ライフサイエンスコーパス: subgingival

1 ontal pockets with PD of >/=5.4 mm, a single subgingival administration of a 0.4% moxifloxacin gel as

2 y was to test the hypothesis that adjunctive subgingival administration of chlorhexidine gelatin bior

3 Subgingival and peri-implant biofilm samples were collec

4 We hypothesized that the microbiota of subgingival and tongue samples would differ between earl

5 MP Jumpstart data on 24 subjects for saliva, subgingival, and supragingival samples.

6 Alternative regimens using subgingival antimicrobials compared to conventional peri

7 s were randomly assigned to receive a single subgingival application of a 0.125%, 0.4%, or 1.25% moxi

8 tive periodontal pathogens and resistance of subgingival bacteria against moxifloxacin were assessed.

9 obial mouthrinse on levels of representative subgingival bacteria in subjects with mild to moderate p

10 perturbation of gingival epithelial cells by subgingival bacteria interacting through pattern-recogni

11 ion on the prevalence and levels of selected subgingival bacteria using molecular approaches for bact

12 Levels and proportions of 40 subgingival bacteria were determined using checkerboard

13 of local inflammation on the composition of subgingival bacteria, and 3) to understand how inflammat

14 determine the effect on clinical variables, subgingival bacteria, and local immune response brought

15 mographics, PD, clinical loss of attachment, subgingival bacteria, serum hsCRP, interleukin (IL)-1bet

16 cols on salivary nitrite and its relation to subgingival bacteria.

17 bacterium and the most common member of the subgingival bacterial community, were associated with pe

18 , a chronic inflammation driven by dysbiotic subgingival bacterial flora, is linked on clinical level

19 We investigated the prevalence of subgingival bacterial infection with eight species, test

20 ts did not sterilize or substantially reduce subgingival bacterial populations compared to negative c

21 th respect to reduction in probing depth and subgingival bacterial populations.

22 study characterizes the association between subgingival bacterial profile and periodontal parameters

23 Pooled subgingival bacterial samples were collected from 477 de

24 ngival crevicular fluid (GCF) biomarkers and subgingival bacterial species in periodontally healthy s

25 Eikenella corrodens is a commensal subgingival bacterium commonly found in both periodontal

26 y to proliferate within and disseminate from subgingival biofilm (plaque) is central to its virulence

27 s identified by polymerase chain reaction in subgingival biofilm and serum.

28 l role for smoking cessation in altering the subgingival biofilm and suggest a mechanism for improved

29 that SubGPAP is more efficacious in removing subgingival biofilm in moderate-to-deep periodontal pock

30 surface is effective in removing most of the subgingival biofilm in periodontal pockets with an APD <

31 We tested the hypothesis that the subgingival biofilm is compositionally different in curr

32 A 10-species in vitro subgingival biofilm model was exposed to metronidazole (

33 Subgingival biofilm samples from each tooth were analyze

34 studies comparing microbiologic outcomes of subgingival biofilm samples from healthy implants and im

35 Subgingival biofilm samples were obtained, and the level

36 Seven subgingival biofilm samples were taken successively, usi

37 ed to full-mouth periodontal examination and subgingival biofilm sampling (14 sites/patient).

38 Subgingival biofilm specimens from inflamed deep periodo

39 Subgingival biofilm was analyzed regarding 11 periodonto

40 sythia (previously T. forsythensis) in their subgingival biofilm was determined by polymerase chain r

41 VL and the levels of 35 microbial species in subgingival biofilm, adjusted for confounders.

42 olymerase chain reaction on the basis of the subgingival biofilm, and IL-1beta and TNF-alpha were qua

43 of periodontitis; however, its effect on the subgingival biofilm, the primary etiological agent of pe

44 ts the composition of the disease-associated subgingival biofilm, yet little is known about its effec

45 s, C. gingivalis, and D. pneumosintes in the subgingival biofilm.

46 Both marginal and subgingival biofilms in smokers are characterized by ear

47 d by significant changes in the marginal and subgingival biofilms, with a decrease in the abundance o

48 le initial colonization of both marginal and subgingival biofilms, with lower niche saturation than t

49 ine the reproducibility of curet sampling of subgingival biofilms.

50 Root chips that showed no attachment to the subgingival calculus also had no cells attached to the a

51 nfounding factors and effect modification by subgingival calculus and age.

52 Sites with subgingival calculus and bleeding on probing demonstrate

53 ad no significant effect on cLCAL/cPD, while subgingival calculus and bleeding on probing were negati

54 levels, bleeding upon probing, or extent of subgingival calculus comparing subjects assigned to prot

55 e on human gingival fibroblast attachment to subgingival calculus on contaminated root surfaces.

56 attachment of human gingival fibroblasts to subgingival calculus or contaminated root surfaces.

57 associations between bone density, CAL, and subgingival calculus require further research, particula

58 chment to tooth surfaces formerly covered by subgingival calculus than all other groups (P <0.001).

59 ulus deposition over tooth surfaces, and the subgingival calculus that enables the enlargement of the

60 Presence or absence of subgingival calculus was a strong effect modifier.

61 In experiment 2, teeth with subgingival calculus were treated with DHV, VC, scaling

62 In experiment 1, teeth with subgingival calculus were treated with either doxcycycli

63 ans with type 2 diabetes had more supra- and subgingival calculus, an increased extent and severity o

64 Among women without subgingival calculus, there were consistent inverse asso

65 Among women with subgingival calculus, there were no associations between

66 mic bone density and CAL among women without subgingival calculus.

67 separate experiments were performed, both on subgingival calculus.

68 Identification and location of subgingival caries, root fractures, tooth root deposits,

69 poor biologic width resulting from extensive subgingival caries.

70 In multivariate regression models, subgingival colonization of A. actinomycetemcomitans and

71 Periodontitis is caused by subgingival colonizing bacteria in the oral cavity.

72 ed to perform a directed survey of the human subgingival crevice and to isolate bacteria having rod-l

73 ubunit ribosomal RNA genes (SSU rDNA) in the subgingival crevice by using quantitative PCR.

74 rticipate in syntrophic relationships in the subgingival crevice that promote colonization by seconda

75 significantly more effective in reducing the subgingival cultivable microflora in shallow periodontal

76 ts were identified who underwent surgery for subgingival curettage and/or periodontal flap and are co

77 riodontal disease who undergo procedures for subgingival curettage and/or periodontal flap have a rem

78 h severe, generalized periodontitis received subgingival debridement and oral hygiene instructions ea

79 The purpose of this study was to assess the subgingival debridement efficacy of GPAP in periodontal

80 h were stained with 0.5% toluidine blue, and subgingival debridement efficacy was assessed.

81 group (one session of full-mouth ultrasonic subgingival debridement followed 1 week later by Er:YAG

82 (Er:YAG) laser application as an adjunct to subgingival debridement in the treatment of chronic peri

83 Subgingival debridement plus adjunctive SDD reduced deep

84 f oral hygiene instructions, motivation, and subgingival debridement using a piezoelectric instrument

85 ssesses the efficacy of combining full-mouth subgingival debridement with Er:YAG laser application in

86 ollowing a standard course of machine-driven subgingival debridement.

87 onstellatus and Streptococcus intermedius in subgingival dental plaque biofilms may contribute to for

88 acterial DNA in both prostatic secretion and subgingival dental plaque from the same individual.

89 g the restorative phase of treatment, and in subgingival dental plaque of periodontitis patients, ind

90 cter rectus, and Fusobacterium nucleatum, in subgingival dental plaque of pregnant women in the OPT S

91 rimary niche is the anaerobic environment of subgingival dental plaque, but initial colonization of t

92 levels of P. gingivalis and S. cristatus in subgingival dental plaque.

93 y of oral bacterial surfaces and to colonize subgingival dental plaque.

94 tyle within the mixed-species environment of subgingival dental plaque.

95 al flap surgery is frequently used to remove subgingival deposits, yielding consequential reductions

96 ation of the organism from the sites) of the subgingival E. corrodens clonal types between the baseli

97 amined the clonal diversity and stability of subgingival E. corrodens over time.

98 Pure cultures of 47 subgingival E. faecalis clinical isolates were each inoc

99 evealed poor in vitro activity against human subgingival E. faecalis clinical isolates, and would lik

100 developed to facilitate visualization of the subgingival environment as an aid in diagnosis and non-s

101 development of antibiotic resistance in the subgingival flora in either group.

102 No antimicrobial effect on the subgingival flora was detected following treatment with

103 influence the composition of the contiguous subgingival flora.

104 matous, with a propensity toward spontaneous subgingival hemorrhage.

105 ine digluconate, or 7.5% povidone-iodine for subgingival irrigation during SRP.

106 eatment outcome after 12 months of different subgingival irrigation solutions during scaling and root

107 is known of the antibiotic susceptibility of subgingival isolates of these two bacterial species, thi

108 In response to persistent subgingival ligature-mediated challenge, Rac-null mice h

109 ontium in response to periodontitis-inducing subgingival ligatures compared with wild-types.

110 Inflammatory responses to subgingival ligatures, assessed by changes in peripheral

111 entification microarray (HOMIM) was used for subgingival microbial assessment.

112 -mouth clinical measures of extent/severity, subgingival microbial burden by several species, and sel

113 The ability of the subgingival microbial community to induce an inappropria

114 ing cessation altered the composition of the subgingival microbial community, by means of a quantitat

115 ease not accounted for by differences in the subgingival microbial infection.

116 monstrated that smoking cessation alters the subgingival microbial profile; however, the response of

117 ailable data on clinical periodontal status, subgingival microbial profiles, and serum IgG antibodies

118 stic effects of smoking and pregnancy on the subgingival microbiome have never been studied.

119 The subgingival microbiome is largely uncultivated, and ther

120 riodontal therapy and smoking cessation, the subgingival microbiome is recolonized by a greater numbe

121 The subgingival microbiome was evaluated via 16S rRNA gene s

122 EMD treatment predictably alters a dysbiotic subgingival microbiome, decreasing pathogen richness and

123 or smokers in order to effectively alter the subgingival microbiome.

124 Assessment of the rat subgingival microbiota after RvE1 treatment revealed mar

125 ncing was used to compare the composition of subgingival microbiota and establish correlations betwee

126 f smokers; however, long-term changes in the subgingival microbiota following the use of these drugs

127 gates HGF expression and its relationship to subgingival microbiota in medically healthy individuals

128 This comprehensive analysis of the subgingival microbiota in patients with PLS used 16S rib

129 The subgingival microbiota in PLS is diverse.

130 Our results suggest a complexity of subgingival microbiota not seen previously.

131 The subgingival microbiota observed in patients with new-ons

132 ective of this study was to characterize the subgingival microbiota of African-American children with

133 This study compares the changes to the subgingival microbiota of individuals with "refractory"

134 on-periodontal-related microorganisms in the subgingival microbiota of individuals with HIV.

135 e and number of periodontal pathogens in the subgingival microbiota of smokers versus never-smokers w

136 t in patients with a metronidazole-sensitive subgingival microbiota on the clinical parameters of CAL

137 The subgingival microbiota profile in patients with new-onse

138 translocation of periodontal pathogens from subgingival microbiota to the bloodstream and then to at

139 The composition of the subgingival microbiota was characterized by 16S rDNA seq

140 he relationships among these biomarkers, the subgingival microbiota, and the clinical parameters of p

141 major role in shaping the composition of the subgingival microbiota.

142 The subgingival microflora in patients presenting concurrent

143 val plaque level on the relationship between subgingival microorganisms and the risk of attachment lo

144 udy suggests that the association of certain subgingival microorganisms with CAL changes in relation

145 Scaling and root planing and subgingival minocycline in experimental sites took littl

146 Recent investigations of the human subgingival oral flora based on ribosomal 16S cloning an

147 Treponema denticola is a predominantly subgingival oral spirochete closely associated with peri

148 ily rinsing, the level of each of the target subgingival organisms was significantly lower in the ess

149 antimicrobial sensitivity of enterococci of subgingival origin, this study evaluates the in vitro an

150 Subgingival P. endodontalis levels and serum immunoglobu

151 Subgingival P. endodontalis was defined by checkerboard

152 Subgingival P. endodontalis, its immune response, and se

153 ere found between the presence of individual subgingival pathogens and cancer risk.

154 fect of alcohol consumption on the levels of subgingival periodontal pathogens and proinflammatory cy

155 n vitro antibiotic resistance among selected subgingival periodontal pathogens in patients with CP.

156 h CP in the United States frequently yielded subgingival periodontal pathogens resistant in vitro to

157 rall, 74.2% of the patients with CP revealed subgingival periodontal pathogens resistant to at least

158 Fifteen percent of patients harbored subgingival periodontal pathogens resistant to both amox

159 e significant antimicrobial activity against subgingival periodontopathogens.

160 y failed to observe any adjunctive effect of subgingival placement of chlorhexidine chips after scali

161 clinical examination during which samples of subgingival plaque and buccal epithelial cells were obta

162 n of a mucoperiosteal flap in each quadrant, subgingival plaque and calculus were removed.

163 Marginal and subgingival plaque and gingival crevicular fluid samples

164 Marginal and subgingival plaque and gingival crevicular fluid samples

165 ed at baseline and after 3 and 6 months, and subgingival plaque and sulcus fluid samples were taken f

166 in children the level of DNA-P gingivalis in subgingival plaque and the IgG serum reactivity to P. gi

167 g of the bacterial species present in canine subgingival plaque and their associations with health an

168 a result of the interaction of the host with subgingival plaque bacteria.

169 nse to specific bacterial species within the subgingival plaque biofilm.

170 hod to detect three periodontal pathogens in subgingival plaque collected before treatment and at 2 a

171 ipid extracts derived from diseased teeth or subgingival plaque do not contain free lipid A constitue

172 Microbiologic differences were found in subgingival plaque for patients with DG and pGI.

173 t pockets in each sextant; pooled supra- and subgingival plaque from another six randomly selected, l

174 Subgingival plaque from deep sites of current and never-

175 Subgingival plaque from diseased sites strongly activate

176 laser on titanium surfaces contaminated with subgingival plaque from patients with peri-implantitis a

177 non-surgical periodontal therapy: supra- and subgingival plaque from the deepest pockets in each sext

178 Subgingival plaque from three healthy and three disease

179 cies level of these organisms recovered from subgingival plaque has been hampered by the lack of a re

180 nt for incorporation of these organisms into subgingival plaque in the human oral cavity.

181 [MMP]-8, elastase, and sialidase) in GCF and subgingival plaque levels of Porphyromonas gingivalis, T

182 Changes in individual species levels in subgingival plaque microbiota were not detectable; howev

183 strain D11S-1, which was recovered from the subgingival plaque of a patient diagnosed with generaliz

184 The same strain was detected in the subgingival plaque of the patient but not in her vaginal

185 ated with preterm birth and were detected in subgingival plaque of women without clinical levels of i

186 ntal examination was performed, and a pooled subgingival plaque sample was collected from the deepest

187 EBV DNA was detected in 18.5% of subgingival plaque samples (72/390) and in at least one

188 Subgingival plaque samples and periodontal data were col

189 cant differences in bacteria in salivary and subgingival plaque samples between AgP and CP.

190 Subgingival plaque samples collected at baseline and day

191 ase chain reaction analysis was performed on subgingival plaque samples for the detection of A. actin

192 Subgingival plaque samples from 35 patients (healthy and

193 In this study, subgingival plaque samples from both healthy and disease

194 of different bacterial species in saliva and subgingival plaque samples from individuals with aggress

195 ecies biofilms were derived using supra- and subgingival plaque samples from mesio-buccal aspects of

196 Here, saliva, supragingival and subgingival plaque samples from periodontitis patients a

197 Whole saliva and subgingival plaque samples from the deepest pocket of ea

198 We analyzed subgingival plaque samples from women who experienced fe

199 The collection of subgingival plaque samples is the common way for the det

200 Nine subgingival plaque samples per patient were analyzed usi

201 in respect to the combination of supra- and subgingival plaque samples taken from the most affected

202 nt positive correlation between salivary and subgingival plaque samples was detected in patients with

203 The microbiology of subgingival plaque samples was evaluated using DNA check

204 Clinical parameters were recorded, and subgingival plaque samples were analyzed at baseline, pe

205 Subgingival plaque samples were analyzed for Aggregatiba

206 Subgingival plaque samples were analyzed using semiquant

207 Subgingival plaque samples were assessed for counts of 4

208 Baseline subgingival plaque samples were assessed for the presenc

209 Subgingival plaque samples were assessed using immunoflu

210 Among these subjects, 4561 subgingival plaque samples were collected (average of 7

211 Subgingival plaque samples were collected at baseline; 3

212 Gingival tissue and subgingival plaque samples were collected from 19 patien

213 In this survey subgingival plaque samples were collected from 223 dogs

214 Nine subgingival plaque samples were collected from each subj

215 n to clinical measurements and GCF sampling, subgingival plaque samples were collected from four post

216 Microbial species within subgingival plaque samples were identified by human micr

217 Pooled saliva and pooled subgingival plaque samples were injected into pregnant m

218 Two subgingival plaque samples were obtained from each subje

219 GCF and subgingival plaque samples were obtained from healthy si

220 Subgingival plaque samples were obtained from periodonta

221 GCF and subgingival plaque samples were obtained from the mesio-

222 Subgingival plaque samples were obtained pre- and postop

223 Subgingival plaque samples were taken at baseline and 15

224 Subgingival plaque samples were taken from diseased (DD)

225 Subgingival plaque samples were taken from the mesio-buc

226 Subgingival plaque samples were taken from the mesio-buc

227 Subgingival plaque samples were taken, and the presence

228 eeding on probing (BOP), were performed, and subgingival plaque samples were taken.

229 AL) were assessed at the same 12 sites where subgingival plaque samples were taken.

230 The collection of subgingival plaque samples with paper points is time-con

231 In 1,188 subgingival plaque samples, 11 bacterial species were as

232 d A in lipid extracts from diseased teeth or subgingival plaque samples.

233 in the placenta than in the pooled saliva or subgingival plaque samples.

234 Oral infection was assessed from subgingival plaque samples.

235 terial species were detected in salivary and subgingival plaque samples.

236 Multiple subgingival plaque samples/patient (1,057 in total) were

237 t be discussed as a potential alternative to subgingival plaque sampling for microbiologic analysis i

238 Subgingival plaque specimens were detected by PCR with s

239 riodontitis, a combined sample of supra- and subgingival plaque taken from the deepest periodontal po

240 Subgingival plaque was collected at baseline, and 3, 6,

241 Subgingival plaque was collected from 22 smokers at the

242 Subgingival plaque was collected from 44 systemically an

243 probing, and plaque index were measured, and subgingival plaque was collected from LAgP diseased and

244 Subgingival plaque was collected from three healthy and

245 Subgingival plaque was collected with sterile paper poin

246 A heavily diluted sample of subgingival plaque was inoculated onto culture plates su

247 Subgingival plaque was sampled at baseline (13 to 16 wee

248 est pockets in each quadrant were probed and subgingival plaque was sampled from 1,043 consecutive ne

249 In 50 patients with periodontitis, subgingival plaque was sampled from the deepest pocket o

250 regatibacter actinomycetemcomitans levels in subgingival plaque were analyzed by quantitative real-ti

251 Clinical data and samples of subgingival plaque were collected at baseline, 45 days a

252 Gingival crevicular fluid (GCF) and subgingival plaque were collected from 77 patients at th

253 rganisms are frequently observed together in subgingival plaque with the spirochetes localized to the

254 s included a periodontal examination; blood, subgingival plaque, and crevicular fluid specimen collec

255 dontitis, is abundant at the leading edge of subgingival plaque, where it interacts with gingival epi

256 ion to the highly proteolytic environment of subgingival plaque, which is exposed continually to an a

257 Subgingival plaque-coated titanium disks with a moderate

258 rrelated with the number of P. gingivalis in subgingival plaque.

259 es in the frequency of bacteria in serum and subgingival plaque.

260 h the sequences amplified from the patient's subgingival plaque.

261 ance of causative/over other bacteria in the subgingival plaque.

262 sythia, but not A. actinomycetemcomitans, in subgingival plaque.

263 h the levels of key periodontal pathogens in subgingival plaque.

264 givalis and Tannerella forsythensis colonize subgingival plaques of mammals, whereas several other Ba

265 Subgingival plaques were analyzed for the presence of 18

266 in reducing clinical parameters of LAgP and subgingival presence of JP2 in diseased and healthy site

267 the levels of plaque bacteria suggests that subgingival recolonization was occurring.

268 tis) HN019 was topically administered in the subgingival region of MFMs on days 0, 3, and 7.

269 In control teeth, virtually all subgingival root surfaces were stained.

270 Subgingival S. constellatus and S. intermedius exhibited

271 gnosed with severe chronic periodontitis had subgingival samples harvested from four sites (the deepe

272 ngue samples was less sensitive than that of subgingival samples in detecting periodontal species, an

273 ans was demonstrated in vascular, blood, and subgingival samples in one of 36 patients.

274 Subgingival samples were collected from two sites (probi

275 Before treatment, pooled subgingival samples were obtained from the five deepest

276 T. forsythia, or C. rectus) were detected in subgingival samples, with a prevalence rate of 72.2%, 47

277 annerella forsythia) in vascular, blood, and subgingival samples.

278 a reliable and reproducible method to obtain subgingival samples.

279 ost subgingival species were associated with subgingival samples.

280 ed a vascular lesion, a blood sample, and 36 subgingival samples.

281 After baseline subgingival sampling, 37 qualifying subjects rinsed with

282 Intervention trials, including subgingival scaling and/or root planing, were systematic

283 g adults with chronic periodontitis received subgingival scaling for 60 minutes.

284 This study aimed to determine whether subgingival scaling resulted in rapid changes in plasma

285 iodontitis patients undergoing an episode of subgingival scaling show a significant elevation in circ

286 temic antibiotics or with plaque control and subgingival scaling significantly reduces CRP levels aft

287 ent and CMV was rarely present in individual subgingival sites affected by chronic periodontitis.

288 rease in microbial diversity was observed in subgingival sites of ailing implants, compared with heal

289 Subgingival sites were sampled every 6 months to assess

290 eriodontitis patients and were restricted to subgingival sites with periodontal disease.

291 to periodontal breakdown in heavily infected subgingival sites, particularly in patients responding p

292 explain the persistence of this organism at subgingival sites.

293 ade the host defence system and colonize the subgingival space.

294 aim of the present study is to analyze which subgingival species are associated with SUP in patients

295 ered in associations with sample sites; most subgingival species were associated with subgingival sam

296 of 33 S. constellatus and 17 S. intermedius subgingival strains, each recovered from separate patien

297 was developed to aid in the visualization of subgingival structures and to improve the diagnosis and

298 al crevicular fluid (GCF) and a selection of subgingival/submucosal plaque bacteria from clinically h

299 CAL, and significantly reduced the amount of subgingival Tf and Td.

300 -time visualization and magnification of the subgingival tooth root surface, aiding in the location o