ライフサイエンスコーパス: submicroscopic

1 s) with one additional GSD I patient showing submicroscopic 6q14.1 deletion.

2 togenetic anomaly of chromosome 7 revealed a submicroscopic allelic imbalance for a third distal locu

3 liposomes resulted in their conversion into submicroscopic alpha-gal nanoparticles.

4 ve been demonstrated to be the most frequent submicroscopic alterations in cytogenetically normal acu

5 ene (n = 8) and trisomy 8 (n = 3), recurrent submicroscopic alterations, including acquired uniparent

6 However, many asymptomatic infections are submicroscopic and can only be detected by molecular met

7 of gametocyte carriers are asymptomatic and submicroscopic and represent a challenge to malaria cont

8 nt excitation lead to a method of creating a submicroscopic area of total internal reflection illumin

9 Because of submicroscopic bacteremia, microscopy can be insensitive

10 Moreover, submicroscopic BCAs and subarray threshold CNVs are intr

11 ion of Ag-containing membranes, formation of submicroscopic BCR oligomers, and recruitment and activa

12 When transmission reaches very low levels, submicroscopic carriers are estimated to be the source o

13 delineation of many previously unrecognized submicroscopic chromosomal aberrations (genomic disorder

14 isk variants and rarer more highly penetrant submicroscopic chromosomal deletions and duplications, k

15 d that the technique is capable of detecting submicroscopic chromosomal DNA deletions.

16 tools designed to aid the interpretation of submicroscopic chromosomal imbalance, inversions, and tr

17 Genomic mechanisms for these submicroscopic chromosomal rearrangements remain unknown

18 artificial chromosome microarray to identify submicroscopic chromosomal rearrangements specific to au

19 Submicroscopic chromosome 7q11.23 deletions cosegregate

20 found that the t(4;19) is associated with a submicroscopic chromosome duplication involving a 19p ch

21 croscopically detectable rearrangements, and submicroscopic copy-number variants (CNVs), which collec

22 The discovery of submicroscopic copy-number variations (CNVs) present in

23 ons vividly shows regions of microscopic and submicroscopic curvature of the membrane, and also gives

24 We report two submicroscopic de novo deletions of 11p13 that cause ani

25 A submicroscopic deletion containing SOX2 was identified a

26 This submicroscopic deletion is readily detected by fluoresce

27 with this inheritance pattern, 51 carried a submicroscopic deletion of 1q21.1 that has previously be

28 Neurofibromatosis type 1 patients with a submicroscopic deletion spanning the NF1 tumor suppresso

29 at the mutation is associated with a <170 kb submicroscopic deletion that includes the anonymous micr

30 Our data also suggest that submicroscopic deletion, but not large deletions, is the

31 3 GTS patients and 1571 control subjects for submicroscopic deletions and duplications of these four

32 marily because of its higher sensitivity for submicroscopic deletions and duplications.

33 ysis of 9 DS-ALL cases identified additional submicroscopic deletions in key genes, including ETV6, C

34 of HTX1 localization, a PCR-based search for submicroscopic deletions in this region was performed in

35 h mental retardation and overlapping de novo submicroscopic deletions of 15q24 (1.7-3.9 Mb in size).

36 ity or replication stress can generate large submicroscopic deletions of the type seen in cancer cell

37 ndrome is a rare genetic disorder, caused by submicroscopic deletions on chromosome 15q.

38 uffering from developmental disorders harbor submicroscopic deletions or duplications that, by affect

39 tu hybridization on cells from patients with submicroscopic deletions to narrow the candidate region

40 It is associated with visible or submicroscopic deletions within chromosome band 17p13.3.

41 rbored asexual stages, or had gametocytes at submicroscopic densities.

42 h histologically negative SLNs, detection of submicroscopic disease by tyrosinase RT-PCR does not def

43 that use methodologies capable of detecting submicroscopic disease can distinguish subgroups of pati

44 could improve prognostication by identifying submicroscopic disease during remission.

45 tudies establish MA-TIRFM for measurement of submicroscopic distances between fluorescent probes and

46 tware, pixel by pixel, generating a range of submicroscopic distances between QD pairs.

47 ctrons, was developed for the measurement of submicroscopic distances.

48 Over recent years small submicroscopic DNA copy-number variants (CNVs) have been

49 ndent spectral shifts; 2), identification of submicroscopic domains by fluorescence lifetime imaging

50 ly contribute to cAMP gradients occurring in submicroscopic domains.

51 transmembrane proteins into microscopic and submicroscopic domains.

52 identified seven unrelated individuals with submicroscopic duplication in 17p13.3 involving the PAFA

53 A submicroscopic duplication that contains the entire prot

54 Cryptic, submicroscopic duplications were observed at or near the

55 in whole organisms, tissues, organelles, and submicroscopic environments in which measurements were p

56 elation between the outcome of treatment and submicroscopic evidence of residual disease.

57 Thirteen percent to 23% of clones exhibited submicroscopic FHIT deletions spanning approximately 200

58 Acute leukemia genomes commonly harbor submicroscopic gains and deletions of DNA which target k

59 transmission is much less likely to occur at submicroscopic gametocyte levels.

60 These studies have identified cryptic or submicroscopic genetic alterations that define new ALL s

61 Multiple submicroscopic genetic alterations with prognostic signi

62 Multiple submicroscopic genetic alterations with prognostic signi

63 of aneuploidy, transcriptional profiles and submicroscopic genetic alterations.

64 rs are the clinical conditions manifested by submicroscopic genomic rearrangements including copy num

65 Submicroscopic gold particle suspensions scatter colored

66 Secretory cells contain submicroscopic granules composed of a polyanionic polyme

67 nges allow for the routine identification of submicroscopic imbalances in large numbers of patients.

68 lciparum and 87% of P. vivax infections were submicroscopic in 2014.

69 ming of interventions, which need to include submicroscopic infections and be implemented in the dry

70 in patients with early-stage malaria and/or submicroscopic infections and could greatly benefit mala

71 enabling improved detection of asymptomatic submicroscopic infections and dramatic savings in labor

72 fects on the proportions of asymptomatic and submicroscopic infections and on transmission potential

73 Prospectively, submicroscopic infections at inclusion were associated w

74 Molecular methods can detect submicroscopic infections but have not hitherto been ame

75 Submicroscopic infections during pregnancy were associat

76 asites and shows promise as a tool to detect submicroscopic infections in malaria control and elimina

77 To eliminate malaria, surveillance for submicroscopic infections is needed.

78 Quantifying these submicroscopic infections is therefore key to understand

79 variate analyses, we evaluated the impact of submicroscopic infections on maternal anemia, premature

80 ominent roles for infections in children and submicroscopic infections.

81 e considered differences in estimates due to submicroscopic infections.

82 logical factors associated with low-density, submicroscopic infections.

83 -reducing interventions require knowledge of submicroscopic infectious reservoirs among asymptomatic

84 1 deletion resulted from a maternal balanced submicroscopic insertional translocation of the entire P

85 associated gene rearrangements in tumors are submicroscopic, intralocus deletions of hundreds of kilo

86 current chromosome macrorearrangements and a submicroscopic inversion polymorphism.

87 All the mothers were heterozygous for an 8p submicroscopic inversion that was delimited by the 8p-OR

88 eatment response assessed by measurements of submicroscopic leukaemia (minimal residual disease) has

89 e investigated retrospectively the impact of submicroscopic leukemia on outcome in 64 patients receiv

90 mu, and pfubp1 more often survive ACT at the submicroscopic level, and contribute to onward transmiss

91 The clinical significance of submicroscopic levels of leukaemic cells in bone-marrow

92 Even submicroscopic levels of Plasmodium falciparum gametocyt

93 a companion article we present the idea that submicroscopic light-scattering particles, such as gold

94 chor on a protein is sufficient to determine submicroscopic localization within the plasma membrane.

95 llite markers enabling the identification of submicroscopic losses.

96 there is some evidence that individuals with submicroscopic malaria can infect mosquitoes, transmissi

97 should strive to define the degree to which submicroscopic malaria contributes to the infectious res

98 The use of an RT-PCR assay for detection of submicroscopic melanoma metastases in SLNs improved the

99 alf was submitted for molecular detection of submicroscopic metastases using a reverse transcriptase-

100 uring the past 2 decades, and measurement of submicroscopic (minimal) levels of residual disease (MRD

101 an image-like spatial map of the rapidity of submicroscopic motions of scattering centers.

102 ome lipid mixtures form membranes containing submicroscopic (nanodomain) ordered lipid domains (rafts

103 identification of additional cell lines with submicroscopic or larger deletions of the locus which oc

104 study, we document the deleterious impact of submicroscopic P. falciparum parasitemia during pregnanc

105 atic malaria cases with the aim of detecting submicroscopic P. knowlesi in this population.

106 We identified submicroscopic PAR1 deletions encompassing the recently

107 participants of cohort 2 developed transient submicroscopic parasitaemia.

108 We show that submicroscopic parasite carriage is common in adults, in

109 Residual submicroscopic parasitemia is common after ACT and is as

110 In addition, submicroscopic particles which scatter blue, green, yell

111 298 ACT-treated children from Mbita, Kenya, submicroscopic persistence of P. falciparum on day 3 pos

112 widely reported, the extent of asymptomatic, submicroscopic Plasmodium knowlesi parasitemia is unknow

113 ical features, and also in less visualizable submicroscopic regions of activity such as endocytosis,

114 The extent of the submicroscopic reservoir needs to be taken into account

115 r lipid membranes (SLM) have been studied at submicroscopic resolution using atomic force microscopy

116 structural alterations in these regions at a submicroscopic scale.

117 alterations in ALL have identified multiple submicroscopic somatic mutations targeting key cellular

118 tically heterogeneous and porous matter with submicroscopic spatial resolution in aqueous solution.

119 plasma membrane are known to partition into submicroscopic sphingolipid- and cholesterol-rich domain

120 and leukaemic cell DNA has identified novel submicroscopic structural genetic changes and sequence m

121 revealed subcellular heterogeneities in the submicroscopic structure of cytoplasm.

122 unclear whether the remaining patients have submicroscopic systemic disease and, if so, what is the

123 g constants of these helices depend on their submicroscopic thickness.

124 es (pcTALM), complex assembly within dynamic submicroscopic zones was identified.