ライフサイエンスコーパス: submembrane

1 ne and associated with disrupted TLR9 at the submembrane.

2 esting that they may translocate against the submembrane actin cortex.

3 extracellular environment with the parasite submembrane actomyosin motor.

4 gold particles/microgram 2 cytoplasm in the submembrane and the central region of intracapillary neu

5 t elevation in K(ATP) p(open) may arise from submembrane ATP depletion by the Na(+)-K(+) ATPase, as t

6 ump interacts with KATP current (IK-ATP) via submembrane ATP depletion in isolated giant membrane pat

7 can be observed with widely varying apparent submembrane [ATP] ([ATP](sub)).

8 On a long-range scale (>250 nm), submembrane barriers, or skeleton fences that hinder lon

9 ulses (10-100 ms) lead to the development of submembrane Ca(2+) gradients, as previously described.

10 We demonstrate that a rise in submembrane Ca(2+) induces a large decrease in T-type cu

11 NCAM2-dependent submembrane [Ca(2+)] spikes colocalize with the bases of

12 ll surface of mouse cortical neurons induces submembrane [Ca(2+)] spikes, which depend on the L-type

13 We then used this relationship to infer the submembrane [Ca(2+)](i) ([Ca(2+)](sm)) sensed by NCX dur

14 X current (INCX) was used to infer the local submembrane [Ca]i ([Ca]sm) that is sensed by NCX dynamic

15 it has become clear that cyclic variation of submembrane [Ca2+] and activation of the Na+-Ca2+ exchan

16 to more negative potentials by increases in submembrane [Ca2+] from 1 to 60 microM.

17 to embrace the impact of cyclic variation in submembrane [Ca2+] on pacemaker function.

18 Submembrane [Ca2+]i changes were examined in rat chromaf

19 This information was used to examine submembrane [Ca2+]i elevations arising out of Ca2+ influ

20 Submembrane [Ca2+]i elevations fall rapidly after termin

21 In contrast to influx, the submembrane [Ca2+]i elevations produced by release of in

22 ities of transient and nonuniform changes in submembrane calcium concentration produced by voltage-ga

23 and illustrate the functional importance of submembrane calcium microdomains.

24 at PDE2 mediates NP/cGMP-driven decreases of submembrane cAMP levels.

25 pled exocytosis apparently requires elevated submembrane cation concentrations that dissipate rapidly

26 A model consisting of two submembrane (caveolar and extracaveolar) microdomains an

27 In control rabbits, the ratio of submembrane/central gold was always greater than one and

28 The ratio of submembrane/central gold was greater in complement-treat

29 Collybistin promotes submembrane clustering of gephyrin and is essential for

30 Submembrane colocalization of NCX1 and cardiac RyR (cRyR

31 y transmission of energetic signals into the submembrane compartment synchronizing K(ATP) channel act

32 This complex localizes in a submembrane compartment where cAMP synthesis occurs.

33 s, but may control cAMP levels in restricted submembrane compartments that are defined by small volum

34 rane lipid composition varies greatly within submembrane compartments, different organelle membranes,

35 likely due to restricted cAMP diffusion from submembrane compartments.

36 oteolytic processing of SOAF from sperm head submembrane compartments.

37 in family are ubiquitous constituents of the submembrane cortex, especially in epithelial cells.

38 and then interact with specific sites on the submembrane cortex.

39 and beta-Spectrin are major components of a submembrane cytoskeletal network connecting actin filame

40 Dystrophin is a large, submembrane cytoskeletal protein, absence of which cause

41 might serve to anchor NMDA receptors to the submembrane cytoskeleton and aid in the assembly of sign

42 n does not depend on membrane trafficking or submembrane cytoskeleton and has no effect on GJ conduct

43 n, and associated molecules form a periodic, submembrane cytoskeleton in the axons of neurons.

44 These results suggest that an apical submembrane cytoskeleton of intermediate filaments is ex

45 ments may function as a novel element of the submembrane cytoskeleton of spines.

46 on of "extracellular matrix-surface membrane-submembrane cytoskeleton" assembly of the NK-sensitive T

47 ated proteins that are key components of the submembrane cytoskeleton.

48 s used for optical imaging of exocytosis and submembrane depolarization-evoked [Ca(2+)](i).

49 ed that GLP-1 activates PLC, which increases submembrane diacylglycerol and thereby activates PKC, re

50 calize the enzyme to specific subcellular or submembrane domains.

51 In contrast, ANP elicited sustained submembrane elevations in [cGMP](i), which were converte

52 interactions enhance the functioning of the submembrane exocytic machinery.

53 e membrane by altering the properties of the submembrane F-actin and/or its attachment to the membran

54 Cytoskeletal rearrangements, as assessed by submembrane F-actin rims, result in poorly deformable ne

55 For submembrane fluorescence-marked actin, the intensity, of

56 ws that a 30 min incubation of spinach PS II submembrane fragments at pH 6.3 in the presence of 10 mi

57 Here, we discuss how receptor submembrane localization and the formation of alternate

58 oncluded that both substrate specificity and submembrane location are critical to phosphatase-mediate

59 l development and originates from sperm head submembrane matrices.

60 ty of collybistin to translocate gephyrin to submembrane microaggregates in transfected mammalian cel

61 , it is necessary to accurately estimate the submembrane Na(+) concentration ([Na(+)]sm).

62 However, larger rises in submembrane [Na+] ([Na+]sm) local to Na+-Ca2+ exchangers

63 suggest that micromolar [Ca(2+) ]i , in the submembrane or junctional cleft space, is not required t

64 ithin the membrane (the sarcoglycans), and a submembrane protein (utrophin).

65 oviding a mechanism for assembly of distinct submembrane protein complexes.

66 in some cells result in local proteolysis of submembrane proteins, leading to generation of membrane

67 istribution of actin from the central to the submembrane region and the microvilli and result in more

68 neutrophils by altering the stiffness of the submembrane region and/or by preventing the microvilli f

69 fening required F-actin formation within the submembrane region but not microtubule rearrangement in

70 phils also contained more F-actin within the submembrane region than circulating neutrophils when exa

71 xes depend on the Na(+) concentration in the submembrane region, it is necessary to accurately estima

72 rger in the interior of the cell than in the submembrane region.

73 olocalizes with GLUT4 in perinuclear but not submembrane regions visualized by confocal total interna

74 Inclusion of adjacent submembrane residues of L0, the linker between TMD0 and

75 g of these receptors, for recruitment of the submembrane scaffold protein gephyrin to postsynaptic si

76 Zonula occludens-1 (ZO-1) is a submembrane scaffolding protein that may display proinva

77 sts that specific AKAPs direct the kinase to submembrane sites to facilitate phosphorylation and modu

78 from cell populations, single cells, and the submembrane space of a single cell.

79 r, revealed a diffusional barrier within the submembrane space, preventing direct reception of cytoso

80 with different dynamic Ca(2+) signals in the submembrane space, the cytosol, and the nucleus.

81 lations, single cells, and the intracellular submembrane space, we have demonstrated in a model liver

82 and the remaining 80% probably occurs in the submembrane space.

83 orylation and regulation were facilitated by submembrane targeting of protein kinase A (PKA), through

84 t CTLA-4 proteins were localized in Tregs in submembrane vesicles that rapidly recycled to/from the c