of PB2 (PB2-
298 e insights into the structural properties of subdomains within the full-length vimentin, in particula
299 ozyme's primary amino acid sequence revealed subdomains within the protein that operate either as an
300 These data define the cap and shoulder as subdomains within the repair complex accumulating distin
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