ライフサイエンスコーパス: submaximal

1 ed to 6 Hz or less and pressure amplitude is submaximal.

2 all tolerant subjects mainly in response to submaximal 0.1 mug/ml allergen concentration.

3 opic 5-HT3A receptor responses in patches to submaximal (2 microM) and maximal (100 microM) concentra

4 The glucose clamp studies were performed at submaximal (4 mU/kg/min) and maximal (25 mU/kg/min) insu

5 s had worse maximal (peak oxygen uptake) and submaximal (6-min walk distance) exercise capacity (p <

6 decreased the slack sarcomere length (SL) at submaximal activating [Ca(2+)] and increased the steepne

7 We compared contraction kinetics obtained at submaximal activation at steady-state SL with contractio

8 uscle troponin activation increases force at submaximal activation in both wildtype and NEB KO fiber

9 CK-2066260 greatly increased k(tr) at submaximal activation levels in both WT and NEB KO fiber

10 Partial agonists produce submaximal activation of ligand-gated ion channels.

11 Thus, during submaximal activation of muscarinic receptors, V(m) can

12 the high-velocity phase of shortening during submaximal activation with Ca(2+), or on V(o) during max

13 xcess again, the UPR transitions to chronic, submaximal activation, indicating that the UPR senses ER

14 rs between striated muscle cell types during submaximal activations.

15 e determination of mitochondrial function at submaximal activity rates, which is more physiologically

16 age on the hemodynamic response to prolonged submaximal aerobic exercise in healthy volunteers.

17 By stimulating neurons with a submaximal agonist concentration before (R1) and after (

18 Consistent with this result, at submaximal agonist concentrations, the activation kineti

19 sthetics halothane and isoflurane potentiate submaximal agonist responses at wild-type receptors, via

20 calcium, 80 mg/d, or rosuvastatin, 40 mg/d; submaximal: all other dosages).

21 ptosis, however, coexpression of DAP4 with a submaximal amount of MST1 enhances MST1-induced apoptosi

22 ine production by these cells in response to submaximal amounts of anti-CD3 and anti-CD28.

23 refractoriness, these performance gains are submaximal and energetically costly.

24 ed arteriovenous shunting in all subjects at submaximal and in 4/7 subjects at maximal exercise inten

25 f the muscle vasodilatation that accompanies submaximal and maximal contractions.

26 Accommodation was centrally stimulated with submaximal and maximal current amplitudes.

27 sults-- The cardiovascular response to acute submaximal and maximal exercise were assessed before and

28 (MCE) and wall motion analysis (WMA) during submaximal and peak dobutamine stress echocardiography (

29 esting pre- and post- training included: (a) submaximal and peak; (b) prolonged (60 min) submaximal e

30 human dosage of LAmB 3 mg/kg/d resulted in a submaximal antifungal effect.

31 APHR compared with those with normal SE with submaximal APHR (p<0.0001; 95% CI: 2.81 to 5.08).

32 78% higher in patients with abnormal SE with submaximal APHR compared with those with normal SE with

33 Patients with submaximal APHR in the setting of normal SE have a highe

34 Thus, the results of submaximal APHR in the setting of normal SE should be ta

35 This effect is submaximal as CD28 costimulation coupled to TCL1 express

36 EPO induction was submaximal, as hypoxia or pharmacologic PHD inhibition f

37 This effect was time dependent, submaximal at 1 nM, and comparable in potency to epiderm

38 At submaximal ATP concentrations, Ap(5)A stimulated current

39 nner under conditions where Anr activity was submaximal because of the presence of oxygen.

40 Contractile reserve during submaximal beta-adrenergic stimulation is attenuated in

41 Under submaximal beta-adrenoceptor stimulation of brown adipoc

42 ropose that the Apc(1322T) mutation produces submaximal beta-catenin levels that promote early tumor

43 rease in ICa,L sensitivity to stimulation by submaximal beta1-AR activation using isoproterenol (Iso)

44 ter (i) overnight rest (nonexercise) or (ii) submaximal bicycle exercise.

45 <140/90 mm Hg [nonhypertensive]) performing submaximal Bruce treadmill tests were followed for 20 ye

46 Further, failing to consider submaximal but reliable population responses can lead to

47 f partial mGlu5 NAMs, characterized by their submaximal but saturable levels of blockade, may represe

48 ng thin filament activation, particularly at submaximal Ca(2)(+) levels, even though XB-RU cooperativ

49 creased linearly with dATP/ATP ratio, but at submaximal Ca(2+) (pCa 5.5) this relationship was nonlin

50 These effects were greater for submaximal Ca(2+) activated contractions.

51 nd 1.0 mumol/L) enhanced force generation at submaximal Ca(2+) activations in a dose-dependent manner

52 and a slowed rate of XB detachment (krel) at submaximal Ca(2+) activations.

53 ffect, increasing maximal ATPase activity at submaximal Ca(2+) concentrations.

54 tile mechanics were monitored at maximum and submaximal Ca(2+) concentrations.

55 Interestingly, force at submaximal Ca(2+) levels was markedly elevated in single

56 actile activation (kACT) at maximal, but not submaximal Ca(2+), and reduced the Ca(2+) sensitivity of

57 ivate the thin filament regulatory system at submaximal Ca(2+).

58 nd increased recruitment of cross-bridges at submaximal Ca(2+).

59 er the rate of force redevelopment (ktr ) at submaximal [Ca(2+) ].

60 tachment time was significantly prolonged at submaximal [Ca(2+)] (pCa >/=6.5) in HTN patients.

61 ho-MLCK-1 was observed over a broad range of submaximal [Ca(2+)] levels with comparable EC(50) [Ca(2+

62 ay prolonged cross-bridge attachment time at submaximal [Ca(2+)] without a change in the tension-pCa

63 both CPI-17 and myosin light chain (MLC) at submaximal [Ca(2+)]i.

64 At submaximal Ca2+ activation, PKD-mediated phosphorylation

65 e rate of isometric force development during submaximal Ca2+ activations and suggest that the rate of

66 etch of skinned myocardium during maximal or submaximal Ca2+ activations resulted in an instantaneous

67 During submaximal Ca2+ activations, the time course of shorteni

68 enhanced myofilament tension in response to submaximal Ca2+ under physiological ionic conditions.

69 Furthermore, NEM-S1 potentiated submaximal Ca2+-activated forces and thereby increased t

70 found to increase from 1.11 +/- 0.21 s-1 at submaximal [Ca2+] (pCa 6.0) to 9.28 +/- 0.41 s-1 during

71 At submaximal [Ca2+], the thin filament regulatory system m

72 rations, velocity was reduced at maximal and submaximal calcium in the presence of Pi.

73 thin filament activation at both maximal and submaximal calcium levels, with the relative contributio

74 n of myosin strong binding being greatest at submaximal calcium.

75 However, submaximal cAMP-dependent protein kinase activation had

76 tentiation of the Ca(2+)-mediated Isc and of submaximal cAMP-mediated responses.

77 r the entire population and was lower in the submaximal capacity subgroup compared with the maximal c

78 olume responses, or enhance those induced by submaximal [CCh], because the magnitude of the changes w

79 th l-dopa (7 mg/kg ip) that alone produced a submaximal circling response, ST1535 enhanced the intens

80 d alveolar fluid clearance (< 3%/h), 32% had submaximal clearance (> or = 3%/h, < 14%/h), and 13% had

81 se mortality in patients with normal SE with submaximal compared with maximal APHR (relative risk: 1.

82 ine) was 70% higher in patients who achieved submaximal compared with those with maximal APHR (annual

83 ne) was 127% higher in patients who achieved submaximal compared with those with maximal APHR (annual

84 response) and potentiated the responses to a submaximal concentration (1 nm) of insulin.

85 cAMP synthesis was slightly elevated with a submaximal concentration of 7-deacetyl-7-(O-[N-methylpip

86 could amplify the aggregation response to a submaximal concentration of ADP.

87 receptors from rats show potentiation when a submaximal concentration of ATP is combined with zinc in

88 spiking and this effect was additive with a submaximal concentration of AVP (50 pM).

89 ed rather than antagonized the response to a submaximal concentration of clobenpropit.

90 e (alphaEMTBL) potentiates the response to a submaximal concentration of glycine produced by receptor

91 l act as potentiators of responses evoked by submaximal concentrations of 5-HT.

92 of these gene promoters in cells exposed to submaximal concentrations of Akti-1/2; however, full rep

93 The response of P2X(2) receptors to submaximal concentrations of ATP is potentiated by low l

94 ition by antithrombin III in the presence of submaximal concentrations of heparin is reduced for all

95 rtially antagonize Ca(2+) release induced by submaximal concentrations of Ins(1,4,5)P(3), an inhibiti

96 ssium channel (Kir3.X) (GIRK) conductance by submaximal concentrations of Met(5)-enkephalin (ME) and

97 Activation of PKD by submaximal concentrations of phospholipase C-coupled rec

98 rrents increase with repeated application of submaximal concentrations of RTX until a maximal respons

99 Low concentrations of FGF2 combined with submaximal concentrations of T4 produced an additive ang

100 and enhanced cAMP accumulation stimulated by submaximal concentrations of the betaAR agonist isoprote

101 d potentiate receptor activation elicited by submaximal concentrations of the transmitter.

102 Fatigue reduced the complexity of submaximal contractions (ApEn to 0.24 +/- 0.05; SampEn t

103 r power capacity of muscle, which means that submaximal contractions can be sustained after the onset

104 Fresh submaximal contractions were more complex than maximal c

105 Fresh submaximal contractions were more complex than maximal c

106 uring 50% maximal oxygen uptake steady-state submaximal cycling exercise.

107 At room temperature, the SOCE induced by submaximal depletion of the SR Ca(2+) store was signific

108 Studying adult ICU patients receiving VPI at submaximal dosages, we analyzed characteristics of susta

109 nhanced arthritis when coadministered with a submaximal dose of anti-CII antibodies and bound targets

110 Combination therapy with Ad PDGFRbeta and submaximal doses of Ad Flk1-Fc produced modest additive

111 Cotreatment of muscle cells with submaximal doses of INH and insulin resulted in an addit

112 cells promoted the [Ca(2+)]c rise evoked by submaximal doses of IP3, indicating that O2 directly sen

113 given alone and to potentiate the effects of submaximal doses of l-dopa.

114 0 mm l-phenylalanine and 1 microm NPS R-467, submaximal doses of the two agents, each elicited simila

115 regenerative ability in animals treated with submaximal doses of vincristine.

116 th cisplatin, ABDNAZ was better tolerated at submaximal doses, yielding significant tumor growth inhi

117 CI, 0.87-0.94) compared with those receiving submaximal doses.

118 The prognostic value of a negative-submaximal DSE study before noncardiac surgery is unknow

119 ut not glycine activates NMDA receptors with submaximal efficacy.

120 inematics, kinetics, and metabolic demand of submaximal effort movement.

121 Furthermore, pairing submaximal endogenous activation of metabotropic glutama

122 submaximal and peak; (b) prolonged (60 min) submaximal endurance and (c) high-intensity intervals.

123 t maximal ppERK responses initially occur at submaximal ERK levels and that this non-monotonic relati

124 e text]e/[Formula: see text]co2 ratio during submaximal exercise (r=0.780, P<0.001).

125 d anterior myocardial infarction (MI) during submaximal exercise and brief acute circumflex ischemia.

126 The combination of submaximal exercise and hypoxia produces a 'compensatory

127 counterregulatory failure during subsequent submaximal exercise and may increase the risk of exercis

128 titial space was measured at rest and during submaximal exercise at Pre, 1 week and 8 weeks.

129 and left ventricular mass nor did it improve submaximal exercise capacity or quality of life.

130 e and did not have better quality of life or submaximal exercise capacity than did patients who recei

131 d points included change in quality of life, submaximal exercise capacity, and left ventricular eject

132 .min(-1); P=0.003) and significantly reduced submaximal exercise capacity, as determined by the oxyge

133 , improvement in biventricular function, and submaximal exercise capacity.

134 ng the onset of moderate and heavy intensity submaximal exercise in humans.

135 reduces blood pressure and the O(2) cost of submaximal exercise in humans.

136 AMPK, regulates muscle glucose uptake during submaximal exercise in vivo.

137 An additional increase with submaximal exercise occurred in controls only.

138 Submaximal exercise parameters, such as ventilatory effi

139 nction (Short Physical Performance Battery), submaximal exercise performance (6-Minute Walk Test), st

140 le function, pulmonary function, maximal and submaximal exercise performance or quality-of-life quest

141 Maximal and submaximal exercise performance, respiratory and quadric

142 5, 53% women, mean age 59 years) underwent a submaximal exercise test (first 2 stages of the Bruce pr

143 Therefore, this simple, submaximal exercise test might be useful for assessing p

144 rdiorespiratory fitness was assessed using a submaximal exercise test to estimate maximum oxygen cons

145 rform less well either on a 6-minute walk or submaximal exercise testing despite increased right-to-l

146 e lower LVapical rotation at rest and during submaximal exercise that can occur without changes in gr

147 e yearlings were randomly assigned to either submaximal exercise training or no forced exercise (untr

148 from wk 0 to 9, and also not in response to submaximal exercise training.

149 During submaximal exercise workloads (20-60% Wmax), despite an

150 se economy (i.e. metabolic cost of sustained submaximal exercise) does not change with age in enduran

151 (exhaled nitric oxide [NO] production during submaximal exercise) were prospectively assessed in 259

152 During submaximal exercise, HFpEF subjects displayed reduced to

153 hial artery and exhaled NO production during submaximal exercise, is associated with an increased mor

154 Neither prolonged submaximal exercise, nor high-intensity intervals, nor s

155 During submaximal exercise, physiological mitochondrial fragmen

156 During submaximal exercise, the transpulmonary gradient and pul

157 diastolic untwisting rate (UTR) at rest and submaximal exercise.

158 roved ventilatory efficiency during peak and submaximal exercise.

159 kle tracking echocardiography at rest and on submaximal exercise.

160 iting to fat oxidation during high intensity submaximal exercise.

161 al responses were observed during prolonged, submaximal exercise.

162 does not limit PCr kinetics at the onset of submaximal exercise.

163 ) at a given oxygen consumption (VO2) during submaximal exercise.

164 s with PH were unable to increase Ees during submaximal exercise.

165 epletion and lactic acid accumulation during submaximal exercise; this adaptation is mediated by an i

166 During submaximal exertion at comparable heart rates (114+/-6 v

167 -ineffective dose of Jas plus a threshold or submaximal facility-effective dose of the actin depolyme

168 l activity while they performed two types of submaximal fatiguing isometric contraction that required

169 The augmentation of submaximal force by NEM-S1 was accompanied by a marked r

170 vation and relaxation kinetics nor the final submaximal force development differed significantly betw

171 ent and rate of relaxation from steady-state submaximal force following flash photolysis of the caged

172 Significantly, at equivalent levels of submaximal force k(tr) was faster at short SL or increas

173 Fluctuations in F(z) during the submaximal force-matching tasks were 2.45x greater (p<.0

174 blation of cMyBP-C-accelerated k(tr) at each submaximal force.

175 d ability to accurately and steadily control submaximal force; and impaired eccentric strength.

176 mal voluntary contractions (MVCs) and steady submaximal forces (2.5 and 10% MVC) with the fingertip o

177 t the effects of NEM-S1 to increase k(tr) at submaximal forces and thereby markedly reduce the activa

178 nesin-2 motors were more likely to detach at submaximal forces, and the duration of force maintenance

179 rrents activated more slowly when exposed to submaximal GABA concentrations, had more fast desensitiz

180 iazepam, only potentiate currents induced by submaximal GABA concentrations.

181 esthetics potentiate the currents induced by submaximal GABA concentrations.

182 of propofol or pregnanolone to potentiate a submaximal GABA response, but the Q185A mutant exhibited

183 Agonists at the BDZ binding site potentiate submaximal GABA responses by increasing the apparent aff

184 Potentiation of submaximal GABA(A) receptor currents by the neurosteroid

185 Low concentrations potentiate submaximal GABA-induced currents.

186 objective was to delineate the prevalence of submaximal gamma-carboxylation as assessed by response t

187 secrete adenosine diphosphate in response to submaximal gamma-thrombin concentrations that cause secr

188 nhanced ruffling and pinocytosis produced by submaximal GH but not submaximal PDGF.

189 A clear hypersensitivity to submaximal glucose concentrations was evident in INS-1 c

190 S), but only in the presence of intermediate/submaximal glucose concentrations.

191 concentrations, but were most pronounced at submaximal glucose levels.

192 onal cell death, however, when combined with submaximal glutamate (3.3 mM), TNF alpha significantly i

193 To estimate physical fitness, a submaximal graded exercise test was performed on a bicyc

194 from previously diagnosed CVD who underwent submaximal graded exercise treadmill testing to achieve

195 ency among the negative-maximal and negative-submaximal groups (6 of 335, 1.8% vs. 1 of 62, 1.6%, res

196 mal cardiac output (21.4 versus 21.7 L/min); submaximal heart rates also declined to a similar degree

197 Because wild-type mice exhibited submaximal HIF accumulation in response to no-flow ische

198 ditions where thin filament sliding speed is submaximal (i.e. in the presence of troponin and tropomy

199 At moderate buffer strengths, submaximal ICRAC is evoked by maximal InsP3.

200 in METH-pretreated D(2) mutants but remained submaximal in METH-pretreated D(3) mutants.

201 All identified TrbA operators are submaximal; in the case of trbBp, a G to A transition th

202 at prevents a supply-demand imbalance during submaximal increases in cardiac workload when coronary f

203 They felt this submaximal index of cardiopulmonary reserve might be mor

204 duction response could be heterogeneous at a submaximal inducer concentration.

205 y cytoprotective at concentrations that gave submaximal inhibition of macroscopic currents in oocytes

206 f InsP(3)R2 was enhanced by ATP, but only at submaximal InsP(3) levels.

207 sP(3)-mediated Ca(2+) release in response to submaximal InsP(3) stimulation in permeabilized wild-typ

208 tal muscle, glucose transport in response to submaximal insulin (450 microU/ml) was measured in isola

209 % increase in glucose disposal (p < 0.05) at submaximal insulin but no increase at maximal insulin co

210 This submaximal insulin concentration promotes an intermediat

211 nhanced insulin-stimulated glucose uptake at submaximal insulin concentrations and reversed the inhib

212 At submaximal insulin doses, protection was potentiated by

213 Relative to WL5, submaximal insulin-stimulated 2-deoxyglucose uptake into

214 eceptor beta-subunit (IRbeta) protein level, submaximal insulin-stimulated IRbeta tyrosine phosphoryl

215 sine phosphorylation of the IR stimulated by submaximal insulin.

216 , or underwent 30 min of electrically evoked submaximal intensity isometric contraction using a perfu

217 control subjects without PH who performed a submaximal invasive cardiopulmonary exercise test betwee

218 lso facilitated the Ca(2+) release evoked by submaximal IP3 in permeabilized DKO1 and DKO2 but was in

219 ts with chronic stroke performed a series of submaximal isometric elbow flexion tasks.

220 was decreased from 2.3 microm to 2.0 microm submaximal isometric force decreased approximately 40% i

221 During submaximal LBNP, FVR increased in HT (ANOVA P < 0.05) bu

222 and forearm vascular resistance (FVR) during submaximal LBNP.

223 endent translation, which is maintained at a submaximal level during hypertrophic growth and point to

224 eveloped antiphage antibodies that reached a submaximal level within the 10-day protocol window for s

225 Repeated administration of C75 at a submaximal level, however, differentially affected food

226 of Rac1 maintains the number of spines at a submaximal level.

227 ondrial function in human skeletal muscle at submaximal levels and at a predefined membrane potential

228 IRES activity is then maintained at submaximal levels during hypertrophic growth of these ce

229 force was inhibited by Vi k(TR) increased at submaximal levels of Ca(2+)-activated force.

230 Plant populations frequently maintain submaximal levels of resistance to natural enemies, even

231 At similar submaximal levels of steady-state force there was no inc

232 nstrate that both Bmp and Wnt are present at submaximal levels, which allows the pathways to function

233 ontraction and MAS of the knee flexors using submaximal loads relative to the individual's maximum vo

234 synapse and activation of mGlu7 potentiated submaximal LTP.

235 These data suggest that during submaximal metabolic rates, the relationship between (.-

236 rogressively recruited for the full range of submaximal muscle activation in all conditions.

237 controlling human eccentric than concentric submaximal muscle contractions.

238 When cytoplasmic Na is submaximal, Na/K pump currents decay rapidly during extr

239 In cultures treated with submaximal NMO-IgG, the severity of NMO lesions was incr

240 y 25% had impaired clearance whereas 75% had submaximal or maximal clearance.

241 inocytosis produced by submaximal GH but not submaximal PDGF.

242 on, indicating a linear relationship between submaximal peptide concentration and response of the SN.

243 augmentation of response frequencies at all submaximal peptide doses by CD28- and CD49d-mediated cos

244 ealthy subjects, with better preservation of submaximal performance.

245 ther the background statin was of maximal or submaximal potency.

246 a suggest that integrase has evolved to have submaximal processing activity so that it can also catal

247 in accurately matching target forces during submaximal quadriceps contractions and in the same tasks

248 sometric and isokinetic force in response to submaximal rates of nerve stimulation in situ producing

249 ndlimb muscle force and power in response to submaximal rates of nerve stimulation in situ.

250 vidence that enhancer specificity depends on submaximal recognition motifs having reduced binding aff

251 increases to attain this maximum (or to its submaximal requirement), and even less to the kinetic fe

252 on than with enteral nutrition that approach submaximal response levels and direct appearance of admi

253 TDBzl-etomidate (>10 microm) increased the submaximal response to acetylcholine (10 microm) with a

254 ), and higher Zn2+ concentrations inhibiting submaximal responses to glycine.

255 The prognostic value of a normal but submaximal SE (<85% of maximal APHR) is conflicting.

256 r or shorter than this optimal length elicit submaximal spike responses.

257 quency and duration of channel openings to a submaximal state.

258 Among patients who arrived on submaximal statins, 26% had their statin therapy intensi

259 rt rate measurement following a standardized submaximal step test; muscular fitness was assessed by m

260 nd concentration-dependent force increase at submaximal stimulation frequencies.

261 However, at submaximal stimulation frequency, force was reduced in K

262 enhance activation of neutrophils exposed to submaximal stimulatory doses of LPS.

263 by 45% (p<0.05) the area of the AP evoked at submaximal stimulus intensity.

264 157% (p<0.05) the area of the AP evoked at a submaximal stimulus intensity.

265 vity than WMA, particularly in patients with submaximal stress and in identifying patients with multi

266 (CFR) by positron emission tomography, where submaximal stress precludes assessing physiological seve

267 phic examination with DTI at rest and during submaximal supine bicycle exercise.

268 ing NW width, and the selectivity to measure submaximal synaptic concentrations of DA in the presence

269 Administration of submaximal tamoxifen allowed genetic labeling of single

270 e or muscarinic acetylcholine receptors with submaximal TBF unmasked associative iLTD.

271 ited immunosuppression, or in the context of submaximal TCR or costimulatory signals, targeting of PD

272 raded, progressive protocol, and a prolonged submaximal test (70% peak intensity for 45 min) were adm

273 maximal voluntary contractions, MVCs), and a submaximal test (contractions at a target of 40% MVC per

274 n uptake (VO2max) per kg)) was measured in a submaximal test.

275 Perceived dyspnea during the submaximal testing was decreased.

276 this is also true among patients undergoing submaximal testing.

277 lcysteine (SNAC) and spermineNONOate reduced submaximal tetanic and peak twitch forces.

278 l ester (L-NAME, a NOS inhibitor), increased submaximal tetanic and peak twitch forces.

279 A submaximal tetanic stimulation (2x50 Hz/1 s) in control

280 Schaffer collateral-CA1 synapses, while the submaximal tetanus now elicited frank LTD of synaptic EP

281 atients, intensification in those undergoing submaximal therapy, and discharge on maximal therapy (de

282 Thus, there is a submaximal threshold of FPR phosphorylation that simulta

283 e of proteasome inhibitors, in particular at submaximal TRAIL doses.

284 12) and kidney (HEK 293T) cells, producing a submaximal transcriptional response (1.8- to 2.5-fold ac

285 microsphere infusions) were measured during submaximal treadmill running (20 m min(-1), 5% grade).

286 Of 4,860 eligible for a submaximal treadmill test, 3,250 completed the test and

287 Subjects also completed a submaximal treadmill test, Timed-Stands Test, and 50-Foo

288 tween the HAP scores and the questionnaires, submaximal treadmill test, Timed-Stands Test, and 50-Foo

289 jects with arthritis completed the HAP and a submaximal treadmill test.

290 VO(2max) was estimated from the submaximal treadmill test.

291 diovascular performance throughout prolonged submaximal upright cycle ergometry in 40 carefully scree

292 c reserve performance occur during prolonged submaximal upright cycle ergometry, analogous to those o

293 Below CS V(O2) stabilized at a submaximal value (58.5 +/- 2.5 ml kg(-1) min(-1)) wherea

294 lex than maximal contractions (mean +/- SEM, submaximal vs. maximal: ApEn 0.65 +/- 0.09 vs. 0.15 +/-

295 plex than maximal contractions (mean +/- SEM submaximal vs. maximal: ApEn 0.65 +/- 0.09 vs. 0.15 +/-

296 iovascular response to prolonged exercise at submaximal work rates typical of daily aerobic activitie

297 At submaximal work rates, there was no significant differen

298 e heart rate response to reference levels of submaximal work.

299 outs (5 min duration; order randomised) at a submaximal workload while breathing 0.1, 0.21 or 1.0 F(I

300 d rate-pressure product (RPP) at maximal and submaximal workloads were assessed.