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1 (including cisplatin and multidrug-resistant sublines).
2 or and in the differentiation-resistant KG1a subline.
3 n of this transcript in the metastatic AT6.1 subline.
4 enerate gene signatures associated with each subline.
5 s increased in an androgen-independent LNCaP subline.
6 relaxin is overexpressed in the LNCaP-R273H subline.
7 s in both vector-alone and Ku86-complemented sublines.
8 blines than in the Ku86-complemented XR-V15B sublines.
9 n of the locus were detected between the two sublines.
10 the Me32a cells than in the MeMNK and MeWND sublines.
11 ut not in the K-ras-disrupted HCT116-derived sublines.
12 mulated or differentiating agent-treated Nb2 sublines.
13 regard to prion susceptibility in tumor cell sublines.
14 n vitro model of MART CTL-resistant melanoma sublines.
15 the expression of vitiligo between SL and BL sublines.
16 lantation of both parental cells and the MDR sublines.
17 including cisplatin- and multidrug-resistant sublines.
18 three drugs were also measured in the HCT116 sublines.
19 n in the uncloned parental cultures for both sublines.
20 cer, we have established docetaxel-resistant sublines.
21 t has been previously reported for these MEC sublines.
22 sistant sublines relative to their sensitive sublines.
23 y aberrations that were not found in the T/F-sublines.
24 terns that were distinct from those of the U-sublines.
25 nsfected into novel PCFT(+) and PCFT(-) HeLa sublines.
26 ases, including 3 derived from highly inbred sublines.
27 lar levels in RA and PsA SM lining layer and sublining.
28 oth patient groups, but lower in PsA than RA sublining.
29 Heterozygous transgenic rats, including P23H sublines 2 and 3 and S334ter sublines 4 and 9, were rear
32 including P23H sublines 2 and 3 and S334ter sublines 4 and 9, were reared in dim cyclic light or in
33 e human breast cancer cell line, MDA-MB-231 (subline 4175) and a noninvasive breast epithelial cell l
34 both VES and alpha-TEA can induce A2780 and subline A2780/cp70 ovarian cancer cells to undergo DNA s
37 uired the highly permissive Huh-7.5 hepatoma subline and adaptive amino acid substitutions in both NS
38 of 3 in methotrexate-resistant CCRF-CEM cell sublines and metabolite protection studies implicated DH
41 um, as activated T cells migrate through the sublining and lining layer, T cell-derived IL-2 may acti
43 tories' wild type Myxococcus xanthus DK1622 "sublines" and sequenced each to determine if they had ev
44 (T-series sublines) or fulvestrant (F-series sublines) and sublines unselected by drugs (U-series).
45 the clonogenic survival of HSL2 (Rho+, HeLa subline), and its derivative cell line lacking mitDNA (R
46 mals bearing EL-4 or EG.7 (an OVA-expressing subline), and repetitively imaged by microPET over sever
47 cing identified 29 variants between the nine sublines, and eight had at least one unique variant with
48 aneously, each line was represented by three sublines, and seeds were equal in age, these estimates a
49 ency and size of GLFG bodies vary among HeLa sublines, and we find that an increased level of Nup98 i
50 and activation of leukocytes in the synovial sublining, and the formation and behavior of the hyperpl
52 both c-Kit and tryptase, accumulated in the sublining area of proliferating synovial tissue from RA
54 The establishment of a series of tumorigenic sublines based on this parental cell line is described.
57 Historically, Swiss Webster mice of the CFW subline, both inbred and random-bred stocks, have been c
58 f gene expression between parental cells and sublines by genome-wide cDNA microarray analysis reveale
59 We have generated SLPI-ablated epithelial sublines by stably transfecting the Ishikawa human endom
60 ia(AR) (a MiaPaCa2-derived anoikis-resistant subline) by culture in poly-2-hydroxyethylmethacrylate-c
61 localized to the nucleus, whereas in its AI subline C4-2, FlnA failed to cleave and remained cytopla
62 CaP cell lines DU145, PC3, LNCaP, and LNCaP sublines (C4, C4-2, and C4-2B), conferred cell growth in
63 e-derived androgen-independent PSA-producing subline, C4-2, we identified two cis-elements within the
66 munization with GM-CSF/IL-12-transfected MDR sublines caused rejection of transplantation of both par
67 ctor-alone, as well as the Ku86-complemented subline cells, indicating both events are initiated by r
68 the immunoreactive protein was localized to sublining cells rather than the intimal lining synoviocy
70 c CEM cell line and two teniposide-resistant sublines, CEM/VM-1 and CEM/VM-1-5 ( approximately 40 and
74 erived from RXRalpha(-/-) embryos and an EMC subline constitutively expressing a dominant negative re
76 liferation of both H520-Cyr61 and H460-Cyr61 sublines decreased remarkably compared with the cells st
77 ive parental line and a stably DDP-resistant subline derived by in vitro selection, resistance to DDP
78 haracterized two novel, PLC-gamma1-deficient sublines derived from the Jurkat T-leukemic cell line.
79 al tumor cell lines, 4T1 and 4T07, which are sublines derived from the parental population of 410.4 c
80 4T07; these cells are thioguanine-resistant sublines derived from the parental population of 410.4 c
82 epothilone-resistant human ovarian carcinoma sublines derived in a single-step selection with epothil
83 rug resistance more fully, a taxol-resistant subline, derived from the human ovarian cancer cell line
86 fected with an hREV1 expression vector and 4 sublines developed in which the hREV1 mRNA level was inc
90 genic human breast cell lines, as well as on sublines differing in their tendency to "home" to differ
91 d that although the Fas-resistant/refractory subline displayed significant metastatic ability, the pa
93 ulture on BM stromal cells plus IL-7, BLIN-3 sublines emerged expressing mu heavy chain and VpreB on
95 were conducted in two pairs of transfectant sublines established from the Ku86-deficient Chinese ham
101 prostate cancer model, androgen-independent sublines expressed higher levels of the HER-2/neu recept
102 pancreatic cancer cell line and its derived subline expressing functional CFTR, we report that MUC4
103 vation of ERKs or causing proliferation in a subline expressing low levels of membrane estrogen recep
106 proliferation of Chinese hamster ovary (CHO) sublines expressing folate receptors (FRs) alpha or beta
109 the synovial lining and was increased in the sublining fibroblasts of patients with RA, compared with
110 A-1 and was observed in multiple independent sublines for both the endogenous alpha IIb gene and tran
113 d fulvestrant, we established drug-resistant sublines from a single colony of hormone-dependent breas
115 pattern of gene expression with the GI-101A subline GI-BRN, which was generated by repeated in vivo
118 CI.1u.Lyp) cohort and Iddm26.2 congenic BBDP sublines has revealed an association of Ptpn22 with T1D.
119 ty between two iso-clonal human colon cancer sublines HCT116 and HCT116b on their ability to undergo
120 2)O(2) were compared in four colon carcinoma sublines: HCT116, HCT116/E6, HCT116+ch3, and HCT116+ch3/
122 murine embryonic fibroblasts (CTR1+/+) and a subline in which both alleles of CTR1 were deleted (CTR1
123 cell line, M160-8, was selected from a HeLa subline in which the RFC gene was deleted and PCFT was h
125 In susceptible aphid genotypes, parasitized sublines infected with Hamiltonella generally showed inc
126 in D(9k) gene by injecting the E14.1 ES cell subline into the C57BL/6 host blastocysts and proved tha
130 he DG75 Burkitt's lymphoma cell line and its sublines (LMP1 transfected and EBV infected), with the h
131 the AS PCa cell line LNCaP and that of an AI subline LNCaP(CS) generated by maintaining LNCaP in medi
132 en independence, we used two human CaP LNCaP sublines: LNCaP(nan), which is androgen dependent (AD),
133 erythrocytes was performed using a RAW 264.7 subline (LR5 cells) and bone marrow-derived macrophages
135 tigen immortalized human prostate epithelial subline M12 by stable transfection with human wild-type
137 vated in RA and osteoarthritis ST lining and sublining macrophages and endothelial cells compared wit
141 an breast epithelial cell line MCF10A with a subline (MCF10A/bcl-2) transfected with the human bcl-2
142 which have low invasive ability, with their sublines MCF7-I4 and MDA-MB453-I4 with high invasive abi
143 Next, we showed that an androgen-refractory subline (MDA-hr) of MDA PCa 2b cells also expressed high
145 ) that do not express either transporter and sublines molecularly engineered to express either ATP7A
146 gher in RA synovium and was localized to the sublining mononuclear cells and the intimal lining.
148 d to produce a heart-specific Cx43-deficient subline ("O-CKO" mice) in which the loss of Cx43 in the
150 membrane molecules on a liver-metastasizing subline of B16 melanoma versus the parental B16-F0 revea
153 signaling pathways of a cetuximab-resistant subline of DiFi colorectal cancer cells (DiFi5) that was
155 peroxide (t-BuOOH)-induced cytotoxicity in a subline of human erythroleukemia K562 cells (K/VP.5) and
162 tively measured these competing effects in a subline of neuroblastoma (N2a) cells and propose a conco
165 cific GTPase-activating protein domain, in a subline of RAW 264.7 cells, and challenged the transfect
166 Characterization of defects in a variant subline of RBL mast cells has revealed a biochemical eve
169 lture, we established a chronically infected subline of the living cells remaining after the death of
170 ys an essential role in lumen formation in a subline of the nonmalignant human breast cell line (MCF1
171 ion was induced in a tumorigenic, metastatic subline of the SV40 large T-antigen immortalized human p
173 ssion after hormone treatment; these include sublines of ALVA-31 as well as the cell lines TSU-Pr1 an
175 FPGS relative to hcFPGS was observed in some sublines of CCRF-CEM with acquired MTX resistance sugges
176 genes were methylated in both the SL and BL sublines of chickens; therefore, methylation does not ap
179 ing immunocompromised mice and highly inbred sublines of Massachusetts General Hospital major histoco
181 phic markers; (2) the generation of congenic sublines of mice by repeated backcrossing of CAST with B
182 phenotype of Darc-knockout mice and congenic sublines of mice carrying small chromosomal segments fro
183 neoplastic transformation in three different sublines of NIH 3T3 cells and multiple clonal derivative
184 nsgenic RIP-Tag lines, and three polymorphic sublines of one, enabled us to investigate the effects o
188 Here, we used organ-specific metastatic sublines of the MDA-MB-231 human breast cancer cell line
189 taneous fusion between bone- and lung-tropic sublines of the MDA-MB-231 human breast cancer cell line
190 s M4A4 and NM2C5 are spontaneously occurring sublines of the MDA-MB-435 cell breast tumor cell line t
191 effect of DDP was assessed using a panel of sublines of the MMR-deficient HCT116 colon carcinoma cel
192 regulation of the Muc4/SMC gene in the 13762 sublines of the rat mammary adenocarcinoma correlates wi
194 and are prominent in the synovial lining and sublining of patients with rheumatoid arthritis (RA).
195 produced by an uncloned transformed (t-SA') subline on a confluent background of nontransformed cell
196 onal derivatives by using two nontransformed sublines, one of which was highly sensitive and the othe
197 vived 21-day exposure to tamoxifen (T-series sublines) or fulvestrant (F-series sublines) and subline
202 iRNA in the paclitaxel-resistant cancer cell sublines partially sensitized these cells toward paclita
203 PC3 and the even more aggressive, metastatic subline PC3M assessed by hyperpolarized in vivo pyruvate
205 tion process to isolate murine mammary tumor sublines possessing an enhanced ability to colonize the
210 ostate cancer xenograft models with isogenic sublines reflecting the transition from androgen-depende
215 stingly, both in vitro- and in vivo-produced sublines resembled the naturally occurring metastatic po
217 paclitaxel selected human ovarian carcinoma sublines, resistant to paclitaxel due to acquired beta-t
218 taII into the differentiation-resistant KG1a subline restored the ability to undergo DC differentiati
221 with the milk and mammary glands of another subline, RIIIS/J, revealed that they do not express MMTV
224 ne but was significantly down-regulated in a subline selected for in vivo tumor formation in Balb/c m
225 ared DU145 humanprostate cancer cells with a subline selected for resistance to camptothecin.Differen
226 numbers of tumor nodules compared with tumor sublines separately expressing low levels of Fas or ICAM
228 x (ECM), 786-O VHL(-) RCC cells and isogenic sublines stably expressing VHL gene products [VHL(+)] we
230 A set of genes strongly expressed in the U-sublines successfully predicted metastasis-free survival
231 n methotrexate (MTX)-resistant CCRF-CEM cell sublines suggested that polyglutamylation was crucial fo
232 binant restoration of EMP2 expression in the subline suppressed its tumorigenicity, suggesting that l
233 induced damage, whereas retinas in the other sublines sustained damage within a sensitive region in t
234 astatic clone of K1735 cells, SW1-C, and its subline SW1-P2, which expresses an activating transcript
235 In the T6 generation, all progeny of one subline, T(3)30, expressed ubiquitin-driven bar and uidA
237 tions of stable expression in the multi-copy subline, T3#30, but not in the other lines studied.
238 s exactly like those in an identical sibling subline, T3#31, which had significant reduction in trans
239 sitization were observed in the vector-alone sublines than in the Ku86-complemented XR-V15B sublines.
240 ates; (c) lack of potentiation in a CCRF-CEM subline that does not express the RFC; and (d) similarit
241 into glyB cells, a Chinese hamster ovary K1 subline that is deficient in the transport of folates in
242 glutamine utilization in the metastatic PC3M subline that led directly to sensitivity to glutaminase
243 atic parental line and to an in vivo-derived subline that was highly metastatic for growth in the lun
244 with a large excess of uncloned cells from a subline that was refractory to transformation markedly d
245 east adenocarcinoma cells (MCF-7E and MCF-7L sublines that are sensitive and resistant to VD3 compoun
246 acts as a chromosomal replicator, HeLa cell sublines that each contain a single copy of the Saccharo
247 ed IGF-I effects in MCF-7 breast cancer cell sublines that have been selected for loss of ERalpha (C4
248 esistance, we characterized MCF-7 monoclonal sublines that survived 21-day exposure to tamoxifen (T-s
250 d by at least a factor of three, and in some sublines the sensitive region was enlarged to include th
251 ed studies performed with a cloned committed subline, the A33 line, verified stable adipocyte lineage
252 -independent and highly malignant Nb2-SFJCD1 subline, the constitutive expression of HRPAP20 was mark
253 of Tiam1 in the migration of these migratory sublines, the parental SW480 cell line was transfected w
258 in hormone-sensitive and hormonal-resistant sublines using Affymetrix Human Genome U133 Plus 2.0 Arr
259 he sarcoma model, a Fas-resistant/refractory subline was produced in vitro from the parental line by
260 FAK binding; additionally, a CD44(-) Jurkat subline was transfected with murine CD44, CD44 with a po
261 as transcripts and protein in the metastatic subline was unaffected by estrogen and ICI 182,780.
262 sed acquisition of surface pre-BCR in BLIN-3 sublines was associated with loss of DJ rearrangements a
265 disrupting the ORF MXAN7041 in two different sublines, we demonstrated substantial epistasis from the
269 5.1 nM), whereas their bortezomib-resistant sublines were 9- and 17-fold cross-resistant to salinosp
272 R-deficient) and HCT116+ch3 (MMR-proficient) sublines were exposed for varying periods of time to an
278 d ICAM-1 regulated malignant behavior, tumor sublines were produced that expressed either lower level
281 ution of paclitaxel resistance, three SKOV-3 sublines were selected during successive rounds of expos
285 that the organism was a member of a distinct subline which includes uncultured Corynebacterium MTcory
286 We exploited this heterogeneity to derive sublines which are highly susceptible to prion infection
287 poietic cell line, Ba/F3, and 3-5 individual sublines which stably overexpressed each transgene were
288 differed significantly from those of the T/F-sublines, whose transcriptomal responsiveness to fulvest
291 rs generated by the MDA-MB-231 breast cancer sublines with characteristically different primary tumor
292 clusions because they worked with transgenic sublines with drifted transgene expression patterns.
294 lay of mRNA expression in prostate carcinoma sublines with varying metastatic potential revealed over
295 howed the bacterium to be a hitherto unknown subline within a group of Actinomyces species which incl
297 ach group may represent a previously unknown subline within the Bacteroides phylogenetic cluster.
299 distinct and represents a previously unknown subline within the Porphyromonas phylogenetic cluster.
300 was restored in the human Ku86-complemented sublines without alteration of cell cycle distributions.
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